<div><div><p><strong>Researchers led by </strong><a target="_blank" rel="noopener noreferrer" href="https://kudova.group.uochb.cz/en"><strong>Eva Kudová</strong></a><strong> from IOCB Prague and Jitka Viktorová from UCT Prague have identified new androstane-based steroid derivatives that can significantly improve the effectiveness of existing antibiotics against multidrug-resistant </strong><i><strong>Staphylococcus aureus</strong></i><strong>.</strong></p></div></div><div><p>The team screened dozens of natural steroidal hormones and synthetic derivatives to see whether they could block bacterial efflux pumps – mechanisms that bacteria use to eject antibiotics and survive treatment. Two compounds emerged as particularly promising: they inhibited efflux pumps and lowered the effective doses of antibiotics such as ciprofloxacin and erythromycin.</p><p>Further analysis showed that one of the compounds also suppressed genes linked to bacterial virulence. Another key finding is that the most active molecules are non-toxic to human immune cells and showed no detectable endocrine activity, suggesting a favorable safety profile.</p><p>These findings support the idea that rationally designed steroid-based molecules could act as antibiotic adjuvants, helping existing drugs overcome bacterial resistance.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/IOCB_Prague_Steroidal_hormones_and_neurosteroids_novel_therapeutic_strategies_in_bacterial_infections_8e5d2a7b48.jpg" alt="IOCB Prague: Steroidal hormones and neurosteroids – novel therapeutic strategies in bacterial infections" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_IOCB_Prague_Steroidal_hormones_and_neurosteroids_novel_therapeutic_strategies_in_bacterial_infections_8e5d2a7b48.jpg 222w," sizes="100vw" width="1258" height="886"></p><blockquote><h4><strong>Original Article</strong></h4><h4><a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S0223523426001613?via%3Dihub"><strong>Steroidal hormones and neurosteroids - novel therapeutic strategies in bacterial infections: Design, synthesis, and biological evaluation</strong></a></h4><p>Daniela Brdová, Bára Křížkovská, Jan Špaček, Zdeněk Míchal, Eva Jablonská, Ondřej Strnad, Hana Chodounská, Eszter Szánti-Pintér, Marina Morozovová, Václav Hanžl, Jan Tkadlec, Martijn Riool, Jan Lipov, Jitka Viktorová, Eva Kudová&nbsp;</p><p><i><strong>Eur. J. Med. Chem., 2026, 308, 118716</strong></i></p><p><a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1016/j.ejmech.2026.118716">https://doi.org/10.1016/j.ejmech.2026.118716</a></p><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/"><strong>CC-BY 4.0</strong></a></h6></blockquote><h4><strong>Abstract</strong></h4><p>The global rise of antibiotic resistance necessitates novel therapeutic strategies for infectious diseases. Inhibition of bacterial efflux pumps, which contribute to multidrug resistance, represents a promising approach to restore or even increase the efficacy of existing antibiotics. Using fluorescence-based ethidium bromide accumulation, broth microdilution, and checkerboard assays, we evaluated 26 endogenous steroidal hormones and neurosteroids, along with 30 synthetic derivatives, for their ability to enhance antibiotic susceptibility in multidrug-resistant <i>Staphylococcus aureus</i>. Structure-activity relationship analysis identified compounds <strong>13</strong> and <strong>16</strong> as lead candidates, exhibiting strong efflux pump inhibition and marked reductions in the minimum inhibitory concentrations of ciprofloxacin and erythromycin. Both compounds showed additive effects in checkerboard assays. Modifications at C-3 (polar substitution) and C-17 (3α,5β-stereochemistry and nonpolar substitution) were essential for potent efflux inhibition and sensitization, although these modifications were not additive when combined. Transcriptome analysis further revealed that compound <strong>13</strong> significantly downregulated <i>S. aureus</i> virulence-associated genes when administered alone or in combination with antibiotics. Cytotoxicity assessment in human peripheral blood mononuclear cells and receptor transactivation assays for estrogen, androgen, and progesterone receptors indicated that the most active derivatives were non-toxic and lacked detectable endocrine activity, suggesting a favorable safety profile. Overall, these findings support the concept that rationally designed andostane-based steroidal scaffolds can function as competitive bacterial efflux pump inhibitors and serve as potential antibiotic adjuvants to mitigate efflux-mediated resistance.</p><h4><strong>Instrumentation</strong></h4><h5><strong>Structural characterization</strong></h5><ul><li><strong>AVANCE III 400 MHz NMR spectrometer</strong> (Bruker)</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?mainauthorItems=3&amp;search=LTQ+Orbitrap+XL"><strong>LTQ Orbitrap XL HRMS</strong></a> (Thermo Fisher Scientific, ESI)</li></ul></div>

Steroidal hormones and neurosteroids – novel therapeutic strategies in bacterial infections

<p><strong>Wiley, a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation and learning, today announced the release of additional data to its IR and Raman spectral libraries, significantly broadening compound coverage, including materials, polymers, minerals, and others.</strong></p><p>This latest release includes the first installment of Raman spectra from <strong>Wiley's collaboration with the American Museum of Natural History (AMNH), announced earlier this spring</strong>, drawing from one of the world's most important mineral collections.</p><p>“<i>Researchers depend on reference data as a foundation for sound scientific decisions</i>,” said Graeme Whitley, senior director, data science solutions at Wiley. “<i>Continuous updates ensure scientists always have the most current, reliable reference libraries at their fingertips, helping them work faster and make confident decisions when it matters most.</i>”</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_Wiley_expands_its_trusted_IR_and_Raman_spectral_library_collections_helping_analytical_labs_make_faster_more_confident_decisions_1a54aaad3a.jpg" alt="Wiley: Wiley expands its trusted IR and Raman spectral library collections—helping analytical labs make faster, more confident decisions" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Wiley_Wiley_expands_its_trusted_IR_and_Raman_spectral_library_collections_helping_analytical_labs_make_faster_more_confident_decisions_1a54aaad3a.jpg 245w," sizes="100vw" width="1600" height="856"></p><h4><strong>Summary of updates:</strong></h4><h5><strong>KnowItAll Raman Spectral Library Collection</strong></h5><ul><li><strong>Added: </strong>1,213 spectra</li><li><strong>Now contains: </strong>29K+ spectra</li></ul><p><strong>2 new databases:</strong></p><ul><li>Raman – American Museum of Natural History Minerals – Wiley – 198 spectra</li><li>Raman – Microbiology – 71 spectra</li></ul><p><strong>Spectra added to databases:</strong></p><ul><li>Raman – Consumer Goods &amp; Food-Related Compounds – +104</li><li>Raman – Drugs – +128</li><li>Raman – Materials – +132</li><li>Raman – Minerals – +233</li><li>Raman – Polymers – +5</li><li>Raman – Pigments &amp; Dyes – +342</li></ul><h5><strong>KnowItAll IR Spectral Library Collection</strong></h5><ul><li><strong>Added: </strong>949 spectra</li><li><strong>Now contains: </strong>344K+ spectra</li></ul><p><strong>7 new databases:</strong></p><ul><li>ATR-IR – Clinical – 364 spectra</li><li>ATR-IR – Materials – 10 spectra</li><li>ATR-IR – Pigments &amp; Dyes – 420 spectra</li><li>ATR-IR – Polymers – 21 spectra</li><li>IR – Clinical – 20 spectra</li><li>IR – Materials – 17 spectra</li><li>IR – Microbiology – 75 spectra</li></ul><p><strong>Spectra added to databases:</strong></p><ul><li>IR – Minerals – +5</li><li>IR – Polymers – +17</li></ul><p>Spectral library subscribers automatically gain access to new data, ensuring labs always have the most current, reliable reference libraries to improve analysis, reduce errors, and increase productivity.</p><ul><li>Learn more at: <a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/spectral-databases/"><strong>www.sciencesolutions.wiley.com/spectral-databases</strong></a></li><li>Existing subscribers can access step-by-step guidance on updating their KnowItAll databases at <a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/how-to-update-knowitall-databases"><strong>https://sciencesolutions.wiley.com/how-to-update-knowitall-databases</strong></a></li></ul><h5><strong>Wiley Spectral Databases</strong></h5><p>Wiley's spectral databases are consistently evolving to meet today's research demands, covering multiple spectral techniques across a wide range of applications including polymers, materials, environmental, forensics, toxicology, pharmaceutical, biotech, automotive, aerospace, food, cosmetics, and more. Built on rigorous quality protocols, Wiley delivers industry-leading spectral data and intelligent tools to accelerate analysis and deliver deeper insights — making it the authoritative, trusted source that analytical labs worldwide rely on.&nbsp;</p><h5><strong>About Wiley</strong></h5><p>Wiley (NYSE: WLY) is a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation, and learning. With more than 200 years at the center of the scholarly ecosystem, Wiley combines trusted publishing heritage with AI-powered platforms to transform how knowledge is discovered, accessed, and applied. From individual researchers and students to Fortune 500 R&amp;D teams, Wiley enables the transformation of scientific breakthroughs into real-world impact. From knowledge to impact—Wiley is redefining what's possible in science and learning.&nbsp;</p>

Wiley expands its trusted IR and Raman spectral library collections

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 4th May 2026? Check out new documents from the field of spectroscopy/spectrometry and related techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><strong>LabRulezGCMS</strong></a> libraries.</p></blockquote><p>This week we bring you application notes by<strong> KNAUER, Shimadzu, </strong>and <strong>Thermo Fisher Scientific!</strong></p><h3><strong>1. KNAUER: Analysis of HPLC fractions by Benchtop NMR</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/knauer_hplc_benchtop_nmr_web_638c60e13c.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Preparative HPLC is essential for isolating compounds and removing impurities in pharmaceutical and chemical industries. Non-destructive, fast analysis is preferred to maintain yield and enable at-line monitoring, avoiding lengthy sample preparation. Recent advancements in benchtop NMR spectrometers (up to 90 MHz) allow quick analysis without deuterated solvents. In this proof-of-concept study we purified a pharmaceutical sample via HPLC and confirmed its identity using benchtop NMR. Fractions (0.7–4.4 mM) were analyzed without preparation, using only 300 µL per sample, ensuring rapid batch control with no product loss. This study demonstrates the seamless integration of HPLC and benchtop NMR.</p><h4><strong>Experimental</strong></h4><h5><strong>Preparative HPLC Method</strong></h5><p>Eluent 20:80 Ethanol/water, isocratic mode, flow rate 12.5 ml/min, detection UV254 nm 2 Hz, 500 µl stacked injection, automated fractionation with threshold function, column temperature ambient, Column Eurospher II 100-10 C18 150x20 mm&nbsp;</p><h5><strong>Analytical HPLC Method</strong></h5><p>Eluent 20:80 Ethanol /water + 0.1% formic acid, isocratic mode, flow rate 1 ml/min, detection UV254 nm 10 Hz, 5 µl partial loop injection, column temperature 25 °C, Column <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1633"><strong>Eurospher II 100-5 C18</strong></a> 150x4 mm&nbsp;</p><h5><strong>NMR Method&nbsp;</strong></h5><p>NMR spectra were acquired on a <strong>Magritek Multi-X Ultra 80 MHz benchtop NMR system</strong> using an adapted WET sequence for solvent suppression. 32 scans were acquired with a repetition time of 15s. WET parameters were adjusted for each sample to yield optimal suppression for all solvent signals. Pooled HPLC fractions were analysed directly without addition of deuterated solvents or other sample preparation.</p><h4><strong>Conclusion</strong></h4><p>This proof-of-concept study successfully shows that HPLC and benchtop NMR can be used together easily. Samples can be analyzed non-destructively within minutes and without any further preparation due to highly efficient suppression of multiple solvent signals. Compounds can be identified without the need of reference standards. This study shows that NMR can provide a valid compatible alternative detector for HPLC fraction analysis.</p><h3><strong>2. Shimadzu: DIC Analysis in High-Speed Tensile Test of CFRP</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_00854_en_fb6c68b858.pdf"><strong>Full PDF for download</strong></a></li></ul><h4><strong>User Benefits</strong></h4><ul><li>The <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=1&amp;search=HPV-X3"><strong>HPV-X3</strong></a> is suitable for observation of fracture of brittle materials such as CFRP because it has a maximum recording speed (framerate) of 20 Mfps.&nbsp;</li><li>The HPV-X3 provides improved DIC analysis performance, as its resolution is 3 times higher than that of the conventional highspeed video camera.</li><li>The HITS-TX impact testing machine enables testing at a maximum speed of 20 m/s</li></ul><p>Carbon fiber reinforced plastic (CFRP) is a material with particularly high specific strength, even among composite materials, and used in various applications such as transport aircraft, taking advantage of its excellent mechanical properties. Because CFRP consists of carbon fibers and resin, it shows complex fracture behavior, and brittle fracture progresses from damage as the point of origin. Since fracture proceeds instantaneously, a high-speed video camera with a high recording speed is necessary when observing fracture of CFRP. One method for measuring strain in a high-speed tensile test is Digital Image Correlation (DIC), which visualizes the distribution of strain at the specimen surface by comparing a random pattern on the specimen surface before and after deformation. Thus, a high-speed video camera with a high resolution is also necessary in order to improve the DIC performance.&nbsp;</p><p>Newly-developed <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=1&amp;search=HPV-X3"><strong>Hyper Vision HPV-X3 high-speed video camera</strong></a> is extremely well-suited to DIC analysis of CFRP, as its recording speed is 2 timesfaster and itsresolution is 3 times higher than the conventional HPV-X2. In this experiment, a high-speed tensile test of CFRP was conducted using a HITS-TX high-speed tensile testing machine. The condition of the test was observed with the new HPV-X3, and the strain distribution of the CFRP test piece was clarified by a DIC analysis of the recorded images.</p><h4><strong>Test Piece and Test Instruments</strong></h4><p>A CFRP quasi-isotropic laminate was used as the test piece. Aluminum foil was glued to the back side of the test piece, and the timing when the electrical conduction of the aluminum foil was interrupted by fracture of the test piece was used as the trigger for video recording. The HITS-TX was used in the highspeed tensile test. The HPV-X3 was used in fracture observation, and for comparison, the fracture process was also recorded with the conventional HPV-X2 camera. Fig. 1 shows the condition of the test, and Table 1 and Table 2 show the equipment composition and test conditions, respectively.</p><h4><strong>DIC Analysis Results in High-Speed Tensile Test</strong></h4><p>Fig. 3 shows the DIC analysis results in the high-speed tensile test. The color bar was set to display the color purple at around 0 % strain and red at around 2 % strain. Fig. 3 (1) is an image at the start of the test. After the test started, strain in the 45˚ direction concentrated from the lower left to the right central area, as can be seen in Fig. 3 (2). Then, as the test progressed, a condition of increasing strain in the initial area of strain concentration can be seen in Fig. 3 (3) to (9). A crack occurs in Fig. 3 (10), and strain decreases in the crack area. Following this, the test piece fractured completely in Fig. 3 (11) and (12), and a decrease in the strain in the area around the crack could be observed.</p><h4><strong>Conclusion</strong></h4><p>A high-speed tensile test of CFRP was conducted using a HITSTX high-speed tensile testing machine and the newlydeveloped HPV-X3 high-speed video camera, and the strain distribution at the time of test piece fracture was visualized by a DIC analysis. Because the HPV-X3 offers a 3 times higher resolution and a 2 times faster recording speed than the conventional device, it is a suitable high-speed video camera for fracture observation and DIC analysis in impact tests of brittle materials such as CFRP. The measurement system introduced in this Application News article is a useful tool for the development of composite materials.</p><h3><strong>3. Thermo Fisher Scientific: Polymer analysis using femtosecond-laser-ablation depth profiling</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/xps_depth_profiling_polymer_analysis_appnote_c731e2e7e0.pdf"><strong>Full PDF for download</strong></a></li></ul><p>X-ray photoelectron spectroscopy (XPS) is an essential polymer characterization technique that can identify not just the elemental composition but also the chemical state of polymer samples. This allows the chemical bonding environment to be deduced and, as a result, the polymer species can be identified. This can all be achieved with minimal sample preparation thanks to the built-in charge-compensation systems found in XPS instruments, which simplify the analysis of insulating samples.&nbsp;</p><p>The introduction of gas cluster ion sources (GCIS), such as the Thermo Scientific™ MAGCIS Dual Mode Ion Source, marked a major step forward in polymer analysis. Unlike monatomic ion beams, GCIS are able to clean surface contamination, and etch away layers of sample material, without damaging the underlying chemistry of organic samples such as polymers. As a result, GCIS has allowed chemical-damage-free analysis to reach micrometers below the sample surface. This depth of analysis can be highly time consuming, however, and total experimental times can range from multiple hours to days.&nbsp;</p><p>The addition of femtosecond-laser-ablation (fs-LA) technology is alleviating this, allowing for XPS spectra to be collected from a depth of tens of µm into a sample in a matter of minutes. This is because the laser ablation occurs on the femtosecond timescale (i.e., nearly instantaneously), effectively eliminating the material removal time of the depth profile. Additionally, unlike other material removal techniques such as atomic ion beam impact (where a collision cascade effect is induced to remove surface material) fs-LA is capable of removing material without chemical damage due to the ultrashort columbic explosion process used to eject the material. The resulting profile is therefore representative of the actual sample chemistry.</p><h4><strong>Paint layer analysis&nbsp;</strong></h4><p>In traditional ion-beam depth profiling, analytical depths are generally limited to several hundred nanometers, up to a micrometer. This means that it is extremely difficult to analyze the interfaces between multiple micrometer-thick layers in a sample without the use of additional techniques such as ultralow-angle microtome (ULAM) sectioning.¹ The introduction of fs-LA technology, however, allows micrometers of material to be removed rapidly, enabling the characterization of layered samples.&nbsp;</p><p>As an example, a multi-layer paint specimen (provided by the University of Surrey, UK) was depth profiled using the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2206"><strong>Thermo Scientific™ Hypulse™ Surface Analysis System</strong></a>. The sample consists of an aluminum substrate coated with a 5 µm layer of polyurethane primer followed by a 25 µm PMMA/PVdF topcoat.</p><p>The depth profile was generated using a 1,030 nm laser with an energy of 250 µJ for ablation, along with a 30 µm X-ray spot size for data collection. XPS spectra were collected after each ablation cycle to obtain an atomic concentration plot through both paint layers into the substrate material (Figure 2).&nbsp;</p><p>5 distinct regions throughout the analyzed depth can be seen. The top surface of the sample consists of an adventitious layer of carbon contamination, which is commonly found on samples exposed to air. The second layer is the 25 µm PVdF/PMMA topcoat, and the third layer is the PU primer. Between the primer and the final aluminum substrate layer, a clear increase in adventitious carbon is observed, similar to the signal seen at the top sample surface. This suggests residual carbon contamination was present on the substrate before the paint layers were applied.&nbsp;</p><p>It would take hours to produce the XPS depth profile shown in Figure 2 using traditional ion beam approaches. Even with the use of a monatomic beam with a high energy per atom, the length of the analysis could still be just as long, depending on the sample material, and would sacrifice the chemistry of any organic/polymeric materials. The combination of fs-LA depth profiling and snapshot XPS acquisition, meanwhile, can reduce the experimental time to less than 20 minutes without inducing any chemical damage to the sample surface.</p><h4><strong>Summary&nbsp;</strong></h4><p>One of the most critical aspects of successful polymer XPS depth profiling is the preservation of the sample chemistry during material removal. Additionally, experiment time can be a significant limiting factor, and thicker samples could lead to reduced time for repeat experiments. The femtosecond laser ablation capabilities of the Hypulse Surface Analysis System provide fast, efficient, and chemical-damage-free material removal from a sample surface, enabling analysis multiple micrometers into a sample. This means that hidden sample interfaces, that were largely inaccessible before, can now be analyzed easily and efficiently</p>

News from LabRulezICPMS Library - Week 19, 2026

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The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) is a leading scientific institution in the Czech Republic, recognized internationally. Its primary mission is basic research in the fields of chemical biology and medicinal chemistry, organic and material oriented chemistry, chemistry of natural compounds, biochemistry and molecular biology, physical chemistry, theoretical chemistry, and analytical chemistry. 

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

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Wiley

Thermo Scientific ARL PERFORM'X Sequential X-Ray Fluorescence Spectrometer

Solve analytical challenges in a wide range of applications with X-ray fluorescence with sample surface mapping and small spot analysis with Thermo Scientific ARL PERFORM'X Sequential X-Ray Fluorescence Spectrometer

<p><strong>Solve analytical challenges in a wide range of applications with one comprehensive tool. The Thermo Scientific™ ARL™ PERFORM'X Sequential X-Ray Fluorescence Spectrometer for advanced materials characterization integrates bulk elemental analysis with mapping and small spot analysis to create a solution that evaluates up to 90 elements in nearly any solid or liquid sample.</strong></p><p>Industries as diverse as metallurgy, petroleum, polymers, mining, glass, cement and refractories as well as labs dealing with geochemistry, materials science, environmental research and forensics will benefit from its performance and versatility.</p><p>With the ARL PERFORM'X spectrometer, analysis of materials in varied sizes, coatings, layers, heterogeneities and inclusions or requiring wide elemental coverage, wide concentration ranges and varied samples matrices is achieved with desired precision and limits of detection.</p><h5><strong>Advanced Technology</strong></h5><ul><li>Digitally mastered gearless goniometer based on Moiré fringe electro-optical technology, for precise and robust angular positioning of all its components.</li><li>Powerful OXSAS software and standard-less Thermo Scientific™ <strong>QuantAS™</strong> and Thermo Scientific™ <strong>UniQuant™ Analysis Packages </strong>provide simple and rapid analysis of totally unknown samples with no standards required.</li><li>Thermo Scientific™ <strong>PetroilQuant™ Pre-calibration program</strong>, capable of quantifying up to 30 elements in a variety of fuels, light and heavy distillates and lubricants both quickly and cost-effectively.</li><li>UCCO technology: Ultra Closely Coupled Optics for highest performance from boron to uranium.</li><li>IQ/OQ &amp; Remote Diagnostics for easy installation and serviceability.</li></ul><h5><strong>Main Features</strong></h5><ul><li>Large library of factory calibrations covering many metals and non-metals applications.</li><li>Material composition mapping and quantification capability.</li><li>Small spot analysis for contamination or defect identification and quantification.</li><li>Industry-leading liquid sample recognition and leak prevention design.</li><li>Wide dynamic range (from sub ppm to 100%) and excellent precision.</li><li>Integrated comprehensive sample changer allows large numbers of different samples to be treated fully automatically in mixed batches.</li><li>Faster analysis cycle time for high throughput lab applications using XY-loader for fully automated sample management.</li><li>Easy, non-destructive sample preparation.</li></ul><h5><strong>Models</strong></h5><ul><li><strong>ARL PERFORM'X 1500W</strong>: Cost effective low-power system, no external water cooling required.</li><li><strong>ARL PERFORM'X 2500</strong>W: High performance mid-power system, no external water cooling required.</li><li><strong>ARL PERFORM'X 4200W</strong>: Highest power system for the most demanding applications.</li></ul><h5><strong>Recommended for</strong></h5><ul><li>Geological and environmental applications.</li><li>Petroleum products, polymers and chemicals.</li><li>Materials science and forensics.</li><li>Major, minor and trace elemental analysis in raw materials, glasses, ceramics and refractories.</li><li>Specialty alloys, metals and ores.</li><li>Mining, minerals and cement.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_ARL_PERFORM_X_Sequential_X_Ray_Fluorescence_Spectrometer_5_6bac427b14.jpg" alt="Thermo Scientific: ARL PERFORM'X Sequential X-Ray Fluorescence Spectrometer - Application" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_ARL_PERFORM_X_Sequential_X_Ray_Fluorescence_Spectrometer_5_6bac427b14.jpg 198w," sizes="100vw" width="547" height="432"></p>

Thermo Scientific Niton XL5 Plus Handheld XRF Analyzer

Confidently perform elemental analysis with the Thermo Scientific™ Niton™ XL5 Plus handheld XRF analyzer; it delivers unprecedented performance even for lightweight elements.

<p><strong>Confidently perform elemental analysis with the Thermo Scientific™ Niton™ XL5 Plus handheld XRF analyzer; it delivers unprecedented performance even for lightweight elements. Identify pure metals and alloys, detect tramp elements, or obtain geochemical data.&nbsp;</strong></p><p>Industrial businesses rely on the Niton XL5 Plus analyzer for more than just low detection limits. It generates fast results and offers great versatility such as the ability to scan a broad range of materials with a single analyzer.</p><p>More than <strong>75,000 Niton handheld XRF analyzers</strong> have been deployed worldwide since 1994, making them the trusted standard for in-field elemental analysis.</p><div><h3><strong>⚙️ Features</strong></h3><ul><li>5W X-ray tube</li><li>Proprietary large area drift detector for light element detection (Mg, Al, Si, P, S)</li><li>Lightweight design (2.8 lbs/ 1.3 kg)</li><li>Miniaturized nose</li><li>WiFi enabled</li><li>Macro and micro cameras</li><li>Hot swap battery</li><li>Tilting, color touchscreen</li><li>Directional keys</li><li>Password protected security</li><li>IP54 certified (splash/dust proof)</li></ul><h3><strong>🧪 Applications</strong></h3><ul><li>Verification of metals and alloys in manufacturing operations</li><li>Non-destructive field inspections for positive material identification</li><li>Point-and-shoot sorting at scrap recycling operations</li><li>Coating thickness measurements for single or binary metal layers</li><li>Precious metal assay of bullion and jewelry</li><li>Real-time geochemical analysis for mining exploration</li><li>On-site heavy metal screening of polluted soils</li><li>Screening of hazardous substances in consumer goods</li><li>Custom applications on demand</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XL_5_Plus_Handheld_XRF_Analyzer_2_2967c6cd9a.jpg" alt="Thermo Scientific™ Niton™ XL5 Plus Handheld XRF Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XL_5_Plus_Handheld_XRF_Analyzer_2_2967c6cd9a.jpg 156w," sizes="100vw" width="650" height="650"></p><h3><strong>📏 Specifications</strong></h3><ul><li><strong>Certifications/Compliance:</strong> CE, RoHS, FCC, Industry Canada, Safety to IEC 61010-1:2010</li><li><strong>Data Entry:</strong><ul><li>Touchscreen keyboard</li><li>User customizable data entry</li><li>Optional wireless remote barcode reader</li></ul></li><li><strong>Data Storage:</strong> 512 MB internal system memory / 16 GB industrial grade storage; Stores approximately 130,000 readings with spectra (fewer if macro and micro images are saved)</li><li><strong>Data Transfer:</strong> WiFi, USB-c</li><li><strong>Dimensions (L × W × H):</strong> 9.54 × 8.19 × 2.67 in. (24.23 × 20.8 × 6.78 cm)</li><li><strong>Display Type:</strong> Tilting, color, resistive touchscreen display</li><li><strong>Global Positioning System:</strong> Internal GPS and optional external GPS (via Bluetooth); GPS data are included with the sample information.<br>NOTE: The GPS function is an optional feature.</li><li><strong>Languages:</strong> English, Chinese, Spanish, Portuguese, Russian, Japanese, German, Korean, French, Turkish, Italian</li><li><strong>Libraries:</strong> Default alloy libraries based on SAE, AISI, ASTM, AA, DIN, GB standards. Users may create, clone and edit libraries.</li><li><strong>Licensing:</strong> Varies by region. Contact your local distributor.</li><li><strong>Operating Environment:</strong><ul><li><strong>Temperature:</strong> 0°C to 50°C (external fan recommended when ambient temperature is greater than 33°C)</li><li><strong>Humidity:</strong> 10% to 90% relative humidity non-condensing</li></ul></li><li><strong>Operating System:</strong> Linux</li><li><strong>Optional Accessories:</strong><ul><li>Portable test stand</li><li>Mini test stand</li><li>Desk/wall holder</li><li>Hotwork stand off</li><li>Soil guard</li><li>Belt holster</li><li>Bluetooth printer</li></ul></li><li><strong>Power Consumption:</strong> 12V lithium-ion battery, or 12V DC, 3A, 3.6W power supply. Hot swap functionality keeps analyzer powered during battery replacements.</li><li><strong>Security Features:</strong> Password-protected user security</li><li><strong>Software:</strong> Support software: NitonConnect PC software</li><li><strong>Spot Size:</strong><ul><li><strong>Standard: </strong>8mm collimation</li><li><strong>Optional:</strong> 3mm small-spot collimation</li></ul></li><li><strong>Standard Accessories:</strong><ul><li>Locking shielded carrying case</li><li>Two (2) lithium-ion battery packs</li><li>One (1) 110/220 VAC battery charger/AC adapter</li><li>Check samples</li><li>Safety lanyard</li><li>PC connection cable (USB)</li></ul></li><li><strong>System Details:</strong> Built-in standardization and health check verify system integrity and operating conditions</li><li><strong>Type:</strong> XL5 Plus Handheld XRF Analyzer</li><li><strong>Weight (English):</strong> 2.8 lb. with battery</li><li><strong>Weight (Metric):</strong> 1.3 kg with battery</li><li><strong>X-Ray Source Type:</strong><ul><li><strong>X-ray tube: </strong>Ag anode (6–50kV, 0–500µA, 5W max)</li><li><strong>Filter: </strong>Six (6) position filter wheel for enhanced spectral range coverage</li><li><strong>Current: </strong>Dynamically adjustable current for optimal sensitivity on every analysis</li></ul></li><li><strong>Detector Type:</strong> High count rate, high resolution, extra large area silicon drift detector (11µm graphene window). Detector ProGuard protection included.</li><li><strong>Unit Size:</strong> Each</li></ul><h3><strong>Which analyzer for your application?</strong></h3><figure class="image"><img style="aspect-ratio:1024/1102;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg" alt="Thermo Scientific™ Niton™ handheld XRF Analyzers - Niton handheld XRF analyzers are built for rugged use and deliver rapid, lab-quality results" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg 145w," sizes="100vw" width="1024" height="1102"></figure><blockquote><h3><strong>Helpful links</strong></h3><ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-xrf-analyzer-selection-guide.html">Which XRF analyzer is right for me?</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-xrf-analyzer-rental-leasing.html">Should I rent or lease this product?</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/xrf-radiation-safety-training.html">Where can I get radiation safety training?</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/spectroscopy-elemental-isotope-analysis-learning-center/elemental-analysis-information/xrf-technology.html">What is XRF Technology?</a></li><li>What are the applications for this handheld XRF analyzer?<ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/portable-scrap-metal-recycling-analysis.html">Scrap Metal Recycling</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/portable-manufacturing-metal-fabrication-analysis.html">Manufacturing and Metal Fabrication</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/positive-material-identification-oil-gas.html">Positive Material Identification</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-mining-exploration-solutions.html">Mining and Exploration</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/portable-precious-metals-jewelry-analysis.html">Precious Metals</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-consumer-safety-regulatory-solutions.html">Consumer Safety &amp; Regulatory</a></li></ul></li></ul></blockquote></div>

Thermo Scientific Niton XL2 Plus Handheld XRF Analyzer

Obtain fast, accurate elemental analysis for metal and alloy identification, PMI testing and more with the Niton™ XL2 Plus Handheld XRF Analyzer.

<div><p><strong>Confidently perform elemental analysis with the Thermo Scientific™ Niton™ XL2 Plus handheld XRF analyzer. When durability, performance and productivity are top of mind, industrial businesses rely on the Niton XL2 Plus handheld XRF analyzer for fast results and low detection limits.&nbsp;</strong></p><p>Identify pure metals and alloys, or obtain geochemical data, the Niton XL2 Plus provides operators the ability to scan a broad range of materials in one versatile analyzer.</p></div><p>More than <strong>75,000 Niton handheld XRF analyzers</strong> have been deployed worldwide since 1994, making them the trusted standard for in-field elemental analysis.</p><div><h3><strong>⚙️ Features &amp; Benefits</strong></h3><ul><li>2W X-Ray Tube</li><li>Silicon Drift Detector (SDD) for light element detection (Mg, Al, Si, P, S)</li><li>Detector ProGuard Protection</li><li>Micro Camera</li><li>Hot Swap Battery</li><li>Touch Screen and Directional Keys</li><li>Password Protected Security</li><li>IP54 Certified (Splash/ Dust Proof)</li><li>Nose Cone Alignment Guides</li></ul><h3><strong>🧪 Applications</strong></h3><ul><li>Verification of metals and alloys in manufacturing</li><li>Quality Assurance testing for positive material identification</li><li>Point-and-shoot sorting at scrap recycling operations</li><li>Coating thickness measurements from single element layers</li><li>Precious metal assay of bullion and jewelry</li><li>Geochemical analysis for ore trading and grade control</li><li>On-site heavy metal screening of polluted soils</li><li>Lead in paint inspection of industrial facilities</li><li>Screening of hazardous substances in consumer goods</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XL_2_Plus_Handheld_XRF_Analyzer_3_cb63ae77a5.jpg" alt="Thermo Scientific™ Niton™ XL2 Plus Handheld XRF Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XL_2_Plus_Handheld_XRF_Analyzer_3_cb63ae77a5.jpg 156w," sizes="100vw" width="650" height="650"></p><h3><strong>📏 Specifications</strong></h3><ul><li><strong>Analytical Range:</strong> Mg–U</li><li><strong>Available Analytical Modes:</strong> General Metals, Precious Metals, Coatings, Mining, Soils, Electronic Alloys, Plastics, Industrial Lead in Paint, Lead in Paint Products</li><li><strong>Bluetooth:</strong> Supports print functionality, external GPS connectivity and barcode reader</li><li><strong>Camera:</strong> Integrated CCD micro camera for locating and recording measurement positions</li><li><strong>Certifications/Compliance:</strong> CE, RoHS, FCC, Industry Canada, Safety to IEC 61010-1, UL 61010-1, IP54 (splash and dust proof)</li><li><strong>Data Entry:</strong>&nbsp;<ul><li>Touchscreen keyboard</li><li>User customizable data entry</li><li>Optional wireless remote barcode reader</li></ul></li><li><strong>Data Storage:</strong><ul><li>64 MB internal system memory / 128 MB internal user storage</li><li>Stores approximately 10,000 readings with spectra (fewer if images are saved)</li></ul></li><li><strong>Data Transfer:</strong> USB, Bluetooth, RS-232 serial communication</li><li><strong>Description:</strong> Niton XL2 Plus Handheld XRF Analyzer</li><li><strong>Dimensions (L × W × H):</strong> 10 × 10.8 × 3.9 in (25.6 × 27.5 × 10 cm)</li><li><strong>Display Type:</strong> Fixed angle, color, resistive touchscreen display</li><li><strong>Global Positioning System:</strong> Optional external GPS (via Bluetooth)</li><li><strong>Languages:</strong> English, Chinese, Spanish, Portuguese, Russian, Japanese, German, Korean, French, Italian, Czech</li><li><strong>Libraries:</strong>&nbsp;<ul><li>Default alloy libraries based on SAE, AISI, ASTM, AA standards</li><li>Users may create and edit libraries</li></ul></li><li><strong>Licensing:</strong> Varies by region. Contact your local distributor.</li><li><strong>Operating Environment:</strong><ul><li>Temperature: -10 °C to 50 °C</li><li>Humidity: 0% to 80% relative humidity non-condensing</li></ul></li><li><strong>Operating System:</strong> Proprietary</li><li><strong>Optional Accessories:</strong><ul><li>Thermo Scientific™ portable test stand</li><li>Thermo Scientific™ mobile test stand</li><li>Thermo Scientific™ field mate test stand</li><li>Thermo Scientific™ soil guard</li></ul></li><li><strong>Power Consumption:</strong><ul><li>7.4V lithium-ion battery, or 12V DC, 3A, 36W power supply</li><li>Hot swap functionality keeps analyzer powered during battery replacements</li></ul></li><li><strong>Security Features:</strong> Password-protected user security</li><li><strong>Software:</strong> Support Software: Niton Data Transfer (NDT) PC software</li><li><strong>Spot Size:</strong> 8 mm collimation</li><li><strong>Standard Accessories:</strong><ul><li>Locking shielded carrying case</li><li>Two (2) lithium-ion battery packs</li><li>One (1) 110/220 VAC battery charger/ AC adaptor</li><li>Check samples</li><li>Belt holster</li><li>Safety lanyard</li><li>PC connection cables (USB and RS-232)</li></ul></li><li><strong>System Details:</strong> Built-in standardization via automatic system check</li><li><strong>Weight (English):</strong> 3.4 lbs with battery</li><li><strong>Weight (Metric):</strong> 1.53 kg with battery</li><li><strong>X-Ray Source Type:</strong><ul><li><strong>X-Ray Tube:</strong> Ag anode (6–45 kV, 1–200 µA, 2W max)</li><li>Dynamically adjustable current for optimal sensitivity on every analysis</li></ul></li><li><strong>Applications:</strong> Identify pure metals and alloys, detect tramp elements, or obtain geochemical data</li><li><strong>Detector Type:</strong>&nbsp;<ul><li>Silicon Drift Detector (SDD)</li><li>Detector ProGuard protection included</li></ul></li><li><strong>Tube Voltage:</strong> 6 to 45 kV</li><li><strong>Unit Size:</strong> Each</li></ul><h3><strong>Which analyzer for your application?</strong></h3><figure class="image"><img style="aspect-ratio:1024/1102;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg" alt="Thermo Scientific™ Niton™ handheld XRF Analyzers - Niton handheld XRF analyzers are built for rugged use and deliver rapid, lab-quality results" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg 145w," sizes="100vw" width="1024" height="1102"></figure><blockquote><h3><strong>Helpful links</strong></h3><ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-xrf-analyzer-selection-guide.html">Which XRF analyzer is right for me?</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-xrf-analyzer-rental-leasing.html">Should I rent or lease this product?</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/xrf-radiation-safety-training.html">Where can I get radiation safety training?</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/spectroscopy-elemental-isotope-analysis-learning-center/elemental-analysis-information/xrf-technology.html">What is XRF Technology?</a></li><li>What are the applications for this handheld XRF analyzer?<ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/portable-scrap-metal-recycling-analysis.html">Scrap Metal Recycling</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/portable-manufacturing-metal-fabrication-analysis.html">Manufacturing and Metal Fabrication</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/positive-material-identification-oil-gas.html">Positive Material Identification</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-mining-exploration-solutions.html">Mining and Exploration</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/portable-precious-metals-jewelry-analysis.html">Precious Metals</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-consumer-safety-regulatory-solutions.html">Consumer Safety &amp; Regulatory</a></li></ul></li></ul></blockquote></div>

Thermo Scientific Niton XL3t GOLDD+ XRF Analyzer

High-performance handheld XRF analyzer with GOLDD™ technology for fast, accurate analysis of metals, light elements, ores, soils and contaminants – no helium or vacuum needed.

<div><div><div><p><strong>Industries from mining and exploration to scrap metal recycling depend on fast, accurate elemental analysis. The Thermo Scientific™ Niton™ XL3t GOLDD+ XRF Analyzer provides reliable, real-time data for sample identification and positive material identification for even difficult-to-analyze light elements, without helium purging or vacuum pumps.&nbsp;</strong></p><p>The <strong>Niton XL3t GOLDD+ Analyzer</strong> delivers a feature-rich package enhanced with Geometrically Optimized Large Area Drift Detector (GOLDD™) technology for improved light element (Mg-S) analysis, the lowest limits of detection and fastest measurement times.</p></div><div><h3><strong>⚡ Performance:</strong></h3><p><strong>GOLDD Technology:</strong>&nbsp;When low detection limits and high sample throughput are critical, the Niton XL3t GOLDD+ XRF analyzer delivers measurement times up to <strong>10-times faster</strong> than conventional Si-PIN detectors and up to <strong>3-times more precise </strong>than conventional smaller silicon drift detectors (SDD) - without helium purge or vacuum. For further enhancing light element analysis, a helium purge option is available. Niton analyzers also feature the highest performance X-ray tube and speed detector available on the market.</p><h3><strong>🧪 Wide Range of Applications:</strong></h3><ul><li><strong>Scrap Metal Recycling:&nbsp;</strong><ul><li>Sorts aluminum, titanium and bronze alloys, and achieves superior performance for tramp and trace element analysis.</li></ul></li><li><strong>Mining Exploration:</strong>&nbsp;<ul><li>Fast, accurate analysis of light elements.&nbsp;</li><li>Identifies anomalies near the averages naturally found in the earth's crust.&nbsp;</li><li>Facilitates advanced exploration and soil analysis, concentrate measurement, ore blending, precious metal identification and lab analysis prequalification.</li></ul></li><li><strong>Environmental:</strong>&nbsp;<ul><li>Detects contaminants such as chlorine and sulfur in sediment and arsenic in soil.&nbsp;</li><li>Identifies environmental hazards in residential, commercial and industrial settings, such as toxic drywall.</li></ul></li></ul></div></div><h3><strong>⚙️ Features</strong></h3><ul><li>Standard analytical range: Up to 30 elements from Mg to U (varies by application).</li><li>Most powerful x-ray tube on the market for handheld XRF analysis.</li><li>Point and shoot simplicity- very easy to use even by nontechnical personnel.</li><li>Rugged design for real-world industrial environments.</li><li>Nondestructive analysis with near instantaneous results.</li><li>Sealed against moisture and dust.</li><li>Ergonomically designed.</li><li>Daylight-readable icons.</li><li>Incorporates multi-language options.</li><li>Color, touch-screen display.</li></ul></div><div><h3><strong>🔗 Connectivity</strong></h3><ul><li>Integrated USB and Bluetooth™ communications provide direct data transfer to your PC or networked storage device. &nbsp;</li><li>Standard Thermo Scientific™ Niton Data Transfer (NDT™) PC software allows you to: &nbsp;<ul><li>Set operator permissions &nbsp;</li><li>Generate custom reports &nbsp;</li><li>Print certificates of analysis &nbsp;</li><li>Remotely monitor and control the instrument from your PC &nbsp;</li></ul></li><li><strong>Optional accessories: </strong>Bluetooth barcode reader, Bluetooth printer, Bluetooth GPS</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XL_3t_GOLDD_XRF_Analyzer_5_9e51a6a9ac.jpg" alt="Thermo Scientific™ Niton™ XL3t GOLDD+ XRF Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XL_3t_GOLDD_XRF_Analyzer_5_9e51a6a9ac.jpg 219w," sizes="100vw" width="650" height="464"></p><h3><strong>📏 Specifications</strong></h3><ul><li><strong>Analytical Range:</strong> Up to 30 elements from Mg to U (varies by application)</li><li><strong>Available Analytical Modes: </strong>Varies by application<ul><li>Alloy Modes: Metal Alloy, Electronics Alloy, Precious Metals</li><li>Bulk Modes: Soil, Mining, TestAll</li><li>Plastic Modes: RoHS Plastics, Toy and Consumer Goods, Plastics, TestAll, Painted Products</li><li>Custom Modes: Upon request</li></ul></li><li><strong>Certifications/Compliance:</strong> CE, RoHS</li><li><strong>Data Entry:</strong> Touch-screen keyboard, user-programmable pick lists, optional wireless remote barcode reader</li><li><strong>Data Memory:</strong> 32MB internal system memory / 128 MB internal user storage</li><li><strong>Data Storage:</strong> Internal &gt;10,000 readings with spectra</li><li><strong>Data Transfer:</strong> USB, Bluetooth and RS-232 serial communication</li><li><strong>Description:</strong> Niton XL3t GOLDD+ XRF Analyzer</li><li><strong>Dimensions (L × W × H):</strong> 9.6 × 9.05 × 3.75 in. (244 × 230 × 95.5 mm)</li><li><strong>Display Type:</strong> Tilting, color, touch-screen display</li><li><strong>Height (English):</strong> 3.75 in.</li><li><strong>Height (Metric):</strong> 95.5 mm</li><li><strong>Item Description:</strong> XL3t GOLDD+ XRF Analyzer</li><li><strong>Length (English):</strong> 9.6 in.</li><li><strong>Length (Metric):</strong> 244 mm</li><li><strong>Licensing:</strong> Varies by region. Contact your local distributor.</li><li><strong>Max. Power:</strong> 2W</li><li><strong>Operating System:</strong> Ownership</li><li><strong>Optional Accessories:</strong><ul><li>3mm small-spot collimation</li><li>Portable test stand</li><li>Stationary (benchtop) test stand</li><li>Mobile test stand</li><li>Field Mate</li><li>Thermo Scientific™ Extend-a-Pole™</li><li>Welding mask</li><li>Thermo Scientific™ HotFoot™ hot surface adapter</li><li>Soil testing guard</li></ul></li><li><strong>Power Consumption:</strong> 0 to 200 μA</li><li><strong>Security Features:</strong> Password-protected user security</li><li><strong>Standard Accessories:</strong><ul><li>Integrated CCD camera for locating and storing images</li><li>Locking shielded carrying case</li><li>Shielded belt holster</li><li>Two lithium-ion battery packs</li><li>Spare battery pack</li><li>110/220 VAC battery charger/AC adaptor</li><li>PC connection cables (USB and RS-232)</li><li>Thermo Scientific™ Niton Data Transfer (NDT™) PC software</li><li>Safety lanyard</li><li>Check samples/standards</li></ul></li><li><strong>System Electronics:</strong> 533 MHz ARM 11 CPU, 300 MHz dedicated DSP, 80 MHz ASICS DSP for signal processing</li><li><strong>Tube Type:</strong> Ag anode 50 kV and 200 μA</li><li><strong>Voltage:</strong> 6 to 50 kV</li><li><strong>Weight (English):</strong> 3 lb.</li><li><strong>Weight (Metric):</strong> 1.3 kg</li><li><strong>Width (English):</strong> 9.05 in.</li><li><strong>Width (Metric):</strong> 230 mm</li><li><strong>Applications:</strong> Sample Identification, Positive Material Identification</li><li><strong>Detector Type:</strong> Geometrically Optimized Large Area Drift Detector</li><li><strong>Tube Voltage:</strong> 6 to 50 kV</li><li><strong>Unit Size:</strong> Each</li></ul><h3><strong>Which analyzer for your application?</strong></h3><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg" alt="Thermo Scientific™ Niton™ handheld XRF Analyzers - Niton handheld XRF analyzers are built for rugged use and deliver rapid, lab-quality results" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg 145w," sizes="100vw" width="1024" height="1102"></p></div>

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