News from LabRulezICPMS - Library Week 32, 2024

Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week 32, 2024? Check out new documents from the field of spectroscopy, especially ICP/MS techniques!

👉 SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT ICPMS AND RELATED TECHNIQUES

👉 Need info about different analytical techniques? Peek into LabRulezLCMS or LabRulezGCMS libraries.

1. Metrohm: OMNIS NIRS: An efficiency boost for your laboratory

• Technical note

Routine lab analysis – simplified with OMNIS NIRS

Near-infrared spectroscopy (NIRS) is an analytical technique used to determine multiple parameters in samples quickly without requiring any chemicals. Determinations can be performed in liquids, pastes, and solids with this non-destructive method.

Many industries benefit from using NIRS in their laboratory workflows. Time and cost savings are two of the most convincing arguments for adopting NIRS in the laboratory. It is also easy to use, even for non-technical operators.

This White Paper discusses the concept and benefits of NIR spectroscopy, supplemented with the use of the Metrohm NIR solution, OMNIS NIRS, in several real-life laboratory application examples. Applications from the petrochemical, food and beverage, semiconductor, and** pharmaceutical industries** are used to demonstrate the unique functionalities of OMNIS NIRS in different situations.

SUMMARY

With OMNIS NIRS, users get a flexible, modular analytical solution which is suitable for many industries. Unique functionalities include:

• automatic model development (OMD)
• a high measurement speed
• the possibility to recognize sample insertion and removal
• sophisticated temperature control
• the ability to combine different analytical technologies from a single manufacturer - even in an automated system

Boost the efficiency of your laboratory with OMNIS NIRS.

2. Thermo Fisher Scientific: Analysis of process water from hydrogen fuel cells using triple quadrupole inductively coupled plasma mass spectrometry (ICP-MS)

• Application

Goal: To demonstrate the analysis of process water from hydrogen fuel cells for inorganic trace contaminants with high sensitivity and accuracy using triple quadrupole ICP-MS.

Keywords: Fluorine, fuel cell, high resolution, ICP-MS, KED, PEM, process water, triple quadrupole, TQ-O2 mode

Conclusions: The iCAP TQe ICP-MS was employed to analyze 53 elements including fluorine in process water derived from hydrogen fuel cells. Among the analytes, several critical interferences can cause unexpected bias, and these were investigated closely for effective and complete removal by means of selective collision / reaction cell reactions with oxygen. This study also included the development of a method for the analysis of fluorine, generally only possible in an indirect measurement. This analytical method was rigorously tested, and the results obtained clearly demonstrate the fowling analytical advantages:

• The iCAP TQe ICP-MS operated in TQ-O2 and He KED modes allowed the analysis of 53 elements in relevant sample matrices over a wide concentration range. For minor elements, the method was tested over 4 orders of magnitude (from 0.01 to 100 µg·L-1), whereas major elements were tested between 1 to 100 µg·L-1.
• Using a high throughput analysis approach, with a new autosampler equipped with a Step Ahead feature for minimizing total analysis time, all elements relevant for the development of hydrogen fuel cell technology could be measured accurately with low detection limits.
• The use of TQ-O₂ mode provided advanced performance for eliminating the polyatomic interferences of phosphorus, sulfur, silver, and cadmium in the simulated hydrogen fuel cell process water. This covered both polyatomic interferences as well as overlaps created by intense signals from isotopes of elements present in high concentrations.
• The iCAP TQe ICP-MS offers the flexibility to choose high resolution for the Q1 and Q3 quadrupoles, enabling complete elimination of polyatomic interference and isobaric interferences.
• The feasibility of fluorine analysis was demonstrated using an indirect method after complexation with barium. The iCAP TQe ICP-MS showed accurate and precise determination of fluorine as proven by the spike recovery tests performed.
• Excellent stability performance was obtained with the iCAP TQe ICP-MS together with excellent CCV and spike recovery results over a 3-hour run without internal standard correction. This provides the advantage of avoiding potential contamination from addition of the internal standard solution.

3. Thermo Fisher Scientific: Iron and steel - ARL iSpark Plus Optical Emission Spectrometer

• Application

Basic inclusion analysis

Non-metallic inclusions dramatically affect steel properties and cause process issues like nozzle clogging. The costs associated with bad steel properties, process issues or customer complaints may amount to several hundred thousand dollars every year. Controlling the formation and the modification of non-metallic inclusions has therefore become essential to the production of modern steels as demanded by today’s markets.

The Thermo Scientific ARL iSpark Plus is a high-end metal analyzer that allows precise and accurate elemental analysis of steel. It also enables ultra-fast analysis of non-metallic inclusions, enabling a steel plant to control steel quality and production process even more effectively, and considerably reduce the costs associated with unwanted inclusions.

The Basic Inclusion Analysis Spark-DAT (Spark Data Analysis and Treatment) option is the entry-level method for standard inclusion analysis in low alloy steel. It reports the amounts of some of the most common types of non-metallic inclusions together with the elemental concentrations, helping steel plants to guarantee the quality and the properties of the steel product, as well as the smooth running of the production process.

Benefits

• Ultra-fast evaluation of some main inclusion types
• Close to real-time inclusion check in up to hundreds of samples a day
• More effective control of inclusiondependent steel properties
• Helps reduce the number of costly issues caused by inclusions

4. Agilent Technologies: Detection of Endangered Species Using the Agilent Resolve Raman Analyzer

• Application

Abstract: The Agilent Resolve handheld Raman system is a versatile analyzer that can be deployed on location to identify a broad range of materials. It uses traditional surface analysis mode and through-barrier mode through Agilent's proprietary spatially offset Raman spectroscopy (SORS) technology. SORS enables samples that are concealed behind barriers such as colored and opaque plastics, paper, and highly pigmented paints and varnishes to be identified. This application note details how the Resolve Raman system can be used to detect concealed endangered species products using SORS. Data are presented that show the effectiveness of Resolve operating in traditional surface mode to distinguish ivory from a plastic substitute. Further analysis of endangered animal products using surface mode enabled the division of animal products into two broad categories: mineral-based and protein-based. Principal components analysis (PCA) was used to further differentiate the protein-based samples, which included pangolin scale, rhino horn, dried seahorse, and totoaba fish bladder, based on their spectral differences.

Conclusion: The Agilent Resolve handheld Raman analyzer includes various spectral libraries that enable the identification of a broad range of chemicals and materials. This study has shown the application of the instrument and the SORS technique for the detection of endangered animal species. Using a combination of conventional surface and through-barrier modes of analysis, Raman spectroscopy and SORS technology can be used to:

• Identify ivory through layers of paint and varnish.
• Differentiate plastic substitute materials from authentic ivory and bone.
• Distinguish between mineral-based animal products, such as ivory and armadillo scale, from protein-based animal products, such as rhino horn and pangolin scales.

The simple-to-use Resolve handheld Raman analyzer with SORS capability can provide complimentary data to help detect and identify endangered animal-derived samples.

5. Agilent Technologies: Verification of Raw Materials for Synthetic Peptide Production with the Agilent Vaya Raman System

• Application

Abstract: Advancements in the manufacturing technology of peptide drug products have enabled large-scale synthetic peptide production, producing high-purity synthetic peptides in bulk. The widespread demand for glucagon-like peptide receptor agonists (GLP-1 RAs) has put pressure on synthetic peptide manufacturing capacity and revealed the need for efficient and scalable tools. The Agilent Vaya Raman raw material identity verification system enables uniquely efficient raw material verification due to its through-container identification capabilities. This application note showcases Vaya's successful through-container identification and differentiation of key building blocks for synthetic peptide manufacturing: fluorenylmethoxycarbonyl (Fmoc)-protected amino acids.

Conclusion: The increasing demand for peptide biologics, such as GLP-1 receptor agonists, is expected to continue growing and outpacing current manufacturing capacity. To effectively meet demand, scalable solutions like the Agilent Vaya Raman raw material identity verification system introduce efficiencies to avoid bottlenecks that could be faced in raw material identification and regulatory-enforced verification. Additionally, the Vaya's ability to perform nondestructive, noninvasive identification ensures that raw materials are transferred expediently to production while preserving their integrity.