The international standard ISO/IEC 17025 [1] clause 7.7.2 with regards to ensuring the validity of results, requires a laboratory to participate in proficiency testing (PT) and/or to participate in interlaboratory comparisons (ILCs) other than PT. However, no guidance as to what these other ILCs might be, or indeed how they might compare in relation to PT, is provided. This leaflet aims to outline other ILCs available, pointing out some of the limitations as compared to PT.&nbsp;There are three major types of ILCs in which a group of laboratories analyses identical portions from a homogeneous, stable test sample, with each type being characterized by its intended purpose [2,3]:<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Interlaboratory_comparisons_other_than_proficiency_testing_2_d9263807fb.jpg" alt="Eurachem: Interlaboratory comparisons other than proficiency testing" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Interlaboratory_comparisons_other_than_proficiency_testing_2_d9263807fb.jpg 245w," sizes="100vw" width="1507" height="607">A key point is that PT is an ILC that is designed to specifically evaluate the performance of participants, providing them with an infrastructure to monitor and assess the validity of their results. This is not the key purpose of the two other ILCs, and thus depending on their intended purpose they have a number of limitations that laboratories need to be aware of when using them rather than PT. Only proficiency testing should have been conducted in full compliance to the competency standard ISO/IEC 17043 [4].&nbsp;<h4>Evaluation of measurement procedure performance&nbsp;</h4>These ILCs, are designed to assess how a particular measurement procedure performs and whether it is fit for its intended purpose. These ILCs are often referred to as a ‘method performance study’ or a ‘collaborative study’ [2]. Some limitations of using such ILCs for monitoring laboratory performance as an alternative to PT are:&nbsp;<ul><li>All participants use the same measurement procedure i.e. the measurement procedure that is being validated. Unless the measurement procedure is being routinely used by the participating laboratory such an ILC will not assess the routine performance of the laboratory using their own routine measurement procedure. Nor does it enable them to compare their performance with other laboratories using alternative measurement procedures.&nbsp;</li><li>The measurement procedure is likely to be new, so participants may not have established stable procedures and quality control, so performance may not reflect routine use.&nbsp;</li><li>The report from such an ILC would not provide information on the performance of the participant, if the statistical model used makes the assumption that all laboratories perform with equal variability.</li><li>The design of the study may require the participants to assess multiple samples and/or to undertake multiple replicate analysis on the test materials. This may not be representative of the routine measurements or tests undertaken by the laboratory.&nbsp;</li><li>The conclusion of the ILC might be that the measurement procedure being assessed is not valid.&nbsp;</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Interlaboratory_comparisons_other_than_proficiency_testing_3_a53ecd2f5d.jpg" alt="Eurachem: Interlaboratory comparisons other than proficiency testing" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Interlaboratory_comparisons_other_than_proficiency_testing_3_a53ecd2f5d.jpg 157w," sizes="100vw" width="570" height="566"><h4>Characterisation of candidate reference materials&nbsp;</h4>These are ILCs that assign a property value to a candidate reference material, usually with a stated measurement uncertainty. These are often referred to as a ‘material certification study’ [2]. Limitations of using such ILCs as an alternative to PT are:&nbsp;<ul><li>The analysis of the candidate reference material is likely to require additional care in exercising the routine measurement procedure, such as substantially more replication, and/or may require quite different reporting formats (e.g. all valid replicates instead of a mean result). Thus, such an ILC will not necessarily provide an evaluation of the performance of the laboratory based on the routine use of their measurement procedures.&nbsp;</li><li>The report from such an ILC may include the results from the participating laboratories but would not provide information on the performance of each laboratory.&nbsp;</li><li>Participating laboratories may be required to assess multiple samples and/or to undertake multiple replicate analysis on the candidate reference materials. Thus this may not be representative of the routine measurements or tests undertaken by the laboratory.&nbsp;</li></ul><h4>Other ILCs&nbsp;</h4>Some other ILCs, whilst not being conducted in full compliance of the requirements of ISO/IEC 17043, may be designed to evaluate participant performance. These would include small ILCs as defined by EA‑2/21 [5] or split sample ILCs i.e. where a portion of a single sample is sent to two or three laboratories. Whilst these ILCs are specifically designed to evaluate participant performance, they may not provide a comprehensive comparison that a PT might provide. In such cases the laboratory needs to evaluate carefully the competence of the organization managing the ILC and the suitability of the service externally provided (ISO/IEC 17025 clause 6.6).

Interlaboratory comparisons other than proficiency testing

Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 29th June 2026? Check out new documents from the field of spectroscopy/spectrometry and related techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">LabRulezGCMS</a> libraries.</blockquote>This week we bring you application notes by Agilent Technologies and Thermo Fisher Scientific and brochure by Shimadzu!<h3>1. Agilent Technologies: Analysis of High Purity Titanium Using an <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=9500">Agilent 9500 ICP-QQQ</a></h3>Ensuring purity and performance of titanium materials used in high-tech industries&nbsp;<ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_high_purity_titanium_9500_icp_qqq_5994_9024en_agilent_56ab5e943b.pdf">Full PDF for download</a></li></ul><h5>Importance of high-purity titanium and the role of ICP-QQQ&nbsp;</h5>High-purity titanium (Ti) is a critical material in high-tech industries such as semiconductor manufacturing and aerospace engineering. In semiconductor applications, Ti is widely used as a sputtering target for thin-film deposition, where even trace levels of impurities can negatively affect film uniformity, electrical properties, and device reliability. In aerospace applications, Ti is valued for its high strength-to-weight ratio and corrosion resistance, making it an ideal material for engine components and structural parts. However, any impurities can compromise the mechanical integrity and diminish the long-term performance of components, especially when operating under extreme conditions.Ensuring the reliability and functionality of Ti in these demanding environments requires precise quantification of trace impurities in the raw material. Triple quadrupole Inductively Coupled Plasma Mass Spectrometry (ICP-QQQ) provides robust suppression of spectral interferences and ultra-low detection limits (DLs), enabling accurate determination of impurities at or below the 1 mg/kg (ppm) level in the solid. This level of sensitivity is particularly important for quality control (QC) of high-purity Ti, where conventional techniques such as XRF, ICP-OES, and GD-MS lack the sensitivity and DLs.&nbsp;For unrivalled interference reduction using reactive cell gases, Agilent ICP-QQQ instruments include two unit mass (1 u) quadrupole mass filters, Q1 and Q2.1 Q1 is positioned before the collision/reaction cell (CRC) to select which ions enter the cell for reaction with the cell gas. Q2 filters ions that exit the cell before they pass to the detector. This tandem mass spectrometer (MS/MS) operation allows for unmatched control of reaction chemistry in the CRC, making the technique useful for handling intense spectral interferences, including polyatomic, doubly charged ion (M++), isobaric, and peak overlap interferences.&nbsp;Using the newly developed <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=9500">Agilent 9500 Triple Quadrupole ICP-MS</a> featuring a Dual-Cell System (DCS) CRC and equipped with an optional m-lens, analysts can confidently analyze Ti matrix samples and verify material purity over extended measurement periods. The m-lens is designed with an optimized geometry that minimizes background signals from easily ionized elements that can deposit on interface components during long runs. This feature enables the instrument to maintain high-power, matrix-tolerant plasma conditions while achieving ultralow background equivalent concentrations (BECs), which is critical for ppt-level impurity analysis. Operating the DCS with a suitable cell gas effectively controls spectral interferences from Ti-based species (Ti²+ and TiO+ ) that impact elements like sodium (Na), magnesium (Mg), copper (Cu), and zinc (Zn). Together with the m‑lens, this approach ensures accurate measurement of trace elemental impurities, enabling compliance within stringent industry standards. The effectiveness of the m‑lens in minimizing background signals and enabling ppt‑level impurity analysis under robust plasma conditions has also been demonstrated in high-matrix applications using ICP‑QQQ.2, 3 In addition to interference control, the 9500 ICP-QQQ system’s robustness and reproducibility make it well suited for routine analysis in both research and production settings. This capability supports the continued advancement of high-tech applications that rely on ultra-clean titanium.In this study, a 200 ppm Ti solution prepared from a high-purity Ti powder was used to represent a typical sample encountered in advanced material analysis. The performance of the 9500 ICP-QQQ for quantifying trace impurities, including Na, Mg, Cu, and Zn, in a high Ti matrix was assessed through spike-recovery experiments and long-term stability tests.<h4>Conclusion&nbsp;</h4>This study demonstrated the effectiveness of the Agilent 9500 ICP-QQQ with m-lens for the ultra-trace analysis of impurity metals in high-purity titanium. By applying optimized reaction gas conditions and mass-shift techniques, spectral interferences from Ti-based species such as Ti²+ and TiO+ were successfully mitigated, enabling accurate quantification of elements like Mg, Cu, and Zn.&nbsp;The method achieved limits of quantification in the sub-ppm range for the undiluted Ti digestion solution and maintained stable ISTD signals over extended measurement periods. Spike recovery tests confirmed high accuracy and reproducibility, with most elements showing recoveries within ±10% and RSDs below 3%.&nbsp;These results confirm that the 9500 ICP-QQQ is a robust and reliable tool for quality control of high-purity Ti, supporting its critical applications in semiconductor and aerospace industries where impurity levels must be strictly controlled.<h3>2. Shimadzu: Scanning Probe Microscope /Atomic Force Microscope SPM-9700HT Plus</h3><ul><li>Brochure</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/c147_e021_4c550d3be3.pdf">Full PDF for download</a></li></ul>The Shimadzu SPM-9700HT Plus is a high-throughput scanning probe microscope (SPM) / atomic force microscope (AFM) designed for three-dimensional surface imaging and nanoscale characterization of material properties across a broad range of scientific and industrial applications. The system combines high-resolution topographical imaging with multiple AFM measurement modes, including contact, dynamic, phase, lateral force, force modulation, and force-curve measurements, while optional modules extend its capabilities to techniques such as Kelvin probe force microscopy (KPFM), magnetic force microscopy (MFM), conductive AFM, piezoresponse force microscopy (PFM), and scanning tunneling microscopy (STM). A wide selection of interchangeable scanners, environmental accessories, optical microscope units, and specialized sample holders enables the instrument to be configured for diverse analytical requirements.A major focus of the brochure is the system's emphasis on automation and ease of use through Shimadzu's Analytical Intelligence technology. Features such as Observation Navigation, NanoAssist, and the optional Cantilever Master automate instrument setup, cantilever installation, optimization of imaging parameters, and measurement workflows, allowing operators with varying levels of experience to acquire high-quality, reproducible AFM data. The redesigned control electronics and scanning system also enable high-throughput imaging and rapid physical property mapping while maintaining nanoscale resolution. In addition, the head-slide mechanism simplifies sample exchange without removing the cantilever, increasing productivity during routine measurements.Beyond surface topography, the SPM-9700HT Plus provides extensive quantitative analysis capabilities through integrated software for roughness measurements, particle analysis, cross-sectional profiling, and morphological characterization. Optional Nano 3D Mapping Fast technology extends the instrument to nanoscale mechanical property measurements by performing force-curve mapping, allowing localized evaluation of adhesion, Young's modulus, and other mechanical properties of thin films, polymers, biomaterials, and soft samples. The optional Particle Analysis Software further enables automated extraction, classification, statistical evaluation, and export of particle size and morphology data for large datasets.The brochure demonstrates the versatility of the platform through numerous application examples spanning electronics, semiconductor devices, magnetic materials, life sciences, industrial materials, batteries, polymers, nanomaterials, food science, and chemistry. Representative studies include magnetic domain imaging, organic thin-film transistor characterization, collagen and DNA visualization, live-cell imaging, lithium-ion battery electrode and separator analysis, photocatalyst surface potential measurements, polymer phase imaging, cellulose nanofiber characterization, and beer yeast morphology. Together, these examples highlight the Shimadzu SPM-9700HT Plus as a comprehensive AFM platform capable of combining rapid imaging, advanced nanoscale property mapping, and automated data analysis for both research and routine industrial quality control.<h3>3. Thermo Fisher Scientific: Enhancing Monoclonal Antibody Yield and Quality Through Automated Multi-Component Feedback Control Loops Using the MarqMetrix All-In-One Process Raman Analyzer</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/enhancing_monoclonal_antibody_an1506_en_bba763e865.pdf">Full PDF for download</a></li></ul>The application of Raman spectroscopy for real-time monitoring and control of bioreactors marks a significant advancement in bioprocessing technology. Over the past decade, its adoption has enabled tighter control of critical process parameters (CPPs), offering early indicators of process performance to ensure consistency and improve product quality. Raman spectroscopy leverages the unique vibrational signatures of molecules, allowing for highly specific detection even in complex biological matrices. This enables simultaneous, real-time monitoring of multiple CPPs, including nutrient concentrations, metabolic by-products, and cell density. As a result, users gain deep, real-time insights into cellular metabolism and can implement more dynamic, adaptive feeding strategies based on metabolic network understanding.&nbsp;Previous studies have demonstrated the negative impact of high lactate on cell health and quantity and quality of titer produced.² In this study, we demonstrate the successful implementation of process Raman analyzer for simultaneous multi-component feedback control of glucose and lactate in a bioreactor. By continuously monitoring both analytes, the feedback control loop dynamically maintained a constant total carbon concentration (glucose + lactate) at a setpoint of 2 g/L.&nbsp;This advanced carbon-source-based control strategy ensured that cellular metabolic demands were met while promoting lactate consumption toward the end of the run. As a result, lactate accumulation was significantly reduced, leading to substantial improvements in titer yield, product quality, and cell viability compared to standard bolus feeding strategies (Figure 2).The outcomes of this work underscore the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2233">Thermo Scientific™ MarqMetrix™ All-In-One Process Raman Analyzer </a>as a key Process Analytical Technology (PAT) tool-enabling real-time, multi-analyte control for any biomanufacturer seeking to engage in intelligent, automated biomanufacturing.<h4>Conclusion&nbsp;</h4><h5>1. Unmatched Real-Time Control Capability:&nbsp;</h5>Maintaining a constant total carbon concentration (glucose + lactate) of 2 g/L in dynamic bioreactor environments demands precise, simultaneous analyte monitoring. The MarqMetrix All-In-One Process Raman Analyzer delivers near real-time, high-fidelity data every two minutes, empowering advanced control strategies that are simply not feasible with conventional technologies. This makes it an indispensable PAT tool for modern bioprocessing.&nbsp;<h5>2. Proven Impact on Product Yield and Quality:&nbsp;</h5>The Raman-enabled carbon control strategy resulted in a &gt;10% increase in titer and a reduction in glycation by 83% and 66% compared to continuous and fed-batch glucose control, respectively. These outcomes underscore the analyzer’s transformative impact on both product quantity and quality.&nbsp;<h5>3. Versatile Automation Across Bioprocesses:&nbsp;</h5>All three bioreactor runs—each employing distinct control logics (Table 2)—were successfully managed through automated feedback using the process Raman analyzer. Its flexible design, including easily swappable probes, supports seamless adaptation to other critical metabolites such as amino acids, making it a universal solution for bioprocess control.&nbsp;<h5>4. Foundation for Intelligent Manufacturing:&nbsp;</h5>With its real-time, data-rich insights and seamless integration into automated systems, the MarqMetrix All-InOne analyzer is not just a monitoring tool; it is a cornerstone technology for intelligent, AI-driven biomanufacturing. It enables consistent, high-quality production while reducing time, cost, and variability.

News from LabRulezICPMS Library - Week 27, 2026

Scientists from CEITEC Brno University of Technology led by Markéta Kaiser have achieved a globally unique breakthrough in coral research. Using the live microCT method, they were able, for the first time ever, to observe the growth of living marine corals in real time and reveal the processes behind the formation of their calcium carbonate skeletons, which had previously remained hidden beneath the surface. The results of the international study, published in the prestigious journal Science Advances, show how corals grow, regenerate, and respond to stress and competing organisms.The <a target="_blank" rel="noopener noreferrer" href="https://www.science.org/doi/10.1126/sciadv.aee3183">study</a> was carried out through a collaboration between researchers from Brno, Vienna, and several other international institutions. A key role was played by the X-ray Micro and Nano Computed Tomography Laboratory (CTLAB) at CEITEC BUT, where all the crucial data and three-dimensional coral models were produced. CEITEC also shares both the first and corresponding authorship of the study.“Thanks to live microCT, we were able, for the first time, to observe what happens beneath the surface of a coral skeleton,” explains Markéta Kaiser from CTLAB at CEITEC BUT. “For example, we witnessed situations where a coral, after being attacked by algae, completely halted its normal growth and began building a protective wall around the threatened area. Once the danger had passed, it was able to resume its original growth pattern.”<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_540e183e84.jpeg" alt="CEITEC BUT/Jakub Rozboud: Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life: Markéta Kaiser, CTLAB CEITEC at CEITEC BUT." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_540e183e84.jpeg 235w," sizes="100vw" width="1600" height="1067">The scientists successfully captured coral growth both vertically and horizontally, the formation of protective barriers against competing organisms, and regeneration mechanisms following damage.The research was exceptionally demanding from a technological standpoint. The team had to develop a special system that enabled living corals to be safely scanned directly in seawater. The coral colonies regularly traveled by train from Vienna to Brno for measurements and, after several hours, were transported back to professional aquarium systems in Vienna.“At first, it seemed like a somewhat crazy idea. No one knew whether living corals could withstand repeated scanning,” says Kaiser. “Gradually, however, we found that they survived, continued to grow, and provided us with unique data.”<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_2_fcbb29a4f6.jpeg" alt="CEITEC BUT/Jakub Rozboud: Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life: Markéta Kaiser is placing a coral sample into CT for scanning." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_2_fcbb29a4f6.jpeg 235w," sizes="100vw" width="1600" height="1067">The original concept for the project came from developmental biologist Igor Adameyko of the Medical University of Vienna, who proposed combining marine biology with advanced imaging technologies more commonly used in engineering and technical fields.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_3_8c5f376f41.jpeg" alt="CEITEC BUT/Markéta Kaiser: Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life: Corals CT - 1." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_3_8c5f376f41.jpeg 228w," sizes="100vw" width="1600" height="1096">The findings of the Brno researchers have already attracted the attention of experts in Okinawa, Japan, who specialize in coral reef research. They plan to use the live microCT method to study the effects of light, photosynthesis, and environmental changes on coral growth.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_4_445c1cc3b7.jpeg" alt="CEITEC BUT/Markéta Kaiser: Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life:Corals CT - 2." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_4_445c1cc3b7.jpeg 245w," sizes="100vw" width="1600" height="988">According to the researchers, the project demonstrates the importance of interdisciplinary collaboration between engineering and biological sciences. The research could contribute not only to the study and conservation of coral reefs, but also to fields such as paleontology and materials science.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_5_514ee9c974.jpg" alt="CEITEC BUT/Markéta Kaiser: Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life: Corals CT - 3." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_5_514ee9c974.jpg 143w," sizes="100vw" width="1600" height="1750"><blockquote><h4>Original Article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://www.science.org/doi/10.1126/sciadv.aee3183">Coral growth, retraction, defense, and regenerative strategies revealed by live microCT</a></h4>Karina Araslanova, Marketa Kaiser, Anton Fetisov, Diana Gavrik, Tomas Zikmund, Daniel Abed-Navandi, Karel Katovský, Jozef Kaiser, Igor AdameykoSci. Adv., 2026, 12, eaee3183<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1126/sciadv.aee3183">https://doi.org/10.1126/sciadv.aee3183</a><h6>licenced under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote><h4>Abstract</h4>Understanding how corals build and remodel their skeletons is key to explaining reef resilience, yet most insights come from static imaging. Using longitudinal live microCT, we tracked the same coral colonies over weeks to months at micrometer resolution. Coral skeleton formation is not a uniform accretion process but a dynamic integration of multiple programs, including vertical and horizontal patterned growth, previously undescribed defensive wall-building against competitors, exploratory edge behavior with reversible expansions and retractions, and skeletal regeneration favoring rapid, imprecise yet effective matrix expansion. Time-resolved imaging links colony-scale growth to microscale events, showing that all modes depend on balances between fusion of skeletal microparticles and layered matrix deposition, guided by tissue prepatterning. Beyond corals, this framework generalizes to studying skeletal dynamics across diverse biomineralizing organisms.

Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life 

Article

Application

Academy

Science and research

Since its establishment in 2011, CEITEC has quickly developed into a cutting-edge infrastructure for research which performs highly alongside the best institutes in Europe. Among the main priorities of CEITEC are the promotion of a motivating and dynamic international scientific environment, the provision of state-of-the-art research infrastructure, and the policy of open communication and equal opportunities.

CEITEC

Eurachem is a European network promoting international traceability of chemical measurements and good analytical practice. It provides expert guidance, supports method validation, uncertainty evaluation, proficiency testing, and facilitates discussion on technical and policy issues in analytical quality.

Eurachem

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Thermo Scientific™ iCAP™ RQ ICP-MS

Compact, robust SQ-ICP-MS for high-throughput labs. Offers excellent interference removal, low detection limits, and intuitive automation across diverse sample matrices.

Robust single-quadrupole ICP-MS for high-throughput laboratoriesThe iCAP RQ ICP-MS is a compact, high-performance inductively coupled plasma mass spectrometer that combines robustness, ease of use, and exceptional analytical capabilities for routine laboratories. With intuitive workflows, minimized maintenance, and advanced interference removal technology, it delivers confident multi-element analysis across a wide range of challenging matrices.<h3>Key Features and Benefits</h3><h4>⚙️ Robust Hardware Design</h4><ul><li>Tolerates high-matrix samples (e.g., seawater, organic solvents)</li><li>Reliable plasma performance even with 100% acetonitrile</li><li>Advanced thermal management for long-term mass stability</li><li>Solid-state RF generator and durable electronics</li></ul><h4>🚀 High Productivity</h4><ul><li>‘Get Ready’ one-click setup automates startup</li><li>Cone replacement in as little as 60 seconds</li><li>Quick-connect sample introduction components</li><li>Supports 24/7 operation with minimal downtime</li></ul><h4>🎯 Exceptional Analytical Accuracy</h4><ul><li>Single quadrupole with He KED and QCell LMCO for interference removal</li><li>Detects elements like Li and Be at sub-ppt levels</li><li>Flexible interfaces for robust, matrix-tolerant, or high-sensitivity needs</li><li>High ion transmission with low background</li></ul><h4>🧠 Smart Software – Qtegra ISDS</h4><ul><li>Streamlined method development with visual interface</li><li>Compliance-ready with 21 CFR Part 11 features</li><li>Integrated QA/QC protocols reduce re-runs</li><li>Autosampler and valve compatibility, LIMS support, custom reporting</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Thermo_Scientific_ICP_MS_i_CAP_RQ_Hmotnostni_spektrometr_s_indukcne_vazanym_plazmatem_4f1c97ac70.jpg" alt="Thermo Scientific™ iCAP™ RQ ICP-MS" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Pragolab_Thermo_Scientific_ICP_MS_i_CAP_RQ_Hmotnostni_spektrometr_s_indukcne_vazanym_plazmatem_4f1c97ac70.jpg 160w," sizes="100vw" width="782" height="764"><h3>Advanced Workflow Capabilities</h3><ul><li>Argon Gas Dilution (AGD): Direct high-matrix sample analysis</li><li>Autodilution: Intelligent calibration and automated sample prep</li><li>Speciation: Full IC, LC, and GC integration via ChromControl plug-in</li><li>Laser ablation: Supports depth/spatial solid sample profiling</li><li>Single particle analysis: Accurate spICP-MS using npQuant module</li></ul><h3>Application Areas</h3><ul><li>Environmental: Drinking water, wastewater, soils (e.g., EPA 200.8)</li><li>Pharmaceutical: Elemental impurities (ICH Q3D, USP 232/233)</li><li>Food safety: Simultaneous toxic/essential element screening</li><li>Clinical research: Trace-level element detection in complex matrices</li><li>Geosciences: Rock digests, lithium borate fusions</li><li>Industry &amp; materials: Alloys, advanced materials, nuclear isotopic ratios</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Thermo_Scientific_ICP_MS_i_CAP_RQ_Hmotnostni_spektrometr_s_indukcne_vazanym_plazmatem_2_4c27c3a2d0.jpg" alt="Thermo Scientific™ iCAP™ RQ ICP-MS" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Pragolab_Thermo_Scientific_ICP_MS_i_CAP_RQ_Hmotnostni_spektrometr_s_indukcne_vazanym_plazmatem_2_4c27c3a2d0.jpg 245w," sizes="100vw" width="2291" height="1391">

Thermo Scientific Nicolet iS 10 FTIR Spectrometer

Nicolet iS10 FTIR spectrometer for mid-IR analysis with high resolution, DTGS detector, sealed optics, and broad accessory compatibility.

The Thermo Scientific Nicolet™ iS™ 10 FTIR Spectrometer is a high-performance infrared spectrometer designed for routine and advanced analytical applications in QA/QC, pharmaceuticals, polymers, forensics, and petrochemical analysis.The system is optimized for the mid-infrared (mid-IR) region, utilizing a KBr/Ge beamsplitter, with optional XT-KBr/Ge extended range optics. It is equipped with a fast recovery DTGS detector, providing high sensitivity and stability without the need for liquid nitrogen cooling.A sealed optical bench ensures resistance to ambient humidity, supporting reliable long-term operation. The modular design allows integration with a wide range of accessories including SMART accessories, microscopes, and TGA-IR systems.<h4>Key Features</h4><ul><li>FTIR spectrometer optimized for mid-IR analysis</li><li>Spectral range up to 11,000–350 cm⁻¹ (XT optics)</li><li>High resolution &lt; 0.4 cm⁻¹</li><li>DTGS detector (no liquid nitrogen required)</li><li>KBr/Ge beamsplitter (standard)</li><li>Sealed optics for humidity resistance</li><li>Dual source (Ever-Glo + tungsten/halogen)</li><li>Compatibility with wide accessory range (SMART, microscopy, TGA-IR)</li><li>USB connectivity</li><li>ASTM E1421 compliant (ISO/GLP)</li></ul><h3>Technical Specifications</h3><h4>Optics and Performance</h4><ul><li>Spectral range:<ul><li>7800–350 cm⁻¹ (standard KBr)</li><li>11,000–375 cm⁻¹ (XT-KBr extended range)</li></ul></li><li>Spectral resolution: &lt; 0.4 cm⁻¹</li><li>Laser: HeNe</li><li>Beamsplitter:<ul><li>KBr/Ge (standard)</li><li>XT-KBr/Ge (optional)</li></ul></li></ul><h4>Detection and Sources</h4><ul><li>Detector:<ul><li>DTGS (standard)</li><li>MCT (optional, LN₂ cooled)</li></ul></li><li>Source:<ul><li>Mid-IR Ever-Glo</li><li>Tungsten/halogen</li></ul></li></ul><h4>Construction and Compatibility</h4><ul><li>Optical system: sealed</li><li>Compatible with:<ul><li>SMART Accessories</li><li>Continuum microscope</li><li>TGA-IR</li><li>Photoacoustic modules</li><li>standard FTIR accessories</li></ul></li></ul><h4>Interface</h4><ul><li>USB 2.0</li></ul><h4>Dimensions and Weight</h4><ul><li>Width: 570 mm</li><li>Height: 250 mm</li><li>Depth: 550 mm</li><li>Weight: 33 kg</li></ul><h4>Validation</h4><ul><li>ASTM E1421</li><li>ISO / GLP compliance</li></ul>

Thermo Scientific Nicolet iS50 FTIR Spectrometer

The Nicolet iS50 FTIR spectrometer provides a modular platform for ATR, Raman, NIR, and GC-IR analysis with automation and a wide spectral range.

The Thermo Scientific™ Nicolet™ iS50 is a highly flexible FTIR spectrometer designed as a comprehensive materials analysis platform. It enables a wide range of measurements within a single system—from routine material identification to advanced multi-technique analysis.Its modular architecture allows seamless expansion with Raman, NIR, or GC-IR modules, enabling multiple analytical techniques without reconfiguring the instrument. The Automated Beamsplitter Exchanger (ABX) enables switching between spectral ranges without manual intervention or disruption of optics or purge conditions.The system supports fully automated workflows through Touch Point operation, allowing setup, data collection, and reporting with a single click. An optional built-in diamond ATR module enables immediate measurement without sample preparation while keeping the main sample compartment available for other analyses.The Nicolet iS50 is ideal for pharmaceuticals, forensics, polymers, food analysis, and general laboratories where speed, reproducibility, and analytical flexibility are essential.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Nicolet_i_S50_FTIR_Spectrometer_3_43e1a1a943.jpg" alt="Thermo Scientific Nicolet iS50 FTIR Spectrometer " srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Nicolet_i_S50_FTIR_Spectrometer_3_43e1a1a943.jpg 173w," sizes="100vw" width="488" height="440"><h3>Key Features</h3><ul><li>Automated Beamsplitter Exchanger (ABX)</li><li>Modular system: Raman, NIR, GC-IR</li><li>Built-in diamond ATR for instant, no-prep analysis</li><li>Automated workflows (Touch Points)</li><li>Wide spectral range (FIR–VIS)</li><li>Up to 9 user-selectable detectors</li><li>Multi-technique integration in a single workflow</li><li>Compatibility with SMART accessories</li></ul><h3>Technical Specifications</h3><ul><li>Spectral range: 15 – 27,000 cm⁻¹</li><li>Resolution: better than 0.09 cm⁻¹</li><li>Source: Polaris™ IR + tungsten-halogen source</li><li>Laser: HeNe</li><li>Detectors: up to 9 selectable</li><li>Interface: USB 2.0</li><li>Power: 100/240 V, 50/60 Hz</li><li>Dimensions (W × D × H): 62.6 × 69.8 × 27.6 cm</li><li>Weight: 60 kg</li><li>Validation: ASTM E1421, ISO/GLP compliant</li></ul>

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