Labs&nbsp;that rely on helium gas are&nbsp;facing a major crisis…unless they have LECO instruments.&nbsp;Due to the military conflict in the Middle East, Qatar’s Ras Laffan Industrial City,&nbsp;the world’s largest helium production hub, providing one-third of the world’s helium,&nbsp;has&nbsp;shut down operations.&nbsp;To make matters worse,&nbsp;the Strait of Hormuz,&nbsp;the shipping lane used to&nbsp;export helium, has also been closed,&nbsp;meaning&nbsp;even pre-filled helium containers are stuck&nbsp;with&nbsp;no&nbsp;viable&nbsp;route to customers.&nbsp;Naturally,&nbsp;the price&nbsp;of helium has now risen&nbsp;dramatically;&nbsp;most spot prices have doubled.&nbsp;A&nbsp;critical&nbsp;scarcity&nbsp;issue&nbsp;is looming as&nbsp;the world must now&nbsp;operate&nbsp;on&nbsp;roughly 5.2&nbsp;million cubic meters&nbsp;per&nbsp;month&nbsp;less of helium.&nbsp;<h3>Why Helium&nbsp;Cost and Supply&nbsp;Matters&nbsp;to Labs&nbsp;</h3>Although many people may recognize helium&nbsp;as the gas that fills party balloons,&nbsp;it&nbsp;plays a&nbsp;critical&nbsp;role in much&nbsp;more serious&nbsp;matters.&nbsp;Helium&nbsp;has&nbsp;unique properties, like an extremely low boiling point, inertness, and high thermal conductivity, which&nbsp;makes&nbsp;it indispensable in several high-tech applications.&nbsp;&nbsp;For example, research labs&nbsp;may use helium as a&nbsp;carrier&nbsp;gas&nbsp;when performing&nbsp;elemental analyses or&nbsp;gas chromatography-mass spectrometry, which is used&nbsp;to&nbsp;separate and&nbsp;identify&nbsp;chemical compounds in samples.&nbsp;But research labs&nbsp;are&nbsp;often&nbsp;government-funded and run under strict budgets,&nbsp;so&nbsp;the price hike&nbsp;on&nbsp;helium could&nbsp;mean labs have to&nbsp;pause&nbsp;their research until everything falls back&nbsp;under control,&nbsp;which could be months or longer.&nbsp;Even well-funded labs could suffer if the supply is simply too stretched to&nbsp;equip&nbsp;the lab with&nbsp;what&nbsp;they need, as medical uses are given top priority.&nbsp;This could have a serious impact on accuracy and compliance with regulated methods.&nbsp;&nbsp;<h3>The Consequences&nbsp;Reach Farther&nbsp;</h3>When helium becomes unavailable or prohibitively expensive, the ripple effects are immediate and far-reaching. It affects more than&nbsp;just&nbsp;balloons and research labs:&nbsp;<ul><li>Delayed Medical Diagnostics: MRI machines, which rely on helium to cool their superconducting magnets, may be taken offline, delaying critical scans.&nbsp;</li><li>Semiconductor Bottlenecks: Chip shortages could worsen,&nbsp;impacting&nbsp;everything from smartphones to electric vehicles and AI infrastructure.&nbsp;</li><li>Industrial Disruption: Welding, aerospace, and fiber optics manufacturing&nbsp;face rising costs and potential production halts.&nbsp;</li></ul><h3>LECO’s Solution: Instruments That&nbsp;Don’t&nbsp;Rely on Helium&nbsp;&nbsp;</h3>Amidst this pending&nbsp;crisis, LECO offers a practical and forward-thinking solution.&nbsp;This marks the 5th&nbsp;major helium supply crisis since 2006,&nbsp;and&nbsp;it’s&nbsp;likely there will be more after this. Helium&nbsp;supply is concentrated&nbsp;to&nbsp;just a few regions, meaning that any time there is a disruption to one of these, it can create a large effect on the industry.&nbsp;That’s&nbsp;why we designed our innovative analytical instruments&nbsp;to&nbsp;operate&nbsp;using alternative carrier gases.&nbsp;&nbsp;Depending on the instrument, alternative gases&nbsp;such as nitrogen,&nbsp;argon,&nbsp;or hydrogen may be used in place of helium. These gases are&nbsp;abundant, cost-effective, and&nbsp;less prone&nbsp;to the geopolitical volatility that plagues helium supply chains.&nbsp;&nbsp;LECO’s helium-free&nbsp;options&nbsp;ensure that operations stay online, efficient, and future-proof&nbsp;in a world where helium is becoming increasingly scarce and expensive.&nbsp;This flexibility is no longer a luxury—it’s&nbsp;a necessity.&nbsp;If your lab or facility is feeling the pressure of helium scarcity, now is the time to explore alternatives.&nbsp;This&nbsp;isn’t&nbsp;the first helium shortage, and it&nbsp;won’t&nbsp;be the last.&nbsp;Is your lab prepared?<h3>LECO Instruments Supporting Non-Helium Carrier Gases&nbsp;</h3><h4><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/36">Pegasus BT</a> (Bench-Top GC–TOFMS, <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/37">incl. BT 4D</a>)</h4><ul><li>Supported Carrier Gases: Helium or Hydrogen</li><li>Notes on Usage / Limitations: Supports H₂ as GC carrier with a retrofit kit for safety. Performance on hydrogen is on par with helium – the Pegasus BT series meets its full sensitivity specs with either gas.</li><li>App Note: “<a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/PEGBT_TEA_TREE_ESSENTIAL_OIL_HYDROGEN_CARRIER_GAS_203_821_651_95c7a05807/PEGBT_TEA_TREE_ESSENTIAL_OIL_HYDROGEN_CARRIER_GAS_203-821-651.pdf">A Rapid, Robust and Sensitive Analysis of Tea Tree Essential Oil Quality by GC-TOFMS with Hydrogen as Carrier Gas</a>”</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_Pegasus_BT_2_bc8a8d0505.jpg" alt="LECO: Pegasus BT" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_Pegasus_BT_2_bc8a8d0505.jpg 238w," sizes="100vw" width="932" height="612"><h4><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/1097">Pegasus BTX</a> (Next-gen BT, incl. BTX 4D)</h4><ul><li>Supported Carrier Gases: Helium or Hydrogen</li><li>Notes on Usage / Limitations: Designed for seamless helium-to-hydrogen use. The Pegasus BTX series maintains trace-level sensitivity with either helium or hydrogen carrier gas, a rare capability in GC–MS. No hardware changes needed beyond standard setup.&nbsp;</li><li>App Note: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/PEGBTX_GINGER_OIL_HYDROGEN_CARRIER_GAS_203_821_694_1685d36546.pdf">“Ginger Oil Analysis and Grade Differentiation with Pegasus BTX Using Hydrogen Carrier Gas”</a></li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_LECO_PEGASUS_BTX_GC_TOFMS_cover_image_34704e689d.jpg" alt="LECO: Pegasus BTX" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_LECO_PEGASUS_BTX_GC_TOFMS_cover_image_34704e689d.jpg 235w," sizes="100vw" width="416" height="276"><h4><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/38">Pegasus&nbsp;HRT</a>&nbsp;(High-Resolution TOF-MS,<a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/39"> incl. 4D</a>)</h4><ul><li>Supported Carrier Gases: Helium or Hydrogen</li><li>Notes on Usage / Limitations: High-resolution GC–TOFMS systems support H₂ as a carrier gas as well as He.&nbsp;Note:&nbsp;Strict safety protocols apply due to&nbsp;hydrogen’s&nbsp;flammability. Hydrogen use is not recommended in instruments/configurations where gas could accumulate (e.g.&nbsp;very long, vertical&nbsp;flight tubes), but LECO’s HRT instruments&nbsp;utilize&nbsp;Folded Flight Path technology, which&nbsp;eliminates&nbsp;this concern.&nbsp;</li><li>App Note: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/GC_MS_Analysis_Hydrogen_Carrier_Gas_MMS_Ion_Source_HRT_G_Cx_GC_TOFMS_SA_ASMS_23_LPSS_310_6247a1baaf/GC-MS_Analysis_Hydrogen_Carrier_Gas_MMS_Ion_Source_HRT-GCxGC-TOFMS_SA_ASMS23_LPSS-310.pdf">“GC–MS Analysis with Hydrogen Carrier Gas on GC×GC-HRTOFMS (MMS Ion Source)”</a></li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_Pegasus_GC_HRT_831fcb6d1e.jpg" alt="LECO: Pegasus&nbsp;HRT" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_Pegasus_GC_HRT_831fcb6d1e.jpg 226w," sizes="100vw" width="3600" height="2487"><h4><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1884">LECO 828 Series</a> (Nitrogen/Protein/Carbon/Hydrogen)</h4><ul><li>Supported Carrier Gases: Helium or Argon&nbsp;</li><li>Notes on Usage / Limitations: The LECO 828 Series&nbsp;supports&nbsp;argon as an alternative&nbsp;carrier gas&nbsp;to helium. Helium provides higher TCD sensitivity (important for low-N samples),&nbsp;whereas&nbsp;argon operation raises the nitrogen detection limit and slightly reduces low-range precision. Switching gas type simply requires updating the method and flow settings (no hardware change&nbsp;required).</li><li>App Note: <a target="_blank" rel="noopener noreferrer" href="https://www.leco.com/documents/203-821-665/?_gl=1*1d6stb6*_up*MQ..*_ga*MTMwMjg4MTUxNC4xNzc2MTAzOTU0*_ga_K8NYKVEKHY*czE3NzYxMDM5NTQkbzEkZzAkdDE3NzYxMDM5NTQkajYwJGwwJGg0NTY2NjUwNjk.*_ga_KRDSR1XM7X*czE3NzYxMDM5NTQkbzEkZzAkdDE3NzYxMDM5NTQkajYwJGwwJGgw">“Carbon, Hydrogen, and Nitrogen in Biomass using CHN828”</a>&nbsp;</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_rada_828_Makroanalyza_spalovanim_pro_analyzator_uhliku_vodiku_dusiku_a_bilkovin_e86acd897e.jpg" alt="LECO 828 Series" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_rada_828_Makroanalyza_spalovanim_pro_analyzator_uhliku_vodiku_dusiku_a_bilkovin_e86acd897e.jpg 137w," sizes="100vw" width="454" height="516"><h4><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1885">LECO 928 Series</a> (Nitrogen/Protein/Carbon/Sulfur)</h4><ul><li>Supported Carrier Gases: Helium or Argon&nbsp;</li><li>Notes on Usage / Limitations: The LECO&nbsp;928 Series&nbsp;also&nbsp;supports&nbsp;argon carrier gas as an alternative to helium. Helium use gives the best sensitivity and lowest detection limits for nitrogen, while argon use increases analysis time slightly and raises the nitrogen detection limit (due to the smaller thermal conductivity difference). The 928-series instruments have built-in&nbsp;settings for either gas; when switching, users adjust flow&nbsp;and select&nbsp;the appropriate carrier gas&nbsp;in the system settings. Users also have the option to select&nbsp;a larger aliquot loop&nbsp;in the analysis method&nbsp;to improve&nbsp;precision.&nbsp;</li><li>App Note: <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/CN_928_CN_CARBON_BLACK_GRAPHITE_203_821_684_c2224fa8be.pdf">“Determination of Carbon and Nitrogen in Carbon Black and Graphite”</a></li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_rada_928_Stanoveni_makrohodnot_pomoci_spalovani_3_74de99f8e5.jpg" alt="LECO 928 Series" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_rada_928_Stanoveni_makrohodnot_pomoci_spalovani_3_74de99f8e5.jpg 216w," sizes="100vw" width="711" height="513"><h4><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1880">736</a>/<a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1882">836</a> Series&nbsp;(Inert Gas Fusion O2/N2&nbsp;/H2&nbsp;&nbsp;analyzers)</h4><ul><li>Supported Carrier Gases: Helium or Argon&nbsp;</li><li>Notes on Usage / Limitations: LECO’s inert gas fusion analyzers for oxygen and nitrogen in inorganic materials (e.g.&nbsp;models ON736, ON836) traditionally use helium as the carrier for the TCD measuring N2. These systems can run on argon as well, provided the appropriate He/Ar&nbsp;dual-purpose TCD is installed. Switching from He to&nbsp;Ar&nbsp;in these instruments is a one-time setup change;&nbsp;both gases are supported in the software (selectable “Gas Type” setting).&nbsp;When using argon, the furnace runs hotter&nbsp;and produces more soot, so maintenance (filter changes, cleaning)&nbsp;becomes more frequent.&nbsp;Low-level nitrogen precision is also slightly&nbsp;lessened&nbsp;with argon.&nbsp;&nbsp;</li><li>App Note: <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/ONH_836_O_N_H_IRON_STEEL_NICKEL_COBALT_ALLOYS_COMPARISON_203_821_601_3c9836f4b4.pdf">“Determination of Oxygen, Nitrogen, and Hydrogen in Iron, Steel, Nickel-base, and Cobalt-base Alloys: Comparison of Analytical Performance Between Argon and Helium Carrier”&nbsp;</a></li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_rada_736_Analyza_kysliku_a_dusiku_roztavenim_vzorku_v_inertnim_plynu_3_0ec033bbbb.jpg" alt="LECO 736 Series" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_rada_736_Analyza_kysliku_a_dusiku_roztavenim_vzorku_v_inertnim_plynu_3_0ec033bbbb.jpg 151w," sizes="100vw" width="825" height="852"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_rada_836_Analyza_prvku_pro_detekci_kysliku_dusiku_a_vodiku_5_8011397ce6.jpg" alt="LECO 836 Series" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_rada_836_Analyza_prvku_pro_detekci_kysliku_dusiku_a_vodiku_5_8011397ce6.jpg 134w," sizes="100vw" width="657" height="764"><h4><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1850">DH603&nbsp;Hydrogen Determinator</a></h4><ul><li>Supported Carrier Gases: Nitrogen (carrier), Helium (calibration gas)&nbsp;</li><li>Notes on Usage / Limitations: The DH603 measures diffusible and residual hydrogen in metals by hot extraction. It does&nbsp;not use helium as a carrier&nbsp;during analysis—instead&nbsp;it uses nitrogen as the purge/carrier gas in the TCD system. A small helium dose is used only for calibration and system checks (to introduce a known H2&nbsp;quantity via He-H2&nbsp;mix). In routine operation, the furnace is purged with N2&nbsp;and any hydrogen released from the sample is carried to a TCD that&nbsp;references against&nbsp;the nitrogen background. This design avoids flammable gas in the instrument entirely.&nbsp;</li><li>App Note: <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/DH_603_H_STEEL_SAMPLES_203_821_376_68e63cfea2.pdf">“Hydrogen Determination in Steel Samples Using DH603”&nbsp;</a></li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_DH_603_Stanoveni_zbytkoveho_a_difuzniho_vodiku_horkou_extrakci_d968c7c42b.jpg" alt="LECO: DH603&nbsp;Hydrogen Determinator" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_DH_603_Stanoveni_zbytkoveho_a_difuzniho_vodiku_horkou_extrakci_d968c7c42b.jpg 237w," sizes="100vw" width="1325" height="875">

As Helium Prices Rise and Supply Shrinks, LECO Customers Have Reliable Alternatives

It is our great pleasure to invite you to attend and contribute to the 19th International Symposium on Hyphenated Techniques in Chromatograph and Separation Technology (HTC-19), which will take place from May 26 to 29 in Leuven, Belgium.The HTC symposium series started in 1990 and is the ideal meeting place for scientists and practitioners from academia and industry and vendors to discuss and gather new insights in emerging technologies, instrumentation, workflows, and applications. Organized under the auspices of the Vrije Universiteit Brussel (VUB), the Catholic University of Leuven (KU Leuven), Ghent University (UGhent), and the Separation Science Group of the Royal Society of Chemistry (RSC), HTC-19 is expected to gather over 300 participants.<h3>Registration</h3><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://www.kuleuven.be/register/en/htc-19-19th-international-symposium-on-hyphenated-techniques-in-chromatography-and-separation-technology/step1">Register HERE</a></blockquote><h4>Registration Fee</h4><h5>Regular (From 14 March 2026)</h5><ul><li>Industry / Academic: € 775</li><li>Student: € 425</li></ul><h5>Conference dinner / Tasting Event</h5><ul><li>Participants: € 95 / € 50</li><li>Accompanying persons: € 110 / € 60</li></ul><h5>Short courses (CE, GC and GCxGC, NANOLC-MS, 2D-LC)</h5><ul><li>Academic: € 500</li><li>Industry: € 500</li><li>Students: € 350</li></ul><h5>Short course (AI MD Development)</h5><ul><li>Academic: € 250</li><li>Industry: € 250</li><li>Students: € 125</li></ul><h3>Programme</h3><h4>Plenary Spekares</h4><h5>Under pressure: bringing supercritical fluids to multi-dimensional analysis systems</h5><ul><li>Caroline West, Université d’Orléans, France<ul><li>Caroline West is a full professor in analytical chemistry at the University of Orleans, France, where she is teaching separation science. Her main scientific interests lie in fundamentals of chromatographic selectivity, both in the achiral and chiral modes, in SFC and LC. She is also applying these methods, with or without hyphenation to extraction methods and/or MS, to samples of pharmaceutical interest and natural products. She has authored about 120 papers in international peer‐reviewed journals and has presented about 120 lectures in conferences. In 2015, she received the “LC‐GC Emerging Leader in Chromatography” award. She was ranked several times among the most influential people in analytical chemistry by “The Analytical Scientist” magazine (“Top 40 under 40” 2014 &amp; 2018, “The Power List” 2019, 2020 &amp; 2021), received the Jubilee medal from the Chromatographic Society (2021) and JFK Huber Lecture award from the Austrian Society of Analytical Sciences (2025). She is also an advisory board member for several journals in separation science.</li></ul></li></ul><h5>Open Science Cheminformatics Resources Supporting Hyphenated Non-target Screening Efforts</h5><ul><li>Emma Schymanski, University of Luxembourg, Luxembourg<ul><li>Professor Emma Schymanski is head of the Environmental Cheminformatics (ECI) group, FNR ATTRACT Fellow and special advisor to the rector for Open Science and Research Data Management. She has a double degree in Chemistry/Environmental Engineering from UWA, Perth, completed her PhD at UFZ Leipzig and postdoc at Eawag, Switzerland. Her research combines cheminformatics and computational (high resolution) mass spectrometry approaches to elucidate the unknowns in complex samples, primarily with non-target screening, and relate these to environmental causes of disease. She is involved in many collaborative efforts, with &gt;16,000 citations, &gt;100 publications and a book. An advocate for FAIR and open science, she is involved in several European and worldwide activities to improve the exchange of data, information and ideas between scientists, including the NORMAN Suspect List Exchange, MassBank, MetFrag, PubChemLite for Exposomics, the PubChem PFAS Tree, patRoon, ShinyTPs and the Chemical Stripes.</li></ul></li></ul><h5>The challenges of scale for meaningful environmental research</h5><ul><li>Leon Barron, Imperial College London, United Kingdom<ul><li>Professor Leon Barron leads the Emerging Chemical Contaminants group at Imperial College London. His research aims to further our understanding of complex chemical exposures on environmental and public health. He gained his PhD in 2005 from Dublin City University and in 2009 moved to King’s College London as an academic in Forensic Science until 2020. He moved to Imperial in 2020 and was recently promoted to full professor of Analytical and Environmental Sciences in 2025. He has pioneered several (bio)analytical methodologies especially the development and integration novel passive sampling tools, liquid chromatography-mass spectrometry methods and predictive machine learning for contaminant identification, monitoring and risk assessment. He is a Fellow of the Royal Society of Chemistry and is the current Chair of its Separation Science Interest Group. His work has been recognised particularly for its large-scale applicability including in national and international monitoring campaigns in partnership with academia, government, industry and the general public.</li></ul></li></ul><h5>Hyphenated methods in chromatography: Innovations realised and challenges remaining</h5><ul><li>Hans-Gerd Janssen, Unilever, The Netherlands<ul><li>Prof. Hans-Gerd Janssen obtained his MSc and PhD degree in analytical chemistry from the Eindhoven University of Technology. After having worked at this university for another 8 years as an assistant/associate professor, he moved to Unilever R&amp;D in 1999 and currently holds the position of science leader Food Compositional Analysis. From 2004 to 2019 he was a part-time professor at the University of Amsterdam at the chair ‘(bio-)macromolecular separations’. In 2019 he moved to Wageningen University where he now holds a part-time professor position in ‘recognition-based analytical chemistry’. Prof. Janssen has published more than 230 papers including six patents and seven book chapters. He is a member of the editorial advisory board of several scientific journals. He has been, or is, a member of the board of the Analytical Chemistry division of the Dutch Chemical Society and of the working group Separation Methods. He also is a member of the scientific or organizing committee of several symposia. Prof. Janssen was awarded the 2020 GC×GC scientific achievement award in recognition of his contribution to the field. In 2023 he was awarded the H.J. Dutton Award from the American Oil Chemist’s Society. In his research he focuses on the development of chromatographic methods and theories for the reliable, rapid and automated analysis of complex samples. Much of his work was on edible oils and fats, but also other food related samples including packaging materials and food processing got his attention. More recently his work focusses on food flavour analysis and understanding sensory perception from detailed chemical analysis.</li></ul></li></ul><h5>Delicious Science: A Chemical Journey Through the Kitchen</h5><ul><li>Peter Van Broeck, WM-Lightning B.V., Belgium<ul><li>Dr. Peter Van Broeck has more than 30 years of experience in analytical chemistry, process control, and technological innovation within the pharmaceutical and chemical industry. Since 2023, he has been Managing Director of WM-Lightning B.V., a consultancy firm specialized in innovation, interim management, and strategic support. He spent a significant part of his career at Johnson &amp; Johnson, where he held leadership roles in Analytical Development and Chemical Process Control. As Scientific Director, he was end-to-end responsible for the analytical strategy within continuous manufacturing, the implementation of Process Analytical Technology (PAT), and the introduction of new analytical technologies. He developed extensive international academic and industry networks and represented the organization in various innovation programs and conferences. Earlier, Dr. Van Broeck led the Chemical Process Control Lab, where he drove the global adoption of PAT. At Amylum NV and BetzDearborn Inc., he focused on analytical method development, laboratory setup, and the introduction of advanced techniques such as HT-GPC, NIR and hyphenated GC and HPLC techniques. He also served as a Guest Professor at Hasselt University, teaching Industrial Chemistry to Business Engineering students. Beyond his scientific career, Dr. Van Broeck has a long-standing passion for wine, gastronomy, and the chemistry of flavor. Building on early academic and R&amp;D experience in food analytics, he actively explores the intersection of taste, chemistry, and sensory experience, and is frequently invited as a speaker on topics such as food pairing and the science of brewing and winemaking.</li></ul></li></ul><h5>Shaken, not stirred – James Bond in the spotlight of physics</h5><ul><li>Metin Tolan, Faculty of Physics, TU Dortmund University, Germany<ul><li>Main areas of research: Investigation of the interfacial behavior of so-called “soft matter” (polymers, liquids, biomaterials), phase diagrams and stability of proteins, use of synchrotron radiation for materials research in general and further development of investigation methods, more than 200 publications in refereed journalsProfessional career: Since April 2025: Professor of Experimental Physics, Faculty of Physics, TU Dortmund University 2021–2025: President of Georg August University of Göttingen (on leave from TU Dortmund University) 2008–2020: Vice Rector for Research (3 years), for Studies (5 years), for Finance (4 years) at TU Dortmund University, permanent representative of the Rector 2003: Admitted as a full member of the North Rhine-Westphalian Academy of Sciences and Arts Since 2001: full professorship (C4) for experimental physics at TU Dortmund University. Chair of Experimental Physics I 1998 – 2001 Habilitation in experimental physics. Lecturer at Christian Albrechts University of Kiel 1994 – 1998: Research stays in the USA at Brookhaven National Laboratory (1994), Exxon Research Laboratories (1994), State University of New York at Stony Brook (1995 and 1998) and Argonne National Laboratory (1996 and 1997) 1990–1993: Research assistant, Institute for Experimental Physics, Christian Albrechts University of Kiel. Doctorate in physics (dissertation: “X-ray scattering on laterally structured surfaces – experiment and theory”) 1984–1989: Studied physics with a minor in mathematics, Christian Albrechts University of Kiel. Diploma in mathematical physics Awards: 2024 Culture Prize of the Eduard Rhein Foundation 2018 Awarded the Badge of Honor of the German Physical Society 2017 Robert Wichard Pohl Prize of the German Physical Society for outstanding contributions to physics 2013 Communicator Prize of the DFG and the Stifterverband der Deutschen Wissenschaft 2010 Awarded the Silver Badge of Honor for special services to the DESY Research Center in Hamburg 2010 Professor of the Year elected by magazine “UNICUM Beruf” in the field of natural sciences and medicinePopular Books: 5 books published, among them “Shaken, not stirred! – James Bond in the Spotlight of Physics” Springer (2020) (in German: “Geschüttelt, nicht gerührt! – James Bond im Visier der Physik”, Piper 2008)</li></ul></li></ul>

Plenary speakers at the 19th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-19)

Sabina Cerulová originally planned to study veterinary medicine, but coincidence, the covid‑19 pandemic, and her bachelor’s project led her to research at RECETOX. Today, as a PhD student, she studies a rare genetic mutation responsible for severe symptoms in a specific patient, and she works with animal models, microbiome, and advanced imaging methods. What motivates her in science is the variety of work, the opportunity to constantly learn, and the hope that her work will one day help real people.&nbsp;<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/RECETOX_MUNI_Ph_D_studentka_Sabina_Cerulova_Veda_da_strasne_moc_ale_strasne_moc_si_taky_vezme_Musi_vas_to_bavit_2_1ad2382856.jpeg" alt="RECETOX-MUNI: PhD student Sabina Cerulová: Science gives you so much, but it also takes a lot — you really must enjoy it" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_RECETOX_MUNI_Ph_D_studentka_Sabina_Cerulova_Veda_da_strasne_moc_ale_strasne_moc_si_taky_vezme_Musi_vas_to_bavit_2_1ad2382856.jpeg 117w," sizes="100vw" width="738" height="984"><h5>How did you get into studying biochemistry and later into research at RECETOX?</h5>I went to grammar school and for a long time I had no idea what exactly I wanted to do. It wasn’t until my final year that I realized I was drawn to veterinary medicine. But high school was wild. I had good grades, but I didn’t study much, and I thought the entrance exams would be similar. I was very wrong.&nbsp;I applied to veterinary schools and biochemistry at the Faculty of Science, where I was luckily accepted, so I enrolled. Originally, I planned to transfer to veterinary medicine the next year, but then covid came, and admissions were based on high school grades, usually only straight A’s, so I didn’t get in.&nbsp;In my second year, I started working on my bachelor’s thesis, and something just clicked. I got better at it, I understood more, my grades improved, and I decided to finish my bachelor’s degree. And then I was offered an amazing project.&nbsp;<h5>Before we get to that project, what did you work on in your bachelor’s thesis</h5>My bachelor’s thesis focused on analyzing the microbiome in the root canal of teeth in patients with apical periodontitis. I worked on it here at RECETOX under Associate Professor Petra Bořilová Linhartová. It was incredibly interesting — completely new work, new analyses. Because of covid, we had fewer lab classes, but I still really enjoyed it. After my bachelor’s, I received an offer from my supervisor, who knew I was interested in animals and veterinary science. For my thesis, she offered me the project we’ve already mentioned, which we work on in collaboration with the Institute of Histology and Embryology, in Associate Professor Křivánek’s group. They work with animal models, mainly mice, and study the effect of a genetic mutation found in a specific patient.&nbsp;<h5>Why were you so drawn to animals? Have you ever considered studying medicine?&nbsp;</h5>I’ve been close to animals since I was little. I used to ride horses, and at home we had hamsters, chinchillas, cats, and dogs. Everyone asked me why I didn’t go into medicine, but I guess I just like animals more than people (laughs). I liked the idea of having my own veterinary practice and being close to them.&nbsp;Biochemistry was more of a backup plan; I didn’t really know what I was getting into. And I don’t regret it. Veterinary medicine will probably always be a dream, but I’m glad I stayed here.&nbsp;<h5>Could you describe the project in more detail? If I understand correctly, you’re continuing the same topic in your dissertation.&nbsp;</h5>Yes, that's right. Our research group collaborates with a hospital, which provided us with results from a patient who had numerous pathological findings since childhood: bone lesions, shortened tooth roots, enamel hypomineralization, joint pain, high phosphate levels in the blood.&nbsp;Whole‑exome sequencing was performed, and a very rare mutation was identified in the gene that I study. In collaboration with other institutions, we created a mouse with the same point of mutation. It underwent phenotyping screening, and its symptoms were very similar to the patient’s. That was a huge success. Now we’re trying to further characterize the model and, in the future, test treatment options on it — diets, DNA modification, anything that could help not only her but also other patients with similar symptoms.&nbsp;<h5>Do you work only with that one mutation, or with other models as well?</h5>Primarily, I focus on one specific point of mutation, but we also worked with knockout mice where the gene is completely switched off. The results were quite variable, so we now study both lines. Thanks to our collaborations, we also have access to data from other mouse models with mutations in genes closely associated with hyperphosphatemia, which helps us put our results into a broader context.&nbsp;<h5>Are you planning to study additional patients as well?</h5>Yes. We want to publish a paper on additional patients, especially those on dialysis, and examine their phosphate levels and potential genetic modifications. Phosphate is not routinely tested, so similar disorders may be hidden. We’d like to find out whether their problems could be related to this gene and thus make our project applicable to a larger group of patients.&nbsp;<h5>Do you use imaging methods? With what goal?</h5>Yes. We wanted something non‑invasive, because microCT requires euthanizing the mice. In collaboration with the core facility, we’re testing MRI to observe manifestations of the mutation over time — in bones, soft tissues, kidneys. We obtained a grant for this, currently for one year. We need to observe progression, and then we can apply for further funding.&nbsp;<h5>What surprised you most about working with animal models?&nbsp;</h5>The time. Everything takes so long. Mice are living organisms, sometimes they’re born and then eat each other. It’s unpredictable. And we got our first shock when we were expecting offspring and nothing happened. Only later we found out that males with this mutation are infertile. As an animal lover, I cried over the first mouse I lost. But then you remind yourself that you're doing this to help patients. And you look for ways to use as few mice as possible.&nbsp;<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/RECETOX_MUNI_Ph_D_studentka_Sabina_Cerulova_Veda_da_strasne_moc_ale_strasne_moc_si_taky_vezme_Musi_vas_to_bavit_1_787855e117.jpeg" alt="RECETOX-MUNI: PhD student Sabina Cerulová: Science gives you so much, but it also takes a lot — you really must enjoy it" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_RECETOX_MUNI_Ph_D_studentka_Sabina_Cerulova_Veda_da_strasne_moc_ale_strasne_moc_si_taky_vezme_Musi_vas_to_bavit_1_787855e117.jpeg 117w," sizes="100vw" width="450" height="600"><h5>Why don’t you use vitro approaches instead, such as testing outside a living organism?&nbsp;</h5>Because of speed and complexity. Mice reproduce quickly, live for about two years, and share 99% of their genes with humans. Using cells would be much slower, and we wouldn’t see the full picture of how the organism behaves.&nbsp;<h5>What do you enjoy most about the work?</h5>The variety. That I can tailor my day to what I have the capacity for. Sometimes I prepare samples for sequencing, sometimes I do analyses, sometimes I teach. I enjoy constantly learning and the diversity of tasks.&nbsp;<h5>What is the hardest part of PhD studies for you?</h5>Time management. I’m not good at it, and I’m very grateful to my supervisor, who helps me stay on track. And also, not losing myself in the work — I need to have a personal life. I do this because I enjoy it, but I don’t want to burn out.&nbsp;<h5>How do you view working with students?</h5>I enjoy it, but it’s demanding. Sometimes students mistake me for one of them (laughs), because I look young. And they’re very motivated — sometimes I feel like they know more than I do. But it has taught me a lot about patience and confidence. I really enjoy taking lectures.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/RECETOX_MUNI_Ph_D_studentka_Sabina_Cerulova_Veda_da_strasne_moc_ale_strasne_moc_si_taky_vezme_Musi_vas_to_bavit_3_f7b11b8efa.jpeg" alt="RECETOX-MUNI: PhD student Sabina Cerulová: Science gives you so much, but it also takes a lot — you really must enjoy it" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_RECETOX_MUNI_Ph_D_studentka_Sabina_Cerulova_Veda_da_strasne_moc_ale_strasne_moc_si_taky_vezme_Musi_vas_to_bavit_3_f7b11b8efa.jpeg 156w," sizes="100vw" width="450" height="450"><h5>What are you most proud of in your scientific journey so far?</h5>My progress. I never imagined myself in academia. Looking back, I’m grateful to the consultants on my bachelor’s thesis for their patience. Changing my approach and discovering that I enjoy it has moved me forward the most. I’m not focused on one specific result but on personal growth.&nbsp;<h5>What motivates you to keep going?&nbsp;</h5>The idea that one day it will work out. I try to stay positive, even though some days are tough and nothing goes according to plan.&nbsp;<h5>Do you also engage in science outreach?</h5>Yes. We do a lot, especially for children. I recently visited my hometown, Karviná. We have third graders, ninth graders… It’s great; the kids are enthusiastic. Outreaching is extremely important — showing that science is fun and needed everywhere.&nbsp;<h5>And what is next after the PhD?</h5>I don’t know. Maybe another PhD (laughs). But I certainly want to stay in science.<h5>What advice would you give to young people considering a scientific career?</h5>You must enjoy it. Science gives you so much, but it takes a lot as well. You must be passionate about it and find a topic that’s truly yours.

PhD student Sabina Cerulová: Science gives you so much, but it also takes a lot — you really must enjoy it

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RECETOX (Research Centre for Toxic Compounds in the Environment) is an independent department of the Faculty of Science of Masaryk University in Brno, which has been established in 1983. RECETOX is focused on the research and education in cross-cutting area of Environment and Health. It addresses interactions among chemicals, environment, and biological systems, including consequences at local, regional, and global levels.

RECETOX - Centrum pro výzkum toxických látek v prostředí

In 1936, the Laboratory Equipment Company introduced the first rapid carbon determinator for the American iron and steel industry.  Today, almost 80 years later, LECO is recognized globally as a leader in the development of high-quality analytical instrumentation, mass spectrometers, comprehensive two-dimensional chromatography, metallography & optical equipment as well as consumables.

LECO

The HTC symposium series started in 1990 and is the ideal meeting place for scientists and practitioners from academia and industry and vendors to discuss and gather new insights in emerging technologies, instrumentation, workflows, and applications. Organized under the auspices of the Vrije Universiteit Brussel (VUB), the Catholic University of Leuven (KU Leuven), Ghent University (UGhent), and the Separation Science Group of the Royal Society of Chemistry (RSC), HTC-19 is expected to gather over 300 participants.

International Symposium on Hyphenated Techniques in Chromatography and Separation Technology

DataApex Clarity Offline Chromatography Software

Clarity Offline allows users to import previously acquired data and to evaluate and prepare methods in regulated environment.

Clarity Offline allows users to import previously acquired data and to evaluate and prepare methods. This version cannot acquire data, but it can share data or even directly access (through LAN) projects of the <a href="https://lcms.labrulez.com/products/999">Clarity</a> and Clarity Lite software. With Clarity Offline users are able to work with acquired data on additional computers in the lab or at home. The software works with the same files and provides the same outputs (printing and exporting) as Clarity and Clarity Lite.
Clarity Offline is intended for use as additional software that supplements Clarity and Clarity Lite. It can also be used to evaluate data from other manufacturers&#39; CDS.
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Ask for <a href="https://www.dataapex.com/product/clarity-demo">Clarity Demo version</a> which allows you to get your hands on software before purchase
</blockquote>
<h3>Main features</h3>
<ul>
<li>21 CFR Part 11 compliance: Clarity Offline contains all functions (Electronic Signatures, User Accounts, Audit Trail, etc.) for compliance with the 21 CFR Part 11 directive of the FDA. Clarity Offline can be used for evaluation in regulated environments.
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<li>Networked Solution: Clarity Offline can access files of Clarity and Clarity Lite installed on networked computers. This enables evaluation of chromatograms, development of new methods, and printing reports on additional computers in the laboratory.
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<li>Education: An additional field of use is in education. Students can process chromatograms that have been acquired from Clarity connected to a chromatograph using their Clarity Offline license. Thus they do not need a Clarity full license just for data evaluation.
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<li>Data processing and evaluation from other chromatography software: Clarity Offline allows the import of data from other chromatography software using text or AIA import function. This allows the user to process and evaluate chromatograms acquired by other chromatography software.
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<li>Offsite computer: Clarity Offline can be installed on any Windows computer, giving you anytime access to your chromatographic data (USB hardware key is required).
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<li>Language Localizations available: Useful for non-English speakers. At the moment, there are French, German, Russian, Spanish, and Chinese localizations available in a single installation package. Simply switch to your preferred language anytime.
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<a href="https://www.dataapex.com/controls">List of supported instruments</a>
<a href="https://www.dataapex.com/product/clarity-std-compatibility">Compatible Windows OS and Hardware</a>
<a href="https://www.dataapex.com/product/clarity-21cfr-compliance">Clarity 21 CFR Part 11 compliance</a>

DataApex EA - Elemental Analysis Extension for Clarity

Using features that are specific to EA Analysis, such as Standard Table, automatic weight input from analytical balance and other improvements, EA Extension provides an interactive and automated tool for determining the Carbon, Hydrogen, Nitrogen, Oxygen, and Sulfur (CHNS-O) content of unknowns.

<h3>The extension for elemental analysis</h3>
EA Extension is a software module for Elemental Analysis. Determining the Carbon, Hydrogen, Nitrogen, Oxygen, and Sulphur (CHNS-O) content of unknowns is one of the most basic and essential needs of any chemist. It provides a simplified version of the <a href="https://icpms.labrulez.com/products/999">Clarity</a> user interface that speeds up the workflow with elemental analyzers equipped with autosamplers. Its user interface is optimized for maximum efficiency in repetitive tasks. Using features that are specific to EA Analysis, such as Standard Table, automatic weight input from analytical balance and other improvements, EA Extension provides an interactive and automated tool for determining the Carbon, Hydrogen, Nitrogen, Oxygen, and Sulfur (CHNS-O) content of unknowns.
<h3>Main features</h3>
<ul>
<li>Calibration: Simplified work with template method and calibration. One setting is shared for all samples in the same sequence.
</li>
<li>Standard Table: For your convenience, the software contains Standard Table with a list of the most commonly used calibration standards and their elemental composition.
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<li>Reporting: Clarity EA supports the printing of user defined protocols. Its configuration is saved in a report style, which defines the content and form through the printout. Protocols can be printed to the PDF file.
</li>
<li>Analytical balance: The Clarity Elemental Analysis Software provides direct interface with the analytical balance (Sartorius and Mettler). After weighing the sample, the operator presses the print key on the balance (or uses software instruction) to directly transfer the sample weight to the software sample information field thereby eliminating any possible transcription errors.
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<li>Sequence Table: Measurement is managed using the Sequence Table. The Summary Table displays results clearly. ASCII and AIA data formats can be exported or imported directly.
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<li>Database: Results can be exported in the .txt and .dbf format.
</li>
</ul>

Wiley KnowItAll Analytical Edition Software

KnowItAll by Wiley offers a comprehensive solution for identifying, analyzing, and managing analytical data, enhancing spectral analysis speed and overall lab efficiency.

Solutions for IR, MS, NMR, Raman, &amp; UV-Vis<blockquote>More information on the Wiley Science Solutions website: <a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/knowitall-analytical-edition-software/">KnowItAll Analytical Edition Software</a></blockquote><h5>Accelerate Spectral Analysis &amp; Boost Efficiency!</h5>KnowItAll by Wiley is an all-in-one solution for identifying, analyzing, and managing spectral data, streamlining lab workflows.<ul data-start="208" data-end="581" data-is-only-node="" data-is-last-node=""><li data-start="208" data-end="328">User-friendly interface with tools for processing, searching, mixture analysis, deconvolution, and reporting</li><li data-start="329" data-end="406">Patented spectral intelligence for automated, expert-driven workflows</li><li data-start="407" data-end="481">Supports multiple techniques &amp; vendor formats for full flexibility</li><li data-start="482" data-end="581" data-is-last-node="">Integrated with Wiley’s high-quality spectral databases for faster, more accurate results</li></ul><figure class="image"><img style="aspect-ratio:1922/1036;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_Wiley_Know_It_All_Analytical_Edition_Software_cover_a703599ad2/Wiley-Wiley-KnowItAll-Analytical-Edition-Software-cover.jpg" alt="Wiley: Wiley KnowItAll Analytical Edition Software" width="1922" height="1036"></figure><h4>Streamline Your Analysis with KnowItAll</h4>KnowItAll integrates all essential tools and data into a single, user-friendly platform, saving you time, optimizing workflows, and enhancing data interpretation.<h4>Compatible Data Types</h4>A vendor-neutral solution, KnowItAll supports 130+ instrument formats, ensuring seamless workflow continuity even as lab equipment evolves.<ul data-start="408" data-end="518"><li data-start="408" data-end="473">Spectroscopic Techniques: IR, MS, NIR, NMR, Raman, UV-Vis</li><li data-start="474" data-end="518">Chromatograms &amp; 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Wiley KnowItAll Quantitation

Streamline quantitation with Wiley KnowItAll—an integrated, vendor-neutral tool for GC-MS, IR, UV-Vis & more. Simplifies workflows and eliminates the need for multiple software tools.

<h4>Consolidate your software &amp; analytical workflow using KnowItAll’s integrated quantitation application</h4>Wiley’s KnowItAll now goes beyond substance identification to include quantitative analysis with an integrated, vendor-neutral tool, streamlining workflows and eliminating the need to juggle multiple software packages.The new Quantitation tool supports GC-MS, IR, Raman, UV-Vis, and GC data and offers intuitive, step-by-step processes for external/internal calibration and standard addition. By working within the familiar KnowItAll interface, it reduces training time and minimizes errors from manual tools like Excel.Available as an option in KnowItAll and included in Campus-Wide subscriptions, the tool is also VPAT 508 accessible.

Wiley SmartSpectra Raman Database Collection

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<blockquote>Unlock a broader spectrum of possibilities with Wiley SmartSpectra Databases, enhancing your chemical compound coverage to ensure more accurate and comprehensive unknown identification.More information on the Wiley Science Solutions website: <a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/solutions/technique/raman/wiley-smartspectra-raman-database-collection/">Wiley SmartSpectra Raman Database Collection</a></blockquote>The Wiley SmartSpectra Raman Database Collection offers access to 33,163 high-quality spectra for identifying unknown compounds and enhancing analytical workflows. Built on Wiley’s trusted databases, it ensures scientifically sound results.<h5>Key Benefits:</h5><ul data-start="276" data-end="738" data-is-only-node="" data-is-last-node=""><li data-start="276" data-end="352">Aids in identifying rare compounds when empirical databases lack matches</li><li data-start="353" data-end="438">Supports functional group classification, excelling with rigid structures</li><li data-start="439" data-end="530">Derived from Wiley’s high-quality empirical datasets, including Sadtler spectra</li><li data-start="531" data-end="599">Covers a wide range of compound classes for diverse applications</li><li data-start="600" data-end="689">Includes metadata (physical properties, chemical structures) for precise searches</li><li data-start="690" data-end="738" data-is-last-node="">Validated by Subject Matter Experts (SMEs)</li></ul><h4>So, just how much can the SmartSpectra database expand your compound coverage?</h4>The SmartSpectra database accelerates spectral identification by expanding chemical compound coverage. As shown, SmartSpectra data (red) extends the chemical space of the empirical dataset (blue), significantly increasing compound coverage.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_Wiley_Smart_Spectra_Raman_Database_Collection_Wiley_Raman_empirical_data_only_blue_Smart_Spectra_Raman_data_included_red_da42d540b6.jpg" alt="Wiley: Wiley SmartSpectra Raman Database Collection - Wiley Raman empirical data only (blue), SmartSpectra Raman data included (red)."><h4>Applications</h4>Use the SmartSpectra collection with empirical databases for Raman spectroscopy.<h4>Trusted Data</h4>Wiley is a leading source for spectral data. Its Sadtler databases undergo rigorous quality protocols, from data acquisition to database development. All partner data is thoroughly vetted before inclusion.<blockquote>KnowItAll is a trademark of John Wiley &amp; Sons, Inc. in certain jurisdictions.Subscription content is subject to change as data may be added or deleted from collections periodically.</blockquote><h3>Databases Included</h3>Subscription includes access to 11 databases including:<ul><li>Wiley SmartSpectra Raman Database of General Compounds (24,585 spectra)</li><li>Wiley SmartSpectra Raman Database of Biochemicals (59 spectra)</li><li>Wiley SmartSpectra Raman Database of Chemical Standards (6,458 spectra)</li><li>Wiley SmartSpectra Raman Database of Drugs (130 spectra)</li><li>Wiley SmartSpectra Raman Database of Dyes (36 spectra)</li><li>Wiley SmartSpectra Raman Database of Explosives and Hazmat Compounds (51 spectra)</li><li>Wiley SmartSpectra Raman Database of Food Related Compounds (277 spectra)</li><li>Wiley SmartSpectra Raman Database of Hydrocarbons (527 spectra)</li><li>Wiley SmartSpectra Raman Database of Industrial Compounds (439 spectra)</li><li>Wiley SmartSpectra Raman Database of Pollutants (449 spectra)</li><li>Wiley SmartSpectra Raman Database of Monomers (152 spectra)</li></ul><h3>Additional information</h3>This SmartSpectra library contains the following valuable metadata to help you narrow and refine your search results:<ul><li>Chemical Structure</li><li>Chemical Name</li><li>Exact Mass</li><li>Formula</li><li>IUPAC InChI/InChIKey</li><li>Molecular Weight</li><li>Nominal mass</li><li>Spectrum/Structure Validation Score</li></ul><h3>Compatibility</h3><ul><li>Recommended as a supplement to the KnowItAll IR Spectral Library collection of curated empirical data.</li><li>For use with KnowItAll 2024 software.</li><li>KnowItAll software is compatible with most major instrument formats. For full KnowItAll file format compatibility information, please visit <a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/compatibility/">sciencesolutions.wiley.com/compatibility</a>.</li></ul>

Linde REDLINE Pressure Regulators C 200/1 & C 200/2

REDLINE C 200 pressure regulators provide precise and stable gas control up to 6.0 purity, ideal for laboratory, analytical, and research applications.

The REDLINE C 200 series pressure regulators (models C 200/1 single-stage and C 200/2 dual-stage) are designed for precise control of non-corrosive gases with purity levels up to 6.0 (99.9999%), as well as gas mixtures containing low concentrations of corrosive components.These regulators ensure excellent pressure stability, high accuracy, and preservation of gas purity, making them ideal for demanding laboratory, analytical, and research applications.The C 200/1 single-stage version is suitable for applications with stable inlet pressure, such as gases supplied in liquid phase. The C 200/2 dual-stage version is specifically designed for systems where inlet pressure fluctuates, ensuring highly stable outlet pressure even under changing conditions.<h4>Key Features</h4><ul><li>High precision pressure regulation for analytical applications</li><li>Suitable for high-purity gases up to grade 6.0 (99.9999%)</li><li>Excellent outlet pressure stability (especially dual-stage version)</li><li>Designed to maintain gas purity and minimize contamination</li><li>Wide range of configurable outlet pressure ranges</li><li>Flexible configuration with multiple valve and purging options</li><li>Robust and reliable design for laboratory and R&amp;D environments</li></ul><h4>Technical Specifications</h4><ul><li>Inlet pressure: up to 230 bar</li><li>Outlet pressure ranges:<ul><li>C 200/1 (single-stage): 3 / 6 / 10 / 14 / 16 / 28 / 35 / 50 / 100 / 200 bar</li><li>C 200/2 (dual-stage): 1 / 3 / 6 / 10 / 14 bar</li></ul></li><li>Gas compatibility:<ul><li>Non-corrosive gases up to purity 6.0</li><li>Gas mixtures with low corrosive content</li></ul></li><li>Inlet connections:<ul><li>According to DIN 477 and gas specification</li></ul></li><li>Outlet connections:<ul><li>Compression fittings</li><li>Hose nozzles</li></ul></li></ul><h4>Available Configurations</h4><h5>Models</h5><ul><li>C 200/1 (Single-stage) Designed for applications with stable inlet pressure</li><li>C 200/2 (Dual-stage) Designed for fluctuating inlet pressure with maximum outlet stability</li></ul><h4>Optional Equipment</h4><ul><li>Shut-off valve (Type A)</li><li>Needle valve (Type B)</li><li>High-pressure side purge (Type P)</li><li>Inert/external gas purge (Type TP)</li><li>Purge manifold (Type EP)</li><li>Post-purge (Type DP – available only for C 200/2)</li></ul><h4>Applications</h4><ul><li>Laboratory gas supply systems</li><li>Analytical instrumentation (e.g., GC, LC, MS workflows)</li><li>Research and development environments</li><li>High-purity gas distribution systems</li><li>Any application requiring stable pressure and contamination-free gas delivery</li></ul>

Linde REDLINE Pressure Regulators C 300/1 & C 300/2

REDLINE C 300 pressure regulators provide precise and stable gas control up to 6.0 purity, ensuring reliability for laboratory, analytical, and research applications.

The REDLINE C 300 series pressure regulators (models C 300/1 single-stage and C 300/2 dual-stage) are designed for precise control of non-corrosive gases with purity levels up to 6.0 (99.9999%), as well as gas mixtures containing low concentrations of corrosive components.Thanks to their robust design and high-quality manufacturing, these regulators provide excellent pressure stability, accuracy, and long-term reliability. They are particularly well suited for demanding laboratory, analytical, and research applications where maintaining gas purity and consistent pressure is critical.The C 300/1 single-stage regulator is recommended for applications with relatively stable inlet pressure, such as gases supplied in liquid phase. The C 300/2 dual-stage version is intended for systems with fluctuating inlet pressure, ensuring highly stable outlet pressure and improved control under varying operating conditions.<h4>Key Features</h4><ul><li>Precise and stable pressure regulation for analytical workflows</li><li>Compatible with high-purity gases up to grade 6.0 (99.9999%)</li><li>Dual-stage version provides superior outlet pressure stability</li><li>Designed to maintain gas purity and minimize contamination risks</li><li>Wide range of adjustable outlet pressure settings</li><li>Modular design with multiple optional valve and purge configurations</li><li>High reliability for continuous laboratory and R&amp;D operation</li></ul><h4>Technical Specifications</h4><ul><li>Inlet pressure: up to 300 bar</li><li>Outlet pressure ranges:<ul><li>C 300/1 (single-stage): 3 / 6 / 10 / 14 / 16 / 28 / 35 / 50 / 100 / 200 bar</li><li>C 300/2 (dual-stage): 1 / 3 / 6 / 10 / 14 bar</li></ul></li><li>Gas compatibility:<ul><li>Non-corrosive gases up to purity 6.0</li><li>Gas mixtures with low corrosive content</li></ul></li><li>Inlet connections:<ul><li>According to DIN 477 and gas specification</li></ul></li><li>Outlet connections:<ul><li>Compression fittings</li><li>Hose nozzles</li></ul></li></ul><h4>Available Configurations</h4><h5>Models</h5><ul><li>C 300/1 (Single-stage) Designed for applications with stable inlet pressure</li><li>C 300/2 (Dual-stage) Designed for fluctuating inlet pressure with maximum outlet pressure stability</li></ul><h4>Optional Equipment</h4><ul><li>Shut-off valve (Type A)</li><li>Needle valve (Type B)</li><li>High-pressure side purge (Type P)</li><li>Inert gas purge (Type TP)</li><li>Purge manifold (Type EP)</li><li>Post-purge (Type DP – available only for C 300/2)</li></ul><h4>Applications</h4><ul><li>Analytical instrumentation (e.g., GC, LC, MS systems)</li><li>Laboratory gas supply systems</li><li>Research and development environments</li><li>High-purity gas distribution systems</li><li>Applications requiring precise pressure control and contamination-free gas delivery</li></ul>

Linde Hydrogen 3.0 – Gas Cylinder

Linde hydrogen 3.0 for industrial applications. High thermal conductivity, clean combustion, and reliable performance for welding, cutting, and energy use.

Hydrogen 3.0 from Linde is a technical-grade gas designed for a wide range of industrial applications, particularly in welding, cutting, and energy processes. Its exceptionally high thermal conductivity and excellent thermophysical properties make it highly effective for heat transfer and combustion applications.Hydrogen is a colorless, odorless, and tasteless gas that burns with an invisible flame. When combined with oxygen, it reaches very high flame temperatures. Its combustion produces no carbon or soot, ensuring clean processes without contamination.The gas is supplied in pressurized cylinders, enabling safe storage and convenient handling in industrial environments.<h4>Key Features</h4><ul><li>High thermal conductivity</li><li>Clean combustion without carbon or soot</li><li>Colorless, odorless, and tasteless</li><li>Efficient heat transfer properties</li><li>Suitable for industrial and energy applications</li><li>Supplied in pressurized cylinders</li></ul><h4>Technical Specifications</h4><ul><li>Gas: Hydrogen (H₂)</li><li>Purity: 3.0 (≥ 99.9%)</li><li>Supply form: pressurized steel cylinder (50 l, 200 bar)</li><li>Flammability: highly flammable gas</li><li>Flame: invisible, up to approx. 2,834 °C with oxygen</li><li>Properties: colorless, odorless, tasteless</li></ul><h4>Applications</h4><ul><li>Shielding gas mixtures for TIG and plasma welding</li><li>Welding of stainless steels and nickel alloys</li><li>Plasma cutting of stainless steel and aluminum</li><li>Underwater cutting (in mixture with oxygen)</li><li>Energy generation applications</li><li>Glass industry (glass melting processes)</li></ul>

Linde Hydrogen 4.0 – Gas Cylinder

Linde hydrogen 4.0 (≥99.99%) for analytical and industrial use. High purity and stable performance for GC, welding, and energy applications.

Hydrogen 4.0 from Linde is a high-purity gas (≥ 99.99%) suitable for a wide range of analytical and industrial applications. Its excellent thermophysical properties make it highly effective for combustion, heat transfer, and analytical processes.Hydrogen is a colorless, odorless, and tasteless gas that burns with an invisible flame. When combined with oxygen, it produces very high flame temperatures. Its clean combustion produces no carbon or soot, ensuring contamination-free processes.Compared to technical-grade hydrogen (3.0), hydrogen 4.0 offers higher purity, making it suitable for more demanding applications, including gas chromatography and laboratory analyses. It is supplied in pressurized cylinders for safe and convenient use.<h4>Key Features</h4><ul><li>High purity ≥ 99.99%</li><li>Excellent thermophysical properties</li><li>Clean combustion without carbon or soot</li><li>Colorless, odorless, and tasteless</li><li>Suitable for analytical and industrial applications</li><li>Supplied in pressurized gas cylinders</li></ul><h4>Technical Specifications</h4><ul><li>Gas: Hydrogen (H₂)</li><li>Purity: ≥ 99.99% (4.0)</li><li>Supply form: pressurized steel cylinder</li><li>Flammability: highly flammable gas</li><li>Flame: invisible, up to approx. 2,834 °C with oxygen</li><li>Properties: colorless, odorless, tasteless</li></ul><h4>Applications</h4><ul><li>Oxy-fuel welding of noble and non-ferrous metals</li><li>Quartz and glass processing</li><li>Reducing agent in chemistry and metallurgy</li><li>Generator cooling</li><li>Gas chromatography (carrier gas)</li><li>Flame ionization detectors (FID)</li><li>Food industry applications</li><li>Alternative fuel</li></ul>

Linde Hydrogen 5.0 – Gas Cylinder

Linde hydrogen 5.0 (≥99.999%) for GC and high-end applications. Maximum purity and stable performance for analytical and industrial use.

Hydrogen 5.0 from Linde is an ultra-high purity gas (≥ 99.999%) designed for the most demanding analytical and laboratory applications, as well as selected industrial processes. Its extremely low impurity levels make it ideal for gas chromatography and other techniques sensitive to gas quality.Hydrogen offers outstanding thermophysical properties, ensuring efficient heat transfer and high combustion efficiency. It burns with an invisible flame and produces no carbon or soot, enabling clean, contamination-free processes.Due to its exceptional purity, hydrogen 5.0 is the preferred choice for laboratory analysis, calibration, and applications requiring maximum reproducibility. It is supplied in pressurized cylinders for safe and flexible use.<h4>Key Features</h4><ul><li>Ultra-high purity ≥ 99.999%</li><li>Minimal impurities for analytical applications</li><li>Excellent thermophysical properties</li><li>Clean combustion without carbon or soot</li><li>Colorless, odorless, and tasteless</li><li>Ideal for GC, FID, and sensitive analytical workflows</li></ul><h4>Technical Specifications</h4><ul><li>Gas: Hydrogen (H₂)</li><li>Purity: ≥ 99.999% (5.0)</li><li>Supply form: pressurized steel cylinder</li><li>Flammability: highly flammable gas</li><li>Flame: invisible, up to approx. 2,834 °C with oxygen</li><li>Properties: colorless, odorless, tasteless</li></ul><h4>Applications</h4><ul><li>Gas chromatography (carrier gas)</li><li>Flame ionization detectors (FID)</li><li>Analytical instruments and calibration</li><li>Oxy-fuel welding and metal processing</li><li>Quartz glass processing</li><li>Chemical and metallurgical applications (reducing agent)</li><li>Reactor cooling</li><li>Glass fiber production</li><li>Meteorology (balloon gas)</li><li>Alternative fuel</li></ul>

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