Analytical Scientist (UPLC, RP-HPLC, SEC, HIC, IEX, UV-Vis)

Our passion for science and technology is what drives our more than 64,000 employees across 66 countries to find solutions to some of today’s toughest challenges and create more sustainable ways to live.

We are here for people at every step, helping create, improve and prolong life. We deliver personalized treatments for serious diseases and enable people to achieve their dream of becoming parents. We empower the scientific community. Our tools, services, and digital platform make research simpler, more exact, and help to deliver breakthroughs more quickly. We provide progressive treatment solutions that help improve access to health thanks to the accuracy of our tests and the reliability of our medicine. As a company, we are at the forefront of digital living. Our science sits inside technologies that change the way we access, store, process, and display information. Our innovative technology drives human progress and opens new possibilities to transform life on Earth as we know it.

Thanks to the constant curiosity of our employees, we are making discoveries that can change the landscape of entire industries. For more than 350 years, we’ve been pushing the boundaries of what’s possible, and we’ll continue to do so in the years to come.

ANALYTICAL SCIENTIST (UPLC, RP-HPLC, SEC, HIC, IEX, UV-Vis)

Work Your Magic with us!

Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.

Your Role:

MilliporeSigma is looking for an Analytical Scientist to add to the team at our Cherokee site. In this role, you’ll be working in the Contract Testing, Development, and Manufacturing Organization (CTDMO) within the Life Sciences group of MilliporeSigma. This role will serve as an individual contributor in the Process and Analytical Development organization. You will be involved in working in a lab setting on analytical method development and optimization for external customers in the field of Antibody Drug Conjugates (ADC). The role will require problem solving, working within project timelines, and contributing to documentation for method qualification and transfer into GMP manufacturing and quality control organizations.

This role will be reporting to Robert Guilmett.

• Perform hands-on work executing analytical methods.

• Qualify and transfer analytical methods into Quality Control to support GMP release testing.

• Document and communicate experimental results with strong customer-facing skills. 

• Promptly deliver data, adhering to ALCOA+ principles for proper data documentation, and make data-driven decisions.

• Independent management of daily activities lead project initiatives and lead process improvement initiatives.

• Act as a mentor to less experienced scientists, evolving into an emerging subject matter authority capable of troubleshooting issues as they emerge.

Who You Are:

Minimum Qualifications:

• Bachelor’s Degree in Chemistry, Biochemistry, Engineering, or other scientific discipline with 3+ years' experience in method development within a GMP/pre-GMP environment.
  OR
• Master’s Degree in Chemistry, Biochemistry, Engineering, or other scientific discipline with 1+ years' experience in method development within a GMP/pre-GMP environment.
  OR
• Ph.D in Chemistry, Biochemistry, Engineering, or other scientific discipline.

Preferred Qualifications:

• Hands-on experience in separation science, notably the theory, operation, data interpretation and troubleshooting of UPLC, RP-HPLC, SEC, HIC and/or IEX.

• Experience with protein analytics and spectroscopy (UV and slope).

• Prior experience working with customers and matrix teams.

• Working knowledge of Microsoft Office suite and digital documentation (modern data acquisition systems and electronic notebooks).

What we offer:

We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We celebrate all dimensions of diversity and believe that it drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of our diverse team!

If you would like to know more about what diversity, equity, and inclusion means to us, please visit

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