Applications from the field of Pharma & Biopharma - page 1

Analytical Workflow for Extractable and Leachable Impurities

Presentations

| 2015 | Thermo Fisher Scientific (AAPS)

GC/MSD, GC/MS/MS, GC/HRMS, GC/Orbitrap, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, ICP/MS, ICP-OES

Instrumentation

GC/MSD, GC/MS/MS, GC/HRMS, GC/Orbitrap, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, ICP/MS, ICP-OES

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Detection and identification of isotope-labeled glutathionetrapped reactive drug metabolites

Technical notes

| 2024 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, Software

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, Software

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma, Clinical Research

LC/UV/HRMS-based impurity profiling and structure elucidation of phosphoramidite raw materials used for oligonucleotide synthesis

Posters

| 2023 | Thermo Fisher Scientific (HPLC Symposium)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Confident transformation site localization of PROTAC drug metabolites facilitated by multi-stage fragmentation LC-HRAM-MS

Posters

| 2024 | Thermo Fisher Scientific (ASMS)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

LC/UV/HRAM MS-based impurity profiling and structure elucidation of phosphoramidite raw materials used for oligonucleotide synthesis

Applications

| 2023 | Thermo Fisher Scientific

Software, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

Software, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Characterization and quantification of lipid nanoparticle components and their degradants in vivo using an LC-HRAM MS platform

Posters

| 2022 | Thermo Fisher Scientific (ASMS)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Accelerating metabolite identification with mass spectrometry

Guides

| 2025 | Thermo Fisher Scientific

LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS, Software

Instrumentation

LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS, Software

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma, Metabolomics

Confident transformation site localization of PROTAC drug metabolites facilitated by multi-stage fragmentation LC-MS

Applications

| 2024 | Thermo Fisher Scientific

LC/MS, LC/HRMS, LC/MS/MS, LC/TOF

Instrumentation

LC/MS, LC/HRMS, LC/MS/MS, LC/TOF

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Confident and sensitive profiling of lipid nanoparticle raw materials and impurity identification using a LC/CAD/HRAM-MS method with inverse gradient

Applications

| 2023 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Applying UHPLC-HRAM MS technology to characterize and quantify lipid components in vivo to support new LNP development

Applications

| 2022 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma