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AI-Assisted Nanomechanical AFM Analysis in a Multi-Compartment Environment

RECORD | Already taken place We, 21.5.2025
Join us and special guest Dr. Upnishad Sharma, ETH Zurich, for this webinar on the AI-Assisted Analysis of the Nanomechanical Properties of Biological Samples in a Multi-Compartment Environment using AFM.
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Bruker: AI-Assisted Nanomechanical AFM Analysis in a Multi-Compartment Environment
Bruker: AI-Assisted Nanomechanical AFM Analysis in a Multi-Compartment Environment

Join us and special guest speaker Dr. Upnishad Sharma, ETH Zurich, for this webinar on the AI-Assisted Analysis of the Nanomechanical Properties of Biological Samples in a Multi-Compartment Environment using AFM.

Recent developments have greatly extended the functionality of atomic force microscopes (AFM) to enable high resolution imaging and nanomechanical analysis in multiwell cell culture plates. This greatly extends the range, speed, and versatility of experiments possible, increases throughput and productivity, and generates statistically relevant datasets.

Discover next-generation capabilities:

  • Autonomous AI-guided operation and advanced machine-learning capabilities for the automated identification and measurement of sample features
  • Seamless integration with advanced optical microscopy
  • Study living cells, tissues, 3d cell structures, and organoids under near-native conditions

Dr. Upnishad Sharma, a postdoctoral researcher in the lab of Prof. Daniel Mueller, will speak on investigating integrin-mediated mechanosensing in the extracellular matrix (ECM) using AFM-based Single-Cell Force Spectroscopy (SCFS).

Don’t miss the LIVE demonstration, where we will perform nanomechanical AFM measurements using the new CellWizard Stage.

Program - Wednesday, May 21st, 2025

17:00 AM CEST | 8:00 AM PDT | 11:00 EDT

17:00 Welcome & Introduction
  • Oilibhe Pabsch, Scientific Affairs Manager, Bruker BioAFM
17:05 Dissecting Integrin-Mediated ECM-Sensing using AFM-based SCFS
  • Dr. Upnishad Sharma, Dpt. of Biosystems Science and Engineering, ETH Zurich, Switzerland
17:35 LIVE Demonstration: CellWizard Stage and NanoWizard V BioAFM
  • Dr. André Körnig, Senior Applications Scientist, Bruker BioAFM
    17:50 Q&A
18:00 Closing

Presenter: Dr. Upnishad Sharma (Lab Group Prof. Daniel Mueller, ETH Zurich, Switzerland)

Dr. Upnishad Sharma, a Postdoctoral researcher in the lab of Prof. Daniel Mueller at the Department of Biosystems Science and Engineering, ETH Zurich, completed his PhD at ETH Zurich in 2024 and Masters in Life
Sciences between University of Mumbai and EMBL-Rome in 2018. Previously, he worked in the field of epigenetics and cell biology. Currently, his interests lie in the biophysical aspects of integrin mediated mechanotransduction during development and disease).

Presenter: Oilibhe Pabsch (Scientific Affairs Manager, Bruker BioAFM)

Presenter: Dr. André Körnig (Senior Applications Scientist, Bruker BioAFM)

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