<p><strong>This leaflet is intended as a comprehensive checklist outlining the key steps to consider when participating in a proficiency testing (PT) scheme. Selection of an appropriate PT scheme must be ensured [1]. It provides essential tips to help participants avoid common mistakes and achieve successful outcomes. The main stages of PT participation are covered, from receipt of PT items through to the review of received evaluations [1-3]. Documentation of outcomes for many of the topics addressed below is recommended, particularly for accreditation purposes.&nbsp;</strong></p><h4><strong>1. Prior to PT participation&nbsp;</strong></h4><ul><li>Verify that the PT provider has up-to-date billing, shipping and technical contact information for the laboratory.&nbsp;</li><li>Ensure that the laboratory has documented procedures in place or, if necessary, prepare procedures for: reviewing PT results upon receipt; taking corrective actions when assessments indicate poor performance; conducting periodic reviews of PT results over time; storing PT reports.&nbsp;</li></ul><h4><strong>2. Receipt of PT items&nbsp;</strong></h4><ul><li>Open the package of PT items immediately upon receipt to check their condition. Contact the PT provider and request a replacement if any PT items are missing, broken, leaking or otherwise compromised.&nbsp;</li><li>Study the PT provider’s instructions carefully to ensure they are clear and understandable (e.g. handling, storage, pre-treatment, preparation, reporting of results).&nbsp;</li><li>Register, identify, and mark the PT items according to normal procedures in the laboratory.&nbsp;</li><li>Store the PT items in accordance with any instructions provided.&nbsp;</li></ul><h4><strong>3. Measurements&nbsp;</strong></h4><ul><li>Read the instructions supplied by the PT provider carefully before starting the measurements.&nbsp;</li><li>Carry out the measurements under conditions as close as possible to routine testing, unless otherwise instructed by the PT provider.&nbsp;</li><li>Ensure that the analysis is carried out to meet any measurement deadline requirements.</li></ul><h4><strong>4. Reporting results&nbsp;</strong></h4><ul><li>Allow sufficient time for reporting the results to the PT provider.&nbsp;</li><li>Report all the information required by the PT provider.&nbsp;</li><li>Ensure that the results are reported in the requested format (e.g. units, number of significant figures, decimal places).&nbsp;</li><li>Ensure that the results you are going to submit are those that you intend, correcting for any identified transcription errors (e.g. mix-up of samples or analytes).&nbsp;</li><li>Confirm that the submission process of the results to the PT provider has been completed.&nbsp;</li></ul><h4><strong>5. Reviewing PT reports&nbsp;</strong></h4><ul><li>Read the PT report as soon as possible and check that your results and other information are correctly represented; report any errors immediately to the PT provider.&nbsp;</li><li>Take notice of any comments on the specific PT round, evaluation of performance, and other matters relevant to the results of the PT round which provide valuable context to your individual results.&nbsp;</li><li>Review your assessed performance carefully in accordance with your laboratory procedures.&nbsp;</li><li>Store the PT report according to internal procedures.&nbsp;</li></ul><h4><strong>6. Follow-up on participation in a PT scheme&nbsp;</strong></h4><ul><li>Investigate any poor performance in accordance with your laboratory quality system [4].&nbsp;</li><li>Evaluate the impact of poor performance (e.g. risk that poor quality data may have been reported to customers).&nbsp;</li><li>Implement any corrective actions as relevant, and if possible, make use of any surplus PT items [5] to assess effectiveness.&nbsp;</li><li>Monitor any trends in performance over time, concentration levels, etc.&nbsp;</li></ul><blockquote><p>Information about PT providers and PT schemes can be obtained from your national accreditation body, from the <a target="_blank" rel="noopener noreferrer" href="https://www.eptis.org/"><strong>EPTIS website</strong></a> or from other national or international organizations.</p></blockquote>

Basic instructions for participants in a proficiency testing scheme

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 9th March 2026? Check out new documents from the field of spectroscopy/spectrometry and related techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><strong>LabRulezGCMS</strong></a> libraries.</p></blockquote><p>This week we bring you application notes by <strong>Agilent Technologies</strong>, <strong>Metrohm,</strong> <strong>Shimadzu </strong>and<strong> Thermo Fisher Scientific!</strong></p><h3><strong>1. Agilent Technologies: Spectral Transmission Measurements of Pharmaceutical Packaging</strong></h3><p><strong>Using the </strong><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=Cary+60+UV%E2%80%91Vis"><strong>Agilent Cary 60 UV‑Vis</strong></a><strong> Diffuse Reflectance Accessory following EP &lt;3.2.1&gt;, USP &lt;660&gt;, and USP &lt;661.2&gt;</strong></p><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_pharmaceutical_packaging_transmission_cary_60_uv_vis_dra_5994_8889en_agilent_2c933e5576.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Pharmaceutical containers play a significant role in maintaining final drug stability, integrity, and safety, from manufacturing to distribution to the end user. The ability of the packaging system to protect the drug from external agents is critical for quality assurance. Therefore, all pharmaceutical packaging systems must conform to stringent standards.&nbsp;</p><p>Plastic and glass are commonly used materials for packaging, and they are typically transparent or opaque. Transparency to ultraviolet (UV) light can pose a risk to light‑sensitive pharmaceuticals, as exposure can initiate adverse—and sometimes harmful—photochemical reactions that can significantly affect drug quality and reduce shelf-life.<sup>1</sup>&nbsp;</p><p>The EP and USP define well-established standards, designed to measure physiochemical and functional properties of packaging components intended to contain a drug product (pharmaceutical containers), to meet regulatory requirements. The EP Chapter &lt;3.2.1&gt; Glass Containers for Pharmaceutical Use includes a functionality test method to demonstrate adequate light resistance of colored glass containers through spectral transmission measurement. An included acceptance criterion specifies the allowed maximum amount of light transmitted by the tested material, defined by the drug product dosage administration form. For example, for glass containers that package oral drug products, the acceptance criterion defines that the observed spectral transmission should not exceed 10% at any wavelength in the range of 290 to 450 nm (&lt; 10%T).<sup>2</sup> The identical test and criterion are found in USP Chapter &lt;660&gt; Containers – Glass.<sup>3</sup> In addition, the USP Chapter &lt;661.2&gt; Plastic Packaging Systems for Pharmaceutical Use also includes the analogous functionality test method and acceptance criterion for plastic pharmaceutical packaging.<sup>4&nbsp;</sup></p><p>The <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=Cary+60+UV%E2%80%91Vis"><strong>Cary 60 UV-Vis spectrophotometer</strong></a>, equipped with the Cary 60 UV-Vis DRA, was chosen for measurement due to its extended ability to reliably measure precise transmission of scattering materials (Figure 1). The Cary 60 UV-Vis is a versatile spectrophotometer; however, measuring materials like plastics and glass, which are textured, translucent, or opaque in a manner that scatters light can result in challenges in satisfactorily measuring light transmittance with standard techniques. In a standard spectrophotometer, scattering materials tend to diffuse transmitted light, deviating an unquantifiable amount of light from the direct optical path of the detector. The detector may not collect all the scattered (lost) light, resulting in inaccurate measurements and results.&nbsp;</p><p>For this reason, the Cary 60 UV-Vis was equipped with an internal DRA, which uses a 50 mm integrating PTFE-coated sphere that easily sits inside the spectrophotometer's sample compartment. For these applications, using a DRA can optimize light collection. The sphere's design captures all scattered light uniformly, overcoming scattering losses for accurate measurement of transmitted light. In applications where total transmission is crucial for quality assurance, the DRA is an essential tool for accurate measurements.</p><h4><strong>Conclusion&nbsp;</strong></h4><p>In this application note, an Agilent Cary 60 UV-Vis spectrophotometer, fitted with an Agilent Cary 60 UV‑Vis DRA, was used to reliably and quickly determine the spectral transmission of packaging systems used for pharmaceuticals, following the EP &lt;3.2.1&gt;, USP &lt;660&gt;, and USP &lt;661.2&gt; test methods for functionality of light-resistant packaging systems. The integrating sphere enabled the instrument to accurately measure total transmittance of plastic and glass (scattering) materials.&nbsp;</p><p>All containers presented less than the defined maximum %T specification, demonstrating light-resistance functionality for containing light-sensitive drug products for oral administration. This method illustrates the importance of accurate testing for quality assurance of pharmaceutical packaging. The Agilent Cary 60 UV-Vis spectrophotometer, paired with Cary WinUV Pharma software, delivers secure data management and compliance for regulated pharmaceutical labs.</p><h3><strong>2. Metrohm: Multiparameter hops analysis by near-infrared spectroscopy (NIRS)</strong></h3><p><strong>Rapid determination of alpha acids, beta acids, cohumulone content, total oil content, HSI, and moisture</strong></p><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_nir_130_download_6177b89ee1.pdf"><strong>Full PDF for download</strong></a></li></ul><p>The quality of hops and hop pellets is vital across the entire brewing supply chain. Traditional methods used for quality control (e.g., titration and HPLC) are highly accurate and widely accepted. They are also time consuming, labor intensive, and dependent on chemical reagents which not only incur ongoing material costs but also require careful handling and proper disposal. Near-infrared spectroscopy (NIRS) offers a compelling alternative when ultra-high precision is not necessary. It enables the rapid analysis of multiple parameters within a minute without using any chemicals. This Application Note outlines the measurement setup and the results of cohumulone, hop oils, and moisture content, the hop storage index (HSI), and hops acids analysis with NIRS.</p><h4><strong>EXPERIMENTAL EQUIPMENT&nbsp;</strong></h4><p>More than 500 fresh hop samples and ground hop pellets were analyzed on an <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=220&amp;search=omnis+nir"><strong>OMNIS NIR Analyzer Solid</strong></a> (Figure 1). The samples were added to an OMNIS sample cup and analyzed in diffuse reflection mode. To include sample variety, the sample rotated during measurement to collect spectra from different locations. The automatically averaged spectra were used for model development. Spectra acquisition, model development, and validation were carried out with the OMNIS Software.&nbsp;</p><p>Reference values for alpha acids were obtained using various official methods, including EBC 7.4, EBC 7.5, and EBC 7.7. Total oils and beta acid content were determined using EBC 7.4, while EBC 7.7 was employed for cohumulone analysis. Moisture content and the hop storage index (HSI) were measured using a halogen moisture analyzer and a UV-VIS photometer, respectively.</p><h4><strong>CONCLUSION</strong></h4><p>This Application Note demonstrates the feasibility of using NIR spectroscopy for the analysis of freshly harvested hops and ground hop pellets to determine cohumulone, moisture, and total oil content, HSI, and alpha and beta acids. Using alpha acids as an example, the difference between a prediction model covering the full concentration range and a model specific to a narrower range was highlighted. The latter reduced the prediction error by a factor of two.&nbsp;</p><p>Users can apply this approach to maximize accuracy. In the OMNIS Software, both models can be combined to automatically perform the following sequence. First, the alpha acid concentration is estimated using the broad-range model; then, a more precise prediction is made using the restricted-range model.</p><h3><strong>3. Shimadzu: Observation of Acrylic Block Fracture during Impact Compression Using the Hopkinson Bar Method</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_01146_en_dc42e77a9c.pdf"><strong>Full PDF for download</strong></a></li></ul><h4><strong>User Benefits</strong></h4><ul><li>The HPV -X3 offers three times the resolution of conventional models, enabling observation of specimen fracture at much higher resolution.</li><li>With a maximum frame rate of 20 Mfps, the HPV-X3 is well-suited for observing high-speed phenomena such as an impact test</li></ul><p>Understanding materials properties is critical to product design. In particular, for applications such as transportation equipment, where materials may be subjected to impact loads, it is essential to evaluate not only static properties but also impact properties. When subjected to impact, materials may exhibit stress and strain characteristics different from those under static loading, making it essential to quantify these characteristics through impact testing.&nbsp;</p><p>The Hopkinson bar method is a well-established technique for impact compression testing. Proposed by B. Hopkinson, this method enables detailed analysis of a material’s impact response and evaluation of its fracture properties by subjecting the specimen to a sudden force using a bar-launching device. This paper presents an example of an impact compression test on an acrylic specimen with a central circular hole, recorded with an HPV-X3 high-speed video camera (Fig. 2) using the Hopkinson bar method.</p><h4><strong>Imaging System&nbsp;</strong></h4><p>The imaging devices are listed in Table 1, and the imaging conditions are listed in Table 2. As shown in Fig. 4(b), laser illumination was directed from the rear of the specimen toward the lens, and imaging was performed with the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=1&amp;search=HPV-X3"><strong>HPV-X3</strong></a> using a close-up ring, bellows, and macro lens. This setup enabled observation of the fracture process in the acrylic block. Two types of imaging were conducted: observation of crack propagation immediately after loading, and observation of subsequent fracture.</p><h4><strong>Conclusion&nbsp;</strong></h4><p>The impact compression test of an acrylic specimen using the Hopkinson bar method was observed using the HPV-X3 highspeed video camera. Inside the compressed specimen, the propagation of a wavefront believed to be a stress wave was first observed. Subsequently, cracks propagated from the central circular hole toward the left and right surfaces, and finally, diagonal cracks formed, leading to complete fracture. The progress of this series of fracture processes was clearly captured.&nbsp;</p><p>The HPV-X3 has three times the resolution of the previous <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=1&amp;search=HPV-X2"><strong>HPVX2 model</strong></a>, enabling more detailed observation of specimens during impact tests, including the Hopkinson bar method. Furthermore, because fracture phenomena during impact testing occur at high speeds, the HPV-X3, which can record images at up to 20 Mfps, is ideal for capturing them.</p><h3><strong>4. Thermo Fisher Scientific: Analysis of silica in air filters using ARL X’TRA Companion X-ray Diffractometer</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/analysis_of_silica_in_air_an41521_a3b8eb33d5.pdf"><strong>Full PDF for download</strong></a></li></ul><p>The analysis of silica in air filters is a critical aspect of occupational health and safety, aimed at protecting workers from the harmful effects of inhaling crystalline silica particles, which can lead to diseases such as silicosis and lung cancer. The NIOSH 7500 method (NIOSH, 2003) provides a detailed and standardized procedure for the determination of crystalline silica in air samples using X-ray diffraction (XRD). This method involves the collection of air samples on filters, which are then analyzed to identify and quantify the crystalline silica phases, including quartz, cristobalite, and tridymite.&nbsp;</p><p>XRD is chosen for its high specificity and sensitivity in distinguishing different crystalline forms of silica, making it a reliable analytical technique. The method outlined in NIOSH 7500 requires meticulous sample preparation, including the proper collection and handling of air filters, calibration with known standards, and strict adherence to analytical parameters to ensure accurate and reproducible results. Following the NIOSH 7500 norm and equivalent standards helps ensure the reliable monitoring of workplace air quality, thereby safeguarding workers’ health. The use of XRD in analyzing silica in air filters is an essential component of industrial hygiene and environmental monitoring programs, facilitating the detection and control of hazardous silica exposure in occupational settings.</p><h4><strong>Instrument and software&nbsp;</strong></h4><p>The <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2296"><strong>Thermo Scientific™ ARL™ X’TRA Companion X-ray Diffractometer</strong></a> (c.f. Figure 1) is a simple, easy-to-use benchtop XRD instrument for routine phase analysis as well as more advanced applications. The ARL X’TRA Companion XRD uses a θ/θ goniometer (160 mm radius) in Bragg-Brentano geometry coupled with a 600 W X-ray source (Cu or Co). The radial and axial collimation of the beam is controlled by divergence and Soller slits, while air scattering is reduced by a variable beam knife. An integrated water chiller is available on demand. Thanks to the innovative solid state pixel detector (55 x 55 μm pitch), the ARL X’TRA Companion XRD provides very fast data collection and comes with one-click Rietveld quantification capabilities and automated result transmission to a LIMS (laboratory information management system).</p><h4><strong>Your benefits&nbsp;</strong></h4><p>The ARL X’TRA Companion XRD provides data perfectly suited to quantify respirable quartz in air filters. Utilizing a calibration curve in a one-click refinement delivers results within minutes, ensuring ease-of-use for operators and reducing training requirements. XRD analysis of air filter samples complies with the NIOSH 7500 standard.</p>

News from LabRulezICPMS Library - Week 11, 2026

<p><strong>How can we make the production of supercapacitors for energy storage more sustainable and replace the traditionally used but toxic solvent NMP (N-methyl-2-pyrrolidone)? According to scientists from CATRIN at Palacký University, the “green” solvents Cyrene and Tamisolve may be a suitable alternative. In an article published in the </strong><a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1385894725130696?via%3Dihub#s0060"><i><strong>Chemical Engineering Journal</strong></i></a><strong>, they have shown that these solvents can be used in production without reducing the performance of the equipment. They thus offer a path to the next generation of sustainable, high-performance supercapacitors for industrial use.</strong></p><p>“<i>Supercapacitors are one of the modern technologies for storing electric energy. As sustainable energy storage becomes more prominent, it is essential to replace the hazardous solvents used in the production of supercapacitor electrodes. Our study presents Cyrene and Tamisolve as environmentally friendly alternatives to the toxic solvent NMP, which is traditionally used in production. Both tested solvents enabled the preparation of electrodes that maintain high electrochemical performance while improving environmental compatibility</i>,” said <strong>Michal Otyepka</strong>, <strong>corresponding author</strong> of the article.</p><p>The electrodes were prepared using nitrogen-doped graphene as the active material in combination with two types of binders. The first was a common fluorinated binder (PVDF), which is widely used in industry, including in the manufacturing of battery electrodes. The researchers also tested a fluorine-free binder (PVP), which has a lower environmental impact and is more soluble in environmentally friendly solvents. Using various combinations, they monitored the performance and stability of the electrodes as well as their mechanical resistance.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CATRIN_Vedci_z_CATRIN_nabizeji_zelenejsi_cestu_pro_vyrobu_superkondenzatoru_443775296a.jpg" alt="CATRIN: CATRIN researchers offer a “greener” way to make supercapacitors" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CATRIN_Vedci_z_CATRIN_nabizeji_zelenejsi_cestu_pro_vyrobu_superkondenzatoru_443775296a.jpg 245w," sizes="100vw" width="1536" height="768"></p><p>“<i>The results showed that not only can the alternative solvents Cyrene and Tamisolve fully replace the toxic solvent NMP, but also that the prepared electrodes have the necessary mechanical properties. Their compatibility with both fluorinated PVDF and non-fluorinated PVP binders, together with excellent layer uniformity and electrochemical stability, makes them ideal for use in scalable applications. This is essential for industrial production,</i>” said the publication’s <strong>first author, Ivan Dědek</strong>.</p><p>Cyrene, or dihydrolevoglucosenone, is obtained from renewable biomass sources such as cellulose. Tamisolve (N-butyl-2-pyrrolidone) is a substance related to the commonly used NMP, but is more gentle on human health and the environment.</p><p>Supercapacitor research has been a priority at CATRIN for almost ten years. In addition to developing new active materials, such as the successful nitrogen-doped graphene (SC-GN3), it also focuses on environmentally friendly and industrially feasible manufacturing processes. The replacement of toxic NMP with the “greener” solvents Cyrene and Tamisolve confirms that more sustainable production can go hand in hand with high performance and represents an important step towards industrial implementation.</p><blockquote><h4><strong>The original article</strong></h4><h4><a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1385894725130696?via%3Dihub#s0060"><strong>Toward transitioning to green and sustainable supercapacitors</strong></a></h4><p>Ivan Dědek, Vojtěch Kupka, Veronika Šedajová, Petr Jakubec, Matěj Navrátil, Michal Otyepka&nbsp;</p><p>Chemical Engineering Journal, 529, 2026, 172220</p><p><a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1016/j.cej.2025.172220">https://doi.org/10.1016/j.cej.2025.172220</a></p><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/"><strong>CC-BY 4.0</strong></a></h6></blockquote><h4><strong>Abstract</strong></h4><p>The rapid advancement of supercapacitor technologies has intensified the demand for sustainable electrode fabrication methods that minimize environmental impact. A major challenge arises from the extensive use of the toxic solvent N-methyl-2-pyrrolidone (NMP), which is subject to increasingly stringent regulatory restrictions. We demonstrate that NMP can be effectively replaced with two green solvents, dihydrolevoglucosenone (Cyrene) and N-butyl-2-pyrrolidone (Tamisolve), without compromising electrochemical performance. Electrode formulations were prepared using nitrogen-doped graphene as the active material, in combination with either polyvinylidene fluoride (PVDF), a widely employed fluorinated binder, or polyvinylpyrrolidone (PVP), a non-fluorinated alternative with improved environmental profile. Optimized coatings exhibited high mass loadings exceeding 6 mg cm−2 while maintaining strong adhesion to current collectors, an often overlooked yet critical parameter for scalable manufacturing. Electrochemical testing revealed that PVDF in Cyrene delivered an energy density of 66.6 Wh kg−1 at a power density of 1.85 kW kg−1, with excellent cycling stability, retaining 91 % of capacitance after 100,000 cycles. PVP in Cyrene provided a more environmentally benign alternative, achieving an energy density of 64.2 Wh kg−1 at 1.80 kW kg−1, with 78 % capacitance retention after 100,000 cycles, thereby highlighting the trade-off between performance and sustainability.</p>

CATRIN researchers offer a “greener” way to make supercapacitors

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Scientific article

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Eurachem is a European network promoting international traceability of chemical measurements and good analytical practice. It provides expert guidance, supports method validation, uncertainty evaluation, proficiency testing, and facilitates discussion on technical and policy issues in analytical quality.

Eurachem

The Czech Advanced Technology and Research Institute (CATRIN) at Palacký University is a cutting-edge scientific hub dedicated to advancing research in the fields of nanotechnology, biotechnology, and biomedicine. At its core, CATRIN boasts outstanding scientific teams, featuring international researchers. We emphasize interdisciplinarity, foster global collaborations, and work to translate our research findings into practical applications.

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Thermo Scientific™ picoSpin™ 80 Series II NMR Spectrometer

Benchtop 82 MHz NMR spectrometer with high resolution and no cryogens. Ideal for teaching, reaction monitoring, and small-molecule analysis in any lab.

<div><h4><strong>Compact, high-resolution benchtop NMR for education, research, and process control</strong></h4><p><strong>The picoSpin™ 80 Series II NMR spectrometer brings the power of Nuclear Magnetic Resonance (NMR) to laboratories of any size. With a compact footprint, temperature-stabilized 2 Tesla permanent magnet, and proton Larmor frequency of 82 MHz, the instrument delivers chemical shift resolution below 20 ppb—unmatched among benchtop NMR systems.</strong></p><p>Designed for users of all experience levels, the picoSpin 80 is ideal for structural analysis, compound identification, reaction monitoring, and education. It operates without cryogens or deuterated solvents and requires only 40 µL of liquid sample, introduced via a replaceable capillary cartridge.</p><h3><strong>Key Benefits</strong></h3><ul><li><strong>High-resolution performance</strong> for routine small molecule applications</li><li><strong>Compact and portable</strong>—placeable on bench or near reactors</li><li><strong>Low operating cost</strong>—no cryogens, no consumables, standard power supply</li><li><strong>Easy to use</strong>—automatic shimming, minimal training required</li><li><strong>Fast data acquisition</strong>—NMR spectrum delivered in minutes</li></ul></div><h3><strong>Applications</strong></h3><p><strong>Pharmaceutical &amp; Chemical Research</strong><br>Gain rapid insight into reaction progress and sample composition without relying on centralized NMR facilities. The 82 MHz field strength ensures better signal dispersion and structural clarity than lower-frequency desktop systems.</p><p><strong>Education</strong><br>Provide hands-on experience with real NMR spectra. The intuitive web interface and included Mnova™ software allow students to operate the instrument and analyze data independently, with no re-shimming required between measurements.</p><p><strong>Process Analysis &amp; QA/QC</strong><br>Built for rugged environments, the instrument fits easily into production labs or fume hoods. Monitor reactions in real time and ensure reproducibility through a stable magnetic field and network-based remote access.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_80_Series_II_NMR_Spectrometer_7_7a843b395f.jpg" alt="Thermo Scientific™ picoSpin™ 80 Series II NMR Spectrometer: 82MHz spectrum of Oil of Wintergreen resolves neighboring multiplets and reveals small couplings." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_80_Series_II_NMR_Spectrometer_7_7a843b395f.jpg 200w," sizes="100vw" width="1056" height="825"></p><h3><strong>Interface &amp; Data Handling</strong></h3><ul><li><strong>Web-based control</strong> from PC, tablet, or smartphone</li><li><strong>Data export</strong> in JCAMP-DX format, compatible with most NMR software</li><li><strong>Mnova™ software license</strong> included (1 year) for advanced analysis</li><li><strong>Ethernet connectivity</strong> for remote monitoring and control</li></ul><h3><strong>Technical Specifications</strong></h3><ul><li><strong>Magnet</strong>: 2 Tesla rare earth permanent, temperature stabilized</li><li><strong>Larmor Frequency</strong>: 82 ± 2 MHz (proton)</li><li><strong>Spectral Resolution</strong>: ≤ 20 ppb FWHM</li><li><strong>Sample Volume</strong>: 40 µL (injected via syringe)</li><li><strong>Capillary Cartridge</strong>: 400 µm ID, 1/16 in. fittings, user replaceable</li><li><strong>Power Supply</strong>: 100–230 V AC, 50/60 Hz, 150 W</li><li><strong>Environmental Requirements</strong>: Standard lab environment, no cryogens or compressed gases</li><li><strong>Dimensions</strong>: 43 × 35.6 × 25.4 cm</li><li><strong>Weight</strong>: 19 kg (43 lb)</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_80_Series_II_NMR_Spectrometer_4_267f669007.jpg" alt="Thermo Scientific™ picoSpin™ 80 Series II NMR Spectrometer: Easily operate your system through a web-browser for remote access, automatic shimming and single-click data collection." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_80_Series_II_NMR_Spectrometer_4_267f669007.jpg 222w," sizes="100vw" width="1053" height="739"></p>

Thermo Scientific™ picoSpin™ Accessories

Enhance your nuclear magnetic resonance (NMR) spectroscopy analysis with a complete set of accessories designed to help you get the most from your Thermo Scientific™ picoSpin™ NMR Spectrometer.

<div><div><p><strong>Enhance your nuclear magnetic resonance (NMR) spectroscopy analysis with a complete set of accessories designed to help you get the most from your Thermo Scientific™ picoSpin™ NMR Spectrometer. Whether in the classroom or in a chemical manufacturing QA/QC lab, valuable picoSpin accessories will help you achieve the progress that only personal NMR can offer for your research, teaching or process applications.</strong></p></div><div><h3><strong>Choose from these picoSpin accessories:</strong></h3><h4><strong>Benchtop NMR Reaction Monitoring Accessory</strong></h4><p>Adding a reaction monitoring accessory to the <strong>Thermo Scientific™ &nbsp;picoSpin™ 45</strong> or the <strong>picoSpin 80 NMR spectrometer</strong> gives organic chemistry students valuable hands-on experience of chemical reaction mechanisms, kinetics, &nbsp;thermodynamics, and other physical organic properties to complement the core of your undergraduate chemistry curriculum.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_Accessories_16_4378eed143.jpg" alt="Thermo Scientific™ picoSpin™ Accessories: Benchtop NMR Reaction Monitoring Accessory" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_Accessories_16_4378eed143.jpg 198w," sizes="100vw" width="650" height="513"></p><p>The new reaction monitoring accessory for high-resolution benchtop picoSpin spectrometers uses a pump and computer-actuated valve operator to quickly and automatically direct samples from a chemical reaction to the spectrometer for data acquisition. The instrument generates real-time, information-rich images about the state of the chemical reaction as each NMR spectrum is automatically processed and analyzed.&nbsp;</p><p>The picoSpin NMR spectrometer’s fluid capillary system is perfectly suited to an online flow configuration; eliminates the need for fragile NMR tubes and messy preparation when the time comes for the next timed sampling of the reaction mixture.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_Accessories_17_10838af3e0.jpg" alt="Thermo Scientific™ picoSpin™ Accessories: Benchtop NMR Reaction Monitoring Accessory" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_Accessories_17_10838af3e0.jpg 245w," sizes="100vw" width="650" height="296"></p><ul><li>Reaction Monitoring lesson plan for teaching</li><li>Low-maintenance NMR accessory</li><li>Real time operation</li><li>Enhance chemistry curriculums</li><li>Provide a richer experience in spectroscopy</li><li>Integrated into an installed picoSpin instrument</li><li>Included as part of a new instrument purchase</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_Accessories_18_b8591d5e7e.jpg" alt="Thermo Scientific™ picoSpin™ Accessories: Benchtop NMR Reaction Monitoring Accessory" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_Accessories_18_b8591d5e7e.jpg 245w," sizes="100vw" width="650" height="373"></p><h4><strong>Thermo Scientific™</strong>&nbsp;<strong>picoSpin™&nbsp;NMR Classroom Kit for 1/16-inch and 1/32-inch Fittings</strong></h4><p>Each kit provides sample injection accessories for use with the picoSpin NMR spectrometer. The kits include polypropylene syringes, syringe filters, inlet and outlet port plugs, inline filters, and drain tubes. Also included are easy to use instructions describing sample injection into the picoSpin NMR spectrometer using accessories in this kit.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_Accessories_5_a6ea2283b8.jpg" alt="Thermo Scientific™ picoSpin™ Accessories: Thermo Scientific™&nbsp;picoSpin™&nbsp;NMR Classroom Kit for 1/16-inch and 1/32-inch Fittings" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_Accessories_5_a6ea2283b8.jpg 245w," sizes="100vw" width="650" height="321"></p><h4><strong>Thermo Scientific™&nbsp;picoSpin™ NMR Laboratory Kit for 1/16-inch and 1/32-inch Fittings</strong></h4><p>Each kit provides sample injection accessories for use with the picoSpin NMR spectrometer. The kits include a 100 μL Hamilton Gastight™ syringe, a 22 gauge blunt-tip needle with inlet port adapter (for 1/16-inch fittings), &nbsp;a 26s gauge blunt-tip needle with inlet port adapter (for 1/32-inch fittings), inline filter, drain tube assembly, and a pair of inlet and outlet port plugs. Instructions describing sample injection into the picoSpin NMR spectrometer using accessories are included.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_Accessories_7_8a97301229.jpg" alt="Thermo Scientific™ picoSpin™ Accessories: Thermo Scientific™&nbsp;picoSpin™ NMR Laboratory Kit for 1/16-inch and 1/32-inch Fittings" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_Accessories_7_8a97301229.jpg 245w," sizes="100vw" width="650" height="351"></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_Accessories_15_0f8ec6822c.jpg" alt="Thermo Scientific™ picoSpin™ Accessories: Thermo Scientific™&nbsp;picoSpin™ NMR Laboratory Kit for 1/16-inch and 1/32-inch Fittings" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_Accessories_15_0f8ec6822c.jpg 245w," sizes="100vw" width="650" height="292"></p><h4><strong>Thermo Scientific™&nbsp;picoSpin™ Inline Filter Kit</strong></h4><p>This kit provides inlet filters for use with the picoSpin NMR spectrometer. The kit includes a 5 replacement, 2 μm stainless steel mesh inlet filters for 1/16-inch fittings.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_Accessories_4_f203223c20.jpg" alt="Thermo Scientific™ picoSpin™ Accessories: Thermo Scientific™&nbsp;picoSpin™ Inline Filter Kit" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_Accessories_4_f203223c20.jpg 245w," sizes="100vw" width="650" height="400"></p><h4><strong>Mnova™ NMR</strong>&nbsp;</h4><p>The Mnova NMR plugin is ideal both for the non-expert NMR user looking for an easy to learn software which delivers quick, high quality results, and for the expert user looking for extensive advanced functionality.</p><h4><strong>Mnova™&nbsp;NMRPredict Desktop</strong></h4><p>NMRPredict Desktop allows Prediction of 1D (1H, 13C, 15N, 19F, 31P, 17O, 29Si) and HSQC from molecular structure (mol file, ChemDraw, IsisDraw, ChemSketch) within Mnova. Easily combine and compare experimental and predicted data as part of your workflow and leverage your company’s unique knowledge.</p><h4><strong>Travel Case for the&nbsp;Thermo Scientific™&nbsp;picoSpin™ 80 NMR</strong></h4><p>Make the most of system portability with a handy travel case.</p><h4><strong>Replacement Capillary Cartridge</strong></h4><p>The replacement Capillary Cartridge includes the fluid sub-panel assembly, the sample capillary, the NMR RF coil and the NMR shim coils. Replacement of the Capillary Cartridge is necessary when the 300 μm ID sample delivery tubing becomes clogged or contaminated. &nbsp;To minimize downtime it is advisable to keep a spare cartridge in stock. &nbsp;The picoSpin Capillary Cartridge comes complete with the tools needed for installation and removal. Capillary cartridges come standard with 1/16-inch fittings. Cartridges with 1/32-inch fittings are available by special order.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_Accessories_11_c087685ee3.jpg" alt="Thermo Scientific™ picoSpin™ Accessories: Replacement Capillary Cartridge" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_Accessories_11_c087685ee3.jpg 245w," sizes="100vw" width="650" height="206"></p><h4><strong>Thermo Scientific™&nbsp;picoSpin™ Cartridge Maintenance Kit for 1/32-inch Fittings</strong></h4><p>This kit provides accessory items needed to perform maintenance on the capillary inlet filter of the picoSpin NMR spectrometer. &nbsp;The kit includes 1/4” and 3/16” inch open-end box wrenches, 10 replacement 2 μm frit filters, and 2 short pieces of wire to help with the removal of frit. &nbsp;Instructions are included describing how to ‘back-flush’ clean the existing frit filter and how to replace a frit filter.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_Accessories_14_8f72ac1f3b.jpg" alt="Thermo Scientific™ picoSpin™ Accessories: Thermo Scientific™&nbsp;picoSpin™ Cartridge Maintenance Kit for 1/32-inch Fittings" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_Accessories_14_8f72ac1f3b.jpg 241w," sizes="100vw" width="650" height="421"></p></div></div>

Thermo Scientific™ picoSpin™ 45 Series II NMR Spectrometer

Affordable, compact NMR spectrometer for research, education, or QC. 30 μL sample volume, web GUI, auto shimming, replaceable capillary, and 1-year Mnova™ software license included.

<div><div><p><strong>Get a dedicated NMR spectrometer for your research, manufacturing process, or classroom with the affordable Thermo Scientific™ picoSpin™ 45 Series II NMR Spectrometer. A true breakthrough in chemical instrumentation, the picoSpin 45 occupies only a fraction of the space of a conventional NMR system and requires no specialized training to operate. Simply inject 30 microliters of liquid sample into the internal capillary via front-panel fittings to obtain a high-quality spectrum.</strong></p><p>The Series II model offers streamlined workflows, a modern web-based interface, automatic shimming, and customizable methods — ideal for both novice and experienced users.</p><p>A temperature-stabilized permanent magnet ensures consistent, maintenance-free performance with no need for cryogens. NMR data is generated in the industry-standard JCAMP-DX format, compatible with common NMR analysis software. The internal capillary is housed in a replaceable cartridge, allowing users to easily swap it out if blocked or contaminated.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_80_Series_II_NMR_Spectrometer_0b279c7ee9.jpg" alt="Thermo Scientific™ picoSpin™ 45 Series II NMR Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_80_Series_II_NMR_Spectrometer_0b279c7ee9.jpg 245w," sizes="100vw" width="2505" height="1157"></p><h3><strong>Key Features:</strong></h3><ul><li>High-performance, high-resolution, compact, and portable design</li><li>Easy to use — no specialized training required</li><li>Replaceable capillary cartridge</li><li>Microcoil capillary probe</li><li>Fully programmable pulse sequencer</li><li>Ethernet connectivity</li><li>Web-based graphical user interface</li><li>Includes a one-year license for Mnova™ NMR software</li><li>Sample volume: 30 μL</li></ul><h3><strong>Specifications:</strong></h3><ul><li><strong>Capillary Cartridge:</strong> 400 µm ID, 30 µL volume, 1/16 in. fittings, user-replaceable</li><li><strong>Electrical Requirements:</strong> 100/230 V, 50/60 Hz, 150 W</li><li><strong>Environment:</strong> No cryogens or compressed gases required; standard lab environment</li><li><strong>Magnet:</strong> Rare earth permanent magnet, 1.1 Tesla, temperature stabilized</li><li><strong>Performance:</strong> Larmor Frequency 45 ± 1 MHz (proton), chemical shift resolution ≤ 40 ppb (FWHM)</li><li><strong>Data Output:</strong> JCAMP-DX format, compatible with standard NMR programs</li><li><strong>Sample Introduction:</strong> Syringe injection</li><li><strong>Dimensions (W × D × H):</strong> 14.6 × 17.8 × 29.2 cm (5.75 × 7 × 11.5 in.)</li><li><strong>Weight:</strong> 4.8 kg (10.5 lb)</li><li><strong>Unit Size:</strong> Each</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_pico_Spin_45_Series_II_NMR_Spectrometer_34cde1c4c1.jpg" alt="Thermo Scientific™ picoSpin™ 45 Series II NMR Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_pico_Spin_45_Series_II_NMR_Spectrometer_34cde1c4c1.jpg 245w," sizes="100vw" width="650" height="365"></p></div></div>

Products from category NMR from Thermo Fisher Scientific - page 1

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