Library | LabRulez ICPMS

AN INTEGRATED WORKFLOW FOR AUTOMATIC MAPPING OF DISULFIDE LINKAGES OF THERAPEUTIC PROTEINS USING HIGH-RESOLUTION LCMS, ETD FRAGMENTATION AND TARGETED INFORMATICS

Posters

| 2015 | Waters

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Waters

Industries

Clinical Research

Automated RapiFluor-MS Labeled Glycan Sample Preparation for Disulfide-Rich Glycoprotein

Applications

| 2021 | Waters

Sample Preparation, Consumables, HPLC

Instrumentation

Sample Preparation, Consumables, HPLC

Manufacturer

Waters

Industries

Pharma & Biopharma

Automated Disulfide Bond Mapping, and Comparing Innovator and Biosimilar mAbs Using UNIFI

Applications

| 2016 | Waters

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Waters

Industries

Pharma & Biopharma

Improving UPLC-FLR-MS N-glycan Analysis of Disulfide-rich Fusion Proteins Through Optimization of Sample Preparation

Applications

| 2021 | Waters

Sample Preparation, HPLC, LC/TOF, LC/HRMS, LC/MS

Instrumentation

Sample Preparation, HPLC, LC/TOF, LC/HRMS, LC/MS

Manufacturer

Waters

Industries

Proteomics

Disulfide Bond Characterization of Monoclonal Antibody (mAb) Using Q-TOF Mass Spectrometer

Applications

| 2019 | Shimadzu

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Shimadzu

Industries

Clinical Research

Bottom-up and Top-down Disulfide Bond Mapping of Beta-lactoglobulin on a Q-TOF with the Capability to Perform both CID and ECD

Posters

| 2022 | Agilent Technologies (ASMS)

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Agilent Technologies

Industries

Proteomics

Disulfide Bond Identification of Biotherapeutic Proteins Using Various Fragmentation Techniques Available on an Orbitrap Fusion Tribrid Mass Spectrometer

Posters

| 2016 | Thermo Fisher Scientific (ASMS)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Proteomics

Disulfide Bond and Glycosylation Site Occupancy Mapping of Trastuzumab Using a Novel Capillary MAbPac RP Column

Posters

| 2020 | Thermo Fisher Scientific (ASMS)

Consumables, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, LC columns

Instrumentation

Consumables, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, LC columns

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Characterization of Monoclonal Antibody Biosimilar through C-terminal and Disulfide Bond Peptides Sequencing Analysis on Q-TOF Mass Spectrometer

Applications

| 2020 | Shimadzu

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Shimadzu

Industries

Clinical Research

Confident peptide mapping and disulfide bond analysis of an IgG2 monoclonal antibody

Applications

| 2020 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Proteomics , Clinical Research

AN INTEGRATED WORKFLOW FOR AUTOMATIC MAPPING OF DISULFIDE LINKAGES OF THERAPEUTIC PROTEINS USING HIGH-RESOLUTION LCMS, ETD FRAGMENTATION AND TARGETED INFORMATICS

Automated RapiFluor-MS Labeled Glycan Sample Preparation for Disulfide-Rich Glycoprotein

Automated Disulfide Bond Mapping, and Comparing Innovator and Biosimilar mAbs Using UNIFI

Improving UPLC-FLR-MS N-glycan Analysis of Disulfide-rich Fusion Proteins Through Optimization of Sample Preparation

Disulfide Bond Characterization of Monoclonal Antibody (mAb) Using Q-TOF Mass Spectrometer

Bottom-up and Top-down Disulfide Bond Mapping of Beta-lactoglobulin on a Q-TOF with the Capability to Perform both CID and ECD

Disulfide Bond Identification of Biotherapeutic Proteins Using Various Fragmentation Techniques Available on an Orbitrap Fusion Tribrid Mass Spectrometer

Disulfide Bond and Glycosylation Site Occupancy Mapping of Trastuzumab Using a Novel Capillary MAbPac RP Column

Characterization of Monoclonal Antibody Biosimilar through C-terminal and Disulfide Bond Peptides Sequencing Analysis on Q-TOF Mass Spectrometer

Confident peptide mapping and disulfide bond analysis of an IgG2 monoclonal antibody

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