Determination of sun protection factor in creams using visible near-infrared spectroscopy
Applications | 2018 | MetrohmInstrumentation
Sunscreen products play a critical role in preventing UV induced skin damage and reducing skin cancer risks. Reliable determination of sun protection factor is essential for quality control and regulatory compliance in the cosmetic industry. Rapid non destructive methods that minimize sample preparation and chemical waste help laboratories maintain throughput and sustainability.
The aim of this study was to develop a rapid visible near infrared spectroscopy method to predict the sun protection factor of commercial sunscreen creams. Fourteen samples with SPF values ranging from 10 to 50 were analyzed to establish a calibration model and validate its performance.
Cream samples were applied to the slurry cup and measured in transflection mode over the 400 nm to 2500 nm range. Spectra were pretreated using second derivative and standard normal variate. A Partial Least Squares regression model with four factors was developed to correlate spectral data with reference SPF values.
A high correlation between predicted and reference SPF was achieved (R2 = 0.9932). Calibration and cross validation errors were low (SEC = 1.30, SECV = 2.20). The model effectively distinguishes between SPF levels across the tested range demonstrating the sensitivity of Vis NIR spectral features to sunscreen composition.
The approach can be extended to additional quality parameters such as moisture content or active ingredient concentration. Integration into process analytical technology for inline monitoring and adaptation to broader cosmetic formulations may further enhance production efficiency and compliance.
Visible near infrared spectroscopy on the NIRS DS2500 platform provides a fast accurate and sustainable alternative for sun protection factor determination in creams. The method streamlines quality control workflows and supports the growing demand for efficient analytical solutions in personal care industries.
NIR Spectroscopy
IndustriesOther
ManufacturerMetrohm
Summary
Significance of the Topic
Sunscreen products play a critical role in preventing UV induced skin damage and reducing skin cancer risks. Reliable determination of sun protection factor is essential for quality control and regulatory compliance in the cosmetic industry. Rapid non destructive methods that minimize sample preparation and chemical waste help laboratories maintain throughput and sustainability.
Study Objectives and Overview
The aim of this study was to develop a rapid visible near infrared spectroscopy method to predict the sun protection factor of commercial sunscreen creams. Fourteen samples with SPF values ranging from 10 to 50 were analyzed to establish a calibration model and validate its performance.
Instrumentation
- NIRS DS2500 Analyzer
- DS2500 Slurry Cup
- 1 mm Gold diffuse reflector
- Vision Air 2.0 Complete software
Methodology
Cream samples were applied to the slurry cup and measured in transflection mode over the 400 nm to 2500 nm range. Spectra were pretreated using second derivative and standard normal variate. A Partial Least Squares regression model with four factors was developed to correlate spectral data with reference SPF values.
Main Results and Discussion
A high correlation between predicted and reference SPF was achieved (R2 = 0.9932). Calibration and cross validation errors were low (SEC = 1.30, SECV = 2.20). The model effectively distinguishes between SPF levels across the tested range demonstrating the sensitivity of Vis NIR spectral features to sunscreen composition.
Benefits and Practical Applications
- Non destructive analysis requiring no sample preparation
- Rapid measurement duration under 30 seconds per sample
- Minimal chemical waste and simple accessory cleaning
- Suitable for routine quality control in cosmetic manufacturing
Future Trends and Potential Applications
The approach can be extended to additional quality parameters such as moisture content or active ingredient concentration. Integration into process analytical technology for inline monitoring and adaptation to broader cosmetic formulations may further enhance production efficiency and compliance.
Conclusion
Visible near infrared spectroscopy on the NIRS DS2500 platform provides a fast accurate and sustainable alternative for sun protection factor determination in creams. The method streamlines quality control workflows and supports the growing demand for efficient analytical solutions in personal care industries.
References
- Metrohm NIR Application Note NIR-062 Determination of sun protection factor in creams using visible near infrared spectroscopy Version 1 July 2018
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