This leaflet is intended as a comprehensive checklist outlining the key steps to consider when participating in a proficiency testing (PT) scheme. Selection of an appropriate PT scheme must be ensured [1]. It provides essential tips to help participants avoid common mistakes and achieve successful outcomes. The main stages of PT participation are covered, from receipt of PT items through to the review of received evaluations [1-3]. Documentation of outcomes for many of the topics addressed below is recommended, particularly for accreditation purposes.&nbsp;<h4>1. Prior to PT participation&nbsp;</h4><ul><li>Verify that the PT provider has up-to-date billing, shipping and technical contact information for the laboratory.&nbsp;</li><li>Ensure that the laboratory has documented procedures in place or, if necessary, prepare procedures for: reviewing PT results upon receipt; taking corrective actions when assessments indicate poor performance; conducting periodic reviews of PT results over time; storing PT reports.&nbsp;</li></ul><h4>2. Receipt of PT items&nbsp;</h4><ul><li>Open the package of PT items immediately upon receipt to check their condition. Contact the PT provider and request a replacement if any PT items are missing, broken, leaking or otherwise compromised.&nbsp;</li><li>Study the PT provider’s instructions carefully to ensure they are clear and understandable (e.g. handling, storage, pre-treatment, preparation, reporting of results).&nbsp;</li><li>Register, identify, and mark the PT items according to normal procedures in the laboratory.&nbsp;</li><li>Store the PT items in accordance with any instructions provided.&nbsp;</li></ul><h4>3. Measurements&nbsp;</h4><ul><li>Read the instructions supplied by the PT provider carefully before starting the measurements.&nbsp;</li><li>Carry out the measurements under conditions as close as possible to routine testing, unless otherwise instructed by the PT provider.&nbsp;</li><li>Ensure that the analysis is carried out to meet any measurement deadline requirements.</li></ul><h4>4. Reporting results&nbsp;</h4><ul><li>Allow sufficient time for reporting the results to the PT provider.&nbsp;</li><li>Report all the information required by the PT provider.&nbsp;</li><li>Ensure that the results are reported in the requested format (e.g. units, number of significant figures, decimal places).&nbsp;</li><li>Ensure that the results you are going to submit are those that you intend, correcting for any identified transcription errors (e.g. mix-up of samples or analytes).&nbsp;</li><li>Confirm that the submission process of the results to the PT provider has been completed.&nbsp;</li></ul><h4>5. Reviewing PT reports&nbsp;</h4><ul><li>Read the PT report as soon as possible and check that your results and other information are correctly represented; report any errors immediately to the PT provider.&nbsp;</li><li>Take notice of any comments on the specific PT round, evaluation of performance, and other matters relevant to the results of the PT round which provide valuable context to your individual results.&nbsp;</li><li>Review your assessed performance carefully in accordance with your laboratory procedures.&nbsp;</li><li>Store the PT report according to internal procedures.&nbsp;</li></ul><h4>6. Follow-up on participation in a PT scheme&nbsp;</h4><ul><li>Investigate any poor performance in accordance with your laboratory quality system [4].&nbsp;</li><li>Evaluate the impact of poor performance (e.g. risk that poor quality data may have been reported to customers).&nbsp;</li><li>Implement any corrective actions as relevant, and if possible, make use of any surplus PT items [5] to assess effectiveness.&nbsp;</li><li>Monitor any trends in performance over time, concentration levels, etc.&nbsp;</li></ul><blockquote>Information about PT providers and PT schemes can be obtained from your national accreditation body, from the <a target="_blank" rel="noopener noreferrer" href="https://www.eptis.org/">EPTIS website</a> or from other national or international organizations.</blockquote>

Basic instructions for participants in a proficiency testing scheme

Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 9th March 2026? Check out new documents from the field of spectroscopy/spectrometry and related techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">LabRulezGCMS</a> libraries.</blockquote>This week we bring you application notes by Agilent Technologies, Metrohm, Shimadzu and Thermo Fisher Scientific!<h3>1. Agilent Technologies: Spectral Transmission Measurements of Pharmaceutical Packaging</h3>Using the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=Cary+60+UV%E2%80%91Vis">Agilent Cary 60 UV‑Vis</a> Diffuse Reflectance Accessory following EP &lt;3.2.1&gt;, USP &lt;660&gt;, and USP &lt;661.2&gt;<ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_pharmaceutical_packaging_transmission_cary_60_uv_vis_dra_5994_8889en_agilent_2c933e5576.pdf">Full PDF for download</a></li></ul>Pharmaceutical containers play a significant role in maintaining final drug stability, integrity, and safety, from manufacturing to distribution to the end user. The ability of the packaging system to protect the drug from external agents is critical for quality assurance. Therefore, all pharmaceutical packaging systems must conform to stringent standards.&nbsp;Plastic and glass are commonly used materials for packaging, and they are typically transparent or opaque. Transparency to ultraviolet (UV) light can pose a risk to light‑sensitive pharmaceuticals, as exposure can initiate adverse—and sometimes harmful—photochemical reactions that can significantly affect drug quality and reduce shelf-life.1&nbsp;The EP and USP define well-established standards, designed to measure physiochemical and functional properties of packaging components intended to contain a drug product (pharmaceutical containers), to meet regulatory requirements. The EP Chapter &lt;3.2.1&gt; Glass Containers for Pharmaceutical Use includes a functionality test method to demonstrate adequate light resistance of colored glass containers through spectral transmission measurement. An included acceptance criterion specifies the allowed maximum amount of light transmitted by the tested material, defined by the drug product dosage administration form. For example, for glass containers that package oral drug products, the acceptance criterion defines that the observed spectral transmission should not exceed 10% at any wavelength in the range of 290 to 450 nm (&lt; 10%T).2 The identical test and criterion are found in USP Chapter &lt;660&gt; Containers – Glass.3 In addition, the USP Chapter &lt;661.2&gt; Plastic Packaging Systems for Pharmaceutical Use also includes the analogous functionality test method and acceptance criterion for plastic pharmaceutical packaging.4&nbsp;The <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=Cary+60+UV%E2%80%91Vis">Cary 60 UV-Vis spectrophotometer</a>, equipped with the Cary 60 UV-Vis DRA, was chosen for measurement due to its extended ability to reliably measure precise transmission of scattering materials (Figure 1). The Cary 60 UV-Vis is a versatile spectrophotometer; however, measuring materials like plastics and glass, which are textured, translucent, or opaque in a manner that scatters light can result in challenges in satisfactorily measuring light transmittance with standard techniques. In a standard spectrophotometer, scattering materials tend to diffuse transmitted light, deviating an unquantifiable amount of light from the direct optical path of the detector. The detector may not collect all the scattered (lost) light, resulting in inaccurate measurements and results.&nbsp;For this reason, the Cary 60 UV-Vis was equipped with an internal DRA, which uses a 50 mm integrating PTFE-coated sphere that easily sits inside the spectrophotometer's sample compartment. For these applications, using a DRA can optimize light collection. The sphere's design captures all scattered light uniformly, overcoming scattering losses for accurate measurement of transmitted light. In applications where total transmission is crucial for quality assurance, the DRA is an essential tool for accurate measurements.<h4>Conclusion&nbsp;</h4>In this application note, an Agilent Cary 60 UV-Vis spectrophotometer, fitted with an Agilent Cary 60 UV‑Vis DRA, was used to reliably and quickly determine the spectral transmission of packaging systems used for pharmaceuticals, following the EP &lt;3.2.1&gt;, USP &lt;660&gt;, and USP &lt;661.2&gt; test methods for functionality of light-resistant packaging systems. The integrating sphere enabled the instrument to accurately measure total transmittance of plastic and glass (scattering) materials.&nbsp;All containers presented less than the defined maximum %T specification, demonstrating light-resistance functionality for containing light-sensitive drug products for oral administration. This method illustrates the importance of accurate testing for quality assurance of pharmaceutical packaging. The Agilent Cary 60 UV-Vis spectrophotometer, paired with Cary WinUV Pharma software, delivers secure data management and compliance for regulated pharmaceutical labs.<h3>2. Metrohm: Multiparameter hops analysis by near-infrared spectroscopy (NIRS)</h3>Rapid determination of alpha acids, beta acids, cohumulone content, total oil content, HSI, and moisture<ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_nir_130_download_6177b89ee1.pdf">Full PDF for download</a></li></ul>The quality of hops and hop pellets is vital across the entire brewing supply chain. Traditional methods used for quality control (e.g., titration and HPLC) are highly accurate and widely accepted. They are also time consuming, labor intensive, and dependent on chemical reagents which not only incur ongoing material costs but also require careful handling and proper disposal. Near-infrared spectroscopy (NIRS) offers a compelling alternative when ultra-high precision is not necessary. It enables the rapid analysis of multiple parameters within a minute without using any chemicals. This Application Note outlines the measurement setup and the results of cohumulone, hop oils, and moisture content, the hop storage index (HSI), and hops acids analysis with NIRS.<h4>EXPERIMENTAL EQUIPMENT&nbsp;</h4>More than 500 fresh hop samples and ground hop pellets were analyzed on an <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=220&amp;search=omnis+nir">OMNIS NIR Analyzer Solid</a> (Figure 1). The samples were added to an OMNIS sample cup and analyzed in diffuse reflection mode. To include sample variety, the sample rotated during measurement to collect spectra from different locations. The automatically averaged spectra were used for model development. Spectra acquisition, model development, and validation were carried out with the OMNIS Software.&nbsp;Reference values for alpha acids were obtained using various official methods, including EBC 7.4, EBC 7.5, and EBC 7.7. Total oils and beta acid content were determined using EBC 7.4, while EBC 7.7 was employed for cohumulone analysis. Moisture content and the hop storage index (HSI) were measured using a halogen moisture analyzer and a UV-VIS photometer, respectively.<h4>CONCLUSION</h4>This Application Note demonstrates the feasibility of using NIR spectroscopy for the analysis of freshly harvested hops and ground hop pellets to determine cohumulone, moisture, and total oil content, HSI, and alpha and beta acids. Using alpha acids as an example, the difference between a prediction model covering the full concentration range and a model specific to a narrower range was highlighted. The latter reduced the prediction error by a factor of two.&nbsp;Users can apply this approach to maximize accuracy. In the OMNIS Software, both models can be combined to automatically perform the following sequence. First, the alpha acid concentration is estimated using the broad-range model; then, a more precise prediction is made using the restricted-range model.<h3>3. Shimadzu: Observation of Acrylic Block Fracture during Impact Compression Using the Hopkinson Bar Method</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_01146_en_dc42e77a9c.pdf">Full PDF for download</a></li></ul><h4>User Benefits</h4><ul><li>The HPV -X3 offers three times the resolution of conventional models, enabling observation of specimen fracture at much higher resolution.</li><li>With a maximum frame rate of 20 Mfps, the HPV-X3 is well-suited for observing high-speed phenomena such as an impact test</li></ul>Understanding materials properties is critical to product design. In particular, for applications such as transportation equipment, where materials may be subjected to impact loads, it is essential to evaluate not only static properties but also impact properties. When subjected to impact, materials may exhibit stress and strain characteristics different from those under static loading, making it essential to quantify these characteristics through impact testing.&nbsp;The Hopkinson bar method is a well-established technique for impact compression testing. Proposed by B. Hopkinson, this method enables detailed analysis of a material’s impact response and evaluation of its fracture properties by subjecting the specimen to a sudden force using a bar-launching device. This paper presents an example of an impact compression test on an acrylic specimen with a central circular hole, recorded with an HPV-X3 high-speed video camera (Fig. 2) using the Hopkinson bar method.<h4>Imaging System&nbsp;</h4>The imaging devices are listed in Table 1, and the imaging conditions are listed in Table 2. As shown in Fig. 4(b), laser illumination was directed from the rear of the specimen toward the lens, and imaging was performed with the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=1&amp;search=HPV-X3">HPV-X3</a> using a close-up ring, bellows, and macro lens. This setup enabled observation of the fracture process in the acrylic block. Two types of imaging were conducted: observation of crack propagation immediately after loading, and observation of subsequent fracture.<h4>Conclusion&nbsp;</h4>The impact compression test of an acrylic specimen using the Hopkinson bar method was observed using the HPV-X3 highspeed video camera. Inside the compressed specimen, the propagation of a wavefront believed to be a stress wave was first observed. Subsequently, cracks propagated from the central circular hole toward the left and right surfaces, and finally, diagonal cracks formed, leading to complete fracture. The progress of this series of fracture processes was clearly captured.&nbsp;The HPV-X3 has three times the resolution of the previous <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=1&amp;search=HPV-X2">HPVX2 model</a>, enabling more detailed observation of specimens during impact tests, including the Hopkinson bar method. Furthermore, because fracture phenomena during impact testing occur at high speeds, the HPV-X3, which can record images at up to 20 Mfps, is ideal for capturing them.<h3>4. Thermo Fisher Scientific: Analysis of silica in air filters using ARL X’TRA Companion X-ray Diffractometer</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/analysis_of_silica_in_air_an41521_a3b8eb33d5.pdf">Full PDF for download</a></li></ul>The analysis of silica in air filters is a critical aspect of occupational health and safety, aimed at protecting workers from the harmful effects of inhaling crystalline silica particles, which can lead to diseases such as silicosis and lung cancer. The NIOSH 7500 method (NIOSH, 2003) provides a detailed and standardized procedure for the determination of crystalline silica in air samples using X-ray diffraction (XRD). This method involves the collection of air samples on filters, which are then analyzed to identify and quantify the crystalline silica phases, including quartz, cristobalite, and tridymite.&nbsp;XRD is chosen for its high specificity and sensitivity in distinguishing different crystalline forms of silica, making it a reliable analytical technique. The method outlined in NIOSH 7500 requires meticulous sample preparation, including the proper collection and handling of air filters, calibration with known standards, and strict adherence to analytical parameters to ensure accurate and reproducible results. Following the NIOSH 7500 norm and equivalent standards helps ensure the reliable monitoring of workplace air quality, thereby safeguarding workers’ health. The use of XRD in analyzing silica in air filters is an essential component of industrial hygiene and environmental monitoring programs, facilitating the detection and control of hazardous silica exposure in occupational settings.<h4>Instrument and software&nbsp;</h4>The <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2296">Thermo Scientific™ ARL™ X’TRA Companion X-ray Diffractometer</a> (c.f. Figure 1) is a simple, easy-to-use benchtop XRD instrument for routine phase analysis as well as more advanced applications. The ARL X’TRA Companion XRD uses a θ/θ goniometer (160 mm radius) in Bragg-Brentano geometry coupled with a 600 W X-ray source (Cu or Co). The radial and axial collimation of the beam is controlled by divergence and Soller slits, while air scattering is reduced by a variable beam knife. An integrated water chiller is available on demand. Thanks to the innovative solid state pixel detector (55 x 55 μm pitch), the ARL X’TRA Companion XRD provides very fast data collection and comes with one-click Rietveld quantification capabilities and automated result transmission to a LIMS (laboratory information management system).<h4>Your benefits&nbsp;</h4>The ARL X’TRA Companion XRD provides data perfectly suited to quantify respirable quartz in air filters. Utilizing a calibration curve in a one-click refinement delivers results within minutes, ensuring ease-of-use for operators and reducing training requirements. XRD analysis of air filter samples complies with the NIOSH 7500 standard.

News from LabRulezICPMS Library - Week 11, 2026

How can we make the production of supercapacitors for energy storage more sustainable and replace the traditionally used but toxic solvent NMP (N-methyl-2-pyrrolidone)? According to scientists from CATRIN at Palacký University, the “green” solvents Cyrene and Tamisolve may be a suitable alternative. In an article published in the <a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1385894725130696?via%3Dihub#s0060">Chemical Engineering Journal</a>, they have shown that these solvents can be used in production without reducing the performance of the equipment. They thus offer a path to the next generation of sustainable, high-performance supercapacitors for industrial use.“Supercapacitors are one of the modern technologies for storing electric energy. As sustainable energy storage becomes more prominent, it is essential to replace the hazardous solvents used in the production of supercapacitor electrodes. Our study presents Cyrene and Tamisolve as environmentally friendly alternatives to the toxic solvent NMP, which is traditionally used in production. Both tested solvents enabled the preparation of electrodes that maintain high electrochemical performance while improving environmental compatibility,” said Michal Otyepka, corresponding author of the article.The electrodes were prepared using nitrogen-doped graphene as the active material in combination with two types of binders. The first was a common fluorinated binder (PVDF), which is widely used in industry, including in the manufacturing of battery electrodes. The researchers also tested a fluorine-free binder (PVP), which has a lower environmental impact and is more soluble in environmentally friendly solvents. Using various combinations, they monitored the performance and stability of the electrodes as well as their mechanical resistance.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CATRIN_Vedci_z_CATRIN_nabizeji_zelenejsi_cestu_pro_vyrobu_superkondenzatoru_443775296a.jpg" alt="CATRIN: CATRIN researchers offer a “greener” way to make supercapacitors" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CATRIN_Vedci_z_CATRIN_nabizeji_zelenejsi_cestu_pro_vyrobu_superkondenzatoru_443775296a.jpg 245w," sizes="100vw" width="1536" height="768">“The results showed that not only can the alternative solvents Cyrene and Tamisolve fully replace the toxic solvent NMP, but also that the prepared electrodes have the necessary mechanical properties. Their compatibility with both fluorinated PVDF and non-fluorinated PVP binders, together with excellent layer uniformity and electrochemical stability, makes them ideal for use in scalable applications. This is essential for industrial production,” said the publication’s first author, Ivan Dědek.Cyrene, or dihydrolevoglucosenone, is obtained from renewable biomass sources such as cellulose. Tamisolve (N-butyl-2-pyrrolidone) is a substance related to the commonly used NMP, but is more gentle on human health and the environment.Supercapacitor research has been a priority at CATRIN for almost ten years. In addition to developing new active materials, such as the successful nitrogen-doped graphene (SC-GN3), it also focuses on environmentally friendly and industrially feasible manufacturing processes. The replacement of toxic NMP with the “greener” solvents Cyrene and Tamisolve confirms that more sustainable production can go hand in hand with high performance and represents an important step towards industrial implementation.<blockquote><h4>The original article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1385894725130696?via%3Dihub#s0060">Toward transitioning to green and sustainable supercapacitors</a></h4>Ivan Dědek, Vojtěch Kupka, Veronika Šedajová, Petr Jakubec, Matěj Navrátil, Michal Otyepka&nbsp;Chemical Engineering Journal, 529, 2026, 172220<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1016/j.cej.2025.172220">https://doi.org/10.1016/j.cej.2025.172220</a><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote><h4>Abstract</h4>The rapid advancement of supercapacitor technologies has intensified the demand for sustainable electrode fabrication methods that minimize environmental impact. A major challenge arises from the extensive use of the toxic solvent N-methyl-2-pyrrolidone (NMP), which is subject to increasingly stringent regulatory restrictions. We demonstrate that NMP can be effectively replaced with two green solvents, dihydrolevoglucosenone (Cyrene) and N-butyl-2-pyrrolidone (Tamisolve), without compromising electrochemical performance. Electrode formulations were prepared using nitrogen-doped graphene as the active material, in combination with either polyvinylidene fluoride (PVDF), a widely employed fluorinated binder, or polyvinylpyrrolidone (PVP), a non-fluorinated alternative with improved environmental profile. Optimized coatings exhibited high mass loadings exceeding 6 mg cm−2 while maintaining strong adhesion to current collectors, an often overlooked yet critical parameter for scalable manufacturing. Electrochemical testing revealed that PVDF in Cyrene delivered an energy density of 66.6 Wh kg−1 at a power density of 1.85 kW kg−1, with excellent cycling stability, retaining 91 % of capacitance after 100,000 cycles. PVP in Cyrene provided a more environmentally benign alternative, achieving an energy density of 64.2 Wh kg−1 at 1.80 kW kg−1, with 78 % capacitance retention after 100,000 cycles, thereby highlighting the trade-off between performance and sustainability.

CATRIN researchers offer a “greener” way to make supercapacitors

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Application

Scientific article

Science and research

Eurachem is a European network promoting international traceability of chemical measurements and good analytical practice. It provides expert guidance, supports method validation, uncertainty evaluation, proficiency testing, and facilitates discussion on technical and policy issues in analytical quality.

Eurachem

The Czech Advanced Technology and Research Institute (CATRIN) at Palacký University is a cutting-edge scientific hub dedicated to advancing research in the fields of nanotechnology, biotechnology, and biomedicine. At its core, CATRIN boasts outstanding scientific teams, featuring international researchers. We emphasize interdisciplinarity, foster global collaborations, and work to translate our research findings into practical applications.

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Thermo Scientific Element 2 HR-ICP-MS

Perform accurate and reliable quantitative multi-element analyses at trace level, with the highest sensitivity and without complicated sample preparation with the Thermo Scientific™ Element™ 2 HR-ICP-MS.

Clean up your spectra. Make your analysis easy. High-Resolution ICP-MS is made for the most flexible and reliable analyses, for the best analytical results. Perform accurate and reliable quantitative multi-element analyses at trace level, with the highest sensitivity and without complicated sample preparation. The Thermo Scientific™ Element™ 2 and Element XR™ High Resolution ICP-MS systems cover the mg/L to sub pg/L concentration range—making them especially suitable for semiconductor, geological and material science laboratories.The Element 2 and Element XR High-Resolution ICP-MS provide class-leading elimination of interferences for the highest level of confidence. With ultra-sensitive and reliable multi-element analyses at trace-level concentrations, there’s no need for complicated sample preparation and method development.In mass spectrometry, spectral interferences occur when the mass-to-charge ratio (m/z) of interfering ions overlap with analyte ions. These interferences are the primary limitation of ICP-MS. Fortunately, there’s a better way. The high mass resolution potential of a sector-field mass spectrometer can physically distinguish and separate an analyte from interferences by exploiting small differences in mass-to-charge. Therefore, high resolution (HR) ICP-MS can quantify concentrations and determine precise isotope ratios for elements across nearly the entire periodic table, regardless of the sample matrix.<figure class="image"><img style="aspect-ratio:779/639;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Element_2_HR_ICP_MS_3960103a20.jpg" alt="Thermo Scientific™ Element™ 2 HR-ICP-MS: High mass resolution (R = 10,000) takes advantage of slight mass differences to analyze elements in the most challenging sample matrices. As an example, Arsenic (75As) in a chlorine matrix is masked by argon chloride (40Ar35Cl, 38Ar37Cl) without using high resolution." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Element_2_HR_ICP_MS_3960103a20.jpg 190w," sizes="100vw" width="779" height="639"></figure>High mass resolution (R = 10,000) takes advantage of slight mass differences to analyze elements in the most challenging sample matrices. Arsenic (75As) in a chlorine matrix is masked by argon chloride (40Ar35Cl, 38Ar37Cl) without using high resolution. Selenium (Se) is another key element that benefits from high resolution in common matrices. Beyond chloride matrices, high resolution is frequently applied to separate oxide, argide and nitride interferents, as well as multiply charged ions.<ul><li>Low resolution analyzes non-interfered isotopes with the highest sensitivity.</li><li>Medium resolution guarantees interference-free analysis for most elements in the majority of matrix types.</li><li>High resolution provides unequivocal separation of analytes and interferences in the most challenging matrices</li></ul>The simplicity of high-resolution ICP-MS allows the most advanced performance, without compromising on straightforward and reliable method development. This makes the Element series the platform of choice in top-level research and metrology institutions, as well as advanced routine analysis laboratories across the globe.<h3>Features and benefits</h3><ul><li>High mass resolution: Accurately measure isotope signals separate from spectral interferences and produce clean elemental spectra while retaining flexibility.</li><li>Straightforward analytical methods: Providing visual confirmation of accurate measurements.</li><li>Interference removal: no use of reactive gases.</li><li>High sensitivity: Get accurate and precise multi-element analysis down to pg·L-1 concentrations for all resolutions. The Element XR HR-ICP-MS increases the linear dynamic range by an additional three orders of magnitude for maximum flexibility.</li><li>Ideal for transient multi-elemental signals, such as laser ablation, HPLC, GC, CE, FFF.</li><li>High-precision isotope ratios.</li><li>An advanced research tool with the reliability and robustness to serve in 24/7 production control.</li></ul><figure class="image"><img style="aspect-ratio:650/542;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Element_2_HR_ICP_MS_2_b2de21a704.jpg" alt="Thermo Scientific™ Element™ 2 HR-ICP-MS" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Element_2_HR_ICP_MS_2_b2de21a704.jpg 187w," sizes="100vw" width="650" height="542"></figure><h3>Element 2 HR-ICP-MS</h3>The workhorse for semiconductor applications.The high performance, double-focusing magnetic sector field Element 2 HR-ICP-MS is optimized for ease-of-use, stability and productivity. Get access to a powerful technique for solving specific problems with excellent sensitivity and signal-to-noise ratio.

Thermo Scientific Element XR HR-ICP-MS

Clean up your spectra. Make your analysis easy. High-Resolution ICP-MS is made for the most flexible and reliable analyses, for the best analytical results. Perform accurate and reliable quantitative multi-element analyses at trace level, with the highest sensitivity and without complicated sample preparation. The Thermo Scientific™ Element™ 2 and Element XR™ High Resolution ICP-MS systems cover the mg/L to sub pg/L concentration range—making them especially suitable for semiconductor, geological and material science laboratories.The Element 2 and Element XR High-Resolution ICP-MS provide class-leading elimination of interferences for the highest level of confidence. With ultra-sensitive and reliable multi-element analyses at trace-level concentrations, there’s no need for complicated sample preparation and method development.In mass spectrometry, spectral interferences occur when the mass-to-charge ratio (m/z) of interfering ions overlap with analyte ions. These interferences are the primary limitation of ICP-MS. Fortunately, there’s a better way. The high mass resolution potential of a sector-field mass spectrometer can physically distinguish and separate an analyte from interferences by exploiting small differences in mass-to-charge. Therefore, high resolution (HR) ICP-MS can quantify concentrations and determine precise isotope ratios for elements across nearly the entire periodic table, regardless of the sample matrix.<figure class="image"><img style="aspect-ratio:779/639;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Element_2_HR_ICP_MS_3960103a20.jpg" alt="Thermo Scientific™ Element XR™ HR-ICP-MS: High mass resolution (R = 10,000) takes advantage of slight mass differences to analyze elements in the most challenging sample matrices. As an example, Arsenic (75As) in a chlorine matrix is masked by argon chloride (40Ar35Cl, 38Ar37Cl) without using high resolution." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Element_2_HR_ICP_MS_3960103a20.jpg 190w," sizes="100vw" width="779" height="639"></figure>High mass resolution (R = 10,000) takes advantage of slight mass differences to analyze elements in the most challenging sample matrices. Arsenic (75As) in a chlorine matrix is masked by argon chloride (40Ar35Cl, 38Ar37Cl) without using high resolution. Selenium (Se) is another key element that benefits from high resolution in common matrices. Beyond chloride matrices, high resolution is frequently applied to separate oxide, argide and nitride interferents, as well as multiply charged ions.<ul><li>Low resolution analyzes non-interfered isotopes with the highest sensitivity.</li><li>Medium resolution guarantees interference-free analysis for most elements in the majority of matrix types.</li><li>High resolution provides unequivocal separation of analytes and interferences in the most challenging matrices</li></ul>The simplicity of high-resolution ICP-MS allows the most advanced performance, without compromising on straightforward and reliable method development. This makes the Element series the platform of choice in top-level research and metrology institutions, as well as advanced routine analysis laboratories across the globe.<h3>Features and benefits</h3><ul><li>High mass resolution: Accurately measure isotope signals separate from spectral interferences and produce clean elemental spectra while retaining flexibility.</li><li>Straightforward analytical methods: Providing visual confirmation of accurate measurements.</li><li>Interference removal: no use of reactive gases.</li><li>High sensitivity: Get accurate and precise multi-element analysis down to pg·L-1 concentrations for all resolutions. The Element XR HR-ICP-MS increases the linear dynamic range by an additional three orders of magnitude for maximum flexibility.</li><li>Ideal for transient multi-elemental signals, such as laser ablation, HPLC, GC, CE, FFF.</li><li>High-precision isotope ratios.</li><li>An advanced research tool with the reliability and robustness to serve in 24/7 production control.</li></ul><figure class="image"><img style="aspect-ratio:650/542;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Element_2_HR_ICP_MS_2_b2de21a704.jpg" alt="Thermo Scientific™ Element™ 2 HR-ICP-MS" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Element_2_HR_ICP_MS_2_b2de21a704.jpg 187w," sizes="100vw" width="650" height="542"></figure><h3>Element XR HR-ICP-MS</h3>The gold standard for full elemental screening in high dynamic range laser ablation and solution work, and for large isotope ratios applications.The combination of a dual-mode SEM with a Faraday detector increases the linear dynamic range by an additional three orders of magnitude. This enables analysis of any matrix element straight without further dilution or precautions to avoid detector damage from inadvertently measuring high level elements.

Thermo Scientific Neoma MS/MS MC-ICP-MS

The Neoma MS/MS MC-ICP-MS is the first dedicated collision/reaction cell MC-ICP-MS with unique pre-cell mass filtering technology, allowing you to separate out isobaric interferences.

<div><div id="product-description">Separate out isobaric interferences to achieve new levels of precision and accuracy in your isotope research. There are some situations when even the highest resolution is not enough and isobaric interferences cannot be resolved, even with the best ICP-MS instruments available. Thermo Scientific™ Neoma™ MS/MS MC-ICP-MS provides the solution.The Neoma MS/MS MC-ICP-MS is the first dedicated collision/reaction cell MC-ICP-MS with unique pre-cell mass filtering technology, allowing you to separate out isobaric interferences and opening up new avenues in the field of laser ablation MC-ICP-MS and beyond.</div><div><h3>Modes</h3><ul><li>Full transmission mode: High-precision isotope analysis without utilizing the collision/reaction cell technology. Additionally, the pre-cell mass filter can be used to remove matrix elements, boosting sensitivity and improving abundance sensitivity.</li><li>Collision/reaction cell mode: For isotope systems with significant isobaric interferences, patented pre-cell mass filter technology removes matrix elements that might act to cause secondary reactions in the CRC.</li></ul><figure class="image"><img style="aspect-ratio:650/468;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Neoma_MS_MS_MC_ICP_MS_0986e1671d.jpg" alt="Thermo Scientific™ Neoma™ MS/MS MC-ICP-MS." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Neoma_MS_MS_MC_ICP_MS_0986e1671d.jpg 217w," sizes="100vw" width="650" height="468"></figure><h3>Applications</h3><ul><li>In-situ Rb-Sr dating: Unprecedented precision for dating geological samples by a combination of the pre-cell mass filter, the collision/reaction cell and the multicollector detector array.</li><li>Interference-free Ti isotope analysis: The pre-cell mass filter can be used to remove molecular and doubly charged interferences, and the collision/reaction cell can be used to remove isobaric interferences.</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_001006_sr_ioms_b_isotopes_an001006_en_90167475a4.pdf">In-situ boron isotope analysis of biogenic carbonates</a>: Unprecedented accuracy LA-MC-ICP-MS analysis by using the pre-cell mass filter to remove interferences from scattered Ca4+ ions on 10B</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_001035_ioms_mc_icp_ms_neoma_potassium_an001035_em_en_913d82d28d.pdf">K isotope analysis</a>: Interference of 40Ar+ can hamper the precision and accuracy of the K isotope analysis. Remove the 40Ar+ interference with either: (1) the <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/order/catalog/product/BRE0014262">eXtra High Resolution (XHR)</a> of Neoma MC-ICP-MS, or (2) for smaller sample sizes, the use of H2 and He in the collision/reaction cell to neutralize 40Ar and 40ArH</li></ul><h3>Technology options</h3><ul><li>Extended choice with 24 amplifier array: Ion current amplifiers are mounted in a doubly shielded, evacuated and thermostatted housing with a temperature stability of 0.01°C/hour, to guarantee baseline and gain stability.</li><li>Enhanced variable detector array: Precise alignment of all 11 cups with ion beams of different dispersions to ensure the flexibility to cover isotopic applications from Li through to U, in low or high resolution, and without compromising the native dispersion of the mass analyzer.</li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/order/catalog/product/BRE0025160">Jet Interface</a>: The Jet Interface, in combination with a desolvating nebulizer system, increases sensitivity by 10 to 20 times compared to standard wet plasma.</li><li>Choice of resolution: 3 different mass resolutions for maximizing the sensitivity of your analysis whilst allowing interferences to be resolved.</li><li>Flexibility of detector types: A flexible, three-detector system spanning &gt;9 orders of magnitude in signal intensity range (1 cps – 6 Gcps). The central channel is equipped with a dual-mode detector that can be switched from Faraday cup to SEM ion counter, and with the proprietary relay matrix, any amplifier can be assigned to any of the Faraday cups via software.</li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/order/catalog/product/IQLAAMGAATFAPTMZZZ">1013Ω amplifier technology</a>: Ensures fast response times with extremely low noise characteristics. The benefits of Faraday cups can be realized at low signal intensities (30 kcps – 3 Mcps), delivering external precisions that approach the ultimate limits of counting statistics.</li></ul></div></div>

Thermo Scientific Neoma multicollector ICP-MS (MC-ICP-MS)

Perform routine isotope analysis or explore novel isotopes in unknown materials using the Thermo Scientific Neoma multicollector ICP-MS (MC-ICP-MS).

<div><div id="product-description">Perform routine isotope analysis or explore novel isotopes in unknown materials using the Thermo Scientific Neoma multicollector ICP-MS (MC-ICP-MS). This ICP-MS system builds on our multicollector technology to deliver all the advantages of high-precision isotope ratio analysis, with none of the limitations. It includes state-of-the art software and hardware, features flexible and sensitive detector technology, a sensitive ion source and excellent mass resolving power, enabling challenging isotope analyses.Now Neoma MC-ICP-MS comes with the upgrade pathway to <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1675">Thermo Scientific™ Neoma™ MS/MS MC-ICP-MS</a>, the first dedicated collision/reaction cell MC-ICP-MS with unique pre-cell mass filtering technology. Allowing you to separate out isobaric interferences and opening up new avenues in the field of laser ablation MC-ICP-MS and beyond.</div><div><h3>Technology that transforms your science</h3>Building on the strength of our multicollector technology, the Neoma MC-ICP-MS system blends the cutting-edge and field-proven technologies found in Thermo Scientific high-resolution isotope ratio mass spectrometers and <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products?category=232&amp;manufacturerItems=3&amp;search=iCAP%E2%84%A2+Qnova">Thermo Scientific™ iCAP™ Qnova ICP-MS systems</a>:<ul><li>Robust iCAP Qnova ICP-MS source</li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/order/catalog/product/BRE0025160">Jet interface</a>: for highest sensitivity and stability in wet and dry plasma</li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/order/catalog/product/BRE0014262">Extra High resolution (XHR)</a>: enabling hydride interference removal</li><li>Limit breaking detector array: 11 moveable collectors. No limitations</li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/order/catalog/product/IQLAAMGAATFAPTMZZZ">1013 Ω Amplifier Technology</a> with extended dynamic range</li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/order/catalog/product/BRE0024689">Retarding Potential Quadrupole (RPQ)</a>: for excellent abundance sensitivity enabling accurate quantification of extreme isotope ratios</li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/order/catalog/product/BRE0024305">Multi Ion Counting (MIC)</a> packages: dedicated for specific nuclear and geochronology applications.</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1489">Thermo Scientific™ Qtegra™ Intelligent Scientific Data Solution™ (ISDS) Software</a>: for ultimate ease of use and flexibility in instrument control and method design.</li></ul><figure class="image"><img style="aspect-ratio:650/403;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Neoma_multicollector_ICP_MS_MC_ICP_MS_2_a36be9f4b3.jpg" alt="Thermo Scientific™ Neoma™ multicollector ICP-MS (MC-ICP-MS)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Neoma_multicollector_ICP_MS_MC_ICP_MS_2_a36be9f4b3.jpg 245w," sizes="100vw" width="650" height="403"></figure><h3>High-precision isotope ratio analysis, simplified</h3><ul><li>Delivers performance with market-leading sensitivity, isotope ratio precision and accuracy</li><li>Features the latest hardware and software making the system easier to use than legacy MC-ICP-MS systems</li><li>Offers operator-focused <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1489">software</a>, with integrated first- and third-party peripheral control to streamline workflows and enhance productivity</li><li>Enables high throughput for routine applications while retaining the flexibility required for researching new applications</li></ul><h3>Break through the noise</h3>There are some situations when even the highest resolution is not enough. Isobaric interferences cannot be resolved even with the best ICP-MS instruments available. <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/order/catalog/product/IQLAAMGAATFARHMBNK">Thermo Scientific™ Neoma™ MS/MS MC-ICP-MS</a>&nbsp;provides the solution.For users familiar with triple quad ICP-MS technology, the Neoma MS/MS MC-ICP-MS represents the next leap forward in terms of precision and accuracy. With a similar structure of filter, react, separate, the Neoma MS/MS MC-ICP-MS allows for the effective removal of isobaric interferences without compromising sensitivity, with the additional benefit of simultaneous isotope analysis, for ultimate precision and accuracy of your isotope ratio.</div></div>

Products from category ICP/HRMS - page 1

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