The international standard ISO/IEC 17025 [1] clause 7.7.2 with regards to ensuring the validity of results, requires a laboratory to participate in proficiency testing (PT) and/or to participate in interlaboratory comparisons (ILCs) other than PT. However, no guidance as to what these other ILCs might be, or indeed how they might compare in relation to PT, is provided. This leaflet aims to outline other ILCs available, pointing out some of the limitations as compared to PT.&nbsp;There are three major types of ILCs in which a group of laboratories analyses identical portions from a homogeneous, stable test sample, with each type being characterized by its intended purpose [2,3]:<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Interlaboratory_comparisons_other_than_proficiency_testing_2_d9263807fb.jpg" alt="Eurachem: Interlaboratory comparisons other than proficiency testing" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Interlaboratory_comparisons_other_than_proficiency_testing_2_d9263807fb.jpg 245w," sizes="100vw" width="1507" height="607">A key point is that PT is an ILC that is designed to specifically evaluate the performance of participants, providing them with an infrastructure to monitor and assess the validity of their results. This is not the key purpose of the two other ILCs, and thus depending on their intended purpose they have a number of limitations that laboratories need to be aware of when using them rather than PT. Only proficiency testing should have been conducted in full compliance to the competency standard ISO/IEC 17043 [4].&nbsp;<h4>Evaluation of measurement procedure performance&nbsp;</h4>These ILCs, are designed to assess how a particular measurement procedure performs and whether it is fit for its intended purpose. These ILCs are often referred to as a ‘method performance study’ or a ‘collaborative study’ [2]. Some limitations of using such ILCs for monitoring laboratory performance as an alternative to PT are:&nbsp;<ul><li>All participants use the same measurement procedure i.e. the measurement procedure that is being validated. Unless the measurement procedure is being routinely used by the participating laboratory such an ILC will not assess the routine performance of the laboratory using their own routine measurement procedure. Nor does it enable them to compare their performance with other laboratories using alternative measurement procedures.&nbsp;</li><li>The measurement procedure is likely to be new, so participants may not have established stable procedures and quality control, so performance may not reflect routine use.&nbsp;</li><li>The report from such an ILC would not provide information on the performance of the participant, if the statistical model used makes the assumption that all laboratories perform with equal variability.</li><li>The design of the study may require the participants to assess multiple samples and/or to undertake multiple replicate analysis on the test materials. This may not be representative of the routine measurements or tests undertaken by the laboratory.&nbsp;</li><li>The conclusion of the ILC might be that the measurement procedure being assessed is not valid.&nbsp;</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Interlaboratory_comparisons_other_than_proficiency_testing_3_a53ecd2f5d.jpg" alt="Eurachem: Interlaboratory comparisons other than proficiency testing" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Interlaboratory_comparisons_other_than_proficiency_testing_3_a53ecd2f5d.jpg 157w," sizes="100vw" width="570" height="566"><h4>Characterisation of candidate reference materials&nbsp;</h4>These are ILCs that assign a property value to a candidate reference material, usually with a stated measurement uncertainty. These are often referred to as a ‘material certification study’ [2]. Limitations of using such ILCs as an alternative to PT are:&nbsp;<ul><li>The analysis of the candidate reference material is likely to require additional care in exercising the routine measurement procedure, such as substantially more replication, and/or may require quite different reporting formats (e.g. all valid replicates instead of a mean result). Thus, such an ILC will not necessarily provide an evaluation of the performance of the laboratory based on the routine use of their measurement procedures.&nbsp;</li><li>The report from such an ILC may include the results from the participating laboratories but would not provide information on the performance of each laboratory.&nbsp;</li><li>Participating laboratories may be required to assess multiple samples and/or to undertake multiple replicate analysis on the candidate reference materials. Thus this may not be representative of the routine measurements or tests undertaken by the laboratory.&nbsp;</li></ul><h4>Other ILCs&nbsp;</h4>Some other ILCs, whilst not being conducted in full compliance of the requirements of ISO/IEC 17043, may be designed to evaluate participant performance. These would include small ILCs as defined by EA‑2/21 [5] or split sample ILCs i.e. where a portion of a single sample is sent to two or three laboratories. Whilst these ILCs are specifically designed to evaluate participant performance, they may not provide a comprehensive comparison that a PT might provide. In such cases the laboratory needs to evaluate carefully the competence of the organization managing the ILC and the suitability of the service externally provided (ISO/IEC 17025 clause 6.6).

Interlaboratory comparisons other than proficiency testing

Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 29th June 2026? Check out new documents from the field of spectroscopy/spectrometry and related techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">LabRulezGCMS</a> libraries.</blockquote>This week we bring you application notes by Agilent Technologies and Thermo Fisher Scientific and brochure by Shimadzu!<h3>1. Agilent Technologies: Analysis of High Purity Titanium Using an <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=9500">Agilent 9500 ICP-QQQ</a></h3>Ensuring purity and performance of titanium materials used in high-tech industries&nbsp;<ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_high_purity_titanium_9500_icp_qqq_5994_9024en_agilent_56ab5e943b.pdf">Full PDF for download</a></li></ul><h5>Importance of high-purity titanium and the role of ICP-QQQ&nbsp;</h5>High-purity titanium (Ti) is a critical material in high-tech industries such as semiconductor manufacturing and aerospace engineering. In semiconductor applications, Ti is widely used as a sputtering target for thin-film deposition, where even trace levels of impurities can negatively affect film uniformity, electrical properties, and device reliability. In aerospace applications, Ti is valued for its high strength-to-weight ratio and corrosion resistance, making it an ideal material for engine components and structural parts. However, any impurities can compromise the mechanical integrity and diminish the long-term performance of components, especially when operating under extreme conditions.Ensuring the reliability and functionality of Ti in these demanding environments requires precise quantification of trace impurities in the raw material. Triple quadrupole Inductively Coupled Plasma Mass Spectrometry (ICP-QQQ) provides robust suppression of spectral interferences and ultra-low detection limits (DLs), enabling accurate determination of impurities at or below the 1 mg/kg (ppm) level in the solid. This level of sensitivity is particularly important for quality control (QC) of high-purity Ti, where conventional techniques such as XRF, ICP-OES, and GD-MS lack the sensitivity and DLs.&nbsp;For unrivalled interference reduction using reactive cell gases, Agilent ICP-QQQ instruments include two unit mass (1 u) quadrupole mass filters, Q1 and Q2.1 Q1 is positioned before the collision/reaction cell (CRC) to select which ions enter the cell for reaction with the cell gas. Q2 filters ions that exit the cell before they pass to the detector. This tandem mass spectrometer (MS/MS) operation allows for unmatched control of reaction chemistry in the CRC, making the technique useful for handling intense spectral interferences, including polyatomic, doubly charged ion (M++), isobaric, and peak overlap interferences.&nbsp;Using the newly developed <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=9500">Agilent 9500 Triple Quadrupole ICP-MS</a> featuring a Dual-Cell System (DCS) CRC and equipped with an optional m-lens, analysts can confidently analyze Ti matrix samples and verify material purity over extended measurement periods. The m-lens is designed with an optimized geometry that minimizes background signals from easily ionized elements that can deposit on interface components during long runs. This feature enables the instrument to maintain high-power, matrix-tolerant plasma conditions while achieving ultralow background equivalent concentrations (BECs), which is critical for ppt-level impurity analysis. Operating the DCS with a suitable cell gas effectively controls spectral interferences from Ti-based species (Ti²+ and TiO+ ) that impact elements like sodium (Na), magnesium (Mg), copper (Cu), and zinc (Zn). Together with the m‑lens, this approach ensures accurate measurement of trace elemental impurities, enabling compliance within stringent industry standards. The effectiveness of the m‑lens in minimizing background signals and enabling ppt‑level impurity analysis under robust plasma conditions has also been demonstrated in high-matrix applications using ICP‑QQQ.2, 3 In addition to interference control, the 9500 ICP-QQQ system’s robustness and reproducibility make it well suited for routine analysis in both research and production settings. This capability supports the continued advancement of high-tech applications that rely on ultra-clean titanium.In this study, a 200 ppm Ti solution prepared from a high-purity Ti powder was used to represent a typical sample encountered in advanced material analysis. The performance of the 9500 ICP-QQQ for quantifying trace impurities, including Na, Mg, Cu, and Zn, in a high Ti matrix was assessed through spike-recovery experiments and long-term stability tests.<h4>Conclusion&nbsp;</h4>This study demonstrated the effectiveness of the Agilent 9500 ICP-QQQ with m-lens for the ultra-trace analysis of impurity metals in high-purity titanium. By applying optimized reaction gas conditions and mass-shift techniques, spectral interferences from Ti-based species such as Ti²+ and TiO+ were successfully mitigated, enabling accurate quantification of elements like Mg, Cu, and Zn.&nbsp;The method achieved limits of quantification in the sub-ppm range for the undiluted Ti digestion solution and maintained stable ISTD signals over extended measurement periods. Spike recovery tests confirmed high accuracy and reproducibility, with most elements showing recoveries within ±10% and RSDs below 3%.&nbsp;These results confirm that the 9500 ICP-QQQ is a robust and reliable tool for quality control of high-purity Ti, supporting its critical applications in semiconductor and aerospace industries where impurity levels must be strictly controlled.<h3>2. Shimadzu: Scanning Probe Microscope /Atomic Force Microscope SPM-9700HT Plus</h3><ul><li>Brochure</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/c147_e021_4c550d3be3.pdf">Full PDF for download</a></li></ul>The Shimadzu SPM-9700HT Plus is a high-throughput scanning probe microscope (SPM) / atomic force microscope (AFM) designed for three-dimensional surface imaging and nanoscale characterization of material properties across a broad range of scientific and industrial applications. The system combines high-resolution topographical imaging with multiple AFM measurement modes, including contact, dynamic, phase, lateral force, force modulation, and force-curve measurements, while optional modules extend its capabilities to techniques such as Kelvin probe force microscopy (KPFM), magnetic force microscopy (MFM), conductive AFM, piezoresponse force microscopy (PFM), and scanning tunneling microscopy (STM). A wide selection of interchangeable scanners, environmental accessories, optical microscope units, and specialized sample holders enables the instrument to be configured for diverse analytical requirements.A major focus of the brochure is the system's emphasis on automation and ease of use through Shimadzu's Analytical Intelligence technology. Features such as Observation Navigation, NanoAssist, and the optional Cantilever Master automate instrument setup, cantilever installation, optimization of imaging parameters, and measurement workflows, allowing operators with varying levels of experience to acquire high-quality, reproducible AFM data. The redesigned control electronics and scanning system also enable high-throughput imaging and rapid physical property mapping while maintaining nanoscale resolution. In addition, the head-slide mechanism simplifies sample exchange without removing the cantilever, increasing productivity during routine measurements.Beyond surface topography, the SPM-9700HT Plus provides extensive quantitative analysis capabilities through integrated software for roughness measurements, particle analysis, cross-sectional profiling, and morphological characterization. Optional Nano 3D Mapping Fast technology extends the instrument to nanoscale mechanical property measurements by performing force-curve mapping, allowing localized evaluation of adhesion, Young's modulus, and other mechanical properties of thin films, polymers, biomaterials, and soft samples. The optional Particle Analysis Software further enables automated extraction, classification, statistical evaluation, and export of particle size and morphology data for large datasets.The brochure demonstrates the versatility of the platform through numerous application examples spanning electronics, semiconductor devices, magnetic materials, life sciences, industrial materials, batteries, polymers, nanomaterials, food science, and chemistry. Representative studies include magnetic domain imaging, organic thin-film transistor characterization, collagen and DNA visualization, live-cell imaging, lithium-ion battery electrode and separator analysis, photocatalyst surface potential measurements, polymer phase imaging, cellulose nanofiber characterization, and beer yeast morphology. Together, these examples highlight the Shimadzu SPM-9700HT Plus as a comprehensive AFM platform capable of combining rapid imaging, advanced nanoscale property mapping, and automated data analysis for both research and routine industrial quality control.<h3>3. Thermo Fisher Scientific: Enhancing Monoclonal Antibody Yield and Quality Through Automated Multi-Component Feedback Control Loops Using the MarqMetrix All-In-One Process Raman Analyzer</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/enhancing_monoclonal_antibody_an1506_en_bba763e865.pdf">Full PDF for download</a></li></ul>The application of Raman spectroscopy for real-time monitoring and control of bioreactors marks a significant advancement in bioprocessing technology. Over the past decade, its adoption has enabled tighter control of critical process parameters (CPPs), offering early indicators of process performance to ensure consistency and improve product quality. Raman spectroscopy leverages the unique vibrational signatures of molecules, allowing for highly specific detection even in complex biological matrices. This enables simultaneous, real-time monitoring of multiple CPPs, including nutrient concentrations, metabolic by-products, and cell density. As a result, users gain deep, real-time insights into cellular metabolism and can implement more dynamic, adaptive feeding strategies based on metabolic network understanding.&nbsp;Previous studies have demonstrated the negative impact of high lactate on cell health and quantity and quality of titer produced.² In this study, we demonstrate the successful implementation of process Raman analyzer for simultaneous multi-component feedback control of glucose and lactate in a bioreactor. By continuously monitoring both analytes, the feedback control loop dynamically maintained a constant total carbon concentration (glucose + lactate) at a setpoint of 2 g/L.&nbsp;This advanced carbon-source-based control strategy ensured that cellular metabolic demands were met while promoting lactate consumption toward the end of the run. As a result, lactate accumulation was significantly reduced, leading to substantial improvements in titer yield, product quality, and cell viability compared to standard bolus feeding strategies (Figure 2).The outcomes of this work underscore the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2233">Thermo Scientific™ MarqMetrix™ All-In-One Process Raman Analyzer </a>as a key Process Analytical Technology (PAT) tool-enabling real-time, multi-analyte control for any biomanufacturer seeking to engage in intelligent, automated biomanufacturing.<h4>Conclusion&nbsp;</h4><h5>1. Unmatched Real-Time Control Capability:&nbsp;</h5>Maintaining a constant total carbon concentration (glucose + lactate) of 2 g/L in dynamic bioreactor environments demands precise, simultaneous analyte monitoring. The MarqMetrix All-In-One Process Raman Analyzer delivers near real-time, high-fidelity data every two minutes, empowering advanced control strategies that are simply not feasible with conventional technologies. This makes it an indispensable PAT tool for modern bioprocessing.&nbsp;<h5>2. Proven Impact on Product Yield and Quality:&nbsp;</h5>The Raman-enabled carbon control strategy resulted in a &gt;10% increase in titer and a reduction in glycation by 83% and 66% compared to continuous and fed-batch glucose control, respectively. These outcomes underscore the analyzer’s transformative impact on both product quantity and quality.&nbsp;<h5>3. Versatile Automation Across Bioprocesses:&nbsp;</h5>All three bioreactor runs—each employing distinct control logics (Table 2)—were successfully managed through automated feedback using the process Raman analyzer. Its flexible design, including easily swappable probes, supports seamless adaptation to other critical metabolites such as amino acids, making it a universal solution for bioprocess control.&nbsp;<h5>4. Foundation for Intelligent Manufacturing:&nbsp;</h5>With its real-time, data-rich insights and seamless integration into automated systems, the MarqMetrix All-InOne analyzer is not just a monitoring tool; it is a cornerstone technology for intelligent, AI-driven biomanufacturing. It enables consistent, high-quality production while reducing time, cost, and variability.

News from LabRulezICPMS Library - Week 27, 2026

Scientists from CEITEC Brno University of Technology led by Markéta Kaiser have achieved a globally unique breakthrough in coral research. Using the live microCT method, they were able, for the first time ever, to observe the growth of living marine corals in real time and reveal the processes behind the formation of their calcium carbonate skeletons, which had previously remained hidden beneath the surface. The results of the international study, published in the prestigious journal Science Advances, show how corals grow, regenerate, and respond to stress and competing organisms.The <a target="_blank" rel="noopener noreferrer" href="https://www.science.org/doi/10.1126/sciadv.aee3183">study</a> was carried out through a collaboration between researchers from Brno, Vienna, and several other international institutions. A key role was played by the X-ray Micro and Nano Computed Tomography Laboratory (CTLAB) at CEITEC BUT, where all the crucial data and three-dimensional coral models were produced. CEITEC also shares both the first and corresponding authorship of the study.“Thanks to live microCT, we were able, for the first time, to observe what happens beneath the surface of a coral skeleton,” explains Markéta Kaiser from CTLAB at CEITEC BUT. “For example, we witnessed situations where a coral, after being attacked by algae, completely halted its normal growth and began building a protective wall around the threatened area. Once the danger had passed, it was able to resume its original growth pattern.”<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_540e183e84.jpeg" alt="CEITEC BUT/Jakub Rozboud: Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life: Markéta Kaiser, CTLAB CEITEC at CEITEC BUT." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_540e183e84.jpeg 235w," sizes="100vw" width="1600" height="1067">The scientists successfully captured coral growth both vertically and horizontally, the formation of protective barriers against competing organisms, and regeneration mechanisms following damage.The research was exceptionally demanding from a technological standpoint. The team had to develop a special system that enabled living corals to be safely scanned directly in seawater. The coral colonies regularly traveled by train from Vienna to Brno for measurements and, after several hours, were transported back to professional aquarium systems in Vienna.“At first, it seemed like a somewhat crazy idea. No one knew whether living corals could withstand repeated scanning,” says Kaiser. “Gradually, however, we found that they survived, continued to grow, and provided us with unique data.”<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_2_fcbb29a4f6.jpeg" alt="CEITEC BUT/Jakub Rozboud: Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life: Markéta Kaiser is placing a coral sample into CT for scanning." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_2_fcbb29a4f6.jpeg 235w," sizes="100vw" width="1600" height="1067">The original concept for the project came from developmental biologist Igor Adameyko of the Medical University of Vienna, who proposed combining marine biology with advanced imaging technologies more commonly used in engineering and technical fields.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_3_8c5f376f41.jpeg" alt="CEITEC BUT/Markéta Kaiser: Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life: Corals CT - 1." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_3_8c5f376f41.jpeg 228w," sizes="100vw" width="1600" height="1096">The findings of the Brno researchers have already attracted the attention of experts in Okinawa, Japan, who specialize in coral reef research. They plan to use the live microCT method to study the effects of light, photosynthesis, and environmental changes on coral growth.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_4_445c1cc3b7.jpeg" alt="CEITEC BUT/Markéta Kaiser: Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life:Corals CT - 2." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_4_445c1cc3b7.jpeg 245w," sizes="100vw" width="1600" height="988">According to the researchers, the project demonstrates the importance of interdisciplinary collaboration between engineering and biological sciences. The research could contribute not only to the study and conservation of coral reefs, but also to fields such as paleontology and materials science.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_5_514ee9c974.jpg" alt="CEITEC BUT/Markéta Kaiser: Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life: Corals CT - 3." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_5_514ee9c974.jpg 143w," sizes="100vw" width="1600" height="1750"><blockquote><h4>Original Article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://www.science.org/doi/10.1126/sciadv.aee3183">Coral growth, retraction, defense, and regenerative strategies revealed by live microCT</a></h4>Karina Araslanova, Marketa Kaiser, Anton Fetisov, Diana Gavrik, Tomas Zikmund, Daniel Abed-Navandi, Karel Katovský, Jozef Kaiser, Igor AdameykoSci. Adv., 2026, 12, eaee3183<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1126/sciadv.aee3183">https://doi.org/10.1126/sciadv.aee3183</a><h6>licenced under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote><h4>Abstract</h4>Understanding how corals build and remodel their skeletons is key to explaining reef resilience, yet most insights come from static imaging. Using longitudinal live microCT, we tracked the same coral colonies over weeks to months at micrometer resolution. Coral skeleton formation is not a uniform accretion process but a dynamic integration of multiple programs, including vertical and horizontal patterned growth, previously undescribed defensive wall-building against competitors, exploratory edge behavior with reversible expansions and retractions, and skeletal regeneration favoring rapid, imprecise yet effective matrix expansion. Time-resolved imaging links colony-scale growth to microscale events, showing that all modes depend on balances between fusion of skeletal microparticles and layered matrix deposition, guided by tissue prepatterning. Beyond corals, this framework generalizes to studying skeletal dynamics across diverse biomineralizing organisms.

Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life 

Article

Application

Academy

Science and research

Since its establishment in 2011, CEITEC has quickly developed into a cutting-edge infrastructure for research which performs highly alongside the best institutes in Europe. Among the main priorities of CEITEC are the promotion of a motivating and dynamic international scientific environment, the provision of state-of-the-art research infrastructure, and the policy of open communication and equal opportunities.

CEITEC

Eurachem is a European network promoting international traceability of chemical measurements and good analytical practice. It provides expert guidance, supports method validation, uncertainty evaluation, proficiency testing, and facilitates discussion on technical and policy issues in analytical quality.

Eurachem

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Metrohm

Anton Paar

Agilent Technologies

Unchained Labs

Bruker

Wiley

SciY/Mestrelab Research

Join me as I discuss various techniques and provide tips and tricks on achieving the best sensitivity and detection limits on your ICP-MS.
We will be covering tuning techniques, nebulizers, lens and other strategies that will ensure your system is performing at its best.
<blockquote>
Presenter: Bert Woods (Application Scientist, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Joined the Agilent ICP-MS team in 2004, with previous employment in the semiconductor industry with Dominion Semiconductor (IBM/Toshiba) and Micron. Bert is a 1997 Chemistry graduate of Radford University in Virginia and an avid Washington DC Sports fan.
</blockquote>

Agilent Technologies: ICP-MS Tips and Tricks For Tuning and achieving the best Sensitivity and Detection Limits

ICP-MS Tips and Tricks For Tuning and achieving the best Sensitivity and Detection Limits

Various techniques and provide tips and tricks on achieving the best sensitivity and detection limits on your ICP-MS.

ICP-MS Tips and Tricks For Tuning and the best Sensitivity

Are you involved in QC of edible oils and oil seeds in the lab or in production? Learn how to use FT-NIR spectroscopy for quantification, identification and authentication of edible oils like olive oil and more in virtual workshop with expert advice and hands-on demonstrations. Discover why FT-NIR spectroscopy is a powerful alternative to conventional technologies.
FT-NIR spectroscopy will not only analyze the general composition of the oil to know if it is fit-for-purpose for the given task and if the quality is according to the standards. It can also determine oxidation parameters to assess the shelf life of the product. Dedicated examples like the analysis of olive oils, frying fats and marine oils will be featured.
<h5>Agenda:</h5>
<ul>
<li>Dagmar Behmer of Bruker Optics will explain how FT-NIR spectroscopy works and give an overview on Bruker’s rugged FT-NIR analyzers. The portfolio ranges from small footprint, touch screen operated analyzers to fully automated in-process systems for the analysis of oilseeds and finished oils throughout the entire manufacturing process. You will learn about the available calibration packages for the various oil types and which parameters are included.
</li>
<li>A hands-on demonstration from Bruker’s application lab will show the ease of use of FT-NIR spectroscopy for the analysis of oils as well as oilseeds. This demo will give you an idea how you can implement it into your lab routine. 
</li>
<li>Sven Seifer from Maxfry will talk about how FT-NIR helped to speed up their development of additives for the frying industry and how it is used in their daily QC routines. Moreover, Maxfry developed analytical services for the assessment of olive oils based on FT-NIR to determine the age, remaining shelf-life, identity, possible debasement, quality characteristics and aroma profile of the product. A tool on which a range of private and public institutes, as well as numerous testing bodies, already rely on.
</li>
<li>Live Q&amp;A where we will answer your questions regarding the use of FT-NIR spectroscopy.
</li>
</ul>
<h5>Key Learning Points</h5>
<ul>
<li>Discover Bruker’s portfolio of analytical solutions for the edible oils and oilseeds industry.
</li>
<li>Learn how FT-NIR can be utilized for analyzing quality and authenticity of edible oils &amp; fats in the lab as well as online.
</li>
<li>See how Maxfry implemented FT-NIR spectroscopy in their daily routine analysis and for their analytical services for olive oil.
</li>
</ul>
<h5>Who Should Attend?</h5>
The webinar will appeal to anybody involved in quality control of edible oils &amp; fats, but also oilseeds in the laboratory or production floor. It will also be relevant to people working in the food industry using oils and fats in their production process.
<blockquote>
Presenter: Sven Seifer (Maxfry GmbH, Technical Sales Manager)
</blockquote>
<blockquote>
Sven Seifer works for Maxfry GmbH since its foundation in 2002. After receiving a vocational training in a B2B communication agency, he is today leading the marketing communication as well as the technical sales at Maxfry.
</blockquote>
<blockquote>
With his broad knowledge of edible oils and FT-NIR spectroscopy, he is well versed in advising customers about technical aspects of oils as well as how NIR can be utilized to obtain as much information as possible about the various types of oil.
</blockquote>
<blockquote>
Presenter: Dagmar Behmer (Bruker Optics, Marketing Manager Applied Spectroscopy)
</blockquote>
<blockquote>
Dagmar Behmer holds an MSc degree in Analytical Chemistry and is today Marketing Manager of the Applied Spectroscopy business area of Bruker.
</blockquote>
<blockquote>
She is looking back on more than 25 years of experience with FT-NIR spectroscopy, focusing on food and agricultural applications and edible oils &amp; fats in particular.
</blockquote>
<blockquote>
Dagmar published several papers on olive oil and frying fats as well as book chapters on non-destructive analysis of food with FT-NIR spectroscopy. She is member of AOCS American Oil Chemists&#39; Society) and the DGF (Deutsche Gesellschaft für Fettwissenschaft).
</blockquote>

Bruker: Oils, Seeds and more: Quality Control with FT-NIR along the Production Chain

Oils, Seeds and more: Quality Control with FT-NIR along the Production Chain

Learn how FT-NIR Spectroscopy can upgrade your QC.

Oils, Seeds and more: Quality Control with FT-NIR

Join us for a webinar on “CASE (Computer-Assisted Structure Elucidation) Studies for Benchtop NMR system” presented by Dr. Ronald Soong, Senior Research Associate at the Environmental NMR Center, University of Toronto Scarborough.
Explore the increasing popularity of benchtop NMR systems in undergraduate laboratories and gain insights into the selection of the most suitable system for educational objectives. Discover how artificial intelligence software, specifically Mnova Structure Elucidation, is employed to assess the impact of magnetic field strength on structure elucidation accuracy, comparing results with a high-field NMR spectrometer for comprehensive analysis of benchtop systems in undergraduate-level structure determination.
<h4>Abstract</h4>
The increasing popularity of benchtop (BT) NMR systems has led to their widespread adoption in undergraduate laboratories globally. These systems, characterized by their affordability due to the absence of a superconducting magnetic core and user-friendly operation, align well with the learning goals set in undergraduate organic chemistry curricula. Given the range of available BT NMR systems (e.g., 43, 60, 80, and 100 MHz), instructors may find it challenging to select the most suitable system for their educational objectives. When employed as tools for structure elucidation, the primary focus often revolves around solving chemical structures, prompting questions about the magnetic field strength requirements for de novo structure elucidation for BT NMR system. To address this inquiry, we utilized an artificial intelligence (AI) software packages: Mnova Structure Elucidation (v 14.2.3) from Mestrelab Research. This software package offer impartial and distinct metrics to assess the impact of magnetic field strength on the accuracy of determined structure. To facilitate comparison, results obtained from these BT magnetic field strengths were juxtaposed with those derived from a high-field NMR (500 MHz) spectrometer. This comprehensive analysis provides insights into the advancements and limitations of the current BT systems for structure determination at a undergraduate level.
<blockquote>
Presenter: Dr. Ronald Soong (Senior Research Associate – Environmental NMR Center, University of Toronto Scarborough)
Dr. Ronald Soong graduated from the University of Toronto with a Ph.D. in Physical Chemistry. Later, he did 2 years of postdoctoral studies at the University of Michigan where he developed solid-state NMR pulse sequences for membrane protein structure determination under the supervision of Prof. Ramamoorthy. In 2010, he joined the Environmental NMR Centre as Senior Scientist and NMR Manager. Currently, Dr. Ronald Soong is developing NMR techniques and applications for both high field and benchtop NMR system with focus on environmental science, mixture analysis and chemical education.
</blockquote>

Mestrelab Research S.L.: CASE: (Computer-Assisted Structure Elucidation) Studies for Benchtop NMR system

CASE: (Computer-Assisted Structure Elucidation) Studies for Benchtop NMR system

Computer-Assisted Structure Elucidation for Benchtop NMR

Are you seeing a loss in sensitivity? Are your RSDs inconsistent? Are you facing instrument downtime issues due to need for frequent maintenance? These questions and many others have been observed by users and lead to hours of troubleshooting to find the cause of the problem.
Using good quality appropriate supplies for applications and proper maintenance of different components in the workflow will help to achieve good quality data and enhance productivity.
In this webinar, we will discuss:
<ul>
<li>The function of all the critical components in the sample introduction system and workflow.
</li>
<li>Using right kind of supplies for your applications.
</li>
<li>Tips &amp; tricks on maintenance &amp; troubleshooting.
</li>
</ul>
Attend all three sessions to get an e-certificate plus limited-time discount on selected supplies.
Note - Discounts are applicable for India only
<blockquote>
Presenter: Dr. Rajni Mujoo (Technical Support Specialist, Chemistries &amp; Supplies Division Agilent Technologies)
Dr. Rajni is working with us as Technical Support Specialist in Chemistries and Supplies Division at Agilent Technologies since 2011. She has a Ph.D degree in Food Science from CFTRI, Mysore and Post Doctorate from Department Of Food Science, Michigan State University. She also has four International Presentations &amp; 13 publications in reputed National &amp; International journals to her credit. Rajni has a total work experience of 16 yrs spread across research and Sales building expertise in different Instrument techniques.
</blockquote>

Agilent India - Excellence Lab Webinar Series-LC, GC and Spectroscopy Supplies

Boost Productivity of your Elemental Analysis with Spectroscopy Supplies

Components in the sample introduction system and workflow, using right supplies for your applications and tips & tricks on maintenance & troubleshooting.

Boost your Elemental Analysis with Spectroscopy Supplies

When it comes to chemical quantitative analysis, researchers often find themselves navigating multiple software packages. Mastering these tools to achieve the same level of expertise and reproducibility is a major pain point.
Further disruption to the workflow can occur when one needs to switch tools depending on the analytical technique or data format or even resort to using spreadsheets or in-house tools that require manual processes and are prone to error. 
To overcome these challenges, Wiley’s new KnowItAll Quantitation tool provides a single, easy-to-use tool to perform these tasks consistently in a vendor-neutral environment. 
<h4>In this session we will:</h4>
<ul>
<li>Introduce KnowItAll’s simple and intuitive quantitation process, its unique features, and how it can streamline and enhance your analytical workflow.
</li>
<li>Demonstrate through live examples the various methods supported by KnowItAll: external calibration, internal calibration, and standard addition analysis, and how to successfully quantify spectra of unknown concentration.
</li>
</ul>
<h4>This session is recommended for:</h4>
<ul>
<li>Scientists and analytical chemists who use AT-IR, IR, GC-MS, Raman, and UV-Vis techniques for spectral quantitative analyses.
</li>
<li>Professors and students engaged in analytical chemistry and quantitative analysis courses or lab work.
</li>
</ul>
<h4>About KnowItAll Solutions:</h4>
KnowItAll offers solutions to analyze and manage multiple types of spectral and chemical data in multiple file and instrument formats. KnowItAll&#39;s integrated toolsets eliminate the need for multiple software packages and increase overall lab efficiency. Combined with the comprehensive spectral reference database, KnowItAll provides chemists the most advanced technology available for spectral analysis.
<blockquote>
Presenter: Dr. Leanna Ergin (Assistant Editor, Wiley Science Solutions)
</blockquote>
<blockquote>
 Q&amp;A with:
Nadia Laschuk (Product Manager - Software and Databases - New Techniques)
Michelle D’Souza (Product Manager, Software Products)
</blockquote>

Wiley: Introducing KnowItAll Quantitation: Complete & Simplify Your Analytical Workflow

Introducing KnowItAll Quantitation: Complete & Simplify Your Analytical Workflow

We will Introduce KnowItAll’s simple and intuitive quantitation process and demonstrate through live examples the various methods supported by KnowItAll.

Introducing KnowItAll Quantitation

Get ready to dive into the thrilling world of process analytics - game show style!
Join us for an engaging and educational event as you showcase your knowledge by answering questions to discover how process analyzers can be equipped with titration, ion chromatography or spectroscopy to solve even the toughest challenges.
Our hosts, Elena Hagemann, Product Manager for Process Spectroscopy, and Kraig Kmiotek, Product Manager for Process Wet Chemistry, will test your knowledge while introducing the FUNdamentals of process analytics and unraveling practical insights that can be applied in real-world situations.
Whether you&#39;re a seasoned expert or just curious about the basics, this interactive event promises to educate and entertain, combining the fun of a game show with the science and engineering of process analytics.
Register now, don’t miss out on the end-of-the-year fun!
<blockquote>
Presenter: Kraig Kmiotek (Product Manager for Process Wet Chemistry, Metrohm USA)
</blockquote>
<blockquote>
Kraig Kmiotek is the Product Manager for Process Wet Chemistry at Metrohm USA and has a Bachelor of Science in Chemistry from Purdue University. Since joining the Process Analytics team, his focus has been on application work, analyzer design and programming and customer and internal training of process analyzers. He is currently responsible for understanding customer requirements, driving product and service development, and strategic product marketing and demand generation.
</blockquote>
<blockquote>
Presenter: Elena Hagemann (Product Manager for Process Spectroscopy, Metrohm USA)
</blockquote>
<blockquote>
Elena Hagemann is the Product Manager for Process Spectroscopy at Metrohm USA in Riverview, Florida. She holds a master’s degree in Analytical and Bioanalytical Chemistry from the Applied University of Aalen, Germany, where her master thesis focused on Karl Fischer Titration, NIR Spectroscopy, and Multivariate Data Analysis. Elena joined the Metrohm Group in August 2013 and started with Metrohm USA in January 2018, focusing on Raman and NIR Spectroscopy.
</blockquote>

Metrohm: Process Analytics Showdown: Putting the Fun in Fundamentals

Process Analytics Showdown: Putting the Fun in Fundamentals

Anton Paar is proud and excited to introduce the brand-new, next-generation Multiwave 7101/7301/7501 series of microwave digestion systems! Featuring three distinct models to suit your specific needs, the new Multiwave series surpasses the promises of next-generation microwave digestion and provides a solution for anyone who needs to prepare any sample for ICP-MS or OES analysis.
We invite you to meet the new Multiwave series during a live webinar discussing microwave digestion theory, application examples, and how the Multiwave 7101, 7301, and 7501 systems meet your lab’s needs.
Specific topics include:
<ul>
<li>Sample preparation - the key to high-quality analytical data</li>
<li>Using microwave reactors for fast, high-throughput acid digestion</li>
<li>Pressurized digestion cavity systems and their benefits</li>
<li>Introducing the new Multiwave series models</li>
<li>Key microwave digestion applications</li>
</ul>
There will also be a live Q&amp;A session following the presentation. Come meet a better microwave digestion system – the one made just for you.
<blockquote>
Presenter: Dr. Astrid-Caroline Knall
</blockquote>

Anto Paar: Demanding Samples, Easy Digestions. Meet the Multiwave 7101/7301/7501 series

Demanding Samples, Easy Digestions. Meet the Multiwave 7101/7301/7501 series

We will  discussing microwave digestion theory, application examples, and how the Multiwave 7101, 7301, and 7501 systems meet your lab’s needs.

Easy Digestions: Meet the Multiwave 7101/7301/7501 series

<blockquote>
Presenter: Louis Tisinger, PhD (Application Engineer, Molecular Spectroscopy, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Louis (Lou) Tisinger has a Ph.D. in Analytical Chemistry from Miami University in Oxford Ohio, where his graduate research involved the study of ATR imaging and microscope performance in vibrational spectroscopy. Most of his career has been related to pre- and post-sales support of FTIR spectrometers, microscopes, imaging systems, and thermal analytical instruments, focusing on analyzing customer samples, demonstrations, post-sales training, troubleshooting, and R&amp;D.
</blockquote>

IR Analysis of Microplastics

A method driven system for analysis of microplastics will be demonstrated.

In this webinar, we will discuss several solid-state NMR experiments in material research, from 1D to multidimensional homonuclear and heteronuclear correlation experiments.
<blockquote>
Presenter: ochem Struppe, PhD (Sr Applications Scientist II, Bruker BioSpin)
</blockquote>
<blockquote>
Jochem Struppe received his Dr. rer. nat. in Physics from University of Stuttgart, Germany in 1996. Following a post-doctoral position at the University of California San Diego, he joined Bruker 1999 as the Applications Engineer in California. September 2000, he joined the applications group in Billerica. Leading the solid-state NMR team in Billerica he enjoys developing new experiments and exploring CPMAS probe hardware limits nondestructively and destructively.
</blockquote>
<blockquote>
Presenter: Shane Pawsey, PhD (Senior Application Scientist I, Bruker BioSpin)
</blockquote>
<blockquote>
Shane Pawsey obtained his Ph.D. in Chemistry at McGill University and was focused on the study of structure and dynamics of self-assembled monolayers by solid state NMR. This was followed by a fellowship at the National Research Council of Canada where he developed instrumentation for hyperpolarized xenon NMR to study functionalized porous materials. Shane joined Bruker BioSpin in 2008 as an applications scientist specializing in solid state NMR. In 2010 he returned to the field of hyperpolarization and joined with the Dynamic Nuclear Polarization group in Billerica to grow new applications.
</blockquote>

Bruker: Solid State NMR Applications for Materials

Solid State NMR Applications for Materials

<h5>The Problem</h5>Cracking the code to your perfect LNP formulation is no easy feat. With tons of options like ionizable lipid design, structural lipids, and molar ratios; not to mention process parameters, which add even more complexity, nailing your LNP formulations with one-by-one methods takes up too much time, sample, and resources.&nbsp;<h5>The Solution</h5>Sunscreen is the only automated, high-throughput screening platform that helps you hit lightspeed when screening LNPs by creating 96 unique, small volume formulations in less than 6 hours- so you can explore formulations to your utmost wishes. Sunscreen’s all about microfluidic precision, no unscalable, unpredictable pipette mixing in sight – just highly controlled sizes with stellar distributions, and a direct pathway for scale-up.<h5>The Proof</h5>In this seminar, you’ll see what makes Sunscreen the primo LNP formulation screener. We’ll show you how easy prep and screening 96 formulations on Sunscreen can be, as well as how Sunscreen seamlessly integrates into a broader workflow. Plus, we’ll dish out real-world results on how Sunscreen has helped customers accelerate their workflows.<blockquote>Presenter: Ben Knappett (Product Manager - Sunny Suite, Unchained Labs)Presenter:&nbsp;Alex Kerr (Senior Applications Scientist, Unchained Labs)</blockquote>

Unchained Labs: Lightspeed LNP Formulation Screening with Sunscreen

Lightspeed LNP Formulation Screening with Sunscreen

In this seminar, you’ll see what makes Sunscreen the primo LNP formulation screener.