<h3>Lunch &amp; learn tips &amp; tricks series 2026 – part 1</h3>In modern analytical laboratories, efficiency, consistency, and data confidence are essential. Whether you are operating an ICP-OES or ICP-MS system, the way you use your software can significantly influence productivity and analytical performance. In the first session of our Lunch &amp; Learn Tips &amp; Tricks Series, we focused on one of the most common themes raised by users: how to navigate <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1489">Qtegra </a>software more effectively and optimize everyday workflows.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Mastering_Qtegra_Software_Practical_Strategies_to_Improve_Your_Daily_Lab_Workflow_3d35454782.jpg" alt="Thermo Fisher Scientific: Mastering Qtegra Software: Practical Strategies to Improve Your Daily Lab Workflow" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Mastering_Qtegra_Software_Practical_Strategies_to_Improve_Your_Daily_Lab_Workflow_3d35454782.jpg 245w," sizes="100vw" width="1024" height="512">This session explored three key areas in detail: understanding the structure of Qtegra and the Configurator, using the Dashboard as your operational control center, and building smarter, more efficient LabBooks. Below is a structured recap of the key insights shared during Part 1.<h3>Understanding the structure of Qtegra</h3>One of the most valuable features of Qtegra software is its consistency across multiple instrument platforms. Whether you are working with the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products?category=227&amp;instrumentationItems=84&amp;manufacturerItems=3&amp;search=icap+pro">iCAP PRO ICP-OES</a>, the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products?category=232&amp;instrumentationItems=83&amp;manufacturerItems=3">iCAP MX ICP-MS</a>, the iCAP 7000 OES, or Qnova ICP-MS systems, the interface and workflow logic remain familiar. This consistency reduces the learning curve when transitioning between instruments and supports standardised training across laboratories.Qtegra consists of two primary components: the Qtegra application itself and the Configurator.<ul><li>The Qtegra application is where you directly interact with your instrument. It is used to create LabBooks, control the instrument, execute analyses, and review results.</li><li>The Configurator, in contrast, defines how your system behaves at a deeper level. It controls system-level settings that underpin daily operation. Within the Configurator, users can manage features such as Fast Uptake setup, drain sensor configuration, wavelength libraries for ICP-OES systems, the Reaction Database for ICP-MS systems, and user access permissions.</li></ul>Understanding the distinction between these two components helps users troubleshoot more effectively and ensures that system configuration aligns with laboratory requirements.<h3>Using the dashboard as your central hub</h3>When Qtegra is opened, the first screen presented is the Dashboard. The Dashboard functions as the central hub for instrument monitoring and control. From this location, users can view instrument status, monitor live operating parameters, access tuning tools, review performance checks, and identify error or interlock notifications.<ul><li>For ICP-OES users, the Dashboard provides access to tune sets, source settings, AutoPeak alignment, autotuning functions, and live views such as Plasma TV. These tools allow users to confirm that the plasma and optical system are performing as expected before analysis begins.</li><li>For ICP-MS users, the Instrument tab within the Dashboard provides access to autotune routines, performance report summaries, gas flow settings, nebuliser adjustments, operating mode selection such as Standard, KED, or CCT modes, IntelliLens control, and real-time data streams.</li></ul>The Dashboard should be used as a structured checkpoint before running any analysis. Confirming that all parameters are within acceptable ranges reduces the likelihood of interruptions and supports consistent performance throughout the run.<h3>The get ready workflow: structured instrument preparation</h3><ul><li>The Get Ready function, which is launched directly from the Dashboard, provides a guided preparation workflow. This feature is designed to ensure that the instrument is fully configured and operating correctly for the selected method before analysis begins.</li><li>Within Get Ready, users can access scheduling tools that automate warmups, standby routines, shutdowns, and maintenance checks. These tools are particularly beneficial for laboratories operating multiple shifts or managing variable workloads.</li></ul>For ICP-MS systems, the Get Ready workflow includes automated performance checks, autotune routines, and controlled warm-up conditions. These routines verify that the instrument is operating within its expected performance range.By following the structured steps within Get Ready, laboratories can reduce the risk of missed preparation tasks and maintain day-to-day analytical consistency.<h3>Building smarter LabBooks</h3>The LabBook forms the foundation of every analytical sequence in Qtegra. A carefully constructed LabBook improves efficiency, reduces setup errors, and simplifies data review.Users can create a LabBook from scratch or begin with a template. Templates are particularly useful for laboratories that integrate with LIMS systems or import sample lists via CSV files, as they promote standardisation and consistency.<h4>Defining analytes</h4><ul><li>For ICP-OES methods, users must select appropriate wavelengths and evaluate potential spectral interferences.&nbsp;</li><li>For ICP-MS methods, users select the required masses, consider isobaric and polyatomic interferences, and use the Reaction Database to support reaction mode selection.</li></ul>Careful analyte selection at this stage helps prevent complications later in the analytical workflow.<h4>Configuring acquisition parameters</h4>Acquisition parameters define how the instrument collects data.<ul><li>For ICP-OES systems, this includes selecting viewing modes, choosing wavelength ranges such as iFR or eUV, and defining integration times.</li><li>For ICP-MS systems, this includes selecting operating modes such as Standard, KED, or CCT, configuring Reaction Finder options, enabling Intelligent Matrix Handling, and defining digital trigger settings.</li></ul>Thoughtful parameter configuration ensures that data quality objectives are met without unnecessary reanalysis.<h4>Using intelligent uptake and rinse</h4>The Intelligent Uptake and Rinse feature detects when the sample or rinse solution reaches the nebuliser. This ensures consistent timing across samples and improves overall throughput. In high-throughput environments, this feature contributes to both efficiency and reproducibility.<h4>Calibration and quantification strategy</h4>Calibration design is central to reliable quantification. Qtegra allows users to manage global standards, configure dilution tools, select calibration fit types, assign internal standards, and establish quality control samples.For ICP-OES systems, users can define standard ranges and switch points. For SemiQuant workflows, Relative Sensitivity Factors can be applied.Establishing these parameters during LabBook creation ensures that data validation is straightforward once analysis is complete.<h4>Autosampler and sample list setup</h4>For laboratories using the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1715">iSC-65 autosampler</a>, features such as StepAhead, custom rack definitions, colour-coded sample views, and visual integrity checks support efficient sequence management.When constructing the sample list, users should clearly define sample types, establish a logical sequence order, and configure column layouts appropriately. Setting flags and limits during initial setup simplifies the data review process and supports quality assurance.<h3>Why workflow optimisation matters</h3>Optimising Qtegra usage does not require learning new software features. Instead, it involves using existing tools more strategically. By treating the Dashboard as a pre-run checkpoint, using Get Ready consistently, and constructing LabBooks with long-term efficiency in mind, laboratories can reduce downtime, improve reproducibility, and strengthen confidence in analytical results.<h3>Looking ahead to part 2</h3><blockquote>In Part 2 of the Qtegra Tips &amp; Tricks series, we will focus on post-analysis best practices. Topics will include interpreting signal intensities, reviewing calibration performance, evaluating recoveries and readbacks, applying flags effectively, exporting data, and implementing practical workflow improvements discussed in Part 1.</blockquote>By building a structured approach to both preparation and data review, laboratories can transform routine analysis into a streamlined, reliable, and repeatable process.We look forward to continuing the discussion in Part 2.<h5>Acknowledgement</h5>I would like to thank Matthew Gregory Field Applications Scientist, North EMEA, Trace Elemental Analysis and David Fishwick Field Applications Scientist, North EMEA, Trace Elemental Analysis for the support on this blog and the webinars<h4>Sign up for our webinars live and on demand.</h4>English<ul><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/5795">Lunch and Learn Tips and Tricks Series: Qtegra Part 1</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/5976">Lunch and Learn Tips and Tricks Series: Qtegra Part 2</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/5977">Lunch and Learn Tips and Tricks Series: Trace Elemental Analysis (ICP-OES &amp; ICP-MS)</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/5978">Trace Elemental Analysis: Ask the Expert</a></li></ul>Deutsch<ul><li>19. März 2026 <a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/wcc/r/5179134/393E071E3B501943730958BA6203F477">Interne Standards in der ICP-OES: Ein Praxisguide für zuverlässige Qualitätssicherung im Labor</a></li><li>18. Juni 2026 <a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/wcc/r/5179292/AE4C576B6A54D1AC182F7F77573D380F">Fehler reduzieren, Durchsatz steigern: Autoverdünnung mit PrepFast am ICP-MS</a></li><li>17. September 2026 <a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/wcc/r/5179423/B5019C560431BADCA2A76E54E4EFE56F">ICP-OES smarter nutzen: Probendurchsatz erhöhen, Ressourcen sparen</a></li><li>17. Dezember 2026 <a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/wcc/r/5179530/94EEDD1F56138F5EEE2AF24E29E6C12A">Qtegra ISDS Software Unlocked – Live im Expertengespräch</a></li></ul>Visit us on&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/">LinkedIn:</a>&nbsp;#Qtegra, #ICPMS, #ICPOES, #TraceElementalAnalysis<blockquote><h5>Petra Gerhards</h5>Petra Gerhards, Dipl-Ing, is Regional Marketing Manager of GC and GC-MS for EMEA at Thermo Fisher Scientific. She has more than 29 years of experience in the fields of GC-MS, SPE and LC-MS. Since joining the regional team she has contributed to workflow solutions combining vials and closures with SPE solutions, GC-MS and LC-MS. She works with KOL's on data for regional specific marketing campaigns, organizes in-house seminars and works on customer specific solutions. Her main expertise is in the field of doping and drugs-of-abuse analysis.</blockquote>

Mastering Qtegra Software: Practical Strategies to Improve Your Daily Lab Workflow

Since the beginning of this year, a project to develop a light-based electron microscope, LightEM, has been underway at CEITEC Brno University of Technology (BUT). The principal investigator is Andrea Konečná from CEITEC BUT and the Faculty of Mechanical Engineering BUT, who has secured support for the project through the prestigious ERC CZ program. Over the next five years, her research team aims to develop and test a light-based electron microscope. This technology would allow scientists to adaptively modulate the electron beam during experiments or observe processes over time – capabilities that are not possible with conventional electron microscopes.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_VUT_Vaclav_Konicek_Mikroskop_budoucnosti_Spojeni_svetla_a_elektronu_ziskalo_prestizni_grant_4_2062655721.jpeg" alt="CEITEC/Václav Koníček: Microscope of the Future: Combining Light and Electrons Wins Prestigious Grant: Andrea Konečná's group" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_VUT_Vaclav_Konicek_Mikroskop_budoucnosti_Spojeni_svetla_a_elektronu_ziskalo_prestizni_grant_4_2062655721.jpeg 235w," sizes="100vw" width="1600" height="1067">Over the coming five years, Andrea's team will work on improving existing electron microscopes. Her project, Light-Based Electron Microscope (LightEM), focuses on the interaction between electrons and light and could help overcome some of the limitations of classical electron microscopy. “We are trying to improve the electron beam. What we want to do is, figuratively speaking, shoot an intense laser beam into the microscope and influence electrons using light. Simply put, we aim to create adjustable ‘glasses’ for the electron microscope using light and change how optics is traditionally done in electron microscopy,” explained Andrea.According to her, this approach should bring higher resolution, new imaging techniques, and the ability to study dynamic processes. “With light, the resolution should be even better. Moreover, we could image sensitive samples, which is usually problematic. We could also observe processes over time –&nbsp;stimulate a sample with light, for example by heating it, and then dynamically monitor what is happening,” she added.<h3>The microscope will offer better resolution and new imaging techniques</h3>Andrea points out that standard electron microscopes use magnetic lenses to image and focus electrons onto a sample, but these lenses have imperfections that limit resolution. The best electron microscopes in the world therefore use many lenses – similar to professional camera lenses – to compensate for these defects and achieve atomic resolution. A light-based electron microscope could change this.“We would like to demonstrate that such complex lens systems –&nbsp;whose production, alignment, and operation are very expensive and demanding –&nbsp;could be replaced by a specially modulated laser beam. Compared to conventional lenses, a laser beam can be used not only for magnification, reduction, or aberration correction, but also offers great flexibility and the possibility to create new ‘exotic’ types of electron beams. Electrons don’t have to be focused only into a point; we can create a beam shaped like a ‘donut.’ In addition, the beams could be modulated quickly and adaptively,” said Andrea.According to her, such a modified microscope could be used in many fields. “Thanks to the possibility of light-based modulation of the electron beam during experiments, we could more efficiently image sensitive samples, which is crucial for biology. Or we could detect defects in materials and semiconductor components more quickly,” she added.This is highly unique research with no equivalent in scope, either in the Czech Republic or abroad. According to Andrea, only a few studies on the topic have been published so far. “At the time I was writing the grant, only a few theoretical and experimental papers had demonstrated the basic concept –&nbsp;that electrons can be focused or otherwise modulated using a laser beam. But they did not go as far as we would like, namely to create a prototype microscope where part of the standard electron optics is replaced by a laser beam,” she said.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_VUT_Vaclav_Konicek_Mikroskop_budoucnosti_Spojeni_svetla_a_elektronu_ziskalo_prestizni_grant_3_1ec4c49bf5.jpeg" alt="CEITEC/Václav Koníček: Microscope of the Future: Combining Light and Electrons Wins Prestigious Grant: Andrea Konečná's research" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_VUT_Vaclav_Konicek_Mikroskop_budoucnosti_Spojeni_svetla_a_elektronu_ziskalo_prestizni_grant_3_1ec4c49bf5.jpeg 235w," sizes="100vw" width="1600" height="1067"><h3>Unique research supported by the Ministry of Education</h3>The project’s strong potential is confirmed by the fact that Andrea Konečná received an ERC CZ grant from the Czech Ministry of Education, Youth and Sports. The program aims to support researchers who applied for a European ERC grant, succeeded in evaluation, but were not funded due to limited resources.“There is enormous competition within the European ERC program. I submitted this project twice and both times advanced to the second round, where I presented it and discussed it with the panel. Each time I received an A rating, but unfortunately without funding. The Ministry looks at these European evaluations and ultimately supported my project. To be honest, it is mainly about prestige, because otherwise the conditions are the same. The project still runs for five years, and the Ministry supported it in full, so we receive the same funding we would have received from the European Union,” Andrea noted.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_VUT_Vaclav_Konicek_Mikroskop_budoucnosti_Spojeni_svetla_a_elektronu_ziskalo_prestizni_grant_2_3114b2e414.jpeg" alt="CEITEC/Václav Koníček: Microscope of the Future: Combining Light and Electrons Wins Prestigious Grant: Andrea Konečná's research" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_VUT_Vaclav_Konicek_Mikroskop_budoucnosti_Spojeni_svetla_a_elektronu_ziskalo_prestizni_grant_2_3114b2e414.jpeg 235w," sizes="100vw" width="1600" height="1067"><h3>Two prestigious grants – and motherhood alongside</h3>A few years ago, Andrea Konečná also received the prestigious JUNIOR STAR grant from the Czech Science Foundation, which supports outstanding early-career researchers. She is currently the principal investigator of two major projects, while also balancing motherhood since last year.“Maybe it’s still too early to evaluate, because my daughter is still small and I was on maternity leave for some time. But honestly, it is demanding. At the same time, the flexibility of our work makes it easier than in other professions. Moreover, the JUNIOR STAR project is already in its fourth year, and several excellent PhD and master’s students have joined during that time, so many smaller projects were able to continue even during my maternity leave. I’m also happy that several of these colleagues will now join the ERC CZ project,” she concluded.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_VUT_Vaclav_Konicek_Mikroskop_budoucnosti_Spojeni_svetla_a_elektronu_ziskalo_prestizni_grant_1_8369f441d5.jpeg" alt="CEITEC/Václav Koníček: Microscope of the Future: Combining Light and Electrons Wins Prestigious Grant: Andrea Konečná" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_VUT_Vaclav_Konicek_Mikroskop_budoucnosti_Spojeni_svetla_a_elektronu_ziskalo_prestizni_grant_1_8369f441d5.jpeg 235w," sizes="100vw" width="1600" height="1067"><h3>A major success for CEITEC Brno University of Technology</h3>“I greatly appreciate the success of Andrea Konečná, who managed to succeed in a highly competitive environment. It is the result of long-term high-quality scientific work and significant personal dedication. At the same time, I am pleased that at BUT, we are systematically creating conditions to support excellent research. One of the key tools is the Research Excellence Support Fund, through which we motivate and support researchers in preparing applications for prestigious grants such as ERC, EXPRO, JUNIOR STAR, or MSCA. These are precisely the types of projects that push the boundaries of knowledge and strengthen the international standing of our university,” said Martin Weiter, Vice-Rector of BUT for Research and Knowledge Transfer.

Microscope of the Future: Combining Light and Electrons Wins Prestigious Grant

Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 30th March 2026? Check out new documents from the field of spectroscopy/spectrometry and related techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">LabRulezGCMS</a> libraries.</blockquote>This week we bring you application notes by Metrohm, Shimadzu, Thermo Fisher Scientific and Waters Corporation!<h3>1. Metrohm: Quantification of methanol in contaminated spirits</h3>Protecting consumers from contaminated beverages<ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_rs_056_download_3b37cb883a.pdf">Full PDF for download</a></li></ul>An alarming global trend highlights the serious harm that can result from ingesting illegal, improperly distilled alcohol. Home-distilled spirits prepared using industrial solvents (i.e., wood alcohol) and presented as legitimate alcoholic beverages often contain methanol. Methanol causes blindness and can lead to death when ingested. This has led to fatal consequences around the world [1–3].&nbsp;The breaking point for the Czech Republic came in September 2012. The sale of hard liquor was temporarily banned after 20 people died from the consumption of spirits with dangerous levels of methanol [2]. After an exhaustive study using various screening tools, the Czech Republic adopted Raman spectroscopy as the method of choice for identifying and quantifying methanol in contaminated spirits. This Application Note demonstrates how Raman spectroscopy can be employed as an efficient and rapid screening method for samples of rum contaminated with methanol.<h4>EXPERIMENT&nbsp;</h4>This example study measures commercially available coconut rum that is spiked with methanol in concentrations between 0.33% and 5.36%. The <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=220&amp;search=iRaman">iRaman NxG 785H</a> with a fiber-optic probe is used to collect Raman spectra of the mixtures (Figure 3). Table 1 lists the relevant equipment and instrument settings used for this application study. The peak at around 1000 cm-1 (highlighted by the inlay of Figure 3) visibly increases with increasing concentration of methanol, becoming significant at approximately 1%.<h4>CONCLUSION</h4>These results validate that Raman spectroscopy can be used for rapid, quantitative screening of dangerous adulterants in alcoholic beverages. This technique can be expanded to investigate adulteration in other media such as food, petroleum, and pharmaceutical drugs [4].<h3>2. Shimadzu: Evaluation of Organic Impurities in Lithium Carbonate by TOC Analysis</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_01098_en_ec9b3e73fc.pdf">Full PDF for download</a></li></ul><h4>User Benefits</h4><ul><li>TOC analysis enables effective control of organic impurities in lithium carbonate.</li><li>Using the combustion tube kit for high-salt samples can extend the lifespan of the combustion tube and catalyst, reducing maintenance frequency.</li><li>With the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=1&amp;search=ASI-L+autosampler">ASI-L autosampler</a>, multiple samples can be measured automatically, improving throughput and efficiency</li></ul>Lithium carbonate (Li2CO3) is an important material used in a wide range of applications in the lithium-ion battery industry. For example, it is used as a lithium source for cathode active material synthesis and electrolyte salt production, as a raw material for oxide-based solid electrolytes, and as a form of lithium commonly recovered in recycling processes.&nbsp;Because impurities in lithium carbonate can affect downstream processes and final products, appropriate control is essential. In particular, organic impurities require especially careful attention because they may originate from so many sources, such as solvents and processing aids used during purification, residual organics from manufacturing steps, or contamination introduced during handling and storage.&nbsp;Total organic carbon (TOC) analysis offers an effective way to manage such organic impurities in raw materials. This article presents an example of using a <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=1&amp;search=TOC-L">Shimadzu TOC-L</a> total organic carbon analyzer (Fig. 1) to evaluate the TOC content of lithium carbonate.<h4>TOC Analysis&nbsp;</h4><h5>TOC Analysis Methods&nbsp;</h5>Two commonly used methods are available for TOC analysis:&nbsp;(1) TC - IC method: Total carbon (TC) and inorganic carbon (IC) are measured separately, and then TOC is calculated as the difference (TOC = TC – IC).(2) NPOC method: TOC is measured as non-purgeable organic carbon (NPOC). After acidifying the sample to pH &lt; 3, IC is subsequently removed by sparging and the remaining carbon is measured as TC, which is regarded as TOC. The acidification and sparging steps are performed automatically by the instrument.&nbsp;For lithium carbonate solutions, the amount of carbonatederived IC is typically very high. As a result, the TC–IC method tends to yield calculated TOC values with a larger relative error. Therefore, the NPOC method isrecommended.&nbsp;In lithium carbonate solutions prepared as described above, IC is expected to be present mainly as bicarbonate (HCO3 –) and carbonic acid (H2CO3). If IC is not fully removed during NPOC pretreatment, the TOC result may be overestimated. Therefore, thorough IC removal is critical for samples with high IC content. For actual samples, sparging parameters, such as sparge gas flow rate and sparge time settings, can be adjusted.&nbsp;<h5>Combustion Tube for High-Salt Samples&nbsp;</h5>The prepared lithium carbonate solution contains a large amount of salts. When a large number of salt-containing samples are analyzed, salts may accumulate inside the combustion tube, which can lead to catalyst clogging, reduced sensitivity, and poorer repeatability.For this analysis, the optional combustion tube for high-salt samples was used, shown in Fig. 2. The high-salt combustion tube has a larger diameter than the standard combustion tube and contains larger catalyst particles to help mitigate saltrelated clogging. Thus, the frequency of combustion tube replacement can be significantly reduced.<h4>Conclusion&nbsp;</h4>In this article, TOC analysis was performed for a 10 g/L lithium carbonate solution using a Shimadzu TOC-L total organic carbon analyzer. By measuring TOC in the prepared solution, the TOC content in the lithium carbonate solid was calculated. The results showed good recovery rates in the spike-recovery test and consistent performance was also confirmed during long-term continuous analysis. These findings demonstrate that the TOC-L is a reliable solution for measuring TOC in lithium carbonate and for effective management of organic impurities.&nbsp;When applying the NPOC method to lithium salt-containing solutions, careful selection of the acid is essential because salts formed during acidification can affect both data quality and instrument condition. For this example, sulfuric acid is recommended.In addition, using the optional combustion tube kit for high-salt samples can extend the lifespan of the combustion tube and catalyst, thereby reducing maintenance frequency. This option is especially helpful for samples with high salt concentrations.&nbsp;In addition to lithium carbonate, the TOC-L can also be applied to TOC analysis of lithium hydroxide solutions, determination of water-extractable TOC in recycled black mass, and analytical needs in lithium refining processes based on direct lithium extraction (DLE). With its broad applicability across various upstream materials, recycling streams, and refining processes, the TOC-L supports both quality control and process optimization operations throughout the lithium-ion battery value chain.<h3>3. Thermo Fisher Scientific: Evaluating Silicon using Raman Microscopy</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/vib_silicon_analysis_with_raman_microscope_app_note_mcs_an1232_en_11_2024_1887815_web_50639c9148.pdf">Full PDF for download</a></li></ul>Raman spectroscopy is a form of vibrational spectroscopy that probes chemical bonds and molecular structure and is sensitive to small changes in chemical and structural environments. The Raman spectrum of a material is a molecular “fingerprint” that can be used for identification of unknown materials and for characterizing and qualifying expected materials. Since intermolecular effects and lattice vibrations are also detected, it can be used to evaluate crystallinity. Mechanical phenomena such as strain can also be detected from peak shifts in Raman spectra. Raman imaging allows visualization of the distribution of components or changes in physical state across the sample.<h4>Silicon in aluminum&nbsp;</h4>Silicon is used in alloys with aluminum to increase the strength of lightweight aluminum-based parts. Addition of silicon to aluminum also alters the viscosity of melted aluminum, improving the castability. These alloys typically contain 3% to 25% silicon. While silicon and aluminum can form a eutectic mixture, it is common to have finely dispersed silicon particles throughout the material.¹ The size and distribution of silicon particles can affect the strength of the aluminum.&nbsp;One common example of an aluminum product, aluminum foil, is made up of almost pure aluminum (approximately 98.5%) but it does contain small amounts of silicon and iron.² Raman imaging of a piece of aluminum foil reveals small particles of silicon (Figure 1). A <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2237">Thermo Scientific™ DXR3xi Raman Imaging Microscope </a>was used with a 532 nm laser and a 100X&nbsp;metallurgical objective to collect the Raman imaging data. An area of 408 μm x 208 μm was imaged using an image pixel size of 1 μm. The Raman image, based on the 520 cm-1 peak of silicon, shows the spatial distribution of the particles and image analysis provides size and shape information. In this case, 81&nbsp;silicon particles were identified with a size (area) range of 6-151 μm². This analytical approach may be extrapolated to other types of Si/Al alloy parts.<h4>Conclusion&nbsp;</h4>The importance of silicon as a technologically significant material cannot be overstated. It has properties that make it useful in numerous different types of products. Raman micro-spectroscopy has proven itself an important tool for the assessment of molecular structure and physical states of silicon. Raman images provide a way to observe the spatial distribution of silicon and silicon-containing components, structural variations such as crystallinity, and physical effects such as strain. This note showed a few representative examples to illustrate some of the advantages offered by Raman microscopic analysis of silicon. The coverage is not intended to be comprehensive as there are numerous other areas where the Raman analysis of silicon is currently employed and other opportunities where it could be used. The Thermo Scientific DXR3 Raman Microscope and the Thermo Scientific DXR3xi Raman Imaging Microscope have both been shown to be excellent choices for the Raman analysis of silicon samples.<h3>4. Waters Corporation: High-Throughput Detection of Degraded Polysorbate in Biological Formulations with FMM</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/720009114_en_99c7483d1a.pdf">Full PDF for download</a></li></ul>The FDA requires that all biologic formulations be free of visible particles and has defined allowable levels of subvisible particles (SVPs) larger than 10 µm to ensure the potency, efficiency, and safety of these drug.1 While most protein drug particle analysis focuses on particles formed due to formulation instability, SVPs formed through the degradation of formulation excipients must also be considered.&nbsp;Polysorbates 20 (PS20) and 80 (PS80), best known as Tween-20 and -80, are excipients used in &gt;70% of marketed parenteral biological drugs to improve product stability and shelf life.2 However, when these formulations are stored for long periods of time (&gt;6 months) at low temperatures (4 °C), visible and subvisible particles are formed due to the enzymatic hydrolysis of the polysorbates by host cell proteins (HCPs) such as esterases and lipases.3,4 PS20 in particular has been found to be extremely prone to degrading into fatty acid particles.5 Lauric, myristic and palmitic acids are the most common fatty acid degradation products, and there is a direct correlation between low fatty acid solubility and particle formation in common formulation buffers.3–7 However, high-throughput, sensitive, and specific analysis of polysorbate particles has been difficult due to their complex chemistry and their low concentrations (&lt;&lt;0.5%) in high protein concentration (&gt;100–200 mg/mL) formulation environments, making it a perennial needle in a haystack problem.In this application note, we introduce the Aura™ polysorbate degradation assay, a specific and quantitative assay that detects free fatty acid particles (FFAs) formed during polysorbate degradation on Aura PTx System. The assay analyzes 96 samples using anywhere from 5 µL–10 mL of sample in a few hours. <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2190">Aura™ Systems</a> use backgrounded membrane imaging (BMI) and fluorescence membrane microscopy (FMM) to count, size and ID particles from 1 µm to 5 mm. Fluorescent labels utilized by FMM are selected based on thier ability to interact with particles of a certain nature, allowing for the generation of key information related to identity of the particles.<h4>Results and Discussion&nbsp;</h4><h5>Morphological Appearance of Different Fatty Acid Particles&nbsp;</h5>Aura systems image every particle, enables subvisible particle size distributions analysis, and makes morphological differentiation possible using built-in image analysis filters. When we analyze different free fatty acid solutions with Aura PTx System, we find that each forms particles with different morphological characteristics. Lauric acid particles are large and irregular clusters, myristic acid particles are small and oval shaped, and palmitic acid particles form fibril-like particles and small circular clusters (Figure 2a-c). These unique morphological characteristics suggest the presence of free fatty acid particles that can then be confirmed with FMM using labeled fluorescence.<h4>Conclusion&nbsp;</h4>Aura PTx System and <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2190">Aura+ System</a> can easily detect the major degradation components of PS20 in proteincontaining samples at any stage of the drug manufacturing process. The method only requires 5 µL of sample, is specific and sensitive, and can analyze 96 samples in just a few hours, far outperforming other techniques. Aura PTx System and Aura+ System can also identify and differentiate the key degraded particulates from polysorbate formulation by their distinguishable shape, appearance, and specific labeling with BODIPY FL C16. The Aura polysorbate assay can detect FFAs at concentrations relative to lauric acid above 9.38 µM (&gt;2183 counts/mL) and quantitate above 18.75 µM (&gt;2976 counts/mL).

News from LabRulezICPMS Library - Week 14, 2026

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While many Semiconductor applications call for ppt levels and ICPMS analysis, there are many applications in this market that can utilize and ICP-OES for the analysis.Matrices mainly include high silicon levels or looking for traces in a variety of reagents, both inorganic and organic. This master class will look at handling high silicon as well as inorganic reagents like H2O2, HNO3, H2SO4, H3PO4…. ICP is well suited for organic reagent analysis as well. This presentation will also include organic solvent setup and optimization.<blockquote>Presenter: Paul Krampitz (Application Scientist, Agilent Technologies, Inc.)Paul is a graduate of Bowling Green State University with a Chemistry Bachelor of Science degree. Twenty – five years of Spectroscopy experience mainly Inductively Coupled Plasma (ICP) Spectroscopy as well as ICP-MS and AAS. His experience also includes X-Ray Fluorescence (ED, WD), Laser Ablation, Inorganic Speciation and Microwave Plasma Spectroscopy. Market Segment expertise includes environmental, petrochemical, metallurgical applications.Presenter: Sima Singha, PhD (ICP-OES Application Scientist, Atomic Spectroscopy, Agilent Technologies, Inc.)Sima has over fifteen years of hands on experience as an applications scientist in the field of atomic spectroscopy. Before joining Agilent in 2017, managed an agricultural chemistry laboratory for the analysis of water, soil, and plant tissue digests using ICP-OES for various EPA methods. She received a Ph.D. degree in Chemistry from the University of Illinois at Chicago with numerous peer-reviewed publications.</blockquote>

Agilent Technologies: Semiconductor Applications and Setup for a variety of Solvents and Matrices by ICP-OES

Semiconductor Applications and Setup for a variety of Solvents and Matrices by ICP-OES

Learn how ICP-OES enables semiconductor analysis of silicon-rich samples and reagents, offering robust trace detection and optimized solvent workflows.

Semiconductor Applications and Setup for variety of Solvents

As the needs of the semiconductor industry call for being able to measure metals at lower and lower concentrations, it is necessary to employ the best tune conditions for each of the metals of interest.This means that multiple tune modes such as cool plasma, hot plasma, oxygen, ammonia, etc. are required when analyzing a full suite of elements thus necessitating the changing of RF power, positioning of the torch and gas flows within a single analysis. &nbsp;Not only is it important to demonstrate the ability to achieve low detection limits within these methods but also to demonstrate long term stability as the instrument cycles back and forth through the various tune conditions from sample to sample.We will show examples of this with TMAH and UPW matrices.<blockquote>Presenter: Bert Woods (Application Scientist, Agilent Technologies, Inc.)Joined the Agilent ICP-MS team in 2004, with previous employment in the semiconductor industry with Dominion Semiconductor (IBM/Toshiba) and Micron. Bert is a 1997 Chemistry graduate of Radford University in Virginia and an avid Washington DC Sports fan.</blockquote>

Agilent: Agilent Webinar Series - Semiconductor and Specialty Chemical Industry

Novel Advancements in Trace Level Determination and Longterm Stability of Metals in TMAH and UPW matrices

Trace Determination and Stability of Metals in TMAH and UPW

<div>The Compact-Q DEER Spectrometer is designed to support researchers in academia and industry to efficiently characterize quantum materials, develop devices for quantum sensing, advance and validate algorithms to control qubits, and other applications in spin-based quantum technologies. The Compact-Q DEER system features a modern microwave architecture, high-resolution AWG, and digital signal processing schemes enabling high flexibility in addressing modern challenges of quantum technologies.The focus of this webinar will be to highlight the capabilities of the Compact-Q DEER spectrometer towards the characterization and coherent control of qubits for quantum technologies. Modern experiments in Quantum Information Science (QIS) demand a state-of-the-art microwave architecture, fast, high-memory, high-resolution AWGs, large transmission and detection bandwidths, and modern digital signal processing features to create the most sophisticated pulse shapes, quantum gates and read-out sequences. Having all of those features incorporated, as well as operating at an intermediate frequency of 500 MHz, and utilizing a cryogen-free 1.5 T magnet with integrated Variable Temperature Insert (iVTI) enabling temperatures from 2 K to RT, the Compact-Q system meets modern demands and provides a versatile and high-fidelity platform for probing qubit properties and execution of quantum algorithms driving innovations in quantum technologies.<h4>What to Expect</h4>During this webinar, we will demonstrate how the Compact-Q DEER is ideally suited for applications in QIS. We will show how broad-band echo sequences can be used to manipulate spin states and how electron spin coherences can be created and detected. We will explain the different spectrometer features, the data acquisition platform along with different experiments, highlighting how the Compact-Q can elevate your research in quantum information science (QIS).<h4>Key Learning Points</h4>Versatility, high-performance, and user-friendly operation of the Compact-Q DEER spectrometer will be highlighted along with:<ul><li>Easy to use resonator bandwidth control</li><li>AWG generated pulses, digital down conversion, and FIR filtering</li><li>Pulse shaping and quantum gate optimization</li><li>Broadband and selective inversion pulse schemes</li><li>Studying spin dephasing mechanisms and materials characterization</li></ul><h4>Who should attend?</h4><ul><li>Undergraduate and graduate students in chemistry, physics, quantum information science, material science, and related fields&nbsp;</li><li>Early-career researchers, postdoctoral fellows, and instrument facility managers familiar or new to EPR spectroscopy&nbsp;</li><li>Professors and instructors teaching EPR spectroscopy or related courses&nbsp;</li><li>Spectroscopy facility managers</li><li>Industry professionals, scientists, and engineers in materials science and quantum technologies industries</li></ul><blockquote>Presenter: Alvaro Montoya (Ph.D. in chemistry from the University of Florida, EPR Application Scientist, Bruker BioSpin)Alvaro Montoya began his EPR career as a Ph.D. student at the University of Florida after obtaining his B.S. in Chemistry from Susquehanna University. Early in his graduate career, he made use of CW and High Field EPR in studying the catalytic mechanisms of metalloenzymes. He then grew a profound appreciation for FT EPR and expanded his EPR toolbox for his research endeavors. After completing his Ph.D., Alvaro joined Bruker in January of 2023 working as an Applications Scientist.Presenter: Dmitry Akhmetzyanov (Ph.D. in chemistry from Goethe University Frankfurt am Main, Research Scientist, Bruker BioSpin)Dr. Akhmetzyanov began exploring EPR spectroscopy during his undergraduate studies at Kazan University, the birthplace of EPR. Throughout his Bachelor’s and Master’s programs, Dmitry’s work centered on applying EPR techniques to materials science. For his Ph.D., Dmitry joined Thomas Prisner’s group at Goethe University Frankfurt am Main, where he focused on development and applications of pulsed EPR dipolar spectroscopy to study structures and dynamics of macromolecules. After his research positions in Germany and Canada, Dmitry joined Bruker in 2024. In the current role as a Research Scientist, he focuses on advancing EPR spectroscopy, developing novel applications, and supporting customers.&nbsp;</blockquote></div>

Bruker: Meet Compact-Q DEER Spectrometer, Your Gateway to Quantum Innovation

Meet Compact-Q DEER Spectrometer, Your Gateway to Quantum Innovation

Webinar on Compact-Q DEER spectrometer for quantum information science, showcasing qubit control, pulse shaping, broadband EPR, and advanced DSP capabilities.

Compact-Q DEER Spectrometer, Gateway to Quantum Innovation

<div><div id="inner_content_body_text" data-content-id="394785">Join us for an exclusive live webinar introducing the new Litesizer DIF series of laser diffraction particle size analyzers. Designed for both liquid and dry dispersions, the Litesizer DIF delivers precise and reproducible particle size distributions across the nanometer to millimeter range.Learn how its best-in-class optical setup, Quick-Click dispersion units, and Kalliope software enable seamless, high-confidence measurements – whether for R&amp;D or quality control. Our experts will demonstrate how the system simplifies workflows, enhances repeatability, and minimizes manual effort to make advanced particle sizing accessible to every laboratory.&nbsp;Join the free webinar with certification of attendance now.<h5>Attend This Webinar to Learn:</h5><ul><li>How Litesizer DIF laser diffraction technology enables full-range particle size analysis</li><li>How integrated dynamic image analysis module supports method development and troubleshooting, and helps interpret and validate results</li><li>Practical strategies for the use of dispersion methods &nbsp;(wet and dry measurements)</li><li>How Litesizer DIF’s Kalliope software supports workflow efficiency</li><li>Techniques to improve QC efficiency and reduce measurement variability</li><li>Real-world application examples from industrial and research environments</li></ul><h5>Ideal For:</h5><ul><li>Scientists, lab managers, and quality professionals in the fields of building materials, minerals, paints and coatings, batteries, and environmental analysis who are seeking to modernize their particle-sizing workflow with robust, flexible technology.</li></ul><blockquote>Presenter: Dr. Aleksandra Mitrovic (Product Manager, Anton Paar GmbH, Graz / Austria)Dr. Aleksandra Mitrovic holds a degree in biochemistry from the University of Sciences in Novi Sad, Serbia. She earned her PhD in molecular biotechnology from Graz University of Technology before going on to work in applied biocatalysis across various industrial projects. In 2017, Aleksandra joined Anton Paar as a global product manager for laser diffraction, where she has accumulated eight years of experience and continues to deepen her expertise in this specialized field.</blockquote></div></div>

Anton Paar: From First to Best: Introducing the Litesizer DIF Series

From First to Best: Introducing the Litesizer DIF Series

Join us for a webinar introducing the new Litesizer DIF series of laser diffraction particle size analyzers. 

<div><div id="inner_content_body_text" data-content-id="394785">Rotational and transient viscosity measurements on a rotational rheometer provide a powerful suite of characterization tools for the flow behavior of polymer melts. From research to quality control, viscosity is a key parameter when developing polymers and their processing techniques.This webinar focuses on the application of rotational and transient viscosity measurements to polymer melts, including the instrumentation and accessories, measurement techniques, and data interpretation or analysis.<blockquote>Presenter: PhD Kiana ShirzadKiana Shirzad is an Application Scientist for Rheology and Extrusion at Anton Paar. She earned her PhD in Materials Science and Engineering from the University of California, Merced, where she focused on polymers and advanced material characterization methods. Her expertise lies in applying rheological techniques to understand complex material behavior and supporting customers in their research and industrial applications.</blockquote></div></div>

Anton Paar: Polymer Rheology: Rotational and Transient Measurements On A Polymer Melt

Polymer Rheology: Rotational and Transient Measurements On A Polymer Melt

Rotational and transient viscosity of polymer melts: rheometer techniques, instrumentation, accessories, and data interpretation for R&D and quality control.

Rotational and Transient Measurements On Polymer Melt

In this webinar, we will be looking at and defining hardware features essential for strong ICPMS performance, present integrated workflow solutions, and go over new developments in ICPMS MassHunter software.<blockquote>Presenter: Bastian Georg (Atomic Spectroscopy Application Scientist, Agilent Technologies, Inc.)He has been an Atomic Spectroscopy (ICP-MS) Application Scientist with Agilent since June 2018. Bastian holds a MSc degree in Geology from the University of Munster, Germany, and a Dr. of Science degree in Geochemistry from ETH Zurich in Switzerland. After completing a 3-yr Postdoctoral Research term at the Earth Science Department at Oxford University, Bastian joined the Trent University Water Quality Centre, Peterborough, Canada, in 2010 as senior ICP-MS research scientist. Bastian’s research record of numerous peer-reviewed publications has been cited over 3000 times, and comprises research in environmental geochemistry, cosmochemistry, isotope geochemistry and trace-metal analyses</blockquote>

Agilent Technologies: Get the Most Out of Your Flame Atomic Absorption Analysis

Fundamentals of Atomic Spectroscopy: ICP-MS

In this webinar, we will be looking at and defining hardware features essential for strong ICPMS performance.

Environmental laboratories face increasing pressure to process complex matrices for both inorganic and organic contaminants with higher efficiency, lower cost, and full regulatory compliance. This four-part webinar series provides a comprehensive overview of modern sample preparation solutions for heavy metals, mercury, and organic pollutants, including PFAS.&nbsp;Through practical guidance and real-world examples, we will explore how advanced digestion, extraction, and direct analysis tools streamline workflows, minimize errors, and improve data quality. Participants will gain actionable strategies to enhance productivity and achieve more reliable environmental results across the entire sample-to-analysis journey.<h4>Episode 1: New microwave digestion tools for heavy metals analysis of environmental samples</h4>Closed-vessel microwave digestion has become the benchmark for preparing environmental samples for trace metals analysis. As laboratories face growing demands for faster turnaround, improved accuracy, and lower operational costs, modern microwave platforms offer significant advantages. This webinar introduces the new Milestone’s digestion solutions, including ETHOS LEAN, ETHOS, and ultraWAVE 2 eco, and demonstrates how they improve sample throughput, minimize reprocessing, and enhance data quality. Through practical examples and best practices, attendees will learn how these new tools streamline daily workflows and reduce the overall cost per sample while supporting even the most challenging environmental applications.<blockquote><a target="_blank" rel="noopener noreferrer" href="https://share.hsforms.com/1b7diMdH_QtaH4bNUuW_T9Q5dmem">Register HERE</a></blockquote><blockquote>🎤Speaker: Giulio Colnaghi (Marketing Manager, Milestone Srl)</blockquote>

Milestone: Environmental Sample Prep Series 2026

New microwave digestion tools for heavy metals analysis of environmental samples

How advanced microwave digestion systems streamline environmental heavy metals analysis, improving efficiency, data quality, and cost per sample in modern labs.

Microwave digestion tools for heavy metals analysis

Developing next‑generation energy storage systems demands a deeper, more precise understanding of electrochemical behavior, including how to optimize electrode composition and ensure chemical homogeneity throughout the electrode structure. Combining electrochemistry with Infrared and Raman spectroscopy offers a powerful approach for achieving these goals. Pairing these techniques with microscopy further enables micrometer-scale insights into chemical composition and distribution.This 20-minute TechTalk will explore how these capabilities come together with four key instruments that make this integrated approach possible: INVENIO, RAMANtouch, HYPERION II and VERTEX NEO R.Join Dr. Sergey Shilov, Senior Application Scientist, Bruker Optics, as he shares his 40+ years of FTIR and Raman knowledge to inspire and accelerate your research in batteries, fuel cells, and advanced energy materials.<h4>Key learning objectives:</h4><ul><li>Understand spectroelectrochemical tools and workflows for probing reactions at electrodes and within electrolytes.</li><li>Learn how to optimize instrument setup and integration, including effective communication between potentiostats and spectrometers.</li><li>Understand how to apply fast chemical imaging techniques to visualize electrode surfaces and reaction dynamics.</li><li>Explore real‑world electrochemical case studies such as metal–organic complex oxidation, polymer distribution mapping, electrode degradation analysis, and SEI characterization in lithium metal batteries.</li></ul><h4>Who should attend?</h4><ul><li>Chemists, battery engineers, and scientists who are developing new materials for energy storage.</li></ul><h4>Certificate of attendance</h4><ul><li>If you attend the live TechTalk, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.</li><li>If you view the on-demand TechTalk, you can request a certificate of attendance by emailing editor@selectscience.net.</li></ul><blockquote>Presenter: Dr. Sergey Shilov (Senior Application Scientist, Bruker Optics)Dr. Sergey V. Shilov is a Senior Application Scientist and &nbsp;Product Manager for North America at Bruker Optics. Dr. Shilov is responsible for the support and development of new applications for the Bruker research FTIR systems. He received his Ph.D. in 1992 from the Russian Academy of Sciences in Polymer Physics. He has published 37 papers in peer-reviewed journals and his research interests include time-resolved FTIR spectroscopy, surface science, polymer, and life science applications.&nbsp;</blockquote>

SelectScience: Advancing energy storage with spectroelectrochemistry

Advancing energy storage with spectroelectrochemistry

How electrochemistry, FTIR, Raman spectroscopy, and microscopy enable advanced chemical insight into electrodes for next-generation energy storage systems.

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div>This webinar, titled “Process Raman as a Reliable, Versatile Tool for Downstream Process Monitoring and mAb Production Control,” explores how process Raman spectroscopy can improve the efficiency of in-line monitoring of protein concentration.The presentation highlights how process Raman spectroscopy offers several advantages over traditional in-line UV-Vis analysis for process monitoring and metabolite production control. These advantages include both time and cost efficiencies, making Raman spectroscopy a powerful tool for enhancing downstream processes and production control.<h4>You will learn:</h4><ul><li>How process Raman spectroscopy is used for protein analysis</li><li>How to develop a Raman-based protein quantification model</li><li>The Raman model advantages over established UV-Vis monitoring practices</li></ul><blockquote>Presenter: Nimesh Khadka, PhD (Sr. Product Application Specialist, Thermo Fisher Scientific)Nimesh Khadka is a senior application scientist with at Thermo Fisher Scientific with specializing in analytical biochemistry, spectroscopy, and chemometrics. With more than 5 years of experience in process development and PAT, he currently champions Raman spectroscopy as a PAT for development of biotherapeutics therapeutics.Nimesh completed his PhD at Utah State University focusing on enzymology, spectroscopy, and alternative bioenergy. In his postdoctoral training at Case Western Reserve University, Nimesh focused on the study of structural biology in biomolecules associated with eye pathologies. Through this extensive background, Nimesh has a deep understanding of the intricacies of biomolecular structures and their broad applications.</blockquote></div></div></div>

Thermo Fisher Scientific: Process Raman: A Reliable and Versatile Tool For Downstream Process Monitoring and Control For mAB Production

Process Raman: A Reliable and Versatile Tool For Downstream Process Monitoring and Control For mAB Production

How process Raman spectroscopy offers several advantages over traditional in-line UV-Vis analysis for process monitoring and metabolite production control. 

Process Raman For Downstream Process For mAB Production

As the use of permanent magnet electric motors grows, so does the interest in analyzing rare earth element (REE) content in their magnets. Heavy REEs, added at concentrations of 1–8%, play a crucial role in boosting these magnets’ resistance to high temperatures.Interest has grown following China’s Ministry of Commerce Announcement No. 18 in April 2025, restricting exports of several medium and heavy rare earth elements—such as Sm, Gd, Tb, Dy, Lu, Sc, and Y—followed by Announcement No. 57 in October 2025, which brought Ho, Er, Tm, Eu, and Yb under similar controls.Traditionally, REE analysis relies on sample digestion and ICP‑based techniques. In contrast, X‑ray fluorescence (XRF) spectrometry offers faster workflows by eliminating digestion, reducing reagent consumption, and supporting high‑volume elemental analysis. And with a small and focused analysis spot, advanced XRF analyzers excel at examining small magnets—including those within partially assembled or partially disassembled electric motors—without the need for complex sample preparation.As global magnet recycling rates remain low, demand for effective reprocessing is increasing. XRF technology helps meet this demand by enabling rapid and accurate material identification and elemental analysis.Attendees will explore real‑life cases where small‑spot ED‑XRF enables the analysis of compact, mounted, or partially disassembled magnets, demonstrating how modern solutions streamline magnet quality control and recycling workflows.<h4>Why attend:</h4><ul><li>Gain practical insights on integrating ED‑XRF into rare earth element workflows for faster decision‑making</li><li>Understand how ED‑XRF supports regulatory compliance and recycling initiatives</li><li>Improve laboratory efficiency with methods that minimize sample preparation</li></ul><h4>Who Should Attend:</h4><ul><li>Quality control and process optimization professionals</li><li>Laboratory and production managers</li><li>Anyone interested in advanced analytical technologies</li></ul>The webinar will take place on Thursday, February 5, and will take around 30 minutes, after which we'll answer your questions live.<h4>Join us live:</h4><ul><li>9:30 AM CET (Berlin); 4:30 PM SGT (Singapore) — Time Slot 1</li><li>11:00 AM EST (New York); 5:00 PM CET (Berlin) — Time Slot 2</li></ul><blockquote>Presenter: Dirk WissmannDirk Wissmann is the Product Manager for XRF instruments at SPECTRO Analytical Instruments and is responsible for the strategic development of the complete product line including application development and product support. Dirk’s experience in spectroscopy began with his graduate work in physics at the university in Siegen, Germany. He moved to SPECTRO in 1990 with assignments in quality control, training, application development, and marketing.</blockquote>

SPECTRO / AMETEK: Rare Earth Magnet Analysis: The Role of XRF in Production and Recycling

Rare Earth Magnet Analysis: The Role of XRF in Production and Recycling

Discover how ED-XRF simplifies rare earth element analysis in permanent magnets. Faster workflows, minimal prep, and practical insights for QC and recycling.

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