News from LabRulezICPMS Library - Week 20, 2025
LabRulez: News from LabRulezICPMS Library - Week 20, 2025
Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 12th May 2025? Check out new documents from the field of spectroscopy/spectrometry and related techniques!
👉 SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES
👉 Need info about different analytical techniques? Peek into LabRulezLCMS or LabRulezGCMS libraries.
This week we bring you guide by Agilent Technologies, application note by Shimadzu and other document by Thermo Fisher Scientific!
1. Agilent Technologies: The Basics of UV-Vis-NIR Spectrophotometry
A primer for Modern Materials Analysis
UV-Vis-NIR spectrophotometry is a powerful analytical technique used to study how materials interact with ultraviolet, visible, and near-infrared light. This method helps scientists investigate the electronic transitions in atoms and molecules, material compositions, and optical properties such as absorbance, reflectance, and transmittance across a broad wavelength range (typically 175 to 3300 nm).
At the heart of a spectrophotometer are key components: a light source, a monochromator to isolate specific wavelengths, a sample compartment, and detectors. Agilent offers a range of advanced instruments such as the Cary 5000, Cary 6000i, and Cary 7000 Universal Measurement Spectrophotometer (UMS). These systems enable high-precision measurements and support a wide variety of accessories—including diffuse and specular reflectance units, fiber-optic probes, and polarizers—tailored to different sample types and experimental needs.
Applications span multiple fields. In photovoltaics, UV-Vis-NIR spectrophotometers assess the quality and optical efficiency of solar cells by measuring diffuse reflectance and transmission. In semiconductor manufacturing, these instruments are used to map optical coatings and band gaps across wafers. In nanotechnology, they help characterize nanoparticles and quantum dots by identifying absorption profiles linked to particle size and dispersion.
The technique also plays a critical role in biosciences for quantifying proteins and nucleic acids, and in quality control processes for color consistency in food, textiles, and eyewear. The Cary systems from Agilent deliver reliable and repeatable results across these diverse applications, especially when combined with the powerful Cary WinUV software and certified reference materials.
Overall, UV-Vis-NIR spectrophotometry remains essential in both research and industry for its versatility, precision, and the rich insights it provides into material and molecular properties.
2. Shimadzu: Silicone Quantitation from Siliconized Rubber Stoppers by Using FTIR
- Application note
- Full PDF for download
User Benefits:
- The present work provides an easy extraction method for fast and accurate quantitation of silicone.
- The methodology can be adapted for extractable and leachable study of materials like pre-filled syringes, medical tubings and
various drug delivery systems.
Silicones are extensively employed in various industries due to their unique properties. In the pharmaceutical industry, they find numerous applications such as active ingredients, antifoaming agents, and excipients. They are also utilized in siliconization, pharmaceutical manufacturing operations, and packaging materials. Siliconization plays a vital role in the production of pre-fillable syringes, cartridges and rubber stoppers. Its purpose is to lubricate between the components which facilitates smooth gliding. It also enables a secure connection between the components like glass bottle and rubber stopper. By carefully optimizing the siliconization process parameters, it is possible to achieve a uniform coating while minimizing the presence of free silicone. To obtain quantitative information on the siliconization layers, it is essential to extract the silicone from siliconized components using organic solvents and then perform FTIR spectroscopy. This technique can provide crucial insights into the amount of silicone used on to the rubber stoppers. The present work demonstrates the application of FTIR for quantification of silicone in rubber stoppers.
Experimental
For the current study, the siliconized and non-siliconized rubber stoppers were collected from one of the manufacturers. Calibration curve was prepared by using USP reference standard Polydimethylsiloxane (PDMS). The measurements were performed on IRSpirit-ZX (Figure 1). The instrumental parameters are given in Table 1. The parameters used for measurement are referred from United States Pharmacopea1) .
Conclusion
Different grades of rubber samples were analyzed by FTIR using fixed thickness cell of NaCl, and excellent repeatability was obtained. The use of Hexane for extraction proved to be effective method for extraction of silicone from rubber stoppers. The % recovery obtained demonstrates the accuracy and reliability of the developed methodology. The method can be used for the routine analysis of rubber stopper samples to measure the content of silicone.
3. Thermo Fisher Scientific: iCAP MX Series ICP-MS
- Other document (Fact sheet)
- Full PDF for download
We are committed to designing our products with the environment in mind. This fact sheet provides the rationale behind the environmental claim that the Thermo Scientific™ iCAP™ MX Series ICP-MS uses up to 28% less energy. It is also responsibly packaged using 29% less material by weight and reduced in size by 22%.
Product description
The Thermo Scientific™ iCAP™ MSX Series ICP-MS offers the simplicity and productivity required in analytical testing laboratories, while the Thermo Scientific™ iCAP™ MTX ICP-MS provides the performance and flexibility needed to perform cutting-edge applications in research-oriented and testing laboratories.
Green features
More energy efficient
The previous model Thermo Scientific™ iCAP™ RQplus ICP-MS used 34.31 kWh during an 8-hour operating day. The new iCAP MSX ICP-MS uses 24.67 kWh during an 8-hour operating day, reducing the energy use by 28%.1 The iCAP MTX ICP-MS can be run interchangeably with a dry vacuum pump or the traditional oil vacuum pump, resulting in an energy savings of 25% when paired with the oil pump and 10% when paired with the dry pump (Table 1).
This savings represents 1.7 metric tons of CO2 equivalents annually, or the greenhouse gas emissions from driving approximately 4,305 miles in an average passenger car.2
The change in energy efficiency is due to the optimized vacuum pumps and decreased pumping speed in stand-by mode. When taking the chiller into account, we can expect an even higher energy efficiency as the new Thermo Scientific™ Qtegra™ ISDS Software controls the chiller, switching it off for stand-by mode.
