News from LabRulezICPMS Library - Week 43, 2024

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Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in week 43, 2024? Check out new documents from the field of spectroscopy, especially ICP/MS techniques!
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This week we bring you applications and other documents by Agilent Technologies, Shimadzu, Anton Paar, and Thermo Fisher Scientific!
1. Thermo Fisher Scientific: Robust and reliable analysis of soil samples using single quadrupole ICP-MS
- Application
Goal
To highlight the use of the Thermo Scientific™ iCAP™ MSX ICP-MS for robust and accurate analysis of soil samples.
Introduction
Soil is an essential part of our ecosystem and plays an important role in the development and sustainability of the biosphere. Maintaining fertility and quality of soil is an ultimate prerequisite for ensuring human and animal health. Environmental pollution is an important cause for concern in modern society, and applicable regulations and standards focus on regularly testing soils and sediments from different areas. For similar reasons, sludges, which are often used as fertilizers, are also regularly tested to detect harmful elements and compounds that may degrade soil quality and eventually pose a threat to human health and safety. Researchers and applied testing laboratories work to fully understand the root cause and potential impact of soil pollution, as well as its distribution through mobilization or diffusion. Accurate and rapid analysis of the content of metal substances in soil is a key step in accomplishing this important task.
Inductively coupled plasma mass spectrometry (ICP-MS) is a technique that is widely used for the elemental analysis of complex samples such as soil and sludge digests. In this application note the new Thermo Scientific™ iCAP™ MSX ICP-MS was used for the analysis of soils, sludges, and sediments. Argon Gas Dilution (AGD) reduced the manual work involved in sample dilution, and at the same time, enhanced the overall matrix tolerance of the system to different environmental samples. This study demonstrates how AGD can be used to readily deliver repeatable and reliable results with high accuracy and sensitivity in laboratories tasked to analyze high sample loads.
Conclusions
The iCAP MSX ICP-MS is an excellent choice for laboratories performing soil and sediment digests with varying compositions. It provides the robustness and matrix tolerance needed to analyze the often challenging samples, yet at the same time provides the sensitivity required to detect important contaminants at relevant levels. The integrated argon gas dilution for controlled and automatic dilution of the sample aerosol effectively minimizes matrix effects without the need for laborious additional sample preparation. Robustness combined with accuracy and high sensitivity, enabling the analysis of several major as well as trace elements in soil samples with high reliability, makes this method an ideal option for seamless analysis of hundreds of soil samples daily. The most important results of this study are summarized below:
- The use of AGD Level 10 combined with KED mode measurements yielded excellent linearity, wide linear dynamic range, high sensitivity, and interference free data for a range of different elements in soil samples.
- Online sample dilution using integrated AGD offers an automatic solution for diluting soil sample digests to the desired extent and results in accurate and reliable analysis with minimal to no matrix induced signal variation.
- The accuracy of the method is confirmed by the SRM recoveries as well as the stable QC analyte response which were both found to be within 80–120% for the different analytes on repeated analysis over several hours.
- The internal standard recoveries remained stable and extremely consistent within 80–120% throughout the 8-hour robustness test, proving that a reliable uninterrupted and robust high-quality analysis of different types of soil samples can be easily carried out using the iCAP MSX ICP-MS
2. Agilent Technologies: Cosmetic Raw Material Identification Testing Through Transparent and Opaque Containers
- Application
Abstract
With the adoption of stricter requirements for the manufacturing of cosmetic products, the Good Manufacturing Practice landscape has evolved and impacted quality control (QC) processes to meet quality, costs, and efficiency requirements. In particular, raw material identification (ID) testing has seen the adoption of at‑the‑point‑of‑need solutions in the warehouse. The Agilent Vaya Raman is the latest generation Raman handheld spectrometers for raw material ID testing directly through containers. This application note discusses the capability of Vaya for cosmetics raw material ID testing through transparent and opaque containers and describes the impact on raw material receipt processes.
Conclusion
The Agilent Vaya Raman spectrometer has the capability to distinguish a unique Raman spectrum for each material in this study, enabling their direct ID verification while in quarantine. There is no need for sample or container preparation before scanning a the contents of a container using the ID verification feature of the Vaya. Users are simply asked to place the Vaya directly against the container and initiate the process. The instrument remains stationary during the spectrum acquisition phase. On average, the scanning time for through‑transparent is 10 to 15 seconds, and for opaque containers, 35 to 40 seconds. The Vaya Raman raw material identity verification system, with its rapid analysis times and capability to measure through both transparent and opaque containers, is perfectly adapted for handling large quantities of raw materials used in the formulation of cosmetic products. It enables immediate identification of raw materials in quarantine upon receipt. The Vaya Raman instrument simplifies the process by reducing or eliminating many steps required in FTIR or conventional Raman spectroscopy, such as cleaning instrumentation and the sampling booth or moving containers to and from the quarantine area for sampling and analysis. Using Vaya allows for future preparation of raw material receipts and can accommodate increased production volumes or new sampling requirements such as 100% ID, all with minimal investment.
3. Anton Paar: Efficiency Meets Compliance in Spectroscopy
- Brochures and Specifications
Quick identification and verification of substances with Cora 5001 and/or Lyza 7000 with Anton Paar’s Spectroscopy Suite.
Cora 5001 and/or Lyza 7000, in combination with Anton Paar’s Spectroscopy Suite software, is the solution tailored to incoming goods inspection and R&D in the regulated environment.
You need results, not spectra: The system takes all complicated spectroscopy aspects out of the daily measuring routines. Predefined workflows and settings speed up measurements and avoid errors before they can even occur.
All workflows, like running samples, setting up methods, and generating reference libraries, are specifically designed to adhere to stringent compliance regulations.
Your challenges:
- I operate in the regulated environment and can never compromise on lifetime data integrity
- I must always be able to demonstrate that the system adheres to 21 CFR Part 11 and EU GMP Annex 11
- I need a system that avoids errors in the first place instead of making me chase them afterwards on the basis of audit trail entries
- I need to check 100 % of the supplied goods, so no incorrect or contaminated raw materials are used in production, which could ruin the entire batch
- It’s my job to increase the efficiency of the QC laboratory, and I’m looking for a quick test to verify the chemical composition
Cora 5001 and/or Lyza 7000 with Anton Paar’s Spectroscopy Suite − the solution to your needs.
4. Shimadzu: Evaluating Chromotropism with a Spectrophotometer: Solvatochromism and Thermochromism
- Application
User Benefits
- Observe changes in absorbance while varying sample temperatures.
- The TCC-100, a thermoelectrically temperature-controlled cell holder controls sample temperatures in the range of 7 to 60 °C without the need for cooling water.
- The CPS-100, a six-cell thermoelectrically temperature-controlled cell positioner controls the temperatures of up to six samples concurrently.
Introduction
Reversible changes in optical properties due to external stimuli are referred to collectively as chromotropism. For example, the changing of a color from exposure to light is called photochromism, from heat is called thermochromism, and from a change in solvent polarity is called solvatochromism. These chromotropic phenomena have everyday applications, such as checking moisture absorption with silica gel and the printing of receipts. While UV-Vis spectrophotometers are used to measure these phenomena quantitatively, they require additional equipment depending on the type of external stimulus causing the color change. So while, solvatochromism can be measured without additional equipment, measuring thermochromism requires a device to heat the sample. (Application News 01-00016 describes using a UV-Vis spectrophotometer to measure thermochromism in a solid sample.) Measuring photochromism requires irradiating the sample with light, which can be performed using Shimadzu’s dedicated photoreaction evaluation system called Lightway. More detailed information about Lightway can be found in Application News No. A625. This Application News describes an evaluation of the solvatochromism and thermochromism of a metal complex solution. To measure the thermochromism, a thermoelectrically temperature-controlled cell holder (TCC-100) and a six-cell thermoelectrically temperature-controlled cell positioner (CPS-100) were used. 1
Conclusion
This Application News evaluated the solvatochromism and thermochromism of solutions of cobalt chloride. The changing of colors due to solvatochromism was evaluated quantitatively using the optional color calculation software for LabSolutions UV-Vis. The TCC-100 enabled the examination of thermochromism over the wide temperature range of 10 to 50 °C. The CPS-100, which can control the temperature of multiple
samples concurrently, enabled a more efficient investigation of thermochromism. This shows how selecting the right equipment for the application enables optimal temperature-controlled measurements.
