STRam Raman spectrometer for analyses through non-transparent packaging

Importance of Topic

The STRam Raman spectrometer enables non-destructive, rapid chemical analysis through non-transparent packaging, addressing critical needs in pharmaceutical, food, and industrial quality control.

Study Goals and Overview

This document details the standard delivery contents and optional accessories for the BWT-840000676 STRam Raman system. It aims to provide a concise reference for ordering, system configuration, and field deployment.

Methodology and Instrumentation

The system employs 785 nm excitation via a fiber-optic Raman probe to penetrate packaging materials. Key delivered components include:

• BWSpec® control and acquisition software with real-time peak analysis and trending
• STRam probe module featuring a 105 µm excitation fiber and 300 µm collection fiber with quartz window
• Carrying case, laser safety goggles, and calibration accessories
• BWID Pharma Raman ID software for material verification compliant with FDA 21 CFR Part 11

Optional hardware and software expand capabilities:

• Chemometric suite (BWIQ®) for PCA, PLS, SVM analyses
• Rechargeable battery pack and power cords for field use
• Raman flow cells (stainless steel or titanium) for inline liquid measurements
• Various immersion shafts and high-throughput probes for harsh environments
• Extensive spectral libraries covering chemicals, polymers, pharmaceuticals, food additives, and hazardous materials
• Video micro-sampling systems for microscopic targeting

Main Results and Discussion

The combination of portable hardware and versatile software allows on-site identification of unknown substances through packaging without sample preparation. Comprehensive accessory options ensure adaptability to diverse sample types and operating conditions. Pre-built and customizable spectral libraries streamline identification workflows, while chemometric tools enhance quantitative and qualitative analyses.

Benefits and Practical Applications

• Non-invasive testing eliminates product compromise
• Portable form factor supports field inspections in pharmaceuticals, forensics, and food safety
• Automated analysis and reporting reduce operator training requirements
• Modular accessories adapt to high-temperature, high-pressure, or immersion environments

Future Trends and Applications

Integration with machine learning for predictive maintenance and automated anomaly detection is anticipated. Expansion of spectral databases and remote monitoring capabilities will further enhance industrial process control and regulatory compliance. Advances in probe miniaturization and multispectral excitation will broaden application scope.

Conclusion

The STRam Raman system offers a flexible platform for rapid, non-destructive analysis through packaging. Its extensive accessory ecosystem and advanced software support diverse analytical scenarios, making it a valuable tool for modern quality assurance and research.

References

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