<div><div>Researchers led by <a target="_blank" rel="noopener noreferrer" href="https://kudova.group.uochb.cz/en">Eva Kudová</a> from IOCB Prague and Jitka Viktorová from UCT Prague have identified new androstane-based steroid derivatives that can significantly improve the effectiveness of existing antibiotics against multidrug-resistant Staphylococcus aureus.</div></div><div>The team screened dozens of natural steroidal hormones and synthetic derivatives to see whether they could block bacterial efflux pumps – mechanisms that bacteria use to eject antibiotics and survive treatment. Two compounds emerged as particularly promising: they inhibited efflux pumps and lowered the effective doses of antibiotics such as ciprofloxacin and erythromycin.Further analysis showed that one of the compounds also suppressed genes linked to bacterial virulence. Another key finding is that the most active molecules are non-toxic to human immune cells and showed no detectable endocrine activity, suggesting a favorable safety profile.These findings support the idea that rationally designed steroid-based molecules could act as antibiotic adjuvants, helping existing drugs overcome bacterial resistance.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/IOCB_Prague_Steroidal_hormones_and_neurosteroids_novel_therapeutic_strategies_in_bacterial_infections_8e5d2a7b48.jpg" alt="IOCB Prague: Steroidal hormones and neurosteroids – novel therapeutic strategies in bacterial infections" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_IOCB_Prague_Steroidal_hormones_and_neurosteroids_novel_therapeutic_strategies_in_bacterial_infections_8e5d2a7b48.jpg 222w," sizes="100vw" width="1258" height="886"><blockquote><h4>Original Article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S0223523426001613?via%3Dihub">Steroidal hormones and neurosteroids - novel therapeutic strategies in bacterial infections: Design, synthesis, and biological evaluation</a></h4>Daniela Brdová, Bára Křížkovská, Jan Špaček, Zdeněk Míchal, Eva Jablonská, Ondřej Strnad, Hana Chodounská, Eszter Szánti-Pintér, Marina Morozovová, Václav Hanžl, Jan Tkadlec, Martijn Riool, Jan Lipov, Jitka Viktorová, Eva Kudová&nbsp;Eur. J. Med. Chem., 2026, 308, 118716<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1016/j.ejmech.2026.118716">https://doi.org/10.1016/j.ejmech.2026.118716</a><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote><h4>Abstract</h4>The global rise of antibiotic resistance necessitates novel therapeutic strategies for infectious diseases. Inhibition of bacterial efflux pumps, which contribute to multidrug resistance, represents a promising approach to restore or even increase the efficacy of existing antibiotics. Using fluorescence-based ethidium bromide accumulation, broth microdilution, and checkerboard assays, we evaluated 26 endogenous steroidal hormones and neurosteroids, along with 30 synthetic derivatives, for their ability to enhance antibiotic susceptibility in multidrug-resistant Staphylococcus aureus. Structure-activity relationship analysis identified compounds 13 and 16 as lead candidates, exhibiting strong efflux pump inhibition and marked reductions in the minimum inhibitory concentrations of ciprofloxacin and erythromycin. Both compounds showed additive effects in checkerboard assays. Modifications at C-3 (polar substitution) and C-17 (3α,5β-stereochemistry and nonpolar substitution) were essential for potent efflux inhibition and sensitization, although these modifications were not additive when combined. Transcriptome analysis further revealed that compound 13 significantly downregulated S. aureus virulence-associated genes when administered alone or in combination with antibiotics. Cytotoxicity assessment in human peripheral blood mononuclear cells and receptor transactivation assays for estrogen, androgen, and progesterone receptors indicated that the most active derivatives were non-toxic and lacked detectable endocrine activity, suggesting a favorable safety profile. Overall, these findings support the concept that rationally designed andostane-based steroidal scaffolds can function as competitive bacterial efflux pump inhibitors and serve as potential antibiotic adjuvants to mitigate efflux-mediated resistance.<h4>Instrumentation</h4><h5>Structural characterization</h5><ul><li>AVANCE III 400 MHz NMR spectrometer (Bruker)</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?mainauthorItems=3&amp;search=LTQ+Orbitrap+XL">LTQ Orbitrap XL HRMS</a> (Thermo Fisher Scientific, ESI)</li></ul></div>

Steroidal hormones and neurosteroids – novel therapeutic strategies in bacterial infections

Wiley, a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation and learning, today announced the release of additional data to its IR and Raman spectral libraries, significantly broadening compound coverage, including materials, polymers, minerals, and others.This latest release includes the first installment of Raman spectra from Wiley's collaboration with the American Museum of Natural History (AMNH), announced earlier this spring, drawing from one of the world's most important mineral collections.“Researchers depend on reference data as a foundation for sound scientific decisions,” said Graeme Whitley, senior director, data science solutions at Wiley. “Continuous updates ensure scientists always have the most current, reliable reference libraries at their fingertips, helping them work faster and make confident decisions when it matters most.”<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_Wiley_expands_its_trusted_IR_and_Raman_spectral_library_collections_helping_analytical_labs_make_faster_more_confident_decisions_1a54aaad3a.jpg" alt="Wiley: Wiley expands its trusted IR and Raman spectral library collections—helping analytical labs make faster, more confident decisions" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Wiley_Wiley_expands_its_trusted_IR_and_Raman_spectral_library_collections_helping_analytical_labs_make_faster_more_confident_decisions_1a54aaad3a.jpg 245w," sizes="100vw" width="1600" height="856"><h4>Summary of updates:</h4><h5>KnowItAll Raman Spectral Library Collection</h5><ul><li>Added: 1,213 spectra</li><li>Now contains: 29K+ spectra</li></ul>2 new databases:<ul><li>Raman – American Museum of Natural History Minerals – Wiley – 198 spectra</li><li>Raman – Microbiology – 71 spectra</li></ul>Spectra added to databases:<ul><li>Raman – Consumer Goods &amp; Food-Related Compounds – +104</li><li>Raman – Drugs – +128</li><li>Raman – Materials – +132</li><li>Raman – Minerals – +233</li><li>Raman – Polymers – +5</li><li>Raman – Pigments &amp; Dyes – +342</li></ul><h5>KnowItAll IR Spectral Library Collection</h5><ul><li>Added: 949 spectra</li><li>Now contains: 344K+ spectra</li></ul>7 new databases:<ul><li>ATR-IR – Clinical – 364 spectra</li><li>ATR-IR – Materials – 10 spectra</li><li>ATR-IR – Pigments &amp; Dyes – 420 spectra</li><li>ATR-IR – Polymers – 21 spectra</li><li>IR – Clinical – 20 spectra</li><li>IR – Materials – 17 spectra</li><li>IR – Microbiology – 75 spectra</li></ul>Spectra added to databases:<ul><li>IR – Minerals – +5</li><li>IR – Polymers – +17</li></ul>Spectral library subscribers automatically gain access to new data, ensuring labs always have the most current, reliable reference libraries to improve analysis, reduce errors, and increase productivity.<ul><li>Learn more at: <a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/spectral-databases/">www.sciencesolutions.wiley.com/spectral-databases</a></li><li>Existing subscribers can access step-by-step guidance on updating their KnowItAll databases at <a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/how-to-update-knowitall-databases">https://sciencesolutions.wiley.com/how-to-update-knowitall-databases</a></li></ul><h5>Wiley Spectral Databases</h5>Wiley's spectral databases are consistently evolving to meet today's research demands, covering multiple spectral techniques across a wide range of applications including polymers, materials, environmental, forensics, toxicology, pharmaceutical, biotech, automotive, aerospace, food, cosmetics, and more. Built on rigorous quality protocols, Wiley delivers industry-leading spectral data and intelligent tools to accelerate analysis and deliver deeper insights — making it the authoritative, trusted source that analytical labs worldwide rely on.&nbsp;<h5>About Wiley</h5>Wiley (NYSE: WLY) is a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation, and learning. With more than 200 years at the center of the scholarly ecosystem, Wiley combines trusted publishing heritage with AI-powered platforms to transform how knowledge is discovered, accessed, and applied. From individual researchers and students to Fortune 500 R&amp;D teams, Wiley enables the transformation of scientific breakthroughs into real-world impact. From knowledge to impact—Wiley is redefining what's possible in science and learning.&nbsp;

Wiley expands its trusted IR and Raman spectral library collections

Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 4th May 2026? Check out new documents from the field of spectroscopy/spectrometry and related techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">LabRulezGCMS</a> libraries.</blockquote>This week we bring you application notes by KNAUER, Shimadzu, and Thermo Fisher Scientific!<h3>1. KNAUER: Analysis of HPLC fractions by Benchtop NMR</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/knauer_hplc_benchtop_nmr_web_638c60e13c.pdf">Full PDF for download</a></li></ul>Preparative HPLC is essential for isolating compounds and removing impurities in pharmaceutical and chemical industries. Non-destructive, fast analysis is preferred to maintain yield and enable at-line monitoring, avoiding lengthy sample preparation. Recent advancements in benchtop NMR spectrometers (up to 90 MHz) allow quick analysis without deuterated solvents. In this proof-of-concept study we purified a pharmaceutical sample via HPLC and confirmed its identity using benchtop NMR. Fractions (0.7–4.4 mM) were analyzed without preparation, using only 300 µL per sample, ensuring rapid batch control with no product loss. This study demonstrates the seamless integration of HPLC and benchtop NMR.<h4>Experimental</h4><h5>Preparative HPLC Method</h5>Eluent 20:80 Ethanol/water, isocratic mode, flow rate 12.5 ml/min, detection UV254 nm 2 Hz, 500 µl stacked injection, automated fractionation with threshold function, column temperature ambient, Column Eurospher II 100-10 C18 150x20 mm&nbsp;<h5>Analytical HPLC Method</h5>Eluent 20:80 Ethanol /water + 0.1% formic acid, isocratic mode, flow rate 1 ml/min, detection UV254 nm 10 Hz, 5 µl partial loop injection, column temperature 25 °C, Column <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1633">Eurospher II 100-5 C18</a> 150x4 mm&nbsp;<h5>NMR Method&nbsp;</h5>NMR spectra were acquired on a Magritek Multi-X Ultra 80 MHz benchtop NMR system using an adapted WET sequence for solvent suppression. 32 scans were acquired with a repetition time of 15s. WET parameters were adjusted for each sample to yield optimal suppression for all solvent signals. Pooled HPLC fractions were analysed directly without addition of deuterated solvents or other sample preparation.<h4>Conclusion</h4>This proof-of-concept study successfully shows that HPLC and benchtop NMR can be used together easily. Samples can be analyzed non-destructively within minutes and without any further preparation due to highly efficient suppression of multiple solvent signals. Compounds can be identified without the need of reference standards. This study shows that NMR can provide a valid compatible alternative detector for HPLC fraction analysis.<h3>2. Shimadzu: DIC Analysis in High-Speed Tensile Test of CFRP</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_00854_en_fb6c68b858.pdf">Full PDF for download</a></li></ul><h4>User Benefits</h4><ul><li>The <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=1&amp;search=HPV-X3">HPV-X3</a> is suitable for observation of fracture of brittle materials such as CFRP because it has a maximum recording speed (framerate) of 20 Mfps.&nbsp;</li><li>The HPV-X3 provides improved DIC analysis performance, as its resolution is 3 times higher than that of the conventional highspeed video camera.</li><li>The HITS-TX impact testing machine enables testing at a maximum speed of 20 m/s</li></ul>Carbon fiber reinforced plastic (CFRP) is a material with particularly high specific strength, even among composite materials, and used in various applications such as transport aircraft, taking advantage of its excellent mechanical properties. Because CFRP consists of carbon fibers and resin, it shows complex fracture behavior, and brittle fracture progresses from damage as the point of origin. Since fracture proceeds instantaneously, a high-speed video camera with a high recording speed is necessary when observing fracture of CFRP. One method for measuring strain in a high-speed tensile test is Digital Image Correlation (DIC), which visualizes the distribution of strain at the specimen surface by comparing a random pattern on the specimen surface before and after deformation. Thus, a high-speed video camera with a high resolution is also necessary in order to improve the DIC performance.&nbsp;Newly-developed <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=1&amp;search=HPV-X3">Hyper Vision HPV-X3 high-speed video camera</a> is extremely well-suited to DIC analysis of CFRP, as its recording speed is 2 timesfaster and itsresolution is 3 times higher than the conventional HPV-X2. In this experiment, a high-speed tensile test of CFRP was conducted using a HITS-TX high-speed tensile testing machine. The condition of the test was observed with the new HPV-X3, and the strain distribution of the CFRP test piece was clarified by a DIC analysis of the recorded images.<h4>Test Piece and Test Instruments</h4>A CFRP quasi-isotropic laminate was used as the test piece. Aluminum foil was glued to the back side of the test piece, and the timing when the electrical conduction of the aluminum foil was interrupted by fracture of the test piece was used as the trigger for video recording. The HITS-TX was used in the highspeed tensile test. The HPV-X3 was used in fracture observation, and for comparison, the fracture process was also recorded with the conventional HPV-X2 camera. Fig. 1 shows the condition of the test, and Table 1 and Table 2 show the equipment composition and test conditions, respectively.<h4>DIC Analysis Results in High-Speed Tensile Test</h4>Fig. 3 shows the DIC analysis results in the high-speed tensile test. The color bar was set to display the color purple at around 0 % strain and red at around 2 % strain. Fig. 3 (1) is an image at the start of the test. After the test started, strain in the 45˚ direction concentrated from the lower left to the right central area, as can be seen in Fig. 3 (2). Then, as the test progressed, a condition of increasing strain in the initial area of strain concentration can be seen in Fig. 3 (3) to (9). A crack occurs in Fig. 3 (10), and strain decreases in the crack area. Following this, the test piece fractured completely in Fig. 3 (11) and (12), and a decrease in the strain in the area around the crack could be observed.<h4>Conclusion</h4>A high-speed tensile test of CFRP was conducted using a HITSTX high-speed tensile testing machine and the newlydeveloped HPV-X3 high-speed video camera, and the strain distribution at the time of test piece fracture was visualized by a DIC analysis. Because the HPV-X3 offers a 3 times higher resolution and a 2 times faster recording speed than the conventional device, it is a suitable high-speed video camera for fracture observation and DIC analysis in impact tests of brittle materials such as CFRP. The measurement system introduced in this Application News article is a useful tool for the development of composite materials.<h3>3. Thermo Fisher Scientific: Polymer analysis using femtosecond-laser-ablation depth profiling</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/xps_depth_profiling_polymer_analysis_appnote_c731e2e7e0.pdf">Full PDF for download</a></li></ul>X-ray photoelectron spectroscopy (XPS) is an essential polymer characterization technique that can identify not just the elemental composition but also the chemical state of polymer samples. This allows the chemical bonding environment to be deduced and, as a result, the polymer species can be identified. This can all be achieved with minimal sample preparation thanks to the built-in charge-compensation systems found in XPS instruments, which simplify the analysis of insulating samples.&nbsp;The introduction of gas cluster ion sources (GCIS), such as the Thermo Scientific™ MAGCIS Dual Mode Ion Source, marked a major step forward in polymer analysis. Unlike monatomic ion beams, GCIS are able to clean surface contamination, and etch away layers of sample material, without damaging the underlying chemistry of organic samples such as polymers. As a result, GCIS has allowed chemical-damage-free analysis to reach micrometers below the sample surface. This depth of analysis can be highly time consuming, however, and total experimental times can range from multiple hours to days.&nbsp;The addition of femtosecond-laser-ablation (fs-LA) technology is alleviating this, allowing for XPS spectra to be collected from a depth of tens of µm into a sample in a matter of minutes. This is because the laser ablation occurs on the femtosecond timescale (i.e., nearly instantaneously), effectively eliminating the material removal time of the depth profile. Additionally, unlike other material removal techniques such as atomic ion beam impact (where a collision cascade effect is induced to remove surface material) fs-LA is capable of removing material without chemical damage due to the ultrashort columbic explosion process used to eject the material. The resulting profile is therefore representative of the actual sample chemistry.<h4>Paint layer analysis&nbsp;</h4>In traditional ion-beam depth profiling, analytical depths are generally limited to several hundred nanometers, up to a micrometer. This means that it is extremely difficult to analyze the interfaces between multiple micrometer-thick layers in a sample without the use of additional techniques such as ultralow-angle microtome (ULAM) sectioning.¹ The introduction of fs-LA technology, however, allows micrometers of material to be removed rapidly, enabling the characterization of layered samples.&nbsp;As an example, a multi-layer paint specimen (provided by the University of Surrey, UK) was depth profiled using the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2206">Thermo Scientific™ Hypulse™ Surface Analysis System</a>. The sample consists of an aluminum substrate coated with a 5 µm layer of polyurethane primer followed by a 25 µm PMMA/PVdF topcoat.The depth profile was generated using a 1,030 nm laser with an energy of 250 µJ for ablation, along with a 30 µm X-ray spot size for data collection. XPS spectra were collected after each ablation cycle to obtain an atomic concentration plot through both paint layers into the substrate material (Figure 2).&nbsp;5 distinct regions throughout the analyzed depth can be seen. The top surface of the sample consists of an adventitious layer of carbon contamination, which is commonly found on samples exposed to air. The second layer is the 25 µm PVdF/PMMA topcoat, and the third layer is the PU primer. Between the primer and the final aluminum substrate layer, a clear increase in adventitious carbon is observed, similar to the signal seen at the top sample surface. This suggests residual carbon contamination was present on the substrate before the paint layers were applied.&nbsp;It would take hours to produce the XPS depth profile shown in Figure 2 using traditional ion beam approaches. Even with the use of a monatomic beam with a high energy per atom, the length of the analysis could still be just as long, depending on the sample material, and would sacrifice the chemistry of any organic/polymeric materials. The combination of fs-LA depth profiling and snapshot XPS acquisition, meanwhile, can reduce the experimental time to less than 20 minutes without inducing any chemical damage to the sample surface.<h4>Summary&nbsp;</h4>One of the most critical aspects of successful polymer XPS depth profiling is the preservation of the sample chemistry during material removal. Additionally, experiment time can be a significant limiting factor, and thicker samples could lead to reduced time for repeat experiments. The femtosecond laser ablation capabilities of the Hypulse Surface Analysis System provide fast, efficient, and chemical-damage-free material removal from a sample surface, enabling analysis multiple micrometers into a sample. This means that hidden sample interfaces, that were largely inaccessible before, can now be analyzed easily and efficiently

News from LabRulezICPMS Library - Week 19, 2026

Article

Product

Application

Video

Science and research

Software

The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) is a leading scientific institution in the Czech Republic, recognized internationally. Its primary mission is basic research in the fields of chemical biology and medicinal chemistry, organic and material oriented chemistry, chemistry of natural compounds, biochemistry and molecular biology, physical chemistry, theoretical chemistry, and analytical chemistry. 

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

For over 200 years we have been helping people and organizations develop the skills and knowledge they need to succeed.
We develop digital education, learning, assessment, and certification solutions to help universities, businesses, and individuals move between education and employment and achieve their ambitions.

Wiley

New Food magazine

SPECTRO Analytical Instruments

Bruker

C&EN

Shimadzu Corporation

Metal detection or X-ray inspection – which is right for food safety?
Join this webinar to learn about each technology, their its respective capabilities and limitations and discover where and why on your line either may be the preferred choice and why..
Metal detection and X-ray inspection are frequently deployed at different points of the production process to help ensure food safety and quality. It is not uncommon to find both technologies on a product line at different points of the process. This webinar will provide comparative information about these foreign object detection technologies and their respective capabilities, helping to inform what may be most appropriate for your individual product, packaging and processing requirements.
Key learning points:
<ul>
<li>Learn about each technology, their respective capabilities and limitations
</li>
<li>Discover where and why on your line either may be the preferred choice for each technology
</li>
<li>Explore options from general-purpose to highly specialised.
</li>
</ul>
<blockquote>
Presenter: Kim DurkotKim Durkot (Field Marketing Manager, Product Inspection)
</blockquote>
<blockquote>
Kim joined Thermo Fisher Scientific in November 2021 as Field Marketing Manager for the Product Inspection business. Kim brings experience in both upstream and downstream marketing. In her previous role as Product Marketing Manager, she collaborated closely with customers to ensure key market requirements were clearly defined and validated to Engineering throughout the product development process. Kim has a BS in Marketing from Eastern Illinois University and an MBA from the Olivet Nazarene University.
</blockquote>

New Food: Metal detection or X-ray inspection: which is right for your application?

Metal detection or X-ray inspection: which is right for your application?

Learn about each technology, their its respective capabilities and limitations.

Metal detection or X-ray inspection

X-ray Absorption Spectroscopy (XAS) is a powerful and versatile technique that fits into the larger landscape of material characterization techniques by providing unique, element-specific insights into the local atomic structure, electronic properties, and bonding interactions of materials.
It complements and enhances the information obtained from other characterization methods, contributing to a more comprehensive understanding of materials. 
In this session, we will discuss the utility of XAS and how newly developed lab-scale instrumentation enables its practical use as an everyday tool for materials characterization. Come see real world applications of laboratory XAS. 
Key Learning Objectives:
<ul>
<li>Introduction to X-ray Absorption Spectroscopy and its unique capabilities for materials characterization.
</li>
<li>Detailed look into example applications of laboratory XAS. 
</li>
<li>Overview of new lab-scale XAS instrumentation.
</li>
<li>Understanding the process of conducting a laboratory XAS measurement, including a real-time measurement demonstration.
</li>
</ul>
Who Should Attend:
<ul>
<li>Research Scientists from Universities or Industries that routinely perform materials characterization.
</li>
<li>Materials Characterization Lab Managers and Users interested in understanding new techniques.
</li>
<li>Those interested in element-specific, non-destructive material analysis.
</li>
</ul>
<blockquote>
Presenter: Dr. Devon Mortensen (CEO, easyXAFS)
</blockquote>
<blockquote>
Presenter: Dr. William Holden (CTO, easyXAFS)
</blockquote>
<blockquote>
Presenter: Dr. Zachary Lebens-Higgins (Testing and R&amp;D Manager, easyXAFS)
</blockquote>
<blockquote>
Presenter: Catherine Dold (Health &amp; Environment Writer, C&amp;EN Media Group)
</blockquote>

C&EN: Lab X-ray Absorption: A New Dimension for Materials Characterization

Lab X-ray Absorption: A New Dimension for Materials Characterization

The utility of XAS and how newly developed lab-scale instrumentation enables its practical use as an everyday tool for materials characterization.

Lab X-ray Absorption for Materials Characterization

X-ray Photoelectron Spectroscopy (XPS) is a powerful tool used for characterizing materials and analyzing surfaces, playing a significant role in developing materials for the green energy sector.
Join us for an informative session on Shimadzu’s Digital Classrooms to explore how XPS contributes to innovation solutions towards sustainability.
Herein, discover valuable insights that XPS offers into the chemical composition and surface properties of materials used in next-generation solar cell materials and advanced battery components. XPS, a non-destructive technique, offers highly precise and detailed information about the elemental composition and chemical states of these material surfaces.
Our session will also showcase the capabilities of the AXIS Supra+ photoelectron spectrometer. Get to experience first-hand how XPS enhances our understanding of surface chemistry and electronic structure, leading to optimization in material performance, efficiency, and durability.
As we find ourselves in an era of growing environmental concerns, XPS plays a crucial role in the development of sustainable energy technologies. Join us as we explore how XPS enables scientists and engineers to create a cleaner, greener future for the next generations to come.
Learning Objectives:
<ul>
<li>Importance of surface analysis for green energy sector materials
</li>
<li>Applications of XPS
</li>
<li>Importance of high sensitivity &amp; high energry resolution XPS
</li>
<li>Capabilities of AXIS Supra+
</li>
</ul>
<blockquote>
Presenter: Dr. Adam Roberts (Marketing Manager, Kratos Analytical Ltd)
</blockquote>
<blockquote>
Dr. Roberts joined Kratos Analytical as an Applications Specialist in the Surface Analysis business in 1998. With over 25 years of experience in applications of surface analysis for materials characterization Adam has great depth of knowledge of the subject. This scientific experience has been developed in parallel with commercial sales and marketing of the scientific instruments supplied by Kratos Analytical.
</blockquote>
<blockquote>
Presenter: Dr. Simon Hutton (Sales Manager, Kratos Analytical Ltd)
</blockquote>
<blockquote>
Dr. Hutton is currently Sales Manager for surface analysis products at Kratos Analytical. He started as an applications specialist and still has a &#39;hands-on&#39; approach to instrument sales, acquiring applications data when time allows. Simon has many years experience of XPS and surface analysis.
</blockquote>
<blockquote>
Presenter: Tan Teck Beng (Product Manager (Scientific), Shimadzu (Asia Pacific))
</blockquote>
<blockquote>
Tan Teck Beng is the Product Manager for Scientific Instrument in Shimadzu Asia Pacific. He has been providing application support for OES, XRF, XRD, EPMA, SPM and ESCA for the past 20 years. He has conducted numerous Application Seminars and Workshops on Materials Characterization/Failure Analysis/Restriction of Hazardous Substances in countries supported by Shimadzu Asia Pacific. The countries where he has conducted include Malaysia, Indonesia, Thailand, India, Philippines, Myanmar, Vietnam and Singapore. He is currently providing Application and Technical Support for Shimadzu Scientific Instruments for more than 200 companies in Asia Pacific Region utilizing shimadzu scientific instruments. He has an MSc degree in Materials Science from the National University of Singapore.
</blockquote>

Shimadzu: X-ray Photoelectron Spectroscopy: Powering the Future of Renewable Energy

X-ray Photoelectron Spectroscopy: Powering the Future of Renewable Energy

Explore how XPS contributes to innovation solutions towards sustainability.

X-ray Photoelectron Spectroscopy: Renewable Energy

AA or ICP-OES/MS is often viewed as the golden standard to analyze elements during the pharmaceutical manufacturing process, from drug discovery to the QA/QC of final formulations.
While extremely accurate, these techniques have the downside of requiring the sample to be in liquid form when analyzing, resulting in a very arduous sample-preparation process and long analysis time.
In this seminar, we would introduce Energy-Dispersive X-Ray Fluoroscopy (EDX) as an alternative technique to perform elemental analysis that requires little sample preparation, is easy to use and can provide results quickly; and how it could be used in various areas of the pharmaceutical industry.
Learning Objectives:
<ul>
<li>Understanding how EDX can be used to perform elemental analysis
</li>
<li>Understanding how EDX can be used in the Pharma Industry
</li>
<li>Advantages of using EDX for elemental analysis
</li>
</ul>
<blockquote>
Presenter: Tan Teck Beng (Senior Product Specialist, Shimadzu (Asia Pacific) Pte. Ltd.)
</blockquote>
<blockquote>
Tan Teck Beng has been providing application support for XRF, XRD, EPMA, SPM and ESCA for the past 19 years in Shimadzu (Asia Pacific). He has conducted numerous Application Seminars and Workshops on Materials Characterization/Failure Analysis/Restriction of Hazardous Substances in many countries in the region, including Malaysia, Indonesia, Thailand, India, Philippines, Myanmar, Vietnam and Singapore.
</blockquote>
<blockquote>
He is currently providing Application and Technical Support for Shimadzu&#39;s Scientific Instruments for more than 200 companies in Asia Pacific Region.
</blockquote>
<blockquote>
Presenter: Mizuno Motohisa (Deputy General Manager, Scientific Sales, Shimadzu (Asia Pacific) Pte. Ltd.)
</blockquote>
<blockquote>
Mizuno-san has worked for Sales for the past 20 years in Shimadzu Japan. He has worked at Shimadzu’s Tokyo and Kyushu and Kansai branch offices and has extensive experience in catering to customers belonging to pharma, academia, food and chemical, among others. Before moving to Shimadzu (Asia Pacific), he served as a Sales Manager in the Kansai branch for the past 3 years, where he was in-charge of pharma customers as part of the Analytical &amp; Measuring Instruments Division.
</blockquote>

Shimadzu: EDX: A Fast & Simple Technique for Pharmaceutical Elemental Analysis

EDX: A Fast & Simple Technique for Pharmaceutical Elemental Analysis

Energy-Dispersive X-Ray Fluoroscopy (EDX) as an alternative technique to perform elemental analysis that requires little sample preparation.

EDX: A Fast & Simple Technique

Complying with the European Union (EU) or India&#39;s directive on Restriction of Hazardous Substances (RoHS) is an ongoing challenge for many companies.
Too often, their compliance activities are unnecessarily complicated by a lack of understanding about what the regulation requires, and how to stay compliant when new restricted substances are introduced. Here in this webinar, our expert team will try to explain about the latest regulation, its implications, along with easy testing solutions to stay compliant to avoid any enforcement action.
Learning Objectives:
<ul>
<li>Basic introduction &amp; history of RoHS
</li>
<li>Latest update on RoHS, RoHS2 regulation
</li>
<li>RoHS : Indian Scenario
</li>
<li>Solutions : Various testing methods
</li>
</ul>
<blockquote>
Presenter: Abhinandan Sharma (Asst. Manager - Sales, Shimadzu Analytical India Pvt Ltd)
</blockquote>
<blockquote>
Mr. Abhinandan Sharma has more than 15 years long experience of technical sales of analytical instruments and currently he is working for Shimadzu Analytical India Pvt Ltd since 2013 and looking after ED-XRF business for last 7 years.
</blockquote>
<blockquote>
Presenter: Pravin Tyagi (Manager - Sales, Shimadzu Analytical India Pvt Ltd)
</blockquote>
<blockquote>
Mr Pravin Tyagi is currently working as sales manager at Shimadzu Analytical India Pvt Ltd &amp; heading Indian business of scientific instrument division which includes EDX, XPS, EPMA, OES. He has been associated with Shimadzu since 2009 &amp; keep on organizing various application oriented seminars/workshops specifically designed to cater the requirement of various industries/institutes.
</blockquote>

Shimadzu: RoHS : Regulatory compliance and it's solutions

RoHS : Regulatory compliance and it's solutions

The latest regulation, its implications, along with easy testing solutions to stay compliant to avoid any enforcement action.

Over the past few decades, the widespread utility and applicability of X-ray photoelectron spectroscopy (XPS) in research and development has made it the most popular and widely used technique of surface analysis.
Our latest generation spectrometer, the AXIS Supra+, combines market leading spectroscopic and imaging capabilities with automation to ensure high sample throughput and ease of use. State-of-the-art performance including fast, high spatial resolution XPS imaging reveals the lateral distribution of surface chemistry and aids further characterisation with selected area analysis. We demonstrate the capabilities of the AXIS Supra+ and the technique of XPS in answering materials characterisation questions in application areas such as thin-films, biomaterials and Li-ion batteries.
Learning Objectives:
<ul>
<li>Understand the basic principles of XPS Instrumentation
</li>
<li>Achieve a total peace of mind for user through the highest level of automation
</li>
<li>Understand importance of high sensitivity &amp; high energy resolution XPS
</li>
<li>Explore new opportunities by high spatial resolution parallel imaging
</li>
</ul>
<blockquote>
Presenter: Simon Hutton (Ph.D.) (Sales Manager, Kratos Analytical Ltd)
</blockquote>
<blockquote>
Dr. Hutton is currently Sales Manager for surface analysis products at Kratos Analytical. He started as an applications specialist and still has a &#39;hands-on&#39; approach to instrument sales, acquiring applications data when time allows. Simon has many years experience of XPS and surface analysis.
</blockquote>
<blockquote>
 Presenter: Adam Roberts (Ph.D.) (Marketing Manager, Kratos Analytical Lt)
</blockquote>
<blockquote>
Dr. Roberts joined Kratos Analytical as an Applications Specialist in the Surface Analysis business in 1998. With over 20 years of experience in applications of surface analysis for materials characterisation Adam has great depth of knowledge of the subject. This scientific experience has been developed in parallel with commercial sales and marketing of the scientific instruments supplied by Kratos Analytical.
</blockquote>

Shimadzu: X-Ray Photoelectron Spectroscopy Technology

X-Ray Photoelectron Spectroscopy Technology

Understand the basic principles of XPS Instrumentation.

As we all know, the need for efficient and sustainable energy storage solutions has never been greater. With the increasing demand for electric vehicles, and storage of renewable energy, the battery industry together with academic institutes are constantly evolving and pushing the boundaries of what is possible.Bruker is at the forefront of this innovation, providing cutting-edge technologies and solutions for battery research and manufacturing. In this webinar, we will explore the latest developments in Bruker's technology and how they can be applied to optimize battery performance, reduce costs, and accelerate the path towards a cleaner energy future.Join our 75 minutes experts discussion as they dive into the fascinating world of batteries and discover how Bruker is shaping the future of it.Key Learning Topics:<ul><li>You will learn about a complete portfolio of technologies applied to battery research and production, including AFM, NMR, EPR, MS, FTIR, XRD, XRF, XRM, RAMAN, EDS and EBSD. These technologies represent the excellence of Bruker's analytical tools and are complementary in their applications. They are used in various ways to help researchers and manufacturers understand how batteries work, how they can be improved, and how they can be produced and recycled more efficiently.</li></ul>Who Should Attend?<ul><li>Battery manufacturers</li><li>Research and development organizations</li><li>Academic institutions</li><li>Material science organizations</li><li>Electrochemical and analytical chemistry organizations</li><li>Testing laboratories involved in battery research and development.</li><li>Government agencies involved in renewable energy and sustainability.</li><li>Investors interested in the battery market.</li><li>Battery technology experts and engineers</li></ul><blockquote>Presenter: Andrea Steck Ph.D. (Principal Scientist - Bruker BioSpin (Ettlingen, Germany))Andrea Steck joined BBIO Germany in 2010 to perform contract services, then stepped into food profiling development, acted as Quality Manager (ISO-17025), and now is responsible for supporting, developing, and driving AIC-DEV projects as Principal Scientist.Andrea holds a PhD in Chemistry (TU Munich). She gained extensive experience in NMR pulse sequence development and structure elucidation (Berne, Switzerland), and in leading an analytical (NMR/MS/IR) laboratory in big pharmaceutical industry (Vienna, Austria). She then joined Bruker Austria as Manager Pursuant to Trade Law, responsible for contract services and customer acquisition.Presenter: Hugues Guérault (Application Manager – Bruker Advanced X-Ray Solutions (Karlsruhe, Germany))Hugues Guérault joined Bruker in 2002 as Application Scientist. He is now leading Bruker AXS application team and manages worldwide the activities of the application laboratories for equipment demonstrations and customer training.Hugues holds a PhD in Material Science from Le Mans University (France) and made a post-doc at the University of Leuven (Belgium). Overall, he has acquired more than 25 years of experience in material characterization using X-ray diffraction.Presenter: Peter De Wolf, PhD (Sr. Director AFM Technology Development &amp; Applications, Bruker Nano Surfaces &amp; Metrology, Santa Barbara, CA, USA)Joined Bruker after obtaining Ph.D. in Electrical Engineering from the University Leuven &amp; IMEC, Belgium in 1998 focused on the development of novel AFM characterization methods. Author and co-author of over 40 publications related to property characterization using AFM, and co-inventor of several AFM methods. In his role, Peter is responsible for developing, driving, and leveraging new technology and applications for Bruker’s AFM Instrumentation.Presenter: Ph.D. Bob Galvin, FRSC (Vice President BAMS, Bruker Daltonics, London, UK)Bob Galvin obtained his PhD using mass spectrometry to investigate novel catalytic reactions and since then has always been involved in this technology. &nbsp;He joined Bruker eleven years ago and has held a number of executive positions during this period.Presenter: Rebecca Keller (Scientific Content Creator – Bruker Scientific LLC (Billerica, MA, USA))Rebecca joined Bruker Scientific in 2022 to support scientific content creation for applied markets as well as research and academia. Thanks to her extensive experience in crafting content for chemistry e-learning platforms, she excels at presenting complex ideas with exceptional clarity and precision.Rebecca graduated in Chemistry at the University of Oregon in 2019 and has since sought to improve scientific communication by producing content across multiple platforms.Presenter: Michele Gironda (Head of Global Segment Management – Bruker Nano Analytics (Berlin, Germany))Michele Gironda joined Bruker in 2017 when Bruker acquired XGLab where he was Director Sales and Marketing. He is now our Head of Global Market Segment Management in the Nano Analytics Division. In his role Michele manages worldwide activities for the key strategic market segments in cooperation with sales, marketing, application and product managers.Michele holds a Master Degree in Engineering obtained with his studies in Politecnico di Milano (Italy) and Universitat Politecnica de la Catalunya in Barcelona (Spain).</blockquote>

Bruker: Shaping the future of batteries: Bruker technologies across the entire value chain

Shaping the future of batteries: Bruker technologies across the entire value chain

Join our 75 minutes experts discussion as they dive into the fascinating world of batteries and discover how Bruker is shaping the future of it.

Bruker technologies - Shaping future of batteries

<a target="_blank" rel="noopener noreferrer" href="https://www.spectro.com/xrf-principle">Energy-dispersive X-ray fluorescence (ED-XRF) technology</a>&nbsp;is transforming elemental analysis in the <a target="_blank" rel="noopener noreferrer" href="https://www.spectro.com/industries/miningandgeochem">mining sector</a>. It provides a rapid and reliable method for analyzing exploration samples, ores, feed materials, concentrates, and tailings, covering concentration ranges from percent to parts per million (ppm).Key advantages of ED-XRF include:<ul><li>Fast analysis time: Delivers results quickly, optimizing workflow efficiency</li><li>Cost-effectiveness: Low operating costs compared to alternative technologies</li><li>Ease of use: User-friendly interfaces reduce the need for extensive training</li><li>Stable calibrations: Long-term calibration stability ensures consistent and accurate results</li></ul>This webinar will showcase how <a target="_blank" rel="noopener noreferrer" href="https://www.spectro.com/products/xrf-spectrometer">advanced ED-XRF analyzers</a>&nbsp;can tackle common analytical challenges in mining, offering solutions that improve precision and operational efficiency.Attendees will gain insights into:<ul><li>Best practices for selecting the most suitable sample prep depending on the analytical goal</li><li>Innovations in ED-XRF technology that improve analytical performance</li><li>Application examples from graphite to rare earth ores/concentrates covering relevant elements from sodium to uranium</li></ul>

SPECTRO Analytical Instruments: Elemental Analysis in Mining With Advanced ED-XRF Technology

Elemental Analysis in Mining With Advanced ED-XRF Technology 

This webinar shows how advanced ED-XRF analyzers solve common mining challenges, improving analytical precision and boosting operational efficiency.

Elemental Analysis in Mining With Advanced ED-XRF Technology

This on-demand webinar presents an in-depth analysis of vanadium electrolytes using <a target="_blank" rel="noopener noreferrer" href="https://www.spectro.com/icp-oes-principle">ICP-OES</a>&nbsp;and <a target="_blank" rel="noopener noreferrer" href="https://www.spectro.com/xrf-principle">ED-XRF</a>&nbsp;technology. The analysis is essential for the optimization and quality control of vanadium redox flow batteries (VRFBs), which are recognized for their scalability, long lifespan, and high energy storage capacity. As VRFBs are increasingly integrated into renewable energy systems, ensuring the purity and chemical stability of vanadium electrolytes becomes critical for maintaining performance and extending battery life.The <a target="_blank" rel="noopener noreferrer" href="https://www.spectro.com/products/icp-oes-aes-spectrometers/arcos-inductively-coupled-plasma">SPECTRO ARCOS ICP-OES</a>, equipped with DSOI, delivers enhanced sensitivity and precision, making it particularly effective in detecting trace elements that may affect electrolyte performance. The webinar will outline the instrument’s capacity to meet current quality standards and its potential for future adaptability. The precision offered by the SPECTRO ARCOS ensures that even minor impurities are detected, thus facilitating better control over the electrolyte formulation and enhancing the efficiency of VRFBs in renewable energy applications.The <a target="_blank" rel="noopener noreferrer" href="https://www.spectro.com/products/xrf-spectrometer/xepos-xrf-spectrometer">SPECTRO XEPOS ED-XRF</a>&nbsp;analyzer delivers high sensitivity and flexibility, enabling accurate multi-elemental analysis of vanadium electrolytes, from trace to major components. With detailed experimental data on electrolyte samples at various states, the webinar will highlight how ED-XRF technology can identify and quantify impurities that could impact the efficiency and lifespan of VRFBs.

SPECTRO Analytical Instruments: Elemental Analysis of Vanadium Electrolytes Using ICP-OES and ED-XRF Technology

Elemental Analysis of Vanadium Electrolytes Using ICP-OES and ED-XRF Technology 

This on-demand webinar presents an in-depth analysis of vanadium electrolytes using ICP-OES and ED-XRF technology.

Vanadium Electrolyte Analysis with ICP-OES & ED-XRF

Watch this on-demand webinar to explore the amazing capabilities of the new <a target="_blank" rel="noopener noreferrer" href="https://www.spectro.com/products/handheld-xrf-analyzer">SPECTRO xSORT handheld XRF analyzer</a>. Discover the benefits of this advanced handheld XRF analyzer for these applications:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.spectro.com/industries/miningandgeochem">Mining</a>: Achieve quick and accurate analysis of ores, concentrates, and tailings, even in remote locations.</li><li><a target="_blank" rel="noopener noreferrer" href="https://www.spectro.com/industries/environmental">Environmental Testing</a>: Efficiently screen soil, sediment, waste, and other materials for heavy metals and toxic elements.</li><li>Compliance Screening: Ensure adherence to national and international regulations by detecting harmful substances in consumer goods and manufactured products.</li></ul>Gain first-hand insights into the analytical performance and benefits of combining handheld XRF with the powerful XRF Analyzer Pro software. Designed for all-day single-hand use, the SPECTRO xSORT offers a balanced, size-optimized, comfortable experience with an easy-read display and quick action software powered by Android. Experience the convenience of everywhere data and documentation with GPS, cameras, WiFi, Bluetooth, USB, and microSD capabilities. Transform your handheld device into a mini-lab system when mounted in the docking station.

SPECTRO Analytical Instruments: Advanced Handheld XRF Solutions for Mining, Environmental, and Compliance Applications 

Advanced Handheld XRF Solutions for Mining, Environmental, and Compliance Applications 

Explore the SPECTRO xSORT handheld XRF for fast, accurate mining, environmental, and compliance testing with advanced software and portability.

ICPMS webinars focusing on X-ray - page 9

X-ray Photoelectron Spectroscopy: Powering the Future of Renewable Energy

Lab X-ray Absorption: A New Dimension for Materials Characterization

Metal detection or X-ray inspection: which is right for your application?

Shaping the future of batteries: Bruker technologies across the entire value chain

X-Ray Photoelectron Spectroscopy Technology

RoHS : Regulatory compliance and it's solutions

EDX: A Fast & Simple Technique for Pharmaceutical Elemental Analysis

Advanced Handheld XRF Solutions for Mining, Environmental, and Compliance Applications

Elemental Analysis of Vanadium Electrolytes Using ICP-OES and ED-XRF Technology

Elemental Analysis in Mining With Advanced ED-XRF Technology

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