Tips and tricks for LC–MS-based metabolomics and lipidomics analysis

Scientific articles
| 2024 | Czech Academy of Sciences
LC/MS, LC/MS/MS, LC/HRMS, LC/QQQ, LC/TOF, LC/Orbitrap, LC/IT, LC/QTRAP
Instrumentation
LC/MS, LC/MS/MS, LC/HRMS, LC/QQQ, LC/TOF, LC/Orbitrap, LC/IT, LC/QTRAP
Manufacturer
Agilent Technologies, Bruker, SCIEX, Waters, Thermo Fisher Scientific
Industries
Metabolomics, Lipidomics

Enhanced tissue compartmentalization by applying segmentation algorithms on reduced spatial omics data

Posters
| 2025 | Bruker (ASMS)
LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility, MALDI, MS Imaging
Instrumentation
LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility, MALDI, MS Imaging
Manufacturer
Bruker
Industries
Clinical Research

The timsTOF Ultra 2 enables systematic understanding of ubiquitination and degradation kinetics of degrader drug targets using slice-PASEF acquisition schemes

Posters
| 2025 | Bruker (ASMS)
LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility
Instrumentation
LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility
Manufacturer
Bruker
Industries
Proteomics

Studying protein-drug complexes under native conditions in the low nM range using MRMS

Applications
| 2020 | Bruker
LC/MS, LC/Ultra-HRMS
Instrumentation
LC/MS, LC/Ultra-HRMS
Manufacturer
Bruker
Industries
Clinical Research

Protein Clipping Variant Analysis of Vedolizumab using dedicated workflows in BioPharma Compass

Applications
| 2020 | Bruker
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
Instrumentation
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
Manufacturer
Bruker
Industries
Pharma & Biopharma

Tracking free-toxin distribution in xenografts after in-vivo ADC dosing by MALDI Imaging

Applications
| 2021 | Bruker
MALDI, MS Imaging, LC/MS, LC/Ultra-HRMS
Instrumentation
MALDI, MS Imaging, LC/MS, LC/Ultra-HRMS
Manufacturer
Bruker
Industries
Clinical Research

Novel real-time acquisition logic to prevent fragmentation of uninformative precursors

Posters
| 2023 | Bruker (ASMS)
Ion Mobility, LC/MS, LC/MS/MS, LC/TOF, LC/HRMS
Instrumentation
Ion Mobility, LC/MS, LC/MS/MS, LC/TOF, LC/HRMS
Manufacturer
Bruker
Industries
Other

4D Analysis of Lipid Nanoparticles (LNP) using Elute-timsTOF Pro 2 with VIP-HESI source

Posters
| 2023 | Bruker (ASMS)
Ion Mobility, LC/MS, LC/MS/MS, LC/HRMS, LC/TOF
Instrumentation
Ion Mobility, LC/MS, LC/MS/MS, LC/HRMS, LC/TOF
Manufacturer
Bruker
Industries
Lipidomics

High Speed, High Lateral Resolution Lipid Imaging using a timsTOF fleX

Applications
| 2019 | Bruker
Ion Mobility, MALDI, MS Imaging, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
Instrumentation
Ion Mobility, MALDI, MS Imaging, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
Manufacturer
Bruker
Industries
Lipidomics

Top-down sequencing of bispecific antibodies by electron capture dissociation on a timsOmni platform

Posters
| 2025 | Bruker (ASMS)
LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility
Instrumentation
LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility
Manufacturer
Bruker
Industries
Pharma & Biopharma
Other projects
GCMS
LCMS
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