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Applications from the field of Pharma & Biopharma | LabRulez ICPMS

Reducing Cycle Time for Charge Variant Analysis of Monoclonal Antibodies

Applications

| 2017 | Agilent Technologies

HPLC

Instrumentation

HPLC

Manufacturer

Agilent Technologies

Industries

Pharma & Biopharma

Separation of Native Monoclonal Antibodies and Identification of Charge Variants: Teamwork of the Agilent 3100 OFFGEL Fractionator, Agilent 2100 Bioanalyzer and Agilent LC/MS Systems

Applications

| 2017 | Agilent Technologies

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Agilent Technologies

Industries

Pharma & Biopharma

Automated Analytical Cation-Exchange Chromatography Fraction Collection and Structural Characterization of Monoclonal Antibody Charge Variants

Applications

| 2019 | Waters

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Waters

Industries

Pharma & Biopharma

Exploring Factors That Influence Charge Variant Analysis of mAbs with Shim-pack Bio IEX Columns using Salt Gradient Elution

Applications

| 2020 | Shimadzu

Consumables, HPLC, LC columns

Instrumentation

Consumables, HPLC, LC columns

Manufacturer

Shimadzu

Industries

Pharma & Biopharma

Evaluation and application of salt- and pH-based ion-exchange chromatography gradients for analysis of therapeutic monoclonal antibodies

Applications

| 2018 | Thermo Fisher Scientific

HPLC

Instrumentation

HPLC

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Charge variant analysis of mAb biotherapeutics by Nexera XS with a Shim-pack Bio IEX Column

Applications

| 2021 | Shimadzu

Consumables, HPLC, LC columns

Instrumentation

Consumables, HPLC, LC columns

Manufacturer

Shimadzu

Industries

Pharma & Biopharma

Online IEX-MS Characterization and Monitoring of mAb Charge Heterogeneity Using an Optimized Cation Exchange Resin and Compact TOF Mass Spectrometer

Posters

| 2019 | Waters

LC/TOF, LC/HRMS, LC/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS

Manufacturer

Waters

Industries

Pharma & Biopharma

Simple charge variant profile comparison of an innovator monoclonal antibody and a biosimilar candidate

Applications

| 2018 | Thermo Fisher Scientific

HPLC

Instrumentation

HPLC

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Using the NISTmAb reference standard to demonstrate a simple approach to charge variant analysis

Applications

| 2017 | Thermo Fisher Scientific

Consumables, HPLC

Instrumentation

Consumables, HPLC

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Fast acquisition of DDA-MS/MS of oligonucleotides and the novel spectral merging algorithm for better assignment of sequence information

Posters

| 2023 | Shimadzu (ASMS)

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Shimadzu

Industries

Pharma & Biopharma

"The first science communicators for me were already high school teachers,” says researcher and laureate of the Learned Society of the Czech Republic award, Barbora Rudzanová.

Su, 2.6.2024

RECETOX - Centrum pro výzkum toxických látek v prostředí

‌

From a scientific project to a global business venture. The company mzio is striving to improve data analysis in mass spectrometry labs

We, 29.5.2024

Ústav organické chemie a biochemie AV ČR

‌

Cryo-EM structures show how Trypanosomes escape the human innate immune response

Tu, 28.5.2024

Ústav organické chemie a biochemie AV ČR

‌

Other projects

More information

Webinars About us Contact us Terms of use

Applications from the field of Pharma & Biopharma | LabRulez ICPMS

Reducing Cycle Time for Charge Variant Analysis of Monoclonal Antibodies

Separation of Native Monoclonal Antibodies and Identification of Charge Variants: Teamwork of the Agilent 3100 OFFGEL Fractionator, Agilent 2100 Bioanalyzer and Agilent LC/MS Systems

Automated Analytical Cation-Exchange Chromatography Fraction Collection and Structural Characterization of Monoclonal Antibody Charge Variants

Exploring Factors That Influence Charge Variant Analysis of mAbs with Shim-pack Bio IEX Columns using Salt Gradient Elution

Evaluation and application of salt- and pH-based ion-exchange chromatography gradients for analysis of therapeutic monoclonal antibodies

Charge variant analysis of mAb biotherapeutics by Nexera XS with a Shim-pack Bio IEX Column

Online IEX-MS Characterization and Monitoring of mAb Charge Heterogeneity Using an Optimized Cation Exchange Resin and Compact TOF Mass Spectrometer

Simple charge variant profile comparison of an innovator monoclonal antibody and a biosimilar candidate

Using the NISTmAb reference standard to demonstrate a simple approach to charge variant analysis

Fast acquisition of DDA-MS/MS of oligonucleotides and the novel spectral merging algorithm for better assignment of sequence information

Related content

"The first science communicators for me were already high school teachers,” says researcher and laureate of the Learned Society of the Czech Republic award, Barbora Rudzanová.

From a scientific project to a global business venture. The company mzio is striving to improve data analysis in mass spectrometry labs

Cryo-EM structures show how Trypanosomes escape the human innate immune response