A team led by scientists from CEITEC Masaryk University has uncovered the infection mechanism of tailed bacteriophages – a group of viruses that infect bacteria. These phages target, among others, Staphylococcus aureus, a major cause of bacterial infections that is often resistant to antibiotics. The bacterium belongs to a group of Gram-positive bacteria characterised by an exceptionally thick cell wall. Although the infection mechanisms of some other bacteriophages have been described previously, the way tailed phages infecting Staphylococcus aureus and other thick-walled bacteria invade their hosts had remained unknown. The researchers have now revealed how such a bacteriophage breaches the protective barrier of the bacterial cell and delivers its genetic material inside. Their findings could contribute to the development of new strategies for combating antibiotic-resistant bacteria.Staphylococcus aureus is one of the most common sources of bacterial infections in humans. It can cause skin infections, pneumonia, and even life-threatening bloodstream infections. Moreover, many of its strains have become resistant to commonly used antibiotics, increasing interest in alternative treatment approaches such as bacteriophage therapy.“Bacteriophages are the most abundant biological entities on Earth and have been infecting bacteria for billions of years. Yet we still do not fully understand how they overcome the cell wall of certain Gram-positive bacteria. By reconstructing the bacteriophage structure before and after it attaches to a bacterial cell, we were able to reveal this process,” says <a target="_blank" rel="noopener noreferrer" href="https://www.ceitec.eu/jan-binovsky-ph-d/u91173?page=publication">Ján Bíňovský</a> of CEITEC Masaryk University, who led the study together with Marta Šiborová.Bacteriophage 812, investigated in this study, specifically infects Staphylococcus aureus. The researchers discovered that once it recognises the correct host, the protein structure at the tip of its tail undergoes extensive rearrangements. Individual components of this structure, which resembles a lunar landing module, reorganise into a new configuration that enables the virus to firmly attach to the bacterial surface. At the same time, a mechanism is activated that triggers contraction of the phage tail.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Jak_zabit_zlateho_stafylokoka_novy_pohled_na_viry_ktere_si_poradi_s_bakteriemi_01c86d5e42.jpg" alt="CEITEC/Plevka Lab: How to Kill Staphylococcus Aureus: A New Insight into Viruses That Can Defeat Bacteria: Phage before attachment to the bacterial cell." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Jak_zabit_zlateho_stafylokoka_novy_pohled_na_viry_ktere_si_poradi_s_bakteriemi_01c86d5e42.jpg 245w," sizes="100vw" width="4339" height="1600"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Jak_zabit_zlateho_stafylokoka_novy_pohled_na_viry_ktere_si_poradi_s_bakteriemi_2_53422574db.jpg" alt="CEITEC/Plevka Lab: How to Kill Staphylococcus Aureus: A New Insight into Viruses That Can Defeat Bacteria: Phage attached to the bacterial cell." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Jak_zabit_zlateho_stafylokoka_novy_pohled_na_viry_ktere_si_poradi_s_bakteriemi_2_53422574db.jpg 245w," sizes="100vw" width="4085" height="1600">“The process resembles the release of an extended spring. The bacteriophage tail contracts to approximately half of its original length, and the released energy drives the central tube through the bacterium's protective layers. The virus can then deliver its genetic material into the cell and initiate infection,” explains Marta Šiborová.Unlike many other bacteria, Staphylococcus aureus possesses an exceptionally thick cell wall. The researchers therefore investigated in detail how the bacteriophage overcomes this barrier. They found that the virus employs a combination of mechanical force and enzymatic activity. Some components of its infection apparatus likely disrupt teichoic acids, which form the outer protective layer of the bacterial cell wall. Other proteins then degrade peptidoglycan, the main structural component of the cell wall. Finally, the bacteriophage penetrates the inner lipid membrane, allowing its central tube to enter the bacterial cell.The findings show that the bacteriophage does not function as a simple "needle", but rather as a sophisticated nanomachine composed of dozens of cooperating proteins.Although this is fundamental research, the findings may prove important for future medical applications. Bacteriophages are considered one of the promising alternatives for treating infections caused by antibiotic-resistant bacteria.“If we want to use bacteriophages therapeutically in the future – or even engineer them for specific medical applications – we first need to understand in detail how they work. Our study provides fundamental insight into how bacteriophages recognise their hosts and initiate infection,” says <a target="_blank" rel="noopener noreferrer" href="https://www.ceitec.eu/pavel-plevka-ph-d/u26854">Pavel Plevka</a>, structural biologist and head of a research group at CEITEC Masaryk University.<blockquote>The study, published in <a target="_blank" rel="noopener noreferrer" href="https://link.springer.com/article/10.1038/s44318-026-00834-9">EMBO Journal</a>, also involved researchers from the Faculty of Science, Masaryk University.</blockquote><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Jak_zabit_zlateho_stafylokoka_novy_pohled_na_viry_ktere_si_poradi_s_bakteriemi_3_fba5a65145.jpg" alt="CEITEC/Plevka Lab: How to Kill Staphylococcus Aureus: A New Insight into Viruses That Can Defeat Bacteria: Black = protein structure at the tip of the tail after the conformational change; red = portion of the tail that has begun to contract; blue = portion of the tail that remains extended." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Jak_zabit_zlateho_stafylokoka_novy_pohled_na_viry_ktere_si_poradi_s_bakteriemi_3_fba5a65145.jpg 245w," sizes="100vw" width="1600" height="782"><blockquote><h4>The original article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://link.springer.com/article/10.1038/s44318-026-00834-9">Conformational changes of the baseplate regulating tail contraction of Staphylococcus phage 812</a></h4>Ján Bíňovský, Marta Šiborová, Maryna Zlatohurska, Jiří Nováček, Pavol Bárdy, Roman Baška, Karel Škubník, Tibor Botka, Martin Benešík, Roman Pantuček, Konstantinos Tripsianes &amp; Pavel PlevkaEMBO J (2026)<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1038/s44318-026-00834-9">https://doi.org/10.1038/s44318-026-00834-9</a>&nbsp;<h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote>

 How to Kill Staphylococcus Aureus: A New Insight into Viruses That Can Defeat Bacteria 

The standard uncertainty arising from random effects is often derived from repeated experiments and is quantified in terms of the standard deviation s of the measured values of the quantity. If it is the standard uncertainty arising from random effects on a single measurement that is required, then the observed standard deviation s is used without change. However, for a result which is the mean x of n measurements the standard uncertainty decreases as n increases, so that:<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Using_repeated_measurements_to_improve_the_standard_uncertainty_equation_1_19f8f07f8f.jpg" alt="Eurachem: Using repeated measurements to improve the standard uncertainty - Equation 1" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Using_repeated_measurements_to_improve_the_standard_uncertainty_equation_1_19f8f07f8f.jpg 245w," sizes="100vw" width="485" height="138">Example 1 shows how Eq (1) applies when estimating the uncertainty of a mean value, but not when considering the uncertainty of individual observations.<blockquote>Example 1 A volumetric pipette is calibrated with 12 measurements; the mean and the standard deviation are calculated. Eq. 1 applies to estimate the standard uncertainty of the mean value. However, when using the pipette to deliver one aliquot, Eq. 1 does not apply and the standard uncertainty due to random variation on this single measurement is the standard deviation s</blockquote>For Eq (1) to be valid, it is a requirement that all the measurements are independent and from a stable test sample under the same measurement conditions. The measurement conditions for all the measurements could be, for example, 1) repeatability conditions, 2) intermediate precision (within laboratory reproducibility) conditions or 3) reproducibility conditions&nbsp;It is very important to be aware that the standard uncertainty given by Eq. 1 only gives the estimated uncertainty due to random variation under the conditions of measurement under which the observations were taken, and is only strictly valid for independent observations.&nbsp;It can be hard to decide whether observations are sufficiently independent for Eq. 1 to apply, as there is no simple, general, rule. The following paragraphs therefore give examples of different circumstances to help identify circumstances when Eq. 1 can safely be used.<h3>Example where Equation (1) applies&nbsp;</h3><h4>Measurement of inhomogeneous samples&nbsp;</h4>If inhomogeneity for test samples is a major part of the uncertainty the analyst may choose to measure more test portions from each test sample in order to reduce the standard uncertainty. If all these measurements are made under repeatability conditions, i.e. the same measurement conditions following the whole procedure, including repeated random sampling from the test sample, the standard deviation of the mean, given by Eq. (1), should be used to estimate the uncertainty arising from variation under repeatability conditions.&nbsp;<h3>Examples where Equation (1) does not apply&nbsp;</h3>The following paragraphs give two examples where neither the standard deviation nor the standard deviation of the mean can be directly applied without further analysis of the data.&nbsp;<h4>Measurements taken in groups&nbsp;</h4>One example is when we have data from internal quality control from a measurement procedure that includes a calibration before analysis each day. We want to calculate the standard uncertainty of the mean value used to set the central line in the QC chart. The data consist of duplicate QC measurements performed on a stable test sample each day over a longer period of time (say, p days), giving a total of 2p observations; that is, p groups of two measurements. Because each pair of duplicate measurements has a single calibration error in common; the duplicates within the data set are not strictly independent and Eq. (1) cannot be directly used for all 2p observations. The uncertainty of the mean can most easily be calculated by taking the standard deviation of the p means for each day and dividing that standard deviation by √p . Analysis of variance can also be useful in similar cases. Similar principles apply to other kinds of grouping, including grouping by operator, instrument etc.&nbsp;<h4>Measurement when the test item or measurement system is not stable over time</h4>Another common example is time dependent data. The time dependence could be due to instrument drift or to actual change in concentration by time. In such cases the error for a given observation is partly random and in part ‘carried over’ from the previous observation. Again the errors affecting each observation are not independent because some part of the error is common to successive observations; Eq. (1) can not be used and more complex statistical techniques, that allow for correlation, must be used to process the data.&nbsp;For further guidance on the treatment of correlated data in uncertainty evaluation, see Eurolab Technical Report 1/2006: Guide to the Evaluation of Measurement Uncertainty for Quantitative Test Results, Appendix A.5

Using repeated measurements to improve the standard uncertainty

Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 27th July 2026? Check out new documents from the field of spectroscopy/spectrometry and related techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">LabRulezGCMS</a> libraries.</blockquote>This week we bring you application notes by Agilent Technologies, Shimadzu and Thermo Fisher Scientific!<h3>1. Agilent Technologies: High-Precision Determination of Phosphorus and Potassium in Fertilizers by ICP-OES</h3>Accurate nutrient analysis of fertilizers using an <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=5800">Agilent 5800 ICP-OES</a> and standard bracketing<ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_fertilizers_standard_bracketing_5800_icp_oes_5994_9311en_agilent_83cbca87fd.pdf">Full PDF for download</a>&nbsp;</li></ul>Accurate characterization of fertilizer nutrient content is critical for optimizing plant growth, maximizing yield, and ensuring sustainable agricultural practices. Fertilizers must comply with strict regulatory specifications, particularly for declared NPK (nitrogen–phosphorus–potassium) ratios, which define the relative nutrient content supplied to crops. Even small deviations from the specified ratio can impact plant yield, regulatory compliance, customer confidence in the product, as well as its commercial value.&nbsp;Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES) is a well-established technique for multi-element analysis of complex samples, so is ideally suited to meet the precision and accuracy requirements of fertilizer testing.1,2 However, applications that require very tight tolerances, such as NPK verification, benefit from enhanced calibration approaches as even small deviations from reported values can have large financial implications for the manufacturer.Using Agilent ICP-OES instruments, standard bracketing calibration based on a standard–sample–standard measurement sequence, minimizes the impact of sample-to-sample variability and matrix effects.3,4 This approach further improves analytical precision and accuracy compared to conventional external calibration, making it a particularly valuable method for analyzing fertilizers with tightly controlled specifications.&nbsp;In this study, an Agilent 5800 Vertical Dual View (VDV) ICP-OES, equipped with an Agilent SPS 4 autosampler and controlled using Agilent ICP Expert Pro software,5 was used to determine P and K concentrations and corresponding NPK ratios in a standard reference material (SRM) and two commercially available fertilizers. The standard bracketing method was adapted from ISO methods 11494 and 114956,7 and adjusted for fertilizer analysis. The performance of the method, when combined with real-time data processing tools, was evaluated for accuracy and precision.<h4>Experimental&nbsp;</h4><h5>Instrumentation&nbsp;</h5>The <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=5800">Agilent 5800 VDV ICP-OES </a>was configured with the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=SPS+4+autosampler">Agilent SPS 4 autosampler</a>, which provided automated sample delivery to the instrument (Figure 1). The 5800 ICP-OES was equipped with an Agilent SeaSpray nebulizer, double-pass cyclonic spray chamber, and one-piece VDV torch with a 1.8 mm internal diameter (ID) injector. All components were controlled by Agilent ICP Expert Pro* software. Instrument operating parameters are listed in Table 1.<h4>Conclusion&nbsp;</h4>This study demonstrates the effectiveness of the Agilent 5800 VDV ICP-OES standard bracketing method for high-precision determination of phosphorus and potassium in fertilizers. The method delivered excellent performance, with relative standard deviations below 0.1% and excellent agreement with expected NPK values, with recoveries ranging from 99 to 102%. The combination of gravimetrically prepared standards, internal standard correction, and bracketing calibration minimizes analytical variability and ensures reliable results for fertilizer quality control.&nbsp;In addition, Agilent ICP Expert Pro software streamlines analysis through real-time calculations and automated quality control tools, improving laboratory efficiency and reducing the risk of reporting errors. This approach provides a robust and practical solution for high throughput fertilizer testing laboratories, enabling precise NPK verification that strengthens regulatory compliance, reduces the risk of mislabeling, and supports accurate product pricing.<h3>2. Shimadzu: Multifaceted Evaluation of Frozen Tempura Batter Coating Focusing on Food Texture</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_00987_en_f919b540e7.pdf">Full PDF for download</a></li></ul>The “deliciousness” of foods consists of multiple factors, including taste, smell, and visual appeal. However, texture, sometimes called “mouthfeel,” is also one extremely important factor. Mouthfeel refers to the physical sensations experienced when food is placed in the mouth or chewed, and is expressed by various onomatopoeic words such as “crisp” and “chewy.” Among these, the packaging of some foods uses onomatopoeic terms to emphasize the appeal of their distinctive textures, and this has become an important “selling point” for consumers when deciding which product to select.&nbsp;In the development of food products, the method of evaluating texture has become a key point. Sensory methods have long been used, but because sensory evaluations depend on the human senses, they are easily influenced by differences between individuals conducting the evaluation and their physical condition.Thus, the difficulty in ensuring repeatability is an issue. As an additional issue, technical training for the panelists who conduct evaluations also requires time and labor. To compensate for these problems, evaluation methods based on measurement of physical properties with instruments may be used. This approach eliminatesthe human error that had been a problem with sensory evaluations, enabling objective evaluations.&nbsp;Food texture is also complexly influenced by the interactions of various factors, such as the ingredients contained in the food, their amounts, and the cooking method. Since differences in these factors may appear in the structure and surface condition of foods, observation and measurement of the internalstructure and surface condition of foods make it possible to analyze and understand the factors that contribute to texture, allowing more efficient food product development from the physical viewpoint. This article introduces an example of an analysis of the differencesin texture that occur due to differences in the heating method from the aspects of evaluation of physical properties and structural and surface observation, using frozen tempura asthe testsample.<h4>Experiment&nbsp;</h4>In this experiment, four instruments were used for evaluation of mechanical properties and structural and surface observation. Table 1 shows the names of the instruments, the purpose of the experiment, and the corresponding sectionsin this article. The test samples used here were commercially-available frozen tempura, which features “moistness” when prepared by microwave oven cooking and “crispness” after microwave oven + oven cooking. The “Moist” type is prepared by heating for 1 min in a microwave oven, and the “Crisp” type is prepared by additional heating in an oven after microwave heating. Since the heating time in the oven is adjusted depending on the sample size required by each instrument, the specific sample preparation procedure and the flow of the tests will be described in the sections concerning each instrument.<h5>Evaluation of Coating Surface Roughness by Laser Microscope&nbsp;</h5>The laser microscope was used in high-magnification measurements of the roughness of the sample surface and color observation (color images). It is possible to grasp the differences in the batter coatings of the “Moist” and “Crisp” types from changes in roughness and also changes in color. Fig. 11 shows the appearance of the OLS5500 laser microscope used here. In this instrument, optical resolution is enhanced by using a singlewavelength 405 nm laser beam, and topographical information can be acquired by reflective confocal laser microscopy. Color images of the same field can also be obtained by using a white LED.In this experiment, the samples were prepared by the following procedure in order to observe the same areas of the “Moist” and “Crisp” samples. First, the entire kabocha tempura was heated for 1 min in the microwave oven, after which part of the sample was cut off and observed on the stage (Fig. 12). Following this, the observed sample was heated in the oven and placed on the stage again, and the “Crisp” sample was observed (Fig. 13). To observe the shape of a wide area of the sample, an alignment (“tile-stitching”) function was used. The image acquisition condition was the ultra-high speed mode using a 20x objective lens.<h4>Conclusion&nbsp;</h4>A sensory evaluation and evaluation of physical properties using a texture analyzer, and structural observations from the macro to the micro level using an X-ray CT, laser microscope, and SEM were conducted for frozen tempura with different food textures depending on the heating conditions. The impression of the food texture, or “mouthfeel,” obtained in the sensory evaluation was quantified in the form of physical property values by using the texture analyzer, and the factors that formed the grounds for those numerical values were then evaluated based on the results of various types of observation. As a result, it was suggested that differences in food texture correspond to changes in the food structure and oil content.&nbsp;In this experiment, different samples were examined with four types of instruments. However, if physical property tests can be carried out with the samples as-is after observation of the same areas, a more direct and high accuracy analysis is considered to be possible. Moreover, in this experiment, the food texture was changed by using different heating methods, but in cases where the ingredients (flour, oil) or the deep-frying method is changed, there is a possibility that different factors from those in this study may contribute to the texture. As demonstrated in this experiment, although “food texture” is often grasped sensorily, as suggested by the term “mouthfeel,” this property can be visualized scientifically in terms of the structure and physical properties of the food and the condition of the oil content by combining multifaceted evaluations using multiple instruments. This technique is expected to become an effective approach for reproducing and controlling the target texture in food product development and quality design.<h3>3. Thermo Fisher Scientific: Bauxite analysis with Niton XRF analyzers</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/bauxite_analysis_with_niton_xrf_analyzers_an1795_en_93b319a76e.pdf">Full PDF for download</a></li></ul>Globally, bauxite is the primary source of aluminum (Al) ore and anchors a major industry in many countries, including China, Australia, and Brazil. As such, grading Al concentration is of paramount interest in the mine as is the need to determine concentrations of penalty elements. The desired goal is to conduct all the analysis in a way that maximizes productivity.&nbsp;<h4>Application&nbsp;</h4>Analysis of aluminum (Al), silicon (Si), and iron (Fe) presents unique challenges. Accurate analysis of all three is critical for ore grading and understanding their influence on the processing and production of the primary metal of interest. Relying on lab-analysis only in bauxite mining operation often results in costly time delays and reduced productivity while waiting hour if not days and weeks for the results.&nbsp;With the ruggedized, dust- and splash-proof <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1997">Thermo Scientific™ Niton™ XL3t GOLDD+ XRL Analyzer</a>, near lab-quality analysis of Al, Si and Fe can be generated on sites, enabling quick decisions in at remote mines. Indeed, the Niton XL3t GOLDD+ analyzer provides rapid and accurate elemental analyses of bauxite ore enabling to map chemical concentrations in realtime, identify excavation hotspots and detect penalty elements.&nbsp;<h4>Handheld XRF analyzer&nbsp;</h4>Thermo Scientific Niton Handheld XRF analyzers, including the Niton XL3 GOLDD+ analyzer, easily analyze elements from magnesium (Mg) to uranium (U) to fill all exploration and mining needs. These instruments make it easy to perform trend analysis by averaging readings in real-time or by downloading results later to a PC. They deliver fast, accurate elemental analysis for intensive metals exploration and production whether base metals, precious metals, or even rare earth elements.<h4>Comments&nbsp;</h4>The correlation coefficients and repeatability data for the key elements in bauxite analysis demonstrate the excellent accuracy and precision of the handheld Niton XL3 950 GOLDD+ analyzer, indicating that the Niton XL3 GOLDD+ instrument is ideal for fast mine or field analysis. The instant chemical information it provides allows the user to make critical decisions with minimal downtime, keeping projects running and productive. Additionally, they provide information that minimizes the expense and time of shipping samples for analysis and increases savings. The Thermo Scientific Niton XRF analyzer is a great addition to any process in the life of the mine.

News from LabRulezICPMS Library - Week 31, 2026

Article

Application

Academy

Science and research

Since its establishment in 2011, CEITEC has quickly developed into a cutting-edge infrastructure for research which performs highly alongside the best institutes in Europe. Among the main priorities of CEITEC are the promotion of a motivating and dynamic international scientific environment, the provision of state-of-the-art research infrastructure, and the policy of open communication and equal opportunities.

CEITEC

Eurachem is a European network promoting international traceability of chemical measurements and good analytical practice. It provides expert guidance, supports method validation, uncertainty evaluation, proficiency testing, and facilitates discussion on technical and policy issues in analytical quality.

Eurachem

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Thermo Scientific FlashSmart Elemental Analyzer CHNS/O

The Thermo Scientific™ FlashSmart™ Elemental Analyzer (EA), based on the modified Dumas Method, is a flexible solution that expands your CHNS/O analysis with over 20 configurations in one system.

<h3>Lead the way in elemental analysis with a single instrument handling all applications.</h3>You and your team can solve more laboratory challenges, improve workflow and minimize downtime. The Thermo Scientific™ FlashSmart™ Elemental Analyzer (EA), based on the modified Dumas Method, is a flexible solution that expands your CHNS/O analysis with over 20 configurations in one system. Powerful software supports automated and precise reports, making everything easier for you and your team.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Flash_Smart_Elemental_Analyzer_CHNS_O_2_efeac51a98.jpg" alt="Thermo Scientific™ FlashSmart™ Elemental Analyzer CHNS/O" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Flash_Smart_Elemental_Analyzer_CHNS_O_2_efeac51a98.jpg 245w," sizes="100vw" width="1424" height="888"><h3>Why choose the FlashSmart EA?</h3><h4>The confident choice</h4><ul><li>Precise and reliable system that delivers accurate results</li><li>Easy maintenance</li><li>Easy to use for reduced need for staff training</li><li>Modern design combines simple user input with dedicated software features</li><li>Better return on investment as the system is modular and grows with your analytical requirements</li></ul><h4>Simple</h4><ul><li>Gas chromatographic method for real-time view of the analytical process and pathway: anytime, anywhere</li><li>Streamlined sample preparation without the need for dangerous chemicals as Kjeldahl Method</li><li>Complete EA software for effortless operation</li></ul><h4>Modular</h4><ul><li>Over 20 configurations in one instrument: no need for software upgrade</li><li>Up to two autosamplers on the same analyzer</li><li>Higher sample throughput and automation with the Thermo Scientific™ MultiValve Control (MVC) Module, without manual intervention</li><li>Operates with helium and argon as carrier gas</li></ul><h4>Automated</h4><ul><li>Unattended operation of the FlashSmart EA: analyses can run 24/7 for complete results anytime, anywhere</li><li>Dedicated Thermo Scientific™ EagerSmart™ Data</li><li>Handling Software controlling all analytical parameters, Thermo Scientific™ OxyTune™ Function, an autosampler and the MVC Module</li><li>Lower cost per analysis and greater productivity</li></ul><h4>Accurate</h4><ul><li>Certified and uncompromised precision and accuracy for a wide range of applications, from research to routine analysis</li><li>Compliance with most recognized EA Official Methods: AOAC, AOCS, AACC, ASTM, ASBC, ISO, EN, CEN, EPA, IFFO</li><li>OEA CookBook with thousands of determinations and methods for optimal results</li></ul><h4>Robust</h4><ul><li>Robust, specially designed features that you can rely on for decades</li><li>GC separation column operating for years without the need for replacement: it is not a consumable</li><li>Long term investment for your laboratory, which guarantees reliability and accuracy of analysis</li></ul><h3>Access more applications: become the reference laboratory in your field</h3>No matter which direction you take, your lab and equipment will be able to adapt to support any strategy. Flexible systems enable you to react to the new, whilst delivering accurate and reproducible results. With the FlashSmart EA your lab can easily handle varying sample types, obtain from 1 to 5 element determinations and achieve maximum sample throughput.<h4>CHNS/O Analyzer Configuration</h4><ul><li>Perform 5 elements analysis with TCD</li><li>Organic Chemistry: organo-metallic compounds, polymers, plastic, synthetic rubbers, fibers, explosives, catalysts, textiles, pesticides, detergents, and fluorine-compounds.</li><li>Petro-chemistry &amp; Energy: Coals, cokes, crude oils, alternative fuels, petroleum derivates, lubricants, oil additives, and graphite.</li><li>Environmental: Soils, sediments, and rocks, composts, wastes, sewage/sludge, pesticides, water solution, waste water, particulates in air by filters, particulates in water by filters, and woods.</li><li>Material Characterization: Battery, glue/resins, papers, rubbers, cement, ceramics, carbon/glass fibers, tires, pigments and dyes, refractory materials, building materials, inorganic materials, metals, textile fibers, and wood powders.</li></ul><h3>Performance that takes you further</h3>With powerful yet easy operation, your team can process more samples every day. When you need to analyze more elements, you can adapt the FlashSmart EA on-site to your applications or add a second reactor to unlock more capabilities.<h4>Instantly connect</h4><ul><li>Thermal Conductivity Detector (TCD)</li></ul><h4>Sample introduction modularity</h4><ul><li>Up to two Thermo Scientific™ MAS Plus Autosamplers</li><li>One MAS Plus Autosampler and one manual liquid sampler</li></ul><h4>Carrier gas options</h4><ul><li>Helium</li><li>Argon option for lower cost and regular supply</li><li>Switch to nitrogen or argon when in Stand-By Mode</li></ul><h4>Gas chromatographic method: real-time analysis</h4><ul><li>Proper quantification of the five elements</li><li>“Open window” function giving information on what is happening inside the analyzer in real-time</li><li>Straightforward and intuitive workflow without valves</li><li>No absorption or desorption of gases needed</li></ul><figure class="image"><img style="aspect-ratio:1482/903;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Flash_Smart_Elemental_Analyzer_CHNS_O_3_ae03e912c7.jpg" alt="Thermo Scientific™ FlashSmart™ Elemental Analyzer CHNS/O" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Flash_Smart_Elemental_Analyzer_CHNS_O_3_ae03e912c7.jpg 245w," sizes="100vw" width="1482" height="903"></figure><h3>Software automates consistent sampling and reports</h3><h4>Software</h4>The Thermo Scientific EagerSmart Data Handling Software allows you to leave the FlashSmart EA unattended to get completed analysis, with full, user-friendly reports. The software controls all analytical parameters, flows, autosamplers and detectors, by suggesting the most favourable analytical conditions for your samples.<ul><li>Automated transfer of the sample weight from the balance to the software</li><li>Automated evaluation of Heat Values (Gross and Net Heat Values) for fuels and alternative fuels</li><li>CO2 Emission Trade for environmental control</li><li>Different Protein Factors for food and animal feed</li><li>Inserting of the Humidity value for solid samples and of the Density for liquid samples</li><li>Automated Minimal Formula determination for pharmaceutical or fine chemicals applications</li><li>Automated evaluation of C/N, C/H and C/S ratio</li><li>Automated data transfer to Microsoft Excel, LIMS and others</li></ul><h4>Automated functions</h4><ul><li>Auto-Start</li><li>Auto-Ready</li><li>Auto-Stand-By</li><li>Auto-Off</li><li>Auto Leak Test</li></ul><h4>Unique and dedicated OxyTune function</h4>The Thermo Scientific OxyTune Function automatically evaluates the oxygen needed for combustion, according to the weight and nature of your sample.<h4>MultiValve Control Module: future-proof lab with more throughput and less costs</h4>By switching the analysis from the left channel to the right one (or viceversa), the MVC Module increases your analysis throughput. When the system is not in use overnight, on weekends, or for a prolonged period of time you can also reduce helium consumption and overall cost of analysis by switching from helium to nitrogen or argon.<ul><li>Fully automated and software controlled</li><li>No need to change hardware or software configuration</li><li>Optional feature for extended lab throughput</li><li>Easy to add</li></ul>

Thermo Scientific™ GS Omni Analyzer

Thermo Scientific GS Omni uses PGNAA to provide continuous, calibration-free elemental analysis of process streams. Designed for demanding industrial slurry applications.

The Thermo Scientific™ GS Omni Light Element Analyzer provides robust, accurate elemental analysis for multiple process streams, delivering real-time information for the optimization of slurry beneficiation processes such as froth flotation. Utilizing industry-leading Prompt Gamma Neutron Activation Analysis (PGNAA) technology, it measures both heavy and light elements, crucially covering the Z&lt;20 elements – calcium and lighter – that are less well-suited to X-Ray Fluorescence (XRF) analysis. Together, Thermo Scientific PGNAA and XRF analyzers allow customers to measure the broadest possible range of elements.Since the PGNAA signal is unaffected by particle size, ore matrix or inter-element interference, the GS Omni requires no recalibration as the ore changes, enabling robust measurement with minimal cost and ongoing effort. Easily configured for between two and eight process streams, it provides data that you can confidently rely on. Use the GS Omni to control contaminant elements, improve product quality, increase recovery, and lower production costs.The GS Omni offers near metallurgical quality analysis for up to eight process streams, depending on concentration, elements of interest, required cycle analysis time, plant layout, and process control considerations.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_GS_Omni_Analyzer_927ddc6cd4.jpg" alt="Thermo Scientific™ GS Omni Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_GS_Omni_Analyzer_927ddc6cd4.jpg 237w," sizes="100vw" width="650" height="427"><h3>🔑 Key features include:</h3><ul><li>Capability to measure light elements such as calcium, chlorine, sulfur, aluminum, silicon, magnesium, and sodium, for industrially relevant analysis over an extended range of elements relative to XRF.</li><li>Unaffected by matrix effects and particle size – unlike XRF – for robust measurements in the face of process changes and ore variability with no requirement for recalibration.</li><li>Scintillation detectors eliminate the need for cooling apparatus, enabling simpler set-up and operation with no requirement for chillers or special environmental control.</li><li>Modular multiplexer, for expansion from 2 to 8 streams.</li><li>Holding tank and sample recirculation through the measurement zone provide deaeration, which along with multiple passes through PGNAA source delivers more accurate measurement for slurry streams.</li><li>Factory calibrated for slurry applications with only infrequent site checks required, enabling minimal manual input and low maintenance.</li></ul>

Thermo Scientific™ FLASH 2000 CHNS/O Analyzers

The FLASH 2000 CHNS/O analyzer combines simplicity, precision, and low operating costs. Offers up to 12 configurations for a broad range of applications across science and industry.

<div><div>Decades of experience combined with our constant innovation in developing organic elemental analyzers (OEAs) contributed to the design of the Thermo Scientific™ FLASH 2000 CHNS/O Analyzers. This system delivers the ultimate in simplicity, precision, and cost effectiveness for any laboratory requiring the quantification of carbon, hydrogen, nitrogen, sulfur, and oxygen.Providing a reliable, high-speed, accurate 24/7 analytical solution to a range of industries, this series of flexible, configurable analyzers uses a globally recognized technique endorsed by official organizations worldwide.</div><div><h3>An Elemental Analysis Solution for a Range of Industries</h3>With an extraordinary range of applications, the modular design of the FLASH 2000 Series OEAs enables 12 configurations tailored to the fields of application they serve.<ul><li>Organic or inorganic chemistry and pharmaceuticals</li><li>Petrochemistry and energy</li><li>Environmental analysis</li><li>Material characterization</li><li>Agronomy and marine science</li><li>Food industry</li><li>Human and animal samples</li><li>Isotope analysis</li><li>Academic</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_FLASH_2000_CHNS_O_Analyzers_3139f1b44b.jpg" alt="Thermo Scientific™ FLASH 2000 CHNS/O Analyzers" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_FLASH_2000_CHNS_O_Analyzers_3139f1b44b.jpg 149w," sizes="100vw" width="650" height="680"><h3>Gain Cost Efficiency and Improve Productivity</h3>The simplicity of the OEA method combined with unparalleled data reproducibility and truly quantitative results are the essence of the sophisticated package of benefits offered by the FLASH 2000 Series OEA instruments.<ul><li>Wide analytical range, enabling extensive applications</li><li>Versatility and modularity, ensuring that performance meets users' requirements no matter how often those requirements change</li><li>Accuracy and precision due to the integrated mass flow controller, which enables high stability to deliver precise, accurate results in all sample types and concentrations</li><li>Ease of use as a result of the unique automated functions, reducing the demands on operators</li><li>Simplified operation with Thermo Scientific™ Eager Xperience™ software, which minimizes user involvement in set-up</li><li>Compatibility and automation no matter how high your throughput requirement, with a range of autosamplers that ensures efficient analysis</li><li>Comprehensive and user-friendly software, a useful and powerful tool tailored for every lab requirement</li><li>Ground-breaking OEA CookBook (4th edition), which provides a wealth of analysis tips to get optimal results every time</li></ul></div></div>

Products from category Elemental Analyzers - page 1

Related content

How to Kill Staphylococcus Aureus: A New Insight into Viruses That Can Defeat Bacteria

News from LabRulezICPMS Library - Week 31, 2026

Using repeated measurements to improve the standard uncertainty