Applications from the field of Clinical Research | LabRulez ICPMS

Enabling Routine and Reproducible Intact Mass Analysis When Data Integrity Matters

Applications

| 2019 | Waters

LC/TOF, LC/HRMS, LC/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS

Manufacturer

Waters

Industries

Clinical Research

Incorporating CCS values to enable 4-dimensional annotation of metabolic features

Applications

| 2020 | Bruker

Ion Mobility, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

Ion Mobility, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Bruker

Industries

Clinical Research

Utilizing UPLC Separation to Enable the Analysis of 19 Steroid Hormones in Serum for Clinical Research

Applications

| 2020 | Waters

LC/MS, LC/MS/MS, LC/QQQ

Instrumentation

LC/MS, LC/MS/MS, LC/QQQ

Manufacturer

Waters

Industries

Clinical Research

Isotopically Resolved Subunit Analysis for Tracking Protein Therapeutic Stress Studies

Applications

| 2018 | SCIEX

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

SCIEX

Industries

Clinical Research

Rapid Identification of Major Metabolites of Gefitinib Using Ion Mobility Enabled MS (HDMSE) with the SYNAPT XS

Applications

| 2020 | Waters

Ion Mobility, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

Ion Mobility, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Waters

Industries

Metabolomics, Clinical Research

A Clinical Research Method for the Measurement of Low- Level Testosterone in Serum using Differential Mobility Separation with LC-MS/MS

Applications

| 2020 | SCIEX

LC/MS, LC/MS/MS, LC/QQQ

Instrumentation

LC/MS, LC/MS/MS, LC/QQQ

Manufacturer

SCIEX

Industries

Clinical Research

Real-Time Search enables a new gold standard for TMT quantitation accuracy on the Orbitrap Eclipse Tribrid mass spectrometer

Applications

| 2020 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Clinical Research

Automation for LC/MS Sample Preparation: High Throughput In-Solution Digestion and Peptide Cleanup Enabled by the Agilent AssayMAP Bravo Platform

Applications

| 2016 | Agilent Technologies

Sample Preparation, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

Sample Preparation, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Agilent Technologies

Industries

Clinical Research

Ion Mobility-enabled Data-dependent Experiments Distinguishing Co-eluting Isomeric Metabolites Using an IMS-QTof Mass Spectrometer

Applications

| 2017 | Waters

Ion Mobility, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

Ion Mobility, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Waters

Industries

Metabolomics, Clinical Research

Workflow Automation for LC/MS: In-Solution Protein Digestion, Peptide Cleanup, and Strong Cation-Exchange Fractionation of Peptides Enabled by AssayMAP Technology

Applications

| 2016 | Agilent Technologies

Sample Preparation, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

Sample Preparation, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Agilent Technologies

Industries

Clinical Research

Applications from the field of Clinical Research | LabRulez ICPMS

Enabling Routine and Reproducible Intact Mass Analysis When Data Integrity Matters

Incorporating CCS values to enable 4-dimensional annotation of metabolic features

Utilizing UPLC Separation to Enable the Analysis of 19 Steroid Hormones in Serum for Clinical Research

Isotopically Resolved Subunit Analysis for Tracking Protein Therapeutic Stress Studies

Rapid Identification of Major Metabolites of Gefitinib Using Ion Mobility Enabled MS (HDMSE) with the SYNAPT XS

A Clinical Research Method for the Measurement of Low- Level Testosterone in Serum using Differential Mobility Separation with LC-MS/MS

Real-Time Search enables a new gold standard for TMT quantitation accuracy on the Orbitrap Eclipse Tribrid mass spectrometer

Automation for LC/MS Sample Preparation: High Throughput In-Solution Digestion and Peptide Cleanup Enabled by the Agilent AssayMAP Bravo Platform

Ion Mobility-enabled Data-dependent Experiments Distinguishing Co-eluting Isomeric Metabolites Using an IMS-QTof Mass Spectrometer

Workflow Automation for LC/MS: In-Solution Protein Digestion, Peptide Cleanup, and Strong Cation-Exchange Fractionation of Peptides Enabled by AssayMAP Technology

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