<p><strong>Jiří Nováček, a researcher and the deputy director for research infrastructure at CEITEC Masaryk University, shares insights into his journey with Brnoregion Microscopy. Sparked by a conversation with Jan Neuman, Nováček saw the potential of integrating Atomic Force Microscopy (AFM) into life-science electron microscopy. Today, he plays an active role in the community, collaborating with colleagues to enhance educational initiatives.&nbsp;</strong></p><h4><strong>How did you become involved with Brnoregion Microscopy?</strong></h4><p>My involvement with Brnoregion Microscopy began through my interaction with <a target="_blank" rel="noopener noreferrer" href="https://brnoregion.com/en/news/people-of-brnoregion-microscopy-jan-neuman-nenovis">Jan Neuman</a>. We were discussing the potential applications of their integrated Atomic Force Microscopy (AFM) module in the field of life-science electron microscopy. I was immediately intrigued by the idea of forming a microscopy community and saw great potential in it. Jan's vision of fostering stronger local connections among colleagues with complementary expertise resonated with me. This alignment of interests and the shared goal of advancing our understanding and capabilities in microscopy made me eager to join and contribute to the community.&nbsp;</p><h4><strong>What role do you play in the community?</strong></h4><p>Currently, I am an active member of the Community working group within Brnoregion Microscopy. In this role, I collaborate closely with Tomáš Vystavěl from Thermo Fischer Scientific on various educational initiatives. Our focus is on enhancing the educational aspects of the Microscopy community, looking for opportunities for deepening the knowledge and skills in the area of microscopy in our region. It's a rewarding experience to be part of a team that is dedicated to fostering learning and innovation in this field.&nbsp;</p><h4><strong>What benefits does it bring to you?</strong></h4><p>Being part of the Microscopy community has been incredibly enriching for me. It provides a platform for continuous learning and exposure to the latest advancements in microscopy technology and techniques. Working together stimulates new ideas and approaches, which are key to our ongoing development. Additionally, it offers the opportunity to network with experts and peers, opening doors to potential collaborations and projects. That’s how it works in our local innovation ecosystem… &nbsp;</p><h4><strong>Do you have any message for the community?</strong></h4><p>Whether you're already involved or just curious, join the upcoming <a target="_blank" rel="noopener noreferrer" href="https://brnoregion.com/en/events/120-seconds-meet-brnoregion-microscopy-24-11">120 seconds: Meet Brnoregion Microscopy</a> event. It's a fantastic opportunity to see first-hand how the Microscopy community can benefit you. These events are designed to showcase the practical applications of microscopy and the innovative work being done by our members.&nbsp;</p>

People of Brnoregion Microscopy: Jiří Nováček (CEITEC MUNI)

<p><strong>In the week from January 20, the following webinars await you in the field of atomic and molecular spectroscopy and spectrometry</strong></p><blockquote><p><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></p><p><strong>👉 Search and filter in the largest global database</strong> with over <strong>4 000 GC, LC, MS and spectroscopy webinars</strong>.</p></blockquote><h5><strong>1. Anton Paar: Fundamentals of Scratch</strong></h5><div><div><ul><li><div>Tu, 21.1.2025 20:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/4449">Registration</a></div></li></ul></div><p>This webinar provides a thorough introduction to the theory and practice of instrumented scratch testing, a critical method for evaluating the mechanical properties of materials under stress.</p></div><h5><strong>2.&nbsp;Mettler-Toledo: Advanced Inspection of Canned Goods with X-ray Inspection</strong></h5><div><div><ul><li><div>We, 22.1.2025 09:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/4658">Registration</a></div></li></ul></div><p>Join our webinar to discover the wide range of benefits that x-ray inspection offers canned applications - including advanced detection capabilities and integrity and completeness checks.</p></div><h5><strong>3.&nbsp;Bruker: Nanoscale Chemical Characterization of Semiconductor Materials and Devices using Photothermal AFM-IR</strong></h5><div><div><ul><li><div>We, 22.1.2025 17:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/4681">Registration</a></div></li></ul></div><p>In this webinar, Bruker nanoscale IR spectroscopy experts show how photothermal AFM-IR can identify the local chemistry of defects.</p></div><h5><strong>4.&nbsp;Agilent Technologies: Using LDIR for Advanced Microplastics Characterization</strong></h5><div><div><ul><li><div>Th, 23.1.2025 09:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/4683">Registration</a></div></li></ul></div><p>This session will highlight the advanced features of LDIR technology and its critical applications in analyzing microplastics within various matrices.</p></div><h5><strong>5.&nbsp;LECO: Optimization of Combustion Methods for Determination of Low-Level Nitrogen-Protein in Food</strong></h5><div><div><ul><li><div>Th, 23.1.2025 16:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/4686">Registration</a></div></li></ul></div><p>In this webinar, Lloyd Allen, Ph.D., LECO's Director of the Technical Services Laboratory, will share practical insights on overcoming challenges using advanced combustion instruments.</p></div><h5><strong>6.&nbsp;Agilent Technologies: Different Cones / Nebulizers / Sample Introduction Systems .. Where and When to Use them</strong></h5><div><div><ul><li><div>Th, 23.1.2025 20:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/4546">Registration</a></div></li></ul></div><p>Different Cones / Nebulizers / Sample Introduction Systems .. Where and When to Use them</p></div>

Webinars LabRulezICPMS Week 4/2025

<p><strong>The goal of this study is to advance molecular epidemiology by integrating and analyzing large-scale population data from two complementary platforms: quantitative NMR spectroscopy for 209 lipoprotein measures and LC-MS/MS for 809 lipid classes and species. Together, these datasets encompass 1018 molecular measures across 7830 participants from two population cohorts. The study aims to elucidate the molecular and compositional relationships within the circulatory lipid transport system and their connections to physiological and clinical characteristics.</strong></p><p>Through cluster analyses and unsupervised neural network techniques (self-organizing maps), the study identifies inherent links between deep molecular data and population health traits, including cardiometabolic risk factors such as lipoprotein lipids, apolipoprotein B, ceramides, and oxidized lipids. Notable findings include the consistent cardiometabolic risk associations of triglyceride species across the lipoprotein cascade and the intricate metabolic profiles of cholesteryl ester species, which vary in their risk implications. This work highlights the unprecedented detail and compatibility of combined omics methodologies, paving the way for comprehensive molecular insights and new opportunities in large-scale population health studies.</p><blockquote><h4><strong>The original article</strong></h4><h4><a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.analchem.4c03229"><strong>Personalized Profiling of Lipoprotein and Lipid Metabolism Based on 1018 Measures from Combined Quantitative NMR and LC-MS/MS Platforms</strong></a></h4><p>Siyu Zhao, Corey Giles, Kevin Huynh, Johannes Kettunen, Marjo-Riitta Järvelin, Mika Kähönen, Jorma Viikari, Terho Lehtimäki, Olli T. Raitakari, Peter J. Meikle, Ville-Petteri Mäkinen, Mika Ala-Korpela</p><p>Analytical Chemistry, Vol 96/Issue 52</p><p><a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.analchem.4c03229">https://doi.org/10.1021/acs.analchem.4c03229</a></p><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/"><strong>CC-BY 4.0</strong></a></h6></blockquote><p>&nbsp;</p><p class="cke-user_style-important"><strong>Selected sections from the article follow. Formats and hyperlinks were adapted from the original.</strong></p><h3><strong>Abstract</strong></h3><p>Applications of advanced omics methodologies are increasingly popular in biomedicine. However, large-scale studies aiming at clinical translation are typically siloed to single technologies. Here, we present the first comprehensive large-scale population data combining 209 lipoprotein measures from a quantitative NMR spectroscopy platform and 809 lipid classes and species from a quantitative LC-MS/MS platform. These data with 1018 molecular measures were analyzed in two population cohorts totaling 7830 participants. The association and cluster analyses revealed excellent coherence between the methodologically independent data domains and confirmed their quantitative compatibility and suitability for large-scale studies. The analyses elucidated the detailed molecular characteristics of the heterogeneous circulatory macromolecular lipid transport system and the underlying structural and compositional relationships. Unsupervised neural network analysis─the so-called self-organizing maps (SOMs)─revealed that these deep molecular and metabolic data are inherently related to key physiological and clinical population characteristics. The data-driven population subgroups uncovered marked differences in the population distribution of multiple cardiometabolic risk factors. These include, e.g., multiple lipoprotein lipids, apolipoprotein B, ceramides, and oxidized lipids. All 79 structurally unique triglyceride species showed similar associations over the entire lipoprotein cascade and indicated systematically increased risk for carotid intima media thickening and other atherosclerosis risk factors, including obesity and inflammation. The metabolic attributes for 27 individual cholesteryl ester species, which formed six distinct clusters, were more intricate with associations both with higher─e.g., CE(16:1)─and lower─e.g., CE(20:4)─cardiometabolic risk. The molecular details provided by these combined data are unprecedented for molecular epidemiology and demonstrate a new potential avenue for population studies.</p><p>Lipoprotein lipids have had a central role in clinical risk assessment for cardiometabolic diseases since the 1950s. <a href="javascript:void(0);" aria-label="reference 1">(1)</a> The realization that <sup>1</sup>H NMR spectroscopy would be inherently suited for lipoprotein analytics took place in the early 1990s. <a href="javascript:void(0);" aria-label="reference 2">(2)</a> In addition to the fundamental advantages of <sup>1</sup>H NMR spectroscopy in producing quantitative data, the spherical monolayered structure of lipoprotein particles provides a compelling attribute that the chemical shifts of lipid molecules transported by these particles are dependent on the particle diameter. This phenomenon arises from the orientational order of the surface lipids and the resulting anisotropy of the magnetic susceptibility, and leads to distinctive particle size-dependent frequency shifts. This facilitates comprehensive lipoprotein analytics that is pertinent to the metabolic constituents of the lipoprotein cascade. Practical applications and statistical considerations have indicated that 14 lipoprotein subclasses and their main lipid constituents can be robustly quantified. <a href="javascript:void(0);" aria-label="reference 3 and 4">(3,4)</a> Multiple commercial methodologies have also been developed. <a href="javascript:void(0);" aria-label="reference 5 to 7">(5−7)</a> Here we applied a platform that has been widely applied in large-scale epidemiology and genetics over the last 15 years with some 500 publications and 2 M samples analyzed, including all the 0.5 M serum samples in the UK Biobank. <a href="javascript:void(0);" aria-label="reference 3, 5 and 8">(3,5,8)</a> This particular platform has also played a key role in yielding open access genetic data, with the most recent genome-wide association study meta-analysis being carried out in 136,000 individuals. <a href="javascript:void(0);" aria-label="reference 9">(9)</a></p><p>Mass spectrometry based lipidomics methodologies have been developed independent of the above and are technologically more challenging than the applications of <sup>1</sup>H NMR spectroscopy. <a href="javascript:void(0);" aria-label="reference 10 to 12">(10−12)</a> Nevertheless, epidemiological applications have become feasible over the recent years and clinical translation has been suggested, for example, with respect to assessing cardiometabolic risk <a href="javascript:void(0);" aria-label="reference 13 and 14">(13,14)</a> and cognitive impairment. <a href="javascript:void(0);" aria-label="reference 15">(15)</a> Initial genetic studies have also been published. <a href="javascript:void(0);" aria-label="reference 16 and 17">(16,17)</a></p><p>The NMR spectroscopy and MS lipidomics approaches to lipid characterization and quantification are fundamentally different (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.analchem.4c03229#fig1" data-tab="pane-pcw-Figures" id="">Figure 1</a>). In NMR the serum sample is directly analyzed with the lipoprotein particles intact; this allows quantification of the comprehensive and specific data on the lipoprotein subclasses and lipids. <a href="javascript:void(0);" aria-label="reference 18">(18)</a> Unlike NMR, LC-MS/MS lipidomics calls for lipid extraction of the serum samples as an integral prerequisite for the analyses. <a href="javascript:void(0);" aria-label="reference 19">(19)</a> The lipidomics sample preparations thus represent pooled mixtures of all the lipid molecules from all the circulating lipoprotein particles. All the information from the specific lipoprotein origin of a certain lipid in the circulation is lost in the extraction phase. However, with LC-MS/MS hundreds of unique lipid species can be analyzed from dozens of different molecular lipid classes. <a href="javascript:void(0);" aria-label="reference 12 and 20">(12,20)</a></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Anal_Chem_2024_96_52_20362_20370_Figure_1_Schematic_illustration_of_the_methodological_differences_and_analytical_characteristics_between_1_H_NMR_and_LC_MSMS_lipidomics_and_their_molecular_views_into_serum_b9907a5e30.jpeg" alt="Anal. Chem. 2024, 96, 52, 20362-20370: Figure 1. Schematic illustration of the methodological differences and analytical characteristics between 1H NMR and LC-MS/MS lipidomics and their molecular views into serum lipids. (A) The lipoprotein analysis with NMR is performed directly from the intact serum sample. (B) For the LC-MS/MS analysis all the lipids need to be extracted to a homogeneous lipid-soluble mixture. This allows LC-MS/MS to reach detailed molecular quantification, however, as a total serum concentration without any information on the originating lipoproteins. (C,D) The NMR analysis gives molecular information on 14 lipoprotein subclasses with the abundant core and surface lipids quantified. The percentages depict the compositional variation of these lipids in different lipoprotein particles." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Anal_Chem_2024_96_52_20362_20370_Figure_1_Schematic_illustration_of_the_methodological_differences_and_analytical_characteristics_between_1_H_NMR_and_LC_MSMS_lipidomics_and_their_molecular_views_into_serum_b9907a5e30.jpeg 192w," sizes="100vw" width="947" height="771"></p><p>Lipoprotein particles are the sole transport vehicles for all lipid molecules in serum, <a href="javascript:void(0);" aria-label="reference 18, 21 and 22">(18,21,22)</a> though albumin contains the bulk of free fatty acids and acylcarnitines, and transports also various lyso-type of lipid molecules. <a href="javascript:void(0);" aria-label="reference 23 and 24">(23,24)</a> The NMR and the LC-MS/MS data on serum essentially represent the same lipids as noted by Ghorasaini et al. <a href="javascript:void(0);" aria-label="reference 25">(25)</a> The NMR provides the size-resolution and metabolic information on lipoprotein particles (209 measures) and the LC-MS/MS lipidomics opens up a prolific and detailed molecular view on all the circulating lipids (809 measures).</p><p>These different methodologies and molecular views to study serum lipids have independently advanced toward large-scale population studies. Here, we integrate these state-of-the-art data─over 1000 quantitative molecular lipid measures per individual─in two large-scale population cohorts of over 7800 participants. These data reveal the fundamental relationships between the lipoprotein subclass cascade and metabolism (NMR) and the plethora of specific molecular information (LC-MS/MS). The molecular and metabolic corollaries are numerous, and we elaborate on some pertinent findings. Among the various analyses we also demonstrate the admirable coherence within the independent experiments and data domains. It is also uncovered─via data-driven, unsupervised neural network analysis─that these molecular lipid measures per se can be utilized for metabolically and clinically meaningful subgrouping of populations. The results illustrate that these combined comprehensive data lead to improved molecular characterization of population-level metabolic health and cardiometabolic risk.</p><h3><strong>Materials and Methods</strong></h3><h5><strong><sup>1</sup>H NMR Spectroscopy</strong></h5><p>We applied an NMR platform that has been widely used in epidemiology and for which the general methodological issues have been published. <a href="javascript:void(0);" aria-label="reference 3, 5, 8, 9 and 18">(3,5,8,9,18)</a> The separation of lipoprotein subclasses by proton NMR spectroscopy is based on particle size, <a href="javascript:void(0);" aria-label="reference 2">(2)</a> the platform resolution being 14 subclasses (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.analchem.4c03229#fig2" data-tab="pane-pcw-Figures" id="">Figure 2</a>). <a href="javascript:void(0);" aria-label="reference 3 and 18">(3,18)</a> Independent verification for the number of subclasses has been published by Mihaleva and co-workers with an in-depth handling of statistical grounds. <a href="javascript:void(0);" aria-label="reference 4">(4)</a> Particle (P), phospholipid (PL), free cholesterol (FC), cholesteryl ester (CE), and triglyceride (TG) concentrations are quantified for all 14 subclasses, also allowing calculation of the relative lipid composition for each lipoprotein subclass. The platform also provides all key clinically used lipid measures (e.g., total TG, cholesterol, and HDL-C) as well as apolipoprotein B (apoB) and A-I (apoA-I) concentrations. In total 209 lipoprotein-related measures were analyzed (98 concentration and 70 compositional measures from 14 lipoprotein subclasses, 19 clinical lipid measures, and 22 measures related to fatty acids, average particle sizes, and apoA-I and apoB).</p><h5><strong>LC-MS/MS Mass Spectrometry</strong></h5><p>Serum lipids were extracted as previously described. <a href="javascript:void(0);" aria-label="reference 19">(19)</a> The LC-MS/MS profiling was performed using the standardized methodology described recently by Huynh et al. <a href="javascript:void(0);" aria-label="reference 12">(12)</a> and updated with a larger set of targets. The mass spectrometric details and parameters are given in the <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.analchem.4c03229/suppl_file/ac4c03229_si_001.pdf">Supporting Information</a>.</p><h3><strong>Conclusions</strong></h3><p>The presented combination of lipoprotein and lipid data from NMR spectroscopy and LC-MS/MS lipidomics led to an unprecedented metabolic and molecular detail with over 1000 measures per person in a population setting of over 7800 individuals. The analyses demonstrated notable coherence between the data from inherently different spectroscopic techniques. The data-driven analyses revealed multiple confirmatory and novel molecular results in relation to systemic lipid metabolism and illustrated the power of all-inclusive lipid data in understanding cardiometabolic population health, related clinical factors, and disease risk. The analyses emphasized the augmented value of interpreting lipidomics data (deep molecular phenotyping) together with lipoprotein data (deep metabolic phenotyping) and association heatmaps between all the lipidomics measures and the key measures characterizing lipoprotein subclass metabolism are provided. These unique motifs are useful as guidelines for the key lipoprotein mediators for various lipidomics associations in biomedical studies when comprehensive lipoprotein profiles are not available.</p>

Personalized Profiling of Lipoprotein and Lipid Metabolism Based on 1018 Measures from Combined Quantitative NMR and LC-MS/MS Platforms

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Since its establishment in 2011, CEITEC has quickly developed into a cutting-edge infrastructure for research which performs highly alongside the best institutes in Europe. Among the main priorities of CEITEC are the promotion of a motivating and dynamic international scientific environment, the provision of state-of-the-art research infrastructure, and the policy of open communication and equal opportunities.

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<p><strong>From Basic to Advanced of Scratch </strong>is a course with three sessions, in which participants will explore strategies for optimizing test parameters, defining critical loads, and utilizing advanced quantitative techniques such as wedge blade testing and coating recovery. This series is designed to enhance your ability to accurately assess and interpret scratch test data, providing insights that are directly applicable to a wide range of material testing scenarios.</p><h3><strong>January 21, 2025:&nbsp;Fundamentals of Scratch&nbsp;</strong></h3><p style="margin:7.5pt 0in .0001pt;">This webinar provides a thorough introduction to the theory and practice of instrumented scratch testing, a critical method for evaluating the mechanical properties of materials under stress. Key topics include the goals of scratch testing, offering insight into why this technique is essential for understanding material behavior. We will explore the fundamental mechanisms that drive scratch testing, review important testing heuristics that guide experimental setups, and discuss strategies for data interpretation to ensure accurate and meaningful results.</p><p style="line-height:normal;">By the end of this webinar, participants will have a solid foundation in scratch testing techniques and their practical applications in material analysis.</p><div><div><blockquote><p><strong>Presenter: </strong>Mark R Haase</p><p>Mark R Haase is an Advanced Application Scientist at Anton Paar, and has been with the company for six years. They work with many material characterization techniques, including scratch, indentation, tribology, particle sizing, gas sorption, atomic force microscopy, and rheology. Mark supports the use of these techniques in research and industry with training and method development. Prior to joining Anton Paar, Mark's studies included nanocarbon materials and green energy systems.</p></blockquote></div></div>

Anton Paar: Beyond the Surface Module 2 - Scratch Series: From Basic to Advanced Scratch

Fundamentals of Scratch

An introduction to the theory of instrumented scratch testing, a critical method for evaluating the mechanical properties of materials under stress.

Scratch Series: Fundamentals of Scratch

<p>Different Cones / Nebulizers / Sample Introduction Systems .. Where and When to Use them</p><blockquote><p><strong>Presenter: </strong>Bert Woods (Application Scientist, Agilent Technologies, Inc.)</p><p><span>Joined the Agilent ICP-MS team in 2004, with previous employment in the semiconductor industry with Dominion Semiconductor (IBM/Toshiba) and Micron. Bert is a 1997 Chemistry graduate of Radford University in Virginia and an avid Washington DC Sports fan.</span></p></blockquote>

Agilent Technologies: Different Cones / Nebulizers / Sample Introduction Systems .. Where and When to Use them

Different Cones / Nebulizers / Sample Introduction Systems .. Where and When to Use them

Different Cones/Nebulizers: When and Where to Use Them

<p><strong>Learn how the Agilent 4300 can deliver an actionable result at site or in production in less than 30 seconds.</strong></p><p>Material testing is critical in all manufacturing and lifecycle processes, as the requirement to do material testing effectively and efficiently in industry becomes even more important.</p><p>During the webinar we will investigate a number of application areas including material degradation, surface cleanliness, material ID and Coating/Adhesive thickness and show effectively how parameters relating to these applications can be measured at site and in production.</p><p><strong>Who should attend:</strong></p><ul><li>Material scientists, coating manufacturers, manufacturers who use coatings within their manufacturing process. Any manufacturing company may be interested in surface contamination.</li></ul><blockquote><p><strong>Presenter: </strong>Donald Inglis (Product Specialist EMEAI for FTIR, Agilent Technologies)</p><p>Donald has worked in analytical instrumentation for over 30 years starting his career as a field service engineer in chromatography and mass spectroscopy before moving into commercial sales. Becoming a product specialist in portable, handheld FTIR and Raman systems over a decade ago at Agilent Technologies.</p></blockquote>

Agilent Technologies: Agilent 4300 Handheld Webinar Series

Sample ID and Material Analysis by Handheld FTIR

Learn how the Agilent 4300 can deliver an actionable result at site or in production in less than 30 seconds.

Agilent 4300 Handheld FTIR - Sample ID and Material Analysis

<p><strong>Balances and scales play a critical role in research and development, quality assurance, and production. Errors in weighing cost time and money, due to rework, waste, and product recalls.</strong></p><p>In order to maintain consistent product quality and comply with standards and regulations, the performance of balances and scales needs to be verified regularly with a calibration. Routine testing of balances or scales in-between these scheduled calibrations helps to maintain accuracy by ensuring early detection of non-conformance with weighing process requirements so that corrective action can be taken in a timely manner.</p><p>This webinar will give you a good understanding of why balance and scale testing is crucial for the accuracy of your weighing results in laboratory and production environments. We explain what your routine testing plan must contain, and, on top of that, we offer an overview of how to perform these routine tests correctly.&nbsp;</p><p><strong>Program</strong></p><ul><li>What routine testing is</li><li>The difference between routine testing, calibration, and adjustment</li><li>The consequences of not testing a balance or scale</li><li>The four pillars of routine testing</li><li>Good Weighing Practice™ (GWP®)</li></ul><blockquote><p><strong>Presenter: </strong>Walter Krebs (Good Weighing Practice™, METTLER TOLEDO)</p></blockquote>

Mettler Toledo: Routine Testing of Balances and Scales 

Routine Testing of Balances and Scales 

Why balance and scale testing is crucial for the accuracy of your weighing results in laboratory and production environments

<p><strong>Canned food is a growing industry around the world. Its sustainable properties and long shelf life offers convenience for busy consumers, strengthening its position as a popular packaging format for both manufacturers and customers. However, as metal cans come in different shapes and sizes, they can present challenges to product inspection technology.</strong></p><p>Whether it's soup, beans, canned vegetables, baby formula, or potato chip tubes, it's important that your canned products reach the end customer free from contaminants and of a high quality; that's where x-ray inspection comes in.</p><p>Join our webinar to discover the wide range of benefits that x-ray inspection offers canned applications - including advanced detection capabilities and integrity and completeness checks. With x-ray inspection technology from METTLER TOLEDO, you can overcome the typical inspection challenges that come with canning applications.</p><p>We don't expect you to just take our word for it - we'll be showcasing our x-ray inspection solutions for canned goods in an exciting and informative live online demonstration. You'll experience how our systems perform in real-time and see for yourself how they can improve your production processes.</p><p><strong>Target audience</strong></p><p>Food Safety Managers, Production or Manufacturing Managers, IT Specialists, Global Food Retailers, Quality Control Specialists, Food Safety Specialists, Production &amp; Packaging, Operation Managers, CEOs, Change Management Agents, Quality Assurance Managers, Quality Assurance Operators.</p><p><strong>Program:</strong></p><ul><li>Learn the different types of canning applications and how x-ray inspection can overcome potential canning inspection challenges</li><li>See how x-ray inspection can improve the quality and integrity of your canned products with capabilities beyond just contamination detection</li><li>Experience a demo of our x-ray inspection system for canned goods and see first-hand how x-ray can benefit your production line</li></ul><p><strong>1/22/2025 9:00, CET</strong><br><strong>1/22/2025 15:00, CET</strong></p><blockquote><p><strong>Presenter: </strong>Adam Green (XR ePlatform Owner &amp; Market Manager)</p><p>Since 2015, Adam has worked in various commercial and technical roles at METTLER TOLEDO. During that time, he facilitated the development of an online demonstration platform to provide technical support to customers due to the global change of working behaviors. He has worked with local markets to help the development of the sales teams that promote X-ray technology and its benefits to customers.</p></blockquote>

Mettler Toledo: Advanced Inspection of Canned Goods with X-ray Inspection

Advanced Inspection of Canned Goods with X-ray Inspection 

Join our webinar to discover the wide range of benefits that x-ray inspection offers canned applications

<p><strong>Nuclear Magnetic Resonance (NMR) technology offers a powerful, versatile solution for food profiling, providing significant return on investment (ROI) through its various applications. This webinar will delve into the basics of NMR, explore specific food profiler solutions, and highlight the versatility of NMR with different upgradation options. Additionally, we will cover statistical analysis using Mestre Software for chemometric analyses of NMR data from various food matrices.</strong></p><div><h3><strong>Key Learning Topics</strong></h3></div><div><div><div><div><div><div><p><strong>Introduction to NMR</strong></p><ul><li>Basics of NMR: Understanding the fundamental principles and applications of Nuclear Magnetic Resonance.</li><li>Avance Chemical Profiling (ACP) for Simple Mixture Analyses: Providing quick and reliable results for straightforward mixture analysis.</li></ul><p><strong>Food Profiler Solutions - Complex Mixture Analysis</strong></p><ul><li>Honey Profiler: Addressing the challenges of honey authenticity control and demonstrating the ROI of using NMR for honey analysis.</li><li>Juice Profiler: Highlighting the benefits of NMR in analyzing juice for purity and composition.</li><li>Wine Profiler: Exploring how NMR can be used to profile wine, ensuring quality control and detecting adulteration.</li><li>Olive Oil Profiler: Emphasizing the advantages of NMR in verifying the authenticity and quality of olive oil.</li></ul><p><strong>NMR as a Versatile Tool</strong></p><ul><li>The BBFO CryoProbe for Routine Work: Enhancing efficiency in routine NMR analyses.</li><li>Solids ,HR-MAS and cryo probes (Liquid Nitrogen and Liquid Helium): Expanding the versatility of NMR to analyze solid, semi-solid and solution samples.<br>&nbsp;</li></ul><p><strong>Statistical Analysis Using Mestre Software</strong></p><ul><li>Presentation from Mestre: Showcasing how the software can be used for chemometric analyses of NMR data from different food matrices. This segment will require approval from the development team to ensure compatibility and effectiveness.</li></ul><div><h3><strong>Who Should Attend</strong></h3></div><div><div><div><div><div><div><p><strong>This webinar is designed for professionals involved in food quality and authenticity, including:</strong></p><ul><li>Food packers, exporters, and importers</li><li>Commercial analytical service providers</li><li>Regulatory or governmental bodies</li><li>Food producer associations</li></ul><p>Join us to gain valuable insights into the applications of NMR technology in food profiling and statistical analysis, and learn how these tools can enhance the authenticity, integrity, and economic viability of various food products.</p><blockquote><p><strong>Presenter: </strong>Ph.D. Pedro Lopes (Field Application Scientist, Bruker BioSpin GmbH, Ettlingen)</p><p>Pedro Lopes holds a doctoral degree in Biophysics with experience in X-Ray Crystallography and High Resolution NMR of Proteins. As a Researcher, he applied High Pressure NMR to Proteins for discovering rare conformational states and new binding sites for interaction with small drugs. He joined Bruker in 2022 where he works as a Field Application Specialist for new solutions in the Applied, Industrial and Clinical Markets</p><p><strong>Presenter: </strong>Uday Ramesh Prabhu (Sales Manager, Biopharma &amp; Applied Division, Bruker India Scientific Pvt.Ltd. Mumbai)</p><p>Uday is currently Sales Manager and Applications Scientist – Cleantech, Industrial and Applied Market (CIAM) division of Bruker Biospin Group. He started his professional career as an Application Scientist with Bruker India Scientific Pvt. Ltd., Mumbai, in 2012. Covering mainly Nuclear Magnetic Resonance (NMR) and Electron Paramagnetic Resonance (EPR/ESR) product portfolio -floor standing and benchtop NMR systems like Minispec and Fourier 80, catering to food and industry markets. Also, in charge of demo lab at Mumbai for benchtop NMR and EPR systems. He obtained his Ph.D. from Indian Institute of Science, Bangalore in 2010, and then pursued post-doc research at the University at Buffalo-SUNY, USA.</p><p><strong>Presenter: </strong>Sandeep Baluni (Strategic Account Director, Mestrelab Research S.L.)</p><p>Mr. Sandeep Baluni holds a Master’s degree in Organic Chemistry and a Postgraduate Certification in AI &amp; ML. He brings over 25 years of diverse experience in business development across prominent organizations, including GSK, Reliance Industries, Elsevier, ACD Labs, and Information Mapping. Currently, working as the Director, Strategic Accounts at Mestrelab Research. Mr. Baluni combines his technical expertise with strategic industry insight to drive innovation and growth in scientific softwaresolutions</p></blockquote></div></div></div></div></div></div></div></div></div></div></div></div>

Bruker: Ensure Food Authenticity & Quality with NMR: Advanced Profiling Solutions

Ensure Food Authenticity & Quality with NMR: Advanced Profiling Solutions

This webinar will delve into the basics of NMR, explore specific food profiler solutions and highlight the versatility of NMR with different upgradation options

Ensure Food Authenticity & Quality with NMR

<div id="zephr-body-wall"><div><p><strong>Determining fats and oils is an important factor in quality control, labeling purposes, product development, and regulatory standard compliance across various industries.</strong></p><p>To date, Soxhlet extraction is widely used in determining the extractable matter on a wide range of sample matrices however, this approach often leads to laboratories encountering significant challenges such as long extraction times and inaccurately determining the composition of fats and oils.</p><p>Join Corey Letizio, national sales manager from VELP Scientifica, as he discusses how you can promptly address your challenges and streamline your extractions to benefit environmental, agricultural, and chemical sectors.</p><p><strong>Key learning objectives:</strong></p><ul><li>Find out how to ensure the accuracy and reproducibility of the extraction process</li><li>Understand the safety measures that need to be in place when working with solvents</li><li>Learn how to optimize extraction conditions while maintaining the reliability of results</li><li>Explore the instruments and accessories needed for an efficient extraction</li><li>Find out how to comply with regulatory standards and guidelines</li></ul><p><strong>Who should attend?</strong></p><ul><li>Professionals working in laboratories of food &amp; feed manufacturers</li><li>Professionals working in contract laboratories in the food &amp; feed, environmental, agricultural, and chemical sectors</li><li>Professionals working in environmental laboratories of wastewater associations and industrial dischargers</li><li>Professionals working in quality control laboratories in pulp and paper, plastics, textile, and oil and gas</li><li>Professionals working in state laboratories, universities, and research entities</li></ul><p><strong>Certificate of attendance</strong></p><p>All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.</p><blockquote><p><strong>Presenter: </strong>Corey Letizio (National sales manager, Velp Scientifica)</p><p>Corey Letizio attended Viterbo University in Wisconsin, USA where he graduated with a marketing degree. Letizio’s growing sales experience over the past seven years has led him into his current role as national sales manager for Velp Scientifica. He has been heavily involved in the analytical instrumentation field, which has provided him with extensive knowledge in the dairy, grain, feed, and general food and agricultural industries.</p><p><strong>Presenter: </strong>Olivia Long (Editorial Team, SelectScience) (moderator)</p></blockquote></div></div>

Select Science: How to successfully face analytical challenges in fats and oils extractions

How to successfully face analytical challenges in fats and oils extractions

Join Corey Letizio - how you can promptly address your challenges and streamline your extractions to benefit environmental, agricultural, and chemical sectors.

Analytical challenges in fats and oils extractions

<p><strong>In this webinar, Bruker nanoscale IR spectroscopy experts show how photothermal AFM-IR can identify the local chemistry of defects. With this detailed knowledge about chemistry, defect origins can be identified and eliminated.</strong></p><p>AFM-IR is a unique, automation-capable technique that reaches beyond the capabilities of bulk spectroscopy or nanoscale elemental analysis methods. It has redefined the boundaries of nanoscale characterization for the semiconductor manufacturing industry.</p><p><strong>Join us for this webinar to learn:</strong></p><ul><li>What AFM-IR is and how it works</li><li>Which parts of the semiconductor manufacturing process could be improved using nanoscale chemical analysis</li><li>What level of automation can be achieved with Bruker’s AFM-IR systems</li></ul><h5>Webinar Abstract</h5><div><p>Semiconductor devices are an essential part of our modern world. Current challenges exist in reducing contamination on wafers and masks, refining existing deposition, etch and growth techniques and improving EUV lithography and photoresist processes. The ability to accurately characterize and measure these materials is critical to improving wafer yields and pushing towards smaller transistors and developing new packaging solutions. Elemental analytical techniques such as EDS/EELS have stepped up to meet the need for higher sensitivity and resolution, but lack chemical specificity in identifying organic materials. AFM-IR is up to the task to identify the origin and narrow down to one of the many processing/inspection steps during which defects may be introduced.</p><p>AFM-IR (atomic force microscopy infrared spectroscopy) combines AFM’s high spatial resolution with IR spectroscopy’s chemical specificity, and has been used by many semiconductor companies to improve product outcomes. Bruker’s Dimension IconIR and Dimension IconIR300 systems work as multifunctional instruments for studying the nanoscale chemistry, along with electrical and mechanical properties of semiconductor devices on wafers up to 300 mm. Automation capabilities and the capability to import coordinates from KLARF allows for considerably higher throughput and the best cost of ownership for nanoscale IR imaging and spectroscopy.</p><p>This webinar highlights AFM-IR's applications in defect identification, process control, and photoresist characterization, and its role in advancing 2D material research for the semiconductor industry. Join us to discover how AFM-IR is redefining the boundaries of nanoscale characterization, and the unique role it can play in semiconductor manufacturing, and how AFM-IR is being used to explore the future of semiconductor devices.</p></div><blockquote><p><strong>Presenter: </strong>Dr. Qichi Hu (Senior Applications Scientist)</p><p>Qichi is currently a Senior Staff Applications Scientist at Bruker Nano. He received a bachelor’s degree from Peking University and Ph.D. from University of British Columbia. He then did postdocs in U.S. university and national labs. Qichi has been working on nanoIR development and applications for over a decade, at Anasys and now at Bruker.</p><p><strong>Presenter:</strong> Chunzeng Li, Ph.D. (Applications Engineer, Bruker)</p><p>Dr. Chunzeng Li is an Applications Engineer with Bruker, Nano Surfaces and Metrology Division, with over 30 years AFM experience. He received his PhD in Physical Chemistry from Xiamen University, China, and is the author of 31 international publications and 2 patents.</p><p><strong>Presenter: </strong>Jin Hee Kim, Ph.D. (Applications Scientist, Bruker)</p><p>Dr. Jinhee Kim is a NanoIR Applications Scientist at Bruker Nano. She received her Ph.D. in materials chemistry from the University of Michigan and completed her postdoctoral appointment at Monash University in Australia. She specialized in nanoIRs since her time in academia and is continuing to apply NanoIR to various fields.</p></blockquote>

Bruker: Nanoscale Chemical Characterization of Semiconductor Materials and Devices using Photothermal AFM-IR

Nanoscale Chemical Characterization of Semiconductor Materials and Devices using Photothermal AFM-IR

In this webinar, Bruker nanoscale IR spectroscopy experts show how photothermal AFM-IR can identify the local chemistry of defects.

Semiconductor Materials and Devices by Photothermal AFM-IR

<p><strong>Join us for an insightful webinar that delves into the innovative capabilities of Laser Direct Infrared (LDIR) Chemical Imaging Spectroscopy. This session will highlight the advanced features of LDIR technology and its critical applications in analyzing microplastics within various matrices. As the environmental impact of microplastics continues to grow, understanding their distribution and composition is essential for effective mitigation strategies.</strong></p><p>We will explore how LDIR enhances our ability to detect and characterize microplastics, providing unparalleled resolution and specificity. Our expert speakers will discuss real-world applications, methodologies, and case studies that demonstrate the effectiveness of LDIR in different contexts, including water, soil, and infant formulas.</p><p><strong>Key Takeaways:</strong></p><ul><li><strong>Understanding LDIR Technology: </strong>Learn about the fundamental principles and features of LDIR Chemical Imaging Spectroscopy.</li><li><strong>Applications in Microplastics Research: </strong>Discover how LDIR can be utilized for accurate detection and analysis of microplastics across various matrices.</li></ul><blockquote><p><strong>Presenter: </strong>Dr. Nopparat Vorapalawut (Spectroscopy Solutions Development Manager, Agilent Technologies)</p><p>Nopparat joined Agilent Technologies in position of Spectroscopy Application Field Service Engineer and is currently Agilent’s Spectroscopy product specialist based in Thailand.</p><p>She graduated Ph.D. in Analytical Chemistry and having previously worked in post-doctoral researcher in France and join Agilent in 2016.</p><p>At Agilent, she is supporting in technical sales and requirement from customers.</p></blockquote>

Agilent Technologies: Using LDIR for Advanced Microplastics Characterization

Using LDIR for Advanced Microplastics Characterization

This session will highlight the advanced features of LDIR technology and its critical applications in analyzing microplastics within various matrices. 

<p><strong>Combustion techniques are revolutionizing food nitrogen/protein analysis with faster workflows, user-friendly operation, and enhanced safety. However, low-level nitrogen samples still present unique challenges due to sample characteristics and method limitations.</strong></p><p>In this approximately 30-minute webinar, Lloyd Allen, Ph.D., LECO's Director of the Technical Services Laboratory, will share practical insights on overcoming these challenges using advanced combustion instruments.</p><p>Discover how to optimize methods for precise, consistent results while leveraging LECO’s innovative solutions to streamline your lab’s workflow and elevate quality control standards.</p><blockquote><p><strong>Presenter: </strong>Lloyd Allen, Ph.D. (LECO's Director of the Technical Services Laboratory)</p></blockquote>

LECO: Protein Done Right with LECO - 1 Method, 1 Calibration, 1 Speed ... Fast 

Optimization of Combustion Methods for Determination of Low-Level Nitrogen-Protein in Food

In this webinar, Lloyd Allen, Ph.D. will share practical insights on overcoming challenges using advanced combustion instruments.