<p><strong>In the next 14 days, the following webinars await you in the field of spectroscopy</strong></p>
<blockquote>
<h4><a href="https://icpms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4>
</blockquote>
<h5><strong>1. Agilent Technologies: Characterization of Microplastics in Sediment Using Stereomicroscopy and Laser Direct Infrared (LDIR) Spectroscopy</strong></h5>
<ul>
<li>Mo, 9.1.2023, 21:30 (CET)</li>
</ul>
<p>In this work, we analyzed MPs in sediment using laser direct infrared (LDIR) imaging, a relatively new technique in environmental MP studies.</p>
<h5><strong>2. Agilent Technologies: New Year resolution for my ICP-MS: I will keep my ICP-MS analysis free from contaminants</strong></h5>
<ul>
<li>Tu, 10.1.2023, 21:30 (CET)</li>
</ul>
<p>In this webinar, we will discuss ways to prevent cross contamination and carryover, as well as tips and trick on analyzing.</p>
<h5><strong>3. Agilent Technologies: Common UV-Vis Questions Answered</strong></h5>
<ul>
<li>Th, 12.1.2023, 20:00 (CET)</li>
</ul>
<p>Join us in this webinar where we will discuss some of the most common questions for UV-VIS data collection.</p>
<h5><strong>4. Agilent Technologies: Picking the Right UV-Vis-NIR For Me: What Specs Do I Need?</strong></h5>
<ul>
<li>Fr, 13.1.2023, 19:00 (CET)</li>
</ul>
<p>Key performance differentiators between UV-VIS-NIR spectrometers as well as the impact that these have on measurement capabilities.</p>
<h5><strong>5. Agilent Technologies: Fast assay of Tablets, Capsules, and other Dosage forms using Transmission Raman Spectroscopy and SORS Raman Spectroscopy</strong></h5>
<ul>
<li>Mo, 16.1.2023, 21:30 (CET)</li>
</ul>
<p>This online seminar provides a comprehensive introduction to the TRS and SORS technologies and their applications.</p>
<h5><strong>6. Wiley Analytical Science: Synthetic Cannabinoid Analysis &amp; Classification of IR Spectra by Bridge Carbonyl Bands</strong></h5>
<ul>
<li>Tu, 17.1.2023, 16:00 (CET)</li>
</ul>
<p>A new patented technology that examines the distinct bridge carbonyl band patterns and forensic databases in this type of analysis.</p>
<h5><strong>7. Agilent Technologies: New Year resolution for my ICP-OES: I will keep my ICP-OES analysis free from contaminants</strong></h5>
<ul>
<li>Tu, 17.1.2023, 21:30 (CET)</li>
</ul>
<p>We will discuss ways to prevent cross contamination and carryover, as well as tips and trick on analyzing samples with heavy/dirty matrices with ICP-OES.</p>
<h5><strong>8. Agilent Technologies: Software BootCamp Kick-off - MP-AES</strong></h5>
<ul>
<li>Th, 19.1.2023, 20:00 (CET)</li>
</ul>
<p>Agilent MP Expert software is supplied with all MP-AES instruments and is your gateway to complete control of your analysis.</p>
<h5><strong>9. Agilent Technologies: Rapid, automated characterization of microplastics using laser direct infrared imaging and spectroscopy</strong></h5>
<ul>
<li>Fr, 20.1.2023, 10:00 (CET)</li>
</ul>
<p>Recent advances in infrared micro-spectroscopy combining a Quantum Cascade Laser (QCL) with scanning optics has created a new paradigm, (LDIR).</p>
<h5><strong>10. Agilent Technologies: Laser ablation – a mature technique for analysis of solid samples</strong></h5>
<ul>
<li>Fr, 20.1.2023, 19:00 (CET)</li>
</ul>
<p>In this webinar we will set the stage for an open Q&amp;A by introducing the benefits of laser ablation for many types of elemental analysis.</p>


Webinars LabRulezICPMS Week 2-3/2023

<p><strong>In the next 14 days, the following webinars await you in the field of atomic and molecular spectroscopy and spectrometry</strong></p>
<blockquote>
<h4><a href="https://icpms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4>
</blockquote>
<h5><strong>1. Agilent Technologies: Measurement of Content Uniformity Using the TRS100 Quantitative Pharmaceutical Analysis System</strong></h5>
<ul>
<li>Mo, 30.1.2023, 21:30 (CET)</li>
</ul>
<p>The Agilent TRS100 Raman system is ideal for fast assay of tablets, capsules, and other dosage forms.</p>
<h5><strong>2. Metrohm: Fluorescence-Free Raman at 785nm</strong></h5>
<ul>
<li>Tu, 31.1.2023, 19:00 (CET)</li>
</ul>
<p>We will explain how XTR works and show different use cases for both qualitative and quantitative measurements, including biodiesel and polyurethane production.</p>
<h5><strong>3. Agilent Technologies: Got ICP-OES questions? We got answers!</strong></h5>
<ul>
<li>Tu, 31.1.2023, 21:30 (CET)</li>
</ul>
<p>We will address the most asked questions from customers, as well as important questions to ask when evaluating an ICP-OES.</p>
<h5><strong>4. Agilent Technologies: A Discussion on Sample Preparation of Water Samples for Analysis of Microplastics</strong></h5>
<ul>
<li>Th, 2.2.2023, 20:00 (CET)</li>
</ul>
<p>Please join us for the next presentation in this series which will highlight Agilent’s turn-key approach for analyzing microplastics using the 8700 LDIR.</p>
<h5><strong>5. Agilent Technologies: Demystifying Digestions: an Hour to Better Sample Prep</strong></h5>
<ul>
<li>Fr, 3.2.2023, 19:00 (CET)</li>
</ul>
<p>In this webinar you will learn how microwaves digest samples, recommendations on sample size and acid combinations, what good vs. bad digests look like, and where to go for help when you need it.</p>
<h5><strong>6. Agilent Technologies: Creating Helpful Incentives to Produce Semiconductors (CHIPS) Act – Is my laboratory ready to run semiconductor applications?</strong></h5>
<ul>
<li>Tu, 7.2.2023, 21:30 (CET)</li>
</ul>
<p>In this webinar we will discuss the possible impact of the CHIPS ACT in a state near you and outline the steps necessary to ready your lab to supply and support these emerging needs. </p>
<h5><strong>7. C&amp;EN/Photothermal Spectroscopy: Sub-500nm Simultaneous IR+Raman Microscopy for Microplastics and Materials Science Research</strong></h5>
<ul>
<li>We, 8.2.2023, 17:00 (CET)</li>
</ul>
<p>This webinar discusses this novel technique and provides numerous application examples.</p>
<h5><strong>8. Agilent Technologies: The latest MH software for ICPMS improvements and upgrades</strong></h5>
<ul>
<li>Th, 9.2.2023, 20:00 (CET)</li>
</ul>
<p>In this webinar, we will discuss the improvements and additional features in Mass Hunter software MH 5.2 to keep your analysis running smoothly.</p>


Webinars LabRulezICPMS Week 5-6/2023

<p><strong>In the next 14 days, the following webinars await you in the field of atomic and molecular spectroscopy and spectrometry</strong></p>
<blockquote>
<h4><a href="https://icpms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4>
</blockquote>
<h5><strong>1. Agilent Technologies: Creating Helpful Incentives to Produce Semiconductors (CHIPS) Act – Is my laboratory ready to run semiconductor applications?</strong></h5>
<ul>
<li>Tu, 7.2.2023, 21:30 (CET)</li>
</ul>
<p>In this webinar we will discuss the possible impact of the CHIPS ACT in a state near you and outline the steps necessary to ready your lab to supply and support these emerging needs. </p>
<h5><strong>2. C&amp;EN/Photothermal Spectroscopy: Sub-500nm Simultaneous IR+Raman Microscopy for Microplastics and Materials Science Research</strong></h5>
<ul>
<li>We, 8.2.2023, 17:00 (CET)</li>
</ul>
<p>This webinar discusses this novel technique and provides numerous application examples.</p>
<h5><strong>3. Agilent Technologies: The latest MH software for ICPMS improvements and upgrades</strong></h5>
<ul>
<li>Th, 9.2.2023, 20:00 (CET)</li>
</ul>
<p>In this webinar, we will discuss the improvements and additional features in Mass Hunter software MH 5.2 to keep your analysis running smoothly.</p>
<h5><strong>4. Shimadzu Corporation: Introducing the latest version Lab-at-a-glance powered by LabSolutions BiX</strong></h5>
<ul>
<li>Tu, 14.2.2023, 07:00 (CET)</li>
</ul>
<p>LabSolutions BiX enables the monitoring of the Live Status of laboratory activities, the efficiency of laboratory users, instrument utilization, and other new features...</p>
<h5><strong>5. Separation Science/Agilent Technologies: Computerized System Validation: GAMP 5 2nd Edition, What You Need to Know</strong></h5>
<ul>
<li>We, 15.2.2023, 16:00 (CET)</li>
</ul>
<p>We shall take a look at the contents of the long awaited GAMP 5 Version 2 release to examine what has truly changed since the Version 1 release, with special focus on Pharma, BioPharma, and Biotech industries.</p>
<h5><strong>6. Agilent Technologies: Infrared Analysis of Microplastics as Prescribed by the Southern California Coastal Water Research Project (SCCWRP) SOP, Using the Agilent 8700 LDIR</strong></h5>
<ul>
<li>Th, 16.2.2023, 20:00 (CET)</li>
</ul>
<p>This presentation will discuss how the LDIR can be used to automate the analysis of microplastics, following the analytical steps prescribed by the SOP. </p>


Webinars LabRulezICPMS Week 6-7/2023

<p><strong>After many heartfelt speeches the organizing team was rewarded with small gifts.</strong></p>
<p><strong>The ESAS organizing team would like to thank all the participants of the conference and look forward to the next conference, where we will all meet again in good health and good spirits.</strong></p>
<blockquote>
<p>💡💡💡 <a href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/ESAS_2022_BOOK_OF_ABSTRACTS_a222376ad0/ESAS-2022-BOOK-OF-ABSTRACTS.pdf"><strong>BOOK OF ABSTRACTS ESAS-CSSC 2022</strong></a></p>
</blockquote>
<h3><strong>Programme friday 9th of September 2022</strong></h3>
<h4><strong>LASER INDUCED BREAKDOWN SPECTROMETRY</strong></h4>
<ul>
<li>(Hall P31) CHAIR: GALBÁCS</li>
</ul>
<h5><strong>9:00 – 9:30 Complementarity of laser-induced breakdown spectroscopy and laser ablation inductively coupled plasma mass spectrometry in cancer tissues analysis</strong></h5>
<ul>
<li>IL 28: P. POŘÍZKA</li>
</ul>
<p>It has been shown that cancerous tissues change the chemical composition of cells <strong>Error! Reference source not found.</strong> These changes in elemental composition can be observed using Laser-Induced Breakdown Spectroscopy (LIBS) or Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS), where imaging of biotic (e.g., C, P, Ca, Mg) and trace (e.g., Zn, Cu) elements provides information about the distribution of soft tissue elements and, consequently, the location of cancerous tissue.</p>
<p>This paper deals with a correlative study using LIBS and LA-ICP-MS in a sample of healthy human skin, four samples of malignant tumours (squamous cell carcinoma, malignant melanoma, basal cell carcinoma, and epithelioid angiosarcoma), and one sample of a benign tumour (pigmented nevus). Analysis was performed using both techniques for all these samples, and spatial distributions of selected elements were constructed. This work aims to show the potential of correlation of data obtained from both analytical methods, which could be used for the possible diagnosis of cancer as a complementary technique to classical histological examination.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SSJMM_Complementarity_of_laser_induced_breakdown_spectroscopy_and_laser_ablation_inductively_coupled_plasma_mass_spectrometry_in_cancer_tissues_analysis_P_PORIZKA_c2d66f4b01/SSJMM-Complementarity-of-laser-induced-breakdown-spectroscopy-and-laser-ablation-inductively-coupled-plasma-mass-spectrometry-in-cancer-tissues-analysis-(P.-PORIZKA).jpg" alt="SSJMM: Complementarity of laser-induced breakdown spectroscopy and laser ablation inductively coupled plasma mass spectrometry in cancer tissues analysis (P. POŘÍZKA)"/></p>
<h5><strong>9:30 – 10:00 Understanding the correlation of LIBS and acoustic measurements of rock and soil found in the traverse of Perseverance rover across the Jezero crater, Mars</strong></h5>
<ul>
<li>IL 29: J. LASERNA</li>
</ul>
<p>The SuperCam instrument of the NASA MARS 2020 Perseverance rover combines a suite of atomic and molecular spectroscopies intended for an extensive description of rocks, soils and minerals in the surroundings of the landing site of the mission – the Jezero crater. The microphone installed on the SuperCam instrument allows the acquisition of acoustic signals resulting from the expansion of laser-induced plasmas towards the atmosphere. Apart from being affected by the propagation characteristics of the Mars atmosphere, the acoustic signal has an additional component related to the properties of the target including surface morphology, hardness, deformation parameters, and elasticity, among others. This information is currently being investigated as a complementary resource for characterization of the ablated material and may well supplement the LIBS data gathered from coincident laser shots. This talk will present SuperCam acoustic data of rocks and minerals found in the traverse of the Perseverance rover and will discuss its correlation with LIBS spectra.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SSJMM_Understanding_the_correlation_of_LIBS_and_acoustic_measurements_of_rock_and_soil_found_in_the_traverse_of_Perseverance_rover_across_the_Jezero_crater_Mars_J_LASERNA_601a7a5b62/SSJMM-Understanding-the-correlation-of-LIBS-and-acoustic-measurements-of-rock-and-soil-found-in-the-traverse-of-Perseverance-rover-across-the-Jezero-crater-Mars-(J.-LASERNA).jpg" alt="SSJMM: Understanding the correlation of LIBS and acoustic measurements of rock and soil found in the traverse of Perseverance rover across the Jezero crater, Mars (J. LASERNA)"/></p>
<h5><strong>10:00 – 10:20 Laser induced breakdown spectroscopy imaging of uranium ores</strong></h5>
<ul>
<li>OL 61: K. NOVOTNÝ</li>
</ul>
<p>Laser-induced breakdown spectroscopy (LIBS) was applied to create images revealing the distribution and possible migration of elements in samples of uranium ore. Compared to SEM or LA-ICP-MS, fast LIBS scanning made it possible to perform analysis across the big sample area containing different mineral phases of uranium ores including associated minerals. However, the imaging of some associated elements is due to rich spectra and low contents still challenging. Moreover, compromise conditions have to be often set to reach the required spatial resolution, speed of scanning and sensitivity. Generally, higher resolution is paid for by the loss of sensitivity and vice versa. Nevertheless, there are some possibilities for improvement in both instrumentation and spectral data processing. Different effects such as the role of the introduction of noble gas, influence of laser wavelength or double pulse methods will be discussed.</p>
<p>The investigated geological samples represent U-mineralisation from a former deep uranium mine. Obtained elemental images help to reveal and distinguish different phases such as massive uraninite and carbonate vein or metasomatite. Additionally, the signal correlation of some elements (correlation between different emission lines) helps with the identification of other associated minerals.</p>
<h5><strong>10:20 – 10:40 LIBS applications of online monitoring and 2D/3D mappings for advanced control of industrial processes</strong></h5>
<ul>
<li>OL 62: Y. DEGUCHI</li>
</ul>
<p>Advanced monitoring and control methods are significant in the industrial processes. Laserinduced breakdown spectroscopy (LIBS) is an analytical detection technique based on atomic emission spectroscopy to measure the elemental composition, which has been widely applied in various fields (1). In this study, LIBS applications of online monitoring and 2D/3D mappings were demonstrated for advanced control of industrial processes.</p>
<p>A collinear long and short DP-LIBS method (LS-DP-LIBS) was developed to improve the detection ability and measurement accuracy by the control of the plasma cooling process using the long pulse-width laser radiation (2). The plasma generated by the short pulse-width laser is stabilized and maintained at high temperature during the plasma cooling process by long pulsewidth laser radiation. C, Al, Si, S, Ti, Cr, Ni, Cu, Nb, Mo, Mn, and B concentration measurements in molten steel samples were performed using LS-DP-LIBS. It demonstrates the feasibility of multi-element concentration measurements in iron and steel making processes and this will lead to the advanced monitoring and control methods in these processes.</p>
<p>The analysis of elemental composition distribution is indispensable to ensure the quality of various materials production. In this regard, 2D/3D mapping techniques using LIBS are widely used in various fields. In many LIBS studies, lasers with ns pulse widths are used, and the spatial resolution of 2D LIBS mapping is usually several to several tens of micrometers. In this study, a spatial resolution of 1 μm was achieved by using a laser with a pulse width of 9 ps. This LIBS mapping system consists of a picosecond laser, lens, spectrometer, ICMOS camera, and XYZ stage. The LIBS system was applied to steel and Li-ion battery electrodes for 2D elemental distribution analysis. The steel sample has a structure with Zn coating around the steel at the μm level, and this LIBS mapping system was able to detect the Zn distribution around the steel at the μm level. This result was in good agreement with the SEM-EDS measurement. LIBS has the advantage of elemental composition mapping without the need for high vacuum conditions and has many advantages when applied to industrial processes. In the future, the LIBS analysis speed is improved to 1 kHz and the LIBS system is utilized for elemental composition mapping in industrial processes.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SSJMM_LIBS_applications_of_online_monitoring_and_2_D_3_D_mappings_for_advanced_control_of_industrial_processes_Y_DEGUCHI_267fd9abf7/SSJMM-LIBS-applications-of-online-monitoring-and-2D-3D-mappings-for-advanced-control-of-industrial-processes-(Y.-DEGUCHI).jpg" alt="SSJMM: LIBS applications of online monitoring and 2D-3D mappings for advanced control of industrial processes (Y. DEGUCHI)"/></p>
<h5><strong>10:40 – 11:10 COFFEE BREAK</strong></h5>
<ul>
<li>ATRIUM OF FACULTY OF SOCIAL STUDIES</li>
</ul>
<h4><strong>LASER INDUCED BREAKDOWN SPECTROMETRY</strong></h4>
<ul>
<li>(Hall P31) CHAIR: LASERNA</li>
</ul>
<h5><strong>11:10 – 11:40 Nanoparticles in plasma spectroscopy: detection and signal enhancement in gaseous, liquid and solid samples</strong></h5>
<ul>
<li>IL 30: G. GALBÁCS</li>
</ul>
<p>Nanoscience has advanced greatly in the last two decades. Due to their special optical, mechanical, magnetic and energetic properties, nanoparticles (NPs) are nowadays exploited in many industrial, scientific and medical fields. The continuous development of nanomaterials as well as their increasing presence in the environment and biological systems also necessitates the development of such analytical methods that are capable of the sensitive detection and characterization of NPs in various sample matrices. Such methods often built on the application of laser induced breakdown spectroscopy (LIBS) or single particle inductively coupled plasma mass spectrometry (spICP-MS). At the same time, plasma spectroscopy techniques – LIBS included – also can benefit from using NPs to enhance their analytical signals. Therefore the development of NPs and plasma spectroscopy are strongly intertwined fields.</p>
<p>In this contribution, some recent results of the research group of the author obtained using LIBS and spICP-MS methods will be presented. It will be demonstrated, how various characteristics (composition, concentration, structure, size distribution, porosity, aspect ratio, etc.) of inorganic NPs and nanocomposites dispersed in aqueous liquid samples can be assessed using novel spICP-MS methodologies. The LIBS detection and characterization of NPs suspended in a gas medium and occurring in plant samples will also be described. Results on LIBS signal enhancement effectuated with the application of NPs for gas, liquid and solid samples via the exploitation of plasmonic and electron field- or thermoemission mechanisms will also be presented.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SSJMM_Nanoparticles_in_plasma_spectroscopy_detection_and_signal_enhancement_in_gaseous_liquid_and_solid_samples_G_GALBACS_ee291fadbe/SSJMM-Nanoparticles-in-plasma-spectroscopy-detection-and-signal-enhancement-in-gaseous-liquid-and-solid-samples-(G.-GALBACS).jpg" alt="SSJMM: Nanoparticles in plasma spectroscopy - detection and signal enhancement in gaseous, liquid and solid samples (G. GALBÁCS)"/></p>
<h5><strong>11:40 – 12:10 Enhancing the sensitivity of laser-induced breakdown spectroscopy for the detection of nanoparticle-labeled cancerous tissues</strong></h5>
<ul>
<li>IL 31: J. KAISER</li>
</ul>
<p>Fluorescent labels, based on conjugates of antibodies with various nanoparticles, are popular because of their broad detection posibilities (plate readers, microscopes). However, fluorescence is a limiting factor in e.g. multiplexing; only a limited number of dyes can be detected due to the overlaps of dye spectra or optical filters. Thus, novel readout methods are necessary to overcome such limitations. Laser spectroscopy – namely Laser-Induced Breakdown Spectroscopy (LIBS) – is a prospective option in nanoparticle detection (1). LIBS provides superior performance in terms of throughput and repetition rate enabling large-scale elemental imaging in combination with high lateral resolution. In this talk, we will demonstrate the feasibility of LIBS as a readout method in immunochemical assays and imaging of cancer tissues (breast cancer) through the indirect detection of upconversion nanoparticles (UCNPs) (2). The LIBS scanning enabled detecting the characteristic elemental signature of yttrium as a principal constituent of UCNP, thus indirectly providing a reliable way to differentiate between HER2-positive BT-474 cells and HER2-negative MDA-MB-231 cells. The comparison of results with upconversion optical microscopy and luminescence intensity scanning confirmed that LIBS is a promising alternative for the readout of immunohistochemical samples. Moreover, we have deployed the collinear double-pulse arrangement for enhanced sensitivity and detection capability, Fig. 1.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SSJMM_Fig_1_Signal_of_Y_II_437_49_nm_spectral_line_enhanced_by_collinear_DP_arrangement_797a0de7ba/SSJMM-Fig.-1.-Signal-of-Y-II-437.49-nm-spectral-line-enhanced-by-collinear-DP-arrangement.jpg" alt="SSJMM: Fig. 1. Signal of Y II 437.49 nm spectral line enhanced by collinear DP arrangement"/></p>
<h5><strong>12:10 – 12:30 Polychromator ORCA ( Optimized Rowland Circle Alignment )</strong></h5>
<ul>
<li>OL 63: P. KOLEČKÁŘ</li>
</ul>
<p>The lecture will discuss a spectrometer that is competitive in ICP spectrometers to ECHELLE type spectrometers. The ECHELLE optical system is very often used in ICP spectrometers, which has its advantages (in particular, it is small in size), but also a number of disadvantages, especially the very variable spectral resolution.</p>
<p>The company SPECTRO A.I. Kleve, Germany uses Paschen-Runge type spectrometers in their manufactured instruments. This lecture discusses these spectrometers. Paschen-Runge spectrometers use the Rowland circle system. They are generally larger in size than ECHELLE spectrometers, but they have a number of advantages, among which the main ones include constant and uniform spectral resolution and smaller (weaker) scattered light than<br/>in ECHELLE spectrometers.</p>
<p>The Optimized Roland Circle Alignment Concept (ORCA), as SPECTRO AI calls its patented spectrometer system, is based on the Paschen-Runge spectrometer system.</p>
<p>In this system, the spectral resolution is determined only by the diameter of the Rowland circle and the dispersion of the grating used (number of scratches/1mm). The larger the diameter of the Rowland circle and the number of scratches of the dispersion grating, the better the spectral resolution. But this cannot be increased to infinity because the light intensity decreases with the square of the distance. At twice the distance, there is a fourfold decrease in light. Therefore, a reasonable compromise must be chosen.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SSJMM_Polychromator_ORCA_Optimized_Rowland_Circle_Alignment_P_KOLECKAR_9733685e45/SSJMM-Polychromator-ORCA-(-Optimized-Rowland-Circle-Alignment-)-(P.-KOLECKAR).jpg" alt="SSJMM: Polychromator ORCA ( Optimized Rowland Circle Alignment ) (P. KOLEČKÁŘ)"/></p>
<h5><strong>12:30 – 12:50 Aerosol analysis with laser-induced breakdown spectroscopy: Sampling approaches and recent applications</strong></h5>
<ul>
<li>OL 64: D. HAHN</li>
</ul>
<p>This talk describes how laser-induced breakdown spectroscopy (LIBS) became a viable analytical tool for aerosol analysis through advances in sampling and data analysis strategies, as well as deployment applications. The analysis of aerosols is a challenging task due to the wide variation of aerosol particles characteristics (e.g., source, size, chemical composition) and measurements requirements (e.g., chemical determination, sizing, number density), however, LIBS has demonstrated to perform well analyzing both the aerosol particles and the gaseous phase, specially, in harsh conditions where other techniques are simply not applicable. By coupling the point-to-point sampling nature of laser-induced plasmas with the discrete nature of aerosols particles and selective spectra analysis (i.e., Conditional Analysis) a considerable increase in LIBS sensitivity can be achieved. Finally, an overview of aerosol LIBS applications in industrial and laboratory setting are presented to showcase the versatility and in situ applicability of LIBS with recent data, including the applications of heavy metals high temperature effluents, gas and particulate emissions from battery cells at high temperature, and<br/>vapors and aerosols from molten salts.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SSJMM_Aerosol_analysis_with_laser_induced_breakdown_spectroscopy_Sampling_approaches_and_recent_applications_D_HAHN_6361ad3f57/SSJMM-Aerosol-analysis-with-laser-induced-breakdown-spectroscopy-Sampling-approaches-and-recent-applications-(D.-HAHN).jpg" alt="SSJMM: Aerosol analysis with laser-induced breakdown spectroscopy - Sampling approaches and recent applications (D. HAHN)"/></p>
<h5><strong>12:50 – 13:10 ESAS-CSSC 2022 CLOSING CEREMONY</strong></h5>
<h5><strong>13:10 – 14:30 LUNCH</strong></h5>
<ul>
<li>MU RECTORATE</li>
</ul>


ESAS-CSSC 2022 (Day 5)

<h3><strong>HOW TO WEIGH A MOLECULE?</strong></h3>
<p>Imagine that you want <strong>to weigh a water molecule</strong>. You cannot just place it on a weighing pan because it certainly would not work. You need a much more sophisticated device called <strong>a mass spectrometer</strong>.</p>
<p><strong>The first such instrument was constructed by J. J. Thomson in 1912</strong>. Since then, mass spectrometry has developed into a fascinating field with many practical applications.</p>
<p><a href="https://lcms.labrulez.com/library?categoryItems=12&amp;instrumentationItems=31&amp;publicationTypeItems=1-7-2-5-4&amp;search=newborn+screening"><strong>Newborn screeningg</strong></a>, <a href="https://lcms.labrulez.com/library?categoryItems=3&amp;instrumentationItems=31&amp;publicationTypeItems=1-7-2-5-4&amp;search=doping"><strong>doping tests of athletes</strong></a>, <a href="https://lcms.labrulez.com/library?categoryItems=1&amp;instrumentationItems=31&amp;publicationTypeItems=1-7-2-5-4&amp;search=contaminants"><strong>analysis of pollutants</strong></a>, <a href="https://lcms.labrulez.com/library?categoryItems=5&amp;instrumentationItems=31&amp;publicationTypeItems=1-7-2-5-4&amp;search=drug"><strong>testing of new drugs</strong></a> or <strong>space exploration</strong> are only a few <strong>examples of the application of mass spectrometry</strong>. Yet there are many more.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Czech_Museum_of_MS_Mass_Spectrometer_d6267dd11d/Czech-Museum-of-MS-Mass-Spectrometer.jpg" alt="Czech Museum of MS: Mass Spectrometer"/></p>
<h3><strong>MASS SPECTROMETER</strong></h3>
<p><strong>A mass spectrometer</strong> is a remarkable instrument that <strong>provides information about the mass and structure of molecules</strong>. In essence, it is a very accurate scale for electrically charged molecules. However, such a scale does not resemble the traditional ones known from kitchens and pharmacies. It is an ingenious device that <strong>uses electric and magnetic fields to manipulate, separate and detect charged molecules</strong>. Some instruments also make it possible to break charged molecules into pieces, which is useful for deducing the molecular structure.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Czech_Museum_of_MS_A_gridless_two_stage_reflectron_from_the_MALDI_TOF_system_Biflex_II_manufactured_by_Bruker_Daltonics_690d1900fb/Czech-Museum-of-MS-A-gridless-two-stage-reflectron-from-the-MALDI-TOF-system-Biflex-II-manufactured-by-Bruker-Daltonics.jpg" alt="Czech Museum of MS: A gridless two-stage reflectron from the MALDI-TOF system Biflex II manufactured by Bruker Daltonics"/></p>
<h3><strong>OUR MISSION</strong></h3>
<p>The museum aims <strong>to collect</strong> and <strong>display artifacts in mass spectrometry</strong>, especially those <strong>associated with our geographical region</strong>. Students professionals and the general public can look a the key components of spectrometers and understand <strong>how mass spectrometers work</strong>. The technical solutions and stories behind the exhibits can inspire young scientists as wall as experienced designers of scientific instruments.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Czech_Museum_of_MS_Mass_Spectrometry_history_in_Czech_Republic_fce8ca9112/Czech-Museum-of-MS-Mass-Spectrometry-history-in-Czech-Republic.jpg" alt="Czech Museum of MS: Mass Spectrometry history in Czech Republic"/></p>
<h3><strong>EXHIBITION</strong></h3>
<p>The exhibition shows instrument components tha are often <strong>hidden in inaccessible vacuum chambers of mass spectrometers</strong>. You can take a closer look at them, understand their function, and at the same time admire their technical perfection and beauty. Use your smartphone to learn more about the exhibit you are currently viewing. <strong>The posters on the walls will teach you about mass spectrometry and its history</strong>.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Czech_Museum_of_MS_A_grid_cell_of_LTQ_FT_Ultra_Thermo_Electron_Corporation_7e8ae7d076/Czech-Museum-of-MS-A-grid-cell-of-LTQ-FT-Ultra-(Thermo-Electron-Corporation).jpg" alt="Czech Museum of MS: A grid cell of LTQ FT Ultra (Thermo Electron Corporation)"/></p>
<h3><strong>DONATE AN EXHIBIT</strong></h3>
<p>The museum accepts <strong>donations</strong> to its collection, especially <strong>instruments</strong> or <strong>parts of them</strong> (even broken, damaged or worn), <strong>documents</strong>, and <strong>photographs related to mass spectrometry and its history</strong>. All donations are highly appreciated.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Czech_Museum_of_MS_EI_source_from_the_single_quadrupole_mass_spectrometer_TRIO_1000_manufactured_by_VG_Masslab_Altrincham_UK_9824bf2fd9/Czech-Museum-of-MS-EI-source-from-the-single-quadrupole-mass-spectrometer-TRIO-1000-manufactured-by-VG-Masslab-(Altrincham-UK).jpg" alt="Czech Museum of MS: EI source from the single quadrupole mass spectrometer TRIO 1000 manufactured by VG Masslab (Altrincham, UK)"/></p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Czech_Museum_of_MS_A_triple_stage_quadrupole_LC_MS_mass_spectrometer_TSQ_Vantage_manufactured_by_Thermo_Scientific_fbf31e162f/Czech-Museum-of-MS-A-triple-stage-quadrupole-LC-MS-mass-spectrometer-TSQ-Vantage-manufactured-by-Thermo-Scientific.jpg" alt="Czech Museum of MS: A triple stage quadrupole LC-MS mass spectrometer TSQ Vantage manufactured by Thermo Scientific"/></p>
<h3><strong>FIND US HERE</strong></h3>
<h5><a href="https://www.uochb.cz/en"><strong>Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences</strong></a></h5>
<ul>
<li>Building A, 2nd floor</li>
<li>Flemingovo náměstí 542/2</li>
<li>160 00 Praha 6</li>
<li>Czech Republic</li>
</ul>
<h3><strong>HOURS AND ADMISSION</strong></h3>
<p>The museum is <strong>open daily from 8 am to 6 pm.</strong> A guide is required to move around the building.</p>
<p><strong>Please call in advance</strong> to check the guide‘s availability.</p>
<ul>
<li><strong>Inquiries:</strong> Josef Cvačka</li>
<li>+420 731 447 868</li>
<li>josef.cvacka@uochb.cas.cz</li>
</ul>
<p><strong>The admission is free for all visitors.</strong></p>
<p><strong>The Czech Academy of Sciences has contributed financially to the promotion of the museum.</strong></p>


Czech Museum of Mass Spectrometry

<p><strong>In the next 14 days, the following webinars await you in the field of atomic and molecular spectroscopy and spectrometry</strong></p>
<blockquote>
<h4><a href="https://icpms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4>
</blockquote>
<h5><strong>1. Shimadzu Corporation: Introducing the latest version Lab-at-a-glance powered by LabSolutions BiX</strong></h5>
<ul>
<li>Tu, 14.2.2023, 07:00 (CET)</li>
</ul>
<p>LabSolutions BiX enables the monitoring of the Live Status of laboratory activities, the efficiency of laboratory users, instrument utilization, and other new features...</p>
<h5><strong>2. Separation Science/Agilent Technologies: Computerized System Validation: GAMP 5 2nd Edition, What You Need to Know</strong></h5>
<ul>
<li>We, 15.2.2023, 16:00 (CET)</li>
</ul>
<p>We shall take a look at the contents of the long awaited GAMP 5 Version 2 release to examine what has truly changed since the Version 1 release, with special focus on Pharma, BioPharma, and Biotech industries.</p>
<h5><strong>3. Agilent Technologies: Infrared Analysis of Microplastics as Prescribed by the Southern California Coastal Water Research Project (SCCWRP) SOP, Using the Agilent 8700 LDIR</strong></h5>
<ul>
<li>Th, 16.2.2023, 20:00 (CET)</li>
</ul>
<p>This presentation will discuss how the LDIR can be used to automate the analysis of microplastics, following the analytical steps prescribed by the SOP. </p>
<h5><strong>4. Agilent Technologies: Advances and Strategies in ICP-OES to Handle High-Matrix Samples</strong></h5>
<ul>
<li>Th, 23.2.2023, 20:00 (CET)</li>
</ul>
<p>How the state-of-the-art ICP-OES technology can help you to improve your elemental analysis in samples containing up to 30% of total dissolved solids.</p>


Webinars LabRulezICPMS Week 7-8/2023

<p><strong>In the next 14 days, the following webinars await you in the field of atomic and molecular spectroscopy and spectrometry</strong></p>
<blockquote>
<h4><a href="https://icpms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4>
</blockquote>
<h5><strong>1. Agilent Technologies: Advances and Strategies in ICP-OES to Handle High-Matrix Samples</strong></h5>
<ul>
<li>Th, 23.2.2023, 20:00 (CET)</li>
</ul>
<p>How the state-of-the-art ICP-OES technology can help you to improve your elemental analysis in samples containing up to 30% of total dissolved solids.</p>
<h5><strong>2. Wiley Analytical Science/JMP Statistical Discovery: Making better use of Spectral and Chromatographic Data in product and process development</strong></h5>
<ul>
<li>Th, 2.3.2023, 11:00 (CET)</li>
</ul>
<p>This webinar will present a simple and efficient way of extracting the signals from the noise for a deeper, better understanding of your processes and products.</p>
<h5><strong>3. Merck: Monitoring and quality control of cell culture media preparation using Raman spectroscopy</strong></h5>
<ul>
<li>Th, 2.3.2023, 16:00 (CET)</li>
</ul>
<p>In this webinar, we will explore the possibilities of using Raman spectroscopy for quality control of cell culture media preparation.</p>
<h5><strong>4. The Analytical Scientist/ACD/Labs: How to Overcome the Challenges of Analytical Data Management</strong></h5>
<ul>
<li>Th, 2.3.2023, 16:00 (CET)</li>
</ul>
<p>The challenges related to analytical data that cross organizations and industries; and lessons learned through their own experience.</p>
<h5><strong>5. Agilent Technologies: UV-Vis Instrumentation : From Routine to Advanced Applications Part I</strong></h5>
<ul>
<li>Th, 2.3.2023, 20:00 (CET)</li>
</ul>
<p>The focus of Part I of this two part series will be on entry level and the mid-performance instrumentation and what is needed to make a variety of measurements.</p>
<h5><strong>6. Agilent Technologies: ICP-MS MassHunter How To: What are and How to use Sublists</strong></h5>
<ul>
<li>Fr, 3.3.2023, 19:00 (CET)</li>
</ul>
<p>In this ICP-MS MassHunter Software “How to…..” webinar series, we pick a most-frequent-asked topic each week and give a brief demonstration and discussion on the subject.</p>


Webinars LabRulezICPMS Week 8-9/2023

<p><strong>In the next 14 days, the following webinars await you in the field of atomic and molecular spectroscopy and spectrometry</strong></p>
<blockquote>
<h4><a href="https://icpms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4>
</blockquote>
<h5><strong>1. Agilent Technologies: Analysis of Major and Trace Constituents in Li-ion Battery Electrolyte Solutions using ICPOES</strong></h5>
<ul>
<li>Tu, 28.2.2023, 21:30 (CET)</li>
<li><a href="https://icpms.labrulez.com/webinar/2427">Registration</a></li>
</ul>
<p>We will deliver a broad overview of Li-ion battery architecture and the raw materials that go into them, a discussion of preparation of standards for neat analysis of EC/DEC/DMC.</p>
<h5><strong>2. Wiley Analytical Science/JMP Statistical Discovery: Making better use of Spectral and Chromatographic Data in product and process development</strong></h5>
<ul>
<li>Th, 2.3.2023, 11:00 (CET)</li>
<li><a href="https://icpms.labrulez.com/webinar/2388">Registration</a></li>
</ul>
<p>This webinar will present a simple and efficient way of extracting the signals from the noise for a deeper, better understanding of your processes and products.</p>
<h5><strong>3. Waters Corporation: Virtual European Workshops on Extractables &amp; Leachables for Pharma &amp; Biopharma</strong></h5>
<ul>
<li>Th, 2.3.2023, 14:00 (CET)</li>
<li><a href="https://icpms.labrulez.com/webinar/2414">Registration</a></li>
</ul>
<p>Register now for this virtual event and share knowledge and challenges with peers and E&amp;L experts.</p>
<h5><strong>4. Merck: Monitoring and quality control of cell culture media preparation using Raman spectroscopy</strong></h5>
<ul>
<li>Th, 2.3.2023, 16:00 (CET)</li>
<li><a href="https://icpms.labrulez.com/webinar/2403">Registration</a></li>
</ul>
<p>In this webinar, we will explore the possibilities of using Raman spectroscopy for quality control of cell culture media preparation.</p>
<h5><strong>5. The Analytical Scientist/ACD/Labs: How to Overcome the Challenges of Analytical Data Management</strong></h5>
<ul>
<li>Th, 2.3.2023, 16:00 (CET)</li>
<li><a href="https://icpms.labrulez.com/webinar/2390">Registration</a></li>
</ul>
<p>The challenges related to analytical data that cross organizations and industries; and lessons learned through their own experience.</p>
<h5><strong>6. Agilent Technologies: UV-Vis Instrumentation : From Routine to Advanced Applications Part I</strong></h5>
<ul>
<li>Th, 2.3.2023, 20:00 (CET)</li>
<li><a href="https://icpms.labrulez.com/webinar/2366">Registration</a></li>
</ul>
<p>The focus of Part I of this two part series will be on entry level and the mid-performance instrumentation and what is needed to make a variety of measurements.</p>
<h5><strong>7. Agilent Technologies: ICP-MS MassHunter How To: What are and How to use Sublists</strong></h5>
<ul>
<li>Fr, 3.3.2023, 19:00 (CET)</li>
<li><a href="https://icpms.labrulez.com/webinar/2410">Registration</a></li>
</ul>
<p>In this ICP-MS MassHunter Software “How to…..” webinar series, we pick a most-frequent-asked topic each week and give a brief demonstration and discussion on the subject.</p>


Webinars LabRulezICPMS Week 9/2023

<p><strong>In the next 14 days, the following webinars await you in the field of atomic and molecular spectroscopy and spectrometry</strong></p>
<blockquote>
<h4><a href="https://icpms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4>
</blockquote>
<h5><strong>1. Agilent Technologies: Elemental Analysis of Lithium-ion Battery Cathode Materials using an ICP-OES</strong></h5>
<ul>
<li>Tu, 7.3.2023, 21:30 (CET)</li>
<li><a href="https://icpms.labrulez.com/webinar/2428">Registration</a></li>
</ul>
<p>In this webinar we will discuss about how to set up an analysis for challenging matrices of lithium-ion batteries and cathode materials on ICP-OES.</p>
<h5><strong>2. Thermo Fisher Scientific: Power your elemental analysis - Get ready to transform your productivity</strong></h5>
<ul>
<li>We, 8.3.2023, 11:00 (CET)</li>
<li><a href="https://icpms.labrulez.com/webinar/2426">Registration</a></li>
</ul>
<p>This event will reveal the latest advances in ICP-MS and sample automation. </p>
<h5><strong>3. SelectScience: The basic physics of spectroscopy: Light-matter interaction for fun and profit</strong></h5>
<ul>
<li>Th, 9.3.2023, 17:00 (CET)</li>
<li><a href="https://icpms.labrulez.com/webinar/2399">Registration</a></li>
</ul>
<p>This first session of a four-part ‘Fundamentals of Spectroscopy’ course, will examine core concepts essential to understanding common optical spectroscopy methods.</p>
<h5><strong>4. Agilent Technologies: Learn How to Obtain Excellent Stability in your ICP-MS: A Conditioning Workshop</strong></h5>
<ul>
<li>Th, 9.3.2023, 20:00 (CET)</li>
<li><a href="https://icpms.labrulez.com/webinar/2367">Registration</a></li>
</ul>
<p>We will share Agilent’s default conditioning recommendations and demonstrate how to condition the cones with all the tips and tricks that Agilent Application Scientists use daily.</p>
<h5><strong>5. Agilent Technologies: 21 CFR Compliance for the Cary 3500 UV-Vis Spectrometer through Openlab Enterprise Content Management (ECM)</strong></h5>
<ul>
<li>Mo, 13.3.2023, 21:30 (CET)</li>
<li><a href="https://icpms.labrulez.com/webinar/2443">Registration</a></li>
</ul>
<p>New additions to the Cary 3500&#39;s software expand capability for data storage and method approval.</p>
<h5><strong>6. Agilent Technologies: Lithium-Ion Battery Industry Chain: Quality Control Insights from Elemental Analysis of High TDS Raw Materials and More by ICP-OES</strong></h5>
<ul>
<li>Tu, 14.3.2023, 21:30 (CET)</li>
<li><a href="https://icpms.labrulez.com/webinar/2441">Registration</a></li>
</ul>
<p>During this talk, a review of data collected from ICP-OES on various battery materials will be discussed with special emphasis on high TDS samples.</p>
<h5><strong>7. Agilent Technologies: UV-Vis Instrumentation : From Routine to Advanced Applications Part II</strong></h5>
<ul>
<li>Th, 16.3.2023, 20:00 (CET)</li>
<li><a href="https://icpms.labrulez.com/webinar/2368">Registration</a></li>
</ul>
<p>We will focus on the high end UV-Vis-nir instrumentation and the accessories which allow for a more complex measurements to be made.</p>


Webinars LabRulezICPMS Week 10-11/2023

<p><strong>An international team of scientists led by Tomáš Pluskal from the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) has introduced a new generation of software enabling scientists to analyze large volumes of data from mass spectrometry, a technique that separates chemicals by their weights. The open-source project MZmine provides a new window into the chemical space that surrounds us and lives within. The latest advances in <a href="http://mzmine.github.io/">MZmine 3</a> are now published in a <a href="https://www.nature.com/articles/s41587-023-01690-2">Nature Biotechnology</a> paper.</strong></p>
<h3><strong>Challenges of biochemical analysis</strong></h3>
<p><strong>Analytical chemists of the world, unite!</strong> This paraphrase could characterize the joint efforts of scientists across the globe, who, using the <strong>methods of mass spectrometry</strong>, strive to decipher and analyze the chemical composition of complex samples from various origins, especially in biological and clinical studies. Each individual sample can contain hundreds of thousands of different chemical compounds that scientists need to trace, quantify, and identify to understand their impact on human health or their ecological role.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UOCHB_Robin_Schmid_Pocet_spustni_modulu_M_Zmine_v_letech_2017_2022_152c3eae85/UOCHB-Robin-Schmid-Pocet-spustni-modulu-MZmine-v-letech-2017-2022.jpg" alt="IOCB Prague/Robin Schmid: MZmine module runs in 2017–2022 (in millions)"/></p>
<p>Even relatively small studies result in gigabytes of ‘raw’ data to be processed and interpreted. It is the <strong>processing</strong>, <strong>analysis</strong>, and <strong>comparison</strong> of a multitude of molecular data that constitutes some of the most challenging steps in biochemical analysis today. This is also a major bottleneck that limits the ability of scientists to expand knowledge and come up with exciting new discoveries.</p>
<h3><strong>Community-driven development</strong></h3>
<p>For this reason, a group of international scientists started in 2005 to develop the <strong>open-source software MZmine</strong> to aid <strong>the analysis of mass spectrometry data</strong>. The community developing this software has been co-established by Czech scientist <a href="https://pluskal.group.uochb.cz/en"><strong>Tomáš Pluskal</strong></a>, who has been coordinating the project almost since its inception and is currently a group leader at IOCB Prague.</p>
<p><em>“The greatest strength of the MZmine project is the international community of experts that has formed around the project. At conferences, presentations on MZmine are always well received,”</em> says <strong>Tomáš Pluskal</strong> about the project.</p>
<p><strong>Robin Schmid from IOCB Prague</strong> and <strong>UC San Diego (CA, USA)</strong>, one of the first authors of the paper, adds: <em>“It&#39;s fantastic when we meet researchers from other countries for the first time and they tell us that MZmine and our support has saved their PhD thesis or projects. That&#39;s the best appreciation one can hope for.”</em></p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UOCHB_Tomas_Bellon_Tomas_Pluskal_vlevo_a_Robin_Schmid_oba_z_UOCHB_92138f0c1d/UOCHB-Tomas-Bellon-Tomas-Pluskal-(vlevo)-a-Robin-Schmid-(oba-z-UOCHB).jpg" alt="IOCB Prague/Tomáš Belloň: Tomáš Pluskal (left) and Robin Schmid (both from IOCB Prague)"/></p>
<p>The first version of MZmine has enabled scientists <strong>to automate the processing of datasets generated by analytical devices</strong> at an unprecedented scale. The second generation of MZmine, released in 2010, made the project more widely known and led to the formation of a worldwide community of researchers using the software and continuing to expand its functions with additional modules and applications. The publication introducing the second generation of MZmine has since collected more than <strong>2,200 citations in scientific articles</strong> and the tool itself <strong>has been used to process millions of different measurements</strong>.</p>
<h3><strong>Third generation</strong></h3>
<p>The newest <strong>MZmine 3</strong> brings several major improvements. Whereas the previous version allowed scientists to analyze hundreds of samples in a matter of days, the new generation makes it possible <strong>to process thousands of samples per hour</strong>. Besides vastly <strong>accelerating data processing</strong>, the new version of the software can also be used, for the first time, <strong>to link different data types</strong>, especially time-resolved and imaging data.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UOCHB_Nature_Biotechnology_M_Zmine_open_source_komunitni_projekt_pro_integrativni_zpracovani_dat_LC_IMS_MS_a_IMS_MS_6d9b3759d1/UOCHB-Nature-Biotechnology-MZmine-open-source-komunitni-projekt-pro-integrativni-zpracovani-dat-LC-IMS-MS-a-IMS-MS.jpg" alt="IOCB PRague/Nature Biotechnology: MZmine, an open-source community project for integrative LC–IMS–MS and IMS–MS data processing"/></p>
<p>This opens up opportunities for researchers to more easily <strong>analyze</strong> and <strong>interpret complex biological samples</strong>. MZmine is a tool <strong>to investigate the causes</strong> and <strong>mechanisms of diseases</strong>, <strong>detecting useful clinical biomarkers for diagnostics</strong> and <strong>identifying chemicals</strong> in the environment. This includes previously unknown chemical structures, which might prove valuable for <strong>the discovery and development of new drugs</strong> for medical applications.</p>
<p>The third generation of MZmine was announced in a paper prepared, besides Tomáš Pluskal as the corresponding author, by the first authors Robin Schmid (IOCB Prague and UC San Diego), and Steffen Heuckeroth and Ansgar Korf (both from University of Münster, Germany), joined by over three dozen other contributors from around the world.</p>
<p><em>“MZmine has established itself as a trusted tool for mass spectrometry researchers over the past decade. Its modular framework has fostered community participation in the development of the MZmine code, leading to significant advancements featured in the newly released MZmine 3,”</em> says <strong>Ansgar Korf of University of Münster</strong>.</p>
<p>The development of the MZmine project has been supported by the Czech Science Foundation (project No. 21-11563M).</p>
<ul>
<li>Literature for using the MZmine software <a href="https://lcms.labrulez.com/library?search=MZmine"><strong>in the LabRulezLCMS library</strong></a></li>
<li>Literature for using the MZmine software <a href="https://gcms.labrulez.com/library?search=MZmine"><strong>in the LabRulezGCMS library</strong></a></li>
</ul>


A breakthrough in big data processing helps trace chemicals in complex mixtures

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is the international joint scientific meeting to share recent developments, exchange ideas, explore new directions and initiate a possible collaboration in the analytical spectrometry area.

ESAS

The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) is a leading scientific institution in the Czech Republic, recognized internationally. Its primary mission is basic research in the fields of chemical biology and medicinal chemistry, organic and material oriented chemistry, chemistry of natural compounds, biochemistry and molecular biology, physical chemistry, theoretical chemistry, and analytical chemistry. 

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

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A breakthrough in big data processing helps trace chemicals in complex mixtures

Webinars LabRulezICPMS Week 10-11/2023

Webinars LabRulezICPMS Week 9/2023

Webinars LabRulezICPMS Week 8-9/2023

Webinars LabRulezICPMS Week 7-8/2023

Czech Museum of Mass Spectrometry

ESAS-CSSC 2022 (Day 5)

Webinars LabRulezICPMS Week 6-7/2023

Webinars LabRulezICPMS Week 5-6/2023

Webinars LabRulezICPMS Week 2-3/2023

Upcoming events

Goldschmidt 2026

Optimizing performance of your Thermo Scientific Neoma (MS/MS) MC-ICP-MS System

10th EuChemS Chemistry Congress (ECC10)

Webinars

Automated Elemental Analysis of Lithium Brines by ICP-OES

Get hooked on automated buffer exchange with Lil’ Tuna

Now You See It! Rapid Sample Analysis with 100 MHz Benchtop NMR