ACETIC ACID ANALPURE®

Importance of the topic

High-purity reagents are critical for reliable analytical measurements, chemical synthesis, and quality control. Acetic acid of analytical grade purity ensures minimal interference from impurities in sensitive assays, instrumental techniques, and regulatory analyses.

Objectives and Overview of the Certificate

This document verifies the chemical and trace-metal purity of Acetic Acid ANALPURE® (batch 5022), confirming its suitability for laboratory and industrial use. It presents specification limits, actual measured values, and compliance with established quality standards.

Methodology and Analytical Procedures

The following tests were employed to assess purity:

• Colour measurement by APHA method
• Titrimetric assay to determine acetic acid content
• Reactivity tests with permanganate and dichromate to detect reducing substances
• Anion quantification for chloride, phosphate, and sulfate
• Trace metal analysis for over 50 elements at low ppb levels

Used Instrumentation

Although specific instruments were not explicitly listed, standard practice for this certificate likely involved:

• UV-visible spectrophotometer for colour (APHA) determination
• Automatic titrator for assay of acetic acid
• Ion chromatography or ion-selective electrodes for anion analysis
• Inductively coupled plasma mass spectrometry (ICP-MS) for multi-element trace impurity profiling

Main Results and Discussion

All measured parameters met or exceeded specification limits:

• Colour: <10 APHA units (limit: 10)
• Chloride, phosphate: <1 ppm each
• Sulfate: <0.5 ppm
• Assay: 99.7% acetic acid
• Reducing substances: passes both permanganate and dichromate tests
• Trace metals: the vast majority of elements were below 0.1–0.5 ppb, well within maximum allowable concentrations

The low levels of common cations (Ca, K, Na, Mg, Mn) reflect effective purification, though slight increases may occur over time when stored in glass.

Benefits and Practical Applications

This high-purity acetic acid supports:

• Accurate quantitative and qualitative chemical analyses in environmental, pharmaceutical, and food labs
• High-precision synthetic chemistry where metal or anion contaminants can inhibit catalysts
• Quality assurance in industrial processes requiring defined reagent specifications

Future Trends and Potential Applications

Advancements may include:

• In-line monitoring of reagent purity using real-time spectroscopy or electrochemical sensors
• Green purification techniques to reduce energy consumption and solvent waste
• Integration of blockchain or digital twins to track reagent quality from production to end-use

Conclusion

The certificate confirms that Acetic Acid ANALPURE® batch 5022 meets stringent purity requirements across colour, assay, anions, and trace metals. Its compliance ensures dependable performance in diverse analytical and industrial applications.

Reference

Analytika, spol. s r.o. Certificate of Analysis for Acetic Acid ANALPURE®, Batch 5022, Release Date: 05.05.2022