Applications from the field of Clinical Research - page 1

Drug to Antibody Ratio Analysis of Brentuximab Vedotin in Monkey Plasma

Applications

| 2024 | Agilent Technologies

LC/HRMS, LC/MS, LC/MS/MS, LC/TOF

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/TOF

Manufacturer

Agilent Technologies

Industries

Clinical Research

Routine analysis of drug to antibody ratio and drug distribution with maXis II

Applications

| 2020 | Bruker

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Bruker

Industries

Clinical Research

Determination of Drug-to-Antibody Ratio for Antibody-Drug Conjugates Purified from Serum

Applications

| 2016 | Agilent Technologies

Sample Preparation, Software, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

Sample Preparation, Software, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Agilent Technologies

Industries

Clinical Research

Determination of Full, Partial and Empty Capsid Ratios for Adeno-Associated Virus (AAV) Analysis

Applications

| 2020 | SCIEX

Capillary electrophoresis

Instrumentation

Capillary electrophoresis

Manufacturer

SCIEX

Industries

Clinical Research

An AdvanceBio HIC Column for Drug‑to-Antibody Ratio (DAR) Analysis of Antibody Drug Conjugates (ADCs)

Applications

| 2018 | Agilent Technologies

HPLC

Instrumentation

HPLC

Manufacturer

Agilent Technologies

Industries

Clinical Research

Antibody-Drug Conjugate (ADC) Drug-to-Antibody Ratio (DAR) Analysis in Serum Using IA-LC-HRMS

Applications

| 2019 | Waters

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Waters

Industries

Clinical Research

FAIMS Improves the Signal-to-Noise Ratio when Performing Targeted LC-MS/MS Measurements of Interference-Prone Analytes

Posters

| 2022 | Thermo Fisher Scientific (ASMS)

LC/MS, LC/MS/MS, LC/QQQ

Instrumentation

LC/MS, LC/MS/MS, LC/QQQ

Manufacturer

Thermo Fisher Scientific

Industries

Clinical Research

Analysis of Full/Empty Capsid Ratios in Adeno-Associated Virus 1 and 6 Serotypes Using Biocompatible Liquid Chromatography

Applications

| 2022 | Agilent Technologies

Consumables, HPLC, LC columns

Instrumentation

Consumables, HPLC, LC columns

Manufacturer

Agilent Technologies

Industries

Clinical Research

Automating the Determination of Drug-to-Antibody Ratio (DAR) of Antibody Drug Conjugates (ADCs) Based on Separation by Hydrophobic Interaction Chromatography (HIC)

Applications

| 2014 | Waters

HPLC

Instrumentation

HPLC

Manufacturer

Waters

Industries

Clinical Research

Fast, Reproducible LC-MS/MS Analysis of Dextromethorphan and Dextrorphan

Applications

| 2013 | Thermo Fisher Scientific

Sample Preparation, Consumables, LC/MS, LC/MS/MS, LC/QQQ

Instrumentation

Sample Preparation, Consumables, LC/MS, LC/MS/MS, LC/QQQ

Manufacturer

Thermo Fisher Scientific

Industries

Clinical Research