1. KONFERENCE ČESKÉ SPOLEČNOSTI PRO HMOTNOSTNÍ SPEKTROMETRII - Sborník abstraktů

Significance of Next-Generation Mass Spectrometers

Thermo Fisher Scientific’s latest mass spectrometry platforms build on proven performance to address demanding analytical challenges. By combining high resolution, mass accuracy, sensitivity and workflow flexibility, these instruments help researchers tackle complex samples, speed method development and gain confidence in both qualitative and quantitative results.

Product Highlights

• Orbitrap Elite Hybrid LC-MS: Industry-leading resolving power up to 240,000 and sub-ppm mass accuracy for top-down proteomics, small-molecule identification and PTM mapping.
• Q Exactive™ Benchtop Orbitrap: Integrated quadrupole-Orbitrap design delivers high-resolution, accurate-mass data simultaneously for qualitative and quantitative assays, streamlining workflow for metabolomics and drug discovery.
• Velos Pro Ion Trap: Fast scan speeds and high sensitivity with High-Energy Collisional Dissociation (HCD) fragmentation for in-depth proteomic and small-molecule characterization.
• TSQ Quantum XLS Ultra GC-MS/MS: Robust triple quadrupole for selective reaction monitoring in pesticide, environmental and forensic testing with superior sensitivity in both GC and LC modes.

Key Features and Benefits

• High Speed Analysis: Rapid data acquisition accelerates sample throughput, enabling large-scale studies.
• Enhanced Confidence: Unprecedented resolution and mass accuracy improve compound identification and minimize false positives.
• Versatile Workflows: Configurable platforms support proteomics, metabolomics, food safety, clinical research and more.
• Seamless Integration: Intuitive software interfaces and open access architecture streamline method development and data processing.

Applications and Use Cases

These instruments excel in top-down and bottom-up proteomics, comprehensive small-molecule profiling, targeted quantitation of environmental contaminants, biomarker discovery and clinical diagnostics. Their combined capabilities support research from fundamental biology to regulated laboratory environments.

Conclusion

Thermo Fisher’s new mass spectrometry line delivers the speed, sensitivity and accuracy needed for today’s most challenging analyses. With scalable platforms and integrated workflows, researchers are well equipped to accelerate discovery and confidently characterize complex samples.