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Application NoteBiopharmaceuticalsCharacterization of Protein ThermalStability Using UV-Vis SpectroscopyBenefits of the Agilent Cary 3500UV‑Vis spectrophotometer with a Peltiertemperature‑controlled multicell in proteintherapeutic researchAuthorsCarlos Santos MartinLa Trobe Institute forMolecular Science (LIMS),La Trobe University,Melbourne, Victoria 3086,AustraliaBiswaranjan MohantySydney Analytical CoreResearch Facility,The University of Sydney,Sydney, New...
Key words
protein, proteintemperature, temperaturespectrophotometer, spectrophotometerpeltier, peltierabsorbance, absorbancethermal, thermaldsba, dsbameasure, measurederivative, derivativestability, stabilitysmoothing, smoothingmulticell, multicellvis, viscuvette, cuvetteecdsba
Application NotePharmaceuticalsParallel Synthesis andCharacterization of a ChitosanDrug Carrier SystemCary 3500 Peltier UV-Vis spectrophotometer usedto monitor cross-linking mechanismIntroductionAuthorDr. Mohammad Al KobaisiDr. Matthew Quinn12Swinburne University ofTechnology, School ofScience, Faculty of ScienceEngineering and Technology,Melbourne, Australia1Agilent Technologies, Inc.Melbourne, Australia2Stable, controllable, and biocompatible drug carrier...
Key words
chitosan, chitosanopp, oppoctaphosphonate, octaphosphonatefitc, fitccross, crosstetraphenyl, tetraphenylhydrogel, hydrogelchanges, changeslinking, linkingfluorescein, fluoresceinwavelength, wavelengthisothiocyanate, isothiocyanatesynthesis, synthesisvol, volcromophor
White PaperBest Practice for Nucleic AcidThermal Stability MeasurementsUsing the Cary 3500 UV-VisSpectrophotometerThermal melt (Tm) analysis using rapid, precisetemperature-dependent UV-Vis absorbancemeasurementsThe Cary 3500 Peltier UV-Vis systems offer the ability to analyze the thermalstability and profiles of biological and other molecules usingtemperature‑controlled...
Key words
cuvette, cuvettetemperature, temperaturepeltier, peltierprobe, probeblock, blocknucleic, nucleiccuvettes, cuvettesmelting, meltingstirring, stirringsample, samplethermal, thermalstranded, strandedoptimize, optimizeinterval, intervalmelt
Application NoteBiopharma/PharmaCharacterization of Antibody-DrugConjugate Critical Quality AttributesUsing the Agilent Cary 3500 UV-VisMultizone Temperature CapabilityAuthorsAveline Neo andSuresh Babu C.V.Global Solution DevelopmentCenterAgilent TechnologiesSingapore (Sales) Pte Ltd.AbstractAntibody-drug conjugates (ADCs) are a growing class of biotherapeutics. Duringmanufacturing, it is important to monitor critical quality...
Key words
dar, daraggregation, aggregationadc, adcindex, indexherceptin, herceptinabsorbance, absorbanceadcs, adcsmultizone, multizoneantibody, antibodycytotoxic, cytotoxicvis, visscan, scanspectrophotometer, spectrophotometerconjugated, conjugatedanalog
 

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Application NoteBiopharmaceuticalsCharacterization of Protein ThermalStability Using UV-Vis SpectroscopyBenefits of the Agilent Cary 3500UV‑Vis spectrophotometer with a Peltiertemperature‑controlled multicell in proteintherapeutic researchAuthorsCarlos Santos MartinLa Trobe Institute forMolecular Science (LIMS),La Trobe University,Melbourne, Victoria 3086,AustraliaBiswaranjan MohantySydney Analytical CoreResearch Facility,The University of Sydney,Sydney, New...
Key words
protein, proteintemperature, temperaturespectrophotometer, spectrophotometerpeltier, peltierabsorbance, absorbancethermal, thermaldsba, dsbameasure, measurederivative, derivativestability, stabilitysmoothing, smoothingmulticell, multicellvis, viscuvette, cuvetteecdsba
Application NotePharmaceuticalsParallel Synthesis andCharacterization of a ChitosanDrug Carrier SystemCary 3500 Peltier UV-Vis spectrophotometer usedto monitor cross-linking mechanismIntroductionAuthorDr. Mohammad Al KobaisiDr. Matthew Quinn12Swinburne University ofTechnology, School ofScience, Faculty of ScienceEngineering and Technology,Melbourne, Australia1Agilent Technologies, Inc.Melbourne, Australia2Stable, controllable, and biocompatible drug carrier...
Key words
chitosan, chitosanopp, oppoctaphosphonate, octaphosphonatefitc, fitccross, crosstetraphenyl, tetraphenylhydrogel, hydrogelchanges, changeslinking, linkingfluorescein, fluoresceinwavelength, wavelengthisothiocyanate, isothiocyanatesynthesis, synthesisvol, volcromophor
White PaperBest Practice for Nucleic AcidThermal Stability MeasurementsUsing the Cary 3500 UV-VisSpectrophotometerThermal melt (Tm) analysis using rapid, precisetemperature-dependent UV-Vis absorbancemeasurementsThe Cary 3500 Peltier UV-Vis systems offer the ability to analyze the thermalstability and profiles of biological and other molecules usingtemperature‑controlled...
Key words
cuvette, cuvettetemperature, temperaturepeltier, peltierprobe, probeblock, blocknucleic, nucleiccuvettes, cuvettesmelting, meltingstirring, stirringsample, samplethermal, thermalstranded, strandedoptimize, optimizeinterval, intervalmelt
Application NoteBiopharma/PharmaCharacterization of Antibody-DrugConjugate Critical Quality AttributesUsing the Agilent Cary 3500 UV-VisMultizone Temperature CapabilityAuthorsAveline Neo andSuresh Babu C.V.Global Solution DevelopmentCenterAgilent TechnologiesSingapore (Sales) Pte Ltd.AbstractAntibody-drug conjugates (ADCs) are a growing class of biotherapeutics. Duringmanufacturing, it is important to monitor critical quality...
Key words
dar, daraggregation, aggregationadc, adcindex, indexherceptin, herceptinabsorbance, absorbanceadcs, adcsmultizone, multizoneantibody, antibodycytotoxic, cytotoxicvis, visscan, scanspectrophotometer, spectrophotometerconjugated, conjugatedanalog
 

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