<h4><strong>Do you use results of chemical analyses as a basis for your decisions and judgements?</strong></h4><p>Those of us working in accredited laboratories or dealing with issues concerning the quality of measurements, would like to inform you about some important changes concerning the way the results of measurements are presented. These changes make it easier for you as an end-user to make correct decisions.</p><h4><strong>Nobody is perfect!</strong></h4><p>Results of analyses cannot be perfect! We hope this does not come as a big surprise to you. We use the term <strong>measurement uncertainty </strong>to describe this lack of perfection.</p><h4><strong>The analytical process</strong></h4><p>In each step of the analytical work, from sampling to the final measurement, deviations from the true value occur and measurement conditions vary. We take measures and perform controls regularly to assure that these deviations and variations together are small enough to make sure the end result fulfils your requirements. When we don’t have full information about all of the steps, e.g. when sampling and initial sample preparation are performed by you as a customer, you can assist us by providing detailed information about how that work was performed. Our experts are ready to advise on all matters regarding sampling. Please contact the laboratory beforehand.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Important_information_to_our_customers_concerning_the_quality_of_measurements_2_d885f6b051.jpg" alt="Eurachem: The analytical process" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Important_information_to_our_customers_concerning_the_quality_of_measurements_2_d885f6b051.jpg 139w," sizes="100vw" width="562" height="630"></p><h4><strong>Results should be fit-for-the-purpose</strong></h4><p>The accuracy of the results must of course not be too low nor too high since this would increase the costs. It should be fit for the intended purpose. If you are unsure on what level of accuracy you need, do not hesitate to contact the laboratory.</p><h4><strong>Uncertainty and limiting values</strong></h4><p>Many analyses are made to assure that limiting values are not exceeded. Without information about the measurement uncertainty it may appear to be very easy to make decisions, but these decision may be incorrect, with, e.g. economical consequences when rejecting instead of accepting a product, judicial consequences when returning a verdict of guilty instead of not guilty, or medical consequences when carrying out an unnecessary treatment. There are numerous examples!</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Important_information_to_our_customers_concerning_the_quality_of_measurements_3_f0ef8edc77.jpg" alt="Eurachem: Uncertainty and limiting values" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Important_information_to_our_customers_concerning_the_quality_of_measurements_3_f0ef8edc77.jpg 245w," sizes="100vw" width="932" height="453"></p><p>With a realistic measurement uncertainty the information included in the result becomes much more useful.</p><h4><strong>It will be easier to compare results</strong></h4><p>Most laboratories have until now chosen not to state measurement uncertainty in the test report. Instead, such information has only been given when the customer has asked for it</p><p>In the future, information about the measurement uncertainty will appear more frequently in the test report. It is also possible that you will bump into new and unfamiliar quality terms. This is due to the fact that there are new international guides and standards describing a common and partly new terminology. One of the objectives is to make it easier for you as a customer to compare test results.</p><h4><strong>What could it look like?</strong></h4><p>When reporting the test result we will give the normal information about what we have measured. When the results are followed by uncertainty statements, they are presented as intervals within which the true values are expected to lie with a certain level of confidence (usually 95%). In the example below the lead content is 1.65 ± 0.15 mmol·kg-1, that is between 1.50 and 1.80. The measurement uncertainty is also often reported relatively, in %.</p><ul><li><strong>Total lead content (Pb): </strong>1.65 mmol·kg<sup>-1</sup>&nbsp;</li><li><strong>Measurement uncertainty:</strong> 0.15 mmol·kg<sup>-1</sup> (9.1%)&nbsp;</li></ul><p>The stated uncertainty is an expanded measurement uncertainty (<i>U</i>). It was obtained by multiplying the combined standard uncertainty <i>u<sub>c</sub></i> with a coverage factor <i>k</i> equal to 2. This corresponds approximately to a 95 % confidence interval.</p><h4><strong>All’s well that ends well...</strong></h4><p>The requirements for a consistent way of reporting test results are increasing. Therefore, those of us involved in measurements are eager to assure ourselves that we understand your needs. You will notice this in your contacts with us before, during and after the test assignment. We hope that you will be satisfied with the final result.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Important_information_to_our_customers_concerning_the_quality_of_measurements_4_f870b1a7b8.jpg" alt="Eurachem: All’s well that ends well..." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Important_information_to_our_customers_concerning_the_quality_of_measurements_4_f870b1a7b8.jpg 159w," sizes="100vw" width="713" height="701"></p>

Important information to our customers concerning the quality of measurements

<h4><strong>A comprehensive analysis of renewable fuel testing technologies, automation, and ISO-compliant proximate analysis</strong></h4><p>The growing demand for renewable energy has increased the importance of accurate biofuel characterization. Biomass feedstocks and finished fuels must be carefully analyzed to ensure quality, efficiency, and compliance with international standards. LECO analytical instrumentation supports this work through automated and highly reliable analytical technologies.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/TGA_801_Termogravimetricka_analyza_vlhkosti_popela_tekavych_latek_a_ztraty_zihanim_b73c4cf493.jpg" alt="LECO: Advancing Biofuel Characterization with LECO Analytical Instrumentation: LECO’s TGA801, used for automated biofuel analysis." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_TGA_801_Termogravimetricka_analyza_vlhkosti_popela_tekavych_latek_a_ztraty_zihanim_b73c4cf493.jpg 245w," sizes="100vw" width="1164" height="435"></p><h3><strong>Automated Proximate Analysis with LECO’s TGA801</strong></h3><p>The<a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1877"> <strong>LECO TGA801 thermogravimetric analyzer</strong> </a>is designed for automated determination of moisture, volatile matter, and ash content in solid fuels. The system can analyze up to 19 samples simultaneously and combine all three parameters into one automated run, improving efficiency and reproducibility.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_Advancing_Biofuel_Characterization_with_LECO_Analytical_Instrumentation_31e96f1c96.jpg" alt="LECO Advancing Biofuel Characterization with LECO Analytical Instrumentation: TGA801 system with ceramic turntable and crucibles for ISO 18123 volatile matter determination." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_Advancing_Biofuel_Characterization_with_LECO_Analytical_Instrumentation_31e96f1c96.jpg 235w," sizes="100vw" width="860" height="573"></p><h3><strong>Comparison with ISO Reference Methods</strong></h3><p>To validate the performance of the automated TGA801 system, comparative studies were conducted using internationally recognized ISO reference methods. Moisture determination was compared with ISO 18134, ash content with ISO 18122, and volatile matter with ISO 18123. These standards prescribe specific temperatures and analytical procedures, but also permit automated systems if equivalent performance can be demonstrated.</p><p>The comparison included a broad range of materials such as wood pellets, peat, coal, plastics, and waste-derived fuels. Moisture and ash results generated by the TGA801 showed extremely close agreement with the manual ISO procedures. This strong correlation confirms that automated thermogravimetric analysis can provide the same reliability as conventional methods while greatly increasing throughput and reducing labor requirements.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_Advancing_Biofuel_Characterization_with_LECO_Analytical_Instrumentation_2_3887128788.jpg" alt="LECO: Advancing Biofuel Characterization with LECO Analytical Instrumentation: ISO method crucibles for manual volatile determination." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_Advancing_Biofuel_Characterization_with_LECO_Analytical_Instrumentation_2_3887128788.jpg 172w," sizes="100vw" width="1264" height="1145"></p><h3><strong>Volatile Matter Correlation Results</strong></h3><p>For volatile matter analysis, both ISO and TGA procedures measure mass loss during a fixed period at 900 °C. The TGA method introduces an additional heating ramp from the moisture determination step at approximately 105 °C to the higher volatile matter temperature. Despite this procedural difference, the resulting data demonstrated excellent agreement.</p><p>Testing performed on wood pellets showed a strong linear relationship between the ISO and TGA methods with an R² value of approximately 0.94. The maximum deviation observed was only 1.06%, while the average difference between methods was approximately 0.1%. These results confirm the ability of the TGA801 to produce highly accurate volatile matter measurements across a variety of biomass and fuel matrices.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_Advancing_Biofuel_Characterization_with_LECO_Analytical_Instrumentation_2_40f7189cef.jpg" alt="LECO Advancing Biofuel Characterization with LECO Analytical Instrumentation: Correlation and comparative data between ISO methods and LECO TGA analysis." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_Advancing_Biofuel_Characterization_with_LECO_Analytical_Instrumentation_2_40f7189cef.jpg 172w," sizes="100vw" width="1065" height="967"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_Advancing_Biofuel_Characterization_with_LECO_Analytical_Instrumentation_1_7519e8e646.jpg" alt="LECO Advancing Biofuel Characterization with LECO Analytical Instrumentation: Correlation and comparative data between ISO methods and LECO TGA analysis." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_Advancing_Biofuel_Characterization_with_LECO_Analytical_Instrumentation_1_7519e8e646.jpg 228w," sizes="100vw" width="1641" height="1120"></p><h3><strong>Advantages of Automated Biofuel Analysis</strong></h3><ul><li>High sample throughput with simultaneous multi-sample analysis.</li><li>Fully automated workflows reducing operator involvement.</li><li>Integrated determination of moisture, ash, and volatile matter in one run.</li><li>Excellent reproducibility and data consistency.</li><li>Strong agreement with ISO reference methods without additional calibration.</li><li>Improved data security and laboratory efficiency.</li><li>Suitable for research laboratories, industrial quality control, and fuel certification.</li></ul><h3><strong>Automate Your Lab Today</strong></h3><p>LECO analytical instrumentation provides a comprehensive solution for modern biofuel characterization. From calorific value determination and elemental composition analysis to ash fusibility and automated proximate analysis, these technologies support both scientific research and industrial production with fast, reliable, and reproducible results.<br><br>The TGA801 demonstrates how automation can significantly improve laboratory efficiency while maintaining full compliance with ISO reference methods. By integrating moisture, ash, and volatile matter analysis into a single automated workflow, the system reduces labor requirements, increases throughput, and enhances data quality.<br><br>As renewable energy continues to expand globally, advanced analytical systems will remain essential for ensuring fuel quality, supporting regulatory compliance, and driving innovation in sustainable energy technologies. <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1877"><strong>Explore the features of the LECO TGA801 today.</strong></a></p>

Advancing Biofuel Characterization with LECO Analytical Instrumentation

<p><strong>In the week from July 6, the following webinars await you in the field of atomic and molecular spectroscopy and spectrometry</strong></p><blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4><p><strong>👉 Search and filter in the largest global database</strong> with over <strong>5 500 GC, LC, MS and spectroscopy webinars</strong>.</p></blockquote><h5><strong>1. Thermo Fisher Scientific: Lunch and Learn Tips and Tricks Series: Trace Elemental Analysis (ICP-OES &amp; ICP-MS)</strong></h5><ul><li>Tu, 7.7.2026 12:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/5977">Registration</a></li></ul><p>Learn practical tips to optimize ICP-OES and ICP-MS performance, improve data quality, streamline troubleshooting and maintenance, and enhance sample preparation for more efficient elemental analysis.</p><h5><strong>2. SelectScience: Expanding the 4D-STEM Toolbox for Advanced Materials Characterization</strong></h5><ul><li>Tu, 7.7.2026 15:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6318">Registration</a></li></ul><p>Explore how Timepix4 detector technology advances 4D-STEM workflows, enabling high-resolution imaging, data-driven acquisition, and new opportunities in electron microscopy.</p><h5><strong>3. Anton Paar: Microwave Digestion: The Foundation of Accurate Trace Metal Analysis</strong></h5><ul><li>We, 8.7.2026 09:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6321">Registration</a></li></ul><p>Build robust workflows for trace metal analysis. Learn how microwave digestion ensures fast, contamination-free, and complete sample preparation across complex food matrices.</p><h5><strong>4. Wiley: From liquids to solids: expand what your UV-Vis-NIR Spectrometer can do</strong></h5><ul><li>We, 8.7.2026 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6367">Registration</a></li></ul><p>Discover how the Agilent Cary UV-Vis-NIR spectrometer, together with Specac accessories, enables reliable analysis of liquids, powders, films, pellets, and highly scattering solid samples.</p><h5><strong>5. SelectScience: The next generation ICP-MS designed to wow trace element analysts</strong></h5><ul><li>We, 8.7.2026 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6320">Registration</a></li></ul><p>Upgrade your trace-element analysis. Discover how the new Agilent 9500 ICP-MS eliminates interferences and simplifies method development for complex matrices.</p><h5><strong>6. LECO: Dry Matter and Ash Determination in Wastewater and Sewage Sludge</strong></h5><ul><li>Th, 9.7.2026 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6324">Registration</a></li></ul><p>Optimize wastewater analysis. Learn how automated thermogravimetric analysis (TGA) replaces manual drying and ashing steps to determine dry matter and ash in sewage sludge.</p><h5><strong>7. Waters Corporation: Cracking the Code on Nitrogen Methods</strong></h5><ul><li>Th, 9.7.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6327">Registration</a></li></ul><p>Learn the fundamentals of nitrogen analysis for wastewater testing. Explore analytical methods, QA/QC, sample handling, compliance reporting, and troubleshooting for accurate environmental monitoring.</p><h5><strong>8. Agilent Technologies: ICP Expert 7.8: Booming ICP-OES Software Innovation</strong></h5><ul><li>Th, 9.7.2026 20:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/6368">Registration</a></li></ul><p>Discover what's new in ICP Expert™ 7.8 and how the latest software innovations can improve data quality, simplify routine operation, and increase day-to-day laboratory efficiency.</p>

Webinars LabRulezICPMS Week 28/2026

Article

Product

Webinars

Application

Academy

Eurachem is a European network promoting international traceability of chemical measurements and good analytical practice. It provides expert guidance, supports method validation, uncertainty evaluation, proficiency testing, and facilitates discussion on technical and policy issues in analytical quality.

Eurachem

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

In 1936, the Laboratory Equipment Company introduced the first rapid carbon determinator for the American iron and steel industry.  Today, almost 80 years later, LECO is recognized globally as a leader in the development of high-quality analytical instrumentation, mass spectrometers, comprehensive two-dimensional chromatography, metallography & optical equipment as well as consumables.

LECO

Anton Paar

Agilent Technologies

SelectScience

C&EN

<p><strong>Is your raw material identification (ID) testing process optimized? Can it handle a high volume of receipts without stretching your QC budget? If you use a sampling booth and/or open papers sacks, plastics buckets/drums, or other commonly used pharmaceutical containers to ID excipients, API, or other raw materials, your ID process can be improved.</strong></p>
<p>This webinar will describe how raw material verification testing is now possible through transparent and non-transparent packaging directly in quarantine using Spatially Offset Raman Spectroscopy (SORS). The Agilent Vaya Raman is the first handheld spectrometer incorporating SORS to quickly identify raw materials directly through containers in a cGMP environment. This webinar will also discuss SORS technology, its impact on the ID test process, and subsequent return on investment (ROI) against current ID testing solutions.</p>
<h5><strong>Key learning objectives</strong></h5>
<ul>
<li>Understand how raw material identity verification through transparent and non-transparent containers removes the need for sampling, increasing testing throughput without increasing costs</li>
<li>Learn how the Vaya system, with true through-barrier SORS technology, works through most common containers – from clear glass vials to multilayer paper sacks</li>
<li>Learn how Vaya improves current testing protocols – from low volume sampling to 100% ID testing</li>
<li>Discover the ROI against classic conventional Raman handhelds and NIR systems</li>
<li>Understand how to streamline an identification process with Vaya</li>
</ul>
<h5><strong>Who should attend?</strong></h5>
<ul>
<li>QC lab managers, analysts, and scientists</li>
<li>Raw material managers</li>
<li>Plant managers</li>
<li>Operation efficiency managers</li>
<li>Continuous improvement managers</li>
<li>Vice Presidents of Quality and Operations</li>
<li>PAT scientists</li>
</ul>
<blockquote>
<p><strong>Presenter: Frederic Prulliere (Raman ID Product Manager, Agilent Technologies)</strong></p>
</blockquote>
<blockquote>
<p>Frederic Prulliere is the Product Manager for the Raman ID product line at Agilent Technologies. Prulliere leads the product development of spatially offset Raman spectroscopy-based solutions, particularly for verifying raw materials at reception. He joined Agilent Technologies in 2012 as a business development manager for mobile Fourier transform infrared spectroscopy (FTIR).</p>
</blockquote>


SelectScience: Rapidly scan your raw materials with SORS

Rapidly scan your raw materials with SORS

We will describe how raw material verification testing is now possible through transparent and non-transparent packaging directly in quarantine using SORS.

<p><strong>Can the TopScan 4300 FTIR test liquid?  What is the detection limit of the 4300 FTIR? Is ambient light an issue for Vaya Raman spectrometer?</strong></p>
<p>Lets discuss some of the most common questions about Agilent Handheld spectrometers.</p>
<blockquote>
<p><strong>Presenter:</strong> Yanqia Wang, PhD (Application Engineer, Molecular Spectroscopy, Agilent Technologies, Inc.)</p>
</blockquote>
<blockquote>
<p>Dr. Yanqia Wang started working for Agilent Technologies Inc. as a FTIR application Engineer in 2013, providing pre-&amp;post-sale application support. The products he covers from Bench-top FTIR microscopes to various Mobile FTIR spectrometers. Dr. Wang received his PhD of analytical chemistry from Duke University in 2004, doing dynamic IR spectroscopy research. Then he joined Fitzpatrick Center for Photonics at Duke University, doing Tissue Raman spectrometer instrumentation. Since 2007, Dr. Wang worked for Avery Dennison Corp. as a spectroscopist, providing molecular analytical support to the research &amp; development.</p>
</blockquote>


Agilent Technologies: Common Handheld FTIR and Raman Questions Answered

Common Handheld FTIR and Raman Questions Answered

Lets discuss some of the most common questions about Agilent Handheld spectrometers.

<p><strong>You might be facing challenges with respect to material identification process and its qualification.</strong></p>
<p>Now, with Agilent&#39;s trusted solution - Vaya Raman Spectometer, confidently identify pharmaceutical materials and meet the performance specifications of global pharmacopoeia.</p>
<blockquote>
<p><strong>Presenter:</strong> Rob WIlls (Molecular Spectroscopy Specialist, Agilent Technologies)</p>
</blockquote>


Agilent Technologies: Raw Material ID and Raman

Raw Material ID and Raman

Challenges with respect to material identification process and its qualification.

<p><strong>Real-time analytics using in-line and on-line technologies provide valuable insights into bioprocess parameters and cell-feeding strategies. Leveraging Process Analytical Technology (PAT), bioproduction processes can be optimized to deliver exceptional results. This includes developing scalable and transferrable processes in monoclonal antibody (mAb) bioproduction. PAT is a game-changer in the bioproduction industry, empowering manufacturers to stay ahead in a highly competitive market.</strong></p>
<p>In this webinar, Dr. Nimesh Khadka, a senior R&amp;D scientist at Thermo Fisher Scientific, will discuss how PAT in bioproduction is revolutionizing how premium products can be developed and manufactured. He will also explore the benefits of the implementation of PAT in bioproduction, including improved process efficiency, reduced manufacturing costs, and the ability to deliver high-quality products consistently.</p>
<h5><strong>Key learning objectives</strong></h5>
<ul>
<li>Learn what the advantages are of Raman Spectroscopy as Process Analytical Technology (PAT)</li>
<li>Explore case studies that show the implementation of Raman as PAT for upstream and downstream processes</li>
<li>Understand how to use chemometrics as a tool to extract useful information from the complex matrix</li>
<li>Discover how the Thermo Scientific™ MarqMetrix™ All-In-One Process Raman Analyzer is a reliable, scalable, and accurate instrument with minimum inter-instrument variability allowing model transferability across instruments</li>
</ul>
<h5><strong>Who should attend?</strong></h5>
<ul>
<li>Process engineers</li>
<li>PAT scientists</li>
<li>Process development &amp; team leaders</li>
<li>R&amp;D team leaders</li>
<li>Process improvement champions</li>
<li>Those working in cell culture/bioproduction</li>
</ul>
<h5><strong>Certificate of attendance</strong></h5>
<p>All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.</p>
<blockquote>
<p><strong>Presenter:</strong> Dr. Nimesh Khadka (Thermo Fisher Scientific)</p>
</blockquote>
<blockquote>
<p>Dr. Nimesh Khadka is a senior R&amp;D scientist with the Field Safety Instruments at Thermo Fisher Scientific, specializing in analytical biochemistry, spectroscopy, and chemometrics. He currently champions Raman spectroscopy as process analytical technology (PAT) for developing protein and nucleic acids therapeutics. He completed his Ph.D. at Utah State University, focusing on enzymology, spectroscopy, and alternative bio-energy. His postdoctoral training was conducted at Case Western Reserve University, where he dedicated his research to studying structural biology in biomolecules associated with eye pathologies. As an active member of the American Chemical Society, he remains at the forefront of emerging technologies and is committed to driving innovation to meet customer’s needs.</p>
</blockquote>
<blockquote>
<p><strong>Presenter:</strong> Will Thompson (SelectScience)</p>
</blockquote>
<blockquote>
<p>Will studied Biology at the University of Bristol, UK, and as a member of the Editorial team, he now plays an integral role in shaping the content on SelectScience.</p>
</blockquote>


SelectScience: Unlocking the Potential: Raman Spectroscopy as Real-time Process Analytical Technology (PAT) for Automation and Enhanced Bioproduction

Unlocking the Potential: Raman Spectroscopy as Real-time Process Analytical Technology (PAT) for Automation and Enhanced Bioproduction

In this webinar, we will discuss how PAT in bioproduction is revolutionizing how premium products can be developed and manufactured.

Raman Spectroscopy as Process Analytical Technology

<p><strong>The global pharmaceutical market's growth has led to an alarming increase in substandard and falsified (SF) medicines, posing significant risks to public health.</strong></p><p>These dangerous products compromise patient safety and treatment efficacy, particularly in critical areas, such as antimalarials and antibiotics. Rapid, accurate detection methods are essential to combat this growing threat and ensure medication integrity across various settings, from pharmacies to field inspections.</p><p>In this webinar, Drs. Basant Giri (Kathmandu Institute of Applied Sciences) and Toni Barstis (Saint Mary’s College) will share insights about their collaboration in Nepal where there were 346 drug recalls during the period from 2010 through 2020, with approximately 75% of those being substandard or falsified. Giri and Barstis are using novel paper-based devices and a handheld Raman spectrometer for field-expedient testing and more advanced method development. They will demonstrate how these tools can work together to improve the safety and efficacy of pharmaceuticals and the safety of consumer products. Adam Hopkins, Spectroscopy Product Manager from Metrohm USA, will briefly discuss the unique features of the MIRA handheld Raman analyzer that make it ideal for this critical work</p><h4>Key Learning Objectives:</h4><ul><li><strong>Insight into the sacle of the SF medicine problem: Information crucial for audience to understand the scope of the issue and its potential impact on their operations and reputation</strong></li><li><strong>The underlying science behind field-expedient testing methods: Knowledge is relevant for QA teams and forensic chemists who need to implement or improve field-testing protocols</strong></li><li><strong>Discover a practical example of how to apply Raman in a real-world setting: Benefits those involved with global supply chain management and international quality assurance efforts</strong></li><li><strong>Technological advancements in handheld Raman: Helps decision-makers considering investments in new quality control equipment</strong></li></ul><h4>Who Should Attend:</h4><ul><li>VPs and Chiefs of Product Quality</li><li>Quality assurance and management team members and leads</li><li>Supply chain managers</li><li>Forensic chemists and scientists</li><li>Anyone involved in or curious about pharmacovigilance activities</li></ul><blockquote><p><strong>Presenter: </strong>Dr. Basant Giri (Senior Scientist, Kathmandu Institute of Applied Sciences)</p><p><strong>Presenter:&nbsp;</strong>Dr. Toni L.O. Barstis (Professor Emeritus, Saint Mary’s College, Notre Dame, IN)</p><p><strong>Presenter:&nbsp;</strong>Dr. Adam J. Hopkins (Spectroscopy Product Manager, Metrohm USA)</p><p><strong>Presenter:&nbsp;</strong>Ann Thayer (Contributing Editor, C&amp;EN Media Group)</p></blockquote>

C&EN: In-field Identification of Low-Quality Medicines using Handheld Raman

In-field Identification of Low-Quality Medicines using Handheld Raman

The global pharmaceutical market's growth has led to an alarming increase in substandard and falsified (SF) medicines.

In-field Identification of Low-Quality Medicines

<p><strong>Switching to a portable Raman device that can read through both transparent and non-transparent containers will help you move towards “zero waste”, drastically reduce sampling and associated costs, and increase productivity.&nbsp;</strong></p><p>The Agilent Raman Raw Material Identity Verification System (Vaya) enables zero-waste workflows with its new unique spatial shift Raman spectroscopy (SORS) technology, enabling raw materials to be verified through opaque and transparent containers. This unique innovation eliminates the need to sample most raw materials, significantly reducing unnecessary waste of time, personnel, and materials. Additionally, Vaya has received the Accountability, Consistency and Transparency (ACT) label certification from My Green Lab, highlighting the development and life cycle of environmentally friendly products.</p><p><strong>Key learning objectives: &nbsp; &nbsp;</strong> &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;</p><ul style="list-style-type:disc;"><li style="tab-stops:list 36.0pt;">Discover how we can identify materials through transparent and non-transparent packaging.</li><li style="tab-stops:list 36.0pt;">Learn how to build a robust method to avoid false positive identifications.</li><li style="tab-stops:list 36.0pt;">See how you can drastically reduce your consumables.</li></ul><blockquote><p><strong>Presenter:</strong> &nbsp;Rob Wills (Molecular Spectroscopy Specialist, Agilent Technologies)</p><p>Rob joined Agilent Technologies in March 2011 as Product Specialist for Molecular Spectroscopy covering UK, Ireland and Nordics. He has a wealth of technical and business experience accumulated over 30 years in the laboratory instrumentation business, during which time he has held a variety of roles. In his current role he acts as the technical liaison between the end user customer and the sales team, advising and creating solutions based on Agilent’s spectroscopy range that help give our customers the trusted answers they need and the valued insights they seek.</p></blockquote>

Agilent: Raw Material ID Through Non-Transparent Packaging Using Agilent Vaya Handheld Raman

Raw Material ID Through Non-Transparent Packaging Using Agilent Vaya Handheld Raman

If you regularly receive a large number of raw materials from a variety of suppliers at a high frequency, this webinar is for you!

Raw Material ID Using Agilent Vaya Raman

<p><strong>A real bottleneck in GMP environments can be the verification and release of incoming raw materials. Agilent's Raman systems for raw material identification can alleviate this by making measurements through opaque containers using spatially offset Raman spectroscopy (SORS).&nbsp;</strong></p><p>We will discuss Agilent's handheld Vaya and mobile RapID solutions as well as demonstrate the Vaya's capabilities.</p><blockquote><p><strong>Presener: </strong>Scott Melis, PhD (Application Scientist, Agilent Technologies, Inc.)</p><p>Scott Melis has a PHD in Physics from Georgetown University in Washington, DC and started with Agilent in 2021 as a Molecular Spectroscopy Application Scientist. In his graduate work, Scott studied nanoparticle formation and growth for a variety of applications. Projects that he worked with include developing processes to deposit and characterize semiconducting molecular nano-cocrystals for use in optoelectronic devices as well as controlling polymer nanoparticle size through rapid mixing conditions.</p></blockquote>

Agilent Technologies: Advance Your Raw Material ID: How Handheld Raman Can Verify Materials Through Opaque Packaging

Advance Your Raw Material ID: How Handheld Raman Can Verify Materials Through Opaque Packaging

We will discuss Agilent's handheld Vaya and mobile RapID solutions as well as demonstrate the Vaya's capabilities.

Handheld Raman: Verifying Materials Through Opaque Packaging

<p><strong>The fundamentals of fluorescence analysis will be discussed. Topics considered will be choosing the best excitation wavelength, identifying interferences like the Raman band and second order peaks from the monochromator. Concentration quenching, environmental factors, and a variety of other factors will be discussed.</strong></p><blockquote><p><strong>Presenter:&nbsp;</strong> Dean Brown (Application Scientist, Molecular Spectroscopy, Agilent Technologies, Inc.)</p><p>A graduate of the University of Maryland and West Virginia University. Started as research scientist at Johns Hopkins School of Medicine developing clinical laboratory assays. Transitions to an Applications Scientist for Uv/Vis/Nir, Fluorescence, IR and Raman spectroscopy. He has published numerous papers in the field of molecular spectroscopy and served on a number of Committees.</p></blockquote>

Agilent Technologies: Agilent Webinars On Demand

Back to Basics with Fluorescence: A Tips & Tricks Workshop

The fundamentals of fluorescence analysis will be discussed - choosing the best excitation wavelength, identifying interferences and a variety of other factors.

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><p><strong>This session will delve into model training, method validation, tips and tricks to improve or ensure method robustness and custom methods.</strong></p><p>Don't miss this opportunity to enhance your understanding and skills!</p><blockquote><p>First session: <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/5748"><strong>Watch on-demand here</strong></a></p></blockquote><h5><strong>In this webinar, you'll learn:</strong></h5><ul><li>How to build method training&nbsp;</li><li>Method validation</li><li>How to ensure model robustness on the Vaya?</li><li>What is a custom method on Vaya?</li></ul><p>This webinar is beneficial for all Vaya users or any pharma/biopharma customers interested to know more on through-packaging raw materials identification.</p><blockquote><p><strong>Presenter:</strong> Chris Welsby (Raman ID Product Line Manager, Agilent Technologies)</p><p>Chris is a PhD chemist, graduating from Cardiff University in 2001 having studied heterogenous catalysis, now focusing on molecular spectroscopy products intended for the pharma industry, namely Spatially Offset Raman Spectroscopy (SORS) through barrier technology, to enable verification of raw material ID through packaging in the warehouse environment. Chris has worked as part of the marketing team on Spatially Offset Raman applications since 2016, firstly as an Applications Scientist and latterly as a Marketing Product Manager of the Vaya handheld for raw material ID.</p></blockquote></div></div></div>

Agilent Technologies: Tip and Tricks – How to Best Use the Handheld Raman Vaya

Tip and Tricks – How to Best Use the Handheld Raman Vaya

Join us for the second session on Vaya Method Development Tips and Tricks!

How to Best Use Handheld Raman Vaya

<p><strong>Crystallinity strongly affects the mechanical, thermal, and barrier properties of polymer films, yet monitoring it during extrusion is difficult. This work presents an integrated workflow using thermal analysis, Raman spectroscopy, lab‑scale film extrusion, and optical film‑quality inspection to predict and confirm crystallinity and overall product quality in LDPE/PEEK. Thermal analysis provides precise enthalpy of fusion values and baseline crystallinity (typically 35–45%), establishing robust reference data. These values inform calibration of Raman regression models built from C‑H and skeletal vibration bands, enabling rapid, non‑destructive crystallinity forecasting.</strong></p><p>Using <strong>Anton Paar Brabender</strong> extrusion equipment, the Raman model is validated in real time during LDPE/PEEK film production, capturing crystallinity changes such as shear‑induced reductions after extrusion. Complementing this, the Film Quality Analyzer identifies defects including black specks, gels, fisheyes, and holes (ASTM D7310). Together, these tools help polymer scientists enhance film uniformity, prevent defects, and accelerate process optimization.</p><h4><strong>Key Learning Objectives:</strong></h4><p><strong>1. Understand how crystallinity governs polymer film performance</strong></p><ul><li>Viewers will learn why crystallinity is critical for mechanical, thermal, and barrier properties of LDPE/PEEK films and why real‑time monitoring during extrusion is challenging but essential for product quality.</li></ul><p><strong>2. Learn how to quantify crystallinity using thermal and spectroscopic tools</strong></p><ul><li>They will see how thermal analysis establishes accurate baseline crystallinity values and how Raman spectroscopy—calibrated with those values—can rapidly and non‑destructively predict crystallinity in real time.</li></ul><p><strong>3. Discover how to validate crystallinity models during extrusion</strong></p><ul><li>The audience will understand how lab‑scale single‑screw extrusion combined with in‑line Raman analysis tracks crystallinity changes under real processing conditions, including shear‑induced disorder.</li></ul><p><strong>4. Recognize how optical film‑quality analysis ensures defect‑free products</strong></p><ul><li>They will learn how an optical Film Quality Analyzer detects defects such as black specks, gels, fisheyes, and holes, enabling consistent, standards‑based quality control (ASTM D7310).</li></ul><blockquote><p><strong>Speaker: </strong>Christoph Pielen</p><p>After earning his degree from RWTH Aachen University in Germany, Christoph Pielen joined Brabender GmbH in 2012 as an Application Specialist. He later becoming Laboratory Manager and then President of Brabender CWB in the U.S., where he supported ASTM standard development and customer applications. Following Brabender's 2023 acquisition by Anton Paar, Christoph now serves as Lead Scientist for Texture and Extrusion at Anton Paar USA.</p><p>Outside work, Christoph enjoys traveling, skiing, and spending time with his two children, Alexander and Victoria, while pursuing his passion for aviation and space exploration.</p></blockquote>

Anton Paar: From Analysis to Assurance: How Thermal, Raman, and Film Extrusion Techniques Validate Crystallinity and Ensure Polymer Product Quality