Applications - page 1

LC/UV/HRAM MS-based impurity profiling and structure elucidation of phosphoramidite raw materials used for oligonucleotide synthesis

Applications

| 2023 | Thermo Fisher Scientific

Software, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

Software, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Confident transformation site localization of PROTAC drug metabolites facilitated by multi-stage fragmentation LC-MS

Applications

| 2024 | Thermo Fisher Scientific

LC/MS, LC/HRMS, LC/MS/MS, LC/TOF

Instrumentation

LC/MS, LC/HRMS, LC/MS/MS, LC/TOF

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Confident and sensitive profiling of lipid nanoparticle raw materials and impurity identification using a LC/CAD/HRAM-MS method with inverse gradient

Applications

| 2023 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

A comprehensive software workflow for non-targeted analysis of per- and polyfluoroalkyl substances (PFAS) by high-resolution mass spectrometry (HRMS)

Applications

| 2023 | Thermo Fisher Scientific

Software, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

Software, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Environmental

Applying UHPLC-HRAM MS technology to characterize and quantify lipid components in vivo to support new LNP development

Applications

| 2022 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Comprehensive non-targeted workflow for confident identification of perfluoroalkyl substances (PFAS)

Applications

| 2025 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, Software

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, Software

Manufacturer

Thermo Fisher Scientific

Industries

Environmental

Characterization and quantification of lipid nanoparticle components and their impurities/degradants using an LC-HRAM MS platform

Applications

| 2021 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Lipidomics

Comprehensive PFAS screening in pharmaceutical packaging and medical devices by LC-HRAM-MS

Applications

| 2024 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Simultaneous Quantitation and Discovery analysis: Combining targeted and untargeted metabolomics on Orbitrap mass spectrometers

Applications

| 2026 | Thermo Fisher Scientific

LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS

Instrumentation

LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS

Manufacturer

Thermo Fisher Scientific

Industries

Metabolomics

Impurity profiling of mycophenolate mofetil using an Orbitrap Exploris 120 mass spectrometer and Vanquish Horizon UHPLC combined with Compound Discoverer software

Applications

| 2022 | Thermo Fisher Scientific

Software, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

Software, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma