The international standard ISO/IEC 17025 [1] clause 7.7.2 with regards to ensuring the validity of results, requires a laboratory to participate in proficiency testing (PT) and/or to participate in interlaboratory comparisons (ILCs) other than PT. However, no guidance as to what these other ILCs might be, or indeed how they might compare in relation to PT, is provided. This leaflet aims to outline other ILCs available, pointing out some of the limitations as compared to PT.&nbsp;There are three major types of ILCs in which a group of laboratories analyses identical portions from a homogeneous, stable test sample, with each type being characterized by its intended purpose [2,3]:<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Interlaboratory_comparisons_other_than_proficiency_testing_2_d9263807fb.jpg" alt="Eurachem: Interlaboratory comparisons other than proficiency testing" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Interlaboratory_comparisons_other_than_proficiency_testing_2_d9263807fb.jpg 245w," sizes="100vw" width="1507" height="607">A key point is that PT is an ILC that is designed to specifically evaluate the performance of participants, providing them with an infrastructure to monitor and assess the validity of their results. This is not the key purpose of the two other ILCs, and thus depending on their intended purpose they have a number of limitations that laboratories need to be aware of when using them rather than PT. Only proficiency testing should have been conducted in full compliance to the competency standard ISO/IEC 17043 [4].&nbsp;<h4>Evaluation of measurement procedure performance&nbsp;</h4>These ILCs, are designed to assess how a particular measurement procedure performs and whether it is fit for its intended purpose. These ILCs are often referred to as a ‘method performance study’ or a ‘collaborative study’ [2]. Some limitations of using such ILCs for monitoring laboratory performance as an alternative to PT are:&nbsp;<ul><li>All participants use the same measurement procedure i.e. the measurement procedure that is being validated. Unless the measurement procedure is being routinely used by the participating laboratory such an ILC will not assess the routine performance of the laboratory using their own routine measurement procedure. Nor does it enable them to compare their performance with other laboratories using alternative measurement procedures.&nbsp;</li><li>The measurement procedure is likely to be new, so participants may not have established stable procedures and quality control, so performance may not reflect routine use.&nbsp;</li><li>The report from such an ILC would not provide information on the performance of the participant, if the statistical model used makes the assumption that all laboratories perform with equal variability.</li><li>The design of the study may require the participants to assess multiple samples and/or to undertake multiple replicate analysis on the test materials. This may not be representative of the routine measurements or tests undertaken by the laboratory.&nbsp;</li><li>The conclusion of the ILC might be that the measurement procedure being assessed is not valid.&nbsp;</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Interlaboratory_comparisons_other_than_proficiency_testing_3_a53ecd2f5d.jpg" alt="Eurachem: Interlaboratory comparisons other than proficiency testing" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Interlaboratory_comparisons_other_than_proficiency_testing_3_a53ecd2f5d.jpg 157w," sizes="100vw" width="570" height="566"><h4>Characterisation of candidate reference materials&nbsp;</h4>These are ILCs that assign a property value to a candidate reference material, usually with a stated measurement uncertainty. These are often referred to as a ‘material certification study’ [2]. Limitations of using such ILCs as an alternative to PT are:&nbsp;<ul><li>The analysis of the candidate reference material is likely to require additional care in exercising the routine measurement procedure, such as substantially more replication, and/or may require quite different reporting formats (e.g. all valid replicates instead of a mean result). Thus, such an ILC will not necessarily provide an evaluation of the performance of the laboratory based on the routine use of their measurement procedures.&nbsp;</li><li>The report from such an ILC may include the results from the participating laboratories but would not provide information on the performance of each laboratory.&nbsp;</li><li>Participating laboratories may be required to assess multiple samples and/or to undertake multiple replicate analysis on the candidate reference materials. Thus this may not be representative of the routine measurements or tests undertaken by the laboratory.&nbsp;</li></ul><h4>Other ILCs&nbsp;</h4>Some other ILCs, whilst not being conducted in full compliance of the requirements of ISO/IEC 17043, may be designed to evaluate participant performance. These would include small ILCs as defined by EA‑2/21 [5] or split sample ILCs i.e. where a portion of a single sample is sent to two or three laboratories. Whilst these ILCs are specifically designed to evaluate participant performance, they may not provide a comprehensive comparison that a PT might provide. In such cases the laboratory needs to evaluate carefully the competence of the organization managing the ILC and the suitability of the service externally provided (ISO/IEC 17025 clause 6.6).

Interlaboratory comparisons other than proficiency testing

Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 29th June 2026? Check out new documents from the field of spectroscopy/spectrometry and related techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">LabRulezGCMS</a> libraries.</blockquote>This week we bring you application notes by Agilent Technologies and Thermo Fisher Scientific and brochure by Shimadzu!<h3>1. Agilent Technologies: Analysis of High Purity Titanium Using an <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=9500">Agilent 9500 ICP-QQQ</a></h3>Ensuring purity and performance of titanium materials used in high-tech industries&nbsp;<ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_high_purity_titanium_9500_icp_qqq_5994_9024en_agilent_56ab5e943b.pdf">Full PDF for download</a></li></ul><h5>Importance of high-purity titanium and the role of ICP-QQQ&nbsp;</h5>High-purity titanium (Ti) is a critical material in high-tech industries such as semiconductor manufacturing and aerospace engineering. In semiconductor applications, Ti is widely used as a sputtering target for thin-film deposition, where even trace levels of impurities can negatively affect film uniformity, electrical properties, and device reliability. In aerospace applications, Ti is valued for its high strength-to-weight ratio and corrosion resistance, making it an ideal material for engine components and structural parts. However, any impurities can compromise the mechanical integrity and diminish the long-term performance of components, especially when operating under extreme conditions.Ensuring the reliability and functionality of Ti in these demanding environments requires precise quantification of trace impurities in the raw material. Triple quadrupole Inductively Coupled Plasma Mass Spectrometry (ICP-QQQ) provides robust suppression of spectral interferences and ultra-low detection limits (DLs), enabling accurate determination of impurities at or below the 1 mg/kg (ppm) level in the solid. This level of sensitivity is particularly important for quality control (QC) of high-purity Ti, where conventional techniques such as XRF, ICP-OES, and GD-MS lack the sensitivity and DLs.&nbsp;For unrivalled interference reduction using reactive cell gases, Agilent ICP-QQQ instruments include two unit mass (1 u) quadrupole mass filters, Q1 and Q2.1 Q1 is positioned before the collision/reaction cell (CRC) to select which ions enter the cell for reaction with the cell gas. Q2 filters ions that exit the cell before they pass to the detector. This tandem mass spectrometer (MS/MS) operation allows for unmatched control of reaction chemistry in the CRC, making the technique useful for handling intense spectral interferences, including polyatomic, doubly charged ion (M++), isobaric, and peak overlap interferences.&nbsp;Using the newly developed <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=9500">Agilent 9500 Triple Quadrupole ICP-MS</a> featuring a Dual-Cell System (DCS) CRC and equipped with an optional m-lens, analysts can confidently analyze Ti matrix samples and verify material purity over extended measurement periods. The m-lens is designed with an optimized geometry that minimizes background signals from easily ionized elements that can deposit on interface components during long runs. This feature enables the instrument to maintain high-power, matrix-tolerant plasma conditions while achieving ultralow background equivalent concentrations (BECs), which is critical for ppt-level impurity analysis. Operating the DCS with a suitable cell gas effectively controls spectral interferences from Ti-based species (Ti²+ and TiO+ ) that impact elements like sodium (Na), magnesium (Mg), copper (Cu), and zinc (Zn). Together with the m‑lens, this approach ensures accurate measurement of trace elemental impurities, enabling compliance within stringent industry standards. The effectiveness of the m‑lens in minimizing background signals and enabling ppt‑level impurity analysis under robust plasma conditions has also been demonstrated in high-matrix applications using ICP‑QQQ.2, 3 In addition to interference control, the 9500 ICP-QQQ system’s robustness and reproducibility make it well suited for routine analysis in both research and production settings. This capability supports the continued advancement of high-tech applications that rely on ultra-clean titanium.In this study, a 200 ppm Ti solution prepared from a high-purity Ti powder was used to represent a typical sample encountered in advanced material analysis. The performance of the 9500 ICP-QQQ for quantifying trace impurities, including Na, Mg, Cu, and Zn, in a high Ti matrix was assessed through spike-recovery experiments and long-term stability tests.<h4>Conclusion&nbsp;</h4>This study demonstrated the effectiveness of the Agilent 9500 ICP-QQQ with m-lens for the ultra-trace analysis of impurity metals in high-purity titanium. By applying optimized reaction gas conditions and mass-shift techniques, spectral interferences from Ti-based species such as Ti²+ and TiO+ were successfully mitigated, enabling accurate quantification of elements like Mg, Cu, and Zn.&nbsp;The method achieved limits of quantification in the sub-ppm range for the undiluted Ti digestion solution and maintained stable ISTD signals over extended measurement periods. Spike recovery tests confirmed high accuracy and reproducibility, with most elements showing recoveries within ±10% and RSDs below 3%.&nbsp;These results confirm that the 9500 ICP-QQQ is a robust and reliable tool for quality control of high-purity Ti, supporting its critical applications in semiconductor and aerospace industries where impurity levels must be strictly controlled.<h3>2. Shimadzu: Scanning Probe Microscope /Atomic Force Microscope SPM-9700HT Plus</h3><ul><li>Brochure</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/c147_e021_4c550d3be3.pdf">Full PDF for download</a></li></ul>The Shimadzu SPM-9700HT Plus is a high-throughput scanning probe microscope (SPM) / atomic force microscope (AFM) designed for three-dimensional surface imaging and nanoscale characterization of material properties across a broad range of scientific and industrial applications. The system combines high-resolution topographical imaging with multiple AFM measurement modes, including contact, dynamic, phase, lateral force, force modulation, and force-curve measurements, while optional modules extend its capabilities to techniques such as Kelvin probe force microscopy (KPFM), magnetic force microscopy (MFM), conductive AFM, piezoresponse force microscopy (PFM), and scanning tunneling microscopy (STM). A wide selection of interchangeable scanners, environmental accessories, optical microscope units, and specialized sample holders enables the instrument to be configured for diverse analytical requirements.A major focus of the brochure is the system's emphasis on automation and ease of use through Shimadzu's Analytical Intelligence technology. Features such as Observation Navigation, NanoAssist, and the optional Cantilever Master automate instrument setup, cantilever installation, optimization of imaging parameters, and measurement workflows, allowing operators with varying levels of experience to acquire high-quality, reproducible AFM data. The redesigned control electronics and scanning system also enable high-throughput imaging and rapid physical property mapping while maintaining nanoscale resolution. In addition, the head-slide mechanism simplifies sample exchange without removing the cantilever, increasing productivity during routine measurements.Beyond surface topography, the SPM-9700HT Plus provides extensive quantitative analysis capabilities through integrated software for roughness measurements, particle analysis, cross-sectional profiling, and morphological characterization. Optional Nano 3D Mapping Fast technology extends the instrument to nanoscale mechanical property measurements by performing force-curve mapping, allowing localized evaluation of adhesion, Young's modulus, and other mechanical properties of thin films, polymers, biomaterials, and soft samples. The optional Particle Analysis Software further enables automated extraction, classification, statistical evaluation, and export of particle size and morphology data for large datasets.The brochure demonstrates the versatility of the platform through numerous application examples spanning electronics, semiconductor devices, magnetic materials, life sciences, industrial materials, batteries, polymers, nanomaterials, food science, and chemistry. Representative studies include magnetic domain imaging, organic thin-film transistor characterization, collagen and DNA visualization, live-cell imaging, lithium-ion battery electrode and separator analysis, photocatalyst surface potential measurements, polymer phase imaging, cellulose nanofiber characterization, and beer yeast morphology. Together, these examples highlight the Shimadzu SPM-9700HT Plus as a comprehensive AFM platform capable of combining rapid imaging, advanced nanoscale property mapping, and automated data analysis for both research and routine industrial quality control.<h3>3. Thermo Fisher Scientific: Enhancing Monoclonal Antibody Yield and Quality Through Automated Multi-Component Feedback Control Loops Using the MarqMetrix All-In-One Process Raman Analyzer</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/enhancing_monoclonal_antibody_an1506_en_bba763e865.pdf">Full PDF for download</a></li></ul>The application of Raman spectroscopy for real-time monitoring and control of bioreactors marks a significant advancement in bioprocessing technology. Over the past decade, its adoption has enabled tighter control of critical process parameters (CPPs), offering early indicators of process performance to ensure consistency and improve product quality. Raman spectroscopy leverages the unique vibrational signatures of molecules, allowing for highly specific detection even in complex biological matrices. This enables simultaneous, real-time monitoring of multiple CPPs, including nutrient concentrations, metabolic by-products, and cell density. As a result, users gain deep, real-time insights into cellular metabolism and can implement more dynamic, adaptive feeding strategies based on metabolic network understanding.&nbsp;Previous studies have demonstrated the negative impact of high lactate on cell health and quantity and quality of titer produced.² In this study, we demonstrate the successful implementation of process Raman analyzer for simultaneous multi-component feedback control of glucose and lactate in a bioreactor. By continuously monitoring both analytes, the feedback control loop dynamically maintained a constant total carbon concentration (glucose + lactate) at a setpoint of 2 g/L.&nbsp;This advanced carbon-source-based control strategy ensured that cellular metabolic demands were met while promoting lactate consumption toward the end of the run. As a result, lactate accumulation was significantly reduced, leading to substantial improvements in titer yield, product quality, and cell viability compared to standard bolus feeding strategies (Figure 2).The outcomes of this work underscore the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2233">Thermo Scientific™ MarqMetrix™ All-In-One Process Raman Analyzer </a>as a key Process Analytical Technology (PAT) tool-enabling real-time, multi-analyte control for any biomanufacturer seeking to engage in intelligent, automated biomanufacturing.<h4>Conclusion&nbsp;</h4><h5>1. Unmatched Real-Time Control Capability:&nbsp;</h5>Maintaining a constant total carbon concentration (glucose + lactate) of 2 g/L in dynamic bioreactor environments demands precise, simultaneous analyte monitoring. The MarqMetrix All-In-One Process Raman Analyzer delivers near real-time, high-fidelity data every two minutes, empowering advanced control strategies that are simply not feasible with conventional technologies. This makes it an indispensable PAT tool for modern bioprocessing.&nbsp;<h5>2. Proven Impact on Product Yield and Quality:&nbsp;</h5>The Raman-enabled carbon control strategy resulted in a &gt;10% increase in titer and a reduction in glycation by 83% and 66% compared to continuous and fed-batch glucose control, respectively. These outcomes underscore the analyzer’s transformative impact on both product quantity and quality.&nbsp;<h5>3. Versatile Automation Across Bioprocesses:&nbsp;</h5>All three bioreactor runs—each employing distinct control logics (Table 2)—were successfully managed through automated feedback using the process Raman analyzer. Its flexible design, including easily swappable probes, supports seamless adaptation to other critical metabolites such as amino acids, making it a universal solution for bioprocess control.&nbsp;<h5>4. Foundation for Intelligent Manufacturing:&nbsp;</h5>With its real-time, data-rich insights and seamless integration into automated systems, the MarqMetrix All-InOne analyzer is not just a monitoring tool; it is a cornerstone technology for intelligent, AI-driven biomanufacturing. It enables consistent, high-quality production while reducing time, cost, and variability.

News from LabRulezICPMS Library - Week 27, 2026

Scientists from CEITEC Brno University of Technology led by Markéta Kaiser have achieved a globally unique breakthrough in coral research. Using the live microCT method, they were able, for the first time ever, to observe the growth of living marine corals in real time and reveal the processes behind the formation of their calcium carbonate skeletons, which had previously remained hidden beneath the surface. The results of the international study, published in the prestigious journal Science Advances, show how corals grow, regenerate, and respond to stress and competing organisms.The <a target="_blank" rel="noopener noreferrer" href="https://www.science.org/doi/10.1126/sciadv.aee3183">study</a> was carried out through a collaboration between researchers from Brno, Vienna, and several other international institutions. A key role was played by the X-ray Micro and Nano Computed Tomography Laboratory (CTLAB) at CEITEC BUT, where all the crucial data and three-dimensional coral models were produced. CEITEC also shares both the first and corresponding authorship of the study.“Thanks to live microCT, we were able, for the first time, to observe what happens beneath the surface of a coral skeleton,” explains Markéta Kaiser from CTLAB at CEITEC BUT. “For example, we witnessed situations where a coral, after being attacked by algae, completely halted its normal growth and began building a protective wall around the threatened area. Once the danger had passed, it was able to resume its original growth pattern.”<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_540e183e84.jpeg" alt="CEITEC BUT/Jakub Rozboud: Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life: Markéta Kaiser, CTLAB CEITEC at CEITEC BUT." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_540e183e84.jpeg 235w," sizes="100vw" width="1600" height="1067">The scientists successfully captured coral growth both vertically and horizontally, the formation of protective barriers against competing organisms, and regeneration mechanisms following damage.The research was exceptionally demanding from a technological standpoint. The team had to develop a special system that enabled living corals to be safely scanned directly in seawater. The coral colonies regularly traveled by train from Vienna to Brno for measurements and, after several hours, were transported back to professional aquarium systems in Vienna.“At first, it seemed like a somewhat crazy idea. No one knew whether living corals could withstand repeated scanning,” says Kaiser. “Gradually, however, we found that they survived, continued to grow, and provided us with unique data.”<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_2_fcbb29a4f6.jpeg" alt="CEITEC BUT/Jakub Rozboud: Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life: Markéta Kaiser is placing a coral sample into CT for scanning." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_2_fcbb29a4f6.jpeg 235w," sizes="100vw" width="1600" height="1067">The original concept for the project came from developmental biologist Igor Adameyko of the Medical University of Vienna, who proposed combining marine biology with advanced imaging technologies more commonly used in engineering and technical fields.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_3_8c5f376f41.jpeg" alt="CEITEC BUT/Markéta Kaiser: Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life: Corals CT - 1." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_3_8c5f376f41.jpeg 228w," sizes="100vw" width="1600" height="1096">The findings of the Brno researchers have already attracted the attention of experts in Okinawa, Japan, who specialize in coral reef research. They plan to use the live microCT method to study the effects of light, photosynthesis, and environmental changes on coral growth.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_4_445c1cc3b7.jpeg" alt="CEITEC BUT/Markéta Kaiser: Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life:Corals CT - 2." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_4_445c1cc3b7.jpeg 245w," sizes="100vw" width="1600" height="988">According to the researchers, the project demonstrates the importance of interdisciplinary collaboration between engineering and biological sciences. The research could contribute not only to the study and conservation of coral reefs, but also to fields such as paleontology and materials science.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_5_514ee9c974.jpg" alt="CEITEC BUT/Markéta Kaiser: Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life: Corals CT - 3." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_5_514ee9c974.jpg 143w," sizes="100vw" width="1600" height="1750"><blockquote><h4>Original Article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://www.science.org/doi/10.1126/sciadv.aee3183">Coral growth, retraction, defense, and regenerative strategies revealed by live microCT</a></h4>Karina Araslanova, Marketa Kaiser, Anton Fetisov, Diana Gavrik, Tomas Zikmund, Daniel Abed-Navandi, Karel Katovský, Jozef Kaiser, Igor AdameykoSci. Adv., 2026, 12, eaee3183<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1126/sciadv.aee3183">https://doi.org/10.1126/sciadv.aee3183</a><h6>licenced under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote><h4>Abstract</h4>Understanding how corals build and remodel their skeletons is key to explaining reef resilience, yet most insights come from static imaging. Using longitudinal live microCT, we tracked the same coral colonies over weeks to months at micrometer resolution. Coral skeleton formation is not a uniform accretion process but a dynamic integration of multiple programs, including vertical and horizontal patterned growth, previously undescribed defensive wall-building against competitors, exploratory edge behavior with reversible expansions and retractions, and skeletal regeneration favoring rapid, imprecise yet effective matrix expansion. Time-resolved imaging links colony-scale growth to microscale events, showing that all modes depend on balances between fusion of skeletal microparticles and layered matrix deposition, guided by tissue prepatterning. Beyond corals, this framework generalizes to studying skeletal dynamics across diverse biomineralizing organisms.

Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life 

Article

Application

Academy

Science and research

Since its establishment in 2011, CEITEC has quickly developed into a cutting-edge infrastructure for research which performs highly alongside the best institutes in Europe. Among the main priorities of CEITEC are the promotion of a motivating and dynamic international scientific environment, the provision of state-of-the-art research infrastructure, and the policy of open communication and equal opportunities.

CEITEC

Eurachem is a European network promoting international traceability of chemical measurements and good analytical practice. It provides expert guidance, supports method validation, uncertainty evaluation, proficiency testing, and facilitates discussion on technical and policy issues in analytical quality.

Eurachem

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

NenoVision

Zeiss Group

Agilent Technologies

Bruker

SelectScience

Wiley

Shimadzu Corporation

MP-AES is suitable instrument for the multi-elemental analysis of a wide range of sample types, including complex organic matrices, and with the lowest cost of ownership.
Faster, easy to use and with better performance than Atomic Absorption Spectroscopy (AA), in this seminar we will review the technology and the applications that can be easily resolved by MP-AES.
<blockquote>
Presenter: Ana García González (Atomic Spectroscopy Application Scientist, Agilent Technologies)
</blockquote>
<blockquote>
Ana Garcia is the Atomic Spectroscopy Application Scientist at Agilent Technologies. Ana has a broad background in atomic spectroscopy technologies, including international experience developing and validating analytical spectroscopy methods for the geochemical industry. She has also published in the fields of molecular spectroscopy and chemometrics. Ana holds a MSc in plant Biotechnology at CINVESTAV, México, and a Bachelor of Science in Biotechnology Engineering.
</blockquote>

Agilent Technologies: Achieve better productivity in your elemental analysis: Switch from Flame Atomic Absorption (AAS) to MPAES

Achieve better productivity in your elemental analysis: Switch from Flame Atomic Absorption (AAS) to MPAES

The technology and the applications that can be easily resolved by MP-AES.

Switch from Flame Atomic Absorption (AAS) to MPAES

Advanced materials are increasingly finding uses in the worlds of wafers and photovoltaic materials.
As they are being developed, there is a need to understand their optical properties. How much light is being reflected/transmitted/adsorbed and how the polarization of light effects these values gives insight into the materials’ potential performance in devices. This talk will examine how angular measurements can be made through the use of a Cary 7000 and its UMA (Universal Measurement Accessory).
<blockquote>
Presenter: Mark Fisher, PhD (Application Engineer, Molecular Spectroscopy, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Mark, an Application Scientist for Agilent Technologies, has over 35 years of experience in molecular spectroscopy. He has held roles in Agilent&#39;s UV-Vis-NIR, fluorescence, and atomic absorption product portfolios. In addition to identifying industry trends and new business needs, Mark&#39;s responsibilities include application development, pre and post-sales support, as well as acting as a customer advocate for new product and technology opportunities. Mark received his doctorate in analytical chemistry from the University of Nebraska-Lincoln.
</blockquote>

Agilent Technologies: Determination of Optical Properties of Advanced Materials through Angular UV-Vis-NIR Measurements

Determination of Optical Properties of Advanced Materials through Angular UV-Vis-NIR Measurements

How angular measurements can be made through the use of a Cary 7000 and its UMA (Universal Measurement Accessory).

Determination of Optical Properties of Advanced Materials

The widespread challenge posed by microplastics is a pressing issue that necessitates innovative solutions.
In this Digital Classrooms session, explore how Shimadzu&#39;s state-of-the-art analytical and measuring instruments are leading the way in microplastics research, analysis, and characterization.
In the first part of the session, we will explore the analysis of microplastics in oceans and other environmental waters using Fourier-Transform Infrared Spectroscopy (FTIR) and Infrared/Raman microscope. Learn how these tools, combined with our innovative automated sample preparation device and the resourceful degraded plastics libraries, can accurately identify and characterize microplastics, contributing to a more profound comprehension of their prevalence in aquatic ecosystems.
In the second part, we&#39;ll unveil an automated workflow leveraging Pyrolysis-Gas Chromatography/Mass Spectrometry (Pyrolysis-GCMS). This cutting-edge approach streamlines the identification and quantitative analysis of microplastics in environmental samples, increasing efficiency while maintaining accuracy.
Join us to explore how Shimadzu&#39;s solutions are meeting the needs of today – Be part of the change and understand how we can overcome this environmental challenge together.
Learning Objectives:
<ul>
<li>Explore Shimadzu&#39;s analytical tools for microplastics research and analysis
</li>
<li>Understand use of FTIR and Infrared/Raman microscopy in microplastics identification
</li>
<li>Learn how to streamline identification and quantification of microplastics using Pyrolysis-GCMS
</li>
<li>Discover how automated workflows enhance efficiency in microplastics analysis in environmental samples
</li>
</ul>
<blockquote>
Presenter: Pravin Konde, PhD (Senior Product Specialist, Shimadzu (Asia Pacific) Pte Ltd)
</blockquote>
<blockquote>
Pravin Konde is a Senior Product Specialist (for Spectroscopy &amp; TOC) at Shimadzu Asia Pacific Singapore. He has about 15 years of industry experience of which about 12 years in analytical instruments with expertise in trace element analysis and spectroscopy applications. He is engaged primarily in technical support to regional sales teams and customers. Prior to joining industry, he has done his PhD in Chemistry from Institute of Chemical Technology (formerly UDCT), Mumbai, India.
</blockquote>
<blockquote>
Presenter: Chua Chun Kiang, PhD (Senior Product Specialist (GCMS), Shimadzu (Asia Pacific) Pte Ltd)
</blockquote>
<blockquote>
Chun Kiang received his Ph.D. in Chemistry from Nanyang Technological University, Singapore. He has been at Shimadzu Asia Pacific since 2019. He has more than 10 years of experience in research and training across multiple disciplines including mass spectrometry, gas and liquid chromatography, nanomaterials, electrochemistry, and organic chemistry. He enjoys sharing technical knowledge and helping to identify solutions for challenges in chemistry.
</blockquote>

Shimadzu: Fast-Track Microplastics Research: Advanced, Automated Workflows For Environmental Analysis

Fast-Track Microplastics Research: Advanced, Automated Workflows For Environmental Analysis

Explore how Shimadzu's state-of-the-art analytical and measuring instruments are leading the way in microplastics research, analysis, and characterization.

Microplastics: Workflows For Environmental Analysis

In this Webinar Thomas Spengler will explain the importance of protecting the beekeepers and the bees, as many food products we eat depend on pollination by the bees. Beekeepers are suffering from adulteration in many countries, and it is a real threat to their existence and the food security. Also, consumers are denied the health benefits, which is only given when honey is pure and is produced completely by the bees.
Martin Linkogel from Quality Services International Laboratory will talk about the application of H-NMR and the Honey Profiling 3.1 Method in daily routine for authenticity and quality analysis of honey.
<h5>Key Learning Topics</h5>
<ul>
<li>The various modes of adulteration on honey and the need for advanced for multi marker and non-targeted techniques to tackle honey fraud, ensure supply chain integrity and protect beekeepers, packers and consumers.
</li>
<li>Description of NMR as a powerful technique for the analysis of food products.
</li>
<li>The use of NMR for verification of the declared geographical origin and botanical variety.
</li>
<li>How QSI uses H-NMR and the Bruker Honey Profiling Method 3.1 to universally and efficiently tackle unknown foreign sugar syrups in honey via the targeted detection of sugar syrup markets and non-targeted via dilution effects in the spectra.
</li>
<li>Effective syrup detection (C3 and C4 sugars) in routine quality control: exemplary result comparison for Honey Authenticity Triple-Screening by NMR Bruker, HRMS and LC-IRMS.
</li>
<li>Comparability of NMR Bruker results and judgement between different labs in the view of QSI as quality control lab.
</li>
</ul>
<h5>What to Expect</h5>
<ul>
<li>Insight into the Honey-Profiling method and the new features of version 3.1
</li>
<li>Understanding of the unique advantages of the method over other analytical methods.
</li>
</ul>
<blockquote>
Presenter: Thomas Spengler (Director Market Management Food Feed Beverages &amp; Head of Lean Customer Development, AIC Division, Bruker BioSpin GmbH)
</blockquote>
<blockquote>
Thomas holds a master&#39;s degree from Technical University Munich in food engineering and he is in charge of the Food, Feed &amp; Beverage markets. His main focus is to support the business growth, identify new markets and segments and translate the voice of the customers into new solutions which address their needs.
</blockquote>
<blockquote>
Presenter: Martin Linkogel (Authorized Representative of General Management and Business Unit Manager Bee Products, Quality Services International GmbH, QSI Bremen, Germany)
</blockquote>
<blockquote>
Martin Linkogel is Certified Food Chemist (University of Hamburg, Germany, 1999) and has more than 23 years professional experience in instrumental analytical chemistry in the food and pharma industry. Since 2007 he focusses on all different aspects of the quality control of honey and bee products, from honey authenticity testing to residues of veterinary drugs.
</blockquote>
<blockquote>
After working as head of the laboratory at Applica/Intertek (Bremen) for nearly 10 years, he joined QSI Bremen in 2017 and manages the honey business unit including the development and harmonization of test methods, especially in the field of authenticity testing. He technically advises customers in setting up efficient, risk-based quality control strategies including the application of the most sophisticated test methods like NMR, HRMS, LC-MS/MS and LC-IRMS.
</blockquote>
<blockquote>
QSI Bremen is a leading independent quality control laboratory working as reliable partner for the customers worldwide. QSI Bremen is full member of the Bruker NMR Honey ProfilingTM consortium since the beginning and significantly contributed to the establishment of the NMR Bruker database.
</blockquote>

Bruker: Bee or not to be? Is your honey authentic?

Bee or not to be? Is your honey authentic?

The webinar will discuss the application of H-NMR and the Honey Profiling 3.1 Method in daily routine for authenticity and quality analysis of honey.

Is your honey authentic? NMR and the Honey Profiling

Hydrogen is one of the most promising energy carriers that can enable a low-carbon economy.
In this webinar, Maria Lyubimova, Hydrogen business development manager, HORIBA France, will discuss solutions for the full development and manufacturing lifecycle that are enabling a global adoption of hydrogen technologies.
Gain insight into how HORIBA is providing innovative development tools to help accelerate the adoption of hydrogen technologies. These tools allow engineers, researchers, and scientists to address tomorrow’s challenges and to improve performance, quality, and cost. Furthermore, explore HORIBA’s large panel of techniques such as Raman, fluorescence, glow discharge, particle size, ICP, AFM, ellipsometry, C/S and O/N/H analyzers, and impedance spectroscopy.
Key learning objectives
<ul>
<li>Learn more about the qualification of raw materials
</li>
<li>Understand cell and stack components research and development
</li>
<li>Learn more about the validation of processed materials
</li>
</ul>
Who should attend?
<ul>
<li>Scientists and engineers conducting R&amp;D on cells and components like bi-polar plates, gas diffusion layers, and membrane electrode assemblies for electrolysis.</li>
</ul>
<blockquote>
Presenter: Maria Lyubimova (Hydrogen business development manager, HORIBA France)
</blockquote>

SelectScience: Testing and measurement solutions for hydrogen technologies

Testing and measurement solutions for hydrogen technologies

Solutions for the full development and manufacturing lifecycle that are enabling a global adoption of hydrogen technologies.

Wiley’s KnowItAll spectral software offers solutions to identify, analyze, and manage analytical data (IR, MS, NMR, Raman, and UV-Vis). Combined with Wiley’s comprehensive, high-quality spectral reference libraries, it provides an unparalleled solution for fast, reliable spectral analysis.
With the KnowItAll 2024 software release, Wiley continues to expand KnowItAll’s capabilities, including an integrated tool for multi-technique quantitative analysis that can greatly streamline your workflow; plus, many enhancements and upgrades to data management, processing, and reporting. In this release, we have also made advances to our NMR workflow and LC-MS databasing.
In this webinar, we will review the latest features and how they can impact your research and analyses.
<blockquote>
Presenter: Dr. Michelle D’Souza, Ph.D. (Product Manager, Software Products, Wiley Science Solutions)
</blockquote>
<blockquote>
Dr. D’Souza brings years of insight and knowledge in the area of spectral informatics with leadership roles at Wiley and Bio-Rad Laboratories. In addition to multiple years as a scientific researcher at Abbott (now AbbVie) and DuPont. She has a Ph.D. in Chemistry from Northern Illinois University and a Masters in Analytical Chemistry form the Chinese Academy of Preventative Medicine. She earned a BS degree from the Chemistry Department of Beijing University.
</blockquote>

What's New in KnowItAll 2024

The latest features and how they can impact your research and analyses.

Discover the interdependent relationship between the structure, properties, and performance of drugs in pharmaceutical material science.
In this webinar, Dr. Ben Tordoff, Head of Materials Science Business Sector at ZEISS Research Microscopy Solutions, Parmesh Gajar, principal scientist at the University of Manchester and Darragh Murnane, Professor of Pharmaceutics at the University of Hertfordshire will discuss the importance of the microstructure for producing respirable particles for effective therapeutic benefits of a typical dry powder inhaler (DPI) formulation.
Additionally, they will describe how X-ray microscopy (XRM) can be combined with molecular modeling to calculate inter-particulate forces that underpin powder cohesion. They will also explain how the LabDCT technique can be utilized to gather 3D crystallographic information on crystalline bulk powders of lactose particles.
Finally, they will illustrate how artificial intelligence (AI) image analysis is used to visualize the powder microstructure and simulate the drug release performance.
Key learning objectives:
<ul>
<li>Learn how to evaluate heterogeneous microstructures
</li>
<li>Discover how to combine crystallographic information and micro-CT imaging
</li>
<li>Understand why drug delivery is dependent on the microstructure and how it can be simulated
</li>
</ul>
Who should attend?
Materials researchers from academia and industry, X-ray microscopy users, drug designers, pharmaceuticals material researchers, PhD students, principal investigators, and lab managers.
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
<blockquote>
Presenter: Dr. Ben Tordoff (ZEISS Research Microscopy Solutions)
</blockquote>
<blockquote>
Dr. Ben Tordoff is the head of materials science at ZEISS Research Microscopy where he leads a team of materials scientists to develop workflows, applications and hardware for the next generation of scientists. He received his master&#39;s in physics and his PhD in experimental nuclear physics from the University of Manchester, UK, where he was awarded a Marie Curie scholarship. After graduation, he worked in several roles in R&amp;D, project management, product management and strategic marketing.
</blockquote>
<blockquote>
Presenter: Darragh Murnane (University of Hertfordshire)
</blockquote>
<blockquote>
Darragh Murnane is professor of pharmaceutics, an associate dean for business and enterprise at the University of Hertfordshire, UK, and a member of the MHRA’s expert advisory group on chemistry, pharmacy and standards. He leads research programs in medicinal product design and manufacture, biological models of disease and drug bioanalysis, and the design and use of inhalation devices. Since 2016, he has collaborated with Prof Phil Withers of the UK’s National X-ray Computed Tomography Facility at the University of Manchester to research X-ray CT methodologies for pharmaceuticals. In July 2023, Prof. Murnane founded Informix Pharma Ltd.
</blockquote>
<blockquote>
Presenter: Lawrence Howes (SelectScience)
</blockquote>
<blockquote>
Lawrence studied biological sciences at Swansea University, UK, before completing a master’s in epidemiology at the University of Bristol. As a member of the Editorial team, he now plays an integral role in shaping the content on SelectScience
</blockquote>

SelectScience: Quantitative characterization of asthma inhalation blends using correlative, AI powered X-ray microscopy

Quantitative characterization of asthma inhalation blends using correlative, AI powered X-ray microscopy

Characterizing asthma inhaler blends using AI powered X-ray

The digital lab is more than a vision. Agilent offers everything you need to accelerate your journey to peak efficiency—today.
There is no question that recent technologies can dramatically improve efficiency and scientific insights for analytical labs. Automation, artificial intelligence, robotic systems, virtual reality, informatics, advanced algorithms, and consistent data structures all hold promise for increasing lab throughput, reducing errors, and cutting costs.
The new question is how to transform your vision of the digital lab into reality—quickly, cost-efficiently, and with a strong partner you can trust. Agilent has the open solutions, the modern technology, and the proven track record you need to accelerate your journey with confidence. Let us explore the opportunities together.
<h4>In this webinar, you will understand 3 focus area:</h4>
1. Data Optimization - To get the answers lab managers and data scientists need faster using informatics, analytics, AI and more.
2. Enterprise Optimization - To drive down operational costs through cloud operations, security, and resource management.
3. Lab Optimization - To increase yield, quality, and throughput via digital services, workflow orchestration, and lab automation.
 Who should attend?
This webinar is exclusively meant for executives, heads, managers and decision makers who are looking forward to making the lab environment more digital and paperless. This webinar content is suitable for Pharmaceuticals/ Biopharmaceuticals/ Food testing &amp; Chemical industry R&amp;D/ ADL/ QC/ QA/ IT etc.
<blockquote>
Presenter: Amit Ghate (Application Specialist - Lab Informatics, Agilent Technologies)
Amit Ghate is currently working as Lab Informatics Application Specialist at Agilent Technologies. Amit comes from analytical software background where he has an in-depth knowledge of variety of software like Chromatography Data Systems, Data Management, LIMS, Electronic Lab Notebook, databases, reports and Compliance. Prior to joining Agilent, Amit worked with Persistent Systems Ltd as a Project Manager for software support and services. He has done his Masters in Bioinformatics from University of Pune. His main areas of interest is in providing workflow solutions and enabling digital transformation of labs.
</blockquote>

Agilent India: Transforming your Lab to Digital & Paperless

Transforming your Lab to Digital & Paperless

Automation, artificial intelligence, robotic systems, virtual reality, informatics, advanced algorithms, and consistent data structures in the lab.

ZEISS Microscopy Solutions cover all tasks in Materialography: From routine applications to complex failure analysis. Hardware and software interact effectively so that all inspection tasks that arise can be solved easily.
Highlights of this webinar:
<ul>
<li>Meeting challenges in Materialography with machine learning.
</li>
<li>Optimizing the workflow with intelligent tools from ZEISS.
</li>
<li>Application examples from industry, for industry.
</li>
</ul>

Zeiss: Materials get complex. Analysis gets simple.

Materials get complex. Analysis gets simple.

Battery materials are key to revolutionizing energy storage technologies, making it crucial to explore their characteristics at macro and nanoscale levels. Join us for an webinar as we delve into the world of battery materials analysis.
Webinar Highlights:
Understanding batteries inside out: Characterizing batteries and their individual components (cathodes, electrolytes, anodes, and SEI) is indispensable for the development of advanced energy storage solutions. Explore how degradation processes transform these components during cycling and gain a profound insight into the mechanisms influencing battery lifetime and performance. We will explain and demonstrate how multiple techniques, such as SEM, EDX, and AFM, bring significant benefits for battery materials characterization.
During the webinar, you will learn:
<ul>
<li>Key challenges in the characterization of batteries and their components and how AFM-in-SEM technology resolves them.
</li>
<li>Efficient sample preparation workflow of extremely air-sensitive battery samples, their cross-sectioning, and sample transfer to integrated AFM/SEM/EDX instrument.
</li>
<li>Application examples of in-situ correlative microscopy analysis of various cathode materials (NCM, NCA) in pristine and cycled stages. We will demonstrate how AFM-in-SEM is used to understand the degradation process inside the cathodes.
</li>
</ul>
Why Attend?
<ul>
<li>Gain insights into the critical challenges of battery materials characterization.
</li>
<li>Learn how AFM-in-SEM technology can address these challenges effectively.
</li>
<li>Discover efficient sample preparation techniques for air-sensitive battery materials.
</li>
<li>Explore application examples of in-situ correlative microscopy.
</li>
<li>Understand the role of AFM-in-SEM in deciphering cathode degradation processes.
</li>
</ul>
The expected duration is about 45 minutes. The invitations with the link to live streaming will be sent after the registration. The webinar is entirely free.
<blockquote>
Presenter: Tomáš Kazda (Chairman of Czech Battery Cluster and Associate Professor at BUT)
</blockquote>
<blockquote>
Presenter: Jan Neuman (CEO &amp; Co-founder at NenoVision)
</blockquote>

NenoVision: Unlocking the Secrets of Battery Materials: A Dive into AFM-in-SEM Characterization