Eurachem and CITAC welcome analysts interested in the evaluation of chemical analysis uncertainty and in how to use this information in results interpretation. The Eurachem Week 2026 will begin with a training course on “Evaluation of the measurement uncertainty from in-house precision and recovery data” scheduled for Sunday, 10 May 2026. A two-days workshop on “Quality in Analytical Measurements: Uncertainty Evaluation and Results Interpretation” open to all interested participants will take place from 11 to 12 May 2026. On 13 May 2026, the Eurachem Working Groups will convene, followed by the Eurachem General Assembly, which will bring together the Executive and national delegates on 14 and 15 May. Both Working Group Meetings and the General Assembly are restricted to their members.The results of qualitative and quantitative chemical analyses should have an acceptable uncertainty, which should ideally be reported and considered in results interpretation.For many analytical applications, simplified uncertainty evaluations can determine uncertainty values that meet the defined requirements for this parameter. The workshop will focus on the key technical challenges involved in practical evaluations of measurement uncertainty based on precision and recovery data gathered during in-house method validation and quality control. There will be a discussion of how to model the variation of the measurement uncertainty within the analytical range and how to handle divergent recovery values from the analysis of various reference materials. A session on the use of measurement uncertainty in conformity assessment will explore how the risk of false conformity decisions can be managed.<blockquote><h5>New Eurachem guidance on using in-house precision and recovery data will be discussed at the workshop.</h5></blockquote>Topics will also include the validation and uncertainty evaluation for qualitative analyses with particular attention to current accreditation requirements for these types of analysis. The last session of the workshop will be dedicated to the evaluation of measurement uncertainty arising from sampling and using it to judge the fitness for purpose, and hence validation, of measurement procedures that include sampling. Four sessions of the workshop will include engaging breakout sessions where participants will have the chance to share their views about challenging aspects of the analytical work. Participants are invited to propose posters and oral communications on session topics or any other relevant topic for analytical chemists or stakeholders of the analytical work.<h3>Registration</h3><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://conferences.chemistry.pt/register/eurachem2026">Register here for the workshop</a></blockquote><h4>Registration Fees</h4><h5>Early bird (EUR) - Until April 15th</h5><ul><li>Workshop: Regular participant (11 &amp; 12 May 2026): 400 EUR</li><li>Workshop: Student (11 &amp; 12 May 2026): 250 EUR</li><li>Eurachem Working Group1 (13 May 2026): 75</li><li>General Assembly2 (14 &amp; 15 May 2026): 250</li><li>Training On Uncertainty Evaluation3 (10 May 2026): 150</li></ul><h5>After April 15th</h5><ul><li>Workshop: Regular participant (11 &amp; 12 May 2026): 450 EUR</li><li>Workshop: Student (11 &amp; 12 May 2026): 300 EUR</li><li>Eurachem Working Group1 (13 May 2026): 100</li><li>General Assembly2 (14 &amp; 15 May 2026): 300</li><li>Training On Uncertainty Evaluation3 (10 May 2026): 200</li></ul><blockquote>§ - 50 EUR reduction for members of Eurachem, CITAC, SPQ, RELACRE, ForMEQ and SPMet at the workshop.10% reduction for organisations that registered more than one participant.1 - Working group members2 - Eurachem members3 - 50% reduction for workshop participants</blockquote><h3>Workshop</h3><h4>Eurachem/CITAC Workshop on Quality in Analytical Measurements:</h4><h5>Uncertainty Evaluation and Results Interpretation</h5>The results of qualitative and quantitative chemical analyses should have an acceptable uncertainty, which should ideally be reported and considered in results interpretation. For many analytical applications, simplified uncertainty evaluations can determine uncertainty values meeting defined requirements for this parameter. The workshop will focus on the key technical challenges involved in practical evaluations of measurement uncertainty based on precision and recovery data gathered during in-house method validation. It will be discussed how to model the variation of the measurement uncertainty within the analytical range and how to handle divergent recovery values from the analysis of various reference materials. A session on the use of measurement uncertainty in conformity assessment will explore how the risk of false conformity decisions can be managed.Topics will also include the validation and uncertainty evaluation of qualitative analyses with particular attention to current accreditation requirements for these types of analysis. The last session of the workshop will be dedicated to the evaluation of measurement uncertainty arising from sampling and using it to judge the fitness for purpose, and hence validation, of measurement procedures that include sampling.Four sessions of the workshop will include engaging breakout sessions where participants will have the chance to share their views about challenging aspects of the analytical work. Participants are invited to propose posters and oral communications on session topics or any other relevant topic for analytical chemists or stakeholders of the analytical work.<h3>Training Course</h3><h4>Evaluation of the measurement uncertainty from in-house precision and recovery data</h4><ul><li>10 May 2026</li></ul>A course on the fundamentals of the evaluation of the measurement uncertainty from in-house precision and recovery data will be held on Sunday, 10 May 2026. This training is targeted for analysts with a basic understanding of the measurement uncertainty concept, how uncertainty components propagate, and how the combined uncertainty is expanded. Following the morning presentation of the theory of uncertainty evaluation, the afternoon will be dedicated to applying the theory to real-world cases. Trainees should have basic skills in using Microsoft Excel spreadsheets and bring a laptop with Microsoft Excel to complete the exercises. The interaction between trainers and trainees will be promoted to guarantee learning efficiency.<h5>Trainers:</h5><ul><li>Ricardo Bettencourt da Silva, Faculdade de Ciências da Universidade de Lisboa, Portugal (rjsilva@ciencias.ulisboa.pt)</li><li>Stephen L. R. Ellison - UK National Measurement Laboratory (NML) hosted at LGC, United Kingdom</li><li>Vicki Barwick - UK National Measurement Laboratory (NML) hosted at LGC, United Kingdom</li></ul><h4>Agenda</h4><h5>8:00 Registration</h5><h5>9:00 Opening</h5><h5>9:05 Identifying, combining, and expanding uncertainty components: Theory and examples</h5><h5>9:45 Precision uncertainty: Theory and examples</h5><h5>10:30 Coffee break</h5><h5>10:50 Trueness-related uncertainty: Theory and examples</h5><h5>12:00 Additional questions and discussion</h5><h5>12:30 Lunch</h5><h5>13:30 Application example 1</h5><h5>15:30 Coffee break</h5><h5>15:50 Application example 2</h5><h5>17:00 Additional questions and discussion</h5><h5>17:30 Closing</h5><h3>Venue</h3>The series of Eurachem events will be held in:<ul><li>Meliã Lisboa Aeroporto ****</li><li>Rua C,2 1749-125 Lisboa, Portugal&nbsp;</li></ul>

Eurachem/CITAC Workshop on Quality in Analytical Measurements 2026

Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 9th February 2026? Check out new documents from the field of spectroscopy/spectrometry and related techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">LabRulezGCMS</a> libraries.</blockquote>This week we bring you application notes by Agilent Technologies, Metrohm, Shimadzu and Thermo Fisher Scientific!<h3>1. Agilent Technologies: Black Pepper Origin Differentiation Using Large ICP-MS Datasets and Chemometric Tools</h3>Elemental profiling using an <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?manufacturerItems=1&amp;search=7850+ICP-MS">Agilent 7850 ICP-MS</a> and Agilent <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?manufacturerItems=1&amp;search=Mass+Profiler+Professional+software">Mass Profiler Professional (MPP) software</a><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_black_pepper_origin_7850_icp_ms_5994_8741en_agilent_7c190968ef.pdf">Full PDF for download</a></li></ul>Black pepper’s high value and global demand are drivers for economically motivated adulteration, a fraudulent practice that can pose public health risks. Because black pepper is most often sold in ground, crushed, or mixed forms, its supply chain is difficult to monitor and manage. Also, consumer campaigns against deforestation and the European Union Regulation on Deforestation-free (EUDR) products have increased calls for greater sourcing transparency. Products with a known geographical indication can demand a higher price. Companies do not want to become implicated in false claims about the sourcing of products, and many are keen to have full visibility of their products’ origin. To address this need, the European Commission has established the Protected Geographical Indication (PGI) system to protect regional specific products, thereby promoting their unique characteristics based on geographical origin and traditional competence of production. The PGI scheme has increased the demand for detailed information regarding the geographical source of food products, a trend that is likely to continue as EUDR is implemented across the EU and associated markets. Verifying the geographical origin of black pepper using elemental fingerprints is highly relevant to protecting value chain stakeholders, ensuring both quality and traceability while upholding the principles of food integrity.&nbsp;Several analytical methods can be used for profiling certain elements in foods. However, inductively coupled plasma mass spectrometry (ICP-MS) is unique because of its rapid throughput, multi-element capability, ultratrace sensitivity, isotopic analysis, versatility across sample types, low sample volume requirements, compliance with regulatory requirements, and low cost.3&nbsp;The Agilent 7850 ICP-MS is equipped with an Octopole Reaction System (ORS4 ), a collision/reaction cell (CRC) that uses helium (He) gas and Kinetic Energy Discrimination (KED) to remove polyatomic interferences on key analytes.4 If left unchecked, these interferences can affect data accuracy in complex food products. The integration of the 7850 with Agilent ICP-MS MassHunter software streamlines data analysis. When integrated with chemometric analysis, ICP-MS demonstrates high precision in multi-elemental profiling of diverse food matrices, effectively distinguishing their geographical origin.5&nbsp;In this study, 150 black pepper samples from five countries (Brazil, Cambodia, India, Indonesia, Vietnam) were analyzed using the 7850 ICP-MS to obtain elemental fingerprints of the samples. Agilent Mass Profiler Professional (MPP) software was used to process the ICP-MS elemental data and to construct chemometric models for distinguishing the geographical origin of the samples, as adapted from Chilaka et al.5<h4>Experimental&nbsp;</h4><h5>Instrumentation&nbsp;</h5>An <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?manufacturerItems=1&amp;search=7850+ICP-MS">Agilent 7850 single-quadrupole ICP-MS</a> was used for the analysis of 38 elements in the black pepper samples. Sample introduction was performed via a peristaltic pump connected to an Agilent MicroMist nebulizer and an Agilent SPS 4 autosampler. All elements were measured using helium collision (He KED) mode, except for boron (B), which was analyzed in no gas mode. Instrument control was performed using <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?manufacturerItems=1&amp;search=MassHunter">Agilent ICP-MS MassHunter 5.1 software</a>, and data processing was conducted using <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?manufacturerItems=1&amp;search=Mass+Profiler+Professional+software">Agilent MPP software</a>, version 15.1. Instrument operating conditions as shown in Table 1.<h4>Conclusion&nbsp;</h4>This study investigated the potential of ICP-MS elemental profiling coupled with chemometric analysis for geographical origin discrimination of black pepper samples from five countries, including Brazil, Cambodia, India, Indonesia, and Vietnam. A total of 38 elements was measured in 150 black pepper samples using the Agilent 7850 ICP-MS. Chemometric analysis was performed on the ICP-MS elemental data using Agilent Mass Profiler Professional (MPP) software. The PCA analysis exhibited satisfactory reliability and classification rates and demonstrated potential for the authentication of the geographical origin of black pepper. However, the separation of the Cambodian and Vietnamese samples was less distinct than the other groups, revealing potential similarities in elemental profiling between the bordering countries, which share similar climatic, geological, and agricultural conditions. Using LDA and RF classification models on the black pepper test set, we achieved a high overall accuracy in determining the geographical origin of the samples. These findings provide empirical support for the combined use of elementomics and chemometric techniques in black pepper authentication, contributing to fraud prevention. The study also demonstrates the potential of the method for application to other food types.<h3>2. Metrohm: Milk powder analysis by near-infrared spectroscopy</h3>Determination of moisture, fat, lactose, and protein content<ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_nir_128_download_867321cfb0.pdf">Full PDF for download</a></li></ul>For milk powder producers, final product control is essential to meet strict regulatory standards, guarantee comprehensive quality assurance, ensure consistent nutritional quality, and extend shelf life. These are all especially important for infant formula and dairy ingredients used in sensitive applications. Near-infrared spectroscopy (NIRS) is a fast, reagentfree method for measuring key quality parameters such as moisture, protein, lactose, and fat content directly in milk powder. The NIRS solution requires no sample preparation, enabling real-time monitoring either in the lab or directly on the production line. This allows producers to react quickly to process variations, minimize waste, and maintain product integrity batch after batch.<h4>EXPERIMENTAL EQUIPMENT&nbsp;</h4>More than 600 samples of powdered milk from different suppliers were analyzed on an <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?manufacturerItems=56&amp;search=OMNIS+NIR">OMNIS NIR Analyzer</a> (Figure 1). The different milk powders were placed into an OMNIS sample cup and analyzed in diffuse reflection mode. To include sample variety, the sample rotated during measurement to collect spectra from different locations. The automatically averaged spectra were used for model development. Reference values were obtained by official methods, e.g., AOAC 927.05 (moisture), AOAC 939.02 (protein), and AOAC 932.06 (fat). For the lactose content determination, a phenol-sulfuric acid method was used.<h4>CONCLUSION</h4>This Application Note presented the analysis of milk powder using NIR spectroscopy. Models for several quality parameters (fat, protein, lactose, and moisture content) were created. Independent validation samples confirmed the robustness and reliability of the models, with high correlation coefficients and low prediction errors achieved across all parameters. Notably, the dataset included samples from diverse global origins, capturing a broad range of product variability. This study shows that NIRS can be successfully integrated into the quality control workflow for dairy powder analysis.<h3>3. Shimadzu: Analysis of Electrolyte and Electrode in LIB Degraded by Overcharge and High Temperature</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_01064_en_b4f9f4330a.pdf">Full PDF for download</a></li></ul><h4>User Benefits</h4><ul><li>ICP-AES enables accurate quantification of cathode material dissolved in electrolytes.</li><li>GC-MS assesses degradation from components in electrolytes with unknown usage.</li><li>EDXRF easily evaluates transition metals, phosphorus, fluorine, and other elements deposited on electrodes</li></ul>When lithium-ion batteries are used in EVs or ESS applications, numerous cells are connected in series and parallel to form modules, and multiple modules are further connected to construct a pack. In such configurations—where many cells are connected in series—the state of charge of individual cells varies, as shown in Figure 1. Moreover, because the cells are densely packed to reduce volume, the ambient temperature experienced by each cell also varies. In this application, we conducted cycle tests under overcharged or high-temperature conditions, disassembled the degraded pouch cells, and analyzed both the electrolytes and the electrodes.<h4>Analysis of electrolyte and electrode</h4>Electrolytes and electrodes were extracted from the batteries degraded through the cycle tests (hereafter referred to as “degraded cells”) and analyzed using the instruments shown in Figures 3–5. It is known that electrolytesin degraded cells contain transition metals (Ni, Co, Mn) dissolved from the cathode active material1). In addition, electrolyte solvents are known to generate characteristic degradation products as deterioration progresses2). By analyzing these degradation-related elements and compounds, the degradation state of the battery can be assessed. In this article, we propose a multifaceted evaluation of electrolytes using <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?manufacturerItems=3&amp;search=ICPE-9820">ICP-AES</a> and GC-MS. On both the cathode and anode, insulating layers known as CEI/SEI form on the electrode surfaces. Under improper charging conditions, excessive formation of these layers can lead to capacity loss. Furthermore, the dissolved metals from the cathode deposit and precipitate on the anode. These deposits can cause internal short circuits, posing risks such as fire hazards. While such electrode conditions are typically evaluated by ICP-AES or XPS to examine elemental content or surface chemical states, this article introduces a simpler evaluation method using <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?manufacturerItems=3&amp;search=EDX-8100">EDXRF</a>.<h4>Summary</h4>Analysis of the electrolytesfrom degraded batteries using ICP-AES and GC-MS revealed dissolution of transition metals as well as the formation of degradation products. Furthermore, EDXRF analysis of the electrodes enabled straightforward detection of changesin elemental composition, including transition metals, fluorine, and phosphorus. These analytical techniques allow for a multifaceted evaluation of battery degradation. In real-world battery operation, fluctuations in charging conditions and ambient temperature introduce variability in degradation states. By assessing degradation mechanisms individually, as demonstrated in thisreport, it is possible to obtain insights that contribute not only to improving intrinsic battery performance but also to optimizing implementation methods and control conditions.<h3>4. Thermo Fisher Scientific: Analyzing Spinel refractory MgO-Al2O3 premix using <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?manufacturerItems=2&amp;search=ARL%E2%84%A2+X%E2%80%99TRA+Companion">ARL X’TRA Companion XRD</a></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/spinel_refractory_xrd_an41525_en_75f2527e78.pdf">Full PDF for download</a></li></ul>Spinel refractories—primarily magnesia–alumina (MgAl₂O₄)— are the workhorses of high-temperature linings in steel ladles, cement rotary kilns, glass tanks, and non-ferrous smelters. Their appeal lies in a combination of shock resistance, chemical stability against basic slags, and an expansion behavior that mitigates cracking. Depending on the duty, they are used as bricks, castables, or gunned repairs, sometimes with engineered microstructures that blend spinel with periclase, corundum, or zirconia to tune creep, corrosion, and spalling performance.&nbsp;X-ray diffraction (XRD) underpins manufacturing control from raw mix to fired product. During synthesis, XRD tracks the solid-state reaction of MgO and Al₂O₃ into spinel, verifying the disappearance of periclase and alumina and quantifying the spinel fraction by Rietveld analysis. Lattice parameters reveal cation stoichiometry and solid-solution effects; peak breadth trends indicate crystallite growth and microstrain, proxies for sintering progress. In finished components, XRD detects secondary phases such as calcium aluminates introduced by binders, slags, impurities, and it provides fingerprinting for batch-to-batch consistency after thermal exposure. Embedded into routine QA/QC, XRD shortens feedback loops, stabilizes recipes, and links processing conditions to the microstructure that governs refractory life.<h4>Instrument &amp; software&nbsp;</h4>The <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?manufacturerItems=2&amp;search=ARL%E2%84%A2+X%E2%80%99TRA+Companion">Thermo Scientific™ ARL™ X’TRA Companion</a> X-Ray Diffractometer (c.f. Figure 1) is a simple, easy-to-use benchtop instrument for routine phase analysis as well as more advanced applications. The ARL X’TRA Companion uses a θ/θ goniometer (160 mm radius) in Bragg-Brentano geometry coupled with a 600 W X-ray source (Cu or Co). The radial and axial collimation of the beam is controlled by divergence and Soller slits, while air scattering is reduced by a variable beam knife. An integrated water chiller is available as an option. Thanks to the state-of-the art solid state pixel detector (55x55 μm pitch), the ARL X’TRA Companion provides very fast data collection and comes with single-click Rietveld quantification capabilities and automated result transmission to a LIMS (Laboratory Information Management System) seamless integrated into Thermo Scientific™ SolstiX™ Pronto instrument control software.<h4>Your benefits&nbsp;</h4>The ARL X’TRA Companion XRD workflow delivers answers in minutes, quantifying MgO, α-Al₂O₃, and MgAl₂O₄ while resolving Ca–Si silicates and trace Fe-spinels. Subtle differences between corundum and spinel are cleanly separated, and LOI drivers—carbonates, brucite, and Mg-sulfates—are identified and trended. These insights let you compute spinel potential, anticipate pore-closing expansion, and set the right pre-dry / prefire schedule to avoid spalling. You can clearly distinguish mid-grade, ore-derived feeds from premium low-silica materials, tighten incoming QA, and optimize formulations for cement/lime kilns, tundish linings, and other carbon-free basic applications.

News from LabRulezICPMS Library - Week 07, 2026

Although modern agriculture needs to be based on accurate real-time data on soil, plant, and environmental conditions, affordable, sufficiently sensitive, and robust monitoring devices for this purpose are currently missing. According to scientists, low-cost sensors based on new smart materials and printing technologies offer a suitable solution. The results of multidisciplinary research thus far and proposals for the development of these devices have been presented by researchers from Czechia, Great Britain, Spain, and the USA in a review article in the prestigious journal <a target="_blank" rel="noopener noreferrer" href="https://www.nature.com/articles/s41467-026-68778-6#Abs1">Nature Communications</a>.“Sensor technologies for monitoring plant health are still in their infancy. Only simple sensors capable of monitoring basic parameters such as pH, soil moisture, or temperature are commonly available on the market. However, if farmers are to face current challenges, including climate change, and ensure sufficient food for humanity, they need much more effective tools that will enable them to monitor, for example, various pathogens, including bacteria and fungi. In our opinion, a suitable solution is a combination of new smart materials and printing for the production of inexpensive, durable, and scalable materials,” said the article’s first author, David Panáček from CATRIN, who worked on the study during his internship at Imperial College London.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CATRIN_Soucasne_senzory_nestaci_Vedci_navrhuji_novou_cestu_ke_sledovani_zdravi_rostlin_b4014952a3.jpg" alt="CATRIN: David Panáček" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CATRIN_Soucasne_senzory_nestaci_Vedci_navrhuji_novou_cestu_ke_sledovani_zdravi_rostlin_b4014952a3.jpg 208w," sizes="100vw" width="1536" height="1152">Sensors for monitoring plant health, for example, lag behind similar devices used in human medicine. According to the authors, advances in materials science, which will enable the development of scalable sensor technologies, play a key role in this potential shift. “Printing techniques, including inkjet printing, screen printing, aerosol printing, 3D printing, and direct laser writing, offer flexible ways to produce flexible sensors, large-area sensors, and sensors integrated directly into plants. The review article summarizes recent advances in printable low-dimensional materials for agricultural sensors, analyzes their physico-chemical properties in relation to sensor performance, and discusses key challenges and future opportunities requiring interdisciplinary integration,” said one of the corresponding authors, Michal Otyepka.The research brought together materials scientists, chemists, biologists, sensing experts, and printing technology specialists. Materials research and the use of graphene-based smart materials were led by scientists from CATRIN at Palacký University and VŠB-Technical University of Ostrava. Plant biologists from CATRIN contributed their knowledge of plant development, their responses to stress conditions, and the monitoring of their properties. Researchers from Imperial College London took care of the electronics, while representatives from<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/36"> CEITEC – VUT</a> focused on printing technologies. The team also included leading experts in sensing from the Catalan Institute of Nanoscience and Nanotechnology in Barcelona, and Joseph Wang of the University of California San Diego, the “father of sensing and electrochemistry,” also contributed his extensive knowledge.“This is a groundbreaking study on this topic, which has managed to attract some truly big names in their respective fields. Last but not least, the study demonstrates that interdisciplinarity at CATRIN gives rise to completely new and promising research topics, such as plant sensing and its use for studying plant-environment interactions and smart agriculture,” added another corresponding author, Nuria De Diego.

Current sensors are not good enough. Scientists propose a new way to monitor plant health

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Eurachem is a European network promoting international traceability of chemical measurements and good analytical practice. It provides expert guidance, supports method validation, uncertainty evaluation, proficiency testing, and facilitates discussion on technical and policy issues in analytical quality.

Eurachem

The Czech Advanced Technology and Research Institute (CATRIN) at Palacký University is a cutting-edge scientific hub dedicated to advancing research in the fields of nanotechnology, biotechnology, and biomedicine. At its core, CATRIN boasts outstanding scientific teams, featuring international researchers. We emphasize interdisciplinarity, foster global collaborations, and work to translate our research findings into practical applications.

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Bruker

Once again, we point out the strong synergies of pharmaceutical research, process development and quality control with Raman microscopy. In this webinar, our Raman expert Di Yan will first highlight the basics and then analyze three typical samples. For this, we leave the "PowerPoint monotony" and go hands-on with the Raman microscope. Afterwards there will be a live question and answer session to answer your questions.You will learn about:<ul><li>How to apply Raman microscopy</li><li>What to look out for in Raman instrumentation</li><li>How to comply with regulations using a Raman microscope</li></ul>What is the goal of the webinar:<ul><li>Demonstrate the utility of Raman microscopy in Pharma</li><li>Highlight the unique benefits of Raman microscopy</li></ul>We will discuss:<ul><li>Relationships between Raman and other techniques (e.g. XRD)</li><li>Basics of Raman microscopy and imaging</li><li>Application example #1: API distribution</li><li>Application example #2: Polymorphism</li><li>Application example #3: Particle analysis</li></ul>Who should attend:<ul><li>R&amp;D specialists, especially process developers</li><li>Quality control and PAT specialists</li><li>Planning to buy Raman microscope</li><li>Thinking about implementing Raman microscopy</li><li>Want to learn more about Raman microscopy in Pharma</li></ul><blockquote>Presenter: Dr. Di YanDr. Di Yan is a product manager at Bruker for Raman microscopy. He has studied physical chemistry at Friedrich Schiller University and Leibniz Institute of Photonic Technology and has extensive experience in Raman detection techniques.</blockquote>

Bruker: Tools for Pharmaceutical Troubleshooting: Raman Microscopy

Tools for Pharmaceutical Troubleshooting: Raman Microscopy

In this webinar, our Raman expert Di Yan will first highlight the basics and then analyze three typical samples.

By combining infrared spectroscopy with atomic force microscopy (AFM-IR), it is possible to perform chemical analysis and compositional mapping with a spatial resolution down to 10 nm, which greatly surpasses standard optical diffraction limits. During this 2-hour event, our speakers explore:<ul><li>Origins of the AFM-IR technique</li><li>Recent advances in AFM-IR technology</li><li>Applications that can benefit from AFM-IR spectroscopy—especially life sciences and environmental chemistry</li></ul>Bruker Application Scientist Dr. Cassandra Phillips hosts the workshop and live demos, providing an overview of Bruker's latest nanoIR product updates.&nbsp;Watch this webinar to:<ul><li>Hear distinguished guest speakers discuss their work on AFM-IR with the nano-IR platform</li><li>Experience Bruker's new patented Surface Sensitive mode</li><li>Become familiar with Bruker's new AFM-IR platforms</li></ul><blockquote>Presenter: Xiaoji Xu, Ph.D.Presentation: NanoIR through PeakForce Infrared (PFIR) MicroscopyHere, Xiaoji Xu, Ph.D. (Lehigh University) introduces the novel PFIR method of AFM-IR developed at Lehigh University. This method of label-free chemical nanoscopy is based on the mechanical detection of photothermal response by AFM operated in PeakForce Tapping mode and ultimately can achieve a higher spatial resolution (sub-10 nm) and provide more rich chemical information than many of the existing tools we use for chemical imaging—or imaging in general—while also providing greater flexibility in applicability to samples in both air and liquid.In addition to providing a review of the strengths and benefits of PFIR as they relate to foundational AFM-IR and PeakForce Tapping principles and capabilities, the presentater explores and provides detailed, real-world examples of PFIR's applicability to a broad range of sample types and experimental settings.Presenter: Dmitry Kurouski, Ph.D.Presentation: Biology at the Nanoscale: From Viruses to AmyloidsIn this presentation, Dmitry Kurouski, Ph.D. (Texas A&amp;M University) showcases his team's research and findings using TERS and AFM-IR to investigate viruses, viral particles, and alpha-synuclein oligomers. Topics of this discussion range from an exploration of how IR/AFMIR spectroscopy reveals a variety of infrared spectra in biological samples that are otherwise inaccessible by traditional Raman microscopy methods, to a detailed presentation of the team's findings via a combination of AFM-IR and TERS about changes observed in the secondary structural organization and surface structure information of populations of oligomers relative to their impact on the development of Parkinson's disease.These two technologies possess different capabilities that demonstrate strong complementarity in terms of both the chemical information available and the achievable probing depth.Presenter: Cassandra Philips, Ph.D.Presentation: Quantitative Demonstration of Surface Sensitivity with nanoIR3The presenter conducts a profile analysis of a PMMA wedge sample in both Resonance enhanced and Surface Sensitivity modes, then demonstrate the analytical process for data collected in Surface Sensitivity mode.Comparison of the data outputs of various operational modes demonstrates that using the same probe and sample, users can switch from looking at bulk measurements (where the signal increases linearly with the thickness) to measurements with a surface sensitivity on the order of 15 nm just by adjusting the parameters.Surface Sensitivity mode enables measurement of the top layer of a sample with significantly improved accuracy over other operational modes, as it collects data only from the surface and not from the absorbing material beneath it.&nbsp;Presentation: Demonstration: New Platforms for AFM-IRThe presenter introduces the unique capabilities of a new Bruker platform for AFM-IR imaging.Looking at a sample of PMMA beads in epoxy resin, the presenter demonstrates the new platform's capability to achieve higher acuity and operate at higher scan speeds than other nanoIR systems. Its integration with both Bruker's most advanced AFM controller and legacy Tapping Mode imaging capabilities are explored.Additionally, the presenter showcases the ability to switch wavenumber and reconfigure laser power mid-scan (to look at both the epoxy band and the carbonyl band of the sample), as well as the platform's unique capacity to switch between sample-scanning and tip-scanning configurations, enabling investigation of the chemical composition and mechanical properties of the same sample using the same probe.</blockquote>

Bruker: NanoIR Spectroscopy & Imaging: Recent Developments and Applications

NanoIR Spectroscopy & Imaging: Recent Developments and Applications

Find out more about Bruker's latest nano IR product updates and see real-time demonstrations of the new Surface Sensitive mode and new AFM-IR platforms

NanoIR Spectroscopy & Imaging - Developments & Applications

Attend our on-demand webinar: „The True Value of FT-IR and Raman as a Quality Control Tool in Pharmaceutical Manufacturing“

Bruker: The True Value of FT-IR and Raman as a Quality Control Tool in Pharmaceutical Manufacturing

The True Value of FT-IR and Raman as a Quality Control Tool in Pharmaceutical Manufacturing

Attend our on-demand webinar about the True Value of FT-IR and Raman as a Quality Control Tool in Pharmaceutical Manufacturing.

FT-IR and Raman in Pharmaceutical Manufacturing

We collected real-life applications of particle analysis in pharmaceutical manufacturing and quality control and present them in this brief 20 minute webinar.Learn about the differences of FT-IR and Raman microscopy in particle analysis and which technique is the best for a specific scenario.

Bruker: Root Cause, Particle and Failure Analysis in Pharmaceutical Industries

Root Cause, Particle and Failure Analysis in Pharmaceutical Industries

Learn about the differences of FT-IR and Raman microscopy in particle analysis and which technique is the best for a specific scenario.

Particle Analysis in Pharmaceutical Industries

Biogen is among the first biopharmaceutical companies to employ PAT in an active role in the manufacturing of biologicals. The implementation of in-process Raman for glucose control, biocapacitance for in-line cell growth monitoring as well as in-line refractive index and other univariate techniques for the automatic in-line release of process solutions is being discussed. GMP-specific considerations such as risk assessment, data integrity and qualification strategy are presented as well.The application of PAT in an active role as part of the control strategy in commercial production in a cGMP compliant environment is not yet done very frequently in the biopharmaceutical industry. This is due to a combination of risk factors which typically involve regulatory challenges, technology maturity and economic benefit. Biogen decided to employ PAT at large scale mammalian cell culture at its new manufacturing site at Solothurn, Switzerland. Biogen’s Aducanumab process has shown to benefit significantly from direct PAT control. Inline Raman spectroscopy and inline biocapacitance are used to actively control the feed of glucose and nutrients to the production bioreactor. The glucose concentration is predicted using a validated PLS model and is used as input for a closed loop control device that is controlling the addition of glucose solution to the bioreactor in a virtually continuous manner.<blockquote>Presenter: Oliver Steinhof (Global Lead PAT, Biogen)Supporting the Digital Development and Analytics team at Biogen since 2017 with a focus on PAT implementation and commercialization. Focus over the last 4 years was the startup of Biogen’s Next Generation Manufacturing facility at Solothurn Switzerland. Since 2015 at Lonza Visp, Switzerland, leading the PAT laboratory and providing PAT consulting and solutions to the global Lonza network, including small molecule API manufacture and chemicals. Since 2009 several roles at Shell Global Solutions in Hamburg Germany around lubricants R&amp;D, including management of the analytical services team, global technical support manager, internal consultant, quality auditor and project leader for R&amp;D projects. Chemist by training, spending time at the Universities of Braunschweig Germany, Salt Lake City Utah and Tuscaloosa Alabama. PhD in industrial chemistry sponsored by BASF SE with a focus on on-line NMR spectroscopy and reaction engineering of complex polycondensations.Presenter: Martin Gadsby (Owner and Director, Optimal Industrial Automation)Martin graduated from the University of Bath in the late 1970’s, and after working through a few positions in industry, he became the European R&amp;D Process and Process Automation Group Leader for Kraft Foods. &nbsp;After a few years at Kraft, Martin decided to set up a process automation business with a colleague, Dave Richards, and Optimal was born. Optimal Industrial Automation was formed over 33 years ago, with Martin now being the Vice President of Optimal Industrial Technologies which was formed more recently as the products division and is the market leader in the field of Process Analytical Technology (PAT) with its PAT Knowledge Management product – synTQ. &nbsp;Martin is intimately involved with progressing the evolution of synTQ and advising the Optimal development team on what he believes to be the optimum development direction. &nbsp;Over the last few years, he has taken on the overall responsibility not only for the company but also for the sales and marketing of synTQ whilst remaining very active in ensuring that the development of synTQ continues unabated. &nbsp;On the personal front, Martin is a bit of a ‘petrol head’ and enjoys flying aerobatics and racing cars.</blockquote>

Bruker: Next Generation Manufacturing at Biogen – PAT as an Enabler for Enhanced Process

Next Generation Manufacturing at Biogen – PAT as an Enabler for Enhanced Process

In this webinar, the implementation of in-process Raman for glucose control is being discussed.

Biogen – PAT as an Enabler for Enhanced Process

The polymer industry is one of the world’s largest industrial sectors. &nbsp;Almost all consumer products are composed of polymers of some sort. &nbsp;These products range across items like automobiles, pharmaceuticals, toys, packaging, computer and cell phones, and so on. &nbsp;There are a few areas where characterizing these polymer-based objects can be important: first is performing a quick polymer identification for recycling purposes; second is quality control to identify product defects or failures; and third is reverse engineering to facilitate product development in a highly competitive marketplace. &nbsp;Vibrational spectroscopy (infrared (IR) and Raman) is especially useful for the analysis of polymers in an industrial setting. &nbsp;IR and Raman are highly specific and sensitive tools that are non-destructive and easy to use. &nbsp;Examples will be presented demonstrating the effectiveness of IR and Raman analysis in each of these categories.Mass Spectrometry (MS) has become an indispensable tool for polymer analysis and has been widely used to study polymer structure and composition, end-groups and additives, molecular weight distribution, and so on. &nbsp;MS analysis is extremally sensitive, allowing the detection and identification of minor polymer components and synthesis by-products, as well as low-level impurities and products of decomposition. &nbsp;Matrix Assisted Laser Desorption Ionization (MALDI) allows to perform rapid MS analysis without lengthy pre-separation and with minimal sample preparation. &nbsp;MALDI MS can provide structural and copolymer composition information, as well as be used for imaging of polymer surfaces, characterization of complex polymer mixtures and many other analytical tasks. &nbsp;In this webinar, we will discuss several MS analytical techniques and their applications for polymer analysis using real life examples from the industry and academia.<blockquote>Presenter: Dr. Tom Tague (Applications Manager and Chair of the Safety Committee Bruker Corporation)Dr. Tom Tague is the Applications Manager (FTIR and Raman products) and Chair of the Safety Committee for Bruker Corporation. He is also a member of the Visiting Advisory Committee of the Metropolitan Museum of Art in New York and the Advisory Board of Amplified Sciences. Dr. Tague received his Ph.D. from the University of Utah in Physical Chemistry and his B.S. in Chemistry, from the University of Texas at San Antonio. He conducted his postdoctoral research at the University of Virginia working with professor Lester Andrews. He is a member of the American Chemical Society, the Society for Applied Spectroscopy, the American Physical Society, and the Optical Society of America. Dr. Tague is active in developing new methods and instrumentation with the goal of improving the sensitivity and detection limits of spectroscopy related applications. Dr. Tague has more than 80 publications and 5 patents.Presenter:&nbsp;Dr. Artem FilipenkoDr. Artem Filipenko has over 15 years of industry experience in development of innovative methods and instrumentation for various analytical applications, including food, environmental, industrial, and homeland security. His area of professional expertise ranges from Ion Mobility, Mass Spectrometry, and Gamma Spectroscopy to molecular and nuclear physics. Artem holds a doctorate degree in molecular physics and master’s degree in microelectronics from the National Nuclear Research University in Moscow, as well as master’s degree in business administration from Babson College in Boston.</blockquote>

Bruker: Effectively Analyzing Polymers Using IR, Raman Spectroscopy and MALDI-TOF Mass Spectrometry

Effectively Analyzing Polymers Using IR, Raman Spectroscopy and MALDI-TOF Mass Spectrometry

In this webinar, we will discuss several MS analytical techniques, IR and Raman and their applications for polymer analysis 

Analyzing Polymers by IR, Raman Spectroscopy and MALDI-TOF

FT-IR is a commonly employed technique in the lab due to the vast array of analytical opportunities it offers. However, carrying out FT-IR spectroscopy is not the most intuitive process using current technology.With the release of LUMOS II, Bruker extends the scope of FT-IR microscopy and imaging for applications and increases its accessibility for all users. It is a faster, smarter imaging solution designed for daily use in routine and research laboratories, regardless of user skill level.Bruker’s specialist for FT-IR and Raman microscopy, Dr. Thomas Tague, will present its key hardware and software features and discuss the benefits of automation and focal-plane array imaging. The application of these novel capabilities to the polymer, pharmaceutical, and material science industries will also be shown.What This Webinar Covers:<ul><li>LUMOS II and its software OPUS</li><li>Technical features and workflow</li><li>FT-IR microscopy and imaging</li><li>Focal-plane array detectors</li><li>Applications of µ-FT-IR</li></ul>It Is Intended for Analytical Professionals in:<ul><li>QA/QC</li><li>Production</li><li>Manufacturing</li><li>Operations</li><li>Research &amp; Development</li></ul>With the Job Roles of:<ul><li>Lab Manager</li><li>QC Manager</li><li>Analytical Scientist</li><li>Researcher</li></ul>

FT-IR Imaging Webinar | LUMOS II

In this webinar, Bruker introduce LUMOS II which extends the scope of FT-IR microscopy and imaging 

FT-IR Imaging Webinar - LUMOS II

Vibrational microscopy is an established technique for materials identification and characterization which finds extensive applications in various fields including but not limited to pharmaceuticals, polymers, forensics, cultural heritage, life science, mineralogy, materials science and more.<blockquote>Presenter: Dr. Sergey Shilov (North America Product Manager, Science Business Unit, Bruker Optics)Dr. Sergey V. Shilov is a Product Manager for North America at Bruker Optics. Sergey joined Bruker in 2001. He is responsible for the support and development of new applications for the Bruker research FTIR systems. He received his Ph.D. in 1992 from the Russian Academy of Sciences in Polymer Physics and his M.S. from St. Petersburg State University (Russia) in Physics in 1986. Alexander Von Humboldt Foundation (Germany) awarded him a research fellowship in 1996. Sergey published 37 papers in peer-reviewed journals. His research interests include time-resolved FTIR spectroscopy, surface science, polymer, and life-science applications.&nbsp;</blockquote>

Bruker: State-of-the-Art Microanalysis Using Infrared and Raman Microscopy

State-of-the-Art Microanalysis Using Infrared and Raman Microscopy

In this webinar, participants will learn about the state-of-the art microanalysis using IR and Raman Microscopy.

State-of-the-Art Microanalysis Using IR and Raman Microscopy

The achievable spatial resolution in Raman microscopy is ultimately limited by physical laws (diffraction of light). We revisit the physical principles and try to reach the limits of Bruker’s Raman microscope.<blockquote>Presenter: Dr. Marten SeebaDr. Marten Seeba graduated in chemistry from the University of Göttingen before joining Bruker as an application expert for FT-IR and IR laser microscopy. He is a point of contact for our customers and as such has gained a great deal of expertise in many applications such as microplastics, pharmaceuticals, tissue analysis and materials science.</blockquote>

Bruker: Raman Microscopy – Spatial Resolution and Light Diffraction – SENTERRA II

Raman Microscopy – Spatial Resolution and Light Diffraction – SENTERRA II

In this webinar, we revisit the physical principles of Raman Microscopy and try to reach the limits of Bruker’s Raman microscope.

Raman Microscopy – SENTERRA II

The role of the modern QA/QC laboratory has evolved into one where problems of almost any type are encountered. Product analysis is conducted using a variety of scientific instrumentation, some destructive and some not. Specificity and sensitivity are key elements of any analytical tool to be employed in this environment.&nbsp;In this webcast, we will discuss the role Raman micro- and macro-spectroscopy can play in simplifying and streamlining the analysis of products and packaging will be discussed. Additionally, the usefulness of Raman spectroscopy will be reviewed for the identification of product defects due to foreign body inclusions, content defects, or deviations from expected content uniformity.&nbsp;Specific topics we will cover include:<ul><li>Raman and regulatory compliance</li><li>Where does Raman fit in the QA/QC laboratory?</li><li>Characterizing unknown foreign bodies in product</li><li>Assessing product quality assurance quickly and easily</li></ul>Key Learning Objectives<ul><li>Learn how Raman spectroscopy can be seamlessly added to your compliant QA/QC laboratory</li><li>Learn the value of Raman for identifying unknown objects non-invasively</li><li>Learn how content uniformity and component distribution can be readily characterized</li></ul>Who Should Attend?<ul><li>QA/QC analyst in polymers, pharmaceutical, forensic, and materials–based industries</li></ul><blockquote>Presenter: Dr. Tom Tague (Applications Manager and Chair of the Safety Committee Bruker Corporation)Dr. Tom Tague is the Applications Manager (FTIR and Raman products) and Chair of the Safety Committee for Bruker Corporation. He is also a member of the Visiting Advisory Committee of the Metropolitan Museum of Art in New York and the Advisory Board of Amplified Sciences. Dr. Tague received his Ph.D. from the University of Utah in Physical Chemistry and his B.S. in Chemistry, from the University of Texas at San Antonio. He conducted his postdoctoral research at the University of Virginia working with professor Lester Andrews. He is a member of the American Chemical Society, the Society for Applied Spectroscopy, the American Physical Society, and the Optical Society of America. Dr. Tague is active in developing new methods and instrumentation with the goal of improving the sensitivity and detection limits of spectroscopy related applications. Dr. Tague has more than 80 publications and 5 patents.</blockquote>

The Role of Raman Spectroscopy in the QA/QC Laboratory