<p><strong>The biennial conference is organized by Department of Analytical Chemistry, Faculty of Science, Palacky University in cooperation with Czech Chemical Society and Czech Society for Mass Spectrometry. It is organized as a meeting of the scientists from the universities, academic institutes and experts from the routine analytical laboratories.</strong></p><p>The scientific programme of the conference highlights the <strong>latest advances</strong> in analytical chemistry, chromatography, mass spectrometry, metabolomics, microextraction, multidimensional separations, and data-driven analytical workflows. Participants can look forward to plenary lectures from internationally recognized experts, <strong>specialized sessions covering LC-MS, GC×GC, SFC-MS, MALDI-MS</strong>, <strong>capillary electrophoresis, and multiomics,</strong> as well as poster sessions, vendor presentations, and networking events connecting academic researchers with industry professionals.</p><h3><strong>Registration</strong></h3><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://www.upol.cz/chiranal/registration/"><strong>Register for the conference HERE</strong></a></p><ul><li><strong>Conference Fees:</strong> 6.000,- CZK / 250 EUR &nbsp;without VAT</li><li><strong>Deadline for registration is May 31st, 2026.</strong></li></ul></blockquote><h3><strong>Programme</strong></h3><h4><strong>Monday 15th June 2026, Fort Science</strong></h4><h5><strong>14:00 - 17:30 Registration, individual arrival of participants and accommodation</strong></h5><h5><strong>16:00 - 16:15 Opening of the conference, presentation of official representatives of the conference partners</strong></h5><ul><li>Foreword: Petr Bednář</li></ul><h5><strong>16:15 - 17:15 Plenary Lecture: Metabolomics and Lipidomics in Biomedical Research</strong></h5><ul><li>Michael Laemmerhofer</li></ul><h5><strong>17:30 - ??? Welcome party + banquet</strong></h5><h4><strong>Tuesday 16th June 2026</strong></h4><h5><strong>8:30 – 9:00 Breakfast (Faculty of Science, foyer, 2nd floor), installation of posters (Faculty of Science, seminary rooms, 2nd floor)</strong></h5><h5><strong>9:00 – 9:30 Breaking boundaries in natural product analysis with SFC-MS</strong></h5><ul><li>Lucie Nováková</li></ul><h5><strong>9:30 – 10:00 Data science-assisted method development for on-line supercritical fluid extraction – chromatography</strong></h5><ul><li>Kevin Schug</li></ul><h5><strong>10:00 – 10:20 Predicting Chromatographic Retention Times: Descriptor Choice, Feature Selection, and QSAR Interpretation</strong></h5><ul><li>Roman Szucs</li></ul><h5><strong>10:20 – 10:40 Development of Novel Calibration Methods and Their Application to the Chromatographic Determination of Bisphenols</strong></h5><ul><li>Paweł Świt</li></ul><h5><strong>10:40 – 11:00 Applications of online SFE – SFC: A Powerful Tool for Small Molecule Extraction and Analysis</strong></h5><ul><li>Kevin Schug (Shimadzu)</li></ul><h5><strong>11:00 - 11:30 </strong>Coffee break</h5><h5><strong>11:30 - 12:00 Enantioselective Ion Pairing Systems, my 50 years of Contribution</strong></h5><ul><li>Wolfgang Lindner&nbsp;</li></ul><h5><strong>12:00 - 12:30 The future of multimodal chiral stationary phases</strong></h5><ul><li>Michal Kohout</li></ul><h5><strong>12:30 - 12:50 Analytical Challenges in the Development of Voclosporin HPLC methods : Application of High Temperature Liquid Chromatography in pharmaceutical analysis</strong></h5><ul><li>Pavel Blatný (TAPI Czech Industries s.r.o.)&nbsp;</li></ul><h5><strong>13:10 - 13:30 Next-Gen Zwitterionic HILIC: Particle Morphology Matters</strong></h5><ul><li>Petra Lewits (Merck)</li></ul><h5><strong>13:30 - 15:00 </strong>Lunch</h5><h5><strong>15:00 - 16:30 Poster session I (even poster numbers) and coffee break (Faculty of Science, foyer, seminary rooms, 2nd floor)</strong></h5><h5><strong>16:30 - 17:00 Quantification of polyethylene in compostable plastic formulations by analytical pyrolysis-based methods with split modulation</strong></h5><ul><li>Marco Mattonai</li></ul><h5><strong>17:00 - 17:30 Untargeted Analysis of a Late Classic Period Maya Femur by Comprehensive Two-Dimensional Gas Chromatography (GCxGC)</strong></h5><ul><li>Petr Vozka</li></ul><h5><strong>17:30 - 17:50 Theoretical Decomposition and Practical Mitigation of Matrix Effects in Quantitative LC–MS Calibration</strong></h5><ul><li>Ivan Petřík&nbsp;</li></ul><h5><strong>17:50 - 18:10 Feed Injection-Enabled 2D-LC/MS for Enhanced Analyses of Lipophilic Drug Formulations</strong></h5><ul><li>Daniel Foshag (Agilent Technologies)</li></ul><h5><strong>18:10 - 18:30 Modern approach for analytical and preparative liquid chromatography by ECOM manufacturer</strong></h5><ul><li>Ondřej Kuchler (ECOM)&nbsp;</li></ul><h5><strong>18:30 - 19:30 </strong>Dinner (university cafeteria)<br>&nbsp;</h5><h4><strong>Wednesday 17th June 2026</strong></h4><h5><strong>8:30 – 9:00 Breakfast (Faculty of Science, foyer, 2nd floor), installation of posters (Faculty of Science, seminary rooms, 2nd floor)</strong></h5><h5><strong>9:00 – 9:30 The Role of Analytical Chemistry in Solving Contemporary Challenges in Biomethane Plants</strong></h5><ul><li>Justyna Płotka-Wasylka</li></ul><h5><strong>9:30 – 10:00 Centrifugation-assisted micro-extraction using functionalized glass beads for rapid HPLC analysis</strong></h5><ul><li>&nbsp;František Švec</li></ul><h5><strong>10:00 – 10:20 A Simple Microextraction Technique: PT-µSPE</strong></h5><ul><li>Massoud Kaykhaii</li></ul><h5><strong>10:20 – 10:40 LC-MS/MS Salicylate Profiling in Arabidopsis Thaliana Plants under Infection with Pathogens of Different Lifestyles</strong></h5><ul><li>Jitka Široká</li></ul><h5><strong>10:40 – 11:00 Chromline: Performance &amp; Innovation</strong></h5><ul><li>Štěpán Dostál (Chromservis)</li></ul><h5><strong>11:00 - 11:30 </strong>Coffee break</h5><h5><strong>11:30 - 12:00 Rational approaches to MALDI-MS matrix design</strong></h5><ul><li>Hans-Dieter Junker</li></ul><h5><strong>12:00 - 12:30 Multiomics in Laboratory Medicine</strong></h5><ul><li>David Friedecký</li></ul><h5><strong>12:30 - 12:50 Back to the Old Masters of Lacquerware: Classification of Asian Lacquers Using Atmospheric Solids Analysis Probe High-Resolution Tandem Mass Spectrometry</strong></h5><ul><li>Vojtěch Zemek</li></ul><h5><strong>12:50 - 13:10 Using Charge Detection Mass Spectrometry with an Electrostatic Linear Ion Trap for the Analysis of Viral Vectors and Large Protein Complexes</strong></h5><ul><li>Alex Muck (Waters)</li></ul><h5><strong>13:10 - 13:30 Pioneering 4D Multiomics and Functional Proteomics/Matbolomics 2.0</strong></h5><ul><li>Daniel Vláčil (Bruker)</li></ul><h5><strong>13:30 - 15:00 </strong>Lunch</h5><h5><strong>15:00 - 18:00 Social/sport event</strong></h5><h5><strong>19:00 - ???&nbsp;Social dinner (Faculty of Science, foyer, 6th floor)</strong></h5><h4><strong>Thursday 18th June 2026</strong></h4><h5><strong>8:30 – 9:00 Breakfast (Faculty of Science, foyer, 2nd floor), installation of posters (Faculty of Science, seminary rooms, 2nd floor)</strong></h5><h5><strong>9:00 – 9:30 Capillary Electrophoresis - Mass Spectrometry for the characterization of proteoforms on the intact level</strong></h5><ul><li>Christian Neusüß</li></ul><h5><strong>9:30 – 10:00 Investigation of acid-base and electromigration properties of biopeptides by capillary electrophoresis</strong></h5><ul><li>Václav Kašička</li></ul><h5><strong>10:00 – 10:20 FromTissue to Single Cells: Targeted Hormonomics in Root Protoplasts</strong></h5><ul><li>Ondřej Novák</li></ul><h5><strong>10:20 – 10:40 Three-level Microfluidic Architecture as a Framework for Modular Analytical Instrumentation</strong></h5><ul><li>Kateryna Trach</li></ul><h5><strong>10:40 – 11:00&nbsp;Optimizing Gradient Conditions in Comprehensive 2D Liquid Chromatography: A Comparison of Chromatographic Response Functions</strong></h5><ul><li>Petr Česla</li></ul><h5><strong>11:00 - 11:30 </strong>Coffee break</h5><h5><strong>11:30 - 12:00 Open-source capillary electrophoresis - democratizing separation science: Design principles and practical implementations from our laboratory</strong></h5><ul><li>Petr Kubáň</li></ul><h5><strong>12:00 - 12:30 Analysis of biomedical, environmental and pharmaceutical samples by microchip electrophoresis</strong></h5><ul><li>Marián Masár</li></ul><h5><strong>12:30 - 13:00 UV-LED coupling for high-sensitivity glycan analysis in commercial capillary electrophoresis system</strong></h5><ul><li>Jana Lavická</li></ul><h5><strong>13:30 - 14:00 Closing of the conference and farewell drink (Faculty of Science, foyer, 2nd floor)</strong></h5><h5><strong>14: 00 - 15:00 &nbsp;&nbsp;&nbsp; </strong>Lunch</h5><h3><strong>Sponsors &amp; Partners</strong></h3><h5><strong>Organizers</strong></h5><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/341"><strong>Department of Analytical chemistry, Faculty of Science, Palacky University</strong></a></li><li>Faculty of Science, Palacky University</li></ul><h5><strong>Co-organizers</strong></h5><ul><li>ARTECA</li><li>Fort Science</li><li>SMALT</li><li>OSCHE ČSCH</li><li>Czech Chemical Society (ČSCH)</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/companies/21"><strong>Czech Society for Mass Spectrometry (CSMS)&nbsp;</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/1"><strong>LabRulez</strong></a></li></ul><h5><strong>Sponsors</strong></h5><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/companies/37"><strong>Altium International s.r.o. (HPST)</strong></a></li><li>Alven Laboratories</li><li>AMEDIS</li><li>Bruker</li><li>GALOCHROM</li><li>Chromservis</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/companies/176"><strong>Metrohm Česká republika</strong></a></li><li>Merck</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/168"><strong>ECOM</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/51"><strong>Phenomenex</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/companies/42"><strong>Pragolab</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/companies/43"><strong>Shimadzu Handels GmbH</strong></a></li><li>TAPI</li><li>Teva</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/companies/50"><strong>Waters Gesellschaft m.b.H.</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/59"><strong>Watrex</strong></a></li></ul>

Advances in Chromatography and Electrophoresis & Chiranal 2026 - Programme

<h3><strong>Introduction</strong></h3><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_From_Raw_Signals_to_Reliable_Results_Post_Acquisition_Data_Workflows_in_ICP_Analysis_f7248bb920.jpg" alt="Thermo Fisher Scientific: From Raw Signals to Reliable Results: Post-Acquisition Data Workflows in ICP Analysis" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_From_Raw_Signals_to_Reliable_Results_Post_Acquisition_Data_Workflows_in_ICP_Analysis_f7248bb920.jpg 245w," sizes="100vw" width="1024" height="512"></p><p>Modern elemental analysis techniques such as ICP-OES and ICP-MS are capable of generating large volumes of highly sensitive, multi-dimensional data in a single analytical run. These technologies are widely used across environmental, pharmaceutical, food, and materials science applications due to their precision and low detection limits. However, while significant emphasis is often placed on method development, instrument optimisation, and sample preparation, the true scientific value of any analysis is ultimately determined during the post-acquisition phase. It is here that raw instrumental signals are processed, interrogated, and validated before being translated into meaningful and defensible results. Whether you are working with the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products?category=227&amp;instrumentationItems=84&amp;manufacturerItems=3&amp;search=iCAP+PRO"><strong>iCAP PRO ICP-OES</strong></a>, the&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products?category=232&amp;manufacturerItems=3&amp;search=iCAP+MX"><strong>iCAP MX ICP-MS</strong></a>, the iCAP 7000 OES, or Qnova ICP-MS systems, the interface and workflow logic remain familiar.</p><h3><strong>Method</strong></h3><p>Following data acquisition, analysts must first navigate and organise <strong>complex datasets</strong> efficiently. Large analytical sequences may contain hundreds of samples, each with multiple analytes, replicates, and quality control elements. Tools such as column sorting and filtering are therefore essential for structured data interrogation. Sorting concentration values, for example, allows rapid identification of extreme values or potential outliers, while filtering by sample type, QC category, or analyte enables targeted investigation of specific data subsets. These tools support not only workflow efficiency but also statistical awareness, helping analysts detect trends, inconsistencies, or anomalies that may otherwise go unnoticed. In parallel, maintaining a complete <strong>LabBook</strong> history ensures that all changes to methods, calibration parameters, and analytical settings are recorded. This level of traceability is essential for regulatory compliance, particularly in environments operating under ISO standards or Good Laboratory Practice, and it ensures that results can be reproduced and audited with confidence.</p><p>A fundamental aspect of post-acquisition processing is the <strong>application and evaluation of correction models</strong>. ICP-based techniques are inherently susceptible to a range of <strong>interferences</strong>, including <strong>background signals, spectral overlaps, and matrix-induced signal suppression or enhancement</strong>. Blank subtraction is typically the first correction applied, removing contributions from reagents, solvents, and instrument background. By comparing results with and without blank correction, analysts can assess the significance of background contributions, particularly at low concentration levels. In ICP-OES, Inter-element correction (IEC) addresses spectral interferences by mathematically compensating for overlapping emission lines, which is especially important in complex matrices containing multiple elements.&nbsp;For ICP-MS, correction equations can be similarly implemented to correct for the presence of an isobaric interferences of mass signals.</p><p><strong>Internal standard (IS) correction</strong> is another critical component, used to normalise signal fluctuations caused by instrument drift, variations in sample introduction, or matrix effects. Reviewing data with these corrections toggled on and off provides valuable diagnostic insight, allowing analysts to determine whether corrections are appropriate and whether the underlying method is robust.</p><p>While processed concentration data is the primary output of most analyses, deeper insight can be gained by examining the <strong>underlying signal intensities</strong>. Replicate measurements, for instance, provide a direct assessment of analytical precision. Consistent replicate signals indicate stable measurement conditions, whereas significant variation may suggest issues such as sample heterogeneity, nebuliser instability, or matrix interference. Similarly, blank intensities can reveal contamination or insufficient rinsing between samples, often serving as an early indicator of systematic error. In ICP-OES, spectral <strong>sub-array views</strong> allow analysts to visualise the emission profile around a selected wavelength, enabling verification of peak shape, background correction points, and potential spectral overlaps. In <strong>ICP-MS</strong>, attention must be given to <strong>detector behaviour</strong>, particularly when signals transition between pulse and analog modes at higher concentrations. Such transitions can introduce non-linearity into calibration curves, sometimes necessitating cross-calibration to maintain quantitative accuracy.</p><p><strong>Calibration </strong>is central to transforming raw signal intensity into quantitative concentration data, and its evaluation is one of the most critical steps in the workflow. Several performance indicators are used to <strong>assess calibration quality</strong>. The <strong>coefficient of determination</strong> (<strong>R²</strong>) provides a measure of how well the calibration model fits the data, though a high R² alone does not guarantee accuracy. Bias offers insight into systematic deviations between expected and measured values, highlighting potential issues with standards or instrument response. <strong>Detection limits</strong>, including the <strong>limit of detection </strong>(<strong>LOD</strong>) and<strong> instrument detection limit</strong> (<strong>IDL</strong>), define the sensitivity of the method, while <strong>background equivalent concentration</strong> (<strong>BEC</strong>) reflects the contribution of background signal to the overall measurement. A comprehensive calibration assessment requires consideration of all these parameters together, rather than reliance on a single metric. In addition, quality control samples—such as <strong>calibration check standards </strong>(<strong>CCVs</strong>),<strong> certified reference materials</strong> (<strong>CRMs</strong>), and <strong>matrix spikes</strong>—are used to verify accuracy and method performance. Automated flagging of QC results that fall outside predefined acceptance criteria provides an efficient means of identifying non-compliant data and supports rapid decision-making.</p><p>Equally important is the <strong>evaluation of instrument performance</strong> through diagnostic readbacks recorded during the analysis. These parameters provide insight into the physical and operational state of the instrument at the time of measurement. For<strong> ICP-MS</strong>, key readbacks include <strong>nebuliser gas pressure, vacuum levels, and interface conditions</strong>. Changes in these parameters can indicate issues such as partial blockages, salt deposition, or vacuum degradation. <strong>Similarly, plasma-related parameters and gas flow stability</strong> are critical indicators in <strong>both ICP-OES and ICP-MS systems</strong>. By correlating readback trends with analytical results, analysts can identify the root causes of anomalies, distinguish between instrument-related and sample-related issues, and take corrective action where necessary. This diagnostic capability is particularly valuable when troubleshooting unexpected results or when sharing data with technical support teams for further investigation.</p><p>Once the data has been thoroughly reviewed and validated, the <strong>final step is to export and communicate the results </strong>in a clear and usable format. Structured reporting tools enable the generation of comprehensive summaries that include concentration data, calibration details, quality control results, and any associated flags or annotations. These reports are essential for documentation, regulatory submissions, and communication with stakeholders. For greater flexibility, exporting data in CSV format allows integration with external tools such as spreadsheet software, statistical analysis platforms, or laboratory information management systems (LIMS). This interoperability facilitates advanced data analysis, long-term data storage, and seamless integration into broader laboratory workflows.</p><h3><strong>Conclusion</strong></h3><p>In conclusion, post-acquisition data processing is not merely a procedural step but a critical component of the analytical workflow that determines the reliability and scientific validity of results. Through careful organisation of data, rigorous application of correction models, detailed evaluation of calibration performance, and continuous monitoring of instrument diagnostics, analysts can ensure that their results are both accurate and defensible. As analytical technologies continue to evolve and datasets become increasingly complex, the importance of robust and systematic data evaluation will only grow. Mastery of these workflows transforms raw instrumental signals into high-quality scientific information, underpinning confident decision-making across a wide range of applications.</p><h3><strong>Acknowledgement</strong></h3><p>I would like to thank&nbsp;<strong>Matthew Gregory&nbsp;</strong>Field Applications Scientist, North EMEA, Trace Elemental Analysis and&nbsp;<strong>David Fishwick&nbsp;</strong>Field Applications Scientist, North EMEA, Trace Elemental Analysis for the support on this blog and the webinars.</p><p>Sign up for our webinars live and on demand.</p><p><strong>English</strong></p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/5795"><strong>Lunch and Learn Tips and Tricks Series: Qtegra Part 1</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/5976"><strong>Lunch and Learn Tips and Tricks Series: Qtegra Part 2</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/5977"><strong>Lunch and Learn Tips and Tricks Series: Trace Elemental Analysis (ICP-OES &amp; ICP-MS)</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/5978"><strong>Trace Elemental Analysis: Ask the Expert</strong></a></li></ul><p><strong>Deutsch</strong></p><ul><li><strong>19. März 2026</strong><br><a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/wcc/r/5179134/393E071E3B501943730958BA6203F477">Interne Standards in der ICP-OES: Ein Praxisguide für zuverlässige Qualitätssicherung im Labor</a></li><li><strong>18. Juni 2026</strong><br><a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/wcc/r/5179292/AE4C576B6A54D1AC182F7F77573D380F">Fehler reduzieren, Durchsatz steigern: Autoverdünnung mit PrepFast am ICP-MS</a></li><li><strong>17. September 2026</strong><br><a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/wcc/r/5179423/B5019C560431BADCA2A76E54E4EFE56F">ICP-OES smarter nutzen: Probendurchsatz erhöhen, Ressourcen sparen</a></li><li><strong>17. Dezember 2026</strong><br><a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/wcc/r/5179530/94EEDD1F56138F5EEE2AF24E29E6C12A">Qtegra ISDS Software Unlocked – Live im Expertengespräch</a></li></ul><blockquote><p><strong>Visit us on&nbsp;</strong><a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/"><strong><u>LinkedIn:</u></strong></a><strong>&nbsp;</strong>#AnalyticalChemistry #ICPMS #ICPOES #DataAnalysis</p></blockquote>

From Raw Signals to Reliable Results: Post-Acquisition Data Workflows in ICP Analysis

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 18th May 2026? Check out new documents from the field of spectroscopy/spectrometry and related techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><strong>LabRulezGCMS</strong></a> libraries.</p></blockquote><p>This week we bring you brochure by<strong> MILESTONE </strong>and<strong> </strong>application notes by<strong> Shimadzu </strong>and <strong>Thermo Fisher Scientific!</strong></p><h3><strong>1. MILESTONE: </strong><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?search=ETHOS+LEAN+"><strong>ETHOS™ LEAN</strong></a><strong> Compact Microwave Labstation</strong></h3><ul><li>Brochure</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/Brochure_ETHOS_LEAN_1_c80f4403a4.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Sample preparation is the foundation of many analytical workflows, and often the most critical step. In elemental analysis, proper digestion ensures accurate and reproducible results with AAS, ICP, and ICP-MS by enabling complete recovery of target elements, minimizing interferences, and reducing blanks. With over 35 years of innovation and more than 30,000 microwave systems installed worldwide, Milestone is a global leader in microwave sample preparation. The ETHOS LEAN, now in its 2nd series, represents this expertise: a compact, affordable labstation delivering full digestion capabilities without compromise. Beyond digestion, ETHOS LEAN supports solvent extraction for chromatography, solvent-free extraction of natural products, and even microwave synthesis workflows, offering unmatched versatility in its class. Selecting the right system is more than a purchase decision: it’s choosing a partner. With Milestone, you gain not only proven technology but also the knowledge and support to ensure long-term success.</p><h4><strong>BUILT FOR MORE THAN DIGESTION</strong></h4><p><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?search=ETHOS+LEAN+"><strong>ETHOS LEAN</strong></a> goes beyond digestion. As a compact Microwave Labstation, it supports a suite of accessories that expand its capabilities into multiple workflows. Microwave technology provides a faster, cleaner, and more efficient alternative to conventional sample preparation techniques, reducing processing time, simplifying operations, and minimizing reagent consumption.&nbsp;</p><h5><strong>Solvent extraction</strong></h5><p>Closed-vessel microwave technology streamlines extraction for chromatographic analysis, dramatically reducing solvent use and cutting analysis times. Ideal for organic pollutant extraction from environmental samples or fat determination in food and feed.</p><h5><strong>Solvent-free extraction</strong></h5><p>Patented Milestone technology enables fast and efficient essential oil extraction in just minutes, preserving aroma and natural composition while minimizing degradation. Selective heating promotes a quicker, more efficient release from plant cells.</p><h5><strong>Microwave synthesis</strong></h5><p>Microwave synthesis is a safer and faster alternative to heating mantles or complex reactors, enabling rapid optimization of conditions. Its speed supports research projects and allows practical teaching sessions within standard class times.</p><h5><strong>High-temperature processes</strong></h5><p>With the ultraFAST accessory, ETHOS LEAN reaches 1200 °C in just minutes, transforming into a microwave furnace for demanding high-temperature applications such as inorganic synthesis, fusion, or fire assay.</p><h3><strong>2. Shimadzu: Discriminating between Microsamples of Similar Resins with a Combination of FTIR and Thermal Analysis Instruments</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_01114_en_a9291de45e.pdf"><strong>Full PDF for download</strong></a></li></ul><h4><strong>User Benefits</strong></h4><ul><li>Using the ATR method with FTIR spectroscopy enables simple and rapid qualitative analysis of polymers.</li><li>DSC analysis may be able to reveal differences in polymer thermal histories that cannot be confirmed by FTIR alone.</li><li>TG-DTA can be used to confirm the content level of inorganic additives in polymers</li></ul><p>A wide range of polymer resins is used in modern society for diverse applications, resulting in increasing demand for qualitative analysis of resin microsamples, such as identifying resin contaminants in products or qualitatively evaluating microplastics for environmental impact assessments. FTIR spectrophotometers are commonly used for qualitative analysis of polymers. In particular, the ATR (attenuated total reflectance) method is widely used because measurements can be performed simply and quickly by clamping a sample against a prism to ensure close contact.&nbsp;</p><p>While the ATR method makes it relatively easy to discriminate between different types of polymers, clear differences may not appear when analyzing similar polymers—for example, when there are only slight differences in the type or content of additives or the thermal histories during manufacturing. In such cases, differences may be confirmed by using thermal analysis instruments, such as a DSC or TG-DTA system.&nbsp;</p><p>This article describes an example in which three instruments— an <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=1&amp;search=IRSpirit-TX"><strong>IRSpirit-TX</strong></a> FTIR spectrophotometer, a <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=1&amp;search=DSC-60+Plus"><strong>DSC-60 Plus</strong></a> differential scanning calorimeter, and a DTG-60 simultaneous DTA-TG unit (Fig. 1)—were used to confirm differences among six microsamples of polypropylene (PP) resin.</p><h4><strong>Conclusion</strong></h4><p>Details of the six types of PP resin identified from the above measurement results are shown in Table 4. The results indicate that by using an FTIR spectrophotometer in combination with thermal analysis equipment, such as DSC and TG-DTA systems, it is possible to distinguish between minute amounts of the same type of resin with various different properties.</p><h3><strong>3. Thermo Fisher Scientific: XPS depth profiling of advanced solar cells with femtosecond laser ablation</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/xps_depth_profiling_advanced_solar_cells_appnote_7bda4471a5.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Perovskites are an emerging class of materials in the solar cell industry, exhibiting a number of promising properties, such as improved efficiency and weight, compared to traditional silicon-based devices. X-ray photoelectron spectroscopy (XPS) is an established tool in solar cell research due to its ability to provide extremely surface-sensitive information about elemental composition along with chemical and electronic states.¹ XPS is ultimately a surface analysis technique, however, and in order to assess the full composition of complex, multi-layered structures such as solar cells, a technique known as depth profiling is necessary, which performs multiple rounds of successive material removal and analysis.&nbsp;</p><p>This application note explores a recent study by Chandler et al. that focuses on solar cells designed for aerospace applications,² where accurate determination of the “true” starting composition of the stacks is essential for tests that simulate space conditions, such as radiation exposure. Without a reliable baseline, it becomes impossible to distinguish between changes induced by the experimental conditions and artifacts introduced during analysis. Conventional ion beam sputtering methods used for depth profiling are known to distort chemical information for perovskites; femtosecond laser ablation (fs-LA) is presented as a novel, alternative method that helps to preserve vital chemical information.</p><h4><strong>Experimental</strong></h4><p>A halide-perovskite-based solar cell was fabricated on an ITO/SnO₂ substrate using a spin coating method; the structure of the layers is shown in Figure 1.</p><p>Analysis was performed with the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2206"><strong>Thermo Scientific™ Hypulse™ Surface Analysis System</strong></a>, which is equipped with both traditional ion-beam sputtering and femtosecond-laser ablation capabilities. XPS data was collected in SnapShot acquisition mode using an X-ray spot size of 30-200 µm, depending on the method of depth profiling.&nbsp;</p><p>A MAGCIS ion gun was employed for the sputter depth profiles, generating either a 500 eV monatomic Ar⁺ beam or 8 keV Ar₁₅₀⁺ clusters. The fs-LA depth profiles were generated using a 1,030 nm wavelength laser operating at a 160 fs pulse length. The pulse energy was increased from 42 µJ to 167 µJ when transitioning from the perovskite layer into the substrate structure. A flood gun was employed for charge neutralization during profiling.</p><h4><strong>Summary&nbsp;</strong></h4><p>This study confirms the challenges associated with traditional ion sputtering (both monatomic and cluster) for the depth profiling of perovskite-based solar cells. These methods cause preferential sputtering, particularly of lighter elements like carbon, nitrogen, and iodine, which distorts elemental ratios in the profiles and results in artificial signals, such as the formation of metallic lead (Pb⁰). Depth profiling with femtosecond laser ablation represents a novel and robust alternative that preserves the original chemical composition and oxidation states throughout the perovskite layer. By avoiding preferential removal effects, accurate compositional information is maintained during the profile, and erroneous peak signals associated with chemical reduction are eliminated. These factors are vital in establishing a chemically undisturbed baseline before performing tests that simulate environmental effects on the solar cells.&nbsp;</p><p>With fs-LA depth profiling, any induced changes can be confidently delineated from analytical artifacts, and researchers can better understand and mitigate environmental effects on solar-cell performance, eventually leading to improved solar technologies for aerospace applications.</p>

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Thermo Scientific Neoma MS/MS MC-ICP-MS

The Neoma MS/MS MC-ICP-MS is the first dedicated collision/reaction cell MC-ICP-MS with unique pre-cell mass filtering technology, allowing you to separate out isobaric interferences.

<div><div id="product-description"><p><strong>Separate out isobaric interferences to achieve new levels of precision and accuracy in your isotope research. There are some situations when even the highest resolution is not enough and isobaric interferences cannot be resolved, even with the best ICP-MS instruments available. Thermo Scientific™ Neoma™ MS/MS MC-ICP-MS provides the solution.</strong></p><p>The Neoma MS/MS MC-ICP-MS is the first dedicated collision/reaction cell MC-ICP-MS with unique pre-cell mass filtering technology, allowing you to separate out isobaric interferences and opening up new avenues in the field of laser ablation MC-ICP-MS and beyond.</p></div><div><h3><strong>Modes</strong></h3><ul><li><strong>Full transmission mode:</strong> High-precision isotope analysis without utilizing the collision/reaction cell technology. Additionally, the pre-cell mass filter can be used to remove matrix elements, boosting sensitivity and improving abundance sensitivity.</li><li><strong>Collision/reaction cell mode:</strong> For isotope systems with significant isobaric interferences, patented pre-cell mass filter technology removes matrix elements that might act to cause secondary reactions in the CRC.</li></ul><figure class="image"><img style="aspect-ratio:650/468;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Neoma_MS_MS_MC_ICP_MS_0986e1671d.jpg" alt="Thermo Scientific™ Neoma™ MS/MS MC-ICP-MS." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Neoma_MS_MS_MC_ICP_MS_0986e1671d.jpg 217w," sizes="100vw" width="650" height="468"></figure><h3><strong>Applications</strong></h3><ul><li><strong>In-situ Rb-Sr dating:</strong> Unprecedented precision for dating geological samples by a combination of the pre-cell mass filter, the collision/reaction cell and the multicollector detector array.</li><li><strong>Interference-free Ti isotope analysis:</strong> The pre-cell mass filter can be used to remove molecular and doubly charged interferences, and the collision/reaction cell can be used to remove isobaric interferences.</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_001006_sr_ioms_b_isotopes_an001006_en_90167475a4.pdf"><strong>In-situ boron isotope analysis of biogenic carbonates</strong></a>: Unprecedented accuracy LA-MC-ICP-MS analysis by using the pre-cell mass filter to remove interferences from scattered Ca<sup>4+</sup> ions on <sup>10</sup>B</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_001035_ioms_mc_icp_ms_neoma_potassium_an001035_em_en_913d82d28d.pdf"><strong>K isotope analysis</strong></a>: Interference of <sup>40</sup>Ar<sup>+</sup> can hamper the precision and accuracy of the K isotope analysis. Remove the <sup>40</sup>Ar<sup>+</sup> interference with either: (1) the <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/order/catalog/product/BRE0014262">eXtra High Resolution (XHR)</a> of Neoma MC-ICP-MS, or (2) for smaller sample sizes, the use of H<sub>2</sub> and He in the collision/reaction cell to neutralize <sup>40</sup>Ar and <sup>40</sup>ArH</li></ul><h3><strong>Technology options</strong></h3><ul><li><strong>Extended choice with 24 amplifier array:</strong> Ion current amplifiers are mounted in a doubly shielded, evacuated and thermostatted housing with a temperature stability of 0.01°C/hour, to guarantee baseline and gain stability.</li><li><strong>Enhanced variable detector array:</strong> Precise alignment of all 11 cups with ion beams of different dispersions to ensure the flexibility to cover isotopic applications from Li through to U, in low or high resolution, and without compromising the native dispersion of the mass analyzer.</li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/order/catalog/product/BRE0025160"><strong>Jet Interface</strong></a>: The Jet Interface, in combination with a desolvating nebulizer system, increases sensitivity by 10 to 20 times compared to standard wet plasma.</li><li><strong>Choice of resolution:</strong> 3 different mass resolutions for maximizing the sensitivity of your analysis whilst allowing interferences to be resolved.</li><li><strong>Flexibility of detector types:</strong> A flexible, three-detector system spanning &gt;9 orders of magnitude in signal intensity range (1 cps – 6 Gcps). The central channel is equipped with a dual-mode detector that can be switched from Faraday cup to SEM ion counter, and with the proprietary relay matrix, any amplifier can be assigned to any of the Faraday cups via software.</li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/order/catalog/product/IQLAAMGAATFAPTMZZZ"><strong>10<sup>13</sup>Ω amplifier technology</strong></a>: Ensures fast response times with extremely low noise characteristics. The benefits of Faraday cups can be realized at low signal intensities (30 kcps – 3 Mcps), delivering external precisions that approach the ultimate limits of counting statistics.</li></ul></div></div>

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