Associate Principal Scientist - Process Analytical Technology (PAT)
AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development, and commercialisation of prescription medicines for some of the world’s most serious diseases. But we’re more than one of the world’s leading pharmaceutical companies.
Associate Principal Scientist - Process Analytical Technology (PAT)
Introduction to Role
Are you ready to make an outstanding impact in the world of science? We have an exciting opportunity for you to join our dynamic and enthusiastic team at AstraZeneca, where we turn ideas into life-changing medicines. We are looking for an Associate Principal Scientist - Process Analytical Technology (PAT) to join our Technical Operations, Science and Innovation (TOSI) team. This role is pivotal in supporting the transformation of AZ commercial manufacturing through continuous direct compression (CDC) for oral solid dosage forms (OSDs).
Accountabilities
As an Associate Principal Scientist, you will provide expert support to continuous manufacturing of commercial products. Your knowledge in PAT, analytical science and technologies will be crucial in ensuring efficient and effective support to internal and external manufacturing sites and testing laboratories located in multiple countries. You will also play a proactive role in seeing opportunities for PAT method improvements and provide technical leadership to Issue Management Team (IMT).
Essential Skills/Experience
- Ph.D. – 3+ years, MS – 5+ years, BS – 8+ years of relevant industry experience. Degree in relevant field (Analytical Chemistry, Pharmaceutical Sciences, or Engineering etc.)
- Scientific leadership skills
- Proven track record to think and operate across functional boundaries
- Effective influencing and prioritization skills
- Good communication and stakeholder management skills
- A strong understanding of key process analytical technologies, especially NIR, Raman and microwave resonance spectroscopy
- Demonstrated expertise in PAT method development, implementation, optimization and use of Multi-variate data analysis/ Chemometrics (MVDA, PCA, PLS)
- Knowledge of the principles and management of Safety, Health & Environment (SHE)
- Business acumen and capability to understand business cases in subject matter areas.
Desired Skills/Experience
- Work experience in the Pharmaceutical industry in a PAT based role
- Experience in or exposure to multiple subject areas in CMC and related functions
- An understanding of other key analytical techniques such as separation science, NMR and mass spectrometry
- Previous experience and training in Lean, problem-solving tools and experience in data analysis and interpretation
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
