LA-ICPMS for In Situ U–Th Dating of Holocene Stalagmites

Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in week 40, 2024? Check out new documents from the field of spectroscopy, especially ICP/MS techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT ICPMS AND RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">LabRulezGCMS</a> libraries.</blockquote>This week we bring to you applications by Agilent Technologies, Shimadzu, and Metrohm and a poster by Thermo Fisher Scientific!<h4>1. Agilent Technologies: <style type="text/css"></style><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_v_groove_nebulizer_5994_7788en_agilent_4ae77b4b3a.pdf">Reducing Instrument Downtime in Elemental Analysis of Lubricant Oils as per ASTM 5185</a></h4><ul><li>Application</li></ul><h5>Run samples faster and for longer using the V-groove nebulizer</h5>AbstractIn this application note, lubricant oil samples were analyzed using an Agilent 5900 Synchronous Vertical Dual View (SVDV) inductively coupled plasma optical emission spectrometer (ICP-OES) coupled with an Agilent Advanced Valve System 6 (AVS 6) and the Agilent V-groove nebulizer to enable the rapid analysis of over 1,000 samples in 6 hours (more than 160 samples per hour). The V-groove nebulizer provides exceptional performance characteristics, robustness, and durability, even when using troublesome samples. It also provides a reduction in sample loading on the plasma, which reduces carbon formation on the injector of the torch, allowing extended run times, while exceeding the sensitivity requirements required for the ASTM D5185-18 standard method.IntroductionElemental analysis of lubricant and hydraulic oils is essential for predictive and preventive maintenance, as well as trend analysis in many heavy industries. The ASTM D5185‑18 standard method1 is the gold standard in tribology laboratories globally to quantify additive elements, wear metals, and contaminants. This method uses ICP-OES for the rapid elemental determination of 22 elements in both used and unused lubricating and base oils, providing quick screening of used oils for signs of wear.Tribology laboratories typically process hundreds of samples daily; therefore, they are constantly searching for ways to enhance efficiency and improve sample throughput. Instrument downtime caused by blockages in the sample introduction system (SIS) can be a common problem in these high-throughput labs. These blockages are typically caused by suspended particles in the samples blocking the nebulizer, and carbon deposits blocking the injector of the torch. Although various methods exist to remove the blockage from the nebulizer and clean the torch, all require extinguishing the plasma to remove and clean the SIS.The use of a robust nebulizer is a strategy that can enable tribology laboratories to run more samples with reduced blockage. This will improve their workflows and increase sample throughput, reducing both instrument downtime and their running costs. One example of a robust nebulizer that helps to overcome the blockage issues is the inert, high-total-dissolved-solids (high-TDS) Agilent V-groove nebulizer, which is capable of aspirating highly dissolved solids and slurries (up to 30% dissolved solids with a maximum particle size of 350 μm). Its inert construction also ensures that any solvent can be nebulized.In this application note, used diesel engine lubricant oil samples were analyzed using the 5900 SVDV ICP-OES coupled with the AVS 6 and the V-groove nebulizer, following the ASTM D5185-18 standard method.&nbsp;ConclusionThis application note shows the suitability of the Agilent 5900 SVDV ICP-OES used with the Agilent AVS 6 and inert V-groove nebulizer for rapid multi-element analysis of used lubricant oil samples using the ASTM D5185-18 standard method.Excellent long-term stability was demonstrated when more than 1,000 samples were analyzed over a six-hour period (22 to 23 seconds per sample). All measurements of this spiked oil sample were within ± 10% of the expected value, with precision better than 5% RSD in most cases. The spike recovery study showed how the 5900 ICP-OES, used with the inert V-groove nebulizer, can accurately detect low range concentrations of wear metals and high concentrations of the elements from the additive package in a single analysis. The inert V-groove nebulizer also enabled the samples to be run faster, with excellent accuracy.Despite no oxygen injection being used, there were no signs of blockage of the injector of the torch, or carbon deposition after the test. The V-groove nebulizer design reduces sample loading on the plasma, minimizing carbon buildup while maintaining the sensitivity required for the ASTM D5185 standard method. No nebulizer blockage was experienced while collecting the data for this study. The inert V-groove nebulizer allows extended run times by reducing the frequency of torch and nebulizer maintenance. This demonstrates the stability of the 5900 ICP-OES and the suitability of the inert V-groove nebulizer for high-throughput tribology laboratories, by reducing instrument maintenance downtime and improving sample throughput.<h4>2. Thermo Fisher Scientific: <style type="text/css"></style><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/pn_002807_tea_icp_ms_halogens_wpc_2024_pn002807_en_b235f7ba82.pdf">WPC: Sensitive and interference free analysis of halogens using triple quadrupole ICP-MS</a></h4><ul><li>Poster / WPC</li></ul>ABSTRACTThe analysis of halogens is important in many different industries, such as environmental monitoring, pharmaceutical, oil and gas, but also Li-ion battery and renewable fuels. Halogen analysis is commonly carried out using ion chromatography (IC), whereas argon plasma-based techniques like ICP-MS are less common, due to poor sensitivitiy, and potential spectral interferences. This study describes a complete analytical workflow using the Thermo Scientific™ iCAP™ TQe ICP-MS for the accurate and precise quantification of challenging halogen analytes like fluorine, chlorine, and bromine.CONCLUSIONSThis work highlights how triple quadrupole ICP-MS systems, such as the iCAP TQe ICP-MS, operated in TQ-O 2 mode can be used for accurate and precise quantification of challenging analytes such as halogens.<ul><li>It could be shown that chlorine and bromine can be analyzed directly using optimized instrument conditions.</li><li>It further highlights the feasibility of iCAP TQe ICP-MS for indirect but accurate and precise determination of fluorine by following approach of complex formation with barium under optimized and controlled conditions</li><li>The analytical data and observations made during this study strongly suggest that iCAP TQe ICP-MS equipped with dedicated mass flow controllers (MFCs) for introduction of pure oxygen and pure helium as cell gases is a powerful tool to accomplish the otherwise challenging analysis of halogens.</li><li>Upcoming studies will focus on the application of the fluorine measurements in hyphenated techniques, such as liquid chromatography hyphenated to ICP-MS to assess the potential for emerging contaminant screening, i.e. of PFAS</li></ul><h4>3. Shimadzu: <style type="text/css"></style><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_00772_en_4935e06938.pdf">Analysis of Elemental Impurities in Anode Materials for Lithium-Ion Secondary Batteries Using the ICPE- 9820</a></h4><ul><li>Application</li></ul>User Benefits<ul><li>Elemental impurities in the anode materials of lithium-ion secondary batteries can be measured.</li><li>Even after measurement, elements and wavelengths can be added to check for unexpected elemental impurities in the anode materials.</li><li>The system uses a mini torch that consumes less argon gas, thus reducing running costs.</li></ul>IntroductionLithium-ion secondary batteries (LIBs) are widely used in mobile devices, electric vehicles, hybrid cars, and more. One of the components of LIBs, the anode, accumulates and releases Li ions during charging and discharging. Graphite-based materials are mainly used as the anode material in LIBs. In China, one of the major producers, the analysis of elemental impurities in graphite, which is used as LIB anode material, is required by GB/T 24533-20191) using inductively coupled plasma atomic emission spectroscopy (ICP-AES).In this Application News, elemental impurities in LIB anode materials were analyzed using the ICPE-9820. Spike recovery tests were performed to confirm the validity of the analytical values. Additionally, the “Acquisition for All Wavelength” feature allows for checking the presence of elemental impurities that were not subjected to quantitative analysis.ConclusionIn this Application News, an analysis of elemental impurities in LIB anode materials was performed using the ICPE-9820. Good spike recoveries were obtained, confirming the accuracy of the analysis. Additionally, elements and wavelengths were added after the measurement to identify elemental impurities other than the analyzed elements present in the anode materials.<h4>4. Metrohm: <style type="text/css"></style><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_pan_1064_download_39b556efd8.pdf">Monitoring complexing agents in galvanic baths inline with Raman spectroscopy</a></h4><ul><li>Application</li></ul>The main purposes of galvanic process baths include the surface refinement of workpieces and the setting of physical properties. To this end, bath additives (e.g., organic compounds or complexing agents) are regularly added in different amounts, depending on the processing load. Since the bath composition changes continuously due to the introduction of the workpieces, close monitoring of the concentration of the bath additives is necessary to ensure that the end product quality is at the highest level.This Process Application Note presents a method to accurately analyze complexing agents inline in galvanic baths with a 2060 Raman Analyzer from Metrohm Process Analytics. This enables real-time bath control and thus an increase in production efficiency and product quality.CONCLUSIONRaman spectroscopy is an easy-to-use analytical technique that identifies liquids and solids within seconds. The 2060 Raman Analyzer from Metrohm Process Analytics is a high-performance Raman system designed for monitoring different processes like electroplating.Together with Metrohm’s Vision and IMPACT software, the 2060 Raman Analyzer can be used to acquire real-time results, increase roductivity, and lower production costs.

News from LabRulezICPMS Library - Week 40, 2024

In the week from October 7, the following webinars await you in the field of atomic and molecular spectroscopy and spectrometry<blockquote><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinars">👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</a>👉 Search and filter in the largest global database with over 3 500 GC, LC, MS and spectroscopy webinars.</blockquote><h5>1. Bruker: Fast and efficient authenticity screening of fruit and vegetable juices – insight into the work of SGF International</h5><ul><li>We, 9.10.2024 14:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/4237">Registration</a></li></ul><div>How NMR Juice-Profiling is used on a daily basis by SGF International e.V. for industrial self-control of fruit and vegetable juices.<div>2.&nbsp;Anton Paar: Solid Density in the Additive Manufacturing Industry</div><ul><li><div>We, 9.10.2024 20:00 CEST</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/4340">Registration</a></div></li></ul><div>In this webinar, we will show how these properties can be measured with high accuracy and repeatability for powders through extrusions.</div></div>

Webinars LabRulezICPMS Week 41/2024

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Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

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Anton Paar

Agilent Technologies

Bruker

Quantum Analytics

This online seminar will show how NMR Juice-Profiling is used on a daily basis by SGF International e.V. for industrial self-control of fruit and vegetable juices.
Questions regarding the authenticity assessment of fruit and vegetable juices, to which NMR Juice-Profiling can provide initial answers, will be explained.
The online seminar will also provide a brief introduction to how the results of NMR Juice-Profiling in combination with other analytical methods allow for a comprehensive professional evaluation.
Key Learning Topics
<ul>
<li>Usage of NMR Juice-Profiling in daily routine analyses of fruit and vegetable juices.
</li>
<li>Interpretation of the analysis results – which conventional analysis complements NMR Juice-Profiling?
</li>
</ul>
What To Expect
<ul>
<li>This online seminar is aimed at those responsible for quality management and control in fruit and vegetable processing and bottling companies, decision-makers in commercial laboratories and regulatory or governmental bodies.</li>
</ul>
<blockquote>
Presenter: Markus Jungen (Technical Manager, SGF International e.V.)
</blockquote>
<blockquote>
The Juice-Profiling methodology, a robust tool, not only expedites the evaluation of authenticity in fruit juices but also extends its reach to encompass vegetable juices. By harmonizing quantitative scrutiny of constituent elements and intricate statistical analyses of profiles, including provenance, this method offers a comprehensive and efficient means of discerning the authenticity of both fruit and vegetable juices.
</blockquote>
<blockquote>
Presenter: Léa Heintz (Product Manager, Biopharma &amp; Applied Division, Bruker BioSpin GmbH &amp; Co. KG)
</blockquote>
<blockquote>
Léa Heintz is in charge of the Functional Food &amp; Nutrition product portfolio. Holding a Master of Science’s degree in Analytical Chemistry, she works in close collaboration with the development, sales and marketing teams. Her main focus is to translate the customer needs into innovative solutions.
</blockquote>

Bruker: Fast and efficient authenticity screening of fruit and vegetable juices – insight into the work of SGF International

Fast and efficient authenticity screening of fruit and vegetable juices – insight into the work of SGF International

How NMR Juice-Profiling is used on a daily basis by SGF International e.V. for industrial self-control of fruit and vegetable juices.

Fast and efficient authenticity screening of fruit and veget

Join us for an exclusive one-day hybrid event, here we&#39;ll explore the latest trends and innovations in microplastics analysis. The morning session will be live-streamed and recorded, allowing virtual articipation for those unable to attend in person.
We are excited to invite you to a special hybrid event in partnership with i3 Membrane, where we will delve into the latest trends and innovations in microplastics analysis. Whether you join us in person or virtually, you’ll gain invaluable insights and hands-on experience.
Event also available in live stream
<h3>Agenda:</h3>
<ul>
<li>Morning session: Gain key insights into <a href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=microplastics+analysis">microplastics analysis</a>, as well as <a href="https://lcms.labrulez.com/library?mainauthorItems=10&amp;search=PFAS">PFAS</a> and other environmental contaminants, through engaging presentations by top researchers and industry experts.
</li>
<li>Afternoon session: Participate in interactive workshops designed to enhance your practical skills in sample preparation. This provides a unique opportunity to master advanced techniques and methodologies under the guidance of professionals. Attend a live demo on the IR QCL-based <a href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=8700+LDIR">8700 LDIR</a>. Additionally, enjoy a guided laboratory tour offering an exclusive glimpse into the state-of-the-art facilities at the HEREON campus.
</li>
</ul>
<h5>9:15 a.m. - Welcome</h5>
<h5>9:20 a.m. - From Macroplastics to Mesoplastics: Challenges and Solutions</h5>
<ul>
<li>Dr. Marion Börger, Agilent Technologies,</li>
<li>Dr. Andreas Kerstan, Agilent Technologies</li>
</ul>
<h5>9:40 a.m. - i3 Membrane Session: Filter Membranes/Packaging - Jacobs</h5>
<ul>
<li>Kathrin Hahn, i3 Membrane</li>
</ul>
<h5>10:00 a.m. - Exploring Microplastic Sources and Distribution in Australian Soils</h5>
<ul>
<li>Subharthe Samandra, University of Melbourne</li>
</ul>
<h5>10:20 a.m. - Advancing Analysis: Eurofins&#39; Path to ISO 17025 Accreditation for Microplastics Testing</h5>
<ul>
<li>Julia Jäger, Eurofins</li>
</ul>
<h5>10:40 a.m. - Coffee Break</h5>
<h5>11:00 a.m. - Validation and Application of LDIR Imaging to Analyze Microplastics in Marine Samples</h5>
<ul>
<li>Lars Hildebrandt, Hereon</li>
</ul>
<h5>11:20 a.m. - Applying Multiple Analytical Techniques to Answer Open Questions About Offshore Wind</h5>
<ul>
<li>Alexa Zonderman, Hereon</li>
</ul>
<h5>11:40 a.m. - Sample-Based Subsampling Strategies to Analyze Large Quantities of Particles in LDIR</h5>
<ul>
<li>Manuel Andrade, University La Coruna</li>
</ul>
<h5>12:00 p.m. - Beyond the Surface: Spotlight on Plastic [Metal(loid)] Additive Leaching and Unseen Contaminants</h5>
<ul>
<li>Ole Klein, Hereon</li>
</ul>
<h5>12:20 p.m. - Microplastics back in food- Advantages of Thermal Desorption for a wide range of Samples</h5>
<h5>12:40 p.m. - Struggling with Solvent Effects During the Analysis of PFAS</h5>
<ul>
<li>Dr. Axel Ritter, Agilent Technologies</li>
</ul>
<h5>1:00 p.m. - Lunch Break</h5>
<h5>2:00 p.m. - An Analytical Toolbox to Unravel PFAS Source Fingerprints</h5>
<ul>
<li>Frank Menger, Hereon</li>
</ul>
<h5>2:20 p.m. - LDIR for Assessment of Microplastics in the VAMAS Ring Trial and Tissue in a Murine Infection Model</h5>
<ul>
<li>Christoph Krafft, IPHT</li>
</ul>
<h5>2:40 p.m. - Label-Free Infrared Spectroscopic Micro- and Nanoplastics Detection in Complex Matrices</h5>
<ul>
<li>Markus Brandstetter, Recendt</li>
</ul>
<h5>3:00 p.m. - Break in Dividing the Guests into Subgroups</h5>
<h5>3:10 p.m. - Lab Visits: Organic Lab, Microplastics Lab, Sample Prep, LDIR, and Other Techniques</h5>
<h5>4:50 p.m. - Wrap up</h5>
<h3>Meeting Information</h3>
<ul>
<li>Date: 29 October 2024
</li>
<li>Time: 9:00 a.m. to 4:50 p.m. CEST
</li>
<li>Location: GITZ GmbH, Max-Planck-Straße 2, 21502 Geesthacht, Germany 
</li>
<li>Meals included: Enjoy complimentary lunch and snacks during the event.
</li>
</ul>
Limited spots available! Hurry, to secure yours today.
<blockquote>
<a href="https://explore.agilent.com/microplameeting24#form">Secure your spot</a>
</blockquote>

Agilent Microplastics Meeting 2024

We'll explore the latest trends and innovations in microplastics analysis.

NMR is a very versatile tool in structural biology, offering new capabilities in protein structure resolution. With (ultra)-high field instruments and AI-based software solutions, it's now more applicable and efficient, enabling precise identification of binding molecules and interaction characterization, thus revitalizing its importance in early drug discovery programs, amongst other applications.As part of a fragment-based drug discovery program, we demonstrate how we solved a 20-kDa cancer related protein structure in a timeframe competitive with X-ray crystallography or cryo-EM. The atomic resolution structure obtained together with 15N-1H-HSQC CSP reveals very clear to derive binding poses of millimolar affinity fragment identified during LO-NMR screening campaigns. A complex protein/ligand structure from the NovAFraG library is exemplified. The minimal NMR dataset necessary to get assignments and calculate structures is deeply investigated throughout this real-case study, in a constant search for optimized workflows. We are also going to give an outlook of other applications enabled by easy access to protein assignments.At the end of the seminar, you will have an understanding of what you can get from the AI-based NMRtist platform and an optimized NMR data acquisition scheme. You will also get a detailed view on how the results obtained can be used for further analysis such as ligand interactions studies.<h4>Key Learning Topics</h4><ul><li>Rapid automated NMR protein structure determination &nbsp;</li><li>(Ultra)-High field NMR &nbsp;</li><li>NMR for low affinity fragment binding poses</li></ul><blockquote>Presenter: Dr. Marc Vitorino (Head of NMR, NovAliX, Strasbourg, France)I am a structural biologist by training who chose early in his career to join the industry and the field of early drug discovery.After completing my Ph.D. in France, I moved to Cambridge as a research associate in the biophysics group of Dr. Glyn Williams at Astex Therapeutics, where I specialized in applying the technique of liquid-state NMR spectroscopy to identify new fragments, that could potentially lead to new approved drugs on the market. &nbsp;At NovAliX, as head of the NMR platform within the biophysics group of Dr. Renaud Morales, I am mainly interested in applying the technique of liquid-state NMR spectroscopy with fragment libraries to study different therapeutical target proteins, identify new binding molecules and characterise the interaction between the fragment and the protein of interest. To help our customers initiate their early drug discovery programs, I work on developing methods to make the liquid-state NMR technique more applicable.Presenter:&nbsp;Dr. Daniel Mathieu (Application Scientist, Bruker BioSpin)Daniel started studying Chemistry at the Goethe University in Frankfurt in 2001.In 2007 he got his diploma in Chemistry. He then joined the group of Professor Harald Schwalbe at the University of Frankfurt for his PhD thesis developing NMR methodology for RNA and peptides, which he finished in 2011.Since 2011 he’s an application scientist at Bruker BioSpin in Germany, focusing on Biomolecular NMR.</blockquote>

Bruker: Automated NMR for Protein Assignment and Structure Determination in a Timely and Affordable Way

Automated NMR for Protein Assignment and Structure Determination in a Timely and Affordable Way

What can you get from the AI-based NMRtist platform and an optimized NMR data acquisition scheme.

Automated NMR for Protein Assignment and Structure

Solid density, both tapped and skeletal, is an important property used to characterize metal powders and other materials used in the additive manufacturing industry. These properties are important in evaluation of both raw materials and final products. The purity and porosity of both powders and solids/extrusions can be readily determined using skeletal density measurements. And the tapped density can be correlated to bulk volume, particle morphology, and powder flow information.In this webinar, we will show how these properties can be measured with high accuracy and repeatability for powders through extrusions.<blockquote>Presenter: Alyssa Henderson, Ph.D.&nbsp;Dr. Henderson, a Product Manager specializing in semi-solid and solid density meters/porometers and porosimeters at Anton Paar QuantaTec, brings eight years of experience in materials characterization to the role. With three years of focused experience in porous materials, she possesses a deep understanding of the field. Dr. Henderson earned her Ph.D. in materials physics from Florida State University. She has conducted extensive training for over 200 associates and customers globally, covering gas adsorption, solid density, and related theories, techniques, applications, and instruments. Her expertise is recognized through presentations at major conferences, and she provides daily guidance to researchers on experimental design and data interpretation.</blockquote>

Anton Paar: Solid Density in the Additive Manufacturing Industry

Solid Density in the Additive Manufacturing Industry

We will show how these properties can be measured with high accuracy and repeatability for powders through extrusions.

What to expect?Micro-XRF as an analytical technique has a wide range of possible applications, but it is often considered to be most suitable for research labs and academic environments. This sentiment is needlessly restrictive - micro-XRF can be applied just as well across multiple stages of industrial processes.For the materials testing of incoming goods - a task where bulk XRF is well-established - micro-XRF can go one step beyond precise quantitative analysis by also revealing component level alterations, be they accidental or intentional.While true in-line analysis of products remains a very challenging task, investigating individual conspicuous components is another area of application. The origin of changed material properties like colour, wear or corrosion resistance may, for example, be traced back to the inclusion of foreign bodies that hint at wear of machinery in the production process.For quality control, micro-XRF can assist by providing measures of layer thickness, composition, and the homogeneity of crystal structure orientation.This webinar highlights how micro-XRF is a versatile and powerful technique suitable for use in various industrial processes, not just academic research. Examples that will be presented include the quality control of thin layer samples and foreign body identification in the manufacturing process of battery electrodes.Who should attend?<ul><li>Micro-XRF users in industry</li><li>Quality control specialists assuring composition of metal or glass samples as well as failure analysis specialists in industry and material research laboratories</li><li>Researchers who work in R&amp;D</li></ul>Live Session 1* October 15th<ul><li>10 am CEST / Berlin</li><li>4 pm SGT / Singapore</li><li>5 pm JST / Tokyo</li></ul>Live Session 2* October 15th<ul><li>5 pm CEST / Berlin</li><li>8 am PDT / Los Angeles</li><li>11 am EDT / New York</li></ul>* the content of both sessions is identicalPresenter: Falk Reinhardt (Senior Application Scientist micro-XRF, Bruker Nano Analytics)Presenter: Dr. Christian Hirschle (Application Scientist micro-XRF, Bruker Nano Analytics)

Bruker: Industrial applications of micro-XRF – Quality control at different stage

Industrial applications of micro-XRF – Quality control at different stages

Micro-XRF is a versatile and powerful technique suitable for use in various industrial processes, not just academic research.

Industrial applications of micro-XRF

Elemental impurities pose risks to pharmaceutical quality and efficacy, necessitating accurate and precise analysis within drug development and control. Since 2018, ICH Q3D guideline and USP &lt;232&gt; have imposed stringent limits for toxic elements like Cd, Pb, As, and Hg. USP &lt;233&gt; also requires robust sample preparation prior to ICP-OES or ICP-MS analysis. This webinar will discuss microwave-assisted closed vessel digestion as the ideal sample preparation method for compliant elemental analysis.This webinar focuses on sample preparation for elemental impurity analysis in pharmaceuticals, including a survey of the regulatory background of ICH Q3D and USP &lt;232&gt;/&lt;233&gt;. It will provide an overview of sample preparation basics, with a particular emphasis on microwave-assisted acid digestion techniques.Additionally, the session will discuss application examples covering a range of samples, from simpler to more complex substances such as tricyclic and tetracyclic compounds.Essential topics in relation to sample preparation of pharmaceutical products and raw materials for elemental impurity analysis:<ul><li>Regulatory framework overview, with a focus on ICH Q3D and USP &lt;232&gt;/&lt;233&gt; guidelines.</li><li>Fundamentals of sample preparation, emphasizing microwave-assisted acid digestion techniques.</li><li>Practical application examples ranging from simpler samples to highly challenging substances such as tricyclic and tetracyclic APIs.</li><li>Analysis of elements including the "big four" (Hg, As, Cd, Pb) and how to achieve acceptable recovery rates, even for Os.</li></ul>Who should attend?<ul><li>Lab chemists doing trace metal analysis of pharmaceuticals (raw materials and finished products) in R&amp;D, QC or analytical contract labs</li><li>Analytical chemists in state or municipal laboratories</li><li>Laboratory managers of ICP and trace metal labs</li><li>Academic chemists</li></ul><blockquote>Presenter: Klaus Pichler-Jöbstl&nbsp;Klaus Pichler-Jöbstl holds a degree in Technical Chemistry and Environmental Technology. He started his career in 1996 at Fresenius-Kabi, a global pharmaceutical company. Initially, he led the chromatography department in quality control and subsequently established and managed the method transfer and validation department for all analytical methods, including wet chemistry, physical measurement methods, chromatography, and spectroscopy.Since 2014, Klaus has been at Anton Paar GmbH in Graz, where he leads a team of chemists overseeing all application-related topics from product development to after-sales support for microwave-assisted acid digestion and synthesis instruments.</blockquote>

Anton Paar: USP-Compliant Sample Preparation: Best Microwave Digestion Practices to Prepare Samples for ICP Analysis

USP-Compliant Sample Preparation: Best Microwave Digestion Practices to Prepare Samples for ICP Analysis

This webinar will discuss microwave-assisted closed vessel digestion as the ideal sample preparation method for compliant elemental analysis.

Best MW Digestion to Prepare Samples for ICP Analysis

Solid form analysis is a critical step in drug development and quality control processes that helps to ensure final drug products meet all necessary performance and safety criteria. This is especially important for small molecule active pharmaceutical ingredients (APIs) which can arrange in different crystal structures (polymorphs) that may vary significantly in terms of their physicochemical properties. Selection of the correct polymorph is therefore vital and requires a deep understanding of the different possible structures and their stability over time or under various storage conditions during the development process.Powder X-ray diffraction (XRD) is an ideal tool for solid form analysis, as different polymorphs can be easily identified due to changes in the diffraction pattern. It can therefore be used during development and in QC batch release testing to ensure the correct polymorph of a sample is present. Anton Paar’s XRD solutions offer 21 CFR Part 11 and GxP-compliant measurements with the highest sensitivity to even the smallest impurity phases.In this webinar, you will get an overview of XRD for solid form analysis and how the method can be applied in regulated environments like the pharmaceutical industry. You will get insights into:<ul><li>How XRD can be applied to pharmaceutical materials</li><li>New opportunities in solid form analysis made possible by next-gen XRD instrumentation</li><li>How XRDynamic 500 supports the requirements of 21 CFR Part 11</li><li>Application examples</li></ul>Target group:<ul><li>Anyone interested in solid form analysis of pharmaceuticals via XRD</li><li>Researchers who want to extend their polymorph screening capabilities with the latest instrumentation</li><li>Lab managers looking to perform XRD measurements in a regulated environment</li></ul>Oct 16, 2024, 08:00 - 09:00 (CEST UTC+02:00)<ul><li>Dr. Linda Kuenstl (English)</li></ul>Oct 16, 2024, 18:00 - 19:00 (CEST UTC+02:00)<ul><li>Dr. Linda Kuenstl (English) &nbsp;</li></ul>Presenter: Dr. Linda Kuenstl

Anton Paar: Driving XRD in regulated environments: Solid form analysis with XRDynamic 500

Driving XRD in regulated environments: Solid form analysis with XRDynamic 500

Get an overview of XRD for solid form analysis and how the method can be applied in the pharmaceutical industry.

Solid form analysis with XRDynamic 500

We kindly invite you to join us for this live webinar: An Introduction to Nanoscale Infrared Spectroscopy and Imaging with Photothermal AFM-IR. Infrared (IR) spectroscopy is a commonly used characterization technique for organic materials and many inorganic compounds and crystals. While powerful, it is limited by the diffraction limit to resolution on the order of several microns, and the lateral resolution is strongly dependent on the wavelength. Photothermal AFM-IR&nbsp;is a novel technique which offers IR spectroscopy and imaging on materials with a lateral resolution 1000x better than traditional FTIR and &lt;1 nm detection sensitivity with model-free interpretation. AFM-IR achieves this by using an AFM probe as the detector of photothermal expansion. This opens a variety of applications on both organic and inorganic materials where nanometer sensitivity and resolution are key.<div> In this webinar we will:</div><ul><li>Introduce the photothermal AFM-IR technique</li><li>Explore the surprisingly simple mechanism underlying the technique</li><li>Highlight a few of its many broad applications</li><li>Offer a demonstration of photothermal AFM-IR on the Dimension IconIR system</li></ul><blockquote>Presenter: Peter De Wolf, Ph.D., (Director of Technology &amp; Application Development)Peter De Wolf is director for AFM technology &amp; application development at Bruker Nano Surfaces, covering all applications related to Scanning Probe Microscopy (SPM). He obtained his PhD from IMEC, Belgium on the development of new SPM methods for 2D carrier profiling in semiconductors and has more than 25 years of experience on SPM. He is the author and co-author of over 30 publications related to electrical characterization using SPM. He also owns several SPM patents, and developed several new SPM modes for electrical characterization.Presenter: Cassandra Phillips, Ph.D. (Application Scientist, Bruker)Cassandra did her Ph.D. at the University of Toronto exploring the photophysics of boron nitride nanotubes using scattering scanning nearfield optical microscopy (s-SNOM) and computational models. She has been working at Bruker Nano Surfaces and Metrology since September 2019 as an Applications Scientist focusing on nanoscale IR spectro-microscopy and other correlated imaging techniques realized with atomic force microscopy.Presenter: Dr. Qichi Hu, (Senior Applications Scientist )Qichi is currently a Senior Staff Applications Scientist at Bruker Nano. He received a bachelor’s degree from Peking University and Ph.D. from University of British Columbia. He then did postdocs in U.S. university and national labs. Qichi has been working on nanoIR development and applications for over a decade, at Anasys and now at Bruker.</blockquote>

Bruker: Introduction to Nanoscale Infrared Spectroscopy and Imaging with Photothermal AFM-IR

Introduction to Nanoscale Infrared Spectroscopy and Imaging with Photothermal AFM-IR

An Introduction to Nanoscale Infrared Spectroscopy and Imaging with Photothermal AFM-IR.

Nanoscale IR Spectroscopy / Imaging with Photothermal AFM-IR

Unlock a new level of precision and ease in your industrial operations with our upcoming webinar on FTIR gas analysis. Traditionally, gas analyzers demanded extensive expertise and complex setups, but Bruker has revolutionized this with cutting-edge technology that simplifies and accelerates the process of analyzing gaseous mixtures.Discover how innovative FTIR-based gas analysis systems, the Bruker MATRIX II-MG Series and the OMEGA 5 Gas Analysis System offer unparalleled dynamic range and effortless integration into any industrial setting. User-friendly interface and intuitive software make around-the-clock monitoring a breeze, providing real-time alerts when critical thresholds are missed. From power plants to production facilities, Bruker’s FTIR-based gas analyzers fit seamlessly into your existing workflows with remote control capabilities designed to enhance your operational efficiency.Join us to explore how state-of-the-art FTIR technology can transform your approach to gas analysis, making it simpler, more accurate, and adaptable to even the harshest industrial environments.Key takeaways will include:<ul><li>Modern FTIR gas analysis methods can dramatically simplify your operations.</li><li>Advanced analyzers that can easily integrate into your existing infrastructure.</li><li>Robust equipment designed to withstand challenging industrial conditions.</li><li>Elevate your gas analysis game and drive unparalleled efficiency in your production processes. Don’t miss out—click here to register today!</li></ul>

Quantum Analytics: Unleashing the Power of FTIR-Based Gas Analysis

Unleashing the Power of FTIR-Based Gas Analysis

State-of-the-art FTIR-based gas analysis technology can transform your approach to gas analysis

Dear Customer,Don’t miss this opportunity to learn how battery material characterization techniques can help you manufacture high-quality top-performing batteries! Battery safety, performance and lifetime are only as good as the materials that go into making the batteries. At our not-to-be-missed Anton Paar Battery Days Webinar, you will learn how to characterize material properties and apply the results to optimize your manufacturing process.Webinar highlights:<ul><li>How to characterize solid electrode materials to increase the battery performance and lifecycle</li><li>How to attain desired structural properties of slurries so they retain their homogeneity</li><li>How to guarantee the quality of the battery electrolyte</li><li>How to apply X-ray diffraction analysis techniques for battery powder analysis and battery cell characterization</li></ul>Talk with the experts:<ul><li>After the Battery Days Webinar you and your company will also have a possibility to book a private meeting with one (or several) of our experts to talk about your applications and needs in more detailed.</li><li>These private meetings will be held on Wednesday morning the 23rd of October 2024.</li><li>Each meeting can be customized based on your needs and interests.</li><li>If the meeting sounds interesting for you and your company please register fast since there are only limited timeslots available!</li></ul>If you like to book you talk with expert please write in the box for message and our local sales representatives will contact you for more detailed planning.Last day for registration is October 15, 2024.

Anton Paar: Anton Paar Battery Days Webinar

Anton Paar Battery Days Webinar

Learn how to characterize material properties and apply the results to optimize your manufacturing process.