CRM Chlorides (Cl-) - Aqueous calibration solution ASTASOL® AN90721HIC

Importance of Calibration Standards for Chloride Analysis

A reliable chloride calibration solution underpins accurate quantitative measurements in environmental, industrial and clinical laboratories. Certified reference materials with defined uncertainty ensure traceability to SI units and support method validation across a range of instrumental techniques, including atomic spectrometry and ion chromatography.

Objectives and Overview of the Certified Reference Material

The document certifies ASTASOL® AN90721HIC as an aqueous calibration solution for chloride (Cl–). It defines composition, concentration, uncertainty and storage conditions to support consistent analytical results. Key specifications include:

• Certified concentration: 1 000 mg/L ±2 mg/L (k=2) at 20 °C
• Derived mass fraction: 1 001 mg/kg ±3 mg/kg
• Matrix: ultrapure demineralized water (≥18 MΩ·cm, 0.22 μm filtered)
• Starting reagent: KCl, purity 99.997%
• Batch number, production date and shelf life details

Methodology

The solution is prepared gravimetrically to ensure direct traceability to the kilogram. Filtration through a 0.45 μm membrane ultrafilter prevents particulate interference in chromatography. Certified values are verified by argentometric titration, and trace impurity levels are determined by ion chromatography for user information.

Used Instrumentation

• High-precision analytical balance for gravimetric preparation
• Membrane ultrafilter (0.45 μm) for solution clarification
• Standard argentometric titration setup for chloride quantification
• Ion chromatography system for impurity assessment

Key Results and Discussion

The CRM demonstrates high homogeneity and stability throughout its five-year shelf life when stored at 5–30 °C. Density at 20 °C is 0.9994 g/cm³ ±0.0005 g/cm³. Impurity concentrations for Br–, F–, I–, NO₂–, NO₃–, PO₄³– and SO₄²– are below detection limits (<0.02–0.05 mg/L). These characteristics confirm suitability for method validation in diverse analytical platforms.

Benefits and Practical Applications

A standardized chloride solution supports:

• Calibration of AAS, AES, ICP-OES, ICP-MS for trace element analysis
• Validation of ion chromatography methods
• Quality control in environmental, food and industrial testing
• Verification of electroanalytical procedures

Future Trends and Potential Applications

Advances may include multi-analyte calibration solutions, digital certification via blockchain for enhanced traceability, miniaturized on-site standards for field analysis, and automated dispensing systems to reduce human error.

Conclusion

ASTASOL® AN90721HIC provides a rigorously certified chloride standard with documented uncertainty, traceability and robust storage guidelines. Its consistent performance enhances analytical accuracy across a range of techniques and industries.

Reference

Detailed production and characterization procedures are available from the producer’s documentation “Detailed information about the production of aqueous calibration solutions ASTASOL®”.