<p><span><strong>Sabina Cerulová originally planned to study veterinary medicine, but coincidence, the covid‑19 pandemic, and her bachelor’s project led her to research at RECETOX. Today, as a PhD student, she studies a rare genetic mutation responsible for severe symptoms in a specific patient, and she works with animal models, microbiome, and advanced imaging methods. What motivates her in science is the variety of work, the opportunity to constantly learn, and the hope that her work will one day help real people.&nbsp;</strong></span></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/RECETOX_MUNI_Ph_D_studentka_Sabina_Cerulova_Veda_da_strasne_moc_ale_strasne_moc_si_taky_vezme_Musi_vas_to_bavit_2_1ad2382856.jpeg" alt="RECETOX-MUNI: PhD student Sabina Cerulová: Science gives you so much, but it also takes a lot — you really must enjoy it" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_RECETOX_MUNI_Ph_D_studentka_Sabina_Cerulova_Veda_da_strasne_moc_ale_strasne_moc_si_taky_vezme_Musi_vas_to_bavit_2_1ad2382856.jpeg 117w," sizes="100vw" width="738" height="984"></p><h5><strong>How did you get into studying biochemistry and later into research at RECETOX?</strong></h5><p><span>I went to grammar school and for a long time I had no idea what exactly I wanted to do. It wasn’t until my final year that I realized I was drawn to veterinary medicine. But high school was wild. I had good grades, but I didn’t study much, and I thought the entrance exams would be similar. I was very wrong.&nbsp;</span></p><p><span>I applied to veterinary schools and biochemistry at the Faculty of Science, where I was luckily accepted, so I enrolled. Originally, I planned to transfer to veterinary medicine the next year, but then covid came, and admissions were based on high school grades, usually only straight A’s, so I didn’t get in.&nbsp;</span></p><p><span>In my second year, I started working on my bachelor’s thesis, and something just clicked. I got better at it, I understood more, my grades improved, and I decided to finish my bachelor’s degree. And then I was offered an amazing project.&nbsp;</span></p><h5><strong>Before we get to that project, what did you work on in your bachelor’s thesis</strong></h5><p><span>My bachelor’s thesis focused on analyzing the microbiome in the root canal of teeth in patients with apical periodontitis. I worked on it here at RECETOX under Associate<strong> Professor Petra Bořilová Linhartová</strong>. It was incredibly interesting — completely new work, new analyses. Because of covid, we had fewer lab classes, but I still really enjoyed it. After my bachelor’s, I received an offer from my supervisor, who knew I was interested in animals and veterinary science. For my thesis, she offered me the project we’ve already mentioned, which we work on in collaboration with the<strong> Institute of Histology and Embryology</strong>, in <strong>Associate Professor Křivánek’s group</strong>. They work with animal models, mainly mice, and study the effect of a genetic mutation found in a specific patient.&nbsp;</span></p><h5><strong>Why were you so drawn to animals? Have you ever considered studying medicine?&nbsp;</strong></h5><p><span>I’ve been close to animals since I was little. I used to ride horses, and at home we had hamsters, chinchillas, cats, and dogs. Everyone asked me why I didn’t go into medicine, but I guess I just like animals more than people (laughs). I liked the idea of having my own veterinary practice and being close to them.&nbsp;</span></p><p><span>Biochemistry was more of a backup plan; I didn’t really know what I was getting into. And I don’t regret it. Veterinary medicine will probably always be a dream, but I’m glad I stayed here.&nbsp;</span></p><h5><strong>Could you describe the project in more detail? If I understand correctly, you’re continuing the same topic in your dissertation.&nbsp;</strong></h5><p><span>Yes, that's right. Our research group collaborates with a hospital, which provided us with results from a patient who had numerous pathological findings since childhood: bone lesions, shortened tooth roots, enamel hypomineralization, joint pain, high phosphate levels in the blood.&nbsp;</span></p><p><span>Whole‑exome sequencing was performed, and a very rare mutation was identified in the gene that I study. In collaboration with other institutions, we created a mouse with the same point of mutation. It underwent phenotyping screening, and its symptoms were very similar to the patient’s. That was a huge success. Now we’re trying to further characterize the model and, in the future, test treatment options on it — diets, DNA modification, anything that could help not only her but also other patients with similar symptoms.&nbsp;</span></p><h5><strong>Do you work only with that one mutation, or with other models as well?</strong></h5><p><span>Primarily, I focus on one specific point of mutation, but we also worked with knockout mice where the gene is completely switched off. The results were quite variable, so we now study both lines. Thanks to our collaborations, we also have access to data from other mouse models with mutations in genes closely associated with hyperphosphatemia, which helps us put our results into a broader context.&nbsp;</span></p><h5><strong>Are you planning to study additional patients as well?</strong></h5><p><span>Yes. We want to publish a paper on additional patients, especially those on dialysis, and examine their phosphate levels and potential genetic modifications. Phosphate is not routinely tested, so similar disorders may be hidden. We’d like to find out whether their problems could be related to this gene and thus make our project applicable to a larger group of patients.&nbsp;</span></p><h5><strong>Do you use imaging methods? With what goal?</strong></h5><p><span>Yes. We wanted something non‑invasive, because microCT requires euthanizing the mice. In collaboration with the core facility, we’re testing MRI to observe manifestations of the mutation over time — in bones, soft tissues, kidneys. We obtained a grant for this, currently for one year. We need to observe progression, and then we can apply for further funding.&nbsp;</span></p><h5><strong>What surprised you most about working with animal models?&nbsp;</strong></h5><p><span>The time. Everything takes so long. Mice are living organisms, sometimes they’re born and then eat each other. It’s unpredictable. And we got our first shock when we were expecting offspring and nothing happened. Only later we found out that males with this mutation are infertile. As an animal lover, I cried over the first mouse I lost. But then you remind yourself that you're doing this to help patients. And you look for ways to use as few mice as possible.&nbsp;</span></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/RECETOX_MUNI_Ph_D_studentka_Sabina_Cerulova_Veda_da_strasne_moc_ale_strasne_moc_si_taky_vezme_Musi_vas_to_bavit_1_787855e117.jpeg" alt="RECETOX-MUNI: PhD student Sabina Cerulová: Science gives you so much, but it also takes a lot — you really must enjoy it" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_RECETOX_MUNI_Ph_D_studentka_Sabina_Cerulova_Veda_da_strasne_moc_ale_strasne_moc_si_taky_vezme_Musi_vas_to_bavit_1_787855e117.jpeg 117w," sizes="100vw" width="450" height="600"></p><h5><strong>Why don’t you use vitro approaches instead, such as testing outside a living organism?&nbsp;</strong></h5><p><span>Because of speed and complexity. Mice reproduce quickly, live for about two years, and share 99% of their genes with humans. Using cells would be much slower, and we wouldn’t see the full picture of how the organism behaves.&nbsp;</span></p><h5><strong>What do you enjoy most about the work?</strong></h5><p><span>The variety. That I can tailor my day to what I have the capacity for. Sometimes I prepare samples for sequencing, sometimes I do analyses, sometimes I teach. I enjoy constantly learning and the diversity of tasks.&nbsp;</span></p><h5><strong>What is the hardest part of PhD studies for you?</strong></h5><p><span>Time management. I’m not good at it, and I’m very grateful to my supervisor, who helps me stay on track. And also, not losing myself in the work — I need to have a personal life. I do this because I enjoy it, but I don’t want to burn out.&nbsp;</span></p><h5><strong>How do you view working with students?</strong></h5><p><span>I enjoy it, but it’s demanding. Sometimes students mistake me for one of them (laughs), because I look young. And they’re very motivated — sometimes I feel like they know more than I do. But it has taught me a lot about patience and confidence. I really enjoy taking lectures.</span></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/RECETOX_MUNI_Ph_D_studentka_Sabina_Cerulova_Veda_da_strasne_moc_ale_strasne_moc_si_taky_vezme_Musi_vas_to_bavit_3_f7b11b8efa.jpeg" alt="RECETOX-MUNI: PhD student Sabina Cerulová: Science gives you so much, but it also takes a lot — you really must enjoy it" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_RECETOX_MUNI_Ph_D_studentka_Sabina_Cerulova_Veda_da_strasne_moc_ale_strasne_moc_si_taky_vezme_Musi_vas_to_bavit_3_f7b11b8efa.jpeg 156w," sizes="100vw" width="450" height="450"></p><h5><strong>What are you most proud of in your scientific journey so far?</strong></h5><p><span>My progress. I never imagined myself in academia. Looking back, I’m grateful to the consultants on my bachelor’s thesis for their patience. Changing my approach and discovering that I enjoy it has moved me forward the most. I’m not focused on one specific result but on personal growth.&nbsp;</span></p><h5><strong>What motivates you to keep going?&nbsp;</strong></h5><p><span>The idea that one day it will work out. I try to stay positive, even though some days are tough and nothing goes according to plan.&nbsp;</span></p><h5><strong>Do you also engage in science outreach?</strong></h5><p><span>Yes. We do a lot, especially for children. I recently visited my hometown, Karviná. We have third graders, ninth graders… It’s great; the kids are enthusiastic. Outreaching is extremely important — showing that science is fun and needed everywhere.&nbsp;</span></p><h5><strong>And what is next after the PhD?</strong></h5><p><span>I don’t know. Maybe another PhD (laughs). But I certainly want to stay in science.</span></p><h5><strong>What advice would you give to young people considering a scientific career?</strong></h5><p><span>You must enjoy it. Science gives you so much, but it takes a lot as well. You must be passionate about it and find a topic that’s truly yours.</span></p>

PhD student Sabina Cerulová: Science gives you so much, but it also takes a lot — you really must enjoy it

<p><strong>This study investigates the concentrations and bioaccessibility of essential trace elements (Co, Cu, Fe, Mn, Zn) in commonly consumed edible plants. Using multiple physiologically relevant extraction methods, the work assesses both total and bioaccessible fractions to better estimate dietary intake.</strong></p><p>Monte Carlo simulations revealed variability in nutrient exposure, with most intake levels within recommended ranges but some cases indicating potential deficiencies or excess. The results highlight the importance of incorporating bioaccessibility and realistic exposure modeling into nutritional assessments and dietary risk evaluations.</p><blockquote><h4><strong>The original article</strong></h4><h4><a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.jafc.5c10365"><strong>Essential Trace Elements in Edible Plants: Balancing Nutritional Benefits and Potential Health Risks</strong></a></h4><p>Agata Stolecka*, Pilar Ortiz Sandoval, and Agnieszka Gruszecka-Kosowska</p><p>J. Agric. Food Chem. 2026, 74, 8, 7084–7097</p><p><a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1021/acs.jafc.5c10365">https://doi.org/10.1021/acs.jafc.5c10365</a></p><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/"><strong>CC-BY 4.0</strong></a></h6></blockquote><p><strong>Selected sections from the article follow. Formats and hyperlinks were adapted from the original.</strong></p><div><p>Many trace elements are essential micronutrients required in minute amounts, yet they are indispensable for the structural and functional integrity of living organisms. <a href="javascript:void(0);">(1)</a> As a subgroup of micronutrients, alongside vitamins and antioxidants, they play vital roles in supporting regenerative processes, defending against oxidative stress, and maintaining immune function in metabolically active tissues. <a href="javascript:void(0);">(2)</a> Despite their low concentrations in biological systems, they serve as cofactors for numerous enzymatic reactions and contribute to essential physiological processes such as oxygen transport, redox balance, and cellular metabolism. <a href="javascript:void(0);">(3−5)</a> In line with the WHO <a href="javascript:void(0);">(6)</a> and Frieden <a href="javascript:void(0);">(7)</a> classifications, this study focuses on the essential trace elements (ETEs), namely cobalt (Co), copper (Cu), iron (Fe), manganese (Mn), and zinc (Zn), all of which have well-established roles in human nutrition and are integral to maintaining both general and oral health. <a href="javascript:void(0);">(8)</a> Deficiency in the aforementioned elements can lead to a range of health problems. Co, as a component of vitamin B12, is critical for red blood cell formation and neurological function; its deficiency may result in megaloblastic anemia and neurological impairments. <a href="javascript:void(0);">(9)</a> Cu is essential for iron metabolism, antioxidant defense, and connective tissue synthesis; inadequate intake can lead to anemia, weakened immunity, impaired growth and development (especially in children), osteoporosis, abnormal cholesterol metabolism, and neurological disturbances. <a href="javascript:void(0);">(10)</a> Fe deficiency remains one of the most widespread nutritional problems globally and is the leading cause of anemia, fatigue, and impaired cognitive and immune function. <a href="javascript:void(0);">(11)</a> Mn is involved in bone development, metabolism, and antioxidant enzyme activity; low levels can impair growth, fertility, and glucose regulation. <a href="javascript:void(0);">(12)</a> Zn is vital for immune response, wound healing, and DNA synthesis; deficiency can cause growth retardation, delayed sexual maturation, and increased susceptibility to infections. <a href="javascript:void(0);">(13)</a> While maintaining adequate levels of these trace elements is crucial for overall health and physiological functioning, excessive intake may also pose health risks. <a href="javascript:void(0);">(14,15)</a> The margin between beneficial and toxic doses is broad for some bioelements but narrow for others, highlighting the need for careful monitoring of their concentrations in the food supply. <a href="javascript:void(0);">(16)</a></p><p>The mineral content of edible plants, a major dietary source of essential elements, is influenced by numerous factors, including plant genotype (cultivar), soil properties, weather conditions, and agricultural practices such as fertilizer application during fruiting and maturation stages. <a href="javascript:void(0);">(17)</a> Consequently, the concentration of trace elements in plant-based foods can vary widely, affecting both their nutritional value and their potential to contribute to dietary exposure risks. <a href="javascript:void(0);">(18)</a> Customarily, the assessment of ETEs in edible plants has relied on total concentration (TC) measurements, which assume complete gastrointestinal absorption. <a href="javascript:void(0);">(19−21)</a> While this approach is commonly used to estimate nutritional contributions, it does not account for the fact that only a fraction of the ingested element may be bioaccessible and available for absorption during digestion. As a result, it may lead to either over- or underestimation of both health benefits and potential adverse effects. To better reflect human exposure, a range of in vitro extraction methods have been developed to simulate the bioaccessibility of elements under gastric and/or intestinal conditions. <a href="javascript:void(0);">(22,23)</a> These methods vary in terms of chemical reagents, pH levels, and complexity. For example, the BCR 3-step extraction targets chemical elements associated with different binding forms, <a href="javascript:void(0);">(24)</a> while the USEPA 1340 simulates acidic gastric conditions relevant to lead bioaccessibility. <a href="javascript:void(0);">(25)</a> More advanced protocols, like ISO 17924:2018 and the BARGE Unified Bioaccessibility Method (UBM), replicate digestive phases using physiologically relevant fluids. <a href="javascript:void(0);">(22,26)</a> Simpler methods, such as SBET and PBET, aim to simulate one or both digestion phases under controlled laboratory conditions. <a href="javascript:void(0);">(27,28)</a> In the context of ETEs such as Co, Cu, Fe, Mn, and Zn, evaluating bioaccessibility is crucial for accurate dietary intake estimates. These elements play key roles in numerous physiological functions, and both deficiencies and excess intake can affect human health. However, limited data exist on how the choice of extraction method affects estimates of their dietary contribution and associated noncarcinogenic risks.</p><p>To address this gap, the present study evaluates Co, Cu, Fe, Mn, and Zn concentrations in vegetables, fruits, and cereals using seven extraction methods. The results are used to estimate both the nutritional contribution and the potential health risks from dietary intake. To incorporate variability and uncertainty in dietary exposure, such as metal concentrations, consumption patterns, and body weight, Monte Carlo simulations were applied. This probabilistic approach enables a more robust evaluation of nutrient intake and safety, providing insights that can inform dietary guidelines and regulatory decisions. The main objective of the study was to investigate how different extraction methods, simulating gastrointestinal bioaccessibility, may impact the estimation of both nutritional contribution and potential risks. In this study, the contribution of five ETEs, namely Co, Cu, Fe, Mn, and Zn, to a healthy diet and the potential health risks associated with their intake were evaluated. The detailed objectives of the study were to 1) investigate concentrations of Co, Cu, Fe, Mn, and Zn in three plant categories, namely vegetables, fruits, and cereals, using the following seven extraction methods: Total Content (TC), three-step extraction procedure (BCR), USEPA SW-846 Test Method 1340: In Vitro Bioaccessibility Assay for Lead in Soil (USEPA), ISO 17924:2018 Soil quality─Assessment of human exposure from ingestion of soil and soil material─procedure for the estimation of the human bioaccessibility/bioavailability of metals in soil (ISO), the BARGE (Bioaccessibility Research Group of Europe) unified bioaccessibility method (UBM), Simple Bioavailability Test (SBET), and Physiologically Based Extraction Test (PBET); 2) use Monte Carlo simulations to estimate the nutritional contribution and noncarcinogenic risk from dietary intake of these ETEs, based on Polish food consumption data; and 3) address variability and uncertainty in dietary exposure through probabilistic modeling with Monte Carlo simulations.</p><h4><strong>2. Materials and Methods</strong></h4><h5><strong>2.3. Instrumental Analysis</strong></h5><p>The concentrations of investigated ETEs were determined by inductively coupled plasma-mass spectrometry (<strong>ICP-MS) (ELAN 6100</strong>; PerkinElmer, Waltham, MA, USA) in the case of Co or inductively coupled plasma optical emission spectrometry (<strong>ICP-OES) (OPTIMA 7300DV</strong>; PerkinElmer, Waltham, MA, USA) in the case of Cu, Fe, Mn, and Zn according to the United States Environmental Protection Agency (USEPA) 6020B and ISO 17294-2:2003 protocols.</p><h4><strong>4. Results and Discussion</strong></h4><h5><strong>4.2. Estimated Nutrient Intake (ENI)</strong></h5><p>Estimated Nutrient Intake of ETEs (50th percentile) from all edible plants intake from Monte Carlo simulations is shown in <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.jafc.5c10365#fig2">Figure 2</a>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/J_Agric_Food_Chem_2026_74_8_7084_7097_Figure_2_Estimated_Nutrient_Intake_ENI_of_ET_Es_based_on_the_50th_percentile_of_all_investigated_edible_plant_intake_from_Monte_Carlo_simulations_7ad01eb189.jpg" alt="Anal. Chem. 2026, 98, 9, 6589–6597: Figure 2. Evaluation of CoD screening prediction performance of LCMS-Net in comparison to benchmark models. The prediction performance of a classifier is measured by accuracy, macro F1-score, macro sensitivity, and macro specificity over five model runs. The error bars represent the standard deviations between model runs." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_J_Agric_Food_Chem_2026_74_8_7084_7097_Figure_2_Estimated_Nutrient_Intake_ENI_of_ET_Es_based_on_the_50th_percentile_of_all_investigated_edible_plant_intake_from_Monte_Carlo_simulations_7ad01eb189.jpg 245w," sizes="100vw" width="2092" height="852"></p><h5><strong>4.3. Human Health Risk Assessment</strong></h5><p>Noncarcinogenic risk (HQ) values for 5th, 50th, and 95th percentiles of the determined concentrations of investigated ETEs in vegetables, fruits, and cereals calculated using Monte Carlo simulations are presented in <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.jafc.5c10365#fig3">Figure 3</a>, and the same values for the sum of edible plants consumed are presented in <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.jafc.5c10365#fig4">Figure 4</a>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/J_Agric_Food_Chem_2026_74_8_7084_7097_Figure_3_Noncarcinogenic_HQ_risk_values_for_investigated_trace_elements_from_various_extraction_methods_4f2d9ee942.jpg" alt="J. Agric. Food Chem. 2026, 74, 8, 7084–7097: Figure 3. Noncarcinogenic (HQ) risk values for investigated trace elements from various extraction methods according to Polish statistical consumption of edible plants, vegetables, fruits, and cereals separately." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_J_Agric_Food_Chem_2026_74_8_7084_7097_Figure_3_Noncarcinogenic_HQ_risk_values_for_investigated_trace_elements_from_various_extraction_methods_4f2d9ee942.jpg 110w," sizes="100vw" width="1822" height="2583"></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/JAGRIC_2_76102decb2.jpg" alt="J. Agric. Food Chem. 2026, 74, 8, 7084–7097: Figure 4. Noncarcinogenic (HQ) risk values for investigated trace elements from various extraction methods according to Polish statistical consumption of the sum of edible plants." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_JAGRIC_2_76102decb2.jpg 245w," sizes="100vw" width="1877" height="896"></p><p>Due to concentrations below the LOQ, HQ values could not be calculated for several ETEs in vegetables, fruits, and cereals across the different extraction methods. For instance, Co in cereals yielded measurable concentrations only under the TC method, whereas Fe in vegetables was consistently above the LOQ for all extraction methods, allowing HQ estimation in each case. These results indicate that the efficiency of element recovery is both element- and matrix-dependent and that no single extraction protocol is universally optimal for all ETE–matrix combinations.</p><p>Considering HQs that were successfully simulated across most elements (particularly Co, Cu, and Fe), the TC method produced the highest HQ values, exceeding the risk threshold (HQ = 1) at the 95th percentile for Co and Cu. The 95th percentile HQ for Co under TC reached 1.05 in vegetables and 2.77 in fruits, staying below the safety threshold for cereals, while for Cu it reached 4.30 in vegetables, 1.83 in fruits, and 1.08 in cereals, indicating potential overestimation if full bioavailability is assumed. For Fe the risk was lower, staying below the threshold in all cases, but TC still displayed the highest values in most cases with the 95th percentile HQ reaching 0.66 in vegetables, 0.39 in fruits, and 0.43 in cereals. The only exception to this trend was the 95th percentile risk for Fe in vegetables, where the ISO intestinal yielded 0.87.</p><p>In contrast, bioaccessibility-based methods (e.g., UBM, PBET, SBET, and BCR) generally generated lower HQs, often falling below the threshold. For example, 95th percentile Co HQ values under UBM gastric and intestinal extractions were ∼0.75 in vegetables, while USEPA was 0.56 and SBET, PBET, and BCR yielded &lt;0.50. A similar trend was observed for Cu, where UBM intestinal yielded 0.58 vs 4.30 under TC.</p><p>However, Mn and Zn showed distinctively different patterns. For Mn in cereals, the USEPA method produced a median HQ of 5.18 and 15.7 at the 95th percentile, far higher than all the other methods, including the TC method (median 0.32). For Zn in vegetables, ISO gastric (0.39) and intestinal (0.37) extractions gave median HQs higher than that of TC (0.27).</p><h5><strong>4.7. Implications</strong></h5><p>This study shows that the extraction method choice greatly affects Estimated Nutrient Intake (ENI) and dietary exposure assessments of essential trace elements in edible plants. Simulated gastrointestinal methods, reflecting human physiology, generally report lower concentrations than the TC method, indicating that relying on total concentrations alone can overestimate intake by ignoring bioaccessibility, a key factor in accurate risk assessment.</p><p>ENI assessments help evaluate nutrient over- or underexposure but may miss health risks. Monte Carlo-based Hazard Quotient (HQ) analysis provides a more precise dietary risk estimate by accounting for bioavailability and intake variability. This combined approach is crucial for essential elements, balancing deficiency and toxicity concerns.</p><p>For most elements, ENI values matched recommended intakes, but variations occurred by element, food group, and extraction method. Some simulations indicated possible insufficient intake risks (e.g., Co and Fe in certain plants), while others showed overexposure risks (notably, Cu and Mn) when assuming full bioavailability from total concentrations. These results highlight the need to include realistic bioaccessibility in dietary nutrient assessments.</p><p>Comparing HQ values across plant types and elements, the study highlights how vegetables, fruits, and cereals contribute differently to nutritional risk. This comprehensive approach offers a clearer picture of dietary exposure than analyses based on only total concentrations or single foods. While most essential trace elements posed no immediate risk under realistic bioaccessibility assumptions, Co and Cu results indicate a potential for excessive intake.</p><p>Our results revealed that UBM, ISO, PBET1, and BCR1 methods provide the most reliable estimates of ETE bioaccessibility in edible plants, while TC tends to overestimate and simpler methods (SBET, PBET2) may underestimate exposure. Incorporating bioaccessibility-corrected data and considering food matrix-specific factors are essential for accurate dietary risk assessments and effective public health management.</p><p>In conclusion, these findings highlight the importance of incorporating physiologically relevant extraction methods into dietary risk assessment to complement the total concentration data in food safety and nutrition research. The results may inform future regulatory frameworks, dietary guidance, and fortification strategies. Further research should focus on validating in vitro bioaccessibility with in vivo evidence, exploring nutrient–contaminant interactions, and expanding assessments across diverse diets and populations to strengthen the evidence base for nutrition policy development.</p></div>

Essential Trace Elements in Edible Plants: Balancing Nutritional Benefits and Potential Health Risks

<p><strong>In the week from April 20, the following webinars await you in the field of atomic and molecular spectroscopy and spectrometry</strong></p><blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4><p><strong>👉 Search and filter in the largest global database</strong> with over <strong>5 500 GC, LC, MS and spectroscopy webinars</strong>.</p></blockquote><h5><strong>1. Metrohm: Copper deposition baths: Advanced analytical solutions for development and monitoring</strong></h5><ul><li>Tu, 21.4.2026 09:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6123">Registration</a></li></ul><p>Discover a multi-method approach to copper plating bath analysis combining titration, CVS, XRF, and pH measurement for improved process control, data reliability, and production quality.</p><h5><strong>2. Thermo Fisher Scientific: Lunch and Learn Tips and Tricks Series: Qtegra Part 2</strong></h5><ul><li>Tu, 21.4.2026 12:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/5976">Registration</a></li></ul><p>Part two explores efficient Qtegra ISDS workflows and integrated tools designed to improve laboratory productivity and enhance trace elemental analysis quality.</p><h5><strong>3. C&amp;EN: NMR-augmented Workflows: Most Modern Integration into Laboratories</strong></h5><ul><li>Tu, 21.4.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6107">Registration</a></li></ul><p>From high resolution instruments in smaller footprints to smarter software that enhances data quality and streamlines analysis.</p><h5><strong>4. Agilent Technologies: Accurate Determination of Chlorine Isotope Ratio Analysis by 8900 ICP-MS</strong></h5><ul><li>Tu, 21.4.2026 20:30 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6047">Registration</a></li></ul><p>This session discusses techniques for low level chlorine analysis and isotope ratio on the 8900 QQQ-ICPMS.</p><h5><strong>5. SelectScience: What’s in your hydrogen? Analytical toolkits for fuel purity analysis</strong></h5><ul><li>We, 22.4.2026 10:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6055">Registration</a></li></ul><p>Join this dual-session webinar on hydrogen impurity testing and ISO 14687 fuel quality. Learn how GC, GC-MS, IC, and FTIR workflows support safe, compliant hydrogen production and fuel-cell applications.</p><h5><strong>6. Bruker: Introduction to Photothermal AFM-IR for Infrared Spectroscopists</strong></h5><ul><li>We, 22.4.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6109">Registration</a></li></ul><p>With photothermal atomic force microscope infrared spectroscopy (AFM-IR), chemical identification at the nanoscale is achieved by measuring local IR spectra directly at the AFM tip.</p><h5><strong>7. Mettler-Toledo: How to Determine Specific Heat Capacity by DSC</strong></h5><ul><li>Th, 23.4.2026 16:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/5736">Registration</a></li></ul><p>Explore six DSC techniques for measuring specific heat capacity and understand its importance in material performance, processing, and safety. Join the live webinar.</p><h5><strong>8. Bruker: EDS Analysis of Fibers, Polymers, and Ceramics – Best Practices</strong></h5><ul><li>Th, 23.4.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6111">Registration</a></li></ul><p>Different EDS measurement approaches using conventional geometry and an annular approach (QUANTAX FlatQUAD) making the best choice for challenging analytical tasks.</p>

Webinars LabRulezICPMS Week 17/2026

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RECETOX (Research Centre for Toxic Compounds in the Environment) is an independent department of the Faculty of Science of Masaryk University in Brno, which has been established in 1983. RECETOX is focused on the research and education in cross-cutting area of Environment and Health. It addresses interactions among chemicals, environment, and biological systems, including consequences at local, regional, and global levels.

RECETOX - Centrum pro výzkum toxických látek v prostředí

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

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Mettler-Toledo

Anton Paar

Agilent Technologies

SPECTRO Analytical Instruments

Bruker

LECO

Thermo Fisher Scientific

<header><h4><strong>How to Use Thermal Analysis to Improve Safety in the Chemical Industry</strong></h4></header><main><div><div><h5><strong>Program</strong></h5><ul><li>Basic concepts of safety analysis: time to maximum rate, criticality of a reaction</li><li>Thermal analysis and reaction calorimetry applications</li><li>Industry applications: differential scanning calorimetry (DSC)</li><li>Industry applications: thermogravimetry (TGA)</li><li>Interactive Q&amp;A session</li></ul></div></div><div><div><div><p>Accident prevention in chemical production plants is a critical topic, and avoiding incidents that could cause casualties or environmental harm is paramount. Thermal runaway reactions are often at the root of such incidents and must be effectively managed. By using thermal analysis and reaction calorimetry, you can easily assess the thermal safety of chemicals and processes. This means that thermal hazards can be identified at an early stage of process development, saving time, costs, and lives.</p><p>Join this live webinar to learn how thermal analysis techniques—DSC and TGA—are used to investigate hazardous compounds and conduct safety studies in the chemical industry. We will present real-life examples of safety investigations using these techniques.</p><p>Don’t miss the live <strong>Q&amp;A session</strong> where you can ask our experts your own questions. Secure your spot today.</p><h4><strong>How to Use Thermal Analysis for Safety Assessment</strong></h4><ul><li><strong>DSC</strong> is typically used to investigate the thermal safety aspects of individual chemicals. Reaction calorimetry is used to provide safety information about processes, for example, to determine the heat flow during the dosing of reactants or during stirring.</li><li><strong>TGA </strong>is useful for determining evaporation, desorption, and vaporization behavior, as well as thermal stability and the decomposition kinetics.</li><li><strong>Evolved gas analysis</strong> techniques are used to gain information about the products evolved during a decomposition reaction. The TGA module is combined with a technique, such as FTIR, MS, or GC-MS.</li><li><strong>TGA/DSC</strong> combines two different thermal analysis techniques to provide complementary information about a sample's thermal behavior.</li></ul><p>Don’t miss this opportunity to gain in-depth knowledge on safety evaluations for the chemical industry.&nbsp;</p></div><div><div data-advanced-option="false" data-has-preview-image="false" data-video-id="" data-component-id="2110920040"><div style="max-width:1px;width:100%;" id="mediaContainerWrapper_2110920040"><div style="height:1px;width:1px;" data-external-url="" id="mediaContainer_2110920040" data-advanced-option="false" data-width="1" data-height="1" data-video-id="">&nbsp;</div></div></div></div></div></div></main><div><div><div data-advanced-option="false" data-has-preview-image="false" data-video-id="" data-component-id="2110920040"><blockquote><div><strong>Presenter: </strong>Dr. Teresa Dennenwaldt</div><p>Dr. Teresa Dennenwaldt obtained her PhD in chemistry in 2013 and completed a postdoc at the Ecole Polytechnique Fédérale de Lausanne, Switzerland in the field of electron microscopy and spectroscopy. In 2018, she joined METTLER TOLEDO as an application specialist for Thermal Analysis. In her current position, she expertly uses, teaches, and supports DSC, TGA, TMA, and DMA instruments at the METTLER TOLEDO head office in Switzerland.</p></blockquote></div></div></div>

Mettler Toledo: Thermal Analysis for Safety Evaluation of Chemical Processes

Thermal Analysis for Safety Evaluation of Chemical Processes

Join this webinar to explore how thermal analysis helps identify thermal hazards, improve process safety, and prevent runaway reactions in chemical production.

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><h4><strong>Evaluating Quality and Composition through Glow Discharge Optical Emission Spectrometry, Metallography and Hydrogen Analysis</strong></h4><p><strong>Explore how modern characterization tools, Glow Discharge Optical Emission Spectrometry, metallography, and Hydrogen analysis, work together to solve common aluminum alloy challenges. Attendees will learn how combining compositional analysis, microstructural evaluation, and hydrogen measurement provides a picture of alloy quality, defect formation, and processing consistency. Discover how an integrated, multimethod approach strengthens grade verification, improves root cause investigations, and supports high performance aluminum manufacturing.</strong></p><blockquote><p><strong>Presenter: </strong>Aaron Walczewski (Director of Product, LECO Corporation)</p><p><strong>Presenter: </strong>Ariyona Palmer (Application Scientist, LECO Corporation)</p><p><strong>Presenter:&nbsp;</strong>Lauren Heirty (Application Scientist, LECO Corporation)</p></blockquote></div></div></div>

LECO: Solving Aluminum Challenges with Modern Characterization Tools

Solving Aluminum Challenges with Modern Characterization Tools

Webinar on aluminum alloy quality using GD-OES, metallography, and hydrogen analysis for defect detection, grade verification, and process optimization.

Aluminum Challenges with Modern Characterization Tools

<div><p><strong>Join us for an exclusive webinar featuring two global pioneers in spatial chemical analysis: Jonathan Sweedler from the University of Illinois Urbana-Champaign and Carsten Hopf from the Center for Mass Spectrometry and Optical Spectroscopy (CeMOS) at Mannheim University.</strong></p><h4><strong>What you will learn:</strong></h4><ul><li>How advanced multimodal imaging workflows enable highly specific ROI-focused molecular imaging in complex tissues.</li><li>How combining QCL-based IR microscopy, fluorescence microscopy and MALDI Imaging allows rapid feature detection, and deeper molecular analysis.</li></ul><h4><strong>Who should join:</strong></h4><ul><li>Experienced MALDI Imaging users aiming to improve spatial specificity, molecular identification confidence, and sample throughput.</li><li>Scientists and researchers interested in multimodal imaging workflows that integrate IR and fluorescence microscopy to guide targeted MALDI Imaging.</li></ul><h4><strong>Topics covered:</strong></h4><ul><li>New MALDI Imaging strategies for ROI-specific molecular analysis.</li><li>Multimodal integration for rapid tissue screening and biological feature labeling.</li></ul><blockquote><p><strong>Presenter:</strong> Carsten Hopf, Ph.D.</p><p>Carsten Hopf is a Professor of Bioanalytics and Drug Discovery at Mannheim University of Applied Sciences and the Director of the Center for Mass Spectrometry and Optical Spectroscopy (CeMOS). A leader in MALDI Imaging, his work focuses on advancing various imaging modalities to map the spatial distribution of drugs, lipids, and proteins in tissues and cells for complex diseases, such as cancer and Alzheimer's.&nbsp;</p><p><strong>Presenter:</strong> Jonathan Sweedler, Ph.D.</p><p>Jonathan Sweedler holds the Chair in Chemistry at the University of Illinois Urbana-Champaign and is the Editor-in-Chief of Analytical Chemistry. He's a pioneer in analytical neurochemistry, focusing his research on developing ultrasensitive mass spectrometry and imaging tools to uncover the chemical secrets of individual cells and complex tissues.&nbsp;</p></blockquote></div>

Bruker: MALDI Imaging Becomes IR-resistible: Going Multimodal for Advanced Biomedical Insights

MALDI Imaging Becomes IR-resistible: Going Multimodal for Advanced Biomedical Insights

Webinar on multimodal imaging combining MALDI, IR, and fluorescence microscopy for precise ROI-based molecular analysis in tissues.

MALDI Imaging Becomes IR-resistible

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><p><strong>Join this webinar to learn how moisture and loss on ignition (LOI) measurements are used to assess the quality and handling of cement, fly ash, gypsum, and lime. Presenters will explain why controlling moisture, carbonation, and thermal decomposition is essential for maintaining material performance and meeting industry specifications.</strong></p><p>The session will introduce thermogravimetric analysis (TGA) as an automated approach for measuring mass changes over controlled temperature programs and atmospheres. Attendees will gain insight into TGA method development, sample preparation, and instrument operation, with reference to ASTM methods for combustion residues, flue gas desulfurization solids, hydrated lime, and hydraulic cement.</p><p>Through application examples and reference material data, the webinar will demonstrate how TGA supports repeatable, standards-based moisture and LOI determination. Participants will leave with a clearer understanding of how these measurements can be used to monitor raw materials, detect storage or handling issues, and ensure consistent cement and construction material quality.</p><blockquote><p><strong>Presenter: </strong>Jeffrey Gast (Lead Application Chemist, LECO)</p></blockquote></div></div></div>

LECO: Moisture and LOI Determination in Cement, Fly Ash, Gypsum, and Lime

Moisture and LOI Determination in Cement, Fly Ash, Gypsum, and Lime

Webinar on TGA for moisture and LOI testing in cement and construction materials, aligned with ASTM standards.

Moisture and LOI Determination in Cement, Fly Ash

<div><p><strong>During this webinar, Jimmy Fong, Director of Products and Technology at Bruker, will give an engaging presentation about the background of Bruker in two-photon imaging and the Ultima 2Pplus multiphoton microscope. He will also elaborate on the advantages of different modules, including developments in 3D holographic optogenetics enabled by the NeuraLight 3D Ultra spatial light modulator, voltage imaging collaborations for new data with the OptoVolt Module, and mesoscale imaging using the xView Module.</strong></p><h5><strong>Abstract</strong></h5><p>Two-photon (2P) microscopy has advanced our understanding of computation and connectivity in neuroscience. Through in-vivo calcium imaging at cell-resolution, scientists study brain activity from scales of dendritic spines to neuronal networks. Combined with optogenetics and voltage imaging, 2P microscopy offers new insights into dynamic interactions in neural circuits.</p><p>Learn about the history of 2P imaging, Bruker’s Ultima multiphoton systems, and a suite of modules that enhance research possibilities in neuroscience. These modules enable 3D holographic optogenetics with NeuraLight 3D Ultra, voltage imaging with OptoVolt, fast volumetric imaging with NeuraLeap, mesoscale imaging with xView, and more. Attendees will also be introduced to the Inverter Module, which provides new imaging capabilities of different biological samples.</p><blockquote><p><strong>Presenter:</strong> Jimmy Fong (Director, Products and Technology)</p><p>Jimmy Fong is the director of products and technology at Bruker with expertise in multiphoton imaging systems. He has a keen interest in bringing new microscopy technologies to the greater scientific community and has worked tirelessly with his colleagues to achieve this goal. He holds both a bachelor's and a master’s degree in biomedical engineering with a minor in computer sciences from the University of Wisconsin-Madison.</p></blockquote></div>

Bruker: Illuminating Brain Function through Two-Photon Microscopy: Calcium and Voltage Dynamics with Optogenetics

Illuminating Brain Function through Two-Photon Microscopy: Calcium and Voltage Dynamics with Optogenetics

Webinar on Bruker Ultima 2Pplus multiphoton microscopy and new modules for optogenetics, voltage imaging, and advanced neuroscience imaging.

Illuminating Brain Function through Two-Photon Microscopy

<div><h4><strong>Learn how to best use atomic force microscopy</strong></h4><p><strong>During this webinar, Bruker experts will give a general overview of best practices for sample preparation with atomic force microscopy (AFM), along with useful tips and tricks for achieving optimal results. They will also highlight a range of modes, accessories, and add-ons that significantly enhance the functionality of AFM beyond conventional imaging, without major upgrades.</strong></p><p>Extend your research capabilities with unique features:</p><ul><li>Environmental control options for temperature, humidity, pH, and CO<sub>2</sub></li><li>CellWizard Stage for automated, multi-chamber measurements</li><li>New modes, e.g., SmartMapping for increased ease, speed, and accuracy</li><li>AI and machine learning capabilities for autonomous measurements</li></ul><p>Atomic force microscopy (AFM) is a powerful tool, and a suite of advanced accessories makes it a highly versatile platform. Tailored configurations can address a diverse range of scientific applications and complex biological questions, from dynamic molecular mechanisms to protein folding events and cellular interactions.</p></div>

Bruker: Unlocking BioAFM Performance: From Sample Preparation to Advanced Accessories

Unlocking BioAFM Performance: From Sample Preparation to Advanced Accessories

Webinar on atomic force microscopy best practices, sample preparation, advanced modes, and AI-enabled AFM features for biological and materials research.

Unlocking BioAFM Performance

<div><div id="inner_content_body_text" data-content-id="394785"><p><strong>Join this free Anton Paar webinar to find out how to choose the right setup, avoid common measurement mistakes, and improve reproducibility in your lab viscosity measurements.</strong></p><ul><li>Achieving reliable viscosity results in routine measurements is often more challenging than expected.</li><li>Small setup errors, inappropriate geometry selection, or inconsistent sample handling can lead to major deviations in results - even when using the same instrument.</li><li>This webinar focuses on best practice in rotational viscometry, with an emphasis on daily QC and application measurements.</li><li>It will explain how to select the right measurement setup, define meaningful test parameters, and avoid the most common errors.</li><li>Using real-world examples, the webinar will demonstrate how factors such as spindle choice, shear conditions, temperature control, and sample preparation influence viscosity data.</li><li>Participants will learn how to improve repeatability, reproducibility, and operator independence in routine measurements.</li></ul><blockquote><p><strong>Presenter:</strong> Viktor Christopoulos</p><p>Viktor Christopoulos obtained his PhD in Chemistry from the Technical University of Graz, with a focus in the field of inorganic chemistry. He joined Anton Paar in June 2021 and currently works as product manager in the viscometry department.</p></blockquote></div></div>

Anton Paar: Achieving Reliable Viscosity Results in Daily Lab Work

Achieving Reliable Viscosity Results in Daily Lab Work

Find out how to choose the right setup, avoid common measurement mistakes, and improve reproducibility in your lab viscosity measurements.

<p><strong>Quality driven organizations recognize that preventing material mix-ups begins with reliable verification. Modern manufacturing environments depend on processes that can distinguish unknown alloys from known specifications with confidence – relying solely on labeling is insufficient. Consequently, Positive Material Identification (PMI) is essential for preventing mix-ups and safeguarding product quality.</strong></p><p>In this live webinar, you’ll learn exactly when to use Grade Identification / Grade Search for unknown materials, and when to rely on Grade Control / Grade Verification to confirm an expected grade quickly and confidently.</p><p>If you know what the grade should be, verification gives you the fastest, clearest answer: OK or No Match. If you don’t, identification helps you narrow down possible candidates from your grade libraries. Quality minded organizations recognize that they retain ultimate responsibility for ensuring accurate metal verification.</p><h4><strong>We’ll outline a practical approach for inspecting incoming and outgoing components:</strong></h4><ul><li>Identify unknown metals with grade search</li><li>Verify known grades with a clear match/no match result</li><li>Choose the right tool for each task</li></ul><p>We’ll demonstrate real world workflows using mobile OES for rapid alloy checks, handheld XRF for quick specification screening, and show how adding grade information enhances results even on stationary OES analyzers.</p><p>This is rounded out by a brief overview of the <strong>SPECTRO metal database</strong> – how it works and how it effectively complements the work with the spectrometer.</p><h4><strong>Why attend:</strong></h4><ul><li>Strengthen quality assurance by aligning verification steps with the right analytical method</li><li>Reduce risk by integrating fast and reliable grade verification into inspection workflows</li><li>Improve decision‑making with structured grade data and proven metal analysis tools</li></ul><h4><strong>Join us live:</strong></h4><ul><li>9:30 AM CET (Berlin); 4:30 PM SGT (Singapore) — Time Slot 1</li><li>11:00 AM EDT (New York); 4:00 PM CET (Berlin) — Time Slot 2</li></ul><blockquote><p><strong>Presenter:</strong> Lars Jenster (Product Support Specialist for the Arc/Spark product line and the handheld XRF SPECTRO xSORT)</p><p>Lars Jenster offers SPECTRO customers and service engineers worldwide support regarding questions about these instruments. Lars joined SPECTRO as a trainee in 1995 and has remained with the company ever since, during which time he also spent two and a half years working at the SPECTRO subsidiary in the United States.</p><p><strong>Presenter:</strong> Julius Kemper (Product Support Specialist for the Arc/Spark product line)</p><p>Julius Kemper supports SPECTRO customers and service technicians worldwide and assists with questions about the devices. Julius joined SPECTRO as a trainee in 2021 and has been part of the Arc/Spark Product Support Team since 2023.</p></blockquote>

SPECTRO / AMETEK: Grade Search or Grade Control: Choosing the Right Method for Reliable Metal Verification

Grade Search or Grade Control: Choosing the Right Method for Reliable Metal Verification

Join this webinar to learn practical PMI workflows, alloy grade verification strategies, and how OES and XRF improve quality assurance and metal identification.

Choosing Right Method for Reliable Metal Verification

<p><strong>In this presentation, we will introduce the Thermo Scientific Hypulse Surface Analysis System and demonstrate how it can be used to go beyond the limits of ion beam depth profiling. Our application scientists will show how the novel femtosecond laser ablation system differs from monatomic and gas cluster ion beams by maintaining chemical information during profiles and increasing the range of depth into the sample that can be analyzed. Plus, we’ll also demonstrate how the Hypulse System is a fully-featured surface analysis instrument, and how Thermo Scientific™ Avantage Software can be used to interpret the collected data.</strong></p><blockquote><p><strong>Presenter:</strong> Robin Simpson, Application Scientist </p><p>Dr. Simpson is involved in system demonstrations, customer training, and production of marketing content for surface analysis products. He joined the team in 2017 but had close links to the team for four years prior to that while he was undertaking his engineering doctorate at the University of Surrey. During this time, his thesis investigated the effects of argon cluster depth profiling on varied material surfaces using the MAGCIS ion source.</p><p><strong>Presenter:</strong> Paul Mack, Senior Application Scientist </p><p>Dr. Mack joined Thermo Fisher Scientific in 2001 as an applications scientist, with focus on Auger electron spectroscopy. Soon after joining he became responsible for developing data processing tools for interpreting angle resolved XPS spectra and he also created an algorithm for automatic analysis of XPS survey spectra. As senior applications scientist for XPS, he works in a team that helps our XPS users make the most of their surface analysis tools for materials characterization. Before joining Thermo Fisher, Paul received a master of chemistry degree from the University of Southampton, where he also later studied rotational and vibrational spectroscopy as well as quantum mechanics for his PhD.</p><p><strong>Presenter:</strong> Tim Nunney, Sr. Manager, Application Scientists &amp; Product Marketing</p><p>Dr. Nunney’s role involves all aspects of product marketing for X-ray photoelectron spectroscopy, including managing the applications team, customer evaluations, product development, training, and commercial support. He has been with Thermo Fisher Scientific since 2004, previously holding positions as an applications scientist and in operations. Prior to joining Thermo Fisher, Tim worked as a post-doctoral research fellow at the University of Southampton, investigating the dynamics of molecular dissociation on metal surfaces. He completed a PhD in surface science at the University of Liverpool, an MSc in surface science and catalysis at the University of Liverpool, and a BSc in chemistry from the University of Nottingham. </p><p><strong>Presenter:</strong> Hsiang-Han Tseng, Application Scientist </p><p>Dr. Tseng develops applications workflows for surface spectroscopic tools for sample characterization and analysis and provides customer demonstrations and training. Prior to joining Thermo Fisher, Hsiang-Han obtained her BS in chemistry from National Taiwan Normal University as well as an MRes in nanomaterials and a PhD in materials science, both from Imperial College, London, UK. During her PhD, she investigated the spectroscopic, morphological, and magnetic properties of molecular thin films based on porphyrins and phthalocyanines for organic spintronic applications. &nbsp;</p><p><strong>Presenter:</strong> Simon Bacon, Application Scientist </p><p>Dr. Bacon specializes in X-ray photoelectron spectroscopy. His primary role is training customers on highly technical XPS instrumentation and developing novel training methods. He first started working at Thermo Fisher in 2021 as a KTP associate in collaboration with the University of Surrey to develop the prototype instrument for a new XPS product line. Prior to this, Simon studied and worked in a diverse range of scientific disciplines, earning a BSc in biological science from University of Manchester, an MSc and MPhil in forensic science from University of Manchester and Brunel University, respectively, and an EngD in material science from University of Surrey. He also contributed to medical research as a research assistant at MRC and battery research as a research fellow at the Faraday Institution.&nbsp;</p></blockquote>

Thermo Fisher Scientific: Hypulse Surface Analysis System Demonstration

Hypulse Surface Analysis System Demonstration

Introduce Thermo Scientific Hypulse Surface Analysis System and demonstrate how it can be used to go beyond the limits of ion beam depth profiling.

<p><strong>Inductively Coupled Plasma Mass Spectrometry (ICP‑MS) is widely recognized for its sensitivity and multi‑element capabilities. Whether you are a novice, intermediate, or advanced user of the technique, unexpected challenges can arise. &nbsp;These challenges range from routine maintenance issues to complex matrix or spectral interferences as well as environment specific considerations. In this webinar, we will explore how the help functions and diagnostic tools embedded in MassHunter® software can be used to efficiently overcome these challenges. Attendees will gain insight into using the software as an active partner in method development and troubleshooting, as well as a resource for minimizing downtime by performing proactive maintenance tasks.</strong></p><blockquote><p><strong>Presenter:</strong> Jeff Sayen (ICP-MS Application Scientist)</p><p>Jeffrey Sayen s an ICP-MS Application Scientist at Agilent Technologies with over 15 years of experience in analytical chemistry. He specializes in atomic spectroscopy techniques, including ICP-MS, ICP-OES, and Flame AA. Jeffrey is passionate about ICP-MS and enjoys delivering product and application overviews at customer sites, seminars, and industry events. Prior to joining Agilent, he held the position of Senior Field Application Scientist at another major instrument manufacturer, where he focused on analytical methodologies across a range of regulated industries. He holds both undergraduate and graduate degrees in Inorganic Chemistry from Michigan State University.</p></blockquote>

Agilent Technologies: Atomic Spectroscopic webinars

How can MassHunter software help you when you need help with your ICP-MS?

Using MassHunter® software diagnostics to optimize ICP-MS workflows, solve interferences, and improve method development and maintenance efficiency.

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Webinars LabRulezICPMS Week 17/2026

Essential Trace Elements in Edible Plants: Balancing Nutritional Benefits and Potential Health Risks

PhD student Sabina Cerulová: Science gives you so much, but it also takes a lot — you really must enjoy it