CRM Chlorides (Cl-) - Aqueous calibration solution ASTASOL® AN907210H

Significance of Topic

Aqueous calibration solutions play a pivotal role in ensuring accurate quantification of analytes in environmental, pharmaceutical and industrial laboratories. Certified reference materials (CRMs) such as ASTASOL® AN907210H provide traceable, stable and homogeneous standards for chloride determination, supporting method validation, instrument calibration and quality assurance across a variety of analytical platforms.

Objectives and Study Overview

This document describes the certification and key properties of ASTASOL® AN907210H, an aqueous chloride calibration solution manufactured by ANALYTIKA®, spol. s r.o. The aim is to deliver a reference material with a well-defined chloride concentration, low impurity levels and full traceability to SI units, suitable for multiple spectrometric and electroanalytical techniques.

Methodology and Instrumentation

• Gravimetric Preparation: Precise weighing of high-purity KCl (99.997 %) in ultrapure water to achieve target concentration and direct SI traceability.
• Argentometric Titration: Verification of chloride concentration and uncertainty assessment (k = 2).
• Ion Chromatography (IC): Quantification of trace anionic impurities (Br–, F–, I–, NO₂–, NO₃–, PO₄³–, SO₄²–) for informational purposes.

Main Results and Discussion

• Certified Concentration: 10 000 ± 20 mg/L Cl⁻ at 20 °C.
• Density: 1.0113 ± 0.0005 g/cm³ at 20 °C, enabling conversion to mass fraction 9 888 ± 30 mg/kg.
• Trace Impurities: All monitored anions are below detection limits (< 0.02–0.05 mg/L), confirming high solution purity.
• Homogeneity and Stability: Demonstrated over five years unopened and 12 months after first opening, when stored at 5–30 °C and used at 20 ± 0.5 °C.

Benefits and Practical Applications

• Versatile Use: Calibration and validation in AAS, AES, ICP-OES, ICP-MS, IC, molecular absorption spectrometry and selected electroanalytical methods.
• Quality Assurance: Direct SI traceability and low uncertainty support robust QA/QC procedures and regulatory compliance.
• User Guidance: Clear instructions on storage, handling and expiration labeling minimize the risk of concentration drift or contamination.

Future Trends and Potential Uses

As analytical demands evolve, CRMs like ASTASOL® AN907210H will remain essential for emerging high-resolution techniques and automated workflows. Future developments may focus on micro-volume standards, multi-analyte solutions and digital certification to streamline laboratory accreditation and data integrity.

Conclusion

ASTASOL® AN907210H offers a rigorously characterized chloride calibration solution with demonstrated homogeneity, stability and SI traceability. Its broad compatibility with spectrometric and electroanalytical techniques makes it a valuable tool for accurate chloride measurement and continuous quality control across diverse analytical environments.

Reference

ANALYTIKA®, spol. s r.o. Certificate for ASTASOL® AN907210H Aqueous Calibration Solution. Version 01, 27.09.2023.