<p><strong>Scientists from CEITEC Brno University of Technology led by Markéta Kaiser have achieved a globally unique breakthrough in coral research. Using the live microCT method, they were able, for the first time ever, to observe the growth of living marine corals in real time and reveal the processes behind the formation of their calcium carbonate skeletons, which had previously remained hidden beneath the surface. The results of the international study, published in the prestigious journal </strong><i><strong>Science Advances</strong></i><strong>, show how corals grow, regenerate, and respond to stress and competing organisms.</strong></p><p>The <a target="_blank" rel="noopener noreferrer" href="https://www.science.org/doi/10.1126/sciadv.aee3183"><strong>study</strong></a><strong> </strong>was carried out through a collaboration between researchers from Brno, Vienna, and several other international institutions. A key role was played by the <i><strong>X-ray Micro and Nano Computed Tomography Laboratory (CTLAB)</strong></i><strong> at CEITEC BUT</strong>, where all the crucial data and three-dimensional coral models were produced. CEITEC also shares both the first and corresponding authorship of the study.</p><p><i>“Thanks to live microCT, we were able, for the first time, to observe what happens beneath the surface of a coral skeleton,”</i> explains Markéta <strong>Kaiser from CTLAB at CEITEC BUT</strong>. <i>“For example, we witnessed situations where a coral, after being attacked by algae, completely halted its normal growth and began building a protective wall around the threatened area. Once the danger had passed, it was able to resume its original growth pattern.”</i></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_540e183e84.jpeg" alt="CEITEC BUT/Jakub Rozboud: Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life: Markéta Kaiser, CTLAB CEITEC at CEITEC BUT." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_540e183e84.jpeg 235w," sizes="100vw" width="1600" height="1067"></p><p>The scientists successfully captured coral<strong> growth both vertically and horizontally, the formation of protective barriers against competing organisms, and regeneration mechanisms following damage</strong>.</p><p>The research was exceptionally demanding from a technological standpoint. The team had to develop a<strong> special system</strong> that enabled living corals to be safely scanned <strong>directly in seawater</strong>. The coral colonies regularly traveled by train from Vienna to Brno for measurements and, after several hours, were transported back to professional aquarium systems in Vienna.</p><p><i>“At first, it seemed like a somewhat crazy idea. No one knew whether living corals could withstand repeated scanning,</i>” says Kaiser. <i>“Gradually, however, we found that they survived, continued to grow, and provided us with unique data.”</i></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_2_fcbb29a4f6.jpeg" alt="CEITEC BUT/Jakub Rozboud: Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life: Markéta Kaiser is placing a coral sample into CT for scanning." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_2_fcbb29a4f6.jpeg 235w," sizes="100vw" width="1600" height="1067"></p><p>The original concept for the project came from developmental biologist<strong> Igor Adameyko of the Medical University of Vienna</strong>, who proposed combining marine biology with advanced imaging technologies more commonly used in engineering and technical fields.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_3_8c5f376f41.jpeg" alt="CEITEC BUT/Markéta Kaiser: Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life: Corals CT - 1." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_3_8c5f376f41.jpeg 228w," sizes="100vw" width="1600" height="1096"></p><p>The findings of the Brno researchers have already attracted the attention of experts in <strong>Okinawa, Japan</strong>, who specialize in coral reef research. They plan to use the live microCT method to study the effects of light, photosynthesis, and environmental changes on coral growth.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_4_445c1cc3b7.jpeg" alt="CEITEC BUT/Markéta Kaiser: Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life:Corals CT - 2." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_4_445c1cc3b7.jpeg 245w," sizes="100vw" width="1600" height="988"></p><p>According to the researchers, the project demonstrates the importance of interdisciplinary collaboration between engineering and biological sciences. The research could contribute not only to the study and conservation of coral reefs, but also to fields such as paleontology and materials science.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_5_514ee9c974.jpg" alt="CEITEC BUT/Markéta Kaiser: Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life: Corals CT - 3." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Zivi_korali_jezdili_vlakem_z_Vidne_do_Brna_Vedci_diky_nim_odhalili_jejich_tajny_zivot_5_514ee9c974.jpg 143w," sizes="100vw" width="1600" height="1750"></p><blockquote><h4><strong>Original Article</strong></h4><h4><a target="_blank" rel="noopener noreferrer" href="https://www.science.org/doi/10.1126/sciadv.aee3183"><strong>Coral growth, retraction, defense, and regenerative strategies revealed by live microCT</strong></a></h4><p>Karina Araslanova, Marketa Kaiser, Anton Fetisov, Diana Gavrik, Tomas Zikmund, Daniel Abed-Navandi, Karel Katovský, Jozef Kaiser, Igor Adameyko</p><p><i><strong>Sci. Adv., 2026, 12, eaee3183</strong></i></p><p><a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1126/sciadv.aee3183"><span>https://doi.org/10.1126/sciadv.aee3183</span></a></p><h6>licenced under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/"><strong>CC-BY 4.0</strong></a></h6></blockquote><h4><strong>Abstract</strong></h4><p>Understanding how corals build and remodel their skeletons is key to explaining reef resilience, yet most insights come from static imaging. Using longitudinal live microCT, we tracked the same coral colonies over weeks to months at micrometer resolution. Coral skeleton formation is not a uniform accretion process but a dynamic integration of multiple programs, including vertical and horizontal patterned growth, previously undescribed defensive wall-building against competitors, exploratory edge behavior with reversible expansions and retractions, and skeletal regeneration favoring rapid, imprecise yet effective matrix expansion. Time-resolved imaging links colony-scale growth to microscale events, showing that all modes depend on balances between fusion of skeletal microparticles and layered matrix deposition, guided by tissue prepatterning. Beyond corals, this framework generalizes to studying skeletal dynamics across diverse biomineralizing organisms.</p>

Live Corals Traveled by Train from Vienna to Brno. Scientists Uncovered Their Secret Life 

<p><strong>This study investigates the antioxidant and anti-inflammatory effects of (−)-epicatechin in an in vitro model of metabolic dysfunction-associated steatotic liver disease (MASLD). Lipid peroxidation, inflammatory, and profibrotic markers were assessed alongside ATR-FTIR spectroscopy to evaluate whether spectral changes reflect disease progression and treatment response.</strong></p><p>Epicatechin reduced lipid peroxidation products, TNF-α, and TGF-β1 in a concentration-dependent manner, with stronger protective effects observed during pretreatment. ATR-FTIR spectral changes closely correlated with biochemical markers, demonstrating its potential as a rapid, non-destructive tool for monitoring oxidative stress, inflammation, and fibrosis in MASLD research.</p><blockquote><h4><strong>The original article</strong></h4><h4><a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsomega.5c09978"><strong>ATR-FTIR Assessment of the Antioxidant and Anti-Inflammatory Effects of (−)-Epicatechin in MASLD</strong></a></h4><p>Marija Hefer, Nikolina Filipović, Stjepan Šarić, Nela Malatesti, Ana Petrović, Elvira Kovač-Andrić*, and Martina Smolić*</p><p>ACS Omega 2026, 11, 23, 33333–33344</p><p><a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1021/acsomega.5c09978">https://doi.org/10.1021/acsomega.5c09978</a></p><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/"><strong>CC-BY 4.0</strong></a></h6></blockquote><p><strong>Selected sections from the article follow. Formats and hyperlinks were adapted from the original.</strong></p><div><p>Metabolic dysfunction-associated steatotic liver disease (MASLD) represents one of the most prevalent chronic liver disorders. Due to its predisposition to progress toward metabolic dysfunction-associated steatohepatitis (MASH), fibrosis, cirrhosis, and even hepatocellular carcinoma (HCC), MASLD has become a significant global health burden and a major challenge for healthcare systems. <a href="javascript:void(0);">(1−4)</a></p><p>The majority of patients with MASLD or MASH are obese and frequently present with additional metabolic comorbidities, most commonly insulin resistance, type 2 diabetes mellitus, and dyslipidemia. <a href="javascript:void(0);">(5−7)</a> Furthermore, most conditions associated with MASLD and MASH are characterized by lipid metabolism impairment, with elevated levels of oxidative stress. Impaired lipid metabolism, together with prolonged oxidative stress, promotes hepatocellular lipotoxicity and mitochondrial dysfunction. These alterations affect the antioxidant defense system and increase reactive oxygen species (ROS) generation, thereby contributing to the onset of MASLD and its progression to MASH, along with more advanced liver diseases. <a href="javascript:void(0);">(8,9)</a></p><p>One of the main results of oxidative stress is lipid peroxidation, in which ROS attack (poly)unsaturated fatty acids within membrane lipids. This initiates a series of structural and functional alterations, where the formation of conjugated dienes (CDs) reflects early double-bond rearrangements in fatty acyl chains, while lipid hydroperoxides (LOOHs) represent key propagation-phase products that destabilize cell membranes and increase oxidative injury. <a href="javascript:void(0);">(10,11)</a> Therefore, determining LOOH and CD levels, along with their overall LOOH/CD ratio, might be useful for determining the lipid peroxidation dynamics and the progression of MASLD.</p><p>Along with oxidative damage to the cell structures, inflammation is also a key regulator of MASLD progression. In this context, tumor necrosis factor-α (TNF-α) is suspected to play a central role as its levels are found to increase alongside MASLD to MASH progression. <a href="javascript:void(0);">(12−14)</a> It has also been found that ROS and TNF-α are closely interconnected, where elevated TNF-α levels could serve as an indicator of oxidative cellular damage and enhanced lipid peroxidation. <a href="javascript:void(0);">(15−17)</a> Often, one of the results of MASLD progression is the development of liver fibrosis, which is usually mediated by transforming growth factor beta 1 (TGF-β<sub>1</sub>) as its levels are frequently elevated in MASH and contribute to the worsening of hepatic steatosis. <a href="javascript:void(0);">(18)</a> <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsomega.5c09978#fig1">Figure 1</a> summarizes the pathways associated with MASLD to MASH progression, with emphasis on lipid peroxidation (CDs, LOOHs) and inflammatory/fibrogenic signaling (TNF-α, TGF-β<sub>1</sub>).</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ACS_Omega_2026_11_23_33333_33344_Figure_1_Schematic_representation_of_lipid_peroxidation_and_its_role_in_MASLD_progression_e6a8e05d3e.jpeg" alt="ACS Omega 2026, 11, 23, 33333–33344: Figure 1. Schematic representation of lipid peroxidation and its role in MASLD progression. Lipid accumulation in MASLD leads to the release of free radicals and ROS, which attack (poly)unsaturated fatty acids within membrane lipids, leading to lipid peroxidation, inflammation (via TNF-α), and fibrotic changes (via TGF-β1), thereby contributing to the transition from MASLD to MASH and further progression to cirrhosis and HCC. In lipid peroxidation, reactive radicals (R·) subtract the hydrogen from the (poly)unsaturated lipid, thereby resulting in the formation of a lipid radical, which undergoes rearrangements to form a CD. The lipid radical then reacts with molecular oxygen to form an unstable lipid peroxyl radical, which further subtracts a hydrogen from another (poly)unsaturated lipid, thereby resulting in the formation of a LOOH. The subtraction of hydrogen from the (poly)unsaturated lipid also results in the formation of a lipid radical, thereby perpetuating the chain reaction. The figure was created with Servier Medical Art (https://smart.servier.com/) and MarvinSketch (ChemAxon, https://chemaxon.com/marvin)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ACS_Omega_2026_11_23_33333_33344_Figure_1_Schematic_representation_of_lipid_peroxidation_and_its_role_in_MASLD_progression_e6a8e05d3e.jpeg 216w," sizes="100vw" width="1834" height="1327"></p><p>However, the exact role of different lipid peroxidation indicators and their contribution to MASLD progression toward MASH have not yet been fully elucidated, with the number of studies addressing this issue remaining limited. Given these limitations in research, attention has increasingly turned toward dietary antioxidants, particularly polyphenols or mixtures of polyphenol-rich plant extracts, as potential modulators of oxidative stress and lipid peroxidation in hepatic steatosis. <a href="javascript:void(0);">(19−23)</a></p><p>Among available polyphenols, we selected (−)-epicatechin (EC) because of its strong antioxidant and radical scavenging capacity, with its documented effects on inflammatory signaling. <a href="javascript:void(0);">(24−26)</a> One study even found that the antifibrotic properties of EC were comparable to those of silymarin, with EC showing even stronger reducing effects on malondialdehyde (MDA) formation in vivo. <a href="javascript:void(0);">(27)</a> Since MDA is a secondary product of LOOH breakdown, <a href="javascript:void(0);">(28)</a> these results could link EC’s potential antifibrotic properties to its ability to attenuate lipid peroxidation, thereby potentially mitigating the progression of MASLD to MASH. Unlike more extensively studied compounds such as epigallocatechin gallate, <a href="javascript:void(0);">(29,30)</a> EC has been less investigated in the context of MASLD, providing an opportunity to explore a novel candidate. At the same time, the growing use of advanced spectroscopic techniques offers new opportunities to monitor biochemical alterations in cells and tissues.</p><p>Attenuated total reflection-Fourier transform infrared (ATR-FTIR) spectroscopy recently emerged as a promising tool for monitoring such changes. The application of ATR-FTIR spectroscopy and similar techniques for steatosis and lipid quantification, along with determining the lipid peroxidation extent, has been introduced, especially in the context of hepatic steatosis. Determining the intensity of C═O vibrational stretching at ∼1740 cm<sup>–1</sup> (triacylglycerols, cholesteryl esters, lipid oxides), as this type of bond usually occurs in lipid peroxidation, could also be valuable for determining the overall extent of steatosis. <a href="javascript:void(0);">(31−33)</a> Along with lipid peroxidation extent, determining the degree of unsaturation in MASLD models is crucial for understanding the changes in cellular components as the degree of unsaturation is often found to decrease due to steatotic changes in cells and tissues. (Poly)unsaturated fatty acids contribute to membrane fluidity and are essential for maintaining membrane integrity and signaling, while their depletion leads to increased membrane rigidity and impaired cellular function. <a href="javascript:void(0);">(34,35)</a> Given their high susceptibility to peroxidation, a reduction in their levels could indicate either an adaptive response to oxidative stress or a disruption of lipid homeostasis. Therefore, correlating the degree of unsaturation (∼3010 cm<sup>–1</sup> for ═C–H) and the intensity of carbonyl stretching (∼1740 cm<sup>–1</sup> for C═O) with the LOOH/CD ratio and cytokines, TNF-α and TGF-β<sub>1</sub>, could be valuable for the noninvasive monitoring of disease progression.</p><h4><strong>Methods</strong></h4><h5><strong>Experimental Design</strong></h5><p>Two experimental models were introduced for the experiments: EC pretreatment and EC Posttreatment models. In both models, the untreated cells (UT) group was used as a negative (vehicle) control group, while the sodium oleate-treated group (OA) was used as a positive control group, with EC (control) being the highest concentration of EC used as a control for the tested compound. In the Pretreatment model, the cells were pretreated with 10, 30, and 50 μM EC for 4 h, followed by a 24 h posttreatment with 1.5 mM sodium oleate. In the Posttreatment model, the cells were treated with 1.5 mM sodium oleate for 12 h, followed by the addition of the same concentrations of EC in the presence of 0.75 mM sodium oleate. All of the experimental groups were labeled as EC50+OA, EC30+OA, and EC10+OA, according to the concentration used in the experiments. EC concentrations of 10, 30, and 50 μM were chosen based on our previous MTS assay and Oil Red O staining results, where we tested 10–100 μM EC to evaluate its effect on MASLD in the Pretreatment model. <a href="javascript:void(0);">(42)</a> As it was proven effective in the Pretreatment model, the Posttreatment model was added to evaluate whether EC could also mitigate oxidative and inflammatory/fibrotic changes once steatosis was already established. Another important consideration was to assess the potential cytotoxicity of the concentrations used, as EC and other polyphenols are often consumed as dietary supplements with poorly regulated dosages. As these cytotoxic effects are often subtle and overlooked in conventional biochemical assays, combining FTIR spectral analysis with complementary assays could provide a more comprehensive assessment of potential cytotoxicity.</p><h5><strong>ATR-FTIR Assessment of Lipid Peroxidation</strong></h5><p>ATR-FTIR spectroscopy was used to determine the extent of lipid peroxidation and steatosis. The lipid samples were dissolved in chloroform and normalized to a lipid concentration of 20 mg/mL. After the evaporation of the solvent, the ATR-FTIR spectra were recorded using an <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=Cary+630"><strong>Agilent Cary 630 FTIR spectrophotometer</strong></a> (Agilent Technologies, Santa Clara, CA, USA), at the Faculty of Biotechnology and Drug Development at the University of Rijeka. All ATR-FTIR spectra were processed using the automatic least-squares baseline correction algorithm implemented in <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=MicroLab+Expert"><strong>Agilent MicroLab Expert v.10.5 software</strong></a> (4000–650 cm<sup>–1</sup>; clean scans: 4; threshold: 0.002; background scans: 2; sample scans: 100; resolution: 16 cm<sup>–1</sup>; apodization: HappGenzel; phase correct: Mertz; method gain: 221). Spectra of pure chloroform were recorded under identical conditions and subtracted from sample spectra to remove any residual solvent contributions. Chloroform was recorded to be excluded in the background, and the data were collected in the spectral range 3200–1600 cm<sup>–1</sup> on an ATR device. To ensure comparability between samples, the spectra were normalized against the asymmetric CH<sub>2</sub> stretching vibration of lipid acyl chains (2925–2922 cm<sup>–1</sup>), which was used as an internal reference band due to its relative stability across treatments and minimal alteration during lipid peroxidation. Baseline correction was applied prior to normalization to minimize background variability. Relative intensities of lipid peroxidation-associated bands (C═O stretching at 1744–1735 cm<sup>–1</sup> and ═C–H stretching at 3010 cm<sup>–1</sup>) were then expressed as a ratio to the CH<sub>2</sub> reference peak, allowing quantitative comparison of the lipid peroxidation extent between experimental groups. The data were presented as percent relative intensities (%<i>I</i><sub>rel</sub>).</p><h4><strong>Results and Discussion</strong></h4><h5><strong>ATR-FTIR Spectroscopy for the Assessment of Lipid Peroxidation and Steatosis Extent</strong></h5><p>To evaluate the overall steatosis and lipid peroxidation extent in HepG2 cells, ATR-FTIR spectroscopy was used. <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsomega.5c09978#fig5">Figure 5</a> shows the 3200–1600 cm<sup>–1</sup> spectral region, including the key C═O (1744–1735 cm<sup>–1</sup>) and ═C–H (3010 cm<sup>–1</sup>) stretching bands, which correlated with the biochemical parameters measured in this study. The increased intensity of the C═O band in sodium oleate-treated groups corresponds to the accumulation of oxidized lipid species derived from peroxidation of (poly)unsaturated fatty acids. On the other hand, a decrease in the ═C–H stretching band near 3010 cm<sup>–1</sup> indicates a progressive depletion of double bonds which undergo rearrangement to form CDs or further transformations associated with lipid peroxidation.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ACS_Omega_2026_11_23_33333_33344_Figure_5_ATR_FTIR_spectra_of_control_groups_aabfabbdc1.jpeg" alt="ACS Omega 2026, 11, 23, 33333–33344: Figure 5. ATR-FTIR spectra of control groups: UT (blue) and EC (control) (purple); along with experimental groups: OA (yellow), EC50+OA (red), EC30+OA (orange), and EC10+OA (brown) in the wavenumber range 3200–1600 cm–1 for the (a) EC Pretreatment Model and (b) EC Posttreatment Model." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ACS_Omega_2026_11_23_33333_33344_Figure_5_ATR_FTIR_spectra_of_control_groups_aabfabbdc1.jpeg 193w," sizes="100vw" width="1572" height="1272"></p><p>All experimental groups show similar FTIR profiles in the lipid regions; however, to determine the overall extent of lipid peroxidation and steatosis, the relative intensities of ═C–H stretching of unsaturated lipids (3010 cm<sup>–1</sup>) and C═O stretching of esters (1744–1735 cm<sup>–1</sup>) were measured according to the baseline and normalized according to asymmetric CH<sub>2</sub> stretching of lipid chains (2925–2922 cm<sup>–1</sup>) (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsomega.5c09978#fig6">Figure 6</a>). This approach was chosen as the greatest changes were noticed among the given intensities of the peaks in all groups.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ACS_Omega_2026_11_23_33333_33344_Figure_6_Percent_relative_intensities_e921d53b57.jpeg" alt="ACS Omega 2026, 11, 23, 33333–33344: Figure 6. Percent relative intensities (%Irel) of ═C–H stretching (unsaturated lipids) and C═O stretching of esters for the (a) EC Pretreatment Model and (b) EC Posttreatment Model. The results are presented as mean values of %Irel ± SD." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ACS_Omega_2026_11_23_33333_33344_Figure_6_Percent_relative_intensities_e921d53b57.jpeg 149w," sizes="100vw" width="1000" height="1044"></p><p>Also, as indicated in the literature, the increase in intensities of C═O stretching and a decrease in intensities of ═C–H stretching are mostly associated with an increase in the lipid peroxidation extent. <a href="javascript:void(0);">(33,50)</a> Furthermore, a decrease in ═C–H stretching corresponds to a decrease in the (poly)unsaturated fatty acid content, which is often noted in MASLD/MASH models. <a href="javascript:void(0);">(51,52)</a></p><h4><strong>Conclusion</strong></h4><p>In a sodium oleate-induced hepatic steatosis model, EC showed a concentration-dependent effect on the overall radical scavenging ability of HepG2 cells. However, when EC was given as a posttreatment, these results were not achievable. EC also reduced propagation-phase lipid peroxidation by reducing relative LOOH levels in both models, lowering the LOOH/CD ratio (except for the EC50+OA pretreatment group), and effectively decreasing sodium oleate-induced increases in TNF-α and TGF-β<sub>1</sub> concentrations. ATR-FTIR results were consistent with changes in lipid (per)oxidation and reflected the overall antioxidant and anti-inflammatory effects of EC observed through biochemical assays. Compared with biochemical assays, ATR-FTIR spectroscopy has several advantages, including rapid and nondestructive analysis that requires minimal sample preparation. Considering that it can simultaneously capture multiple molecular changes, this represents a reliable approach for accurate and complementary insights into lipid peroxidation and redox alterations in MASLD. However, it is important to correlate ATR-FTIR spectral changes with biochemical assays to further strengthen its interpretation.</p></div>

ATR-FTIR Assessment of the Antioxidant and Anti-Inflammatory Effects of (−)-Epicatechin in MASLD

<p><strong>In the week from July 6, the following webinars await you in the field of atomic and molecular spectroscopy and spectrometry</strong></p><blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4><p><strong>👉 Search and filter in the largest global database</strong> with over <strong>5 500 GC, LC, MS and spectroscopy webinars</strong>.</p></blockquote><h5><strong>1. Thermo Fisher Scientific: Lunch and Learn Tips and Tricks Series: Trace Elemental Analysis (ICP-OES &amp; ICP-MS)</strong></h5><ul><li>Tu, 7.7.2026 12:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/5977">Registration</a></li></ul><p>Learn practical tips to optimize ICP-OES and ICP-MS performance, improve data quality, streamline troubleshooting and maintenance, and enhance sample preparation for more efficient elemental analysis.</p><h5><strong>2. SelectScience: Expanding the 4D-STEM Toolbox for Advanced Materials Characterization</strong></h5><ul><li>Tu, 7.7.2026 15:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6318">Registration</a></li></ul><p>Explore how Timepix4 detector technology advances 4D-STEM workflows, enabling high-resolution imaging, data-driven acquisition, and new opportunities in electron microscopy.</p><h5><strong>3. Anton Paar: Microwave Digestion: The Foundation of Accurate Trace Metal Analysis</strong></h5><ul><li>We, 8.7.2026 09:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6321">Registration</a></li></ul><p>Build robust workflows for trace metal analysis. Learn how microwave digestion ensures fast, contamination-free, and complete sample preparation across complex food matrices.</p><h5><strong>4. Wiley: From liquids to solids: expand what your UV-Vis-NIR Spectrometer can do</strong></h5><ul><li>We, 8.7.2026 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6367">Registration</a></li></ul><p>Discover how the Agilent Cary UV-Vis-NIR spectrometer, together with Specac accessories, enables reliable analysis of liquids, powders, films, pellets, and highly scattering solid samples.</p><h5><strong>5. SelectScience: The next generation ICP-MS designed to wow trace element analysts</strong></h5><ul><li>We, 8.7.2026 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6320">Registration</a></li></ul><p>Upgrade your trace-element analysis. Discover how the new Agilent 9500 ICP-MS eliminates interferences and simplifies method development for complex matrices.</p><h5><strong>6. LECO: Dry Matter and Ash Determination in Wastewater and Sewage Sludge</strong></h5><ul><li>Th, 9.7.2026 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6324">Registration</a></li></ul><p>Optimize wastewater analysis. Learn how automated thermogravimetric analysis (TGA) replaces manual drying and ashing steps to determine dry matter and ash in sewage sludge.</p><h5><strong>7. Waters Corporation: Cracking the Code on Nitrogen Methods</strong></h5><ul><li>Th, 9.7.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6327">Registration</a></li></ul><p>Learn the fundamentals of nitrogen analysis for wastewater testing. Explore analytical methods, QA/QC, sample handling, compliance reporting, and troubleshooting for accurate environmental monitoring.</p><h5><strong>8. Agilent Technologies: ICP Expert 7.8: Booming ICP-OES Software Innovation</strong></h5><ul><li>Th, 9.7.2026 20:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6368">Registration</a></li></ul><p>Discover what's new in ICP Expert™ 7.8 and how the latest software innovations can improve data quality, simplify routine operation, and increase day-to-day laboratory efficiency.</p>

Webinars LabRulezICPMS Week 28/2026

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Since its establishment in 2011, CEITEC has quickly developed into a cutting-edge infrastructure for research which performs highly alongside the best institutes in Europe. Among the main priorities of CEITEC are the promotion of a motivating and dynamic international scientific environment, the provision of state-of-the-art research infrastructure, and the policy of open communication and equal opportunities.

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Thermo Scientific Nicolet Summit LITE FTIR Spectrometer

Compact FTIR spectrometer for routine material identification, QA/QC laboratories, and education. Features LightDrive optics, OMNIC Paradigm software, and easy operation.

<p><strong>The Thermo Scientific™ Nicolet™ Summit™ LITE FTIR Spectrometer is a compact and cost-effective Fourier Transform Infrared (FTIR) spectrometer designed for routine material identification, quality control, incoming goods inspection, and educational laboratories. Combining the proven LightDrive™ Optical Engine with intuitive OMNIC™ Paradigm Software, the system enables users to identify, verify, and characterize materials quickly and confidently.</strong></p><p>Engineered with the same core optical technology used in higher-end Nicolet systems, the Summit LITE delivers reliable <strong>performance, simplified operation, and low ownership costs</strong>. Its compact footprint makes it an ideal solution for multi-user laboratories, QA/QC environments, and teaching facilities where space, efficiency, and ease of use are important.</p><h3><strong>Key Features</strong></h3><ul><li><strong>LightDrive™ Optical Engine</strong> for stable, reliable FTIR performance</li><li><strong>5-year warranty </strong>on the interferometer, laser, and infrared source</li><li><strong>OMNIC™ Paradigm Software </strong>with intuitive dashboard interface</li><li><strong>Smart Background technology</strong> for automatic background collection</li><li><strong>LightBar LED status indicator</strong> with visual pass/fail feedback</li><li>Customizable workflows for routine analytical procedures</li><li><strong>Cloud-enabled connectivity </strong>through OMNIC™ Anywhere</li><li><strong>Built-in spectral library</strong> searching and material identification tools</li><li>Compact, laboratory-friendly footprint</li><li>Optional Everest™ ATR accessory with monolithic diamond crystal</li><li>Designed for QA/QC, teaching, and routine analytical laboratories</li><li>Fast implementation with extensive online help and training resources</li></ul><h3><strong>Software Features</strong></h3><p><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2456"><strong>OMNIC™ Paradigm Software</strong></a> simplifies FTIR operation for both experienced spectroscopists and routine users.</p><h4><strong>Key software capabilities include:</strong></h4><ul><li>Spectral acquisition and processing</li><li>Multi-component searching</li><li>Spectral library creation and management</li><li>Workflow automation</li><li>Automatic background collection</li><li>Remote data access through cloud connectivity</li><li>Secure data handling and compliance-ready workflows</li><li>Support for regulated laboratory environments</li></ul><h3><strong>Technical Specifications</strong></h3><ul><li><strong>Beam Splitter:</strong> KBr/Ge mid-infrared optimized</li><li><strong>Optical Components:</strong> LightDrive Optical Engine including source, laser, interferometer, and detector</li><li><strong>Detector Type:</strong> Lithium tantalate (LiTaO₃) detector</li><li><strong>Dimensions (D × W × H):</strong> 32 × 34 × 24 cm (12.7 × 13.3 × 9.6 in.)</li><li><strong>Applications:</strong> Education, Polymers &amp; Plastics, QA/QC, Pharmaceuticals, Forensics, Environmental Analysis</li><li><strong>Compatible Accessories:</strong> Everest™ Diamond ATR, iD™ Accessories (including iD7 ATR), and hundreds of commercially available accessories</li><li><strong>Source Type:</strong> Single-point IR source with non-migrating hotspot for enhanced data reproducibility</li><li><strong>Spectral Range:</strong> 8000–350 cm⁻¹</li><li><strong>Spectral Resolution:</strong> Better than 0.6 cm⁻¹</li><li><strong>Voltage:</strong> 110/240 V</li><li><strong>Warranty:</strong> 5-year warranty on the interferometer, laser, and infrared source</li></ul><h3><strong>Typical Applications</strong></h3><h4><strong>Pharmaceutical Analysis</strong></h4><ul><li>Raw material identification</li><li>Incoming goods inspection</li><li>Verification of pharmaceutical ingredients</li><li>Contaminant identification</li></ul><h4><strong>Polymer Analysis</strong></h4><ul><li>Polymer identification</li><li>Additive verification</li><li>Material degradation studies</li><li>Packaging material quality control</li></ul><h4><strong>Education</strong></h4><ul><li>FTIR teaching laboratories</li><li>Functional group identification</li><li>Student training and practical exercises</li></ul><h4><strong>Battery Materials</strong></h4><ul><li>Electrolyte characterization</li><li>Material verification</li><li>Quality control of battery components</li></ul><h4><strong>Gemology and Mineral Analysis</strong></h4><ul><li>Gemstone identification</li><li>Mineral composition analysis</li><li>Authentication of natural materials</li></ul><h4><strong>Automotive Materials</strong></h4><ul><li>Polymer and composite characterization</li><li>Interior material verification</li><li>Fuel additive analysis</li><li>Failure investigations</li></ul><h4><strong>Lubricants and Oils</strong></h4><ul><li>Condition monitoring</li><li>Lubricant formulation verification</li><li>Contamination detection</li><li>Predictive maintenance programs</li></ul><h3><strong>Benefits</strong></h3><ul><li>Affordable entry into FTIR spectroscopy</li><li>Easy operation for non-expert users</li><li>Compact design for space-limited laboratories</li><li>Reliable daily performance for routine testing</li><li>Low maintenance requirements</li><li>Fast material identification and verification</li><li>Suitable for both educational and industrial laboratories</li></ul><p>The Nicolet Summit LITE FTIR Spectrometer delivers the essential capabilities required for routine FTIR analysis while maintaining the simplicity, reliability, and affordability expected from the Thermo Scientific Nicolet product family.</p>

Thermo Scientific Nicolet Summit X FTIR Spectrometer

High-performance Thermo Scientific Nicolet Summit X FTIR Spectrometer for QA/QC, research, and regulated laboratories. Features LightDrive optics, a DTGS detector, OMNIC Paradigm software, and advanced workflows.

<p><strong>The Thermo Scientific™ Nicolet™ Summit™ X FTIR Spectrometer is a powerful and versatile Fourier Transform Infrared (FTIR) spectrometer designed for laboratories that require enhanced performance, regulatory readiness, and advanced analytical capabilities. Combining the proven LightDrive™ Optical Engine with OMNIC™ Paradigm Software, the Summit X delivers fast, reliable material identification and characterization while simplifying routine and complex analytical workflows.</strong></p><p>Ideal for both single-user and multi-user laboratories, the Summit X provides an excellent balance of performance, flexibility, and ease of use. Its compact footprint, robust construction, and advanced software environment make it suitable for quality control, research, teaching, and regulated laboratory environments. The system is designed to help laboratories improve productivity, streamline workflows, and maintain confidence in analytical results.</p><h3><strong>Key Features</strong></h3><ul><li>LightDrive™ Optical Engine for exceptional FTIR performance and long-term stability</li><li>10-year warranty on the interferometer, laser, and infrared source</li><li>High-performance DTGS detector</li><li>OMNIC™ Paradigm Software with intuitive dashboard interface</li><li>Smart Background technology for automatic background collection</li><li>LightBar LED status indicator with visual pass/fail feedback</li><li>Pharmacopeia-ready workflows for regulated environments</li><li>Drag-and-drop workflow creation and automation</li><li>Cloud-enabled connectivity through Thermo Fisher Connect and OMNIC™ Anywhere</li><li>Multi-component spectral searching and library management</li><li>Optional touchscreen interface for simplified QA/QC operation</li><li>Optional Everest™ ATR accessory with monolithic diamond crystal</li><li>Compact design suitable for busy laboratory environments</li><li>Designed for routine QA/QC, analytical services, and research applications</li><li>5,000 included reference spectra for rapid compound identification</li></ul><h3><strong>Software Features</strong></h3><p><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2456"><strong>OMNIC™ Paradigm Software </strong></a>provides a modern, workflow-oriented platform that simplifies FTIR analysis for both experienced spectroscopists and routine users.</p><h4><strong>Key software capabilities include:</strong></h4><ul><li>Spectral acquisition and processing</li><li>Multi-component searching</li><li>Spectral library creation and management</li><li>Automated workflow generation</li><li>Drag-and-drop workflow editor</li><li>Smart Background automatic background measurement</li><li>One-click spectral, correlation, and multi-component searching</li><li>Cloud-based data access and collaboration</li><li>AI-assisted spectral interpretation through OMNIC™ Anywhere</li><li>Dashboard-based instrument monitoring and data management</li><li>Support for data integrity and compliance workflows</li></ul><h3><strong>Technical Specifications</strong></h3><ul><li><strong>Beam Splitter:</strong> KBr/Ge mid-infrared optimized</li><li><strong>Optical Components:</strong> LightDrive™ Optical Engine including source, laser, interferometer, and detector</li><li><strong>Detector Type:</strong> Fast-recovery deuterated triglycine sulfate (DTGS) detector</li><li><strong>Dimensions (D × W × H):</strong> 32 × 34 × 24 cm (12.7 × 13.3 × 9.6 in.)</li><li><strong>Applications:</strong> Quality Control (QA/QC), Forensics, Polymers &amp; Plastics, Pharmaceuticals, Environmental Analysis, Education, Geology and Gemstone Analysis</li><li><strong>Compatible Accessories:</strong> Everest™ Diamond ATR, iD™ Accessories (including iD7 ATR), and hundreds of commercially available accessories</li><li><strong>Source Type:</strong> Single-point IR source with non-migrating hotspot for enhanced data reproducibility</li><li><strong>Spectral Range:</strong> 8000–350 cm⁻¹</li><li><strong>Spectral Resolution:</strong> Better than 0.6 cm⁻¹</li><li><strong>Electrical Requirements:</strong> 100/240 V, 47/63 Hz, 110 W</li><li><strong>Warranty:</strong> 10 years on the interferometer, laser, and infrared source</li></ul><h3><strong>Typical Applications</strong></h3><h4><strong>Pharmaceutical Analysis</strong></h4><ul><li>Raw material verification</li><li>Incoming goods inspection</li><li>Pharmacopeial compliance workflows</li><li>Contaminant identification</li><li>At-line manufacturing support</li></ul><h4><strong>Polymer Analysis</strong></h4><ul><li>Polymer identification</li><li>Additive verification</li><li>Material degradation studies</li><li>Packaging material quality control</li><li>Composite material characterization</li></ul><h4><strong>Education and Academic Research</strong></h4><ul><li>FTIR teaching laboratories</li><li>Functional group identification</li><li>Student training and practical exercises</li><li>Research applications</li></ul><h4><strong>Battery Materials and Components</strong></h4><ul><li>Electrolyte characterization</li><li>Material verification</li><li>Quality control of battery components</li><li>Monitoring material changes affecting battery performance and safety</li></ul><h4><strong>Gemology and Mineral Analysis</strong></h4><ul><li>Gemstone identification</li><li>Mineral composition analysis</li><li>Authentication of treated and untreated gemstones</li></ul><h4><strong>Automotive Materials</strong></h4><ul><li>Polymer and composite characterization</li><li>Interior material verification</li><li>Fuel additive analysis</li><li>Material development and failure investigations</li></ul><h4><strong>Lubricants and Oils</strong></h4><ul><li>Lubricant condition monitoring</li><li>Formulation verification</li><li>Contamination detection</li><li>Predictive maintenance programs</li></ul><h3><strong>Benefits</strong></h3><ul><li>Enhanced performance for demanding QA/QC laboratories</li><li>Long-term reliability supported by a 10-year optical system warranty</li><li>Intuitive software that reduces training requirements</li><li>Streamlined workflows that improve laboratory productivity</li><li>Ready for regulated and compliance-driven environments</li><li>Flexible platform for both routine analysis and advanced applications</li><li>Cloud-enabled collaboration and remote data access</li><li>Compact design with a small laboratory footprint</li></ul><p>The Nicolet Summit X FTIR Spectrometer combines high-performance optics, advanced software, and regulatory-ready workflows in a compact platform designed to meet the needs of modern analytical laboratories. Whether used for quality control, materials characterization, research, or regulated testing, the Summit X delivers the performance, reliability, and productivity expected from the Thermo Scientific™ Nicolet™ product family.</p>

Thermo Scientific Nicolet Summit PRO FTIR Spectrometer

High-performance Thermo Scientific Nicolet Summit PRO FTIR spectrometer for demanding QA/QC, regulated, and research laboratories. Features touchscreen operation, high spectral resolution, and OMNIC Paradigm software.

<p><strong>The Thermo Scientific™ Nicolet™ Summit™ PRO FTIR Spectrometer is the most advanced model in the Nicolet Summit family, combining high-performance optics, superior spectral resolution, and an integrated touchscreen interface in a compact and versatile platform. Designed for demanding QA/QC laboratories, analytical service laboratories, regulated environments, and research applications, the Summit PRO delivers fast, reliable material identification and characterization while simplifying routine and advanced workflows.</strong></p><p>Powered by the proven LightDrive™ Optical Engine and OMNIC™ Paradigm Software, the Summit PRO offers outstanding performance, intuitive operation, and advanced compliance capabilities. Its integrated touchscreen interface and built-in workflow tools help laboratories improve productivity, streamline data acquisition, and maintain confidence in analytical results.</p><h3><strong>Key Features</strong></h3><ul><li>LightDrive™ Optical Engine for exceptional FTIR performance and long-term stability</li><li>High-resolution performance with spectral resolution better than 0.45 cm⁻¹</li><li>Thermoelectrically cooled (TEC) DTGS detector for maximum detector response linearity</li><li>10-year warranty on the interferometer, laser, and infrared source</li><li>Integrated touchscreen interface for simplified QA/QC workflows</li><li>OMNIC™ Paradigm Software with touchscreen, operator, and desktop operating modes</li><li>Smart Background technology for automatic background collection</li><li>LightBar LED status indicator with visual pass/fail feedback</li><li>Pharmacopeia-ready workflows for regulated environments</li><li>Drag-and-drop workflow creation and automation</li><li>Cloud-enabled connectivity through Thermo Fisher Connect and OMNIC™ Anywhere</li><li>AI-assisted spectral interpretation through OMNIC™ Anywhere</li><li>Multi-component spectral searching and library management</li><li>Everest™ ATR accessory with monolithic diamond crystal available</li><li>5,000 included reference spectra for rapid compound identification</li><li>Compact footprint suitable for both routine and research laboratories</li></ul><h3><strong>Software Features</strong></h3><p><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2456"><strong>OMNIC™ Paradigm Software</strong></a><strong> </strong>provides a modern, workflow-oriented platform that simplifies FTIR analysis for both experienced spectroscopists and routine users.</p><h4><strong>Key software capabilities include:</strong></h4><ul><li>Spectral acquisition and processing</li><li>Multi-component searching</li><li>Spectral library creation and management</li><li>Automated workflow generation</li><li>Drag-and-drop workflow editor</li><li>Smart Background automatic background measurement</li><li>One-click spectral, correlation, and multi-component searching</li><li>Cloud-based data access and collaboration</li><li>AI-assisted spectral interpretation through OMNIC™ Anywhere</li><li>Dashboard-based instrument monitoring and data management</li><li>Support for data integrity and compliance workflows</li><li>Touchscreen, Operator, and Desktop operating modes</li></ul><h3><strong>Technical Specifications</strong></h3><ul><li><strong>Beam Splitter:</strong> KBr/Ge mid-infrared optimized</li><li><strong>Optical Components:</strong> LightDrive™ Optical Engine including source, laser, interferometer, and detector</li><li><strong>Detector Type:</strong> Thermoelectrically cooled (TEC) DTGS detector for maximum detector response linearity</li><li><strong>Dimensions (D × W × H):</strong>&nbsp;<ul><li><strong>Spectrometer: </strong>32 × 34 × 24 cm (12.7 × 13.3 × 9.6 in.)</li><li><strong>Spectrometer with touchscreen:</strong> 32 × 53 × 43 cm (12.0 × 20.8 × 17.0 in.)</li></ul></li><li><strong>Applications:</strong> Polymers &amp; Plastics, QA/QC, Pharmaceuticals, Education, Forensics, Geology and Gemstone Analysis, Automotive Materials, Environmental Analysis</li><li><strong>Compatible Accessories:</strong> Everest™ Diamond ATR, iD™ Accessories (including iD7 ATR), and hundreds of commercially available accessories</li><li><strong>Source Type:</strong> Single-point IR source with non-migrating hotspot for unmatched data reproducibility</li><li><strong>Spectral Range:</strong> 8000–350 cm⁻¹</li><li><strong>Spectral Resolution:</strong> Better than 0.45 cm⁻¹</li><li><strong>Electrical Requirements:</strong> 100/240 V, 47/63 Hz, 110 W</li><li><strong>Weight:</strong><ul><li><strong>Spectrometer: </strong>10.9 kg (24 lb)</li><li><strong>Spectrometer with touchscreen:</strong> 12.6 kg (29 lb)</li></ul></li><li><strong>Warranty:</strong> 10 years on the interferometer, laser, and infrared source</li></ul><h3><strong>Typical Applications</strong></h3><h4><strong>Pharmaceutical Analysis</strong></h4><ul><li>Raw material verification</li><li>Incoming goods inspection</li><li>Pharmacopeial compliance workflows</li><li>Contaminant identification</li><li>At-line manufacturing support</li></ul><h4><strong>Polymer Analysis</strong></h4><ul><li>Polymer identification</li><li>Additive verification</li><li>Material degradation studies</li><li>Packaging material quality control</li><li>Composite material characterization</li></ul><h4><strong>Education and Academic Research</strong></h4><ul><li>FTIR teaching laboratories</li><li>Functional group identification</li><li>Student training and practical exercises</li><li>Research applications</li></ul><h4><strong>Battery Materials and Components</strong></h4><ul><li>Electrolyte characterization</li><li>Material verification</li><li>Quality control of battery components</li><li>Monitoring material changes affecting battery performance and safety</li></ul><h4><strong>Gemology and Mineral Analysis</strong></h4><ul><li>Gemstone identification</li><li>Mineral composition analysis</li><li>Authentication of treated and untreated gemstones</li></ul><h4><strong>Automotive Materials</strong></h4><ul><li>Polymer and composite characterization</li><li>Interior material verification</li><li>Fuel additive analysis</li><li>Material development and failure investigations</li></ul><h4><strong>Lubricants and Oils</strong></h4><ul><li>Lubricant condition monitoring</li><li>Formulation verification</li><li>Contamination detection</li><li>Predictive maintenance programs</li></ul><h3><strong>Benefits</strong></h3><ul><li>Highest-performance model in the Nicolet Summit product family</li><li>Superior spectral resolution for advanced analytical applications</li><li>Integrated touchscreen interface for streamlined operation</li><li>Long-term reliability backed by a 10-year optical system warranty</li><li>Advanced compliance and data integrity capabilities</li><li>Flexible platform for QA/QC, regulated laboratories, and research</li><li>Cloud-enabled collaboration and remote data access</li><li>Compact design with a small laboratory footprint</li></ul><p>The <strong>Thermo Scientific™ Nicolet™ Summit™ PRO FTIR Spectrometer </strong>combines high-resolution optics, advanced software, touchscreen operation, and regulatory-ready workflows in a powerful platform designed for modern analytical laboratories. Whether used for quality control, materials characterization, compliance testing, or research, the Summit PRO delivers the highest level of performance available within the Nicolet Summit FTIR family.</p>

Thermo Scientific Nicolet Summit OA FTIR Spectrometer

Dedicated FTIR analyzer for oils, liquids, syrups, and pastes. Features an integrated ZnSe HATR accessory, OMNIC Paradigm software, and rapid qualitative and quantitative analysis.

<p><strong>The Thermo Scientific™ Nicolet™ Summit™ OA FTIR Spectrometer is a dedicated analyzer designed for rapid characterization of oils, liquids, syrups, and viscous samples. Featuring an integrated zinc selenide (ZnSe) horizontal attenuated total reflectance (HATR) accessory, the system provides a constant and reproducible pathlength, making it ideal for both qualitative and quantitative analysis. Its rugged, spill-resistant design and compact footprint make it particularly well suited for QA/QC laboratories and routine industrial testing.</strong></p><p>Powered by the proven LightDrive™ Optical Engine and intuitive OMNIC™ Paradigm Software, the Summit OA delivers reliable performance, simplified workflows, and rapid results. Built-in workflow automation, multivariate analysis capabilities, and seamless cloud connectivity help laboratories improve efficiency while maintaining confidence in analytical data.</p><h3><strong>Key Features</strong></h3><ul><li>Dedicated FTIR analyzer for oils, liquids, syrups, and pastes</li><li>Integrated 40° ZnSe HATR accessory for rapid qualitative and quantitative analysis</li><li>Enhanced sensitivity through multi-reflection HATR technology</li><li>Up to 8× higher absorbance than conventional single-bounce ATR accessories</li><li>LightDrive™ Optical Engine for reliable long-term performance</li><li>10-year warranty on the interferometer, laser, and infrared source</li><li>OMNIC™ Paradigm Software with customizable workflows</li><li>Built-in Windows® 10 computer</li><li>LightBar LED status indicator</li><li>Integration with Thermo Scientific™ TQ Analyst™ software</li><li>User-replaceable ZnSe HATR crystal plate</li><li>Compact, rugged, and spill-resistant design</li></ul><h3><strong>Software Features</strong></h3><p><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2456"><strong>OMNIC™ Paradigm Software </strong></a>provides a flexible and intuitive environment for routine testing, material identification, and quantitative analysis.</p><h4><strong>Key software capabilities include:</strong></h4><ul><li>Spectral acquisition and processing</li><li>Workflow creation and automation</li><li>Visual workflow builder with drag-and-drop functionality</li><li>Spectral comparison and optimization tools</li><li>Multi-component searching</li><li>Cloud-based data access and collaboration</li><li>Integration with Thermo Fisher Connect</li><li>Support for qualitative and quantitative workflows</li><li>Integration with TQ Analyst™ for multivariate analysis</li><li>Packaged workflows for routine operator use</li></ul><h3><strong>Multiple Operating Modes</strong></h3><p><strong>Touchscreen Mode</strong></p><ul><li>Simple click-and-go operation</li><li>Apply → Measure → Clean workflow</li></ul><p><strong>Desktop Mode</strong></p><ul><li>Workflow creation</li><li>Spectral processing and comparison</li><li>Instrument optimization and method development</li></ul><p><strong>Operator Mode</strong></p><ul><li>Password-protected application packages</li><li>Controlled access to predefined workflows, calibrations, and diagnostics</li></ul><h3><strong>Technical Specifications</strong></h3><ul><li><strong>Beam Splitter:</strong> KBr/Ge mid-infrared optimized</li><li><strong>Optical Components:</strong> LightDrive™ Optical Engine including source, laser, interferometer, and detector</li><li><strong>Detector Type:</strong> Fast-recovery deuterated triglycine sulfate (DTGS) detector</li><li><strong>Sampling Accessory:</strong> Integrated zinc selenide (ZnSe) Horizontal ATR (HATR)</li><li><strong>Dimensions (D × W × H):</strong> 32 × 34 × 24 cm (12.7 × 13.3 × 9.6 in.)</li><li><strong>Applications:</strong> Oils, Liquids, Syrups and Pastes, QA/QC, Food &amp; Beverage, Automotive</li><li><strong>Source Type:</strong> Single-point IR source with non-migrating hotspot for unmatched data reproducibility</li><li><strong>Spectral Range:</strong> 6000–650 cm⁻¹</li><li><strong>Electrical Requirements:</strong> 100/240 V, 47/63 Hz, 110 W</li><li><strong>Weight:</strong> 12.6 kg (27.8 lb)</li><li><strong>Warranty:</strong> 10 years on the interferometer, laser, and infrared source</li></ul><h3><strong>Typical Applications</strong></h3><h4><strong>Lubricants and Oils</strong></h4><ul><li>In-service lubricant analysis</li><li>Oil condition monitoring</li><li>Compliance with ASTM D7418, ASTM E2412, and JOAP methods</li><li>Predictive maintenance programs</li></ul><h4><strong>Food and Beverage</strong></h4><ul><li>Edible oil quality control</li><li>Verification of frying oil condition</li><li>Consistency monitoring of food products</li><li>Syrup and beverage analysis</li></ul><h4><strong>Fuels and Biofuels</strong></h4><ul><li>Determination of FAME content in diesel fuel</li><li>Compliance with ASTM D7371</li><li>Biodiesel blend quality control</li></ul><h4><strong>Quality Control and Manufacturing</strong></h4><ul><li>Incoming goods inspection</li><li>Product verification</li><li>Batch-to-batch consistency monitoring</li><li>Routine QA/QC testing</li></ul><h4><strong>Customer-Specific Applications</strong></h4><ul><li>Qualitative material identification</li><li>Quantitative analysis</li><li>Process monitoring</li><li>Custom workflow development</li></ul><h3><strong>Benefits</strong></h3><ul><li>Optimized specifically for liquid and viscous samples</li><li>High sensitivity through integrated multi-reflection HATR technology</li><li>Reduced risk of sample spills damaging the instrument</li><li>Fast, reproducible measurements with minimal sample preparation</li><li>Simplified workflows for routine operators</li><li>Rugged design suitable for industrial environments</li><li>Seamless integration of qualitative and quantitative analysis</li><li>Long-term reliability backed by a 10-year optical system warranty</li></ul><p>The Thermo Scientific™ Nicolet™ Summit™ OA FTIR Spectrometer combines dedicated liquid-sample analysis, integrated HATR technology, intuitive software, and proven FTIR performance in a compact platform designed for routine quality control and industrial testing. Whether analyzing lubricants, edible oils, fuels, syrups, or other liquid products, the Summit OA delivers fast, reliable, and reproducible results.</p>

Products from category FTIR spectrometers from Thermo Fisher Scientific - page 1

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