Applications from the field of Clinical Research | LabRulez ICPMS

Improving MS Response in the Analysis of Free Fatty Acids Through Structural Considerations

Technical notes

| 2019 | Waters

HPLC

Instrumentation

HPLC

Manufacturer

Waters

Industries

Clinical Research

Extending the Lower Limits of Quantification of a Therapeutic Oligonucleotide Through Microflow LC-MS/MS

Applications

| 2019 | SCIEX

LC/MS, LC/MS/MS, LC/QTRAP

Instrumentation

LC/MS, LC/MS/MS, LC/QTRAP

Manufacturer

SCIEX

Industries

Clinical Research

Better Separation Resolution of New Biopharmaceutical Modalities through Fine Tuning of the Temperature with CE-SDS

Applications

| 2020 | SCIEX

Capillary electrophoresis

Instrumentation

Capillary electrophoresis

Manufacturer

SCIEX

Industries

Clinical Research

A Generic Kit-Based Approach for Quantifying Monoclonal Antibody Drugs Through Direct Digestion of Discovery Study Samples

Applications

| 2015 | Waters

Consumables, LC/MS, LC/MS/MS, LC/QQQ

Instrumentation

Consumables, LC/MS, LC/MS/MS, LC/QQQ

Manufacturer

Waters

Industries

Clinical Research

Developing a Quantitative Surrogate Peptide Assay – Peptide mapping through MRM Optimization for Measuring Dulaglutide in a Rat PK Study

Applications

| 2020 | Waters

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS, LC/QQQ

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS, LC/QQQ

Manufacturer

Waters

Industries

Proteomics , Clinical Research

High Throughput Quantitation of 46 Histone PTMs through Unscheduled SRM-based Method Development on a Nano-HPLC Triple Quadrupole Platform

Posters

| 2015 | Thermo Fisher Scientific

LC/MS, LC/MS/MS, LC/QQQ

Instrumentation

LC/MS, LC/MS/MS, LC/QQQ

Manufacturer

Thermo Fisher Scientific

Industries

Clinical Research

Characterization of Monoclonal Antibody Biosimilar through C-terminal and Disulfide Bond Peptides Sequencing Analysis on Q-TOF Mass Spectrometer

Applications

| 2020 | Shimadzu

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Shimadzu

Industries

Clinical Research

Improving the Cleanliness of DBS Extracts using the Ostro Pass-through 96-well Sample Preparation Plate and Single Step Method

Applications

| 2014 | Waters

Sample Preparation, Consumables, LC/MS, LC/MS/MS, LC/QQQ

Instrumentation

Sample Preparation, Consumables, LC/MS, LC/MS/MS, LC/QQQ

Manufacturer

Waters

Industries

Clinical Research

Identifying Antibiotic Resistance Through Direct Detection of Intact Enzymes from Bacterial Lysates using LC-MS/MS: Exploring MRSA and Carbapenem Resistance

Posters

| 2021 | Thermo Fisher Scientific (ASMS)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Clinical Research

Workflow Automation for LC/MS: In-Solution Protein Digestion, Peptide Cleanup, and Strong Cation-Exchange Fractionation of Peptides Enabled by AssayMAP Technology

Applications

| 2016 | Agilent Technologies

Sample Preparation, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

Sample Preparation, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Agilent Technologies

Industries

Clinical Research

Applications from the field of Clinical Research | LabRulez ICPMS

Improving MS Response in the Analysis of Free Fatty Acids Through Structural Considerations

Extending the Lower Limits of Quantification of a Therapeutic Oligonucleotide Through Microflow LC-MS/MS

Better Separation Resolution of New Biopharmaceutical Modalities through Fine Tuning of the Temperature with CE-SDS

A Generic Kit-Based Approach for Quantifying Monoclonal Antibody Drugs Through Direct Digestion of Discovery Study Samples

Developing a Quantitative Surrogate Peptide Assay – Peptide mapping through MRM Optimization for Measuring Dulaglutide in a Rat PK Study

High Throughput Quantitation of 46 Histone PTMs through Unscheduled SRM-based Method Development on a Nano-HPLC Triple Quadrupole Platform

Characterization of Monoclonal Antibody Biosimilar through C-terminal and Disulfide Bond Peptides Sequencing Analysis on Q-TOF Mass Spectrometer

Improving the Cleanliness of DBS Extracts using the Ostro Pass-through 96-well Sample Preparation Plate and Single Step Method

Identifying Antibiotic Resistance Through Direct Detection of Intact Enzymes from Bacterial Lysates using LC-MS/MS: Exploring MRSA and Carbapenem Resistance

Workflow Automation for LC/MS: In-Solution Protein Digestion, Peptide Cleanup, and Strong Cation-Exchange Fractionation of Peptides Enabled by AssayMAP Technology

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