This study examines the combustion behavior of B4C/Bi2O3 pyrotechnic delay compositions as sustainable alternatives to conventional materials. Thermodynamic modeling and experimental testing were used to evaluate the influence of compaction pressure, particle size, and granule size on burning performance.Results showed that increased compaction reduced burning rates by lowering porosity and shifting combustion from convective to conductive mechanisms. Residue and gas analyses supported a multistage reaction pathway, demonstrating the potential of B4C/Bi2O3 formulations for environmentally improved pyrotechnic applications.<blockquote><h4>The original article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsomega.5c10964">Sustainable Pyrotechnics: Combustion Behavior of B4C/Bi2O3 for Delay Compositions</a></h4>Danillo F. Vianna Cantini, Vojtěch Pelikán*, Eva Schmidová, Jiří PachmanACS Omega 2026, 11, 3, 4668–4683<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1021/acsomega.5c10964">https://doi.org/10.1021/acsomega.5c10964</a><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote>Selected sections from the article follow. Formats and hyperlinks were adapted from the original.<div>Pyrotechnic delay compositions are formulations designed to create a specific delay time, determined primarily by their burning rate. These compositions are essential in timing energetic events and are used extensively in both civilian and military applications. <a href="javascript:void(0);">(1)</a> This broad usage leads to diverse motivations for studying such materials. In civilian contexts, such as mining, the focus is typically on safety and cost-effectiveness. <a href="javascript:void(0);">(2)</a> For military purposes, reliability and precision are key factors, often with stringent performance requirements. <a href="javascript:void(0);">(3)</a>Pyrotechnic delay compositions are classified based on their combustion behavior into gassy or gasless types. In confined, sealed and obturated environments, gasless compositions are favored, to avoid gas buildup. <a href="javascript:void(0);">(1,4)</a> However, in unconfined or vented systems, gassy compositions are not problematic. For example, in fireworks, where combustion gases freely dissipate, <a href="javascript:void(0);">(1)</a> or in vented housings like hand grenades or signaling devices, gassy delays are acceptable. <a href="javascript:void(0);">(5,6)</a>In gassy compositions, the burning rate is influenced by the loading (or consolidation) pressure. Hot gases generated by the chemical reaction penetrate gas channels (voids) in the material, igniting unreacted material through a process known as convective heating. As loading pressure increases, these voids are gradually reduced, which diminishes convection and subsequently lowers the burning rate. In contrast, for gasless compositions, burning is driven by conductive heating, where heat is transferred through direct particle-to-particle contact, leading to the opposite effect. <a href="javascript:void(0);">(7−9)</a>Historically, up until World War II, black powder served as the foundation for most delay elements. Nowadays, it continues to be utilized for this function and others, but on smaller scales. <a href="javascript:void(0);">(1)</a> Some more recent and traditional formulations for pyrotechnic compositions include fuels like silicon, boron, tungsten, zinc, iron, zirconium, and manganese. Examples of these are Si/Pb3O4, <a href="javascript:void(0);">(8,10)</a> B/BaCrO4 <a href="javascript:void(0);">(8)</a>, W/BaCrO4/KClO4, <a href="javascript:void(0);">(5,6,11)</a> Zn/PbO2, <a href="javascript:void(0);">(12)</a> Fe/BaO2, <a href="javascript:void(0);">(13)</a> Zr/KClO4, <a href="javascript:void(0);">(8)</a> and Mn/PbCrO4/BaCrO4. <a href="javascript:void(0);">(14)</a>Currently, researchers are actively developing several new formulations for pyrotechnic delays. One of the main motivations for this is the need to transform these compositions into “greener” ones. <a href="javascript:void(0);">(1,2)</a> This means that compositions that could cause problems for the environment or human health should be avoided. To achieve this sustainability, the identification and replacement of known or potentially harmful, toxic, and carcinogenic compounds is vital. <a href="javascript:void(0);">(10)</a> Heavy metals, persistent organic pollutants, toxic gases, volatile organic compounds and known causers of human health problems are examples of such substances to be removed. <a href="javascript:void(0);">(2,5,15)</a>Specifically, there are several attempts to replace lead, barium, chromates, and perchlorates. <a href="javascript:void(0);">(15)</a> The reason is that most of the established delay formulations used today contain these substances. <a href="javascript:void(0);">(2,5)</a> Lead, barium and chromium (contained in chromates) are heavy metals and are known to cause serious health problems in human, specially to nervous, cardiovascular and respiratory systems. <a href="javascript:void(0);">(5,16)</a> Perchlorates are well-documented substances and are used in various pyrotechnic applications. However, they are widely recognized as contributors to thyroid issues. <a href="javascript:void(0);">(5)</a>From the above, it is clear that modern strategies in pyrotechnics are increasingly focused on developing new materials that prioritize both efficiency and sustainability. This shift imposes numerous restrictions, meaning that formulations must be designed with precise planning and thorough investigation to meet both performance and environmental standards.Boron could be considered the ideal fuel for pyrotechnic reactions due to its high energy content. However, it presents combustion issues for its limited reactivity due to boron oxide layer and boron agglomerates formation upon heating. <a href="javascript:void(0);">(17)</a> The boron oxide layer acts as a barrier, hindering oxygen (O) diffusion and consequently limiting the oxidation of boron. <a href="javascript:void(0);">(18)</a>Boron carbide (B4C) is a natural candidate for combustion processes due to its lower ignition point, which is attributed to its higher reactivity. This reactivity stems from the diffusion of carbon (C) particles, which oxidize into gaseous products. These gaseous products create diffusion channels that penetrate the boron oxide layer, breaking down the layer and agglomerates, thereby further improving the reaction. <a href="javascript:void(0);">(18,19)</a> B4C presents better combustion properties, with better burning stability and reliable self-propagation, resulting in better combustion efficiency. <a href="javascript:void(0);">(17)</a>Bismuth trioxide (Bi2O3) is an attractive oxidizer for pyrotechnic delay compositions due to several advantageous properties. Its high oxygen content and efficient oxygen release facilitate sustained combustion, while its favorable thermal properties, including a relatively low melting and decomposition temperature, ensure that oxygen is available at precisely the right moment to support a controlled reaction. <a href="javascript:void(0);">(20)</a> Additionally, Bi2O3 high density allows for compact formulations, promoting consistent and reliable burn rates. Also, it has a low heat of formation (approximately −582 kJ/mol), which is crucial to minimize the energy required to initiate its decomposition. This enhances the overall reaction efficiency, allowing Bi2O3 to rapidly release oxygen without consuming excessive energy, thus ensuring sustainable and stable combustion. <a href="javascript:void(0);">(8)</a>In addition to their technical advantages, Bi2O3 and B4C offer a significant environmental benefit: they are considered more eco-friendly compared to other materials commonly used in pyrotechnic compositions. Bi2O3 serves as a less toxic alternative to traditional oxidizers like lead-based compounds, reducing the risk of environmental contamination and exposure to harmful heavy metals. <a href="javascript:void(0);">(1,8,16)</a> Similarly, B4C contributes to cleaner combustion, producing fewer pollutants and minimizing the environmental impact. <a href="javascript:void(0);">(5)</a> This makes both materials not only effective but also greener choices for sustainable pyrotechnic applications.<h4>2. Experimental Section</h4><h5>2.8. Material Characterization</h5>Particle and granule size distribution were measured with a Malvern Mastersizer 3000 (Malvern Panalytical). Scanning Electron Microscopy (SEM) was carried out with a TESCAN MIRA (TESCAN) to examine morphology and confirm particle size. A 40 cm3 combustion chamber was used to analyze pressure profile, quantify solid residues, and collect combustion gases for further analysis. Fourier Transform Infrared Spectroscopy (FTIR) was performed using a <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2392">Nicolet iS50 FT-IR</a> (Thermo Scientific) and standardized nitrogen (N2) background to identify gas-phase products. Thermal stability and water content assessments were conducted using TGA (NETZSCH TG 209 F3 Tarsus) and DSC (NETZSCH DSC 200 F3 Maia). Energy Dispersive X-ray Spectroscopy (EDS) was performed using a Bruker Quantax 200 (Bruker) for semiquantitative chemical composition analysis of the combustion residues. X-ray diffraction (XRD) analyses were performed using a Rigaku MiniFlex diffractometer for complementary phase identification, while surface chemical states were characterized by X-ray photoelectron spectroscopy (XPS) using a Scienta Omicron ESCA2SR system.<h4>3. Results and Discussion</h4><h5>3.7. FTIR Analysis of Combustion Gases</h5><a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsomega.5c10964#fig10">Figure 10</a> compares the FTIR spectra of combustion chamber gases from stoichiometric (blue) and fuel-rich (red) tests, highlighting CO and CO2 as the main species, consistent with Horiuchi. <a href="javascript:void(0);">(18)</a> Normalizing their absorbance to concentration using standard references yielded CO2/CO ratios of 0.67 (stoichiometric) and 0.34 (fuel-rich). However, a quantitative analysis is approximate and inherently imprecise, as potential contamination during gas collection and measurement could affect the results, given the challenge of maintaining a completely controlled internal atmosphere. A small fraction of hydrocarbon species (e.g., CH4, C2H4, and C2H2) was also identified in both samples.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ACS_Omega_2026_11_3_4668_4683_Figure_10_Comparative_FTIR_spectra_of_combustion_gas_compositions_in_a_combustion_chamber_ac7b7daf84.jpg" alt="ACS Omega 2026, 11, 3, 4668–4683: Figure 10. Comparative FTIR spectra of combustion gas compositions in a combustion chamber." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ACS_Omega_2026_11_3_4668_4683_Figure_10_Comparative_FTIR_spectra_of_combustion_gas_compositions_in_a_combustion_chamber_ac7b7daf84.jpg 245w," sizes="100vw" width="1956" height="989">While experimental results indicate a higher CO2 presence than predicted, the overall trend aligns with expectations─higher fuel content shifts combustion products toward less oxidized species. Notably, the identified gaseous products are relatively simple and exhibit low toxicity compared to halogenated or metal-containing species commonly found in traditional pyrotechnic formulations, supporting the potential of this system as a more environmentally friendly alternative.Since the reaction involves both condensed-phase reactants and products, characterizing the solid residues is essential to evaluate the extent of reaction and gain insight into the actual progression of the reaction pathway. For this, SEM imaging and EDS analysis were employed to investigate the morphology and elemental composition of the combustion residues.<h5>3.8. SEM and EDS of Burning Residues</h5><a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsomega.5c10964#fig11">Figure 11</a> presents the SEM analysis of solid residues from the combustion of B4. <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acsomega.5c10964/suppl_file/ao5c10964_si_001.pdf">Figure S5</a> exhibits images of the other samples. <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsomega.5c10964#fig11">Figure 11</a>a shows the top view of the burned delay element, revealing the distribution of residues across the surface, while <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsomega.5c10964#fig11">Figure 11</a>b provides a magnified view of a region rich in bright spherical structures. These spheres are likely bismuth that transitioned through a liquid or gaseous phase during the reaction and solidified upon cooling. This phenomenon of spherical formation due to phase transition is well-documented in the literature. <a href="javascript:void(0);">(33)</a><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ACS_Omega_2026_11_3_4668_4683_Figure_11_SEM_analysis_of_B4_after_burning_8fc7a8f520.jpg" alt="ACS Omega 2026, 11, 3, 4668–4683: Figure 11. SEM analysis of B4 after burning: (a) top view (50 ×) of the burned delay element showing the distribution of solid residues across the surface; (b) magnified view (1 k×) of a region rich in bright spherical structures." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ACS_Omega_2026_11_3_4668_4683_Figure_11_SEM_analysis_of_B4_after_burning_8fc7a8f520.jpg 245w," sizes="100vw" width="2092" height="831"><h5>3.10. Surface Chemistry of Combustion Residues (XPS)</h5>Survey spectrum scans identified the main photoelectron lines corresponding to carbon, oxygen, boron, and bismuth. High-resolution scans for the O 1s, C 1s, B 1s, and Bi 4f regions of B4 are presented in <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsomega.5c10964#fig19">Figure 19</a>, allowing detailed peak deconvolution and chemical assignment.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ACS_Omega_2026_11_3_4668_4683_Figure_19_XPS_high_resolution_spectra_of_O_1s_C_1s_B_1s_and_Bi_4f_regions_for_B4_5c6064d013.jpg" alt="ACS Omega 2026, 11, 3, 4668–4683: Figure 19. XPS high-resolution spectra of O 1s, C 1s, B 1s, and Bi 4f regions for B4." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ACS_Omega_2026_11_3_4668_4683_Figure_19_XPS_high_resolution_spectra_of_O_1s_C_1s_B_1s_and_Bi_4f_regions_for_B4_5c6064d013.jpg 214w," sizes="100vw" width="2049" height="1498">The analysis confirmed B2O3 as a major surface product and indicated the presence of unreacted B4C in the B4 sample through B–C bonds. sp2 carbon was also detected in B4, suggesting possible graphite formation, as predicted in thermodynamic calculations. A2 showed more Bi3+ than B4, supporting that the stoichiometric composition had more residual Bi2O3, while the fuel-rich B4 sample promoted greater reduction to Bi0. The presence of Bi3+ on the surface observed may result from postcombustion reoxidation of Bi0. These results reinforce the proposed reaction pathway and the role of fuel excess in enhancing reaction completeness. In this analysis, the B 1s spectrum further confirms the absence of BN by the lack of B–N peaks, consistent with the EDS results, which also revealed no detectable nitrogen signal.All experimental findings contribute to the fundamental understanding of boron carbide and bismuth oxide reactions under both basic and applied conditions, particularly in delay compositions. These results provide new insights into the reaction pathway and the underlying combustion mechanism.<h4>4. Conclusions</h4>Stoichiometric formulations of B4C/Bi2O3, which ignited when not pressed, failed to burn after being lightly compacted; a fuel-rich composition is necessary to ensure combustion. The fuel-rich compositions ignited readily and maintained combustion without quenching. Water facilitated the granulation process and improved the final composition. With increasing loading pressure, burning rates decrease due to reduced convective heat transfer, leading the combustion process to transition toward a conductive regime. Particle size also impacted combustion, particularly with larger Bi2O3 particles, which influenced the combustion profile up to a certain threshold. Additionally, the granule size of the final composition was found to alter the burning behavior, with larger granules promoting faster combustion at lower pressures.Thermodynamic calculations provided an initial insight into the reaction process. The findings show that the reaction progresses through distinct stages: starting in a solid–solid preignition phase, transitioning to a solid–liquid phase as components melt, and culminating in a gas phase marked by significant product volatilization, illustrating a complete combustion evolution.FTIR analysis confirmed that the main gaseous products are CO and CO2, indicating reduced environmental toxicity. Elemental and phase analyses confirmed that the reaction followed the expected pathway, with Bi and B2O3 as the predominant products. No Bi2O3 was detected by XRD, indicating that the oxidizer was fully consumed in the bulk. Morphological analysis of the products suggests that, upon cooling, bismuth solidifies into small metallic spheres, while surface analysis indicates that B2O3 remains predominantly in the outer layer. Altogether, the results are consistent and complementary, reinforcing the reliability and scientific rigor of the study.All these observations accentuate the necessity of conducting experiments under application-specific conditions. These findings not only enhance our understanding of the combustion dynamics of low toxicity B4C/Bi2O3 mixtures but also underscore their potential for practical applications requiring precise delay times and environmental sustainability. The successful use of water as a green solvent further highlights the viability of developing sustainable pyrotechnic compositions. This research advances the field by providing valuable insights into optimizing performance while minimizing environmental impact through careful material selection and process control.</div>

Sustainable Pyrotechnics: Combustion Behavior of B4C/Bi2O3 for Delay Compositions

In the week from May 11, the following webinars await you in the field of atomic and molecular spectroscopy and spectrometry<blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinars">👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</a></h4>👉 Search and filter in the largest global database with over 5 500 GC, LC, MS and spectroscopy webinars.</blockquote><h5>1. Thermo Fisher Scientific: Uncovering Microplastics: Identification, Quantification, and Exposure Assessment</h5><ul><li>Tu, 12.5.2026 08:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6136">Registration</a></li></ul>In this webinar, we will explore complementary analytical solutions for comprehensive microplastics characterization.<h5>2. SPECTRO Analytical Instruments: Elemental Analysis of Superalloys: Ensuring Performance in Extreme Applications</h5><ul><li>Tu, 12.5.2026 10:30 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6170">Registration</a></li></ul>Learn how accurate elemental analysis ensures superalloy performance, with OES and XRF solutions for reliable quality control from lab to field.<h5>3. Agilent Technologies: What have you been smoking? Elemental Analysis in Cannabis and Cannabis Products with ICP-MS</h5><ul><li>Tu, 12.5.2026 20:30 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6063">Registration</a></li></ul>Learn how automated calibration and dilution streamline ICP-MS food testing workflows, improving accuracy, traceability, and productivity while addressing rare-earth doubly charged interferences.<h5>4. AZoM: Faster REE Exploration Decisions with XRF Technology Explained</h5><ul><li>We, 13.5.2026 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6195">Registration</a></li></ul>Join the webinar to see how handheld XRF provides a significant advantage in today's fast-paced REE landscape.<h5>5. Bruker: Advancing Industrial Metrology Automation with Bruker's Dimension AFMs</h5><ul><li>We, 13.5.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6172">Registration</a></li></ul>This webinar will explore how Dimension AFM platforms support increasing levels of automation, from scripted measurements to data-driven control.<h5>6. Anton Paar: Polymer Rheology: Impact of Humidity on Material Behavior</h5><ul><li>We, 13.5.2026 18:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/5801">Registration</a></li></ul>Discover how humidity impacts polymers and soft materials. Learn how moisture alters rheology, tackiness, curing, and flowability through real case studies across films, adhesives, foods, and powders.<h5>7. LECO: TOC Determination in Soil and Waste</h5><ul><li>Th, 14.5.2026 14:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6038">Registration</a></li></ul>Join this webinar to explore modern methods for TOC determination in soils and waste. Learn how standardized approaches, instrumentation, and method selection influence data quality and regulatory compliance.

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Routine chemical analysis typically involves several steps, e.g. selection of procedure, sampling, sample preparation, measurement, result calculation, uncertainty estimation, and reporting to customer. Based on the result, important decisions and actions are taken. The steps before and after the measurement are often referred to as “pre- and post-analytical”. There are many sources of uncertainty associated with this work, some of which can actually limit the overall quality.&nbsp;Proficiency testing (PT) and external quality assessment (EQA) schemes are effective means of assessing the quality of routine analyses. However, if there are specific procedures, either before or after the measurement, which are applied to the routine samples, but not to the PT test sample, the result reflects only the quality of part of the measurement process. Pre- and post-analytical PT/ EQA schemes are already widely used in laboratory medicine. The standard ISO 15189, that underpins accreditation of medical laboratories, stresses that EQA schemes should “... have the effect of checking the entire process including pre- and post-examination procedures ...”&nbsp;The examples in this leaflet illustrate the potential and importance of pre- and post-analytical PT/EQA. They are intended as an inspiration for the providers to further develop their external quality control activities.<h4>Pre- and post-analytical PT/EQA – a means for harmonisation&nbsp;</h4>By illustrating, e.g. lack of adherence to guidelines, or variation in sample preparation, or inconsistency in interpretation, pre- and post-analytical PT/EQA schemes pinpoint problems not apparent in other schemes. This may lead to improved harmonisation and changes to guidelines and standards.<h4>Example 1: Interpreting clinical chemistry information&nbsp;</h4>Patient background information together with analytical results can be used to check agreement of interpretational advice given by medical doctors. This type of scheme can, therefore, include both pre- and post-analytical aspects. The provider, e.g. through an expert group, ranks the quality of participants’ response and suggestions, and presents them in the report with comments.<h4>Example 2: Sampling requests in microbiology&nbsp;</h4>Using the scenario of food poisoning, pre- &amp; post-analytical aspects of sampling requests in a microbiology scheme can be highlighted. The provider gives information about food type, symptoms, and incubation time with a simulated sample. Participants choose which organism(s) to test for. The associated laboratory work involves examination of samples, report on method(s) of choice and results. Participants could, e.g. be asked to specify which toxins or pathogens are likely to cause the food poisoning and state whether or not they will disseminate information, e.g. to hospitals or food suppliers. The feedback report would then show the results of each participant together with the comments of the provider.&nbsp;<h4>Example 3: Toy testing&nbsp;</h4>Faulty design, usage and chance play a role in injury and death incidents related to children’s toys. Toy safety is the practice of ensuring that toys are safe, usually through the application of set safety standards. The PT provider sources a toy, performs visual assessment of its homogeneity, and distributes the samples. Participants are requested to assess the toy against the European standard EN 71 and they have to decide which clauses of the standard apply. The clauses chosen define the test(s) to be carried out. The feedback report will contain a “model answer” including clauses, tests and labeling requirements (when applicable).&nbsp;<h4>Example 4: Monitoring drinking water quality&nbsp;</h4>A post-analytical application can be underpinned by legislation and national regulations (Directive 98/83/EC). Participants receive a synthetic drinking water sample with properties close to one or more limiting values. They are requested to deliver results, uncertainties and a “pass/fail” recommendation to the customer. The recommendations of the provider are listed in the feedback report for educational purposes. Information can be fed back also to regulators to serve, e.g. as basis for further discussions.&nbsp;<blockquote><h5>More information / further reading&nbsp;</h5>Information about PT providers and schemes can be obtained from your national accreditation body, from the <a target="_blank" rel="noopener noreferrer" href="https://www.eptis.org/">EPTIS website</a> or from other national or international organisations.</blockquote>

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Eurachem is a European network promoting international traceability of chemical measurements and good analytical practice. It provides expert guidance, supports method validation, uncertainty evaluation, proficiency testing, and facilitates discussion on technical and policy issues in analytical quality.

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UV-Vis Thermal Melts can be a time consuming bottle-neck in the lab. We will discuss how melt measurements can instead be collected rapidly and accurately with the <a href="https://lcms.cz/products/628">Cary 3500 UV-VIS Spectrometer</a>.
<blockquote>
Presenter: Scott Melis, PhD (Application Scientist, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Scott Melis has a PHD in Physics from Georgetown University in Washington, DC and started with Agilent in 2021 as a Molecular Spectroscopy Application Scientist. In his graduate work, Scott studied nanoparticle formation and growth for a variety of applications. Projects that he worked with include developing processes to deposit and characterize semiconducting molecular nano-cocrystals for use in optoelectronic devices as well as controlling polymer nanoparticle size through rapid mixing conditions.
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Agilent: Save Time With Fast UV-Vis Thermal Melts

Save Time With Fast UV-Vis Thermal Melts

<h4>Overcome the challenges associated with complex food samples and streamline your QA/QC processes by harnessing the full potential of UV-Visible absorption spectroscopy.</h4>
UV-Visible absorption spectroscopy is a popular technique for quality assurance and quality control in the food industry. While QA/QC testing of simple products like food dyes can be straightforward, how can successful analysis of complex food products be achieved?
Working with complex food samples can pose challenges. With multiple components including absorbers present, it becomes crucial to ensure accuracy in the analysed results. As a highly versatile and non-destructive technique, UV-Visible absorption spectroscopy is a powerful and reliable method for quantitative analysis. This webinar will demonstrate the application of UV-Visible spectroscopy in food analysis and also provide best practices to maximise the efficiency and accuracy of this technique.
Dr. Jennifer Empey-Kohl, Applications Scientist with Thermo Fisher Scientific, will address common issues that can arise during the analysis process and offer valuable tips on environmental considerations, instrument parameters, and sample preparation to optimise your results. She will also present best practices to maximise the efficiency and accuracy of this technique.
<h5>Key learning points:</h5>
<ul>
<li>Gain insights into best practices for UV-Visible absorption spectroscopy, including sample preparation and how to choose the best instrument parameters</li>
<li>Learn strategies for analysing UV-Visible spectra of matrixed samples, as well as how to correct for known contaminants</li>
<li>Understand environmental and sample factors that can affect the measured absorbance of a given analyte</li>
<li>Take advantage of the live Q&amp;A to ask your own questions and obtain expert guidance</li>
</ul>
<blockquote>
Presenter: Dr. Jennifer Empey-Kohl, (Applications Scientist, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Jennifer Empey-Kohl is an Applications Scientist with Thermo Fisher Scientific where she develops application notes and provides support for the cuvette-based UV-Visible instruments. Prior to this position, she received her PhD in Chemistry from The Ohio State University where she used various steady-state and time-resolved spectroscopic techniques to study colloidal nanoparticles.
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Don’t miss this chance to learn how to optimize your UV-Visible spectroscopy workflow and achieve reliable results for your food analysis. Register now and secure your spot!

New Food Magazine: UV-Vis analysis of food samples: tips and tricks for QA/QC

UV-Vis analysis of food samples: tips and tricks for QA/QC

UV-Visible spectroscopy in food analysis - best practices to maximise the efficiency and accuracy

<a href="https://gcms.labrulez.com/products/1016">Wiley’s KnowItAll software</a> offers integrated solutions to identify, analyze, and manage analytical and chemical data. Combined with comprehensive high-quality spectral reference databases, it provides one of the most advanced technologies available for fast, reliable spectral analysis.
<a href="https://gcms.labrulez.com/products/1016">KnowItAll</a> supports multiple techniques and instrument vendor formats. So whether you use one or more techniques, it can work across a single lab using one instrument or multiple labs with multiple instrument types. Using a vendor neutral solution like KnowItAll is important further in that it future proofs your lab, so even if you add instruments or change vendors your analytical workflow stays intact. 
In this session, we will demonstrate through a series of live examples some of the powerful spectral search tools available within the KnowItAll for unknown spectral analysis in a multi-technique laboratory setting. 
<h5>You will discover:</h5>
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<li>How KnowItAll offers a consolidated workflow for one or more analytical techniques by combining all the tools needed for spectral analysis and data management into a single, easy-to-use interface. </li>
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<blockquote>
Presenter: Dr. Leanna Ergin (Assistant Editor, Wiley Science Solutions)
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Wiley: Introduction to KnowItAll for Multi-Spectral Techniques

Introduction to KnowItAll for Multi-Spectral Techniques

We will demonstrate some of the powerful spectral search tools available within the KnowItAll for unknown spectral analysis in a multi-technique laboratory

Event Program
<ul>
<li>Why is it beneficial to automate UV Vis spectroscopic workflows</li>
<li>The available automation solutions for UV Vis spectroscopy</li>
<li>The main benefit of each type of automation</li>
<li>How to chose the right automation for your laboratory</li>
<li>Examples of how automated systems for UV Vis spectroscopy are used in real-life</li>
</ul>
In this live webinar, we will look at how you can streamline the optical spectroscopy workflows in your laboratory to increase efficiency and operating safety, while at the same time improve result quality and help support compliance with regulations.
We will look at what automation solutions are available for UV Vis spectroscopy today and discuss what aspects need to be considered in order to choose the automation solution that best fits your needs.
<h5>Learn more about automation solutions for UV Vis spectroscopy.</h5>
Automation solutions greatly simplify UV Vis spectroscopy workflows and significantly increase productivity in the lab. They enable unattended operation of spectroscopic systems and free lab staff for other tasks, while the system performs the analysis autonomously in the background. Automating spectroscopy solutions means more than just pumping a sample in a cell for the acquisition of a measurement: it comes in many forms and solutions to fit every laboratory&#39;s individual needs.
<blockquote>
Presenter: Anika Adams (Product Manager SPG UV/VIS)
</blockquote>
<blockquote>
Presenter: Dr. Fabian Müller (Product Manager SPG UV/VIS)
</blockquote>

Mettler-Toledo: Automation for UV-Vis Spectroscopy

Automation for UV-Vis Spectroscopy

Learn How to Increase the Efficiency and Security of Your UV Vis Workflows with Unattended Operation.

At the forefront of scientific inquiry lies the transformative potential of high-throughput screening in advancing drug discovery. Through the ingenious integration of cutting-edge technologies and automation, industry leaders are reshaping the landscape, enhancing efficiency and scaling up processes like never before.
In this exclusive extended webinar, immerse yourself in a world of innovation as our expert speakers unveil state-of-the-art systems and workflows designed to optimize screening assays with unparalleled throughput and reproducibility. Discover how these advancements propel drug discovery pipelines forward with unprecedented speed and precision.
Attend this webinar to:
<ul>
<li>Understand the benefits of integrated high-throughput screening automation in enhancing efficiency and scalability in drug discovery processes</li>
<li>Explore the features of a high-capacity workcell designed for complex compound screens with multiple analytical readouts</li>
<li>Learn about the advantages of a complete walkaway and tipless system in reducing downtime, minimizing waste and accelerating compound screening processes</li>
</ul>
<h3>Agenda</h3>
<h4>TALK 1</h4>
Next-Level Efficiency: Supercharged High-throughput Screening Capacity Through Integrated Automation
Discover how Automata’s cutting-edge platform streamlines drug discovery workflows, boasting a tipless system for seamless operation and enhanced scalability. Learn how the high-capacity workcell empowers researchers to conduct complex compound screens with unparalleled efficiency and reproducibility.
In this session, Alice Tone-Fernandez from Automata will valuable insights into leveraging integrated automation to supercharge high-throughput screening capacity, ultimately revolutionizing efficiency in drug discovery processes.
In her talk, she will:
<ul>
<li>Discuss the benefits of integrated high-throughput screening automation in enhancing efficiency and scalability in drug discovery processes</li>
<li>Explore the features of a high-capacity workcell designed for complex compound screens with multiple analytical readouts</li>
<li>Showcase the advantages of a complete walkaway and tipless system</li>
</ul>
<blockquote>
Presenter: Alice Tome-Fernandez (Senior Application Scientist, Automata)
</blockquote>
<h4>TALK 2</h4>
96 and 384 channel Electronic Pipettes from INTEGRA: Affordable, Simple, Small and Powerful
96 and 384 channel Electronic Pipettes from INTEGRA: Affordable, Simple, Small and Powerful
If you’re working in 24, 96, 384, or even 1536 plate formats, this session will show you 3 instruments which will make you faster, give you more reproducible results, are simple to learn and don’t take up much space - while fitting in every budget. The perfect productivity upgrade for any lab looking to get better.
In this session, Tom Bentivegna from INTEGRA will provide insights into best practices for utilizing these electronic pipettes effectively. Whether you’re a seasoned researcher or new to the field, this talk will provide valuable guidance for optimizing your laboratories workflows.
In his talk, he will:
<ul>
<li>Discuss how to optimize 96 and 384 well-plates to be faster and more reproducible</li>
<li>Showcase novel devices to enhance your high-throughput screening workflows</li>
</ul>
<blockquote>
Presenter: Tom Bentivegna (Group Product Manager, INTEGRA Biosciences)
</blockquote>
<h4>TALK 3</h4>
High-throughput SPR Assay for FcγR Binding to Drug Candidates on the New Carterra LSAXT
Discover the power of high-throughput surface plasmon resonance (HT-SPR) for assessing FcγR binding to drug candidates using the new Carterra LSAXT platform. In this webinar, Peter Hsueh, PhD from ACROBiosystems will showcase how this streamlined approach, coupled with ACROBiosystems’ recombinant FcγR proteins, enables rapid characterization of FcγR interactions across species.
In his talk, he will:
<ul>
<li>Explain the significance of FcγR binding in therapeutic efficacy and cross-reactivity assessment</li>
<li>Exploring a streamlined approach using HT-SPR on the Carterra LSAXT platform</li>
<li>Showcase the benefits of increased sensitivity, reproducibility and time/resource savings in characterizing FcγR interactions compared to traditional SPR methods</li>
</ul>
<blockquote>
Presenter: Peter Hsueh, PhD (Marketing Product Manager, ACROBiosystems)
</blockquote>

Technology Networks: Revolutionizing Drug Discovery: Unleashing the Power of High-Throughput Screening

Revolutionizing Drug Discovery: Unleashing the Power of High-Throughput Screening

Learn about state-of-the-art systems and workflows designed to optimize screening assays with unparalleled throughput and reproducibility.

The Power of High-Throughput Screening

There are numerous reasons why bringing the spectrophotometer to the sample instead of the tradition method of bring the sample to the spectrophotometer makes sense for making a measurement. During this presentation we will examine some of the reasons and look at aspects of using fiber optics on the Cary 60. Practical examples of samples will also be discussed.
<blockquote>
Presenter: Mark Fisher, PhD (Application Engineer, Molecular Spectroscopy, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Mark, an Application Scientist for Agilent Technologies, has over 35 years of experience in molecular spectroscopy. He has held roles in Agilent&#39;s UV-Vis-NIR, fluorescence, and atomic absorption product portfolios. In addition to identifying industry trends and new business needs, Mark&#39;s responsibilities include application development, pre and post-sales support, as well as acting as a customer advocate for new product and technology opportunities. Mark received his doctorate in analytical chemistry from the University of Nebraska-Lincoln.
</blockquote>

Agilent: The Art of Remote Sampling Using a Cary 60 and Fiber Optics

The Art of Remote Sampling Using a Cary 60 and Fiber Optics

During this presentation we will examine some of the reasons and look at aspects of using fiber optics on the Cary 60.

Event Program
<ul>
<li>Basics of spectroscopy theory and applications</li>
<li>How UV Vis instruments work</li>
<li>Application of Beer-Lambert law</li>
<li>How to measure a sample and record its UV Vis spectra</li>
<li>How to analyze UV Vis spectra using PC software</li>
<li>Good UV Vis practices</li>
</ul>
Join our free live webinar and learn good practices for teaching UV Vis spectroscopy. The webinar will combine theory study with a live demo using a UV Vis spectrometer on the lab bench and spectra analysis software on a laptop.
<blockquote>
Presenter: Dr. Friedrich Menges (Owner/ Creator/ Developer at Spectroscopy Ninja)
</blockquote>
<blockquote>
Presenter: Dr. Fabian Müller (Product Manager SPG UV/VIS)
</blockquote>

Mettler-Toledo: UV Vis Spectrophotometry for Teaching and Education

UV Vis Spectrophotometry for Teaching and Education

Learn Good Practices for Teaching UV Vis Essentials.

Explore the intricacies of the world through the lens of nucleic acids—the building blocks of life. Nucleic acids, including the DNA and RNA, play pivotal roles across diverse fields, such as the following examples:
<ul>
<li>Biopharmaceuticals: The development of mRNA vaccines for COVID-19 highlights the rapid advancements and powerful potential of nucleic acid therapeutics.</li>
<li>Food safety: Nucleic acid-based detection methods can act as an effective tool to identify foodborne viruses, detect food allergens, and even uncover instances of food fraud.</li>
<li>Forensics: DNA analysis can shed new insights into crime scene investigations.</li>
<li>Medical diagnostics: Nucleic acids can be used to detect genetic disorders, cancer biomarkers, and infectious diseases etc.</li>
</ul>
In this Shimadzu Digital Classrooms, join us as we learn more about nucleic acid analysis, using UV-Vis spectroscopy and microchip electrophoresis. We will be introducing Shimadzu’s innovative technologies —TMSPC-8i, BioSpec-nano, and MultiNA—and showcase how they each play a crucial role in various spheres of science and industry. Register now!
Learning Objectives:
<ul>
<li>Learn about the capabilities of Shimadzu&#39;s TMSPC-8i to measure thermal stability of DNA/RNAs</li>
<li>Learn about the convenience of using Shimadzu&#39;s BioSpec-nano for nucleic acid quantitation down to 1µL</li>
<li>Learn how Shimadzu&#39;s MultiNA system can automate gel electrophoresis with improved reproducibility and sensitivity</li>
</ul>
<blockquote>
Presenter: Tan Qi An (Application Specialist - Spectroscopy, Shimadzu - Asia Pacific Pte Ltd)
</blockquote>
<blockquote>
Qi An is a highly skilled professional with a bachelor&#39;s degree in Chemistry and Biological Chemistry from Nanyang Technological University, Singapore. His passion for food science led him to pursue a concurrent second major in Food Science and Technology from Wageningen University. With over two years of experience as an Application Specialist for spectroscopy and TOC instruments at Shimadzu Asia Pacific, Qi An has successfully conducted pre-sales demonstrations, sample analysis, and provided application support across diverse industries. His expertise and commitment to delivering high-quality solutions make him a valuable asset to the field of analytical chemistry.
</blockquote>
<blockquote>
Presenter: Naatasha Isahak, PhD (Market Specialist - Clinical and Forensics, Shimadzu Asia Pacific)
</blockquote>
<blockquote>
Naatasha Isahak is a Product Specialist for MALDI and Life Sciences Products from Shimadzu Asia Pacific Pte Ltd. She has received her PhD from the University of Sydney (Chemistry) working on surface initiated polymerisation on silica nanoparticles using RAFT polymerisation and bioorthogonal conjugation of peptides using Native Chemical Ligation. She then spent 5 years working on developing platforms for stem cells and organoids characterization that included working with microfluidic devices and helical polymers. Naatasha joined Shimadzu in 2022 to expand her experiences to MALDI characterization on materials and biological samples.
</blockquote>

Shimadzu: Discover the Building Blocks of Life – DNA and RNA Analysis Solutions

Discover the Building Blocks of Life – DNA and RNA Analysis Solutions

Nucleic acid analysis, using UV-Vis spectroscopy and microchip electrophoresis.

DNA and RNA Analysis Solutions

UV-Vis spectroscopy is a mature technology used to analyze, characterize, and quantify pharmaceutical and biological samples such as active pharmaceutical ingredients, DNA/RNA, and proteins for many decades. The use of UV-Vis has been limited by the workflow needed to make these measurements efficiently. Recent advances in UV-Vis spectroscopy focus on enhancing lab productivity, offering ease of use, and providing multiple accessories designed specifically for application needs. Pharmaceutical and biopharmaceutical materials have become more sophisticated in life science research and the technology used for analysis should evolve too. This webinar will highlight the new Agilent Cary 3500 Flexible UV-Vis spectrophotometer and its capabilities in improving workflows in the pharmaceutical industry.
<h5>Key Learning Objectives:</h5>
<ul>
<li>Use of the double beam Cary 3500 Flexible UV-Vis spectrophotometer for analyzing liquid and solid samples</li>
<li>See how wide linear dynamic range allows direct measurement of highly absorbing samples, minimizing sample prep time and increasing efficiency and accuracy.</li>
<li>Use of a variable pathlength cell holder to measure impurities in ethanol as outlined in pharmacopeias (UPS, EP, and JP)</li>
<li>Use of a solid sample accessory kit to determine spectral transmission measurements of plastic pharmaceutical containers in accordance with USP &lt;671&gt;.</li>
</ul>
<h5>Who Should Attend:</h5>
<ul>
<li>Pharma/biopharma QA/QC laboratory analysts and laboratory managers</li>
<li>Chemical and Energy laboratory analysis and laboratory managers</li>
<li>Academia</li>
<li>Scientist and post-graduates</li>
</ul>
<blockquote>
Presenter: Geethika Weragoda (Application Scientist, Agilent Technologies Australia Pty Ltd)
</blockquote>

C&EN: Improve Your Pharmaceutical Workflows with Innovative UV-Vis Spectroscopy

Improve Your Pharmaceutical Workflows with Innovative UV-Vis Spectroscopy

This webinar will highlight the new Agilent Cary 3500 Flexible UV-Vis spectrophotometer.

Pharmaceutical Workflows with UV-Vis Spectroscopy

<h5>The Problem</h5>When working with lipid nanoparticles, knowing which candidates are your best bets is key, so getting insights on your RNA yield and encapsulation efficiency are crucial to make sure you know which formulations and processes are the real lookers. The only catch is most methods are fluorescent dye-based assays, that need multiple sets of calibration curves, painful pipetting, and take up tons of your time.<h5>The Solution</h5>When you analyze your particles with Stunner, you’re not just getting your particle size and PDI using our new rotating angle dynamic light scattering (RADLS), you’re also scoring a complete quantification of the RNA in your sample from just 2 µL of sample. All this without the pricey reagents, dilutions, calibrations, and wasted time that comes with standard assays - plus there’s no fiddling with bubble forming surfactants to mess up your reads.<h5>The Proof</h5>In this seminar, we’ll cover a range of different cargoes and formulations to show you how Stunner fits right into any part of your workflow from RNA stock quality all the way through your final QC – we’ll even show you a hybrid method to quickly assess your EE%!Come see how Stunner can cut the headache of old timey methods and save you time, sample, and hassle in your daily LNP workflows.<blockquote>Presenter: Nelis Denys (Product Manager, Unagi, Unchained Labs)Presenter:&nbsp;Alex Kerr (Senior Applications Scientist, Unchained Labs)</blockquote>

Unchained Labs: Skip the mess with fast LNP payload quant on Stunner

Skip the mess with fast LNP payload quant on Stunner

We’ll cover a range of different cargoes and formulations to show you how Stunner fits right into any part of your workflow

ICPMS webinars focusing on UV-Vis - page 5