<div><div>Researchers led by <a target="_blank" rel="noopener noreferrer" href="https://kudova.group.uochb.cz/en">Eva Kudová</a> from IOCB Prague and Jitka Viktorová from UCT Prague have identified new androstane-based steroid derivatives that can significantly improve the effectiveness of existing antibiotics against multidrug-resistant Staphylococcus aureus.</div></div><div>The team screened dozens of natural steroidal hormones and synthetic derivatives to see whether they could block bacterial efflux pumps – mechanisms that bacteria use to eject antibiotics and survive treatment. Two compounds emerged as particularly promising: they inhibited efflux pumps and lowered the effective doses of antibiotics such as ciprofloxacin and erythromycin.Further analysis showed that one of the compounds also suppressed genes linked to bacterial virulence. Another key finding is that the most active molecules are non-toxic to human immune cells and showed no detectable endocrine activity, suggesting a favorable safety profile.These findings support the idea that rationally designed steroid-based molecules could act as antibiotic adjuvants, helping existing drugs overcome bacterial resistance.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/IOCB_Prague_Steroidal_hormones_and_neurosteroids_novel_therapeutic_strategies_in_bacterial_infections_8e5d2a7b48.jpg" alt="IOCB Prague: Steroidal hormones and neurosteroids – novel therapeutic strategies in bacterial infections" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_IOCB_Prague_Steroidal_hormones_and_neurosteroids_novel_therapeutic_strategies_in_bacterial_infections_8e5d2a7b48.jpg 222w," sizes="100vw" width="1258" height="886"><blockquote><h4>Original Article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S0223523426001613?via%3Dihub">Steroidal hormones and neurosteroids - novel therapeutic strategies in bacterial infections: Design, synthesis, and biological evaluation</a></h4>Daniela Brdová, Bára Křížkovská, Jan Špaček, Zdeněk Míchal, Eva Jablonská, Ondřej Strnad, Hana Chodounská, Eszter Szánti-Pintér, Marina Morozovová, Václav Hanžl, Jan Tkadlec, Martijn Riool, Jan Lipov, Jitka Viktorová, Eva Kudová&nbsp;Eur. J. Med. Chem., 2026, 308, 118716<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1016/j.ejmech.2026.118716">https://doi.org/10.1016/j.ejmech.2026.118716</a><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote><h4>Abstract</h4>The global rise of antibiotic resistance necessitates novel therapeutic strategies for infectious diseases. Inhibition of bacterial efflux pumps, which contribute to multidrug resistance, represents a promising approach to restore or even increase the efficacy of existing antibiotics. Using fluorescence-based ethidium bromide accumulation, broth microdilution, and checkerboard assays, we evaluated 26 endogenous steroidal hormones and neurosteroids, along with 30 synthetic derivatives, for their ability to enhance antibiotic susceptibility in multidrug-resistant Staphylococcus aureus. Structure-activity relationship analysis identified compounds 13 and 16 as lead candidates, exhibiting strong efflux pump inhibition and marked reductions in the minimum inhibitory concentrations of ciprofloxacin and erythromycin. Both compounds showed additive effects in checkerboard assays. Modifications at C-3 (polar substitution) and C-17 (3α,5β-stereochemistry and nonpolar substitution) were essential for potent efflux inhibition and sensitization, although these modifications were not additive when combined. Transcriptome analysis further revealed that compound 13 significantly downregulated S. aureus virulence-associated genes when administered alone or in combination with antibiotics. Cytotoxicity assessment in human peripheral blood mononuclear cells and receptor transactivation assays for estrogen, androgen, and progesterone receptors indicated that the most active derivatives were non-toxic and lacked detectable endocrine activity, suggesting a favorable safety profile. Overall, these findings support the concept that rationally designed andostane-based steroidal scaffolds can function as competitive bacterial efflux pump inhibitors and serve as potential antibiotic adjuvants to mitigate efflux-mediated resistance.<h4>Instrumentation</h4><h5>Structural characterization</h5><ul><li>AVANCE III 400 MHz NMR spectrometer (Bruker)</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?mainauthorItems=3&amp;search=LTQ+Orbitrap+XL">LTQ Orbitrap XL HRMS</a> (Thermo Fisher Scientific, ESI)</li></ul></div>

Steroidal hormones and neurosteroids – novel therapeutic strategies in bacterial infections

Wiley, a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation and learning, today announced the release of additional data to its IR and Raman spectral libraries, significantly broadening compound coverage, including materials, polymers, minerals, and others.This latest release includes the first installment of Raman spectra from Wiley's collaboration with the American Museum of Natural History (AMNH), announced earlier this spring, drawing from one of the world's most important mineral collections.“Researchers depend on reference data as a foundation for sound scientific decisions,” said Graeme Whitley, senior director, data science solutions at Wiley. “Continuous updates ensure scientists always have the most current, reliable reference libraries at their fingertips, helping them work faster and make confident decisions when it matters most.”<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_Wiley_expands_its_trusted_IR_and_Raman_spectral_library_collections_helping_analytical_labs_make_faster_more_confident_decisions_1a54aaad3a.jpg" alt="Wiley: Wiley expands its trusted IR and Raman spectral library collections—helping analytical labs make faster, more confident decisions" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Wiley_Wiley_expands_its_trusted_IR_and_Raman_spectral_library_collections_helping_analytical_labs_make_faster_more_confident_decisions_1a54aaad3a.jpg 245w," sizes="100vw" width="1600" height="856"><h4>Summary of updates:</h4><h5>KnowItAll Raman Spectral Library Collection</h5><ul><li>Added: 1,213 spectra</li><li>Now contains: 29K+ spectra</li></ul>2 new databases:<ul><li>Raman – American Museum of Natural History Minerals – Wiley – 198 spectra</li><li>Raman – Microbiology – 71 spectra</li></ul>Spectra added to databases:<ul><li>Raman – Consumer Goods &amp; Food-Related Compounds – +104</li><li>Raman – Drugs – +128</li><li>Raman – Materials – +132</li><li>Raman – Minerals – +233</li><li>Raman – Polymers – +5</li><li>Raman – Pigments &amp; Dyes – +342</li></ul><h5>KnowItAll IR Spectral Library Collection</h5><ul><li>Added: 949 spectra</li><li>Now contains: 344K+ spectra</li></ul>7 new databases:<ul><li>ATR-IR – Clinical – 364 spectra</li><li>ATR-IR – Materials – 10 spectra</li><li>ATR-IR – Pigments &amp; Dyes – 420 spectra</li><li>ATR-IR – Polymers – 21 spectra</li><li>IR – Clinical – 20 spectra</li><li>IR – Materials – 17 spectra</li><li>IR – Microbiology – 75 spectra</li></ul>Spectra added to databases:<ul><li>IR – Minerals – +5</li><li>IR – Polymers – +17</li></ul>Spectral library subscribers automatically gain access to new data, ensuring labs always have the most current, reliable reference libraries to improve analysis, reduce errors, and increase productivity.<ul><li>Learn more at: <a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/spectral-databases/">www.sciencesolutions.wiley.com/spectral-databases</a></li><li>Existing subscribers can access step-by-step guidance on updating their KnowItAll databases at <a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/how-to-update-knowitall-databases">https://sciencesolutions.wiley.com/how-to-update-knowitall-databases</a></li></ul><h5>Wiley Spectral Databases</h5>Wiley's spectral databases are consistently evolving to meet today's research demands, covering multiple spectral techniques across a wide range of applications including polymers, materials, environmental, forensics, toxicology, pharmaceutical, biotech, automotive, aerospace, food, cosmetics, and more. Built on rigorous quality protocols, Wiley delivers industry-leading spectral data and intelligent tools to accelerate analysis and deliver deeper insights — making it the authoritative, trusted source that analytical labs worldwide rely on.&nbsp;<h5>About Wiley</h5>Wiley (NYSE: WLY) is a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation, and learning. With more than 200 years at the center of the scholarly ecosystem, Wiley combines trusted publishing heritage with AI-powered platforms to transform how knowledge is discovered, accessed, and applied. From individual researchers and students to Fortune 500 R&amp;D teams, Wiley enables the transformation of scientific breakthroughs into real-world impact. From knowledge to impact—Wiley is redefining what's possible in science and learning.&nbsp;

Wiley expands its trusted IR and Raman spectral library collections

Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 4th May 2026? Check out new documents from the field of spectroscopy/spectrometry and related techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">LabRulezGCMS</a> libraries.</blockquote>This week we bring you application notes by KNAUER, Shimadzu, and Thermo Fisher Scientific!<h3>1. KNAUER: Analysis of HPLC fractions by Benchtop NMR</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/knauer_hplc_benchtop_nmr_web_638c60e13c.pdf">Full PDF for download</a></li></ul>Preparative HPLC is essential for isolating compounds and removing impurities in pharmaceutical and chemical industries. Non-destructive, fast analysis is preferred to maintain yield and enable at-line monitoring, avoiding lengthy sample preparation. Recent advancements in benchtop NMR spectrometers (up to 90 MHz) allow quick analysis without deuterated solvents. In this proof-of-concept study we purified a pharmaceutical sample via HPLC and confirmed its identity using benchtop NMR. Fractions (0.7–4.4 mM) were analyzed without preparation, using only 300 µL per sample, ensuring rapid batch control with no product loss. This study demonstrates the seamless integration of HPLC and benchtop NMR.<h4>Experimental</h4><h5>Preparative HPLC Method</h5>Eluent 20:80 Ethanol/water, isocratic mode, flow rate 12.5 ml/min, detection UV254 nm 2 Hz, 500 µl stacked injection, automated fractionation with threshold function, column temperature ambient, Column Eurospher II 100-10 C18 150x20 mm&nbsp;<h5>Analytical HPLC Method</h5>Eluent 20:80 Ethanol /water + 0.1% formic acid, isocratic mode, flow rate 1 ml/min, detection UV254 nm 10 Hz, 5 µl partial loop injection, column temperature 25 °C, Column <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1633">Eurospher II 100-5 C18</a> 150x4 mm&nbsp;<h5>NMR Method&nbsp;</h5>NMR spectra were acquired on a Magritek Multi-X Ultra 80 MHz benchtop NMR system using an adapted WET sequence for solvent suppression. 32 scans were acquired with a repetition time of 15s. WET parameters were adjusted for each sample to yield optimal suppression for all solvent signals. Pooled HPLC fractions were analysed directly without addition of deuterated solvents or other sample preparation.<h4>Conclusion</h4>This proof-of-concept study successfully shows that HPLC and benchtop NMR can be used together easily. Samples can be analyzed non-destructively within minutes and without any further preparation due to highly efficient suppression of multiple solvent signals. Compounds can be identified without the need of reference standards. This study shows that NMR can provide a valid compatible alternative detector for HPLC fraction analysis.<h3>2. Shimadzu: DIC Analysis in High-Speed Tensile Test of CFRP</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_00854_en_fb6c68b858.pdf">Full PDF for download</a></li></ul><h4>User Benefits</h4><ul><li>The <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=1&amp;search=HPV-X3">HPV-X3</a> is suitable for observation of fracture of brittle materials such as CFRP because it has a maximum recording speed (framerate) of 20 Mfps.&nbsp;</li><li>The HPV-X3 provides improved DIC analysis performance, as its resolution is 3 times higher than that of the conventional highspeed video camera.</li><li>The HITS-TX impact testing machine enables testing at a maximum speed of 20 m/s</li></ul>Carbon fiber reinforced plastic (CFRP) is a material with particularly high specific strength, even among composite materials, and used in various applications such as transport aircraft, taking advantage of its excellent mechanical properties. Because CFRP consists of carbon fibers and resin, it shows complex fracture behavior, and brittle fracture progresses from damage as the point of origin. Since fracture proceeds instantaneously, a high-speed video camera with a high recording speed is necessary when observing fracture of CFRP. One method for measuring strain in a high-speed tensile test is Digital Image Correlation (DIC), which visualizes the distribution of strain at the specimen surface by comparing a random pattern on the specimen surface before and after deformation. Thus, a high-speed video camera with a high resolution is also necessary in order to improve the DIC performance.&nbsp;Newly-developed <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=1&amp;search=HPV-X3">Hyper Vision HPV-X3 high-speed video camera</a> is extremely well-suited to DIC analysis of CFRP, as its recording speed is 2 timesfaster and itsresolution is 3 times higher than the conventional HPV-X2. In this experiment, a high-speed tensile test of CFRP was conducted using a HITS-TX high-speed tensile testing machine. The condition of the test was observed with the new HPV-X3, and the strain distribution of the CFRP test piece was clarified by a DIC analysis of the recorded images.<h4>Test Piece and Test Instruments</h4>A CFRP quasi-isotropic laminate was used as the test piece. Aluminum foil was glued to the back side of the test piece, and the timing when the electrical conduction of the aluminum foil was interrupted by fracture of the test piece was used as the trigger for video recording. The HITS-TX was used in the highspeed tensile test. The HPV-X3 was used in fracture observation, and for comparison, the fracture process was also recorded with the conventional HPV-X2 camera. Fig. 1 shows the condition of the test, and Table 1 and Table 2 show the equipment composition and test conditions, respectively.<h4>DIC Analysis Results in High-Speed Tensile Test</h4>Fig. 3 shows the DIC analysis results in the high-speed tensile test. The color bar was set to display the color purple at around 0 % strain and red at around 2 % strain. Fig. 3 (1) is an image at the start of the test. After the test started, strain in the 45˚ direction concentrated from the lower left to the right central area, as can be seen in Fig. 3 (2). Then, as the test progressed, a condition of increasing strain in the initial area of strain concentration can be seen in Fig. 3 (3) to (9). A crack occurs in Fig. 3 (10), and strain decreases in the crack area. Following this, the test piece fractured completely in Fig. 3 (11) and (12), and a decrease in the strain in the area around the crack could be observed.<h4>Conclusion</h4>A high-speed tensile test of CFRP was conducted using a HITSTX high-speed tensile testing machine and the newlydeveloped HPV-X3 high-speed video camera, and the strain distribution at the time of test piece fracture was visualized by a DIC analysis. Because the HPV-X3 offers a 3 times higher resolution and a 2 times faster recording speed than the conventional device, it is a suitable high-speed video camera for fracture observation and DIC analysis in impact tests of brittle materials such as CFRP. The measurement system introduced in this Application News article is a useful tool for the development of composite materials.<h3>3. Thermo Fisher Scientific: Polymer analysis using femtosecond-laser-ablation depth profiling</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/xps_depth_profiling_polymer_analysis_appnote_c731e2e7e0.pdf">Full PDF for download</a></li></ul>X-ray photoelectron spectroscopy (XPS) is an essential polymer characterization technique that can identify not just the elemental composition but also the chemical state of polymer samples. This allows the chemical bonding environment to be deduced and, as a result, the polymer species can be identified. This can all be achieved with minimal sample preparation thanks to the built-in charge-compensation systems found in XPS instruments, which simplify the analysis of insulating samples.&nbsp;The introduction of gas cluster ion sources (GCIS), such as the Thermo Scientific™ MAGCIS Dual Mode Ion Source, marked a major step forward in polymer analysis. Unlike monatomic ion beams, GCIS are able to clean surface contamination, and etch away layers of sample material, without damaging the underlying chemistry of organic samples such as polymers. As a result, GCIS has allowed chemical-damage-free analysis to reach micrometers below the sample surface. This depth of analysis can be highly time consuming, however, and total experimental times can range from multiple hours to days.&nbsp;The addition of femtosecond-laser-ablation (fs-LA) technology is alleviating this, allowing for XPS spectra to be collected from a depth of tens of µm into a sample in a matter of minutes. This is because the laser ablation occurs on the femtosecond timescale (i.e., nearly instantaneously), effectively eliminating the material removal time of the depth profile. Additionally, unlike other material removal techniques such as atomic ion beam impact (where a collision cascade effect is induced to remove surface material) fs-LA is capable of removing material without chemical damage due to the ultrashort columbic explosion process used to eject the material. The resulting profile is therefore representative of the actual sample chemistry.<h4>Paint layer analysis&nbsp;</h4>In traditional ion-beam depth profiling, analytical depths are generally limited to several hundred nanometers, up to a micrometer. This means that it is extremely difficult to analyze the interfaces between multiple micrometer-thick layers in a sample without the use of additional techniques such as ultralow-angle microtome (ULAM) sectioning.¹ The introduction of fs-LA technology, however, allows micrometers of material to be removed rapidly, enabling the characterization of layered samples.&nbsp;As an example, a multi-layer paint specimen (provided by the University of Surrey, UK) was depth profiled using the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2206">Thermo Scientific™ Hypulse™ Surface Analysis System</a>. The sample consists of an aluminum substrate coated with a 5 µm layer of polyurethane primer followed by a 25 µm PMMA/PVdF topcoat.The depth profile was generated using a 1,030 nm laser with an energy of 250 µJ for ablation, along with a 30 µm X-ray spot size for data collection. XPS spectra were collected after each ablation cycle to obtain an atomic concentration plot through both paint layers into the substrate material (Figure 2).&nbsp;5 distinct regions throughout the analyzed depth can be seen. The top surface of the sample consists of an adventitious layer of carbon contamination, which is commonly found on samples exposed to air. The second layer is the 25 µm PVdF/PMMA topcoat, and the third layer is the PU primer. Between the primer and the final aluminum substrate layer, a clear increase in adventitious carbon is observed, similar to the signal seen at the top sample surface. This suggests residual carbon contamination was present on the substrate before the paint layers were applied.&nbsp;It would take hours to produce the XPS depth profile shown in Figure 2 using traditional ion beam approaches. Even with the use of a monatomic beam with a high energy per atom, the length of the analysis could still be just as long, depending on the sample material, and would sacrifice the chemistry of any organic/polymeric materials. The combination of fs-LA depth profiling and snapshot XPS acquisition, meanwhile, can reduce the experimental time to less than 20 minutes without inducing any chemical damage to the sample surface.<h4>Summary&nbsp;</h4>One of the most critical aspects of successful polymer XPS depth profiling is the preservation of the sample chemistry during material removal. Additionally, experiment time can be a significant limiting factor, and thicker samples could lead to reduced time for repeat experiments. The femtosecond laser ablation capabilities of the Hypulse Surface Analysis System provide fast, efficient, and chemical-damage-free material removal from a sample surface, enabling analysis multiple micrometers into a sample. This means that hidden sample interfaces, that were largely inaccessible before, can now be analyzed easily and efficiently

News from LabRulezICPMS Library - Week 19, 2026

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The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) is a leading scientific institution in the Czech Republic, recognized internationally. Its primary mission is basic research in the fields of chemical biology and medicinal chemistry, organic and material oriented chemistry, chemistry of natural compounds, biochemistry and molecular biology, physical chemistry, theoretical chemistry, and analytical chemistry. 

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

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Thermo Scientific Niton XL2 100G General Metal Analyzer

Get immediate, nondestructive elemental analysis of alloy materials from titanium to nickel with the Thermo Scientific™ Niton™ XL2 100G General Metal Analyzer. 

<div><div><div><div><div>Get immediate, nondestructive elemental analysis of alloy materials from titanium to nickel with the Thermo Scientific™ Niton™ XL2 100G General Metal Analyzer. The XL2 100G analyzer is a practical, cost-effective solution that offers fast analysis for general alloy identification, basic fabrication, and scrap metal sorting.&nbsp;This high value, high performance analyzer features advanced electronics yet it is ruggedly built to withstand the harshest environments, in the field or on the shop floor.</div><div><h3>The value choice to ensure accuracy, precision, and ease of use:</h3><ul><li>Precise elemental analysis of alloy materials</li><li>Very easy to use – even by non-technical personnel</li><li>Ruggedly designed for the most challenging industrial environments, and sealed against moisture and dust</li><li>Completely nondestructive test</li><li>Ergonomically designed&nbsp;</li><li>Customizable menus with multiple language options and daylight-readable icons</li><li>Standard analytical range of more than 25 elements from sulfur to uranium.</li></ul></div></div><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XL_2_100_G_General_Metal_Analyzer_340e83faa3.jpg" alt="Thermo Scientific™ Niton™ XL2 100G General Metal Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XL_2_100_G_General_Metal_Analyzer_340e83faa3.jpg 156w," sizes="100vw" width="650" height="650"><h3>Specifications</h3><ul><li>Analytical Range: 25 elements from Ti to Bi</li><li>Available Analytical Modes: Alloy Modes: Metal Alloy</li><li>Certifications/Compliance: CE, RoHS</li><li>Data Entry:&nbsp;<ul><li>Touch-screen keyboard</li><li>User-programmable pick lists</li><li>Optional wireless remote barcode reader</li></ul></li><li>Data Storage: Internal &gt;10,000 readings with spectra</li><li>Data Transfer: USB, Bluetooth™, and RS-232 serial communication</li><li>Dimensions (L x W x H): 10.25 × 11 × 4 in. (256 × 275 × 100 mm)</li><li>Display Type: Fixed angle, color, touch-screen display</li><li>IP Rating: IP54 (splash and dust proof)</li><li>Licensing: Varies by region. Contact your local distributor.</li><li>Max. Power: 2W</li><li>Operating System: Ownership</li><li>Optional Accessories:&nbsp;<ul><li>Thermo Scientific™ portable test stand</li><li>Stationary (bench-top) stand</li><li>Mobile test stand</li></ul></li><li>Security Features: Password-protected user security</li><li>Standard Accessories:&nbsp;<ul><li>Locking shielded carrying case</li><li>Shielded belt holster</li><li>One 6-cell Li-ion battery pack</li><li>110/220 VAC battery charger/AC adaptor</li><li>PC connection cables (USB and RS-232)</li><li>Niton Data Transfer (NDT) PC software</li><li>Safety lanyard</li><li>Check samples/standards</li></ul></li><li>System Electronics:&nbsp;<ul><li>400 MHz ARM 11 CPU</li><li>300 MHz dedicated DSP</li><li>80 MHz ASICS DSP for signal processing</li><li>4096 channel MCA</li><li>64 MB internal system memory / 128 MB internal user storage</li></ul></li><li>Tube Type: Ag anode 38kV maximum, 80 μA maximum</li><li>Weight (English): 3 lbs 5.8 oz</li><li>Weight (Metric): 1.53 kg</li><li>Applications: Elemental Analysis</li><li>Detector Type: High-performance Semiconductor</li><li>Tube Voltage: 38 kV</li><li>Unit Size: Each</li></ul><h3>Which analyzer for your application?</h3><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg" alt="Thermo Scientific™ Niton™ handheld XRF Analyzers - Niton handheld XRF analyzers are built for rugged use and deliver rapid, lab-quality results" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg 145w," sizes="100vw" width="1024" height="1102"></div></div></div>

Thermo Scientific Niton XL2 XRF Precious Metal Analyzer

The Thermo Scientific™ Niton™ XL2 XRF Precious Metal Analyzer provides a fast, accurate, and most importantly, nondestructive method to test the purity and chemistry of all precious metals. 

<div><div><div><div><div>With the volatility and high price of gold, failing to detect just a small variation in composition can be an expensive mistake. The Thermo Scientific™ Niton™ XL2 XRF Precious Metal Analyzer provides a fast, accurate, and most importantly, nondestructive method to test the purity and chemistry of all precious metals.&nbsp;The Niton XL2 XRF Precious Metal Analyzer quickly detects gold plating and counterfeit gold and gives you the exact elemental composition of jewelry and coins so you can be absolutely certain of the value of the precious metals you buy and sell.</div><div>The Niton XL2 XRF Precious Metal Analyzer delivers accurate analysis in just seconds in an easy-to-use, robust and reliable package. Measure the content of all gold and precious metals with no need to manually change your calibration based on the metal you're analyzing—e.g., gold (Au), silver (Ag), platinum (Pt), palladium (Pd).<ul><li>Easier, faster and more accurate than nitric acid test methods.</li><li>Faster, more comprehensive analysis than fire assay with comparable accuracy.</li><li>Efficiently identify most gold-plated items with Thermo Scientific AuDIT™ gold-plating detection technology.</li><li>Precisely determine the presence and concentration of other trace alloying elements and dangerous heavy elements, which could impact valuation and future refining needs.</li></ul><h3>⚙️ Features</h3><ul><li>Standard analytical range: 22 elements from S to U (varies by application).</li><li>Point and shoot simplicity—very easy to use even by nontechnical personnel.</li><li>Ideally suited for retail environments.</li><li>Nondestructive analysis with near-instantaneous results.</li><li>Ergonomic design.</li></ul></div></div><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XL_2_XRF_Precious_Metal_Analyzer_6d4f6473b2.jpg" alt="Thermo Scientific™ Niton™ XL2 XRF Precious Metal Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XL_2_XRF_Precious_Metal_Analyzer_6d4f6473b2.jpg 144w," sizes="100vw" width="650" height="706"><h3>📏 Specifications</h3><ul><li>Applications: Non-destructive method to test the purity and chemistry of precious metals</li><li>Available Analytical Modes: Varies by application<ul><li>Alloy modes: metal alloy, electronics alloy, precious metals.&nbsp;</li><li>Bulk modes: mining, soil.&nbsp;</li><li>Plastic modes: RoHS plastics, toy and consumer goods plastics, Thermo Scientific TestAll, painted products.&nbsp;</li><li>Custom modes: upon request</li></ul></li><li>Data Memory: 64MB internal system memory / 128MB internal user storage</li><li>Data Storage: Internal &gt;10,000 readings with spectra</li><li>Data Transfer: USB, Bluetooth and RS-232 serial communication</li><li>Description: Niton XL2 XRF Precious Metal Analyzer</li><li>Detector Type: High-performance Semiconductor</li><li>Display Type: Fixed angle, color, touch-screen display</li><li>Height (English): 4 in.</li><li>Height (Metric): 100 mm</li><li>Length (English): 10.25 in.</li><li>Length (Metric): 256 mm</li><li>Width (English): 11 in.</li><li>Width (Metric): 275 mm</li><li>Optional Accessories:&nbsp;<ul><li>Portable test stand</li><li>Stationary (bench-top) stand</li><li>Mobile test stand</li><li>Welding mask</li><li>Soil testing guard</li></ul></li><li>Power Consumption: 100μA</li><li>Security Features: Password-protected user security</li><li>Standard Accessories:&nbsp;<ul><li>Locking shielded carrying case</li><li>Shielded belt holster</li><li>Two 6-cell lithium-ion battery packs</li><li>110/220VAC battery charger/AC adaptor</li><li>PC connection cables (USB and RS-232)</li><li>Thermo Scientific™ Niton Data Transfer (NDT™) PC software</li><li>Safety lanyard</li><li>Check samples/standards</li></ul></li><li>System Details:&nbsp;<ul><li>4096 channel MCA</li><li>64MB internal system memory / 128MB internal user storage</li></ul></li><li>Tube Type: Ag anode 45 kV maximum, 80μA maximum</li><li>Tube Voltage: 45 kV</li><li>Weight (English): 3.0 lb., 5.8 oz.</li><li>Weight (Metric): 1.53 kg</li><li>System Electronics:&nbsp;<ul><li>400 MHz ARM 11 CPU</li><li>300 MHz dedicated DSP</li><li>80 MHz ASICS DSP for signal processing</li></ul></li><li>Data Entry: Touch-screen keyboard, user-programmable pick lists, optional wireless remote barcode reader</li><li>Licensing: Registration: Varies by region. Contact your local distributor.</li><li>Dimensions (L × W × H): 10.25 × 11 × 4 in. (256 × 275 × 100 mm)</li><li>Operating System: Ownership</li><li>Certifications/Compliance: CE, RoHS</li><li>IP Rating: IP54 (splash and dust proof)</li><li>Max. Power: 2W</li><li>Unit Size: Each</li></ul></div></div></div>

Thermo Scientific Niton Apollo Handheld LIBS Analyzer

High-performance handheld LIBS analyzer for fast, reliable carbon analysis. Ideal for L/H grade steels and alloy verification with maximum mobility and on-site productivity.

Confidently perform elemental analysis with the Thermo Scientific™ Niton™ Apollo™ handheld LIBS analyzer. When carbon detection and mobility are top of mind, industrial businesses rely on the Niton Apollo analyzer for excellent performance and enhanced productivity.&nbsp;Identify low alloy/carbon steels and L and H grade steels. This analyzer transforms a traditional cart-mounted optical emission spectroscopy (OES) system into a highly portable, easy-to-use handheld analyzer.<div><h3>⚙️ Features &amp; Benefits</h3><ul><li>1064nm laser</li><li>WiFi enabled</li><li>Macro and micro cameras</li><li>Hot swap battery (Milwaukee Tool™ compatible)</li><li>Tilting, color touchscreen</li><li>Directional keys</li><li>Chamber pressure, spectral type, light/dark sensor safety interlocks</li><li>Password protected security</li><li>IP54 certified (splash/dust proof)</li><li>Reduced aperture &amp; compact tapered-nose design</li></ul><h3>🧪 Applications</h3><ul><li>Determine alloy composition and grade for a wide range of metallurgical samples</li><li>Calculate carbon equivalency to determine piping weldability</li><li>Verify critical assets, such as, piping, valves and reaction vessels for Positive Material Identification (PMI)</li><li>Inspect materials at receiving, in-process fabrication and outgoing Quality Control (QC)</li><li>Qualify Material Test Reports (MTR)</li><li>Prevent contaminated scrap from entering the supply stream</li><li>Detect tramp and trace elements to meet regulatory standards</li><li>Enhance productivity by measuring challenging structural shapes and sizes, including 1/4" piping, 1/4" bars, and larger weld wires</li><li>Maximize efficiency and bypass additional costs and time spent with on-site small-part measurement capabilities</li><li>Obtain unprecedented precision with a refined tapered nose and Argon seal, increasing shots per cylinder and return on investment</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_Apollo_Handheld_LIBS_Analyzer_5951f75476.jpg" alt="Thermo Scientific™ Niton™ Apollo™ Handheld LIBS Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_Apollo_Handheld_LIBS_Analyzer_5951f75476.jpg 156w," sizes="100vw" width="650" height="650"><h3>📏 Specifications</h3><ul><li>Analytical Range: C, Al, Si, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Nb, Mo, W</li><li>Argon Usage:&nbsp;<ul><li>High purity argon purge</li><li>About 200 shots per cartridge</li></ul></li><li>Available Analytical Modes: Stainless steel mode, Low alloy/carbon steel mode</li><li>Bluetooth: Bluetooth™ 4.0 (supports print functionality)</li><li>Camera:&nbsp;<ul><li>Integrated CCD macro camera for capturing overview images of parts and tagging measurement locations</li><li>Integrated CCD micro camera for locating and recording measurement positions</li></ul></li><li>Certifications/Compliance:&nbsp;<ul><li>Certifications: IP54 certified (splash and dust proof)</li><li>Compliance: CE, RoHS, FCC, Industry Canada, Safety to IEC 61010-1:2010</li></ul></li><li>Data Entry: Touchscreen keyboard User customizable data entry</li><li>Data Storage:&nbsp;<ul><li>512 MB internal system memory / 16 GB industrial grade storage</li><li>Stores approximately 5,000 readings with spectra (fewer if macro and micro images are saved)</li></ul></li><li>Data Transfer: WiFi, USB</li><li>Description: Niton Apollo Handheld LIBS Analyzer</li><li>Dimensions (L × W × H): 12 x 13 x 4 in (30.48 x 33.02 x 10.16 cm)</li><li>Display Type: Tilting, color, resistive touchscreen display</li><li>Global Positioning System: Internal GPS (ability to include coordinates with sample information)</li><li>Languages: English</li><li>Laser: 1064nm</li><li>Libraries:&nbsp;<ul><li>Default alloy libraries based on SAE, AISI, ASTM, AA, DIN, GB standards,&nbsp;</li><li>Users may create, clone and edit libraries</li></ul></li><li>Licensing: Varies by region. Contact your local distributor.</li><li>Operating Environment: Temperature: 32°F - 104°F (0°C - 40°C)</li><li>Operating System: Linux™</li><li>Optional Accessories:&nbsp;<ul><li>Thermo Scientific™ bulk argon adapter</li><li>Additional laser safety glasses</li></ul></li><li>Power Consumption: 24V, 3.75A, 90W power supply, Milwaukee Tool™ battery pack Hot swap functionality keeps analyzer powered during battery replacements</li><li>Safety Features: Chamber pressure, spectral type, light/dark sensor interlocks</li><li>Software: NitonConnect PC software</li><li>Standard Accessories:&nbsp;<ul><li>Locking shielded carrying case</li><li>Two (2) Milwaukee M18™ Redlithium™ High Demand™ CP2.0 battery packs</li><li>One (1) Milwaukee M18™ &amp; M12™ multi-voltage charger</li><li>Five (5) Thermo Scientific™ analytical argon cartridges</li><li>Setup standards</li><li>Laser safety glasses</li><li>Instrument cleaning kit</li><li>Safety lanyard and carabiner</li><li>PC connection cable</li></ul></li><li>Weight (English): 6.4 lbs with battery</li><li>Weight (Metric): 2.9 kg with battery</li><li>Applications: Identify low alloy/carbon, L grade, and H grade steels</li><li>Unit Size: Each</li></ul><blockquote><h3>Helpful links</h3><ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-xrf-analyzer-selection-guide.html">Which Niton analyzer is right for me?</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-xrf-analyzer-rental-leasing.html">Should I rent or lease this product?</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/xrf-radiation-safety-training.html">Where can I get laser safety training?</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/industrial-elemental-radiation-solutions/how-does-libs-work.html">How does LIBS work?</a></li><li>What are the applications for this handheld LIBS analyzer?<ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/positive-material-identification-oil-gas.html">Positive Material Identification</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/portable-manufacturing-metal-fabrication-analysis.html">Manufacturing and Metal Fabrication</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/portable-scrap-metal-recycling-analysis.html">Scrap Metal Recycling</a></li></ul></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/industrial-elemental-radiation-solutions/niton-apollo-handheld-libs-analyzer-faqs.html">I have additional LIBS questions, where can I learn more?</a></li></ul></blockquote></div>

Thermo Scientific ARL 9900 Total Cement Analyzer

Combines XRF and XRD in one instrument for fast and precise analysis of cement materials. One sample, one analysis – full chemical and phase information.

Achieve excellent process control and save fuel in your cement plant with both chemical and phase analysis in one simple operation. The Thermo Scientific™ ARL™ 9900 Total Cement Analyzer combines X-Ray Fluorescence (XRF) and X-Ray Diffraction (XRD) technologies for a more complete characterization of any given crystalline sample.&nbsp;Various compounds can be controlled like quartz in raw meal, hot meal, free lime in clinker, clinker phases, and additions in cement (e.g. limestone, GBFS, pozzolan) or even clinker content in cement. Clinker phase analysis ensures consistent clinker quality, which is the key to high-performance concrete.The ARL 9900 Total Cement Analyzer provides fast process monitoring during the critical phases of cement manufacturing. It combines:<ul><li>XRF analysis – determines elemental composition</li><li>XRD analysis – provides mineralogical information</li></ul>Together, they ensure the integrity of the final product.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_ARL_9900_Intelli_Power_Series_3_75f234904f.jpg" alt="Thermo Scientific™ ARL™ 9900 Total Cement Analyzer: Integration of XRF and XRD in the same instrument: one sample, one instrument, one analysis for two techniques." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_ARL_9900_Intelli_Power_Series_3_75f234904f.jpg 237w," sizes="100vw" width="1143" height="753">Traditionally, both analyses required two separate X-ray instruments, leading to higher costs. Thanks to the compact integrated XRD system, both techniques are now included in one instrument, offering key benefits:<ul><li>Only one sample introduction – fast, simple, reliable</li><li>Single user interface for both techniques</li><li>Combined elemental and phase results in one report</li><li>Minimized floor space</li><li>Replaces two instruments</li><li>Rapid and precise analysis of solid samples</li></ul>IntelliPower: choose power level as needed – 1200W, 2500W, 3600W or 4200W Advanced software: instant result reporting after analysis Easy upgrades for future analytical needs<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_ARL_9900_Total_Cement_Analyzer_8c67ede30b.jpg" alt="Thermo Scientific™ ARL™ 9900 Total Cement Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_ARL_9900_Total_Cement_Analyzer_8c67ede30b.jpg 165w," sizes="100vw" width="1626" height="1536"><h3>X-ray System</h3><ul><li>X-ray tube mounted above the sample – prevents damage (e.g. from fragile pellets)</li><li>Thermostatically regulated spectrometer – precise, sensitive, and stable measurements</li></ul><h3>Fixed Monochromators</h3><ul><li>Compact slit-crystal geometry – detects trace elements</li><li>Simultaneous multi-element analysis – for faster response</li></ul><h3>XRF Goniometers</h3><ul><li>Programmable for quantitative or qualitative element analysis</li><li>High-speed sequential X-ray spectrometry using Moire fringe technology</li><li>Handles nonroutine element analysis</li></ul><h3>Automation</h3><ul><li>Fast and reliable sample introduction, variable automation levels</li><li>Can be linked to automatic sample prep systems for online process control</li></ul>

Thermo Scientific™ ARL™ SMS-XY Automation for XRF

The Thermo Scientific™ ARL™ SMS-XY XRF system enables unattended operation, sample prep and analysis with high quality, efficiency, and reduced cost.

<div><div><h4>Increase your capacity to handle more samples in less time.&nbsp;</h4>The Thermo Scientific™ ARL™ SMS-XY Automation for XRF permits continuous and unattended operation of<a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products?instrumentationItems=100&amp;manufacturerItems=3&amp;search=9900"> Thermo Scientific™ ARL™ 9900 series X-ray Spectrometers</a>. Increased automation brings:&nbsp;<ul><li>Higher analysis quality</li><li>Lower analysis costs</li><li>Sustainable analysis cadence with predictable and reproducible response times</li><li>Short payback period</li></ul><h3>Automated Sample Handling</h3>The Thermo Scientific™ ARL™ OEM-XY automated sample loader allows connecting the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1211">ARL™ PERFORM'X</a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products?instrumentationItems=100&amp;manufacturerItems=3&amp;search=9900">ARL™ 9900</a> series to fully automatic preparation machines. Key features:<ul><li>Prepared samples (usually pressed pellets) are transported via belt conveyor from press to spectrometer</li><li>Unattended operation is ensured by engineering software supervision</li><li>Suitable for cement, metallurgy, and mining applications</li></ul></div><div><h3>Complete Automation with ARL SMS Software</h3>The ARL SMS software provides full automation of Thermo Scientific™ XRF spectrometers for routine production control, including sample preparation and analysis.<h3>Key Benefits:</h3><ul><li>Regular analysis of control samples with SPC evaluation for anomaly detection</li><li>Online connectivity for automatic sample preparation</li><li>Supports up to two sample transfer systems</li><li>Allows manual or online registration of externally prepared samples</li><li>Available as turnkey solution in ARL™ QuantoShelter cabin for production floor deployment</li><li>Seamless integration into quality control and production processes</li><li>Automatic result transmission after analysis</li></ul><h3>Compatible Sample Types:</h3><ul><li>Metallic samples (ferrous and non-ferrous)</li><li>Oxides from metal production (ores, sinters, baths, slags, blast furnace slags)</li><li>Oxides from minerals and cement</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_ARL_SMS_XY_Automation_for_XRF_2_8bce1d83a2.jpg" alt="Thermo Scientific™ ARL™ SMS-XY Automation for XRF" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_ARL_SMS_XY_Automation_for_XRF_2_8bce1d83a2.jpg 179w," sizes="100vw" width="650" height="569"></div></div>

Thermo Scientific ARL SMS-Omega XRF Instrument

Boost production efficiency with fully automated XRF analysis. The ARL OPTIM'X with SMS-Omega ensures high-quality results with unattended prep, rapid WDXRF, and compact design.

Keep up with production demands with automated XRF analysis. When different types of material have to be processed in parallel, the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1212">Thermo Scientific™ ARL OPTIM'X™ WDXRF Spectrometer</a> with the Thermo Scientific™ ARL™ SMS-Omega XRF Instrument is the solution. Automatic sample preparation and handling without user intervention, combined with rapid analysis, provide high-quality results. This innovative solution has a compact footprint of less than 1 m², so it can be installed in centralized laboratories or on production shop floors, wherever fully automated industrial production control is needed.This cost-effective system is a unique combination of Thermo Scientific XRF and automation technology for fully automated sample preparation and analysis of one material type.<h3>Main Features</h3><ul><li>Unattended instrument monitoring and integrated audit trail functions</li><li>Sample handling arm equipped with a suction device (metals version) or a gripper (oxide version) loads samples for analysis.</li><li>Samples processed under strict identical and reproducible conditions</li><li>Fixed circular magazine</li><li>XRF functionality provided by the flexible and compact <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1212">Thermo Scientific™ ARL™ OPTIM'X WDXRF </a>Instrument</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_ARL_SMS_Omega_XRF_Instrument_2_ee38dccfef.jpg" alt="Thermo Scientific™ ARL™ SMS-Omega XRF Instrument " srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_ARL_SMS_Omega_XRF_Instrument_2_ee38dccfef.jpg 233w," sizes="100vw" width="650" height="435"><h3>Features of the OPTIM'X WDXRF Instrument</h3><ul><li>WDXRF platform with sequential and/or simultaneous capabilities</li><li>Configurable to cover all elements from fluorine (F) to uranium (U) in sequential mode</li><li>Fast analysis of solids, liquids and loose powders with superior spectral resolution</li><li>No water cooling or gas supply required (depending on configuration)</li><li>Closely coupled optics for increased intensity (50% higher than conventional geometry)</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_ARL_OPTIM_X_WDXRF_Spectrometer_b264a3a303.jpg" alt="Thermo Scientific™ ARL™ OPTIM'X WDXRF Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_ARL_OPTIM_X_WDXRF_Spectrometer_b264a3a303.jpg 94w," sizes="100vw" width="650" height="1077"><h3>Features of the Fixed Circular Magazine</h3><ul><li>Eight positions for storing reference standards</li><li>Allows occasional manual introduction of prepared samples</li><li>One additional position dedicated to filing production samples following analysis</li><li>The complete system can also be supplied within a Thermo Scientific™ ARL™ QuantoShelter container for in situ analysis closer to the process.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_ARL_SMS_Omega_XRF_Instrument_87d53e64fb.jpg" alt="Thermo Scientific™ ARL™ SMS-Omega XRF Instrument" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_ARL_SMS_Omega_XRF_Instrument_87d53e64fb.jpg 216w," sizes="100vw" width="650" height="471">

Thermo Scientific ARL SMS-2300 Robotics-Based Automation for OES or XRF

Thermo Scientific™ ARL™ SMS-2300 enables fast, reproducible, and unattended OES/XRF analysis to optimize steel production and meet the strictest quality standards.

<h4>Meet stringent steel specifications while increasing efficiency and lowering production costs.</h4>The Thermo Scientific™ ARL™ SMS-2300 Robotics-Based Automation for OES or XRF is an automated quality control solution to optimize your steel production operation. With the high-performance ARL SMS-2300 system, even complex samples are prepared and analyzed under reproducible conditions without operator intervention, eliminating human variables and subjective factors. 👉 Result: Increased output, reliable results, and reduced costs.<h3>🔧 ARL SMS-2300 Automation for OES or XRF</h3>Provides ultimate power and flexibility for automatic, unattended 24/7 operation of:<ul><li>ARL™ 4460</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1213">ARL™ iSpark</a> / <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1977">iSpark Plus OES</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products?instrumentationItems=100&amp;manufacturerItems=3&amp;search=9900">ARL™ 9900 XRF</a></li></ul><h3>✅ Main Features</h3><ul><li>Easy integration into fully automatic laboratories</li><li>Installed in ARL QuantoShelter, close to production process</li><li>Parallel tasking:<ul><li>Sample preparation</li><li>Sample introduction</li><li>Analysis</li><li>Instrument stand cleaning performed in hidden time</li></ul></li><li>High throughput with:<ul><li>Automatic sample preparation</li><li>Haas Mini Mill + ARL™ PrepControl™ + EasyPrep™ software</li></ul></li><li>Direct access to Haas Mini Mill for faster ferrous sample processing</li><li>Factory-configured and customized</li><li>Compact chassis, simple installation, and integrated electronics</li><li>High reliability, rapid ROI, and fast result availability</li><li>Frees lab personnel from routine tasks</li><li>ISO 9001 compliant manufacturing and maintenance</li></ul><h3>🚀 Advanced Technology</h3><ul><li>Fanuc industrial robot</li><li>OXSAS analytical software</li></ul>

Thermo Scientific ARL SMS-3300 Automation for Single or Twin OES or XRF

Thermo Scientific™ ARL SMS-3300 enables fully automated operation of one or two OES or XRF spectrometers, enhancing lab efficiency in industrial environments.

Drive process control laboratory efficiencies in the metals, mining and cement industries with the Thermo Scientific™ ARL™ SMS-3300 Automation for Single or Twin OES or XRF, a complete laboratory workflow automation solution. The automation of single or multiple spectrometers and preparation machines with the ARL SMS-3300 system offers:👉 Reduced sample analysis cost, 👉 Increased sample throughput, 👉 Better reproducibility, and 👉 Higher quality resultsfor users requiring more comprehensive and integrated automation solutions in the metals, mining and cement industries.<h3>🔧 ARL SMS-3300 – Automation for Single or Twin OES or XRF</h3>Provides ultimate power and flexibility for automatic, unattended, 24/7 operation of:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1213">Thermo Scientific™ ARL™ iSpark </a>/<a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1977"> iSpark Plus </a>(Optical Emission Spectrometers)</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products?instrumentationItems=100&amp;manufacturerItems=3&amp;search=9900">Thermo Scientific™ ARL™ 9900</a> (X-ray Fluorescence Spectrometer)</li></ul><h3>✅ Main Features</h3><ul><li>Designed for easy integration into fully automatic laboratories</li><li>Can be mounted in Thermo Scientific ARL QuantoShelter, close to the production process</li><li>Parallel task execution:<ul><li>Sample preparation</li><li>Sample introduction</li><li>Analysis</li><li>Instrument stand cleaning performed in hidden time by the spectrometer, independently of the robot</li></ul></li><li>Direct access to milling machine for reduced processing times of ferrous samples</li><li>Higher throughput with:<ul><li>Automatic sample preparation</li><li>ARL™ PrepControl™ system + ARL™ EasyPrep™ software</li></ul></li><li>Factory configured and customized</li><li>Compact chassis and simple installation</li><li>Integrated electronics</li><li>Improved analysis reliability and quality</li><li>Very rapid payback</li><li>Faster result availability</li><li>Qualified lab personnel freed from routine tasks</li><li>Manufactured and maintained according to ISO 9001-2000 procedures</li></ul><h3>🚀 Advanced Technology</h3><ul><li>State-of-the-art Fanuc industrial robot</li><li>OXSAS analytical software</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_ARL_SMS_3300_Automation_for_Single_or_Twin_OES_or_XRF_fadcbb621a.jpg" alt="Thermo Scientific™ ARL SMS-3300 Automation for Single or Twin OES or XRF" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_ARL_SMS_3300_Automation_for_Single_or_Twin_OES_or_XRF_fadcbb621a.jpg 245w," sizes="100vw" width="650" height="366">

Thermo Scientific ARL SMS-3500 Automation for Twin OES or XRF

The ARL SMS-3500 automates two OES or XRF spectrometers with smart sample flow management for fast, efficient, and continuous production control.

Drive process control laboratory efficiencies in the metals and mining industries with the Thermo Scientific™ ARL™ SMS-3500 Automation for Twin OES or XRF, a complete laboratory workflow automation solution. Primary metals producers' laboratories typically run two fully duplicate and separate spectrometry lines to assure fast response times when several urgent samples must be processed simultaneously. 👉 The ARL SMS-3500 system is an affordable alternative.The automation of multiple spectrometers and preparation machines with the ARL SMS-3500 system offers:<ul><li>Reduced sample analysis cost</li><li>Increased sample throughput</li><li>Better reproducibility</li><li>Higher quality results</li></ul>for users requiring more comprehensive and integrated automation solutions in the metals and mining industries.The ARL SMS-3500 Automation for Twin OES or XRF simplifies sample handling by providing:<ul><li>a single introduction location for all samples</li><li>a magazine storage function to free the introduction 👉 This reduces response times, increases sample processing cadence, and improves the availability of automatic sample preparation in highly critical production control environments.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_ARL_SMS_3500_Automation_for_Twin_OES_or_XRF_2_0553f2880b.jpg" alt="Thermo Scientific™ ARL™ SMS-3500 Automation for Twin OES or XRF - 2.jpg" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_ARL_SMS_3500_Automation_for_Twin_OES_or_XRF_2_0553f2880b.jpg 217w," sizes="100vw" width="650" height="469"><h3>✅ Main Features</h3><ul><li>No need for time-consuming electro-mechanical transfer systems – the SMS-3500 robot moves samples between components within seconds</li><li>Simplified operation and reduced system complexity for easier maintenance and servicing</li><li>Single interface screen for all sample tracking and automation functions</li><li>Unified registration and introduction point for all production samples, with automated routing to the appropriate system components</li><li>Support for two sample preparation machines:<ul><li>Reduces response times</li><li>Increases processing cadence</li><li>Improves automatic sample preparation availability</li></ul></li><li>Operator workload is reduced – the system manages samples by priority and availability of resources<ul><li>Includes internal sample storage to free the introduction point immediately</li></ul></li><li>Each instrument can be used offline for manual tasks without interrupting automated operation</li><li>Uses the same analytical software for XRF and OES</li><li>Automation is based on proven ARL SMS software</li></ul><h3>🔧 Recommended for:</h3><ul><li>Iron and steel applications</li><li>High alloy, stainless steel, copper, brass, and bronze applications</li><li>Aluminum or fire assay applications</li></ul>

Thermo Scientific IonicX Portable XRF Analyzer

Thermo Scientific™ IonicX enables fast and accurate salt analysis in raw materials using portable XRF without complex preparation or destructive testing.

<div><div>Identify ionic salts in seconds with minimal sample preparation. The Thermo Scientific™ IonicX™ Portable XRF Analyzer provides:<ul><li>Fast and accurate verification of ionic salt raw materials</li><li>High sample throughput for pharmaceutical and biopharmaceutical manufacturers</li></ul>Cut testing time and costs by replacing:<ul><li>time-consuming</li><li>resource-intensive</li><li>wet chemistry and benchtop methods</li></ul>with a ✅ non-destructive, ✅ non-contact, ✅ portable XRF analyzer for ionic salts.<h3>⚙️ Key Features</h3><ul><li>Portable verification of a wide range of ionic salts in seconds</li><li>Compliant with 21 CFR Part 11:<ul><li>electronic signatures</li><li>user access control</li><li>audit trails</li></ul></li><li>Non-destructive testing of raw materials</li><li>Minimal sample preparation</li><li>Simple operation, no extensive operator training required</li><li>Lightweight and compact design for easy portability</li><li>Wi-Fi enabled</li><li>Hot Swap Battery</li><li>IP54 Certified – splash and dust proof</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Ionic_X_Portable_XRF_Analyzer_2_aa24221e46.jpg" alt="Thermo Scientific™ IonicX Portable XRF Analyzer " srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Ionic_X_Portable_XRF_Analyzer_2_aa24221e46.jpg 156w," sizes="100vw" width="650" height="650"><h3>📏&nbsp;Specifications</h3><ul><li>Bluetooth: Supports print functionality and barcode reader</li><li>Camera:<ul><li>Macro Camera: Integrated CCD macro camera for capturing overview images of parts and tagging measurement locations</li><li>Micro Camera: Integrated CCD micro camera for locating and recording measurement positions</li></ul></li><li>Certifications/Compliance:&nbsp;<ul><li>EN 55011:2010</li><li>EN 61326:2013</li><li>FCC 47 CFR Part 15</li><li>Safety EN 61010; 2010 (3rd Ed) with national deviations for US and Canada</li><li>RoHS EN 50581; 2012</li></ul></li><li>Data Entry:&nbsp;<ul><li>Touchscreen keyboard</li><li>User customizable data entry</li><li>Optional wireless remote barcode reader</li></ul></li><li>Data Storage:&nbsp;<ul><li>512 MB internal system memory/16 GB industrial grade storage</li><li>Stores approximately 130,000 readings with spectra (fewer if macro and micro images are saved)</li></ul></li><li>Data Transfer: Wi-Fi, USB</li><li>Dimensions: 12 × 12 × 8 in. (30.48 × 30.48 × 20.32 cm)</li><li>Display Type: Tilting, color, resistive touchscreen display</li><li>IP Rating: IP54 (splash and dust proof)</li><li>Languages: English</li><li>Licensing: Varies by region; Contact your local distributor</li><li>Operating Environment:&nbsp;<ul><li>Temperature: 0°C to 50°C (external fan recommended when ambient temperature is greater than 33°C)</li><li>Humidity: 10% to 90% relative humidity non-condensing</li></ul></li><li>Operating System: Linux</li><li>Optional Accessories:&nbsp;<ul><li>Thermo Scientific portable test stand</li><li>Thermo Scientific mini test stand</li></ul></li><li>Power Consumption: 12V lithium-ion battery, or 12V DC, 3A, 3.6W power supply</li><li>Security Features: Password-protected user security</li><li>Software: IonicX PC software</li><li>Spot Size: Standard: 8 mm collimation</li><li>Standard Accessories:&nbsp;<ul><li>Locking shielded carrying case</li><li>Two (2) lithium-ion battery packs</li><li>One (1) 110/220 VAC battery charger/AC adaptor</li><li>Check samples</li><li>Safety lanyard</li><li>PC connection cable (USB)</li></ul></li><li>System Details: Built-in standardization via automatic system check</li><li>Weight (English): 5.8 lbs. with battery and test stand</li><li>Weight (Metric): 2.6 kg with battery and test stand</li><li>X-Ray Source Type:&nbsp;<ul><li>X-Ray Tube: Ag anode (6–50 kV, 0–500 μA, 5W max)</li><li>Dynamically adjustable current for optimal sensitivity on every analysis</li></ul></li><li>Applications: Raw Material Testing</li><li>Detector Type: Proprietary Large Area Drift Detector</li><li>Tube Voltage: 6 to 50 kV</li><li>Unit Size: Each</li></ul></div></div>

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