News from LabRulezICPMS - Library Week 35, 2024
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Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in week 35, 2024? Check out new documents from the field of spectroscopy, especially ICP/MS techniques!
👉 SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT ICPMS AND RELATED TECHNIQUES
👉 Need info about different analytical techniques? Peek into LabRulezLCMS or LabRulezGCMS libraries.
This week we bring to you a poster from ASMS 2024 by Agilent Technologies, applications by Shimadzu, Thermo Fisher Scientific, and Metrohm!
1. Agilent Technologies: Elemental Analysis in Yeast Cells and Selenium Enriched Yeast Cells by ICP-MS with Automated Micro-Flow Sample Introduction
- poster / ASMS 2024
Introduction: Nanoparticle and single cell elemental analysis by ICP-MS has become popular in recent years due technological advancements in ICP-MS, as well as increasing needs for many other advancing fields of applications (1). In the current study, an automated, micro-flow autosampler in combination with an Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) is used in the elemental analysis of nanoparticles and yeast cells. The sample introduction system is designed to deliver intact single cells or cell clusters to the plasma, while the ICP-MS offers high sensitivity for elemental determination within the cell or cell cluster. The preliminary results from this current study can potentially be applied to other applications, offering an easy and efficient way for high-throughput sample analysis.
Conclusions: There is good agreement in the number of detected cells that contained the four elements, confirming the feasibility of the scICP-MS method for the measurement of multiple elements in single cells.
2. Shimadzu: Screening Analysis of 24 Elemental Impurity Elements in Drugs Using ICPMS-2040/2050
- Application
User Benefits
- Controlled elements can be verified by a screening analysis of 24 elemental impurity elements.
- Use of the preset method in LabSolutions™ ICPMS makes it possible to begin the analysis simply without laborious study of conditions.
- Study of candidate elements for internal standard correction is possible.
Introduction: The ICH Q3D Guideline for Elemental Impurities 1) establishes permitted daily exposure (PDE) levels for 24 elements of toxicological concern. The elementsthat should be considered in risk assessments differ, depending on the administration route of the drug product. For oral preparations, only seven elements of Class 1 and 2A should be considered, except for the intentional addition of elements such as catalyst utilization during synthesis. However, the origins of contamination by elemental impurities are diverse, including not only the components of the drug substance and additives, but also manufacturing equipment and implements. Therefore, a screening analysis was carried out for all 24 elements, considering potential elemental impurities. In addition, when internal standard correction is to be used, as in a related article a, the content of candidate internal standard elements in the specimens must be verified in advance. In this article, a simple concentration analysis of the 24 elements in a drug product as elemental impurities was carried out using the preset method for screening analysis of drug products, which is included in the ICPMS-2040/2050 (Fig. 1). The concentration of the elements used in internal standard correction in the drug was also measured, and it was found that the elements can be used in correction.
Conclusion: In this article, a simultaneous screening analysis of 24 elemental impurity elements in an oral drug product and candidate elements for internal standard correction was carried out using an ICPMS-2040/2050. The time and work necessary in study and registration of the analysis conditions and measured masses of the large number of elements in this experiment can be greatly reduced by using the preset method of the LabSolutionsICPMS software.
3. Thermo Fisher Scientific: Iron and steel - ARL iSpark Plus Optical Emission Spectrometer - Basic inclusion analysis
- Application
Benefits
- Ultra-fast evaluation of some main inclusion types
- Close to real-time inclusion check in up to hundreds of samples a day
- More effective control of inclusiondependent steel properties
- Helps reduce the number of costly issues caused by inclusions
Basic inclusion analysis
Non-metallic inclusions dramatically affect steel properties and cause process issues like nozzle clogging. The costs associated with bad steel properties, process issues or customer complaints may amount to several hundred thousand dollars every year. Controlling the formation and the modification of non-metallic inclusions has therefore become essential to the production of modern steels as demanded by today’s markets.
The Thermo Scientific ARL iSpark Plus is a high-end metal analyzer that allows precise and accurate elemental analysis of steel. It also enables ultra-fast analysis of non-metallic inclusions, enabling a steel plant to control steel quality and production process even more effectively, and considerably reduce the costs associated with unwanted inclusions.
The Basic Inclusion Analysis Spark-DAT (Spark Data Analysis and Treatment) option is the entry-level method for standard inclusion analysis in low alloy steel. It reports the amounts of some of the most common types of non-metallic inclusions together with the elemental concentrations, helping steel plants to guarantee the quality and the properties of the steel product, as well as the smooth running of the production process.
Principles and details on Spark-DAT inclusion analysis can be found in the application note of the Standard Inclusion Analysis (AN41219).
4. Metrohm: Quantification of cotton content in textiles by near-infrared spectroscopy
- Application
Fast, non-destructive determination of cotton with NIRS
Cotton and polyester are two of the most popular fabrics for creating garments. Polyester is a synthetic material produced from petrochemical products, and cotton is a natural and sustainable fiber harvested from cottonseeds. Polyester is the best choice for water-resistant, durable apparel, while cotton is better suited for breathable, cool summer clothing. Textile products must be labeled according to their fiber composition. The procedures for the determination of fiber composition include mechanical, chemical, and microscopic methods—all of which are time consuming. In contrast, nearinfrared spectroscopy (NIRS) is a fast and chemicalfree alternative. This Application Note shows how NIR spectroscopy can be used to determine the cotton content in textile products within 30 seconds.
CONCLUSION
This Application Note demonstrates the feasibility of NIR spectroscopy to determine the cotton percentage in textile blends quickly and easily. Vis-NIR spectroscopy offers users a fast, cost-effective, and highly accurate alternative to other standard testing methods.
Additionally, NIRS analysis is non-destructive, completely reagent-free, and gives results in only 30 seconds.
