<p><strong>In the week from June 29, the following webinars await you in the field of atomic and molecular spectroscopy and spectrometry</strong></p><blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4><p><strong>👉 Search and filter in the largest global database</strong> with over <strong>5 500 GC, LC, MS and spectroscopy webinars</strong>.</p></blockquote><h5><strong>1. Metrohm: Simplifying Through-Container Testing with Raman Spectroscopy in the Pharmaceutical Industry</strong></h5><ul><li>Mo, 29.6.2026 15:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6308">Registration</a></li></ul><p>In this webinar, we will demonstrate a more robust and practical alternative to SORS for see-through Raman analysis.</p><h5><strong>2. SelectScience: End-to-end PAT: Connecting advanced analytics and data across the bioprocess lifecycle</strong></h5><ul><li>Mo, 29.6.2026 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6307">Registration</a></li></ul><p>Learn how integrated PAT strategies combining NMR, Raman, IR, and digital workflows enable continuous process understanding, smoother tech transfer, and QbD from development to GMP manufacturing.</p><h5><strong>3. Bruker: Bruker Fluorescence Microscopy Solutions: Automated Imaging and Light-Sheet Microscopy</strong></h5><ul><li>Tu, 30.6.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6309">Registration</a></li></ul><p>Discover Bruker’s integrated imaging ecosystem combining light-sheet microscopy, high-content screening, and high-performance data management for scalable, high-quality biological imaging workflows.</p><h5><strong>4. Agilent Technologies: Measuring Diverse Samples with UV/VIS Spectrometers and Integrating Spheres</strong></h5><ul><li>Tu, 30.6.2026 20:30 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6052">Registration</a></li></ul><p>This webinar will discuss diffuse transmission and reflection UV/VIS measurements, including how to perform measurements with Agilent’s Cary 60 UV/VIS Spectrometer.</p><h5><strong>5. Milestone: Unlock Smarter Digestion: AI and the Smart Features that Transform Your Daily Routine</strong></h5><ul><li>We, 1.7.2026 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6312">Registration</a></li></ul><p>Learn how Milestone’s intelligent digestion technologies, including MAIA AI Agent, easyTEMP, and SRC, help reduce downtime, simplify workflows, and improve laboratory productivity.</p><h5><strong>6. Bruker: High-Energy XRD - Diffraction Without Limits</strong></h5><ul><li>Th, 2.7.2026 10:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6314">Registration</a></li></ul><p>Join us to explore how high-energy XRD with the D8 ADVANCE HE and D8 DISCOVER HE enables the study of materials under realistic conditions.</p><h5><strong>7. Agilent Technologies: Spectral Flow Cytometry Masterclass - Session 1</strong></h5><ul><li>Fr, 3.7.2026 07:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6316">Registration</a></li></ul><p>Learn how full-spectrum flow cytometry enables high-dimensional cell analysis. Explore spectral flow technology, experimental design, and applications in immunology, oncology, and vaccine research.</p>

Webinars LabRulezICPMS Week 27/2026

<p><strong>The international standard ISO/IEC 17025 [1] clause 7.7.2 with regards to ensuring the validity of results, requires a laboratory to participate in proficiency testing (PT) and/or to participate in interlaboratory comparisons (ILCs) other than PT. However, no guidance as to what these other ILCs might be, or indeed how they might compare in relation to PT, is provided. This leaflet aims to outline other ILCs available, pointing out some of the limitations as compared to PT.&nbsp;</strong></p><p>There are three major types of ILCs in which a group of laboratories analyses identical portions from a homogeneous, stable test sample, with each type being characterized by its intended purpose [2,3]:</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Interlaboratory_comparisons_other_than_proficiency_testing_2_d9263807fb.jpg" alt="Eurachem: Interlaboratory comparisons other than proficiency testing" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Interlaboratory_comparisons_other_than_proficiency_testing_2_d9263807fb.jpg 245w," sizes="100vw" width="1507" height="607"></p><p>A key point is that PT is an ILC that is designed to specifically evaluate the performance of participants, providing them with an infrastructure to monitor and assess the validity of their results. This is not the key purpose of the two other ILCs, and thus depending on their intended purpose they have a number of limitations that laboratories need to be aware of when using them rather than PT. Only proficiency testing should have been conducted in full compliance to the competency standard ISO/IEC 17043 [4].&nbsp;</p><h4><strong>Evaluation of measurement procedure performance&nbsp;</strong></h4><p>These ILCs, are designed to assess how a particular measurement procedure performs and whether it is fit for its intended purpose. These ILCs are often referred to as a ‘method performance study’ or a ‘collaborative study’ [2]. Some limitations of using such ILCs for monitoring laboratory performance as an alternative to PT are:&nbsp;</p><ul><li>All participants use the same measurement procedure i.e. the measurement procedure that is being validated. Unless the measurement procedure is being routinely used by the participating laboratory such an ILC will not assess the routine performance of the laboratory using their own routine measurement procedure. Nor does it enable them to compare their performance with other laboratories using alternative measurement procedures.&nbsp;</li><li>The measurement procedure is likely to be new, so participants may not have established stable procedures and quality control, so performance may not reflect routine use.&nbsp;</li><li>The report from such an ILC would not provide information on the performance of the participant, if the statistical model used makes the assumption that all laboratories perform with equal variability.</li><li>The design of the study may require the participants to assess multiple samples and/or to undertake multiple replicate analysis on the test materials. This may not be representative of the routine measurements or tests undertaken by the laboratory.&nbsp;</li><li>The conclusion of the ILC might be that the measurement procedure being assessed is not valid.&nbsp;</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Interlaboratory_comparisons_other_than_proficiency_testing_3_a53ecd2f5d.jpg" alt="Eurachem: Interlaboratory comparisons other than proficiency testing" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Interlaboratory_comparisons_other_than_proficiency_testing_3_a53ecd2f5d.jpg 157w," sizes="100vw" width="570" height="566"></p><h4><strong>Characterisation of candidate reference materials&nbsp;</strong></h4><p>These are ILCs that assign a property value to a candidate reference material, usually with a stated measurement uncertainty. These are often referred to as a ‘material certification study’ [2]. Limitations of using such ILCs as an alternative to PT are:&nbsp;</p><ul><li>The analysis of the candidate reference material is likely to require additional care in exercising the routine measurement procedure, such as substantially more replication, and/or may require quite different reporting formats (e.g. all valid replicates instead of a mean result). Thus, such an ILC will not necessarily provide an evaluation of the performance of the laboratory based on the routine use of their measurement procedures.&nbsp;</li><li>The report from such an ILC may include the results from the participating laboratories but would not provide information on the performance of each laboratory.&nbsp;</li><li>Participating laboratories may be required to assess multiple samples and/or to undertake multiple replicate analysis on the candidate reference materials. Thus this may not be representative of the routine measurements or tests undertaken by the laboratory.&nbsp;</li></ul><h4><strong>Other ILCs&nbsp;</strong></h4><p>Some other ILCs, whilst not being conducted in full compliance of the requirements of ISO/IEC 17043, may be designed to evaluate participant performance. These would include small ILCs as defined by EA‑2/21 [5] or split sample ILCs i.e. where a portion of a single sample is sent to two or three laboratories. Whilst these ILCs are specifically designed to evaluate participant performance, they may not provide a comprehensive comparison that a PT might provide. In such cases the laboratory needs to evaluate carefully the competence of the organization managing the ILC and the suitability of the service externally provided (ISO/IEC 17025 clause 6.6).</p>

Interlaboratory comparisons other than proficiency testing

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 29th June 2026? Check out new documents from the field of spectroscopy/spectrometry and related techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><strong>LabRulezGCMS</strong></a> libraries.</p></blockquote><p>This week we bring you application notes by <strong>Agilent Technologies </strong>and<strong> Thermo Fisher Scientific </strong>and brochure by <strong>Shimadzu!</strong></p><h3><strong>1. Agilent Technologies: Analysis of High Purity Titanium Using an </strong><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=9500"><strong>Agilent 9500 ICP-QQQ</strong></a></h3><p><strong>Ensuring purity and performance of titanium materials used in high-tech industries&nbsp;</strong></p><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_high_purity_titanium_9500_icp_qqq_5994_9024en_agilent_56ab5e943b.pdf"><strong>Full PDF for download</strong></a></li></ul><h5><strong>Importance of high-purity titanium and the role of ICP-QQQ&nbsp;</strong></h5><p>High-purity titanium (Ti) is a critical material in high-tech industries such as semiconductor manufacturing and aerospace engineering. In semiconductor applications, Ti is widely used as a sputtering target for thin-film deposition, where even trace levels of impurities can negatively affect film uniformity, electrical properties, and device reliability. In aerospace applications, Ti is valued for its high strength-to-weight ratio and corrosion resistance, making it an ideal material for engine components and structural parts. However, any impurities can compromise the mechanical integrity and diminish the long-term performance of components, especially when operating under extreme conditions.</p><p>Ensuring the reliability and functionality of Ti in these demanding environments requires precise quantification of trace impurities in the raw material. Triple quadrupole Inductively Coupled Plasma Mass Spectrometry (ICP-QQQ) provides robust suppression of spectral interferences and ultra-low detection limits (DLs), enabling accurate determination of impurities at or below the 1 mg/kg (ppm) level in the solid. This level of sensitivity is particularly important for quality control (QC) of high-purity Ti, where conventional techniques such as XRF, ICP-OES, and GD-MS lack the sensitivity and DLs.&nbsp;</p><p>For unrivalled interference reduction using reactive cell gases, Agilent ICP-QQQ instruments include two unit mass (1 u) quadrupole mass filters, Q1 and Q2.1 Q1 is positioned before the collision/reaction cell (CRC) to select which ions enter the cell for reaction with the cell gas. Q2 filters ions that exit the cell before they pass to the detector. This tandem mass spectrometer (MS/MS) operation allows for unmatched control of reaction chemistry in the CRC, making the technique useful for handling intense spectral interferences, including polyatomic, doubly charged ion (M++), isobaric, and peak overlap interferences.&nbsp;</p><p>Using the newly developed <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=9500"><strong>Agilent 9500 Triple Quadrupole ICP-MS</strong></a> featuring a Dual-Cell System (DCS) CRC and equipped with an optional m-lens, analysts can confidently analyze Ti matrix samples and verify material purity over extended measurement periods. The m-lens is designed with an optimized geometry that minimizes background signals from easily ionized elements that can deposit on interface components during long runs. This feature enables the instrument to maintain high-power, matrix-tolerant plasma conditions while achieving ultralow background equivalent concentrations (BECs), which is critical for ppt-level impurity analysis. Operating the DCS with a suitable cell gas effectively controls spectral interferences from Ti-based species (Ti²+ and TiO+ ) that impact elements like sodium (Na), magnesium (Mg), copper (Cu), and zinc (Zn). Together with the m‑lens, this approach ensures accurate measurement of trace elemental impurities, enabling compliance within stringent industry standards. The effectiveness of the m‑lens in minimizing background signals and enabling ppt‑level impurity analysis under robust plasma conditions has also been demonstrated in high-matrix applications using ICP‑QQQ.2, 3 In addition to interference control, the 9500 ICP-QQQ system’s robustness and reproducibility make it well suited for routine analysis in both research and production settings. This capability supports the continued advancement of high-tech applications that rely on ultra-clean titanium.</p><p>In this study, a 200 ppm Ti solution prepared from a high-purity Ti powder was used to represent a typical sample encountered in advanced material analysis. The performance of the 9500 ICP-QQQ for quantifying trace impurities, including Na, Mg, Cu, and Zn, in a high Ti matrix was assessed through spike-recovery experiments and long-term stability tests.</p><h4><strong>Conclusion&nbsp;</strong></h4><p>This study demonstrated the effectiveness of the Agilent 9500 ICP-QQQ with m-lens for the ultra-trace analysis of impurity metals in high-purity titanium. By applying optimized reaction gas conditions and mass-shift techniques, spectral interferences from Ti-based species such as Ti²+ and TiO+ were successfully mitigated, enabling accurate quantification of elements like Mg, Cu, and Zn.&nbsp;</p><p>The method achieved limits of quantification in the sub-ppm range for the undiluted Ti digestion solution and maintained stable ISTD signals over extended measurement periods. Spike recovery tests confirmed high accuracy and reproducibility, with most elements showing recoveries within ±10% and RSDs below 3%.&nbsp;</p><p>These results confirm that the 9500 ICP-QQQ is a robust and reliable tool for quality control of high-purity Ti, supporting its critical applications in semiconductor and aerospace industries where impurity levels must be strictly controlled.</p><h3><strong>2. Shimadzu: Scanning Probe Microscope /Atomic Force Microscope SPM-9700HT Plus</strong></h3><ul><li>Brochure</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/c147_e021_4c550d3be3.pdf"><strong>Full PDF for download</strong></a></li></ul><p>The <strong>Shimadzu SPM-9700HT Plus</strong> is a high-throughput <strong>scanning probe microscope (SPM) / atomic force microscope (AFM)</strong> designed for three-dimensional surface imaging and nanoscale characterization of material properties across a broad range of scientific and industrial applications. The system combines high-resolution topographical imaging with multiple AFM measurement modes, including contact, dynamic, phase, lateral force, force modulation, and force-curve measurements, while optional modules extend its capabilities to techniques such as Kelvin probe force microscopy (KPFM), magnetic force microscopy (MFM), conductive AFM, piezoresponse force microscopy (PFM), and scanning tunneling microscopy (STM). A wide selection of interchangeable scanners, environmental accessories, optical microscope units, and specialized sample holders enables the instrument to be configured for diverse analytical requirements.</p><p>A major focus of the brochure is the system's emphasis on automation and ease of use through Shimadzu's <strong>Analytical Intelligence</strong> technology. Features such as <strong>Observation Navigation</strong>, <strong>NanoAssist</strong>, and the optional <strong>Cantilever Master</strong> automate instrument setup, cantilever installation, optimization of imaging parameters, and measurement workflows, allowing operators with varying levels of experience to acquire high-quality, reproducible AFM data. The redesigned control electronics and scanning system also enable high-throughput imaging and rapid physical property mapping while maintaining nanoscale resolution. In addition, the head-slide mechanism simplifies sample exchange without removing the cantilever, increasing productivity during routine measurements.</p><p>Beyond surface topography, the <strong>SPM-9700HT Plus</strong> provides extensive quantitative analysis capabilities through integrated software for roughness measurements, particle analysis, cross-sectional profiling, and morphological characterization. Optional <strong>Nano 3D Mapping Fast</strong> technology extends the instrument to nanoscale mechanical property measurements by performing force-curve mapping, allowing localized evaluation of adhesion, Young's modulus, and other mechanical properties of thin films, polymers, biomaterials, and soft samples. The optional Particle Analysis Software further enables automated extraction, classification, statistical evaluation, and export of particle size and morphology data for large datasets.</p><p>The brochure demonstrates the versatility of the platform through numerous application examples spanning <strong>electronics, semiconductor devices, magnetic materials, life sciences, industrial materials, batteries, polymers, nanomaterials, food science, and chemistry</strong>. Representative studies include magnetic domain imaging, organic thin-film transistor characterization, collagen and DNA visualization, live-cell imaging, lithium-ion battery electrode and separator analysis, photocatalyst surface potential measurements, polymer phase imaging, cellulose nanofiber characterization, and beer yeast morphology. Together, these examples highlight the <strong>Shimadzu SPM-9700HT Plus</strong> as a comprehensive AFM platform capable of combining rapid imaging, advanced nanoscale property mapping, and automated data analysis for both research and routine industrial quality control.</p><h3><strong>3. Thermo Fisher Scientific: Enhancing Monoclonal Antibody Yield and Quality Through Automated Multi-Component Feedback Control Loops Using the MarqMetrix All-In-One Process Raman Analyzer</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/enhancing_monoclonal_antibody_an1506_en_bba763e865.pdf"><strong>Full PDF for download</strong></a></li></ul><p>The application of Raman spectroscopy for real-time monitoring and control of bioreactors marks a significant advancement in bioprocessing technology. Over the past decade, its adoption has enabled tighter control of critical process parameters (CPPs), offering early indicators of process performance to ensure consistency and improve product quality. Raman spectroscopy leverages the unique vibrational signatures of molecules, allowing for highly specific detection even in complex biological matrices. This enables simultaneous, real-time monitoring of multiple CPPs, including nutrient concentrations, metabolic by-products, and cell density. As a result, users gain deep, real-time insights into cellular metabolism and can implement more dynamic, adaptive feeding strategies based on metabolic network understanding.&nbsp;</p><p>Previous studies have demonstrated the negative impact of high lactate on cell health and quantity and quality of titer produced.² In this study, we demonstrate the successful implementation of process Raman analyzer for simultaneous multi-component feedback control of glucose and lactate in a bioreactor. By continuously monitoring both analytes, the feedback control loop dynamically maintained a constant total carbon concentration (glucose + lactate) at a setpoint of 2 g/L.&nbsp;</p><p>This advanced carbon-source-based control strategy ensured that cellular metabolic demands were met while promoting lactate consumption toward the end of the run. As a result, lactate accumulation was significantly reduced, leading to substantial improvements in titer yield, product quality, and cell viability compared to standard bolus feeding strategies (Figure 2).</p><p>The outcomes of this work underscore the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2233"><strong>Thermo Scientific™ MarqMetrix™ All-In-One Process Raman Analyzer </strong></a>as a key Process Analytical Technology (PAT) tool-enabling real-time, multi-analyte control for any biomanufacturer seeking to engage in intelligent, automated biomanufacturing.</p><h4><strong>Conclusion&nbsp;</strong></h4><h5><strong>1. Unmatched Real-Time Control Capability:&nbsp;</strong></h5><p>Maintaining a constant total carbon concentration (glucose + lactate) of 2 g/L in dynamic bioreactor environments demands precise, simultaneous analyte monitoring. The MarqMetrix All-In-One Process Raman Analyzer delivers near real-time, high-fidelity data every two minutes, empowering advanced control strategies that are simply not feasible with conventional technologies. This makes it an indispensable PAT tool for modern bioprocessing.&nbsp;</p><h5><strong>2. Proven Impact on Product Yield and Quality:&nbsp;</strong></h5><p>The Raman-enabled carbon control strategy resulted in a &gt;10% increase in titer and a reduction in glycation by 83% and 66% compared to continuous and fed-batch glucose control, respectively. These outcomes underscore the analyzer’s transformative impact on both product quantity and quality.&nbsp;</p><h5><strong>3. Versatile Automation Across Bioprocesses:&nbsp;</strong></h5><p>All three bioreactor runs—each employing distinct control logics (Table 2)—were successfully managed through automated feedback using the process Raman analyzer. Its flexible design, including easily swappable probes, supports seamless adaptation to other critical metabolites such as amino acids, making it a universal solution for bioprocess control.&nbsp;</p><h5><strong>4. Foundation for Intelligent Manufacturing:&nbsp;</strong></h5><p>With its real-time, data-rich insights and seamless integration into automated systems, the MarqMetrix All-InOne analyzer is not just a monitoring tool; it is a cornerstone technology for intelligent, AI-driven biomanufacturing. It enables consistent, high-quality production while reducing time, cost, and variability.</p>

News from LabRulezICPMS Library - Week 27, 2026

Article

Webinars

Application

Academy

Eurachem is a European network promoting international traceability of chemical measurements and good analytical practice. It provides expert guidance, supports method validation, uncertainty evaluation, proficiency testing, and facilitates discussion on technical and policy issues in analytical quality.

Eurachem

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Thermo Scientific™ picoSpin™ 80 Series II NMR Spectrometer

Benchtop 82 MHz NMR spectrometer with high resolution and no cryogens. Ideal for teaching, reaction monitoring, and small-molecule analysis in any lab.

<div><h4><strong>Compact, high-resolution benchtop NMR for education, research, and process control</strong></h4><p><strong>The picoSpin™ 80 Series II NMR spectrometer brings the power of Nuclear Magnetic Resonance (NMR) to laboratories of any size. With a compact footprint, temperature-stabilized 2 Tesla permanent magnet, and proton Larmor frequency of 82 MHz, the instrument delivers chemical shift resolution below 20 ppb—unmatched among benchtop NMR systems.</strong></p><p>Designed for users of all experience levels, the picoSpin 80 is ideal for structural analysis, compound identification, reaction monitoring, and education. It operates without cryogens or deuterated solvents and requires only 40 µL of liquid sample, introduced via a replaceable capillary cartridge.</p><h3><strong>Key Benefits</strong></h3><ul><li><strong>High-resolution performance</strong> for routine small molecule applications</li><li><strong>Compact and portable</strong>—placeable on bench or near reactors</li><li><strong>Low operating cost</strong>—no cryogens, no consumables, standard power supply</li><li><strong>Easy to use</strong>—automatic shimming, minimal training required</li><li><strong>Fast data acquisition</strong>—NMR spectrum delivered in minutes</li></ul></div><h3><strong>Applications</strong></h3><p><strong>Pharmaceutical &amp; Chemical Research</strong><br>Gain rapid insight into reaction progress and sample composition without relying on centralized NMR facilities. The 82 MHz field strength ensures better signal dispersion and structural clarity than lower-frequency desktop systems.</p><p><strong>Education</strong><br>Provide hands-on experience with real NMR spectra. The intuitive web interface and included Mnova™ software allow students to operate the instrument and analyze data independently, with no re-shimming required between measurements.</p><p><strong>Process Analysis &amp; QA/QC</strong><br>Built for rugged environments, the instrument fits easily into production labs or fume hoods. Monitor reactions in real time and ensure reproducibility through a stable magnetic field and network-based remote access.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_80_Series_II_NMR_Spectrometer_7_7a843b395f.jpg" alt="Thermo Scientific™ picoSpin™ 80 Series II NMR Spectrometer: 82MHz spectrum of Oil of Wintergreen resolves neighboring multiplets and reveals small couplings." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_80_Series_II_NMR_Spectrometer_7_7a843b395f.jpg 200w," sizes="100vw" width="1056" height="825"></p><h3><strong>Interface &amp; Data Handling</strong></h3><ul><li><strong>Web-based control</strong> from PC, tablet, or smartphone</li><li><strong>Data export</strong> in JCAMP-DX format, compatible with most NMR software</li><li><strong>Mnova™ software license</strong> included (1 year) for advanced analysis</li><li><strong>Ethernet connectivity</strong> for remote monitoring and control</li></ul><h3><strong>Technical Specifications</strong></h3><ul><li><strong>Magnet</strong>: 2 Tesla rare earth permanent, temperature stabilized</li><li><strong>Larmor Frequency</strong>: 82 ± 2 MHz (proton)</li><li><strong>Spectral Resolution</strong>: ≤ 20 ppb FWHM</li><li><strong>Sample Volume</strong>: 40 µL (injected via syringe)</li><li><strong>Capillary Cartridge</strong>: 400 µm ID, 1/16 in. fittings, user replaceable</li><li><strong>Power Supply</strong>: 100–230 V AC, 50/60 Hz, 150 W</li><li><strong>Environmental Requirements</strong>: Standard lab environment, no cryogens or compressed gases</li><li><strong>Dimensions</strong>: 43 × 35.6 × 25.4 cm</li><li><strong>Weight</strong>: 19 kg (43 lb)</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_80_Series_II_NMR_Spectrometer_4_267f669007.jpg" alt="Thermo Scientific™ picoSpin™ 80 Series II NMR Spectrometer: Easily operate your system through a web-browser for remote access, automatic shimming and single-click data collection." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_80_Series_II_NMR_Spectrometer_4_267f669007.jpg 222w," sizes="100vw" width="1053" height="739"></p>

Thermo Scientific™ picoSpin™ Accessories

Enhance your nuclear magnetic resonance (NMR) spectroscopy analysis with a complete set of accessories designed to help you get the most from your Thermo Scientific™ picoSpin™ NMR Spectrometer.

<div><div><p><strong>Enhance your nuclear magnetic resonance (NMR) spectroscopy analysis with a complete set of accessories designed to help you get the most from your Thermo Scientific™ picoSpin™ NMR Spectrometer. Whether in the classroom or in a chemical manufacturing QA/QC lab, valuable picoSpin accessories will help you achieve the progress that only personal NMR can offer for your research, teaching or process applications.</strong></p></div><div><h3><strong>Choose from these picoSpin accessories:</strong></h3><h4><strong>Benchtop NMR Reaction Monitoring Accessory</strong></h4><p>Adding a reaction monitoring accessory to the <strong>Thermo Scientific™ &nbsp;picoSpin™ 45</strong> or the <strong>picoSpin 80 NMR spectrometer</strong> gives organic chemistry students valuable hands-on experience of chemical reaction mechanisms, kinetics, &nbsp;thermodynamics, and other physical organic properties to complement the core of your undergraduate chemistry curriculum.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_Accessories_16_4378eed143.jpg" alt="Thermo Scientific™ picoSpin™ Accessories: Benchtop NMR Reaction Monitoring Accessory" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_Accessories_16_4378eed143.jpg 198w," sizes="100vw" width="650" height="513"></p><p>The new reaction monitoring accessory for high-resolution benchtop picoSpin spectrometers uses a pump and computer-actuated valve operator to quickly and automatically direct samples from a chemical reaction to the spectrometer for data acquisition. The instrument generates real-time, information-rich images about the state of the chemical reaction as each NMR spectrum is automatically processed and analyzed.&nbsp;</p><p>The picoSpin NMR spectrometer’s fluid capillary system is perfectly suited to an online flow configuration; eliminates the need for fragile NMR tubes and messy preparation when the time comes for the next timed sampling of the reaction mixture.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_Accessories_17_10838af3e0.jpg" alt="Thermo Scientific™ picoSpin™ Accessories: Benchtop NMR Reaction Monitoring Accessory" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_Accessories_17_10838af3e0.jpg 245w," sizes="100vw" width="650" height="296"></p><ul><li>Reaction Monitoring lesson plan for teaching</li><li>Low-maintenance NMR accessory</li><li>Real time operation</li><li>Enhance chemistry curriculums</li><li>Provide a richer experience in spectroscopy</li><li>Integrated into an installed picoSpin instrument</li><li>Included as part of a new instrument purchase</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_Accessories_18_b8591d5e7e.jpg" alt="Thermo Scientific™ picoSpin™ Accessories: Benchtop NMR Reaction Monitoring Accessory" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_Accessories_18_b8591d5e7e.jpg 245w," sizes="100vw" width="650" height="373"></p><h4><strong>Thermo Scientific™</strong>&nbsp;<strong>picoSpin™&nbsp;NMR Classroom Kit for 1/16-inch and 1/32-inch Fittings</strong></h4><p>Each kit provides sample injection accessories for use with the picoSpin NMR spectrometer. The kits include polypropylene syringes, syringe filters, inlet and outlet port plugs, inline filters, and drain tubes. Also included are easy to use instructions describing sample injection into the picoSpin NMR spectrometer using accessories in this kit.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_Accessories_5_a6ea2283b8.jpg" alt="Thermo Scientific™ picoSpin™ Accessories: Thermo Scientific™&nbsp;picoSpin™&nbsp;NMR Classroom Kit for 1/16-inch and 1/32-inch Fittings" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_Accessories_5_a6ea2283b8.jpg 245w," sizes="100vw" width="650" height="321"></p><h4><strong>Thermo Scientific™&nbsp;picoSpin™ NMR Laboratory Kit for 1/16-inch and 1/32-inch Fittings</strong></h4><p>Each kit provides sample injection accessories for use with the picoSpin NMR spectrometer. The kits include a 100 μL Hamilton Gastight™ syringe, a 22 gauge blunt-tip needle with inlet port adapter (for 1/16-inch fittings), &nbsp;a 26s gauge blunt-tip needle with inlet port adapter (for 1/32-inch fittings), inline filter, drain tube assembly, and a pair of inlet and outlet port plugs. Instructions describing sample injection into the picoSpin NMR spectrometer using accessories are included.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_Accessories_7_8a97301229.jpg" alt="Thermo Scientific™ picoSpin™ Accessories: Thermo Scientific™&nbsp;picoSpin™ NMR Laboratory Kit for 1/16-inch and 1/32-inch Fittings" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_Accessories_7_8a97301229.jpg 245w," sizes="100vw" width="650" height="351"></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_Accessories_15_0f8ec6822c.jpg" alt="Thermo Scientific™ picoSpin™ Accessories: Thermo Scientific™&nbsp;picoSpin™ NMR Laboratory Kit for 1/16-inch and 1/32-inch Fittings" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_Accessories_15_0f8ec6822c.jpg 245w," sizes="100vw" width="650" height="292"></p><h4><strong>Thermo Scientific™&nbsp;picoSpin™ Inline Filter Kit</strong></h4><p>This kit provides inlet filters for use with the picoSpin NMR spectrometer. The kit includes a 5 replacement, 2 μm stainless steel mesh inlet filters for 1/16-inch fittings.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_Accessories_4_f203223c20.jpg" alt="Thermo Scientific™ picoSpin™ Accessories: Thermo Scientific™&nbsp;picoSpin™ Inline Filter Kit" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_Accessories_4_f203223c20.jpg 245w," sizes="100vw" width="650" height="400"></p><h4><strong>Mnova™ NMR</strong>&nbsp;</h4><p>The Mnova NMR plugin is ideal both for the non-expert NMR user looking for an easy to learn software which delivers quick, high quality results, and for the expert user looking for extensive advanced functionality.</p><h4><strong>Mnova™&nbsp;NMRPredict Desktop</strong></h4><p>NMRPredict Desktop allows Prediction of 1D (1H, 13C, 15N, 19F, 31P, 17O, 29Si) and HSQC from molecular structure (mol file, ChemDraw, IsisDraw, ChemSketch) within Mnova. Easily combine and compare experimental and predicted data as part of your workflow and leverage your company’s unique knowledge.</p><h4><strong>Travel Case for the&nbsp;Thermo Scientific™&nbsp;picoSpin™ 80 NMR</strong></h4><p>Make the most of system portability with a handy travel case.</p><h4><strong>Replacement Capillary Cartridge</strong></h4><p>The replacement Capillary Cartridge includes the fluid sub-panel assembly, the sample capillary, the NMR RF coil and the NMR shim coils. Replacement of the Capillary Cartridge is necessary when the 300 μm ID sample delivery tubing becomes clogged or contaminated. &nbsp;To minimize downtime it is advisable to keep a spare cartridge in stock. &nbsp;The picoSpin Capillary Cartridge comes complete with the tools needed for installation and removal. Capillary cartridges come standard with 1/16-inch fittings. Cartridges with 1/32-inch fittings are available by special order.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_Accessories_11_c087685ee3.jpg" alt="Thermo Scientific™ picoSpin™ Accessories: Replacement Capillary Cartridge" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_Accessories_11_c087685ee3.jpg 245w," sizes="100vw" width="650" height="206"></p><h4><strong>Thermo Scientific™&nbsp;picoSpin™ Cartridge Maintenance Kit for 1/32-inch Fittings</strong></h4><p>This kit provides accessory items needed to perform maintenance on the capillary inlet filter of the picoSpin NMR spectrometer. &nbsp;The kit includes 1/4” and 3/16” inch open-end box wrenches, 10 replacement 2 μm frit filters, and 2 short pieces of wire to help with the removal of frit. &nbsp;Instructions are included describing how to ‘back-flush’ clean the existing frit filter and how to replace a frit filter.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_Accessories_14_8f72ac1f3b.jpg" alt="Thermo Scientific™ picoSpin™ Accessories: Thermo Scientific™&nbsp;picoSpin™ Cartridge Maintenance Kit for 1/32-inch Fittings" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_Accessories_14_8f72ac1f3b.jpg 241w," sizes="100vw" width="650" height="421"></p></div></div>

Thermo Scientific™ picoSpin™ 45 Series II NMR Spectrometer

Affordable, compact NMR spectrometer for research, education, or QC. 30 μL sample volume, web GUI, auto shimming, replaceable capillary, and 1-year Mnova™ software license included.

<div><div><p><strong>Get a dedicated NMR spectrometer for your research, manufacturing process, or classroom with the affordable Thermo Scientific™ picoSpin™ 45 Series II NMR Spectrometer. A true breakthrough in chemical instrumentation, the picoSpin 45 occupies only a fraction of the space of a conventional NMR system and requires no specialized training to operate. Simply inject 30 microliters of liquid sample into the internal capillary via front-panel fittings to obtain a high-quality spectrum.</strong></p><p>The Series II model offers streamlined workflows, a modern web-based interface, automatic shimming, and customizable methods — ideal for both novice and experienced users.</p><p>A temperature-stabilized permanent magnet ensures consistent, maintenance-free performance with no need for cryogens. NMR data is generated in the industry-standard JCAMP-DX format, compatible with common NMR analysis software. The internal capillary is housed in a replaceable cartridge, allowing users to easily swap it out if blocked or contaminated.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_80_Series_II_NMR_Spectrometer_0b279c7ee9.jpg" alt="Thermo Scientific™ picoSpin™ 45 Series II NMR Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_80_Series_II_NMR_Spectrometer_0b279c7ee9.jpg 245w," sizes="100vw" width="2505" height="1157"></p><h3><strong>Key Features:</strong></h3><ul><li>High-performance, high-resolution, compact, and portable design</li><li>Easy to use — no specialized training required</li><li>Replaceable capillary cartridge</li><li>Microcoil capillary probe</li><li>Fully programmable pulse sequencer</li><li>Ethernet connectivity</li><li>Web-based graphical user interface</li><li>Includes a one-year license for Mnova™ NMR software</li><li>Sample volume: 30 μL</li></ul><h3><strong>Specifications:</strong></h3><ul><li><strong>Capillary Cartridge:</strong> 400 µm ID, 30 µL volume, 1/16 in. fittings, user-replaceable</li><li><strong>Electrical Requirements:</strong> 100/230 V, 50/60 Hz, 150 W</li><li><strong>Environment:</strong> No cryogens or compressed gases required; standard lab environment</li><li><strong>Magnet:</strong> Rare earth permanent magnet, 1.1 Tesla, temperature stabilized</li><li><strong>Performance:</strong> Larmor Frequency 45 ± 1 MHz (proton), chemical shift resolution ≤ 40 ppb (FWHM)</li><li><strong>Data Output:</strong> JCAMP-DX format, compatible with standard NMR programs</li><li><strong>Sample Introduction:</strong> Syringe injection</li><li><strong>Dimensions (W × D × H):</strong> 14.6 × 17.8 × 29.2 cm (5.75 × 7 × 11.5 in.)</li><li><strong>Weight:</strong> 4.8 kg (10.5 lb)</li><li><strong>Unit Size:</strong> Each</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_45_Series_II_NMR_Spectrometer_34cde1c4c1.jpg" alt="Thermo Scientific™ picoSpin™ 45 Series II NMR Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_45_Series_II_NMR_Spectrometer_34cde1c4c1.jpg 245w," sizes="100vw" width="650" height="365"></p></div></div>

Products focused on NMR - page 1

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