<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the weeks Weeks 27-29, 2024? Check out new documents from the field of spectroscopy, especially ICP/MS techniques!</strong></p>
<blockquote>
<h4>👉 <a href="https://icpms.labrulez.com/library"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT ICPMS AND RELATED TECHNIQUES</strong></a></h4>
</blockquote>
<blockquote>
<p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a href="https://gcms.labrulez.com/library"><strong>LabRulezGCMS</strong></a> libraries.</p>
</blockquote>
<h4><strong>1. Agilent Technologies: <a href="https://icpms.cz/labrulez-bucket-strapi-h3hsga3/ICP_MS_Intelli_Quant_Analysis_Technical_Overview_f68dc39e11.pdf">Agilent ICP-MS IntelliQuant Analysis</a></strong></h4>
<ul>
<li>Technical Overview: An overview of QuickScan, IntelliQuant, and Star Rating</li>
</ul>
<p><strong>Introduction:</strong> Introduced in Agilent ICP-MS MassHunter version 4.6, IntelliQuant for ICP-MS provides an automated semiquantitative analysis for every sample. Calibration and background correction are automatically made with no user intervention,  and data is presented in an easily understood periodic table heat map format and a comprehensive data table.</p>
<p>IntelliQuant is possible because a QuickScan can be performed when measuring each sample. The optional two second QuickScan acquires a complete mass spectrum of the entire measurable mass range, facilitating semiquantitative and Total Matrix Solids (TMS) calculations of every sample.</p>
<p>TMS levels are calculated from the IntelliQuant data. Similar to Total Dissolved Solids (TDS), TMS is the sum of the key matrix elements in each sample. Included in the TMS calculation are the elements typically considered to contribute to matrix effects, such as ionization suppression and matrix deposition on interface cones and lenses. Gas elements, including elements in acids such as HCl and HNO₃ , do not cause appreciable matrix effects in ICP-MS, so they are excluded from the calculation.</p>
<h4><strong>2. Agilent Technologies: <a href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/po_7850_icpms_elemental_impurities_oligo_asms_2024_mp131_en_agilent_e8292cc884.pdf">Analysis of Elemental Impurities in Synthetic Oligonucleotides by ICP-MS In compliance with USP &lt;232&gt;/&lt;233&gt; and ICH Q3D(R2)/Q2(R1)</a></strong></h4>
<ul>
<li>Poster - ASMS 2024</li>
</ul>
<p><strong>Introduction:</strong> Synthetic oligonucleotides are short chains (oligomers) of deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) molecules. They are used in applications such as polymerase chain reaction (PCR) tests, DNA sequencing and novel therapeutic products.</p>
<p>The synthesis of oligonucleotides involves a four-step cyclic process followed by multi-step downstream purification. This manufacturing process as well as environment, packaging, and container closure systems can be potential sources of contamination leading to inorganic impurities formation.</p>
<p>To control and monitor product safety, permitted daily exposure (PDE) limits of 24 elements are defined in ICH guideline Q3D(R2)1 and USP chapter &lt;232&gt;2 . ICH Q2(R1)3 and USP&lt;233&gt; 4 describe analytical measurement requirements and procedures for the measurement of those elemental impurities. Although oligonucleotide products have not been included in those regulatory guidelines yet, the industry common practice is to follow those guidelines.</p>
<p>In this study, an analytical workflow (Figure1) was developed in accordance with the ICH/USP guidelines for the analysis of elemental impurities in an oligonucleotide sample using an Agilent 7850 ICP-MS. Data was acquired to evaluate the accuracy, specificity, reproducibility, and ruggedness of the method.</p>
<p><strong>Conclusions:</strong> The study has demonstrated the suitability of the Agilent 7850 ICP-MS for the identification and quantification of 24 elements in a synthetic oligonucleotide sample in compliance with existing USP and ICH guidelines. Instrument and method performance requirements for stability, detectability, precision, specificity, ruggedness, accuracy, and spike recovery were all achieved per the criteria given in USP &lt;232&gt;/&lt;233&gt; and ICH Q3D(R2)/Q2(R1).</p>
<p>As the development and use of oligonucleotides in therapeutic applications continue to advance, the elemental impurities analysis of oligonucleotides using 7850 ICP-MS can safeguard the product quality and safety.</p>
<h4><strong>3. Thermo Fisher Scientific: <a href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_002822_tea_icap_rqplus_food_an002822_em_en_7e73327401.pdf">Accurate and reliable multielement analysis of alternative protein foods using ICP-MS</a></strong></h4>
<ul>
<li>Application note - Food safety</li>
</ul>
<p><strong>Goal:</strong> To demonstrate the applicability of the Thermo Scientific™ iCAP™ RQplus ICP-MS instrument for fast and accurate, highly sensitive, and reliable determination of nutritional and toxic trace elements in alternative protein food samples.</p>
<p><strong>Keywords:</strong> ICP-MS, AGD, He-KED, half-mass correction, accuracy, robustness, toxic elements, nutritional elements</p>
<h4><strong>4. Thermo Fisher Scientific: <a href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_002822_tea_icap_rqplus_food_an002822_em_en_7e73327401.pdf">Analysis of process water from hydrogen fuel cells using triple quadrupole inductively coupled plasma mass spectrometry (ICP-MS)</a></strong></h4>
<ul>
<li>Application note - Industrial</li>
</ul>
<p><strong>Goal:</strong> To demonstrate the analysis of process water from hydrogen fuel cells for inorganic trace contaminants with high sensitivity and accuracy using triple quadrupole ICP-MS.</p>
<p><strong>Keywords:</strong> Fluorine, fuel cell, high resolution, ICP-MS, KED, PEM, process water, triple quadrupole, TQ-O₂  mode</p>
<h4><strong>5. Thermo Fisher Scientific: <a href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_002822_tea_icap_rqplus_food_an002822_em_en_7e73327401.pdf">Combining full spectrum read-out and innovative automation capabilities for the robust and fast analysis of major and trace elements in fertilizers using ICP-OES</a></strong></h4>
<ul>
<li>Application note - Environmental</li>
</ul>
<p><strong>Goal:</strong> To demonstrate the capabilities of the Thermo Scientific™ iCAP™ PRO XP ICP-OES Duo instrument, in conjunction with the Thermo Scientific™ iSC-65 Autosampler, for the fast and robust elemental analysis of fertilizers.</p>
<p><strong>Keywords:</strong> ICP-OES, robustness, method validation, sensitivity, Step Ahead, limits of quantitation, analytical testing, toxic elements.</p>


News from LabRulezICPMS Library Weeks 27-29, 2024

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in week 34, 2024? Check out new documents from the field of spectroscopy, especially ICP/MS techniques!</strong></p>
<blockquote>
<h4>👉 <a href="https://icpms.labrulez.com/library"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT ICPMS AND RELATED TECHNIQUES</strong></a></h4>
</blockquote>
<blockquote>
<p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a href="https://gcms.labrulez.com/library"><strong>LabRulezGCMS</strong></a> libraries.</p>
</blockquote>
<p>This week we bring to you a poster from <a href="https://gcms.labrulez.com/events/568"><strong>ASMS 2024</strong></a> by <strong>Agilent Technologies</strong>, applications by <strong>Shimadzu</strong> and <strong>Thermo Fisher Scientific</strong>, and technical note by <strong>Metrohm</strong>!</p>
<h4><strong>1. Agilent Technologies: <a href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/po_7850_icpms_elemental_impurities_oligo_asms_2024_mp131_en_agilent_e8292cc884.pdf">Analysis of Elemental Impurities in Synthetic Oligonucleotides by ICP-MS In compliance with USP &lt;232&gt;/&lt;233&gt; and ICH Q3D(R2)/Q2(R1)</a></strong></h4>
<ul>
<li>poster / <a href="https://gcms.labrulez.com/companies/296"><strong>ASMS 2024</strong></a></li>
</ul>
<p><strong>Introduction:</strong> Synthetic oligonucleotides are short chains (oligomers) of deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) molecules. They are used in applications such as polymerase chain reaction (PCR) tests, DNA sequencing and novel therapeutic products.</p>
<p>The synthesis of oligonucleotides involves a four-step cyclic process followed by multi-step downstream purification. This manufacturing process as well as environment, packaging, and container closure systems can be potential sources of contamination leading to inorganic impurities formation.</p>
<p>To control and monitor product safety, permitted daily exposure (PDE) limits of 24 elements are defined in ICH guideline Q3D(R2)1 and USP chapter &lt;232&gt;2. ICH Q2(R1)3 and USP&lt;233&gt; 4 describe analytical measurement requirements and procedures for the measurement of those elemental impurities. Although oligonucleotide products have not been included in those regulatory guidelines yet, the industry common practice is to follow those guidelines.</p>
<p>In this study, an analytical workflow (Figure1) was developed in accordance with the ICH/USP guidelinesfor the analysis of elemental impurities in an oligonucleotide sample using an Agilent 7850 ICP-MS. Data was acquired to evaluate the accuracy, specificity, reproducibility, and ruggedness of the method.</p>
<p><strong>Conclusion:</strong> The study has demonstrated the suitability of the Agilent 7850 ICP-MS for the identification and quantification of 24 elements in a synthetic oligonucleotide sample in compliance with existing USP and ICH guidelines. Instrument and method performance requirements for stability, detectability, precision, specificity, ruggedness, accuracy, and spike recovery were all achieved per the criteria given in USP &lt;232&gt;/&lt;233&gt; and ICH Q3D(R2)/Q2(R1).</p>
<p>As the development and use of oligonucleotides in therapeutic applications continue to advance, the elemental impurities analysis of oligonucleotides using 7850 ICP-MS can safeguard the product quality and safety.</p>
<h4><strong>2. Metrohm: <a href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/Metrohm_OMNIS_NIRS_An_efficiency_boost_for_your_706048fea4.pdf">OMNIS NIRS: An efficiency boost for your laboratory</a></strong></h4>
<ul>
<li>Technical note</li>
</ul>
<h5><strong>Routine lab analysis – simplified with OMNIS NIRS</strong></h5>
<p>Near-infrared spectroscopy (NIRS) is an analytical technique used to determine multiple parameters in samples quickly without requiring any chemicals. Determinations can be performed in liquids, pastes, and solids with this non-destructive method.</p>
<p>Many industries benefit from using NIRS in their laboratory workflows. Time and cost savings are two of the most convincing arguments for adopting NIRS in the laboratory. It is also easy to use, even for non-technical operators.</p>
<p>This White Paper discusses the concept and benefits of NIR spectroscopy, supplemented with the use of the Metrohm NIR solution, OMNIS NIRS, in several real-life laboratory application examples. Applications from the petrochemical, food and beverage, semiconductor, and pharmaceutical industries are used to demonstrate the unique functionalities of OMNIS NIRS in different situations.</p>
<p><strong>SUMMARY:</strong> With OMNIS NIRS, users get a flexible, modular analytical solution which is suitable for many industries. Unique functionalities include:</p>
<ul>
<li>automatic model development (OMD)</li>
<li>a high measurement speed</li>
<li>the possibility to recognize sample insertion and removal</li>
<li>sophisticated temperature control</li>
<li>the ability to combine different analytical technologies from a single manufacturer—even in an automated system</li>
</ul>
<p>Boost the efficiency of your laboratory with OMNIS NIRS.</p>
<h4><strong>3. Shimadzu: <a href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_00712_en_f0d3971af4.pdf">Analysis of Metal Elements in Culture Medium Using ICPMS-2050</a></strong></h4>
<ul>
<li>Application</li>
</ul>
<p><strong>User Benefits</strong></p>
<ul>
<li>Analysis of both trace and high-concentration elements is possible in culture media.</li>
<li>Culture media can be analyzed with simple dilution-only pretreatment using the ICPMS-2050.</li>
<li>The elements in the culture medium can be analyzed reliably and accurately over a long period.</li>
</ul>
<p><strong>Introduction:</strong> A culture medium usually contains elements spanning a wide range of concentrations, from trace (Co, Cu, Se, etc.) to several thousand ppm (Na). Elementsin the medium are important in cell cultures because they are taken up by the cells and contribute to enzyme activity and redox reactions. On the other hand, it has been pointed out that unexpected contamination from raw materials and equipment in the culture media manufacturing process may cause differences in element concentrations among batches. Therefore, it is important to know the element concentration profiles in the culture medium to achieve a homogeneous cell culture. </p>
<p>ICP-MS issuitable for this purpose because it can analyze multiple elements with high sensitivity and has a wide dynamic range. In this Application News, an ICPMS-2050 was used to analyze both trace and high-concentration elements in a culture medium by dilution-only pretreatment. Furthermore, the spike recovery and long-term stability in the culture medium were evaluated using the ICPMS-2050 to confirm that there was no effect on the analytical value due to dilution-only pretreatment.</p>
<p><strong>Summary:</strong> In this Application News, the ICPMS-2050 was used to analyze trace and high-concentration elements in a culture medium using dilution-only pretreatment. Good spike recoveries were obtained for all the measured elements, verifying that the culture medium can be accurately analyzed with dilution-only pretreatment. In addition, the results of CCV and internal standard recoveries showed good long-term stability.</p>
<h4><strong>4. Thermo Fisher Scientific: <a href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_002821_tea_icap_ms_icap_tqe_industrial_an002821_em_en_b60acdccc6.pdf">Analysis of process water from hydrogen fuel cells using triple quadrupole inductively coupled plasma mass spectrometry (ICP-MS)</a></strong></h4>
<ul>
<li>Application</li>
</ul>
<p><strong>Keywords:</strong> Fluorine, fuel cell, high resolution, ICP-MS, KED, PEM, process water, triple quadrupole, TQ-O2 mode</p>
<p><strong>Goal:</strong> To demonstrate the analysis of process water from hydrogen fuel cells for inorganic trace contaminants with high sensitivity and accuracy using triple quadrupole ICP-MS</p>
<p><strong>Conclusions:</strong> The iCAP TQe ICP-MS was employed to analyze 53 elements including fluorine in process water derived from hydrogen fuel cells. Among the analytes, several critical interferences can cause unexpected bias, and these were investigated closely for effective and complete removal by means of selective collision / reaction cell reactions with oxygen. This study also included the development of a method for the analysis of fluorine, generally only possible in an indirect measurement. This analytical method was rigorously tested, and the results obtained clearly demonstrate the fowling analytical advantages:</p>
<ul>
<li>The iCAP TQe ICP-MS operated in TQ-O2 and He KED modes allowed the analysis of 53 elements in relevant sample matrices over a wide concentration range. For minor elements, the method was tested over 4 orders of magnitude (from 0.01 to 100 µg·L-1), whereas major elements were tested between 1 to 100 µg·L⁻¹.</li>
<li>Using a high throughput analysis approach, with a new autosampler equipped with a Step Ahead feature for minimizing total analysis time, all elements relevant for the development of hydrogen fuel cell technology could be measured accurately with low detection limits.</li>
<li>The use of TQ-O₂ mode provided advanced performance for eliminating the polyatomic interferences of phosphorus, sulfur, silver, and cadmium in the simulated hydrogen fuel cell process water. This covered both polyatomic interferences as well as overlaps created by intense signals from isotopes of elements present in high concentrations.</li>
<li>he iCAP TQe ICP-MS offers the flexibility to choose high resolution for the Q1 and Q3 quadrupoles, enabling complete elimination of polyatomic interference and isobaric interferences.</li>
<li>The feasibility of fluorine analysis was demonstrated using an indirect method after complexation with barium. The iCAP TQe ICP-MS showed accurate and precise determination of fluorine as proven by the spike recovery tests performed.</li>
<li>Excellent stability performance was obtained with the iCAP TQe ICP-MS together with excellent CCV and spike recovery results over a 3-hour run without internal standard correction. This provides the advantage of avoiding potential contamination from addition of the internal standard solution.</li>
</ul>


News from LabRulezICPMS - Library Week 34, 2024

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in week 35, 2024? Check out new documents from the field of spectroscopy, especially ICP/MS techniques!</strong></p><blockquote><h4>👉 <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT ICPMS AND RELATED TECHNIQUES</strong></a></h4></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><strong>LabRulezGCMS</strong></a> libraries.</p></blockquote><p>This week we bring to you a poster from <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/events/568"><strong>ASMS 2024</strong></a> by <strong>Agilent Technologies</strong>, applications by <strong>Shimadzu</strong>, <strong>Thermo Fisher Scientific</strong>, and <strong>Metrohm</strong>!</p><h4><strong>1. Agilent Technologies: </strong><style type="text/css"></style><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/po_8900_esi_microfast_yeast_asms_2024_wp774_en_agilent_06b2ce4cfb.pdf"><strong>Elemental Analysis in Yeast Cells and Selenium Enriched Yeast Cells by ICP-MS with Automated Micro-Flow Sample Introduction</strong></a></h4><ul><li>poster / <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/companies/296"><strong>ASMS 2024</strong></a></li></ul><p><strong>Introduction: </strong>Nanoparticle and single cell elemental analysis by ICP-MS has become popular in recent years due technological advancements in ICP-MS, as well as increasing needs for many other advancing fields of applications (1). In the current study, an automated, micro-flow autosampler in combination with an Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) is used in the elemental analysis of nanoparticles and yeast cells. The sample introduction system is designed to deliver intact single cells or cell clusters to the plasma, while the ICP-MS offers high sensitivity for elemental determination within the cell or cell cluster. The preliminary results from this current study can potentially be applied to other applications, offering an easy and efficient way for high-throughput sample analysis.</p><p><strong>Conclusions:</strong> There is good agreement in the number of detected cells that contained the four elements, confirming the feasibility of the scICP-MS method for the measurement of multiple elements in single cells.</p><h4><strong>2. </strong><style type="text/css"></style><strong>Shimadzu: </strong><style type="text/css"></style><style type="text/css"></style><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_00718_en_8760c1a035.pdf"><strong>Screening Analysis of 24 Elemental Impurity Elements in Drugs Using ICPMS-2040/2050</strong></a></h4><ul><li>Application</li></ul><p><strong>User Benefits</strong></p><ul><li>Controlled elements can be verified by a screening analysis of 24 elemental impurity elements.&nbsp;</li><li>Use of the preset method in LabSolutions™ ICPMS makes it possible to begin the analysis simply without laborious study of conditions.</li><li>Study of candidate elements for internal standard correction is possible.</li></ul><p><strong>Introduction:</strong> The ICH Q3D Guideline for Elemental Impurities 1) establishes permitted daily exposure (PDE) levels for 24 elements of toxicological concern. The elementsthat should be considered in risk assessments differ, depending on the administration route of the drug product. For oral preparations, only seven elements of Class 1 and 2A should be considered, except for the intentional addition of elements such as catalyst utilization during synthesis. However, the origins of contamination by elemental impurities are diverse, including not only the components of the drug substance and additives, but also manufacturing equipment and implements. Therefore, a screening analysis was carried out for all 24 elements, considering potential elemental impurities. In addition, when internal standard correction is to be used, as in a related article a, the content of candidate internal standard elements in the specimens must be verified in advance. In this article, a simple concentration analysis of the 24 elements in a drug product as elemental impurities was carried out using the preset method for screening analysis of drug products, which is included in the ICPMS-2040/2050 (Fig. 1). The concentration of the elements used in internal standard correction in the drug was also measured, and it was found that the elements can be used in correction.</p><p><strong>Conclusion:</strong> In this article, a simultaneous screening analysis of 24 elemental impurity elements in an oral drug product and candidate elements for internal standard correction was carried out using an ICPMS-2040/2050. The time and work necessary in study and registration of the analysis conditions and measured masses of the large number of elements in this experiment can be greatly reduced by using the preset method of the LabSolutionsICPMS software.</p><h4><strong>3. </strong><style type="text/css"></style><style type="text/css"></style><strong>Thermo Fisher Scientific: </strong><style type="text/css"></style><style type="text/css"></style><style type="text/css"></style><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an41218_oe_basic_inclusion_analysis_en_024ffa9f51.pdf"><strong>Iron and steel - ARL iSpark Plus Optical Emission Spectrometer - Basic inclusion analysis</strong></a></h4><ul><li>Application</li></ul><p><strong>Benefits&nbsp;</strong></p><ul><li>Ultra-fast evaluation of some main inclusion types</li><li>Close to real-time inclusion check in up to hundreds of samples a day</li><li>More effective control of inclusiondependent steel properties</li><li>Helps reduce the number of costly issues caused by inclusions</li></ul><p><strong>Basic inclusion analysis</strong></p><p>Non-metallic inclusions dramatically affect steel properties and cause process issues like nozzle clogging. The costs associated with bad steel properties, process issues or customer complaints may amount to several hundred thousand dollars every year. Controlling the formation and the modification of non-metallic inclusions has therefore become essential to the production of modern steels as demanded by today’s markets.</p><p>The Thermo Scientific ARL iSpark Plus is a high-end metal analyzer that allows precise and accurate elemental analysis of steel. It also enables ultra-fast analysis of non-metallic inclusions, enabling a steel plant to control steel quality and production process even more effectively, and considerably reduce the costs associated with unwanted inclusions.</p><p>The Basic Inclusion Analysis Spark-DAT (Spark Data Analysis and Treatment) option is the entry-level method for standard inclusion analysis in low alloy steel. It reports the amounts of some of the most common types of non-metallic inclusions together with the elemental concentrations, helping steel plants to guarantee the quality and the properties of the steel product, as well as the smooth running of the production process.</p><p>Principles and details on Spark-DAT inclusion analysis can be found in the application note of the Standard Inclusion Analysis (AN41219).</p><h4><strong>4. </strong><style type="text/css"></style><style type="text/css"></style><style type="text/css"></style><strong>Metrohm: </strong><style type="text/css"></style><style type="text/css"></style><style type="text/css"></style><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_nir_118_download_7c2174fc54.pdf"><strong>Quantification of cotton content in textiles by near-infrared spectroscopy</strong></a></h4><ul><li>Application</li></ul><p><strong>Fast, non-destructive determination of cotton with NIRS</strong></p><p>Cotton and polyester are two of the most popular fabrics for creating garments. Polyester is a synthetic material produced from petrochemical products, and cotton is a natural and sustainable fiber harvested from cottonseeds. Polyester is the best choice for water-resistant, durable apparel, while cotton is better suited for breathable, cool summer clothing. Textile products must be labeled according to their fiber composition. The procedures for the determination of fiber composition include mechanical, chemical, and microscopic methods—all of which are time consuming. In contrast, nearinfrared spectroscopy (NIRS) is a fast and chemicalfree alternative. This Application Note shows how NIR spectroscopy can be used to determine the cotton content in textile products within 30 seconds.</p><p><strong>CONCLUSION</strong></p><p>&nbsp;This Application Note demonstrates the feasibility of NIR spectroscopy to determine the cotton percentage in textile blends quickly and easily. Vis-NIR spectroscopy offers users a fast, cost-effective, and highly accurate alternative to other standard testing methods.</p><p>Additionally, NIRS analysis is non-destructive, completely reagent-free, and gives results in only 30 seconds.</p>

News from LabRulezICPMS - Library Week 35, 2024

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 30th June 2025? Check out new documents from the field of spectroscopy/spectrometry and related techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><strong>LabRulezGCMS</strong></a> libraries.</p></blockquote><p>This week we bring you posters by <strong>Agilent Technologies / ASMS </strong>and<strong> Thermo Fisher Scientific / ASMS</strong>!</p><h3><strong>1. Agilent Technologies / ASMS: Measurement of Metals in Tissue Samples Using Laser Ablation-ICP-MS and an Organic Matrix-Based Standard</strong></h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/ps_8890_la_icp_ms_metals_tissue_asms_2025_thp_067_en_agilent_ee9bc7a285.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Laser Ablation-Inductively Coupled Plasma-Mass Spectroscopy (LA-ICP-MS) can provide localization information of elements on solid samples. Therefore, bioimaging techniques using LA-ICP-MS have been developed to investigate the distribution of metals on thin sections.&nbsp;</p><p>Primary biliary cholangitis (PBC) is an autoimmune disorder that primarily targets the interlobular bile ducts. The resulting bile duct damage causes chronic cholestasis in the liver, which can eventually progress to cirrhosis. It is well-established that individuals with PBC exhibit impaired copper (Cu) excretion, leading to Cu accumulation within the liver.&nbsp;</p><p>Pathologists have employed orcein or Victoria blue staining to visualize Cu deposition in pathological specimens. 1 Orcein staining is commonly used to assess the stage of PBC. However, both staining methods measure Cu levels indirectly by detecting Cu-binding proteins, which introduces significant variability in measurement accuracy across different facilities and yields relatively low detection sensitivity.&nbsp;</p><p>The aim of the study was to directly quantify Cu in PBC specimen using LA-ICP-MS, a highly sensitive technique, and compare the results with that obtained from normal-looking tissue in liver. The elemental concentrations were determined from external calibration curves generated using an organic matrix-based standard (Solid scaleTM, FUJIFILM Wako Chemicals).&nbsp;</p><h4><strong>Conclusions</strong></h4><p>This study demonstrates the high performance of the Agilent <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=8900+ICP-QQQ"><strong>8900 ICP-QQQ</strong></a> equipped with an ESL 213 laser ablation system for bioimaging human liver specimens.&nbsp;</p><ul><li>An organic matrix-based standard (Solid scaleTM ) provided quantitative results of metals in human liver specimens.&nbsp;</li><li>Patterns of metal distribution (24Mg, 31P, 44Ca, 56Fe, 63Cu, 95Mo) in human liver showed accumulation of Cu in a PBC specimen and its unique localization pattern along the regenerative nodule.&nbsp;</li></ul><p>These results demonstrate that determining metal concentrations in thin sections using LA-ICP-MS provides valuable insights into the mechanisms of PBC and other metal-related diseases.</p><h3><strong>2. Thermo Fisher Scientific / ASMS: Trace metals analysis in baby food using triple quadrupole inductively coupled plasma mass spectrometry (TQ-ICP-MS)</strong></h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/PO_296_ASMS_25_metals_baby_food_TQ_ICP_MS_na_en_3c869a51aa.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Many countries have established their own regulations and guidelines to ensure the safety and quality of baby food products. These regulations are generally based on scientific research and risk assessments conducted by health and food safety authorities. Among a range of other contaminants, toxic heavy metals, such as lead, arsenic, cadmium, and mercury, are subject to screening.&nbsp;</p><p>The Baby Food Safety Act of 2021 requires manufacturers and the FDA to take long overdue action by setting maximum levels of inorganic arsenic (10 μg∙kg-1, 15 μg∙kg-1 for cereal), lead (5 μg∙kg-1, 10 μg∙kg-1 for cereal), cadmium (5 μg∙kg-1, 10 μg∙kg-1 for cereal), and mercury (2 μg∙kg-1) allowed in baby food.&nbsp;</p><p>Since January 2022, baby food manufacturers need to meet these maximum levels for toxic elements by testing their final products (because only ingredient testing significantly underestimates toxic heavy metal levels in the final product), and to post the results of their product testing online twice per year. Similarly, as the FDA is working on a “closer to zero plan”, the European Union has established regulations and maximum limits for various contaminants, including toxic elements, in baby food. ICP-MS (inductively coupled plasma mass spectrometry) is the commonly used analytical technique to measure trace elements in various samples, including baby food. The specific trace elements to be checked by ICP-MS in baby food may vary depending on the purpose of the analysis and the specific concerns related to the safety and quality of the product.</p><h4><strong>Materials and methods&nbsp;</strong></h4><h5><strong>Instrumentation&nbsp;</strong></h5><p>A <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1488"><strong>Thermo Scientific iCAP MTX ICP-MS</strong></a> and a Thermo Scientific <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1715"><strong>iSC-65 Autosampler</strong></a> were used for analysis. The ICP-MS was operated using the parameters highlighted in Table 1. To facilitate the robustness to analyze a high number of potentially very different sample types, the instrument was operated using argon gas dilution (AGD), applying a mild (approximately 5 times) dilution to all samples. This ensures the productivity and uptime requirements in a high productivity laboratory environment can be met. To meet the stringent detection limit requirements put in place by regulatory authorities, the iCAP MTX ICP-MS was operated in SQ-KED and TQ-O2 modes to confidently eliminate all polyatomic and isobaric interferences but also deliver the sensitivity needed to reach the requested quantification limits for the critical elements.</p><h4><strong>Results&nbsp;</strong></h4><p>Table 3 summarizes the analytical figures of merit for all analytes including the correlation coefficients, the limits of quantification, and the quantification limits of the method (MLOQ). Whereas the limit of quantification (LOQ) only considers what can be quantified by the instrument, the method quantification limit (MLOQ) also accounts for the complete sample preparation, i.e., the sample weight and the dilution factor. Specifically highlighted in the table are the results obtained for As, Cd, Hg, and Pb, elements which are of specific regulatory concern due to their toxicity and risk for bioaccumulation. As can be seen, the achieved MLOQs are at least a factor two lower compared to the nominal limits specified in EAM 4.7.</p><h4><strong>Conclusions&nbsp;</strong></h4><p>This workflow, combining sample preparation using microwave assisted digestion and analysis using the iCAP MTX ICP-MS, allows accurate measurement of the concentration of toxic elements, dangerous for children, as well as the essential elements, necessary for the good growth and health of children, in various baby food products.&nbsp;</p><ul><li>The automatic and constant 5-times dilution allows robust analysis of different types of baby food products, whether dry, liquid, or fatty, without any compromise on sensitivity to reach the regulated limits.&nbsp;</li><li>The stability of the iCAP MTX ICP-MS allows a large variety of different food samples can be analyzed in the same run, ensuring productivity in an applied testing laboratory.&nbsp;</li><li>All types of interferences (polyatomic as well as isobaric interference, including doubly charged ions) are effectively suppressed with either helium collision gas or by using oxygen as a reactive gas in triple quadrupole mode.&nbsp;</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1489"><strong>Qtegra ISDS Software</strong></a> with the Reaction Finder functionality, allows simplified handling for the operator by automatically defining the isotopes and the acquisition modes to obtain reliable results.&nbsp;</li><li>The maintenance assistant also ensures alerts to the user when actions need to be carried out by the operator to guarantee an instrument with best performance throughout instrument lifetime.</li></ul>

News from LabRulezICPMS Library - Week 27, 2025

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 7th July 2025? Check out new documents from the field of spectroscopy/spectrometry and related techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><strong>LabRulezGCMS</strong></a> libraries.</p></blockquote><p>This week we bring you brochure by <strong>Anton Paar, </strong>poster by<strong> Shimadzu / ASMS </strong>and application note by<strong> Thermo Fisher Scientific</strong>!</p><h3><strong>1. Anton Paar: Dynamic Shear Rheometers for Asphalt SmartPave</strong></h3><ul><li>Brochure</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/C92_IP_013_EN_K_Brochure_Smart_Pave_screen_dda7b47acc.pdf"><strong>Full PDF for download</strong></a></li></ul><p>The <strong>SmartPave brochure</strong> introduces a family of dynamic shear rheometers (DSR) – <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=444&amp;search=SmartPave+92"><i><strong>SmartPave 92</strong></i></a>, <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=444&amp;search=SmartPave+102e"><i><strong>SmartPave 102e</strong></i></a>, and<a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=444&amp;search=+MCR+502e+Power"><strong> </strong><i><strong>MCR 502e Power</strong></i></a> – specifically developed for the demanding rheological characterization of asphalt binders and bitumen. These instruments meet international standards such as AASHTO, ASTM, DIN EN, and others, and support a wide temperature range, enabling tests for routine quality control, research, and advanced performance grading.</p><p>Each SmartPave system is equipped with innovative features like EC motors for high-precision torque control, <strong>Toolmaster™</strong> for automatic tool recognition, and <strong>TruRay™</strong> sample illumination. The Peltier-based temperature control – with heating from both above and below – ensures fast, accurate, and stable temperature conditions without water circulation. This allows fully dry operation, which is particularly important for repeatable and noise-free measurements.</p><p>The brochure outlines various standard and advanced testing methods, such as <strong>Superpave PG grading (AASHTO T315)</strong>, <strong>MSCR tests (AASHTO T350)</strong>, <strong>viscosity measurements (ASTM D4402)</strong>, and <strong>GTR-modified asphalt analysis</strong>. Advanced applications include DMA on solid asphalt, master curves, and low-temperature measurements down to –160 °C. The modular system supports multiple geometries including parallel-plate, cone-plate, and concentric-cylinder setups.</p><p>All systems operate with the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=444&amp;search=RheoCompass+software"><strong>RheoCompass® software</strong></a>, offering intuitive test design, automated calibration, standard operating procedures (SOPs), and customizable analysis. This makes SmartPave systems ideal for both routine lab use and advanced asphalt R&amp;D, offering unmatched performance, ease of use, and compliance with global asphalt testing standards.</p><h3><strong>2. Shimadzu / ASMS: Arsenic Speciation in Rice and Rice Products using LC-ICP-MS: A Sensitive and Reliable Approach by Shimadzu&nbsp;</strong></h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/ASMS_2025_THP_065_99cfe0ebbb.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Arsenic toxicity is a major public health concern, particularly in drinking water, leading to strict regulatory limits worldwide. While total arsenic has traditionally been measured, its toxicity largely depends on its chemical form with inorganic species Arsenite and Arsenate (As(III) and As(V)) being highly toxic and carcinogenic, and organic forms monosodium methyl arsenate (MMA) and disodium methyl arsenate (DMA) displayed in fig. 1, considered less harmful. Speciation analysis is therefore essential for accurate risk assessment.&nbsp;</p><p>Rice and rice-based products are of particular concern, as rice can efficiently accumulate inorganic arsenic from the environment. In response, the European Union established maximum residue levels (MRLs) for inorganic arsenic in rice under Commission Regulation (EU) 2015/1006, highlighting the need for precise speciation.&nbsp;</p><p>To address this, advanced techniques like liquid chromatography coupled with inductively coupled plasma mass spectrometry (LC-ICPMS) are employed. LC-ICPMS provides high sensitivity and specificity for arsenic species determination, ensuring regulatory compliance and protecting consumer health.&nbsp;</p><p>This study presents the effective use of Shimadzu’s <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=1&amp;search=LC-ICPMS-2050+LF"><strong>LC-ICPMS-2050 LF</strong></a> system for arsenic speciation in rice and related products.</p><h4><strong>Methods and Materials</strong></h4><p>All standard stock solutions are prepared as specified in the LC-ICP-MS Method Package for Arsenic Speciation Analysis Type-2 by Shimadzu, Japan. Seven levels of mixed calibration standards are prepared and injected for the quantification of arsenic species. Calibration curves are generated using the external standard calibration method with a 1/l weighted regression. All samples are prepared in duplicate to verify method performance. Additionally, two spiked samples containing only inorganic arsenic standards are included to evaluate the extraction efficiency of the method.&nbsp;</p><p>The Shimadzu <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=1&amp;search=ICPMS-2050+LF"><strong>ICPMS-2050 LF</strong></a>, coupled with the Nexera LC series (Fig. 2), manufactured by Shimadzu Corporation, Japan, is used to separate and quantify the different arsenic species present in the samples.</p><h4><strong>Conclusion&nbsp;</strong></h4><ul><li>The extraction procedure employed effectively ensures the recovery of inorganic and organic arsenic species from various sample types, including both raw and processed materials.&nbsp;</li><li>A highly sensitive method based on hyphenated techniques, specifically LC-ICPMS, is developed for the speciation and quantification of arsenic using the Shimadzu ICPMS-2050 LF coupled with a Nexera inert LC system.</li></ul><h3><strong>3. Thermo Fisher Scientific: EDXRF analysis of coal fly ash as loose powders Ling Yok Ung, Application Specialist</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/edxrf_analysis_of_coal_fly_ash_as_loose_powders_an41971_en_2960bf7ad9.pdf"><strong>Full PDF for download</strong></a></li></ul><p>All the waste that remains after coal is burned, often in a coalfired power station, is referred to as coal ash. Coal ash may contain lead, mercury, arsenic and many other heavy metals. Fly ash and bottom ash are two subcategories of coal ash, typically separated based on particle size.&nbsp;</p><p>More than half of coal leftovers are fly ash, the most abundant and well-known component. Particles of fly ash, the lightest type of coal ash, “fly” up into a power plant’s exhaust stacks because they are so light. About 99 % of the ash are captured by filters inside the stacks, which draw it in with opposing electrical charges. Fly ash can be recycled. The fine particles are a perfect material for wallboard and concrete because they bond together and solidify, especially when combined with water.&nbsp;</p><p>But fly ash from coal is also a dangerous industrial solid waste. The natural environment and human health are seriously threatened by its excessive worldwide production, inappropriate disposal methods, underutilization, and lack of knowledge about its inherent risks. Therefore, a method that is quick, precise, and accurate, is required to quantify coal fly ash. Many companies use X-ray fluorescence spectrometry (XRF) as a preferred technology for process and quality control since it is a proven analytical approach that can accurately assess the chemical composition of materials with limited sample preparation.</p><h4><strong>Instrumentation&nbsp;</strong></h4><p>The <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1209"><strong>Thermo Scientific™ ARL™ QUANT’X EDXRF Spectrometer</strong></a> is equipped with a Silicon Drift Detector (SDD) and a 50 Watt Rh or Ag target X-ray tube which is air cooled with a maximum excitation v The Thermo Scientific™ ARL QUANT’X™ EDXRF Spectrometer is equipped with the following features: and radiation of heat in our atmosphere; N2 and O2 which are present in much higher concentrations do not have this same characteristic effect. Atmospheric CO2 levels increase the temperature of the surface of our planet, simultaneously excess CO2 is dissolved into the oceans gradually lowering the water’s pH, thus making the seas more acidic.&nbsp;</p><ul><li>Silicon drift detector (SDD): The SDD remains the performance benchmark for all energy dispersive detectors. The large active area of 30 mm² enables effective capture of characteristic element X-rays emitted by the sample.&nbsp;</li><li>50 W Rh or Ag target X-ray tube: Air-cooled with a maximum excitation voltage of 50 kV.&nbsp;</li><li>Nine primary beam filters: Designed to optimize the peak-to-background signals for all elements from F to Am.&nbsp;</li><li>10-Position auto-sampler with spinner: Allows for unattended analysis of multiple samples.</li></ul><h4><strong>Conclusion&nbsp;</strong></h4><p>This application note shows the suitability of the ARL QUANT’X EDXRF Spectrometer for the analysis of coal fly ash samples. This compact instrument allows for reliable and fast analysis of coal fly ash. Accuracy and repeatability results show that satisfactory results are obtainable for an analysis of loose powder in vacuum. This is a significant advantage for simple sample preparation while providing good accuracy &amp; precision.</p>

News from LabRulezICPMS Library - Week 28, 2025

<p><strong>From September to December 2025, ICP/MS and atomic spectrometry experts will have many opportunities to meet worldwide. The global program includes key conferences, symposia, and workshops covering elemental analysis, chemical speciation, sample preparation, and emerging analytical methods. These events bring together researchers, instrument developers, and industry professionals to exchange knowledge, present innovations, and strengthen collaborations across borders.</strong></p><h3><strong>Upcoming ICPMS Conferences, Schools, Courses and Workshops in 2025</strong></h3><h5><strong>14th International Conference on Instrumental Methods of Analysis (IMA-2025)</strong></h5><ul><li>14–17 September 2025 | Kefalonia, Greece</li><li><strong>Organizer:</strong> National Technical University of Athens</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/events/795">More information and registration at this link</a></li></ul><h5><strong>53rd Conference on Synthesis and Analysis of Drugs 2025</strong></h5><ul><li>17–19 September 2025 | Kurdějov, Czech Republic</li><li><strong>Organizer: </strong>Masaryk University</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/events/678">More information and registration at this link</a></li></ul><h5><strong>21th ISC ‘Modern Analytical Chemistry’</strong></h5><ul><li>18–19 September 2025 | Prague, Czech Republic</li><li><strong>Organizer: </strong>European Chemical Society (EuChemS)</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/events/839">More information and registration at this link</a></li></ul><h5><strong>MSACL 2025 – 15th Annual Conference &amp; Exhibits</strong></h5><ul><li>21–26 September 2025 | Montréal, Canada</li><li><strong>Organizer:</strong> MSACL</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/events/731">More information and registration at this link</a></li></ul><h5><strong>7th International Mass Spectrometry School (IMSS) 2025</strong></h5><ul><li>21–26 September 2025 | Vorau, Styria, Austria</li><li><strong>Organizer:</strong> International Mass Spectrometry Foundation</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/events/906">More information and registration at this link</a></li></ul><h5><strong>GDCh Science Forum Chemistry 2025</strong></h5><ul><li>29 September – 1 October 2025 | Karlsruhe, Germany</li><li><strong>Organizer:</strong> Gesellschaft Deutscher Chemiker (GDCh)</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/events/755">More information and registration at this link</a></li></ul><h5><strong>International Symposium on Preparative and Process Chromatography (PREP) 2025</strong></h5><ul><li>29 September – 2 October 2025 | Philadelphia, PA, USA</li><li><strong>Organizer: </strong>LD Organisation srl</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/events/899">More information and registration at this link</a></li></ul><h5><strong>21st Raman Imaging Symposium</strong></h5><ul><li>29 September – 1 October 2025 | Ulm, Germany</li><li><strong>Organizer: </strong>Oxford Instruments</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/events/898">More information and registration at this link</a></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/21st_Raman_Imaging_Symposium_13c3033654.jpg" alt="Oxford Instruments: 21st Raman Imaging Symposium" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_21st_Raman_Imaging_Symposium_13c3033654.jpg 245w," sizes="100vw" width="1200" height="627"></p><h5><strong>SciX 2025</strong></h5><ul><li>5–10 October 2025 | Covington, KY, USA</li><li><strong>Organizer</strong>: The Federation of Analytical Chemistry and Spectroscopy Societies (FACSS)</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/events/796">More information and registration at this link</a></li></ul><h5><strong>Gulf Coast Conference (GCC) 2025</strong></h5><ul><li>14–15 October 2025 | Galveston, Texas, USA</li><li><strong>Organizer: </strong>Gulf Coast Conference</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/events/905">More information and registration at this link</a></li></ul><h5><strong>SOFT 2025</strong></h5><ul><li>26–31 October 2025 | Portland, OR, USA</li><li><strong>Organizer: </strong>Society of Forensic Toxicologists</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/events/767">More information and registration at this link</a></li></ul><h5><strong>ASMS – 36th Fall Workshop</strong></h5><ul><li>3–4 November 2025 | Seattle, WA, USA</li><li><strong>Organizer</strong>: ASMS</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/events/746">More information and registration at this link</a></li></ul><h5><strong>The International Doctoral Conference on Advances in Chemistry (IDCAC 2025)</strong></h5><ul><li>7–8 November 2025 | University of Chemistry and Technology, Prague</li><li><strong>Organizer: </strong>UCT Prague</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/events/911">More information and registration at this link</a></li></ul><h5><strong>8th Brazilian Meeting on Chemical Speciation &amp; 17th Rio Symposium on Atomic Spectrometry</strong></h5><ul><li>9–14 November 2025 | São Pedro, Brazil</li><li><strong>Organizer: São Paulo State University (UNESP)</strong></li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/events/867">More information and registration at this link</a></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/8th_Espe_Q_Brasil_and_17th_RSAS_cover_image_3d033251e3.jpg" alt="8th EspeQBrasil &amp; 17th RSAS" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_8th_Espe_Q_Brasil_and_17th_RSAS_cover_image_3d033251e3.jpg 245w," sizes="100vw" width="1601" height="898"></p><h5><strong>AAPS 2025 PHARMSCI 360</strong></h5><ul><li>9–12 November 2025 | San Antonio, TX, USA</li><li><strong>Organizer: </strong>AAPS</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/events/753">More information and registration at this link</a></li></ul><h5><strong>24th Human Proteome Organization World Congress (HUPO) 2025</strong></h5><ul><li>9–13 November 2025 | Toronto, Canada</li><li><strong>Organizer: </strong>HUPO</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/events/732">More information and registration at this link</a></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/HUPO_2025_24th_Human_Proteome_Organization_World_Congress_cover_image_jpg_1256bb4d21.jpg" alt="HUPO 2025: 24th Human Proteome Organization World Congress (HUPO) 2025" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_HUPO_2025_24th_Human_Proteome_Organization_World_Congress_cover_image_jpg_1256bb4d21.jpg 245w," sizes="100vw" width="1280" height="720"></p><h5><strong>SETAC North America 46th Annual Meeting</strong></h5><ul><li>16–20 November 2025 | Portland, Oregon, USA</li><li><strong>Organizer:</strong> SETAC</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/events/754">More information and registration at this link</a></li></ul><h5><strong>Eastern Analytical Symposium (EAS) 2025</strong></h5><ul><li>17–19 November 2025 | Plainsboro, NJ, USA</li><li><strong>Organizer: </strong>Eastern Analytical Symposium and Exposition</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/events/902">More information and registration at this link</a></li></ul><h5><strong>TIAFT 2025</strong></h5><ul><li>23–27 November 2025 | Auckland, New Zealand</li><li><strong>Organizer: </strong>The International Association of Forensic Toxicologists</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/events/768">More information and registration at this link</a></li></ul><h5><strong>Sample Preparation Seminar</strong></h5><ul><li>2–3 December 2025 | Online</li><li><strong>Organizer:</strong> Phenomenex</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/events/742">More information and registration at this link</a></li></ul>

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