Agilent Resolve Raman Spectrometer

Význam tématu

Raman spectroscopy offers rapid, nondestructive molecular analysis with minimal sample preparation. The ability to perform high-resolution measurements in the field expands its utility across pharmaceuticals, agriculture, food safety and defense. Portable systems that deliver laboratory-grade data are critical for real-time decision making in onsite quality control and rapid screening applications.

Cíle a přehled článku

This application note presents the Agilent Resolve handheld Raman spectrometer, emphasizing its advanced optics, rugged design, and proprietary spatially offset Raman spectroscopy (SORS) capability. The goal is to demonstrate how Resolve enables through-barrier, noninvasive analysis in challenging environments and to outline its operational modes, data management options and performance features.

Použitá instrumentace

The core instrumentation described includes:

• Agilent Resolve handheld Raman spectrometer
• 830 nm class 3B laser with SORS optics for fluorescence mitigation
• Rugged handheld housing with gloved operation interface
• Rechargeable lithium-ion battery for up to 4 h continuous use
• Agilent Command Fleet Management software for library creation and remote control

Hlavní výsledky a diskuse

The Resolve system delivers benchtop-quality spectra in a portable form factor. Key findings include:

• High signal-to-noise ratio enabling clear analyte identification even through colored, opaque or multilayer packaging
• SORS Through-Barrier mode for sub-surface measurements without sample removal
• Vial Holder and Surface Scan modes for rapid screening of contained or line-of-sight samples
• Flexible data export in CSV or SPC formats via USB, Wi-Fi or Bluetooth API
• Onboard library matching and user-created reference libraries for instant identification

Discussion highlights the nondestructive nature of the technique, its time savings by eliminating manual sampling and its reproducibility under field conditions.

Přínosy a praktické využití metody

Practical benefits of the Resolve handheld Raman spectrometer include:

• On-site quality control of raw materials and finished products
• Noninvasive screening of vaccines and pharmaceuticals through vials
• Agricultural field analysis for nutritional profiling, variety identification and disease detection
• Food and beverage authentication to detect adulteration and ensure safety
• Enhanced safety and efficiency by avoiding sample destruction and exposure to hazards

Budoucí trendy a možnosti využití

Emerging applications and developments include:

• Integration of advanced chemometric models and AI for quantitative predictions
• Expansion of Bluetooth API usage for real-time spectrum streaming and IoT connectivity
• Broader adoption in environmental monitoring, forensic analysis and industrial process control
• Development of combined Raman/FTIR workflows using complementary handheld instruments

Závěr

The Agilent Resolve handheld Raman spectrometer bridges the gap between laboratory performance and field portability. Its robust design, SORS capability and flexible data handling make it a versatile tool for nondestructive, high-throughput analysis across diverse sectors. Resolve enhances onsite decision making and supports advanced analytical workflows.

Reference

1. Agilent Technologies, Resolve Raman Spectrometer Application Note, August 2025.