Thermo Scientific iCAP RQ ICP-MS

Significance of the topic

ICP-MS is an essential tool for high-sensitivity, multi-element analysis across environmental, clinical, pharmaceutical, food safety, geoscience and industrial fields. The iCAP RQ ICP-MS combines robustness and productivity to meet the demands of modern routine laboratories.

Objectives and overview

This document presents the design, performance and workflow integration of the Thermo Scientific iCAP RQ ICP-MS system. It aims to demonstrate enhanced throughput, ease of use and reliable data quality through advanced hardware and software features.

Methodology and instrumentation

The iCAP RQ employs single quadrupole technology with a QCell collision/reaction cell, He KED mode and optional reactive gases for comprehensive interference removal. Three interchangeable interfaces optimize sensitivity and matrix tolerance. Integrated high-definition plasma imaging and quick-connect sample introduction streamline setup and maintenance.

Used instrumentation

• Thermo Scientific iCAP RQ ICP-MS with single quadrupole and QCell technology
• High-definition plasma monitoring camera and self-aligning sample introduction components
• Three interface options: Robust, High Matrix, High Sensitivity
• Qtegra Intelligent Scientific Data Solution (ISDS) Software with plug-ins for IC/LC, GC, laser ablation and spICP-MS

Key results and discussion

The system achieves sub-ppt detection for light elements like Li and Be in He KED mode and maintains plasma stability with challenging matrices including seawater and 100% organic solvents. Automated workflows, one-click startup and rapid cone changes reduce downtime. Comprehensive interference removal ensures accurate multi-element data.

Benefits and practical applications

• High-throughput routine analysis with minimal maintenance
• Robust performance for environmental, clinical and pharmaceutical compliance (EPA 200.8, USP/ICH Q3D)
• Food safety and speciation analysis via IC/LC/GC coupling
• Material and geoscience studies with laser ablation and advanced interface options
• Nuclear applications requiring high sensitivity and isotope ratio stability

Future trends and potential applications

Advancements may include broader integration of hyphenated techniques, artificial intelligence-driven method optimization, expanded nanoparticle characterization, enhanced isotopic ratio analysis and further automation for continuous, unattended operation.

Conclusion

The iCAP RQ ICP-MS delivers a powerful balance of sensitivity, robustness and usability, addressing the needs of high-throughput laboratories. Its intuitive hardware and software features support consistent, accurate results while minimizing operational overhead.

References

No external references provided.