Applications from the field of Pharma & Biopharma - page 1

Using Hydrophilic Interaction Chromatography for Heightened Product Characterization to Overcome Challenges with Hydrophobic Monoclonal Antibodies and Antibody Drug Conjugates

Applications

| 2016 | Waters

HPLC

Instrumentation

HPLC

Manufacturer

Waters

Industries

Pharma & Biopharma

Middle Down Analysis of HERCEPTIN and its Biosimilar on a Quadrupole-Ion Trap-Orbitrap Mass Spectrometer using Multiple Fragmentations

Posters

| 2020 | Thermo Fisher Scientific (ASMS)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Enhancing Subunit-Level Profiling of mAbs and ADCs with MS- Quality Difluoroacetic Acid

Posters

| 2018 | Waters

LC/HRMS, LC/MS/MS, LC/MS, LC/TOF

Instrumentation

LC/HRMS, LC/MS/MS, LC/MS, LC/TOF

Manufacturer

Waters

Industries

Pharma & Biopharma

HIGH SENSITIVITY LC-MS PROFILING OF ANTIBODY DRUG CONJUGATES WITH DIFLUOROACETIC ACID ION PAIRING AND A HIGH-COVERAGE PHENYL-BONDED STATIONARY PHASE

Posters

| 2019 | Waters (Pittcon)

HPLC

Instrumentation

HPLC

Manufacturer

Waters

Industries

Pharma & Biopharma

Improved Middle-Down Characterization of Antibodies Using Multiple Ion Activation Techniques and Ion-Ion Proton Transfer Reactions on a Modified Orbitrap Mass Spectrometer

Posters

| 2018 | Thermo Fisher Scientific (ASMS)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Middle-down Analysis of Monoclonal Antibody Middle using Nano-flow Liquid Chromatography and a Novel Tribrid Orbitrap Mass Spectrometer

Posters

| 2014 | Thermo Fisher Scientific (ASMS)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

MEETING DEMANDS FOR IMPROVED MS PERFORMANCE TO SUPPORT DEEPER PRODUCT LC-MS CHARACTERIZATION WITH MULTI-REFLECTING TOF MS TECHNOLOGY

Posters

| 2025 | Waters

LC/MS, LC/MS/MS, LC/TOF, LC/HRMS

Instrumentation

LC/MS, LC/MS/MS, LC/TOF, LC/HRMS

Manufacturer

Waters

Industries

Pharma & Biopharma

In-Depth Characterization of Monoclonal Antibodies Using Intact Mass Analysis and Middle-down Approaches on Orbitrap Ascend BioPharma Tribrid Mass Spectrometer

Posters

| 2024 | Thermo Fisher Scientific (ASMS)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Middle-Down Analyses of Unmodified and Stressed Monoclonal Antibodies Using an Orbitrap Fusion Lumos Tribrid Mass Spectrometer

Posters

| 2018 | Thermo Fisher Scientific (ASMS)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Establishment of a Robust mAb Subunit Product Quality Attribute Monitoring Method Suitable for Development, Process Monitoring, and QC Release

Applications

| 2021 | Waters

Ion Mobility, HPLC, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

Ion Mobility, HPLC, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Waters

Industries

Pharma & Biopharma